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1 Hemodynamic Disorders Hemodynamic Disorders Thrombosis and Shock Thrombosis and Shock

Thrombosis and Shockmedsci.indiana.edu/c602web/602/c602web/docs/hemo_dyn/hemodyn_slides.pdfPulmonary Edema Anasarca Hydrothorax Hydropericardium Cerebral Edema. 4 Petechiae Purpura

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Page 1: Thrombosis and Shockmedsci.indiana.edu/c602web/602/c602web/docs/hemo_dyn/hemodyn_slides.pdfPulmonary Edema Anasarca Hydrothorax Hydropericardium Cerebral Edema. 4 Petechiae Purpura

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Hemodynamic DisordersHemodynamic Disorders

Thrombosis and ShockThrombosis and Shock

Page 2: Thrombosis and Shockmedsci.indiana.edu/c602web/602/c602web/docs/hemo_dyn/hemodyn_slides.pdfPulmonary Edema Anasarca Hydrothorax Hydropericardium Cerebral Edema. 4 Petechiae Purpura

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Page 3: Thrombosis and Shockmedsci.indiana.edu/c602web/602/c602web/docs/hemo_dyn/hemodyn_slides.pdfPulmonary Edema Anasarca Hydrothorax Hydropericardium Cerebral Edema. 4 Petechiae Purpura

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Pulmonary EdemaPulmonary Edema AnasarcaAnasarca

HydrothoraxHydrothorax

HydropericardiumHydropericardium Cerebral EdemaCerebral Edema

Page 4: Thrombosis and Shockmedsci.indiana.edu/c602web/602/c602web/docs/hemo_dyn/hemodyn_slides.pdfPulmonary Edema Anasarca Hydrothorax Hydropericardium Cerebral Edema. 4 Petechiae Purpura

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PetechiaePetechiae PurpuraPurpura

HemarthrosisHemarthrosisHematomaHematoma

Page 5: Thrombosis and Shockmedsci.indiana.edu/c602web/602/c602web/docs/hemo_dyn/hemodyn_slides.pdfPulmonary Edema Anasarca Hydrothorax Hydropericardium Cerebral Edema. 4 Petechiae Purpura

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HemopericardiumHemopericardium

PT and PTTPT and PTT

Page 6: Thrombosis and Shockmedsci.indiana.edu/c602web/602/c602web/docs/hemo_dyn/hemodyn_slides.pdfPulmonary Edema Anasarca Hydrothorax Hydropericardium Cerebral Edema. 4 Petechiae Purpura

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ThrombosisThrombosis

Page 7: Thrombosis and Shockmedsci.indiana.edu/c602web/602/c602web/docs/hemo_dyn/hemodyn_slides.pdfPulmonary Edema Anasarca Hydrothorax Hydropericardium Cerebral Edema. 4 Petechiae Purpura

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Lines of ZahnLines of Zahn Mural ThrombusMural Thrombus

Page 8: Thrombosis and Shockmedsci.indiana.edu/c602web/602/c602web/docs/hemo_dyn/hemodyn_slides.pdfPulmonary Edema Anasarca Hydrothorax Hydropericardium Cerebral Edema. 4 Petechiae Purpura

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Ultrasound visualizationUltrasound visualization

NoninvasiveNoninvasive Follow the patientFollow the patient High predictive valueHigh predictive valueg pg p Show meShow me..

Amniotic Fluid Amniotic Fluid EmbolizationEmbolization (Mom’s lung)(Mom’s lung)

Douglas (WrongDouglas (Wrong--Way) CorriganWay) CorriganParadoxical EmbolusParadoxical Embolus

Starts on the right, Starts on the right, ends up on the left.ends up on the left.

How?How? Patent foramen ovalePatent foramen ovale

1010--15% by ultra sound15% by ultra sound 27% at autopsy27% at autopsy About 1% big enoughAbout 1% big enough

Page 9: Thrombosis and Shockmedsci.indiana.edu/c602web/602/c602web/docs/hemo_dyn/hemodyn_slides.pdfPulmonary Edema Anasarca Hydrothorax Hydropericardium Cerebral Edema. 4 Petechiae Purpura

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Disseminated Intravascular CoagulationDisseminated Intravascular Coagulation

Hemorrhagic InfarctHemorrhagic Infarct

Page 10: Thrombosis and Shockmedsci.indiana.edu/c602web/602/c602web/docs/hemo_dyn/hemodyn_slides.pdfPulmonary Edema Anasarca Hydrothorax Hydropericardium Cerebral Edema. 4 Petechiae Purpura

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Shock is not SurpriseShock is not Surprise

Tissue hypoxia and acidosisTissue hypoxia and acidosis The PThe P33 SyndromeSyndrome

Really (pi..)Really (pi..)PP PoorPoor

PerfusionPerfusion

Many causesMany causes Complication of somethingComplication of something

Blood PressureBlood Pressure

Things start when Things start when systolic drops systolic drops below about 90 below about 90 mmHgmmHg

Heart’s pumping Heart’s pumping capacitycapacity

Blood volumeBlood volume Container sizeContainer size AutocatalyticAutocatalytic

The Shock SpiralThe Shock Spiral EndotoxicEndotoxic ShockShock

The Shock SpiralThe Shock Spiral

Page 11: Thrombosis and Shockmedsci.indiana.edu/c602web/602/c602web/docs/hemo_dyn/hemodyn_slides.pdfPulmonary Edema Anasarca Hydrothorax Hydropericardium Cerebral Edema. 4 Petechiae Purpura

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