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    EFFECTS OF TOBACCO SMOKE AND ITS TOXIC

    COMPONENTS ON THE RESPIRATORY SYSTEM

    Tobacco is made from the dried leaves of the tobacco plant. The majority of tobacco consumed is in

    the form of cigarettes. After the leaves are dried they are treated with around 4000 different

    chemicals before being made into cigarettes. Many of these chemicals are known carcinogens

    (cancer causing), and tobacco smoke itself is carcinogenic.

    Some facts about cigarette smoke

    Cigarette smoke contains thousands of chemicals including:

    Nicotine an addictive drug that affects brain and muscle activity and increases your bloodpressure, making your heart work harder

    Carbon monoxide a poisonous gas that replaces oxygen in your blood, making your heart beatfaster

    Tar a sticky substance that coats your lungs like soot in a chimney, making it harder for you tobreathe, and that contains dozens of chemicals that cause cancer.

    The risks of cigarette smoking

    If you smoke, your risk of:

    Heart attack is increased by two to six times Coronary heart disease is increased if you are a woman using the contraceptive pill Stroke is increased by three times Peripheral arterial disease, which can lead to gangrene, is increased by more than five times.

    Second-hand smoke is a health hazard

    Exposure to second-hand smoke (passive smoking) is a serious health hazard for smokers and non-

    smokers. People who inhale smoke from others are at increased risk of disease.

    Non-smokers living with smokers have about a 30 per cent increase in risk of heart disease. Exposure to second-hand smoke is especially risky for children and babies, and increases the

    risk of sudden infant death syndrome (SIDS), bronchitis, pneumonia and asthma.

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    EFFECTS OF SMOKING

    Smoking harms nearly every organ in the body, including the heart, blood vessels, lungs, eyes,

    mouth, reproductive organs, bones, bladder, and digestive organs. This article focuses on how

    smoking affects the heart and blood vessels.

    HEART DISEASE - Smoking damages the heart and blood vessels

    The heart relies on a generous supply of oxygen and nutrients from

    the two coronary arteries and their branches. Over the years, fatty

    deposits (called plaque or atheroma) can build up inside one or more

    of the coronary arteries (a process called atherosclerosis). This

    narrowing of the arteries reduces the flow of blood to the heart and

    increases the risk of heart

    attack. Smoking speeds up the

    clogging and narrowing of

    coronary arteries.

    A heart attack occurs when ablood clot forms at a narrowed

    point in a coronary artery and suddenly blocks the flow of

    blood to the heart. If the artery remains blocked, the lack of

    blood supply permanently damages the area of heart muscle

    supplied by that artery. The severity of the heart attack

    depends on how much heart muscle is permanently damaged.

    Smoking also speeds up atherosclerosis and damages other

    blood vessels. This peripheral arterial disease can reduce blood circulation, particularly to your

    hands and feet, and result in blood clots, gangrene and even amputation.

    CANCERSmoking causes the majority of lung cancers both in

    smokers and in people exposed to secondhand smoke.

    How smoking causes lung cancer

    Tobacco smoke contains more than 60 different toxic

    substances, which can lead to the development of cancer.

    Smoking causes lung cancer by damaging the cells that line

    the lungs. When you inhale cigarette smoke, which is full ofcancer-causing substances (carcinogens), changes in the

    lung tissue begin almost immediately. At first your body

    may be able to repair this damage. But with each repeated

    exposure, normal cells that line your lungs are increasingly damaged. Over time, the damage causes

    cells to act abnormally and eventually cancer may develop. Besides lung cancer, tobacco use also

    increases the risk for cancers of the mouth, lips, nasal cavity (nose) and sinuses, larynx (voice box),

    pharynx (throat), esophagus (swallowing tube), stomach, pancreas, kidney, bladder, uterus, cervix,

    colon/rectum, ovary (mucinous), and acute myeloid leukemia.

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    BRONCHITIS

    Chronic bronchitis is an inflammation of the lining of

    the bronchial tubes, the airways that connect the

    trachea (windpipe) to the lungs. This delicate, mucus-

    producing lining covers and protects the respiratory

    system, the organs and tissues involved in breathing.

    When a person has bronchitis, it may be harder for airto pass in and out of the lungs, the tissues become

    irritated, and more mucus is produced. The most

    common symptom of bronchitis is a cough.

    Cigarette smoke contains many chemicals that

    interfere with the body's method of filtering air and

    cleaning out the lungs. The smoke irritates the lungs

    and leads to overproduction of mucus. It also paralyses the cilia - tiny hair-like structures that line

    the airways and clean out dust and dirt. Paralysis of the cilia means mucus and toxic substances

    accumulate, resulting in congestion of the lungs. This extra mucus means smokers are more likely

    to suffer from chronic bronchitisand what is known as 'smoker's cough'.

    EMPHYSEMA

    In emphysema, there is a slightly different

    problem developing in the lungs as the walls

    between the tiny grape-shaped air sacs or alveoli

    are damaged and break down. They then form

    into much larger airspaces and there are fewer

    surfaces for gas exchange, so oxygen intake is less

    and the person feels breathless.Long term exposure of the lungs to the irritants in

    tobacco smoke destroys the normal lung

    structure. The elastic walls of the small airways

    within the lungs are broken down. This reduces

    the amount of lung tissue available for the

    transfer of oxygen from the air to the blood. This

    condition is called emphysema. Some degree of emphysema is found in almost all people who are

    long-term smokers, however the severity will vary depending on the amount of cigarettes smoked,

    and the number of years the individual smokes.

    Damage to the lung tissue is irreversible. Emphysema can be prevented by not smoking, avoidinganything that will irritate the lungs such as dust and cold air, and ensuring any chest infections such

    as flu and bronchitis are treated properly.

    SHALYN

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