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    Top 10 Medical & Technological AdvancesThat Could Help You Live 1,000 YearsPOSTED BY JIM CISCELLON JULY 31, 2012 IN BIZARRE, SCIENCE| 3103 VIEWS | 12

    RESPONSESCelebrating TopTenz.nets 1,000th listcoming up on August 3, 2012, here is our 2nd list this

    week about the number 1,000.

    In 1974, Gene Wilder, playing Dr. Frederick Frankenstein, screamed in an annoyed tone

    at a young medical student, Hearts and kidneys are tinker toys I!m talking a"out t#e

    central ner$ous system% &s long as t#ere #as "een science 'ction, t#ere #as "een

    speculation a"out longer(lasting li)e. Here are tec#nologies and medical ad$ances

    actually "eing discussed or *orked on, t#at could one day allo* people to li$e to "e a

    t#ousand years old.

    10. Neuroprosthetics

    +europrost#etics are implants placed on a ner$e, or onto t#e central ner$ous system,in order to replace mo"ility lost "y accident or disease. otor )unctionality in t#e "ody

    reacts to outside stimuli, *#et#er it is natural or un(natural. +europrost#etics could

    not only one day allo* people *it# lost lim"s to replace t#ose lim"s, "ut also may

    ser$e as a replacement parts directory )or most )unctions o) t#e #uman "ody.

    http://www.toptenz.net/author/jamesciscellhttp://www.toptenz.net/lists/bizarrehttp://www.toptenz.net/lists/sciencehttp://www.toptenz.net/top-10-ways-sci-fi-could-help-you-live-1000-years.php#commentshttp://www.toptenz.net/top-10-ways-sci-fi-could-help-you-live-1000-years.php#commentshttp://www.toptenz.net/top-10-complaints-about-toptenz-why-toptenz-sucks.phphttp://www.toptenz.net/top-10-complaints-about-toptenz-why-toptenz-sucks.phphttp://www.toptenz.net/top-10-mad-scientists-in-the-movies.phphttp://www.toptenz.net/lists/bizarrehttp://www.toptenz.net/lists/sciencehttp://www.toptenz.net/top-10-ways-sci-fi-could-help-you-live-1000-years.php#commentshttp://www.toptenz.net/top-10-ways-sci-fi-could-help-you-live-1000-years.php#commentshttp://www.toptenz.net/top-10-complaints-about-toptenz-why-toptenz-sucks.phphttp://www.toptenz.net/top-10-mad-scientists-in-the-movies.phphttp://www.toptenz.net/author/jamesciscell
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    +europrost#etics #old t#e ultimate key to replacing damaged "ody parts and allo*ing

    t#em to sync up *it# your normal "rain )unctions. &s long as -te$e artin!s The an

    !ith Two "rains euation t#at your "rain dies last% #old true, t#en you can one day

    #a$e a "ody o) replacement parts ri$aling -te$e &ustin!s,controlled "y

    neuroprost#etics.

    In s#ort, neuroprost#etics may, one day, gi$e us /uke -ky*alker!s #and, 0o"ocop!s

    "ody, or y"org!s cy"ernetic parts.

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    9. Brain-Computer Interface

    0emem"er in The atri#, *#en +eo #ad t#e super needle put into t#e "ack o) #is neck

    t#at taug#t #im kung()u3 Welcome to t#e eciting *orld o) "rain(computer inter)aces.

    5#is is a real t#ing and *ill really make you say *#oa.% & "rain(computer inter)ace is a

    direct link "et*een an outside mac#ine, and a neurological process *it#in t#e "rain orner$e ending itsel).

    In s#ort, a "rain computer inter)ace can interact *it# an eisting neural )unction to

    restore cogniti$e a"ilities and )unctions. I) t#e synapses *it#in t#e "rain are not

    *orking properly, t#e 6rain omputer Inter)ace can ack into t#e "rain and restore

    http://www.toptenz.net/top-10-best-pro-wrestling-video-games.phphttp://www.toptenz.net/top-10-best-pro-wrestling-video-games.phphttp://www.ncbi.nlm.nih.gov/pubmed/15171589http://sciencelife.uchospitals.edu/2010/03/08/luke-skywalkers-hand-and-how-touch-is-like-vision/http://www.toptenz.net/top-ten-time-travel-movies.phphttp://www.toptenz.net/top-10-best-pro-wrestling-video-games.phphttp://www.ncbi.nlm.nih.gov/pubmed/15171589http://sciencelife.uchospitals.edu/2010/03/08/luke-skywalkers-hand-and-how-touch-is-like-vision/http://www.toptenz.net/top-ten-time-travel-movies.php
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    motor )unctions. 8rgo and t#ere)ore, t#ere *ould "e no reason )or t#e "rain damage

    to "e permanent.

    -cience is getting closer to "eing a"le to restore )unctions. Ho*e$er, *#y on eart#

    *ould you stop at restoring, *#en t#e net logical step *ould "e en#ancing *#at isalready t#ere3 6rain(computer inter)aces not only #old t#e key to repairing damaged

    )unctions, "ut to also en#ancing already eisting ones. W#oa,% indeed.

    Welcome to eternal li)e and a red "elt.

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    8. DNA Repair

    http://www.neilsquire.ca/research-development/projects-activities/the-brain-computer-interface-project/http://cyborganthropology.com/Brain-Computer_Interfacehttp://www.neilsquire.ca/research-development/projects-activities/the-brain-computer-interface-project/http://cyborganthropology.com/Brain-Computer_Interface
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    :eople may t#ink t#at D+& is like a dusty set o) "lueprints. 5#e D+& is t#ere *#en you

    are "orn, and t#ere *#en you die. Ho*e$er, D+& is muc# more t#an t#at. D+& can

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    act a computer *it#in t#e cell directing de$elopment, as *ell as repairing damage to

    t#e cell itsel).

    In s#ort, t#e key to long(lasting li)e, and getting into 6i"licaland $ord o% the

    &ings territory, rests greatly on t#e a"ility o) t#e D+& to adapt and, yes, mutateto deal*it# damages. For instance, cancer is a "reakdo*n o) D+&!s a"ility to repair itsel), as

    *ell as a mutation. 5#e key actually lies in kno*ing enoug# a"out t#e D+& to 'gure

    out #o* to umpstart our natural process at optimum le$els. For instance, *orking

    *it# mice, t#e deletion o) a single protein restores t#e D+&, and repairs natural

    )unction.

    In essence, D+& is like a car engine. Wit# regular tune(ups and c#anges, t#ere is no

    reason not to "elie$e t#at t#e "ody is capa"le o) restoring itsel) into in'nity. ;) course,

    once *e 'gure out #o* to restore t#e D+& repair a"ility, t#en Wol$erine *ill "e ustanot#er guy *it# a really "ad #aircut. /ogan!s #ealing )actor% is merely D+& repair on

    a

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    5#e more aging is studied, t#e more it seems like it s#ould "e treated as a disease. 5o

    t#is point, aging does not appear to "e as natural a process as *e mig#t t#ink. 0at#er,

    aging is an attack on our eisting processes. 5#e e=ects o) aging are starting to "e

    traced to speci'c en>ymes. I) t#ose en>ymes can "e repaired, t#en t#e restoration o)

    t#eir natural )unctionality *ould seem to eliminate t#e need )or aging altoget#er.

    5#us, anti(aging en>ymes #old t#e key. & study, concluded in 2??7, disco$ered t#at t*o

    en>ymes @-I05A and -I054B, play a key role in t#e mitoc#ondrial di$ision o) cells. 5#e

    loss o) t#e cells! a"ility to di$ide, and reproduce, lead to many o) t#e e=ects t#at *e

    re)er to as aging%. 5#ese t*o en>ymes )unction as cell "atteries.% &s t#ese "atteries,

    and production o) t#ese en>ymes *ane, t#en *e get many o) t#e e=ects o) aging. I)

    science is a"le to restore t#e a"ility to produce, or t#e )unctionality o) t#e en>ymes in

    t#e #uman "ody, t#en again t#ere is no reason *#y t#e natural e=ects o) aging cannot

    "e stopped or, ultimately, re$ersed.

    5#ese t*o genes are no* "eing *orked on as drug targets, to slo* do*n and possi"ly

    stop t#e e=ects o) aging altoget#er. 5#ey #a$e s#o*ed t#at *#en cells are put under

    stress, suc# as *#en calories are restricted, t#e t*o genes go into action and protect

    cells )rom t#e diseases o) aging.

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    5#e a"ility to elongate li)e "y studying -I05A and -I054 are o"$ious. 5#e only #ope is

    t#at t#e drugs *ill come in t#e )orm o) a pool *#ic# you "at#e in to restore your cell

    "atteries once e$ery )e* years. -I05A and -I054 may t#an #old t#e key to t#e Cuid

    )ound in :once De/eon!s Fountain o) out#, or 0a!s &l G#ul!s/a>arus :it.

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    ". #artia$ Brain %ransp$ants

    any o) t#e ins and outs o) #o* t#e "rain actually *orks are still a great mystery.

    Ho*e$er, it #as "een pro$en, *it# mice, t#at putting t#e correct tissue in t#e correct

    part o) t#e "rain may "e enoug# to allo* t#e "rain!s neuro(net to restore itsel). 1n

    19E2, Dr. Dorot#y 5. rieger "red t*o di=erent types o) mice. ;ne set o) mice *as

    per)ectly normal. 5#e altered strain o) mice lacked /.H.0.H @luteini>ing #ormone

    releasing #ormoneB. no*ing eactly *#ere t#e #ormone *as located in t#e "rain, Dr.

    reiger remo$ed t#e production center, *#ic# *as smaller t#an t#e #ead o) a matc#,

    and success)ully implanted t#e center into t#e "rains o) t#e de'cient mice.

    &D805I-88+5

    http://www.toptenz.net/top-10-immortals.phphttp://www.medicalnewstoday.com/articles/83268.phphttp://www.fiercebiotechresearch.com/story/anti-aging-study-finds-enzymes-protect-cells/2007-09-25http://www.toptenz.net/top-10-immortals.phphttp://www.medicalnewstoday.com/articles/83268.phphttp://www.fiercebiotechresearch.com/story/anti-aging-study-finds-enzymes-protect-cells/2007-09-25
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    5#e implanted section o) "rain started to connect and gro* naturally. +ot only did t#e

    piece o) t#e "rain connect, "ut t#e "rain also started to produce /.H.0.H. 5#e real

    c#allenge may lie in success)ully mapping t#e "rain, and kno*ing *#ere to input

    #ealt#y sections.

    In recent years, t#e tec#nology #as mo$ed to a$ian areas. ells )rom t#e "rain o) a

    'nc# #a$e "een success)ully transplanted into ac#icken, complete *it# altered

    auditory and $ocal responses.

    W#en science kno*s eactly *#ic# cells to put into t#e correct part o) t#e "rain, you

    could t#en potentially seed% a "rain. Wit# proper nouris#ment, t#e "rain seeds can

    gro* naturally, and t#e "rain itsel) *ill direct t#e reco$ery and implementation. &s long

    as t#e "rain can seed%, t#en t#e "rain can gro*)or a possi"ly in'nite time )rame.

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    &. 'rgan #rinting

    ;rgan donation may one day gi$e *ay to organ printing. 5aking generated cells, t#e

    t#eoretical organ printers *ould "uild a *orking organ one layer at a time. 5#is *ould

    http://www.toptenz.net/top-10-videogames-that-punish-you-for-being-a-jerk.phphttp://www.toptenz.net/top-10-videogames-that-punish-you-for-being-a-jerk.phphttp://www.nytimes.com/1982/06/18/us/transplant-success-reported-with-part-of-a-mouse-s-brain.htmlhttp://www.toptenz.net/top-10-videogames-that-punish-you-for-being-a-jerk.phphttp://www.nytimes.com/1982/06/18/us/transplant-success-reported-with-part-of-a-mouse-s-brain.html
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    "e in muc# t#e same *ay t#at an old dot matri printer *ould "uild% a line o) tet.

    -ince t#e cells *ould come )rom t#e patient t#emsel$es or a matc#ed type, t#ere

    *ould "e little )ear o) t#e "ody reecting t#e organs.

    &s a matter o) )act, a sample o) e$ery type o) cell "eing taken )rom a "ody could"ecome common place. -cientists are currently *orking on simple replacements, suc#

    as a "lood $essel. &s successes mount, t#e compleity o) t#e organs printed *ould

    "ecome more comple. 8$en i) t#e organ is damaged "eyond repair, ne* ones could

    "e gro*n to maturity, and t#en transplanted.

    :eople, *e are ocially entering into t#e realm o) t#e -tar 5rek replicator, and possi"ly

    t#e medical tri(corder. 5#ink it is ust science 'ction3 5#e ni$ersity o) issouriis

    acti$ely *orking on t#e "lood $essel as *e speak. I) success)ul, t#e tec#nology can only

    "ecome more ad$anced )rom t#ere. Imagine a *orld in *#ic# deceased donors arenot e$en needed. &ll t#at is needed is some cells and a mac#ine to print a *orking

    organ ready )or insertion, *it#out )ear o) t#e "ody reecting it. 5#ey *ill #a$e to put a

    t#ousand(year(and(up% category in t#e ;lympics.

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    (. Artificia$ 'rgans

    http://www.toptenz.net/top-10-unique-objects-creatures-and-world-events.phphttp://discovermagazine.com/2006/jun/i-grow-organs/http://organprint.missouri.edu/www/http://www.toptenz.net/top-10-unique-objects-creatures-and-world-events.phphttp://discovermagazine.com/2006/jun/i-grow-organs/http://organprint.missouri.edu/www/
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    ;) course, not e$eryt#ing #as to "e as #ome gro*n% as it mig#t sound. In t#e

    mo$ie&obocop, t#ere *as not muc# o) a "ody to sal$age. 5#ere is also al*ays t#e #ope

    t#at one day t#at t#ere *ill "e )ully reali>ed cy"ernetic se toys *it# #uman skin. ;r

    5erminatorsor #ot c#icks *it# tails, like in Trans%ormers' &e(enge o% the )allen. We are

    not picky, as long as t#ere is a catalog.

    5#e ad$ances in arti'cial organs, o$er t#e years, #a$e "een particularly striking. In

    19E2,6arneylark recei$ed t#e 'rst arti'cial #eart. lark *as deemed to "e too muc#

    o) a risk )or a #eart transplant, lea$ing an arti'cial de$ice pioneered "y Dr. 0o"ert

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    arti'cial #eart tec#nology #a$e led to *#at is kno*n as t#e 5otal &rti'cial Heart. 5#e

    5otal &rti'cial Heart completely replaces t#e "ottom t*o $entricles o) t#e #eart.

    :atients can no* li$e se$eral years on 5otal &rti'cial Hearts. 5otal &rti'cial Hearts are

    no* also "eing de$eloped )or, and #a$e "een success)ully implemented in,

    adolescents.

    ;) course, )or t#e moment, arti'cial organs are only a stop(gap measure, until donor

    organs can "e )ound. Ho*e$er, as ad$ances gro*, t#ere is no reason *#y, one day,

    you could "e potentially telling someone I!ll "e "ack,% and +;5 get punc#ed in t#e )ace

    "y0oger 8"ert)or mindlessly uoting t#at damn 'lm yet &G&I+.

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    ). Do*n$oa+ing ,our Consciousness

    https://twitter.com/ebertchicago/statuses/224303615718854656http://www.wired.com/thisdayintech/2009/12/dayintech_1202jarvikhearthttp://www.chinapost.com.tw/health/heart/2009/02/19/196841/p2/Locally-developed.htmhttp://www.nhlbi.nih.gov/health/health-topics/topics/tah/https://twitter.com/ebertchicago/statuses/224303615718854656http://www.wired.com/thisdayintech/2009/12/dayintech_1202jarvikhearthttp://www.chinapost.com.tw/health/heart/2009/02/19/196841/p2/Locally-developed.htmhttp://www.nhlbi.nih.gov/health/health-topics/topics/tah/
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    ou *ill one day @according to some scientistsB "e a"le to "ecome your o*n g#ost in

    t#e mac#ine.% 6asically, a computer *it# all o) your in)ormation on it, as *ell as

    arti'cial intelligence, *ould allo* you to li$e% in t#e computer )or a t#ousand years or

    more. 5#e claim is made "y scientist Ian :earson, and #e is de$eloping computer

    models as *e speak. -o "y 2?J?, i) you make it till t#en, you can #a$e your o*n

    silicone soul%. Hope)ully it!ll *ork out "etter t#an t#e 6ruce WayneK6atmanmodel

    s#o*n a"o$e.

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    . uspen+e+ Animation

    ;ne o) t#e primary pro"lems *it# e$en(t#eoretical immortality is t#at in$ulnera"ility is

    not part o) t#e deal. 6ullets, kni$es, #and grenades, and "om"s all still #a$e an e=ect.

    5#ere are also some parts o) t#e *orld *#ere t#ose t#ings are considered to "e part

    o) e$eryday li)e. -tatistically, "attle'eld deat#s occur most o)ten *#en a medical team

    cannot get to t#e patient *it#in t#e 'rst #our. 5#is is re)erred to as t#e golden #our.%

    5#e uestion "ecomes t#en, *#at i) you could press t#e pause "utton3%

    5#at is eactly t#e uestion t#at t#e De)ense &d$anced 0esearc# :roects &gency, and

    t#e 5eas & L Institute For :reclinical -tudies, are *orking on no*. 5#oug# t#e

    initial study is )ocused on suirrels, t#e attempt is no* to put pigs to #i"ernated sleep.

    es, a >om"ie pig% may one day #old t#e key to getting soldiers treatment during t#e

    http://www.toptenz.net/top-10-portrayals-of-batman.phphttp://www.guardian.co.uk/science/2005/may/22/theobserver.technologyhttp://www.toptenz.net/top-10-strangest-flying-animals.phphttp://www.toptenz.net/top-10-portrayals-of-batman.phphttp://www.guardian.co.uk/science/2005/may/22/theobserver.technologyhttp://www.toptenz.net/top-10-strangest-flying-animals.php
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    golden #our%, #yper(sleep in transport to anot#er planet, and 0ip an Winkling your

    *ay to romancing yclopian mutants *#ile *orking )or *lanet +#press.

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    1. /ho$e ea+ An+ /ho$e Bo+! %ransp$ants

    5#e "rain itsel) is *#at is kno*n as autoimmune. 5#is means t#at a #ost "ody *ould

    not actually reect a "rain t#e same *ay it *ould reect, say, a li$er or kidneys. 5#e

    c#allenge comes not in transplanting t#e "rain "ut, rat#er, in remo$ing and re(

    attac#ing t#e #ead. 5#is makes t#e pro"lem *it# #ead or *#ole "ody% transplants t#e

    success)ul remo$al and attac#ment. & success)ul operation *ould also #a$e to attac#

    to t#e ner$ous system in suc# a *ay t#at t#e resulting patient is not a uadriplegic.

    Ho*e$er, t#e procedure #as "een success)ully done *it# smaller animals. In 2??1, Dr.

    0o"ert W#ite transplanted t#e #ead o) a monkey onto anot#er "ody. For a timea)ter*ards, t#e animal actually li$ed. Gi$en all o) t#e ad$anced, a scientist may one day

    scream at you, It!s &/I8%, and r. 8"ert *ould "e kept at "ay once again.

    I) t#e "ody is going to continue to )ail, t#en t#e last resort *ould "e to keep getting a

    steady supply o) ne* "odies. We guess you!d need one a"out e$ery sity years or so.

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    http://news.bbc.co.uk/2/hi/health/1263758.stmhttp://www.pbs.org/wgbh/nova/body/brain-transplants.htmlhttp://news.bbc.co.uk/2/hi/health/1263758.stmhttp://www.pbs.org/wgbh/nova/body/brain-transplants.html