Tickler Neonatology

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  • ESSENTIAL NEWBORN CARE (ENC) / UNANG YAKAP 1. Immediate drying 2. Uninterrupted skin-to-skin contact 3. Proper cord clamping and cutting 4. Non-separation of the newborn from the mother for early breastfeeding

    initiation and rooming-in

    IMMEDIATE NEWBORN CARE Call out time of birth. Deliver the baby prone on the mothers abdomen. Dry the newborn thoroughly for a full 30 seconds. Remove wet cloth. Check breathing while drying. Position newborn prone on the mothers abdomen in skin-to-skin contact.

    Cover the back with a dry blanket. o If this is not possible, place newborn in a warm, safe place close to the

    mother. Exclude second baby Remove first set of glove. Clamp and cut the cord after cord stops pulsating (1-3 minutes) for pre-

    transfusion and lesser chance of anemia and intraventricular hemorrhage. Maintain skin-to-skin contact; do not separate baby from the mother until a

    full breastfeed is achieved; watch for feeding cues. Place identification band on ankle.

    CLASSIFICATION OF NEONATAL SEPSIS EARLY ONSET LATE ONSET LATE, LATE ONSET

    Time of Onset Birth to 7 days usually 30 days

    Intrapartum complication

    Often present Usually absent Usually absent

    Transmission Vertical: maternal genital

    tract

    Vertical: Postnatal

    environment

    Environment/ community

    Clinical Manifestations

    Fulminant course, multisystem involvement, pneumonia (common)

    Insidious, focal infection, meningitis (common)

    Multisystem or focal

    Prematurity is the most important neonatal factor predisposing to infection

    NEONATAL JAUNDICE

    Indirect Hyperbilrubinemia: Yellowish Direct Hyperbilirubinemia: Greenish

    PHYSIOLOGIC JAUNDICE PATHOLOGIC JAUNDICE Onset 24 HOL usually on the

    3rd day of life TSB increasing less than 5

    mg/kg/day Decline to adult levels by the

    10th to 12th day of life

    Early onset < 24 HOL TSB increasing more than 5

    mg/kg/day TSB concentration exceeding

    12.9 mg/dL (FT) and >15 mg/dL (PT)

    DSB > 2 mg/dL or 20% of TSB (total serum bilirubin)

    Persists > 1 wk (FT) or >2 wks (PT)

    BREASTFEEDING JAUNDICE BREASTMILK JAUNDICE

    Occurs in the first week of life Starvation jaundice Can be prevented by frequent

    breastfeeding

    Occurs beyond the first week of life until the 3rd week of life

    Extension of physiologic jaundice Enhanced enterohepatic

    absorption of UCB of unidentified factors in human milk which inhibits hepatic glucoronosyl transferase

    -glucoronidase converts back conjugated bilirubin to unconjugated bilirubin

    NEONATAL COLD INJURY SIGNS AND SYMPTOMS: Apathy Refusal to eat Oliguria Coldness to touch Edema Redness of the extremities Temperature between 29.5-35 C Bradycardia, apnea, hypoglycemia, acidosis and massive pulmonary

    hemorrhage TREATMENT OF NEONATAL COLD INJURY Warming

    o Warm, ironed blanket o For premature babies, you can put a cap on the head since the head

    has the highest surface area (especially important for low birth weight and SGA babies)

    o Thermoregulated bed sheet o Radiant warmer

    Correction of metabolic disturbances

    HYPOGLYCEMIA Definition: Blood sugar of

  • NEONATAL PNEUMONIA

    Route of Transmission Ascending infection Aspiration of infected material during passage through the birth canal Predisposing factor: Prolonged rupture of membranes Causative Agents: Group B Streptococci (major pathogen producing pneumonia for developed country) E. Coli (major organism in the Philippines) Listeria spp.. Klebsiella spp. Enterococcus spp.

    Clinical Course: Sign of respiratory distress: Tachypnea, Retractions, Cyanosis Non-specific signs: Apneic spells, Thermal instability, Jaundice

    Xray: Streaky densities Confluent opacified areas Diffusely granular appearance with air bronchogram

    Treatment: Penicillin/ ampicillin and aminoglycosides Late onset (occurs more than 3 days of life)

    o Staphylococcus: Oxacillin / Vancomycin o Chlamydia: Erythromycin o Fungi: Amphotericin B

    Duration of treatment: 10 days

    TRANSIENT TACHYPNEA OF THE NEWBORN

    Follow an uneventful delivery at or near term Major presenting symptom: persistently high RR Other symptoms:

    o Mild cyanosis o Minimal respiratory distress

    Due to delayed resorption of fetal lung fluid Increased risk in cesarean delivery X-ray:

    o Central perihilar streaking o Hyperaeration o Fluid in the minor fissure

    Self- limited course Resolves within 6- 8 hours mostly May last for 72 hours Minimal O2 support usually enough Antibiotics not needed

    MECONIUM ASPIRATION SYNDROME

    Meconium: The first intestinal discharge from newborns; a viscous, dark green substance composed of intestinal epithelial cells, lanugo, mucus, and intestinal secretions, such as bile

    Meconium aspiration induces hypoxia via 3 major pulmonary effects:

    o Airway obstruction o Surfactant dysfunction o Chemical pneumonitis

    Risk Factors Post-Term delivery SGA neonates Ante-intrapartum distress and hypoxia Maternal complications causing impaired uteroplacental blood flow Eg. Hypertension Intrapartum conditions causing impaired uteroplacental blood flow Eg. cord compression

    Management Vigorous infants at birth: No required treatment Depressed/non-vigorous infants: Direct endotracheal suctioning Pulmonary toilet (remove all meconium) Supplemental oxygen Antibiotic coverage Mechanical ventilation Surfactant Inhaled nitric oxide Extracorporeal membrane oxygenation (ECMO)