This webinar is being recorded. - NIH Common Fund NIA webinar_… · commonfund.nih.gov Slide 4. High-Risk, High-Reward Research Program High-risk, high-impact ideas

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https://commonfund.nih.gov/newinnovator

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High-Risk, High-Reward Research Program

Annual funding opportunities



High-risk, high-impact ideas



No preliminary data required



Any topic relevant to NIH mission


High-Risk, High-Reward Research ProgramChairJames M. Anderson, MD, PhDDirector, DPCPSI; Deputy Director, NIHOD, NIH

Program LeaderRavi Basavappa, PhDProgram LeaderOSC/DPCPSI/OD

MembersKristin Abraham, PhDSenior AdvisorNIDDK

Vernon Anderson, PhDProgram DirectorNIGMS

Hugh Auchincloss, MDDeputy DirectorNIAID

David Balshaw, PhDProgram DirectorNIEHS

Marie A. Bernard, MDDeputy DirectorNIA

Robert H Carter, MDDeputy DirectorNIAMS

Jennifer Collins, MRHealth SpecialistNIEHS

Christine Colvis, PhDProgram DirectorNCATS

Milton Corn, MD, FACP, FACMIDeputy Director for Research and EducationNLM

Cindy D. Davis, PhDDirectorOffice of Dietary Supplements/DPCPSI/OD

Emmeline Edwards, PhD DirectorNCCIH

Zeynep Erim, PhDActing Division DirectorNIBIB

Valerie Florance, PhDAssociate Director for Extramural ProgramsNLM

Nara Gavini, PhD, MPhil, MScChiefNINR

Raymond Jacobson, PhDChiefCSR

Flora Katz, PhDDivision DirectorFIC

Anthony Kirilusha, PhDProgram DirectorNIAMS

Susan Koester, PhDDeputy DirectorNIMH

Rajiv Kumar, PhDChiefCSR

Roger Little, PhDDeputy Division DirectorNIDA

Jaron Lockett, PhDDeputy Division DirectorNIDA

James Mack, PhDScientific Review OfficerCSR

Judy A. Mietz, PhDProgram Director and ChiefNCI

Becky Miller, PhD Health SpecialistOSC/DPCPSI/OD

Brett Miller, PhDProgram DirectorNICHD

Daniel Miller, PhDProgram DirectorNINDS

Michael MorseGrants Management AdvisorOSC/DPCPSI/OD

Ellie Murcia, MEdProgram SpecialistOSC/DPCPSI/OD

Weijia Ni, PhDChiefCSR

Srikanth Ranganathan, PhDScientific Review OfficerCSR

Diana (Dede) Rutberg, MBAChief Grants Management OfficerNIDCR

Suzanne Ryan, PhDScientific Review OfficerCSR

John Satterlee, PhD Program DirectorNIDA

Šeila Selimović, PhDProgram DirectorNIBIB

Carol Shreffler, PhDHealth Science AdministratorNIEHS

Lillian Shum, PhDDirectorNIDCR

Heidi J. Sofia, PhDProgram DirectorNHGRI

Michael A. Steinmetz, PhDActing DirectorNEI

Nathaniel Stinson, Jr., PhD, MDActing DirectorNIMHD

Edmund Talley, PhDProgram DirectorNINDS

Lyl Tomlinson, PhDAAAS FellowOSC/DPCPSI/OD

Stephanie Johnson Webb, PhDHealth Scientist AdministratorNHLBI

Tasmeen Weik, DrPH, MPHScientific Review OfficerCSR

Elizabeth L. Wilder, PhD DirectorOSC/DPCPSI/OD



Supports unusually creative early career investigators proposing innovative, high-impact research• Started in 2007• Early Stage Investigator (no NIH R01 or equivalent

grant and within 10 years of doctoral degree or clinical training)

• Commit 25% research effort• No preliminary data required• Awards of $1.5 million disbursed in first year of 5

year project period


New Innovator Award

Research Strategy Essay 10 pages:• Scientific problem, significance, and potential impact• Innovativeness of approach• How risks and challenges will be addressed• Suitability for award• Investigator’s qualifications

Budget, Animal, Human Subject Information

No detailed budget, other information brief

Letters of Collaboration Not allowed

Research Effort At least 25%

Letters of Reference Not allowed

Application – DP2

NIH Director’s New Innovator Award (DP2)Srikanth Ranganathan, PhD

Scientific Review Officer, New Innovator Award Review

Rajiv Kumar, PhD (Chief)

Musculoskeletal, Oral and Skin Sciences IRG,

CSR, NIH

2019-20 WebinarJuly 17, 2019

New Innovator Award Review Process

Appl

Receipt: Late-August

Two Stage Review Process

Stage 1 Mail Review

Finalists Selection via Prelim Scores and Stage 2 Editorial Panel Members

Stage 2 Editorial Panel Meeting

Council of Councils: MayPublic Announcement of

Awards: ~September

Selection of Awardees by OD / ICs

All applications are assigned to one panel (Integrated Review Group) – Musculoskeletal, Oral, and Skin Sciences IRG

Administrative Review: Check for completeness and ESI eligibility

Applications are grouped based on science areas identified by applicant

Enter conflicts from application: Institutional / Collaborative

Recruit mail reviewers to cover all major science areas

Peer-Review Process – Pre-Stage 1

Peer-Review Process: Stage 1 (Mail Reviews)

Panel of Mail Reviewers

Match reviewers with science in the application

3 Reviewers / Application

Three Criteria and an Overall Impact Score (1-9)

“Importance and Potential Impact of the Scientific Problem” “Novelty / Innovativeness of Approach” “Creative Potential of ESI”

Overall Impact Paragraph

Stage 2: Selection of Finalists

Rank order the Mail reviewers’ Overall Impact Scores

An unbiased selection of applications by the editorial panelists from the applications (based on overall impact scores and the critiques)

About 20% of applications selected for Stage 2

Stage 2: Editorial Review

26-27 panelists who are senior members and

experts with broad scientific understanding

Each application assigned to 3 discussants and all

applications are discussed

Scoring is focused on Impact & Innovation

Provide impact statement and impact score

Release of Final scores and Summary statements

Discussed statements: 2nd stage impact statements

with resume and summary of discussion

Non-discussed statements: 1st stage critiques

Questions about the Review process

Contact:

Srikanth Ranganathan (SRO, MOSS IRG)301-435-1787; [email protected]

Rajiv Kumar (CHIEF, MOSS IRG)301-435-1212; [email protected]

mailto:[email protected]

mailto:[email protected]




Eligibility




Application & Submission




Budget




Review

Documents

This webinar is being recorded. - NIH Common Fund NIA webinar_… · commonfund.nih.gov Slide 4. High-Risk, High-Reward Research Program High-risk, high-impact ideas