Tobacco - Inside the Body

©Photographs courtesy of Manchester University Pathology Department

Human female chromosome map (XX). Alcohol and nicotine addiction may be in the genes

There is accumulation of carbon (smoke) within the walls of these air sacs in the lungs. This

makes the air sacs inelastic and it is difficult for air to get out of the lungs

(Emphysema)

Clubbing of the fingers is a common condition which may indicate cancers, liver diseases and

lung disease

Clubbed fingers - a sign of heart disease

Focal dust emphysema is commonest in cigarette smokers and coal miners.The black colour in this lung is due to cigarette smoke

Cells lining the bronchus- here there are no microscopic hairs needed to move dirt and dust out of the lungs- they have been destroyed by

the nicotine

Cells lining the wind pipes, the large nuclei are in cancer cells spreading through the lungs

Lung tissue blackened by smoke and showing large spaces that cause emphysema

Emphysema- these large spaces are due to the breakdown of the air sacs in the lungs

Lungs: The picture on the left is of emphysema (large air sacs) and the picture on the right is of normal lung – the picture on the left was came

from a smoker.

The air sacs in the centre of the lung tissue in the picture have broken down. The black dots are smoke particles lodged in the tissues- this

condition is emphysema. (28)

Cancer of the bronchus that has spread into the lungs

A blue colouration occurs when blood circulation is poor such as heart failure and circulation

damaged caused by cigarettes

Most amputations in the United

Kingdom are a direct result of

smoking

This man is a heavy smoker (see nicotine stained fingers) and has led to vascular disease which

has resulted in a blood clot on one of his fingers on his right hand

Damaged toes due to poor blood circulation- will lead to amputation

Amputated fingers- a result of damage to blood vessels due to smoking

Franks sign - an ear lobe crease thought to be indicative of heart problems, a possible sign of a

smoking related disease

Franks sign- ear lobe creasea sign of heart disease

Fluid collecting in the tissues, note the dent where somebody has pressed on top of the hand- a sign of heart failure – probable cause - smoking

Heart:This slice is also through the heart (compare it to the next slide) The left side is

towards the right of the image as you look at it, and shows a white area of in the heart wall. This

is tissue, which has died due to lack of blood supply

Heart: The left ventricle is towards the left of the screen, and shows enormous thickening of the wall, particularly in relation to the small cavity.

The heart is almost twice the size it should be, as it has had to work much harder than normal.

Expansion of finger ends- associated with chronic breathing and heart problems, again problems

associated with smoking

Expansion of finger ends- associated with chronic breathing and heart problems

Cancer of oesophagus- this is where the oesophagus meets the stomach

Cancer of the kidney- the cancer growth is the white tissue

Bladder cancer - the bladder is a hollow bag for storing urine- here it is cut open showing a large

cancerous growth inside

Cancer of the pancreas

Stomach ulcers (dark brown) - alcohol and smoking are factors

Stomach ulcers (dark brown)- alcohol and smoking are factors. The stomach is cut open.