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Page 1: This program is endorsed by Aix-Marseille UniversityThis program is endorsed by Aix-Marseille University ... Abstract Presentation The abstracts accepted for oral or poster presentation
Page 2: This program is endorsed by Aix-Marseille UniversityThis program is endorsed by Aix-Marseille University ... Abstract Presentation The abstracts accepted for oral or poster presentation

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The Organizing Committee of ECAS 2019 and the Board of ECAS wish to thank the companies supporting our Congress with an educational grant

G O L D S P O N S O R

P L A T I N U M S P O N S O R

S I L V E R S P O N S O R

This program is endorsed by Aix-Marseille University

LA BIOSTHETIQUE®

Page 3: This program is endorsed by Aix-Marseille UniversityThis program is endorsed by Aix-Marseille University ... Abstract Presentation The abstracts accepted for oral or poster presentation

Dear Colleagues,

This is an invitation to join us at the Fifteenth Annual Scientific Congress of the European CardiacArrhythmia Society “ECAS 2019” to be held in Marseille, France June 16 to 18, 2019 at the Palais duPharo, Eugenie Congress Center. All those who attended previous editions of ECAS Congress know thatit is a highly scientific and educational event in a cheerful atmosphere which facilitates interactionbetween the renowned Faculty and the audience which is particularly appreciated by fellows. Thisedition promises to be successful and we will be delighted to have you among us in Marseille next June

EXECUTIVE COMMITTEE OF THE EUROPEAN CARDIAC ARRHYTHMIA SOCIETYPresident Riccardo Cappato (Milan, IT)

Past President Wyn Davies (London, GB)Vice-President (Education & Research) Richard Hauer (Utrecht, NL)

Vice-President (National Societies) Massimo Santini (Rome, IT)Vice-President (International Societies & EU) Samuel Lévy (Marseille, FR)

Treasurer Eli Ovsyshcher (Beersheba, IL)Secretary General Leo Van Wersch (Paris, FR)

Continuing Medical Education Nicholas Peters (London, GB)Chair Membership Program Stefan Kääb (Munich, DE)Organizing annual Congress Neil Sulke (Eastbourne, GB)

Education Committee Gerhard Steinbeck (Munich, DE)

Prof. Riccardo Cappato, MD President of ECAS

Prof. Samuel Lévy, MD Congress Chairman

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Organizing Committee ECAS 2019Leonardo Calò, Riccardo Cappato, Wyn Davies, Fernand Hessel, Ellen Hoffmann, Stefan Kääb, GillesLascault, Samuel Lévy (Chair), Gerhard Steinbeck

Riccardo Cappato, MD Samuel Lévy, MD

Dobromir Dobrev, MDGerhard Steinbeck, MD Stefan Kaab, MD Leonardo Calo, MD

Page 4: This program is endorsed by Aix-Marseille UniversityThis program is endorsed by Aix-Marseille University ... Abstract Presentation The abstracts accepted for oral or poster presentation

Masood Akhtar (Milwaukee, USA)Etienne Aliot (Nancy, FR)Maurits A. Allessie (Maastricht, NL)Eckhard Alt (Munich, DE)Charles Antzelevitch (Utica, USA)Andrey Ardashev (Moscow, RU)Serge S. Barold (Boca Raton, USA)David Benditt (Minneapolis, USA)Poul Erik Bloch-Thomsen (Hellerup, DK)Jozsef Borbola (Budapest, HU)Johannes Brachmann (Coburg, DE)A John Camm (London, GB)Alessandro Capucci (Ancona, IT)Riccardo Cappato (Milan, IT)David S. Cannom (Los Angeles, USA)Sumeet Chugh (Los Angeles, USA)Antonio Curnis (Brescia, IT)Philippe Coumel*(Paris, FR)D. Wyn Davies (London, GB)Hu Dayi (Beijing, CN)Luc De Roy (Yvoir, BE)Dobromir Dobrev (Essen, DE)Sergio Dubner (Buenos Aires, AR)Nils G. Edvardsson (Göteborg, SE)Michaël Eldar (Tel Aviv, IL)Nabil El-Sherif (New York, USA)Jerónimo Farré (Madrid, ES)John Fisher (New-York, USA)Guy Fontaine (Paris, FR)*Robert Frank (Paris, FR)

Seymour Furman* (New-York, USA)Richard Hauer (Utrecht, NL)Habib Haouala (Tunis, TN)Yoshito Iesaka (Tokyo, JP)Michiel Janse (Amsterdam, NL)Charles Jazra (Beirut, LB)Xavier Jouven (Paris, FR)Werner Jung (Villingen, DE)Stefan Kääb (Munich, DE)Prapa Kanagaratnam (London, GB)Joergen Kanters (Copenhagen, DK)Bondo Kobulia (Tbilisi, GE)Karl-Heinz Kuck (Hamburg, DE)Jean-Yves Le Heuzey (Paris, FR)Samuel Lévy (Marseille, FR)Berndt Lüderitz (Bonn, DE)Marek Malik (London, GB)Harry G. Mond (Melbourne, AU)Alessandro A Montenero (Rome, IT)Conception Moro Serrano (Madrid, ES)Arthur J. Moss (Rochester, NY, USA)Michael Näbauer (Munich, DE)Gerald V. Naccarelli (Hershey, USA)Yuji Nakazato (Tokyo, JP)Andrea Natale (Cleveland, USA)Promund I. W. Obel (Johannesburg, ZA)Brian Olshansky (Iowa City, USA)Bertil S. Olsson (Lund, SE)Oscar Oseroff (Buenos Aires, AR)Ali Oto (Ankara, TR)

Eli Ovsyshcher (Beersheba, IL)Douglas L. Packer (Rochester, USA)Luigi Padeletti*Nicholas S Peters, (London, GB)Dubravko Petrač (Zagreb, HR)Eric N. Prystowsky (Indianapolis, USA)Antonio Raviele(Venice, IT)Amiran Revishvili (Moskow, RU)Dwight Reynolds (Oklahoma, USA)Edward Rowland (London, GB)Sanjeev Saksena (New Brunswick, USA)Luca Santini (Rome, IT)Massimo Santini (Rome, IT)Maurizio Santomauro (Naples, IT)Dipen Shah (Geneva, CH)Richard Schilling (London, GB)Georg Schmidt (Munich, DE)Jabir Sra (Milwaukee, USA)Gerhard Steinbeck (Munich, DE)Neil Sulke (Eastbourne, GB)Paul Touboul (Lyon, FR)Albert Waldo (Cleveland, USA)Hein JJ Wellens (Maastricht, NL)Bruce Wilkoff (Cleveland, USA)David Wilber (Chicago, USA)George D. Wyse (Calgary, CA)

*In memoriam

Scientific Advisory Board

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Noel Boyle; Johannes Brachmann; Hugh Calkins; Leonardo Calò; John Camm; David Cannom; Alessandro Capucci; Antony Chu;

Roberto De Ponti; Luigi Di Biase; Dobromir Dobrev; Mark Estes; Richard Hauer; Ellen Hoffmann; Michiel Janse; Helmut Klein; Pier

Lambiase; Thorsten Lewalter; Michael Näbauer; Promund Obel; Brian Olshansky; Eli Ovsyshcher; Jeanne Poole; Sanjeev Saksena;

Walid Saliba; Lucas Santini; Massimo Santini; Dipen Shah; Gerhard Steinbeck; Jacob Tfelt-Hansen; Niraj Varma; Reza Wakili; Albert

Waldo; David Wilber; Bruce Wilkoff.

Abstract Selection

Each abstract has been sent to 6 reviewers and been evaluated by a minimum of 4 of them.The Organizing Committee would like to thank the abstract reviewers for their valuable help in abstract selectionfor the ECAS 2019 program:

Abstract Presentation

The abstracts accepted for oral or poster presentation will be published in a supplement issue of the Journal ofInterventional Cardiac Electrophysiology (JICE), the official journal of ECAS provided the authors attend the congressand present their work.The oral presentation of abstracts is 10 minutes plus 5 minutes for discussion.All posters accepted for presentation will be chaired. Please to check the day and time at which your poster will be presentedto the chairpersons and the time at which the presenters should be near their poster board.

Alawi Alsheikh-Ali; Elad Anter; Charles Antzelevitch; Andrey Ardashev; Adrian Baranchuk; Serge Barold; Antonio Bayes De Luna;David Benditt; Leonardo Calò; David S Cannom; Riccardo Cappato; Wyn Davies; Roberto De Ponti; Luigi Di Biase; Mark Estes III; HeidiEstner; Jerónimo Farré; John Fisher; Richard Hauer; Ellen Hoffmann; Wael Jaber; Warren Jackman; Charles Jazra; Xavier Jouven; StefanKääb; Helmut Klein; Gilles Lascault; Jean-Yves Le Heuzey; Samuel Lévy; Thorsten Lewalter; Bruce Lindsay; Shaowen Liu; Peter Loh;Pierpaolo Lupo; Michael Näbauer; Yuji Nakazato; Andrea Natale; Petr Neuzil; Eli Ovsyshcher; Ali Oto; Douglas L Packer; Luigi Padeletti*;Nicholas S. Peters; Dubravko Petrač; Antonio Raviele; Edward Rowland; Sanjeev Saksena; Massimo Santini; Richard Schilling; JasbirSra; Gerhard Steinbeck; Neil Sulke; Ernst Vester; Reza Wakili; Albert Waldo; Bruce Wilkoff.*In memoriam

Program Committee

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Abstract Awards

Publication

Sanjeev Saksena, MDJICE founding Editor-in-Chief

Leonardo Calo, MD ECAS JICE co-Editor

Andrea Natale, MD JICE Editor-in-Chief

Presentation of the Awards for the Best Oral Abstracts will take place during the Opening Ceremony on Sunday June 16, 2019 in Room La Majorstarting at 5:30PM.

Presentation of the Awards for Best Poster Presentations will take place onTuesday June 18, 2019 12:00 PM-12:30 PM.Room Grand Large

JICE(Journal of Interventional Cardiac Electrophysiology)

is the official Journal of the European Cardiac Arrhythmia Society

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General information

Congress venuePalais du Pharo – Eugenie Congress Center58 Boulevard Charles Livon - 13007 MarseilleTel : +33 (0) 4 91 14 64 95www.palaisdupharo.marseille.fr/

Badges Badges and Final Program will be available for pre-registeredparticipants and Faculty at the ECAS Welcome Desk, Palais duPharo, Marseille, starting Saturday June 15, 2019 from 2:00 PMto 5:00 PM.

ECAS Congress SecretariatJosette Razafimbelo

Tel: + 33 (0)4 89 98 98 08Cell: +336 26 07 55 74E-mail: [email protected]

RegistrationRegistration and payment of Congress fees as well as paymentof Membership dues can be done through the website.Registration on site will start on Sunday June 16, 2019 from 7:30AM to 5:00 PM at Palais du Pharo.

CurrencyPayment in cash for registration on site must be made in eurosonly. Payment using Visa credit cards will be accepted on theCongress site. Personal checks cannot be accepted.

Congress WebsiteAll information, Scientific Program and Registration to thecongress, Abstract submission and Membership subscriptionwith secured payment can be done through our website

http://www.ecas-heartrhythm.org

Scientific ProgramThe Program includes pre-arranged sessions and workshops ordebates. It can be downloaded from our website as well as theProgram of Abstracts selected for oral or poster presentations.The time allotted to Faculty presentation is 22 minutes includingdiscussion when the session includes 4 speakers and 18minutes including discussion in the 5 speaker sessions.

Insurance The Organizing Committee of ECAS cannot accept liabilityrelated to injuries or loss or damage of property belonging tocongress participants and accompanying persons either duringor occurring after the congress.

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PROGRAM AT A GLANCE ECAS 2019

SUNDAY JUNE 16, 2019

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PROGRAM AT A GLANCE ECAS 2019

MONDAY JUNE 17, 2019

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Conference Rooms

PROGRAM AT A GLANCE ECAS 2019

TUESDAY JUNE 18, 2019

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GROUND FLOOR

FIRST FLOOR SECOND FLOOR

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SUNDAY JUNE 16, 2019

SUNDAY JUNE 16, 2019 8:30 AM - 10:00 AMROOM GRAND LARGEWorkshop WS-01

Atrial fibrillation ablation in 2020Chairpersons: Douglas Packer (Rochester, USA), Mahmoud Suleiman (Haifa, IL)

1. Is there a mortality benefit with AF ablation in CABANA : Impact of normal sinus rhythmDouglas Packer (Rochester, USA)

2. Dealing with CHF with AF : Biventricular pacing or AF ablation Hugh Calkins (Baltimore, USA)

3. Revisiting mode of AF ablation : linear and rotor ablationDavid Wilber (Chicago, USA)

4. AF ablation – endpoint of AF ablation : 30 sec vs monitoringJeanne Poole (Seattle, USA)

SUNDAY JUNE 16, 2019 8:30 AM - 10:00 AMROOM ESTAQUEWorkshop WS-02

Prevention and management of device infectionsChairpersons: Bruce Wilkoff (Cleveland, USA); Christoph Starck (Berlin, DE)

1. Pathophysiology and bacteriology of CIED infectionsBruce Wilkoff (Cleveland, USA)

2. Impact of CIED Infections on survivalBruce Wilkoff (Cleveland, USA)

3. Prophylactic and peri procedural antibiotics before and after the PADIT trialJamil Bashir (Vancouver, CA)

4. Antibiotic envelope therapy before and after WRAP-ITCharles Kennergren (Gothenburg, SE)

Panel discussion: What is and should be the rate of CIED Infection and what are the barriers to optimal infectionprevention?

SUNDAY JUNE 16, 2019 8:30 AM - 10:00 AMROOM JOLIETTEWorkshop WS-03

ECG pacemaker and CRT dysfunction (case studies)Chairperson: Eli Ovsyshcher (Beersheba, IL)

1. Bengt Herweg (Tampa, USA)

2. Promund Obel (Johannesburg, ZA)

3. Pugazhendhi Vijayaraman (Wilkes Barre, USA)

4. Brian Olshansky (Iowa City, USA)

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SUNDAY JUNE 16, 2019

SUNDAY JUNE 16, 2019 8:30 AM - 10:00 AM ROOM SAINT JEANWorkshop WS-04

A mandatory issue: anatomical knowledge for catheter ablation targetsChairpersons: Roger Winkle (Palo Alto, USA), Richard Schilling (London, GB)

1. AVNRT and accessory pathway ablationCarlo Lavalle (Rome, IT)

2. Mandatory knowledge for ablating atypical atrial fluttersRoger Winkle (Palo Alto, USA)

3. Atrial fibrillation ablationLuigi Di Biase (New York, USA)

4. Ventricular Tachycardia ablationRichard Schilling (London, GB)

SUNDAY JUNE 16, 2019 8:30 AM - 10:00 AMROOM MUCEMWorkshop WS-05

Syncope and tachycardias related to autonomous nervous system disturbances Chairpersons: David Benditt (Minneapolis, USA), Richard Sutton (Monaco, MC)

1. Postural orthostatic tachycardia syndrome (POTS)David Benditt (Minneapolis, USA)

2. Effect of AF on the autonomous nervous system and cognitive impairmentLena Rivard (Montreal, CA)

3. Differences between the ESC and the HRS Guidelines on syncope (2017/18)Richard Sutton (Monaco, MC)

4. Inappropriate sinus tachycardia: a diagnosis of eliminationSamuel Levy (Marseille, FR)

SUNDAY JUNE 16, 2019 8:30 AM - 10:00 AMROOM NOTRE DAMEWorkshop WS-06

Case-based presentation of EP tracings dedicated to young electrophysiologists

Chairpersons: Warren Jackman (Oklahoma City, USA), Luca Santini (Rome, IT)

1. Various clinical aspects of atrial flutterAgostino Piro (Rome, IT)

2. Tracings of arrhythmias involving the atrioventricular junction Jacopo Marazzato (Varese, IT)

3. Tracings of arrhythmias involving atrioventricular accessory pathwaysWarren Jackman (Oklahoma City, USA)

4. Tracings of ventricular arrhythmias Roland Tilz (Luebeck, DE)

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SUNDAY JUNE 16, 2019

SUNDAY JUNE 16, 20198:30 AM - 10:00 AMROOM LACYDONChaired Poster session APosters displayed from 8:30 AM to 12:00 PMPresenters and Chairpersons presents from 9:00 am to 10:30 am

MECHANISMS OF CARDIAC ARRHYTHMIASChairpersons: Ernst Vester (Dusseldorf, DE), Prapa Kanagaratnam (London, GB)

14.01 Abstract 03-13Rare variants in OBSCN gene in lone atrial fibrillation and arrhythmogenic right ventricular cardiomyopathyIrina Rudaka1, Dmitrijs Rots1, Arturs Uzars1, Linda Gailite1, Aivars Lejnieks2, Oskars Kalejs3

1Riga Stradins University, Riga, Latvia, 2Riga East Clinical University Hospital, Riga, Latvia, 3Pauls Stradins ClinicalUniversity Hospital , Riga, Latvia

14.02 Abstract 05-12Dipole density mapping of nonsustained supraventricular tachycardia - a case reportJunaid Zaman1, Michael Rochon-Duck2, Michael Paikal2, Ashkan Ehdaie2, Graydon Beatty3, Michael Shehata2,Xunzhang Wang2

1Royal Brompton Hospital, London, United Kingdom, 2Cedars Sinai Medical Center, Los Angeles, United States,3Acutus Medical, Carlsbad, United States

14.03 Abstract 07-10Prognostic value of new-onset right bundle-branch block in acute myocardial infarction patients: fromMIRAMI registryMarouane Mahjoub1, Mehdi Boussada1, Mejdi Ben Messaoud1, Fedoua Omri1, Ayoub Belfkih1, Selma Messous1,Nidhal Bouchahda1, Majed Hassine1, Zohra Dridi1, Fethi Betbout1, Habib Gamra1

1Cardiology department A: Fattouma Bourguiba University Hospital, Monastir, Monastir, Tunisie

14.04 Abstract 07-15Risk stratification during during left atrial ablation with ASD closure device protrusionJunaid Zaman1, Steven Burstein1, Charles Pollick1, Anil Bhandari1, Ivan Ho1

1Good Samaritan Hospital, Los Angeles, United States

14.05 Abstract 07-18Postablative pericarditis in a patient with a prior history of rheumatic disease: a case reportEvgeny Zhelyakov1, Andrey Ardashev1, Armen Kocharyan1

1Moscow State University, Moscow, Russia

Supraventricular Tachycardia

14.06 Abstract 12-10Diagnostic mechanism of supraventricular tachycardias: value of different electrophysiological maneuversMarouane Mahjoub1, Sana Ouali2, Manel Ben halima2, Mejdi Ben Messaoud1, Mehdi Boussada1, Nidhal Bouchahda1,Majed Hassine1, Zohra Dridi1, Fethi Betbout1, Habib Gamra1, Sami Mourali21Cardiology department A: Fattouma Bourguiba University Hospital, Monastir, , Monastir, Tunisia, 22- Cardiologydepartment University Hospital La Rabta Tunis, Tunis, Tunisia

14.07 Abstract 10-10Prognostic value of serum brain natriuretic peptide and troponin as predictors of short-term outcomesin patients presenting with syncope to the emergency departmentGuillermo Mora1, Fabio Sierra2

1Universidad Nacional de Colombia, Bogota, Colombia, 2Fundacion Universitaria Ciencias de la Salud, Bogota,Colombia

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SUNDAY JUNE 16, 2019

14.08 Abstract 07-11Right bundle branch block and S1Q3-type patterns for risk stratification in acute pulmonary embolismMarouane Mahjoub1, Nadia Ben Brahim1, Ayoub Belfkih1, Mejdi Ben Messaoud1, Nidhal Bouchahda1, Selma Messous1,Majed Hassine1, Zohra Dridi1, Fethi Betbout1, Mourad Gahbiche2, Habib Gamra1

1Cardiology department A: Fattouma Bourguiba University Hospital, Monastir, Monastir, Tunisie, 2AnesthesiolgyDepartment Fattouma Bourguiba Hospital, Monastir, Tunisie

SUNDAY JUNE 16, 201910:30 AM - 12:00 PMROOM GRAND LARGEAbstract Oral session 1

Basic science and mechanism of cardiac arrhythmiasChairpersons: Michiel Janse (Amsterdam, NL), Andre Kleber (Boston, USA)

01.1 Abstract 01-17In-utero exposure to nicotine alter the postnatal development of the cardiac sodium channel in rabbitMichael Biet1, Anh Tuan Ton2, Robert Dumaine1

1Université de Sherbrooke, Sherbrooke, Canada, 2Université de Montréal, Montréal, Canada

01.2 Abstract 01-13Repolarisation modifications in an in vitro model produce recognisable changes in the contactelectrogram morphologyAlec Saunders1, Konstantinos-Nektarios Tzortzis1, Balvinder Handa1, Chris D. Cantwell1, Fu Siong Ng1, Nicholas S.Peters1, Rasheda A. Chowdhury1

1ElectrocardioMaths Programme, Centre for Cardiac Engineering and National Heart and Lung Institute, ImperialCollege London, London, United Kingdom

01.3 Abstract 02-10Increased nucleoside diphosphate kinase contributes to proarrhythmic sarcoplasmic reticulum Ca2+ leakin atrial cardiomyocytesIssam Abu-Taha1, Marina Schäfer1, Ronja Kerßenboom1, Lucas Becker1, Xiao Yan Qi2, Patrice Naud2, VanessaGundlach1, Marcus Kamler3, Jordi Heijman4, Thomas Wieland5, Stanley Nattel2, Dobromir Dobrev1

1Institute of Pharmacology, West German Heart and Vascular Center, University Duisburg-Essen, Essen, Germany,2Department of Medicine, Montreal Heart Institute and Université de Montréal, Montreal, Canada, 3Department ofThoracic and Cardiovascular Surgery, West German Heart and Vascular Center Essen, University Hospital Essen,Essen, Germany, 4Department of Cardiology, CARIM School for Cardiovascular Diseases, Maastricht University,Maastricht, Netherlands, 5Institute of Experimental and Clinical Pharmacology and Toxicology, Mannheim MedicalFaculty, University of Heidelberg, Heidelberg, Germany

01.4 Abstract 01-18The role of the NLRP3 inflammasome in postoperative atrial fibrillationTina Veleva1, Na Li2, Christin Schmidt1, Issam Abu-Taha1, Marcus Kamler3, Jordi Heijman4, Xander Wehrens2, StanleyNattel5, Dobromir Dobrev1

1Institute of Pharmacology, West German Heart and Vascular Center, University Duisburg-Essen, Essen, Germany,2Cardiovascular Research Institute, Baylor College of Medicine, Houston, United States, 3Department of Thoracicand Cardiovascular Surgery, West German Heart and Vascular Center, University Duisburg-Essen, Essen, Germany,4Department of Cardiology, CARIM School of Cardiovascular Diseases, Maastricht University, Maastricht, Netherlands,5Department of Medicine, Montreal Heart Institute and Université de Montréal, Montreal, Canada

10:00 AM - 10:30 AMCoffee break in Phar Club and visit to posters Room Lacydon

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SUNDAY JUNE 16, 2019

01.5 Abstract 01-19Novel heart-specific lnc-RNAs identified by deep sequencing contribute to pathogenesis inarrhythmogenic cardiomyopathyLiang Chen1, Jiangping Song1, Shengshou Hu1

1 Fuwai hospital, Beijing, China

01.6 Abstract 01-16Diabetes mellitus-associated IL-1� causes arrhythmia through modulating mitochondria oxidative stressand sr Ca2+ releaseHong Liu1, Bum Rak Choi2, An Xie1, Tae Yun Kim2, Yang Zhao3, Guangbin Shi2, Karim Roder2, Man Liu1, DmitryTerentyev2, Samuel Dudley1

1University of Minnesota, Minneapolis, United States, 2Rhode Island Hospital, Brown University, providence, UnitedStates, 3Lanzhou University, Lanzhou, China

SUNDAY JUNE 16, 201910:30 AM - 12:00 PMROOM ESTAQUEAbstract Oral session 2

ATRIAL FIBRILLATION ABLATION ADVANCES OF TECHNIQUES AND OUTCOMEChairpersons: Douglas Packer (Rochester, USA), Jeanne Poole (Seattle, USA)

02.1 Abstract 15-26Efficacy and safety of cryoballoon ablation in patients with heart failure and reduced left ventricularejection fraction: a multicenter studyChristian-Hendrik Heeger1, Amr Abdin1, Spyridon Liosis1, Shibu Mathew2, Bruno Reissmann2, Kivanc Yalin1, ThomasFink1, Riccardo Proietti1, Charlotte Eitel 1, Julia Vogler1, Christine Lemes2, Tilman Maurer2, Andreas Rillig2, RozaMeyer-Saraei1, Tobias Graf1, Peter Wohlmuth2, Feifan Ouyang2, Karl-Heinz Kuck2, Andreas Metzner2, Roland Tilz1

1University Heart Center Lübeck, Lübeck, Germany, 2Asklepios Klinik St. Georg, Hamburg, Germany

02.2 Abstract 15-10Development, in vitro and human validation and application of a novel mapping method in guidingatrial tachycardia and atrial fibrillation ablation: arrhythmia mapping by stochastic trajectory analysisof ranked signals (star).Shohreh Honarbakhsh1, Ross J Hunter1, Waqas Ullah1, Emily Keating1, Malcolm Finlay1, Richard J Schilling1

1Barts Heart Centre, Barts Health NHS trust, London, United Kingdom

02.3 Abstract 15-17Investigating colocalization of voltage, fractionated electrograms, and dominant frequency at sites oftermination of persistent atrial fibrillation via ablationNosheen Moosvi1, Albert Rogers1, Abhinav Singh1, Mahmood Alhusseini1, Tina Baykaner1, Paul Wang1, MintuTurakhia1, Paul Clopton1, Wouter-Jan Rappel2, Sanjiv Narayan1

1Stanford University, Stanford, United States, 2UCSD Department of Physics, La Jolla, United States.

02.4 Abstract 15-11Do sites where ablation terminates persistent AF show organization?Junaid Zaman1, Mahmood Alhusseini2, Gabriela Meckler2, Nosheen Moosvi2, Albert Rogers2, Christopher Kowalewski2,David Vidmar2, Tina Baykaner2, David Krummen3, Johannes Brachmann4, Paul Wang2, John Miller5, Paul Clopton2,William Sauer6, Wouter Rappel3, Nicholas Peters1, Felipe Atienza7, Sanjiv Narayan2

1Imperial College, London, United Kingdom, 2Stanford University, Palo Alto, United States, 3University of California,San Diego, United States, 4Klinikum Coburg, Coburg, Germany, 5Indiana University, Indiana, United States, 6Universityof Colorado, Denver, United States, 7Univ Gregorio Maranon, Madrid, Spain

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SUNDAY JUNE 16, 2019

02.5 Abstract 15-25Sex differences in the outcome after pulmonary vein isolationBert Vandenberk1, Bart François1, Tim Boussy2, Ben Corteville3, Stefan Ketels4, Frank Provenier1

1Department of Cardiology, AZ Maria Middelares, Gent, Belgium, 2Department of Cardiology, AZ Groeninge, Kortrijk,Belgium, 3Department of Cardiology, AZ Jan Palfijn, Gent, Belgium, 4Department of Cardiology, AZ Damiaan,Oostende, Belgium

02.6 Abstract 18-20Efficacy of a weight based peri-procedural anticoagulation protocol for left atrial ablationChristopher Bradley1, Divyashree Varma1, Julie George1, Salim Ahmed1, David Nori1, Nathan Foster1, Hazim Al-Ameri1, Ilana Kutinsky1, K. Ching Man1, Brian Williamson1, David E. Haines1

1William Beaumont Hospital, Royal Oak, United States

SUNDAY JUNE 16, 201910:30 AM - 12:00 PMROOM JOLIETTEAbstract Oral session 3

Ablation of supraventricular tachyarrhythmiasChairpersons: Luigi Di Biase (New York, USA), Malcom Finlay (London, GB)

03.1 Abstract 18-17Machine learning successfully identifies the locations of accessory pathways from surface ECGsBen N. Cullen1, Ahran D. Arnold1, James P. Howard1, Matthew J. Shun-Shin1, Ian J. Wright1, D Wyn Davies1, PhangBoon Lim1, Michael Koa-Wing1, Norman Qureshi1, David C. Lefroy1, Fu Siong Ng1, Nicolas S. Peters1, Nick WF.Linton1, Prapa Kanagaratnam1, Darrel P. Francis1, Zachary I. Whinnett11Imperial College London, London, United Kingdom

03.2 Abstract 18-23Comparison of pacemaker pocket approach to femoral approach for atrioventricular nodal ablationNagalakshmi Nagarajan1, Manju Bengaluru Jayanna1, Amgad Mentias1, Michael Giudici11University of Iowa Hospital and Clinics, Iowa City, United States

03.3 Abstract 18-11Mid-term experience with a novel hybrid CRYO/RF focused technique in paroxysmal and persistent atrialfibrillation Michael Giudici1, Steven Bailin1

1University of Iowa Hospitals, Iowa City, United States

03.4 Abstract 18-25Modification pulmonary veins antrum in atrial fibrillation patients resulted in none severe pulmonaryvein stenosis Jian Qiang Zhang1, Rong Hui Yu2, De Yong Long2, Cai Hua Sang2, Chang Sheng Ma2, Jian Zeng Dong2

1Shanghai East Hospital, Shanghai, China, 2Beijing Anzhen Hospital, Beijing, China

03.5 Abstract 13-10Catheter ablation of right-sided accessory pathways in small children Moshe Swissa1, Einat Birk2, Tamir Dagan2, Michal Fogelman2, Tom Einbinder2, Elchanan Bruckheimer2, RamiFogelman2

1Kaplan Medical Center, Rehovot. The Hebrew University, Jerusalem, Israel, Rehovot, Israel, 2The SchneiderChildren’s Medical Center of Israel, Cardiology Institute, Petach Tiqva, Sackler School of Medicine, Tel Aviv University,Israel, Petach Tiqva, Israel

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SUNDAY JUNE 16, 2019

SUNDAY JUNE 16, 201910:30 AM - 12:00 PMROOM MUCEMAbstract Oral session 4

Focus on His bundle pacingChairpersons: Mark Estes III (Pitsburg, USA), Francesco Zanon (Rovigo, IT)

04.1 Abstract 21-10Selective vs nonselective His bundle pacing (HBP): results from the Geisinger HBP registryPugazhendhi Vijayaraman1, Dominick Beer1, Angela Naperkowski1, Faiz A Subzposh1, Parikshit S Sharma2

1Geisinger Heart Institute, Mountain Top, United States, 2Rush University, Chicago, United States

04.2 Abstract 24-10Non-invasive epicardial mapping reveals mechanisms of cardiac resynchronisation therapy via Hisbundle pacingAhran Arnold1, Matthew Shun-Shin1, Daniel Keene1, James Howard1, Ji-Jian Chow1, Kevin Leong1, Ian Wright1,Graham Cole1, SM Afzal Sohaib2, Fu Siong Ng1, Norman Qureshi1, Michael Koa-Wing1, Nick Linton1, David Lefroy1,Phang Boon Lim1, D Wyn Davies1, Amal Muthumala2, Mark Tanner1, Nicolas Peters1, Prapa Kanagaratnam1, DarrelFrancis1, Zachary Whinnett11National Heart and Lung Institute, Imperial College London, London, United Kingdom, 2St Bartholomew’s Hospital,London, United Kingdom

04.3 Abstract 22-11Pacing beyond the site of block: feasibility of left bundle branch area pacing (LBBAP)Pugazhendhi Vijayaraman1, Faiz A Subzposh1, Angela Naperkowski11Geisinger Heart Institute, Mountain Top, United States

04.4 Abstract 22-12Can His bundle pacing lead slack at implantation predict future threshold increase?Pugazhendhi Vijayaraman1, Dominick Beer1, Angela Naperkowski1, Faiz A Subzposh1

1Geisinger Heart Institute, Mountain Top, United States

04.5 Abstract 22-13Feasibility and durability of His bundle pacing: a single center experienceDivyashree Varma1, Christopher Bradley1, Ilana Kutinsky1, Hazim Al-Ameri1, David Nori1, Ching Man1, David Haines1,Brian Williamson1

1William Beaumont Hospital, Royal Oak, MI, United States

04.6 Abstract 23-17Atrial pacing or His Bundle Pacing?Grigorios Katsouras1, Luca Sgarra2, Antonio Di Monaco1, Tommaso Langialonga1, Massimo Grimaldi1, FrancescoZanon3

1F. Miulli Hospital, Acquaviva Delle Fonti, Italy, 2Santa Maria degli Angeli Hospital, Putignano, Italy, 3

Santa Maria Della Misericordia Hospital, Rovigo, Italy

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SUNDAY JUNE 16, 2019

SUNDAY JUNE 16, 20192:00 PM - 3:30 PMROOM GRAND LARGESession SP-01

12th Japan HRS-ECAS (DRAFT)Program coordinators: Samuel Levy (ECAS) and Yuji Nakazato (JHRS)

Cardiac arrhythmia ablation: Learning from difficult casesChairpersons: Kenzo Hirao (Tokyo, JP), Yuji Nakazato (Tokyo, JP)

1. Atypical flutter ablationDipen Shah (Geneva, CH)

2. Atrial fibrillation ablationKazuhiro Satomi (Tokyo, JP)

3. PVC ablationJoel Fedida (Paris, FR)

4. VT/VF ablationAkihiko Nogami (Tsukuba, JP)

SUNDAY JUNE 16, 20192:00 PM - 3:30 PMROOM ESTAQUE Session AF-01

New insights into mechanisms and pathogenesis of atrial fibrillation (AF)Chairpersons : Thomas Deering (Atlanta, USA), Reza Wakili (Essen, DE)

1. Fat and AF Stephane Hatem (Paris, FR)

2. Obstructive sleep apnea and AF ablationMahmoud Suleiman (Haïfa, IL)

3. Ventricular fibrosis and AF Fu Siong Ng (London, GB)

4. Inflammatory signaling and AF Dobromir Dobrev, (Essen, DE)

Luncheon PanelRoom EUGENIE Pharo Congress Center

12:15 pm-1:45 pm Hot topics in Cardiac ArrhythmiasChairpersons: Riccardo Cappato (Milan, IT), Richard Hauer (Utrecht, NL)

1. The basics of cardiac defibrillationAndré Kleber (Harvard University, Boston, USA)

2. Recent developments in subcutaneous ICD Implantable defibrillatorsRiccardo Cappato (Milan, IT)

3. Atrial fibrillation and diastolic Heart Failure: diagnosis and management issuesSamuel Lévy (Marseille, FR)

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SUNDAY JUNE 16, 2019

SUNDAY JUNE 16, 20192:00 PM - 3:30 PMROOM JOLIETTESession SP-02

Aggressive ablation for ventricular tachycardia?Chairpersons: Richard Schilling (London, GB), Douglas Packer (Rochester, USA)

1. Best ablative guides for ARVC, sarcoid, myocarditis, and other offbeat ventricular tachycardiasDavid Wilber (Chicago, USA)

2. Role of intracardiac ultrasound in guided VT ablation: from PVCs to ICE-guided structuralinterventionsT. Jared Buench (Salt Lake City, USA)

3. Recent Clinical outcomes of advanced VT ablation: “Photon vs. particle therapy”?Phillip S. Cuculich (Saint Louis, USA)

4. Potential effect of VT ablation on mortalityKarl-Heinz Kuck (Hamburg, DE)

SUNDAY JUNE 16, 20192:00 PM - 3:30 PM ROOM SAINT JEANSession SP-03

Cardiovascular complications of energy drinksChairpersons: Samuel Levy (Marseille, FR), Carla Riganti (Naples, IT)

1. Composition of commercially available energy drinksLuca Santini (Rome, IT)

2. Reports of cardiovascular complications of energy drinksAli Oto (Ankara, TR)

3. Role of caffeine and other ingredients contained in energy drinksAlessandro Capucci (Ancona, IT)

4. ECAS recommendation statement Maurizio Santomauro and Carla Riganti (Naples, IT)

SUNDAY JUNE 16, 20192:00 PM - 3:30 PMROOM MUCEMSession SP-04

Septal accessory pathways: diagnosis, localization and catheter ablation(Interactive case discussions)

Session proposed and conducted by Jasbir Sra (Milwaukee, USA), Warren Jackman (Milwaukee and Oklahoma City, USA) and Stavros Stavrakis (Oklahoma City, USA)

1. Anteroseptal pathway-interactive case discussion

2. Left vs right mid septal pathway-interactive case discussion

3. Postero-septal vs accessory pathway from the middle cardiac vein: interactive case discussion

4. Discussion with audience participation

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SUNDAY JUNE 16, 2019

SUNDAY JUNE 16, 20192:00 PM - 3:30 PMROOM NOTRE DAMESession SP-05

Management of lead extraction patientsChairpersons: Charles Kennergren (Gothenburg, SE), Eli Ovsyshcher (Beersheba, IL)

1. Preoperative imaging for transvenous lead extractionDonald Hegland (Durham, USA)

2. Intraoperative imaging for transvenous lead extractionHemal Nayak (Chicago, USA)

3. Prepping and protection during vascular emergenciesBruce Wilkoff (Cleveland, USA)

4. Surgical rescue for SVC and other vascular emergenciesJamil Bashir (Vancouver, CA)

SUNDAY JUNE 16, 20192:00 PM - 3:30 PMROOM LACYDON Chaired Poster session B

Posters displayed from 2:00 pm to 5:00 pmPresenters and Chairpersons presents from 2:00 pm to 3:30 am

ATRIAL FIBRILLATION ABLATIONChairpersons: Roger Winkle (Palo Alto, USA), Brian Olshansky (Iowa City, USA)

14.09 Abstract 18-18Electrogram amplitude is lower at persistent atrial fibrillation termination sites compared to non-terminating control sitesJunaid Zaman1, Nosheen Moosvi2, Rogers Albert2, Alhusseini Mahmood2, Tina Baykaner2, Gabriela Meckler2, FatemahShenasa2, Mark Swerdlow2, Christopher Kowalewski2, Paul Zei3, Shirley Park2, Chad Brodt2, Mohan Viswanathan2,Paul Wang2, Wouter Rappel4, Sanjiv Narayan2

1Imperial College, London, United Kingdom, 2Stanford University, Palo Alto, United States, 3Harvard University, Boston,United States, 4University of California, San Diego, United States

14.10 Abstract 14-11Gender differences among the younger atrial fibrillation patients undergoing catheter ablation: ananalysis of the nationwide inpatient sample 2005-2014. Dinesh Voruganti1, Naga Venkata Krishna Pothineni2, Ghanshyam Shantha3, Sushma Dugyala4, Babu P Mohan4,Abhishek Deshmukh5, Michael Giudici11University of Iowa, Iowa City, United States, 2University of Arkansas Medical Center, Little Rock, United States,3University of Michigan, Ann Arbor, United States, 4University of Alabama, Tuscaloosa, United States, 5Mayo Clinic,Rochester, United States

14.11 Abstract 28-14Ablation progressively coalesces organized atrial areas prior to termination of persistent atrialfibrillationAlbert Rogers1, Neal Bhatia1, Samir Hossainy1, Nosheen Moosvi1, Abhinav Singh1, Mahmood Alhusseini1, Chad Brodt1,Tina Baykaner1, Paul Wang1, Wouter-Jan Rappel2, Sanjiv Narayan1

1Stanford University, Stanford, United States, 2 UC San Diego, La Jolla, United States

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14.12 Abstract 28-10Termination of persistent atrial fibrillation is more frequent using spatiotemporal dispersion mappingcompared to complex fractionated electrogram guided ablationJunaid Zaman1, Sharad Agarwal11Royal Papworth Hospital, Cambridge, United Kingdom

14.13 Abstract 28-12Deep convolutional neural networks (CNN) to analyze and interpret intracardiac mapping in atrialfibrillationMahmood Alhusseini1, Firas Abuzaid1, Paul Clopton1, Albert Rogers1, Tina Baykaner1, Miguel Rodrigo1, Wouter-JanRappel2, Peter Bailis1, Matei Zaharia1, Sanjiv M Narayan1

1Stanford University, Stanford, United States, 2Univiersity of California, San Diego, La Jolla, United States

14.14 Abstract 18-26Cryoballoon pulmonary venous isolation causes mild but significant elevation of serum creatinineNicholay Teodorovich1, Nir Zehavi1, Yonatan Kogan1, Jacob George1, Moshe Swissa1

1Kaplan Medical Center, Rehovot, Israel

14.16 Abstract 15-16Novel 3D multimodal atlases enable visualization of cases of termination of persistent atrial fibrillationNosheen Moosvi1, Albert Rogers1, Mahmood Alhusseini1, Neal Bhatia1, Tina Baykaner1, Mintu Turakhia1, SanjivNarayan1

1Stanford University, Stanford, United States

Antiarrythmic Therapy14.17 Abstract 08-10QT interval prolongation under amiodarone: impact and predictors in the amiotox registry Marouane Mahjoub1, Mejdi Ben Messaoud1, Fedoua Omri1, Mehdi Boussada1, Nidhal Bouchahda1, Majed Hassine1,Zohra Dridi1, Fethi Betbout1, Habib Gamra1

1Cardiology department A: Fattouma Bourguiba University Hospital, Monastir, Monastir, Tunisia

Supraventricular Tachycardia

14.18 Abstract 12-11Interest of parahissian stimulation in differential diagnosis of supra ventricular tachycardiaMarouane Mahjoub1, sana ouali2, Manel Ben halima2, Mejdi Ben Messaoud1, Mehdi Boussada1, Nidhal Bouchahda1,Majed Hassine1, Zohra Dridi1, Fethi Betbout1, Habib Gamra1, Sami Mourali21Cardiology department A: Fattouma Bourguiba University Hospital, Monastir, Monastir, Tunisie, 2Cardiologydepartment University Hospital La Rabta Tunis, Tunis, Tunisie

3:30 PM - 4:00 PMCoffee break and visit to posters

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SUNDAY JUNE 16, 2019

SUNDAY JUNE 16, 20194:00 PM - 5:30 PMROOM GRAND LARGESession SP-06

Supported by an educational grant from Bayer AG

Anticoagulation using DOACs in atrial fibrillation: what is new?Chairpersons: Thomas Deering (Atlanta, USA), Christine Albert (Boston, USA)

1. CardioversionEugene Crystal (Toronto, CA)

2. AF AblationHugh Calkins (Baltimore, USA)

3. Direct oral anticoagulants in patients with renal impairment Ali Oto (Ankara, TR)

4. Advances and limitations in the real wordThomas Deering (Atlanta, USA)

5. AF DOAC ControversiesAndrea Russo (Camden, USA)

SUNDAY JUNE 16, 20194:00 PM - 5:30 PMROOM ESTAQUESession AF-02

Trials and meta-analyses in atrial fibrillation and their impact on current practiceChairpersons: Riccardo Cappato (Milan, IT), Antony Chu (Providence, USA)

1. Interpretation of the CABANA Trial resultsDouglas L Packer (Rochester, USA)

2. Interpretation of the CASTLE Trial results Johannes Brachmann (Coburg, DE)

3. Targeting ganglion plexi in AF ablation with and without PV isolationSunny Po (Oklahoma City, USA)

4. Targeting complex electrograms with and without PV isolation Julien Seitz (Marseille, FR)

SUNDAY JUNE 16, 20194:00 PM - 5:30 PMROOM JOLIETTESession SD-01

How to optimize pulmonary vein isolation?Chairpersons: Ellen Hoffmann (Munich, DE), David Haines (Royal Oak, USA)

1. 20 years of pulmonary vein isolation – Contemporary outcomesKenzo Hirao (Tokyo, JP)

2. Strategies to optimize PVI using radiofrequency energyDavid Haines (Royal Oak, USA)

3. Strategies to optimize PVI using cryoablationFlorian Straube (Munich, DE)

4. Role of contact forceCarlo Lavalle (Rome, IT)

5. Additional sites beyond the pulmonary veinsLi-Wei Lo (Taipei, TW)

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SUNDAY JUNE 16, 2019

SUNDAY JUNE 16, 20194:00 PM - 5:30 PM ROOM SAINT JEANSession SP-07

ECG interpretation course (Part 1: conduction disturbances)A tribute to Agustin Castellanos Jr (1927-2017)Chairpersons: Sanjeev Saksena (Warren, USA), Mark Estes III (Boston, USA)

1. The Bayes syndrome Antoni Bayes de Luna (Barcelona, ES)

2. What is new in congenital AV block management? George van Hare (St Louis, USA)

3. Conduction abnormalities complicating acute myocardial infarctionSamuel Levy (Marseille, FR)

4. ECG of bradyarrhythmiasBengt Herweg (Tampa, USA)

SUNDAY JUNE 16, 20194:00 PM - 5:30 PMROOM MUCEMSession SP-08

Challenges in clinical care of patients with the dysautonomic syndromesChairpersons: David Benditt (Minneapolis, USA), David Cannom (Los Angeles, USA)

1. Clinical characteristics that assure the diagnosis of POTS and misleading symptoms Brian Olshansky (Iowa, USA)

2. Role of autoimmune disorders and mast cell diseases in dysautonomic syndromesDavid Benditt (Minneapolis, USA)

3. Role of clinical laboratory testing for the differential diagnosis of dysautonomic syndromesGert van Dijk, (Leiden, NL)

4. Impact of education and support in the care of patients with dysautonomic syndromes?Richard Sutton (Monaco, MC)

SUNDAY JUNE 16, 20194:00 PM - 5:30 PMROOM NOTRE DAMESession SP-09

Complications during electrophysiological proceduresChairpersons: Dipen Shah (Geneva, CH), Prapa Kanagaratnam (London, GB)

1. Complications of catheter ablation of atrial fibrillation and flutter in GermanyGerhard Steinbeck (Munich, DE)

2. Arrhythmic emergencyStephanie Fichtner (Munich, DE)

3. Pericardial tamponadeNoel Boyle (Los Angeles, USA)

4. Thermic esophagus damageThomas Deneke (Bad Neustadt, DE)

5. My worst nightmareRichard Schilling (London, GB)

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SUNDAY JUNE 16, 2019

Room LA MAJOR5:30 PM to 6:00 PM

Philippe Coumel Special lecture

Catheter ablation of ventricular tachycardiain patients with ischemic heart disease By

Opening ceremony 6:00 PM to 7:00 PMEulogy to Giants

Outstanding Achievement Awards

Outstanding Support Awards

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Prof. Karl-Heinz Kuck(Hamburg, DE)

Masood Akhtar, MD

Brian Olshansky, MD Luca Santini, MD

David Wilber, MD Alessandro Capucci, MD

Gerard Guiraudon, MD Paul Puech, MD

Karl-Heinz Kuck, MD

Page 23: This program is endorsed by Aix-Marseille UniversityThis program is endorsed by Aix-Marseille University ... Abstract Presentation The abstracts accepted for oral or poster presentation

MONDAY JUNE 17, 2019

MONDAY JUNE 17, 20198:30 AM - 10:00 AMROOM GRAND LARGESession SD-02

Prevention of sudden cardiac death (SCD) in young adultsChairpersons: Mark N. Estes III (Pittsburgh, USA), Xavier Jouven (Paris, FR)

1. Physiopathology of SCDMunther K. Homoud (Boston, USA)

2. Risk stratification of SCD in young adults: Have we progressed?Domenico Corrado (Padua, IT)

3. Sudden cardiac death during sports activitiesEloi Marijon (Paris, FR)

4. Autopsy as a tool in the prevention of sudden death in the youngAudrey Farrugia-Jacamon (Strasbourg, FR)

MONDAY JUNE 17, 20198:30 AM - 10:00 AMROOM ESTAQUESession AF-03

Ablation for atrial fibrillation (AF): clinical challenges and new frontiersChairpersons: Neil Sulke (Eastbourne, GB), Antony Chu (Providence, USA)

1. Challenges in persistent AF ablation: Targets beyond the PVs Walid Saliba (Cleveland, USA)

2. Treatment strategies post CABANA: Did we miss the real questions in AF care? Ayman Hussein (Cleveland, USA)

3. Simultaneous LAA occlusion and atrial fibrillation ablation: is it a risk or a benefit? Lucas Boersma (Amsterdam, NL)

4. Anticoagulation cessation after successful ablation: Should we do it? Antony Chu (Providence, USA)

MONDAY JUNE 17, 20198:30 AM - 10:00 AM ROOM JOLIETTESession SP-10

New guidelines in arrhythmia management: How should these change patient care?Chairpersons: John Camm (London, GB), Robert Hauser (Minneapolis, USA)

1. Ventricular arrhythmia and sudden death prevention: Are we saving lives? Christine Albert (Boston, USA)

2. Catheter and surgical ablation for AF: Where are we in 2018? Hugh Calkins, Baltimore, USA)

3. Bradycardia and device management: How do the new guidelines Impact patient care? Massimo Santini (Rome, IT)

4. Can patients with a non-MRI conditional device undergo a safe MRI? Julia Indik (Tucson, USA)

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MONDAY JUNE 17, 2019

MONDAY JUNE 17, 20198:30 AM - 10:00 AMROOM SAINT JEANSession WS-07

Risk of sudden cardiac death in the Brugada syndromeChairpersons: Dobromir Dobrev (Essen, DE), Bo G. Winkel (Copenhagen DK)

1. Pathogenesis of the Brugada syndrome Bo G. Winkel (Copenhagen DK)

2. Pharmacotherapy of Brugada syndromeLena Rivard (Montreal, CA)

3. Indications of implantable cardioverter defibrillator in the Brugada SyndromeDaniel Steven (Cologne, DE)

4. Debate: Catheter ablation plays a role in the Brugada syndrome (30min)Protagonist: Philippe Chevalier (Lyon, FR)

Antagonist: Riccardo Cappato (Milan, IT)

MONDAY JUNE 17, 20198:30 AM - 10:00 AMROOM MUCEMSession SP-11

Stroke prevention in atrial fibrillation – State of the artChairpersons: Andrea Russo (Camden, USA), Ernst Vester (Dusseldorf, DE)

1. Pharmacological stroke preventionHeidi Estner (Munich, DE)

2. Endocardial LAA OcclusionThorsten Lewalter (Munich, DE)

3. Epicardial LAA exclusionLuigi Di Biase (New-York, USA)

4. Surgical LAA ClosureSacha Salzberg, (Zurich, CH)

MONDAY JUNE 17, 20198:30 AM - 10:00 AMROOM LACYDON Chaired Poster session C

Posters displayed from 8:30 AM to 12:00 PM

Presenters and Chairpersons presents from 9:00 am to 10:30 am

Sudden death and ICD & new concepts in cardiac pacing: temporary pacingChairpersons: Richard Sutton (Monaco, MC), Promund Obel (Johannesburg, ZA)

14.19 Abstract 08-12Reversible change of atrioventricular conduction disturbances in permanent pacemaker patients aftertranscatheter aortic valve implantationHidemori Hayashi1, Gaku Sekita1, Haruna Tabuchi1, Takashi Tokano1, Masataka Sumiyoshi1, Yuji Nakazato1, HiroyukiDaida1. 1Department of Cardiovascular Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan

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MONDAY JUNE 17, 2019

14.20 Abstract 23-16The economics of temporary permanent pacemakersChad Ward1, Ala Mohsen2, Oluwaseun Adeola1, Shubha Deep Roy1, Musab Alqasrawi1, Tyler Rasmussen1, DineshVoruganti1, Michael Giudici11University of Iowa, Iowa City, IA, United States, 2Louisiana State University Health Science Center, River Ridge, LA,United States

14.21 Abstract 23-14Test drives, TAVRs, bedsavers and Intensive Care Unit lifesavers: the many uses of the temporary-permanent pacemaker – a single center experienceOluwaseun Adeola1, Chad Ward1, Shuba Deep Roy1, Amgad Mentias1, Michael Giudici11University of Iowa, Iowa City, United States

14.22 Abstract 23-11Pacemaker “test-drives” – try before you buy case studiesMichael Giudici1, Steven Bailin1, Thein Aung1, Cyrus Kocherla1

1University of Iowa Hospitals, Iowa City, United States

14.23 Abstract 23-10Utilities and outcomes associated with the use of temporary-permanent pacemakers: a single centerexperienceAla Mohsen1, Musab Alqasrawi1, Shubha Deep Roy1, Ghanshyam Shantha1, Mohsan Chaudhry1, Manju Jayanna1,Dinesh Voruganti1, Tyler Rasmussen1, Chad Ward1, Michael Giudici11University of Iowa, Iowa City, United States

Sudden death and implantable defibrillators

14.24 Abstract 24-11Midterm super-response to LV only fusion pacing CRT without RV lead: clinical and echocardiographicpredictorsCristina Vacarescu1, Emilia Goanta2, Lucian Petrescu1, Constantin-Tudor Luca3, Cristian Mornos3, Simina Crisan3,Ramona Cozlac3, Dragos Cozma3

1”Victor Babes” University of Medicine and Pharmacy, Timisoara, Romania, 2Emergency Clinical County Hospital,Craiova, Romania, 3 Institute of Cardiovascular Diseases, Timisoara, Romania

14.25 Abstract 25-10Incidence of defibrillator lead failure following implant of newer-generation left ventricular assistdevicesMiguel Leal1, Anne Barnett1, Kosuke Ujihira1, Takushi Kohmoto1

1University of Wisconsin, Madison, United States

Supraventicular Tachycardia

14.26 Abstract 12-12Interest of the transition zone to determine the mecanism of supraventricular tachycardia Marouane Mahjoub1, Sana Ouali2, Manel Ben Halima2, Mejdi Ben Messaoud1, Nidhal Bouchahda1, Mehdi Boussada1,Majed Hassine1, Zohra Dridi1, Fethi Betbout1, Habib Gamra1, Sami Mourali21Cardiology department A: Fattouma Bourguiba University Hospital, Monastir, Monastir, Tunisie, 2 2- Cardiologydepartment University Hospital La Rabta Tunis, Tunis, Tunisie

10:00 AM - 10:30 AMCoffee break and visit to posters

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MONDAY JUNE 17, 2019

MONDAY JUNE 17, 201910:30 AM - 12:00 PMROOM GRAND LARGEAbstract Oral Session 5

Genetics in cardiac arrhythmiasChairpersons: Peter van Tintelen (Utrecht, NL), Stefan Kääb (Munich, DE)

05.1 Abstract 03-10Whole genome sequencing identified a homozygous missense variant in PNPLA2 as a cause ofarrhythmogenic cardiomyopathyGuangran Guo1, Man Rao1, Jiangping Song1

1Fuwai hospital, Beijing, China

05.2 Abstract 03-11Next generation sequencing for Latvian arrhythmogenic right ventricular cardiomyopathy registry patientsLuize Bidina1, Dmitrijs Rots1, Kaspars Kupics2, Laima Caunite2, Linda Gailite1, Oskars Kalejs2

1Riga Stradins University, Riga, Latvia, 2Pauls Stradins Clinical university hospital, Riga, Latvia

05.3 Abstract 03-12Nonunique mutations in families with arrhythmogenic right ventricular cardiomyopathy originate fromancient foundersFreyja van Lint1, Brittney Murray2, Crystal Tichnell2, Rob Zwart1, Nuria Amat2, Ronald Lekanne Deprez1, SvenDittmann3, Birgit Stallmeyer3, Hugh Calkins2, Jasper van der Smagt4, Arthur van den Wijngaard5, Dennis Dooijes4,Paul van der Zwaag6, Eric Schulze-Bahr3, Daniel Judge7, Jan Jongbloed6, J. Peter van Tintelen4, Cynthia James2

1Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, Netherlands, 2Johns HopkinsUniversity, Baltimore, Maryland, United States, 3University Hospital Münster, Münster, Germany, 4University MedicalCenter Utrecht, Utrecht, Netherlands, 5Maastricht University Medical Centre, Maastricht, Netherlands, 6University ofGroningen, University Medical Center Groningen, Groningen, Netherlands, 7Medical University of South Carolina,Charleston, South Carolina, United States

05.4 Abstract 03-14Influence of exercise on arrhythmic phenotype in carriers of the founder mutation p.Arg14del in PLNFreyja van Lint1, Thomas Verstraelen1, Weijja Wang2, Laurens Bosman3, Paul van der Zwaag4, Folkert Asselbergs3,Maarten van den Berg4, Arthur Wilde1, Cynthia James2, J. Peter van Tintelen3

1Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, Netherlands, 2Johns HopkinsUniversity, Baltimore, Maryland, United States, 3University Medical Center Utrecht, Utrecht, Netherlands, 4Universityof Groningen, University Medical Center Groningen, Groningen, Netherlands

05.5 Abstract 03-16Variation of phenotype in carriers of a (P. LEU729DEl) SCN5A founder mutationRob Roudijk1, Peter Loh2, Jeroen van der Heijden2, Marcoen Scholten3, Arthur Wilde4, Folkert Asselbergs2, RichardHauer2, Anneline te Riele2, Peter van Tintelen4

1Netherlands Heart Institute, Utrecht, Netherlands, 2UMC Utrecht, Utrecht, Netherlands, 3Medisch SpectrumTwente, Enschede, Netherlands, 4Amsterdam UMC, Amsterdam, Netherlands

05.6 Abstract 03-15The first family with progressive cardiac conduct defect due to a nonsense mutation (C.1443C>A) inLMNA genePeng Fan1, Di Zhang2, Kun-Qi Yang1, Ya-Xin Liu2, Lin-Ping Wang1, Xian-Liang Zhou1

1Department of Cardiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy ofMedical Sciences and Peking Union Medical College, Beijing, China, 2Emergency and Critical Care Center, FuwaiHospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking UnionMedical College, Beijing, China

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MONDAY JUNE 17, 2019

MONDAY JUNE 17, 2019110:30 AM - 12:00 PMROOM ESTAQUEAbstract Oral Session 6

Atrial fibrillation ablationChairpersons: Michael Giudici (Iowa City, USA), Sam Hanon (New York, USA)

06.1 Abstract 18-24The next generation visually guided laser balloon ablation system for pulmonary vein isolation: firstclinical experience – the MERLIN registryChristian-Hendrik Heeger1, Huong Lan Phan1, Roza Meyer-Saraei1, Thomas Fink1, Spyridon Liosis1, BenBrueggemann1, Niels Große1, Julia Vogler1, Bezhad Fahimi1, Dong An1, Makoto Sano1, Ingo Eitel1, Harald Langer1,Charlotte Eitel1, Roland Tilz1

1University Heart Center Lübeck, Lübeck, Germany

06.2 Abstract 18-22Phrenic nerve injury during pulmonary vein isolation using the second-generation cryoballoon:characteristics and follow-up – first results of the worldwide YETI registryRoland Tilz1, Alexander Pott2, Andreas Rillig3, Andreas Metzner4, Serkan Cay5, Niels Große1, Shinsuke Miyazaki6,Arash Aryana7, Joachim R. Ehrlich8, Hagen Wirth2, Verena Tscholl9, Huang Yinhao10, Evgeny Lyan11, Martin Martinek12,Osamu Inaba13, Julian K.R. Chun14, Karl-Heinz Kuck3, Tilman Dahme2, Christian-H. Heeger1

1University of Luebeck, Luebeck, Germany, 2University of Ulm, Ulm, Germany, 3Asklepios St. Georg, Hamburg,Germany, 4Asklepios Harburg, Hamburg, Germany, 5Yuksek Ihtisas Heart-Education and Research Hospital , Ankara,Turkey, 6Tsuchiura Kyodo Hospital, Tsuchiura, Ibaraki, Japan, 7Mercy General Hospital and Dignity Health Heart andVascular Institute, , Sacramento, California, United States, 8St. Josefs-Hospital , Wiesbaden, Germany, 9CharitéCampus Benjamin Franklin, Berlin, Germany, 10Nanjing Drumtower Hospital, Nanjing, China, 11Herzzentrum BadBevensen, Bad Bevensen, Germany, 12Ordensklinikum , Linz, Austria, 13Red Cross Hospital, Saitama, Japan, 14CCB/ Med. Klinik III, Kardiologie, Markuskrankenhaus , Frankfurt am Main, Germany

06.3 Abstract 18-14Ablation index for pulmonary vein isolation: inter-operator reproductibilityAntoine Lepillier1, F Solimene2, E De Ruvo3, M Scaglione4, M Anselmino5, Frederic Sebag6, D Pecora7, M Gallagher8,M Rillo9, G Viola10, L Rossi11, V De Santis12, M Landolina13, E Bertaglia14, Giuseppe Stabile15

1Centre Cardiologique Du Nord, Saint-Denis, France, 2Clinica Montevergine, Mercogliano , Italy, 3Policlinico Casilino,Roma, Italy, 4Ospedale Cardinal Massaia, Asti, Italy, 5A.O.U. Citta della Salute e della Scienza di Torino, Torino, Italy,6Institut Mutualiste Montsouris, PARIS, France, 7Fondazione Poliambulanza, Brescia, Italy, 8St George’s Hospital,London, United Kingdom, 9Casa di Cura Villa Verde, Taranto, Italy, 10Ospedale San Francesco, Nuoro, Italy,11Ospedale Civili Guglielmo da Saliceto, Piacenza, Italy, 12Istituto Clinico Sant’Ambrogio, Milano, Italy, 13OspedaleMaggiore di Crema, Crema, Italy, 14Department of Cardiac, Thoracic, and Vascular Sciences, University of Padova,Padova, Italy, 15Clinica Mediterranea, Napoli, Italy

06.4 Abstract 18-13Homogenization of low voltage aereas for the ablation of persistent atrial fibrillationAntoine Lepillier 1, Olivier Paziaud 1, Olivier Piot 1, Gilles Lascault 1, Xavier Copie 11 Centre Cardiologique Du Nord, Saint-Denis, France

06.5 Abstract 04-10Targeting autonomic upstream drivers of atrial fibrillation to treat paroxysmal atrial fibrillation withoutpulmonary vein isolationMin-young Kim1, Belinda Sandler1, Markus Sikkel1, Chris Cantwell1, Kevin Leong1, Vishal Luther2, Louisa Malcolme-Lawes2, Afzal Sohaib2, Michael Koa-Wing 2, Fu Siong Ng 1, Norman Qureshi2, Zachary Whinnett2, Ross Hunter3, DavidTomlinson4, Nicholas Peters1, Phang Boon Lim2, Nicholas Linton1, Prapa Kanagaratnam2

1Imperial College London, London, United Kingdom, 2Imperial College NHS Trust, London, United Kingdom, 3St Bartholomew’s Hospital, London, United Kingdom, 4Derriford Hospital, Plymouth, United Kingdom

06.6 Abstract 04-11 27

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The ganglionated plexuses and their electrophysiological phenomena: evidence for their role inpathogenesis of atrial fibrillationMin-young Kim1, Belinda Sandler1, Markus Sikkel1, Kevin Leong2, Vishal Luther2, Louisa Malcolme-Lawes2, AfzalSohaib3, Michael Koa-Wing2, Fu Siong Ng2, Norman Qureshi2, Zachay Whinnett2, David Tomlinson4, Ross Hunter3,Nicholas Peters1, Phang Boon Lim2, Nicholas Linton1, Prapa Kanagaratnam2

1Imperial College London, London, United Kingdom, 2Imperial College NHS Trust, London, United Kingdom, 3StBartholomew’s Hospital, London, United Kingdom, 4Derriford Hospital, Plymouth, United Kingdom

MONDAY JUNE 17, 201910:30 AM - 12:00 PMROOM SAINT JEANAbstract Oral Session 7

Anticoagulation and stroke preventionChairpersons: Thomas Deering (Atlanta, USA), Riccardo Cappato (Milan, IT)

07.1 Abstract 15-18Pacemaker and implanted cardioverter defibrillator without reversal of DOAC therapyMaurizio Santomauro1, Raffaele Giordano1, Francesco Elia1, Mario Alberto Santomauro1, Gabriele Iannelli1, CarlaRiganti1, Mario Petretta1, Domenico Bonaduce1

1Department of Cardiovascular Emergency, Internal medicine, Geriatric, Azienda Universitaria Federico II Napoli,Napoli (NA), Italy

07.2 Abstract 23-18Lead extraction without interruption of anticoagulation: a retrospective outcomes comparisonMiguel Leal1, Graham Adsit1, Jill Triphan1, Anne Barnett1, Amanda Breuer1, Micah Roberts1

1University of Wisconsin, Madison, United States

07.3 Abstract 15-32Prescription of oral anticoagulation (OAC) and reasons reported for non-use of OAC in patients withatrial fibrillation: data from the German atrial fibrillation network (AFNET) 2 registryAndrea Gerth1, Michael Nabauer1, Paulus Kirchhof2, Gerhard Steinbeck3, Günter Breithardt41Ludwig-Maximilians University, Medical Hospital I, Munich, Germany, 2University of Birmingham, Institute ofCardiovascular Sciences, Birmingham, United Kingdom, 3Klinikum Starnberg, Starnberg, Germany, 4UniversityHospital Münster, Department of Cardiovascular Medicine, Münster, Germany

07.4 Abstract 15-13Watchman complications reported in the manufacturer and user facility device experience databaseShady Henien1, Lauren Rousseau2, Antony Chu2

1Brown University - Department of Cardiology, Providence, United States, 2Brown University, Providence, UnitedStates

07.5 Abstract 32-10Efficacy of adding or replacing low dose novel oral anticoagulants to conventional antiplatelet/anticoagulation therapy for the prevention of non-cardiovascular death in patients with coronary arterydisease: a systematic review and meta-analysisMichela Giustozzi, MD1,2, Mauro Chiarito, MD1, Martina Briani, MD1, Letizia Riva, MD, PhD3, Gianluca Bonitta, MSc1,Hussam Ali, MD1, Pier Paolo Lupo, MD1, Cristina Balla, MD4, Francesco Furlanello, MD1, Corrado Lodigiani1, GiulioStefanini, MD1, Riccardo Cappato, MD1,Arrhythmia and EP Research Center, IRCCS Humanitas Research & University Hospital, Rozzano (Milan), Italy

07.6 Abstract 14-14

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Trends outcomes of hospitalizations for atrial fibrillation-flutter in heart transplant recipients: an insightfrom the Nationwide Inpatient Sample: 2005-2014Dinesh Voruganti1, Ghanshyam Shantha2, Sushma Dugyala3, Naga Venkata Krishna Pothineni4, Abhishek Deshmukh5,Shubha Deep Roy1, Babu P Mohan3, Alexandros Briasoulis1, Michael Giudici11University of Iowa Hospitals and Clinics, Iowa City, United States, 2University of Michigan, Ann Arbor, United States,3University of Alabama, Tuscaloosa, United States, 4University of Arkansas Medical Center, Little Rock, United States,5 Mayo Clinic, Rochester, United States

MONDAY JUNE 17, 201910:30 AM - 12:00 PMROOM MUCEMAbstract Oral Session 8

Hereditary lethal syndromesChairpersons: Richard Hauer (Utrecht, NL), Philippe Chevalier (Lyon, FR)

08.1 Abstract 19-15ECG T-wave predictors of positive ajmaline testing and markers of arrhythmic risk in patients with apositive ajmaline test Neil Srinivasan1, Kieran Patel1, William Young1, Gurpeet Dhillon1, Rui Providencia1, Max Finzel1, Michele Orini1, MartinLowe1, Richard Schilling1, Pier Lambiase1

1Barts Heart Centre, London, United Kingdom

08.2 Abstract 19-21Prediction of ventricular arrhythmias in patients with a spontaneous Brugada type 1 pattern: the keyis in the ECGAntoine Delinière1, Adrian Baranchuk2, Joris Giai3, Francis Bessière1, Delphine Maucort-Boulch3, Pascal Defaye4, EloiMarijon5, Olivier Le Vavasseur6, Dan Dobreanu7, Scridon Alina7, Antoine Da Costa8, Etienne Delacrétaz9, ClaudeKouakam10, Romain Eschalier11, Fabrice Extramiana12, Antoine Leenhardt12, Haran Burri13, Pierre-François Winum14,Jérôme Taieb15, Jérôme Bouet15, Mathieu Fauvernier3, Horia Rosianu16, Adrien Carabelli4, Benjamin Duband11, PhilippeChevalier1

1Department of Rhythmology, Reference Center for Inherited Cardiac Arrhythmias, Louis Pradel CardiovascularHospital, Hospices Civils de Lyon, Institut Neuromyogène, Université Lyon 1, Lyon, France, 2Department of Medicine,Queen’s University, Kingston, Canada, 3Department of Biostastics and Bioinformatics, Hospices Civils de Lyon, UMRCNRS 5558 Laboratoire de Biométrie et Biologie Evolutive, Equipe Biostatistique Santé, Université Lyon 1, Lyon,France, 4Rhythmology Unit, Department of Cardiovascular Medicine, University Hospital of Grenoble, Grenoble ,France, 5Department of Cardiology, Georges Pompidou European Hospital, Paris, France, 6Department ofCardiovascular Medicine, North-West Hospital, Villefranche-sur-Saône, France, 7Physiology Department, Universityof Medicine and Pharmacy of Târgu Mureș, Târgu Mureș, Romania, 8Department of Cardiology, University Hospitalof Saint-Etienne, Saint-Etienne, France, 9Cecil Cardiovascular Center, Lausanne, Switzerland, 10Rhythmology Unit,Cardiovascular Hospital, University Hospital of Lille, Lille, France, 11Department of Cardiology, Gabriel MontpiedHospital, University Hospital of Clermont-Ferrand, Clermont-Ferrand, France, 12Rhythmology Unit, CNMR, MaladiesCardiaques Héréditaires Rares, Department of Cardiology, Bichat Hospital, Paris, France, 13Department of Cardiology,University Hospital of Geneva, Geneva, Switzerland, 14Department of Cardiovascular Medicine, University Hospitalof Nîmes, Nîmes, France, 15Department of Cardiology, Aix-en-Provence Hospital, Aix-en-Provence, France,16Department of Cardiology, Niculae Stancioiu Heart Institute, Cluj-Napoca, Romania

08.3 Abstract 19-10Brugada syndrome risk stratification - evaluation of clinical and ECG risk markers in a multicenterinternational primary prevention cohortShohreh Honarbakhsh1, Rui Providencia1, Jorge Garcia-Hernandez2, Claire Martin3, Ross J Hunter1, Wei Y Lim1,Claire Kirkby1, Ardalan Sharifzadehgan4, Victor Waldmann4, Eloi Marijon4, Carmen Munoz-Esparza5, Javier Lacunza6,Juan Gimeno-Blanes5, Benedicte Ankou7, Philipe Chevalier8, Natalia Antonio9, Luis Elvas9, Silvia Castelletti10, LiaCrotti 10, Peter Schwartz10, Maurício Scanavacca11, Francisco Darrieux11, Luciana Sacilotto11, Johanna Mueller-Leisse12,Christian Veltmann12, Nuno Cortez-Dias13, Pedro António Silverio13, João de Sousa13, Pedro Adragão14, Diogo

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Cavaco14, Francisco Costa14, Ziad Khoueiry15, Serge Boveda16, Maria-João Sousa16, Zeynab Jebberi16, Patrick Heck17,Sarju Mehta3, Giulio Conte18, Tardu Oezkarta18, Angelo Auricchio18, Martin Lowe1, Richard J Schilling1, David Prieto-Merino19, Pier D Lambiase1

1Barts Heart Centre, Barts Health NHS trust, London, United Kingdom, 2Farr Research Institute, London, UnitedKingdom, 3Royal Papworth Hospital NHS Foundation Trust, Cambridge, United Kingdom, 4Cardiology Department,European Georges Pompidou Hospital, Paris, France, 5Inherited Cardiac Disease Unit, University Hospital VirgenArrixaca, Murcia, Spain, 6ŢInherited Cardiac Disease Unit, University Hospital Virgen Arrixaca, Murcia, Spain,7Rhythmology department, Hôpital Cardiovasculaire Louis Pradel, Lyon, France, 8ŦRhythmology department, HôpitalCardiovasculaire Louis Pradel, Lyon, France, 9Cardiology department, Coimbra Hospital and University Centre,Coimbra, Portugal, 10Laboratory of Cardiovascular Genetics, Center for Cardiac Arrhythmias of Genetic Origin, IRCCSIstituto Auxologico, Milan, Italy, 11Arritmia, Instituto do Coracao, Hospital das Clinicas HCFMUSP, Faculdade deMedicina, Universidade de Sao Paulo, Sao Paulo, Brazil, 12Department of Cardiology and Angiology. HannoverMedical School, Hannover, Germany, 13Department of Cardiology, Santa Maria University Hospital, Lisbon AcademicMedical Centre and Cardiovascular Centre of the University of Lisbon, Faculty of Medicine, Lisbon, Portugal,14Cardiology department, Santa Cruz Lisboa hospital, Lisbon, Portugal, 15Institute Saint Pierre, Perpignan, France,16Clinique Pasteur, Toulouse, France, 17Addenbroke’s Hospital, Cambridge, United Kingdom, 18CardiacElectrophysiology Unit, Division of Cardiology, Fondazione Cardiocentro Ticino, Lugano, Switzerland, 19Faculty ofEpidemiology and population health, London School of Hygiene and Tropical Medicine, London, United Kingdom

08.4 Abstract 07-17Clinical validation of the 2010 task force criteria for arrhythmogenic right ventricular cardiomyopathy:simplification improves diagnostic accuracyLaurens Bosman1, Julia Cadrin-Tourigny2, Mimount Bourfiss1, Mounes Aliyari Ghasebeh3, Apurva Sharma3, CrystalTichnell3, Rob Roudijk1, Brittney Murray3, Harikrishna Tandri3, Ihab Kamel3, Stefan Zimmerman3, Johannes Reitsma1,Folkert Asselbergs1, J. Peter van Tintelen1, Jeroen van der Heijden1, Richard Hauer4, Hugh Calkins3, Cynthia James3,Anneline te Riele4

1UMC Utrecht, Utrecht, Netherlands, 2Montreal Heart Institute, Montreal, Canada, 3Johns Hopkins Hospital, Baltimore,United States, 4Netherlands Heart Institute, Utrecht, Netherlands

08.5 Abstract 07-16Diagnostic value of native T1 mapping in arrhythmogenic right ventricular cardiomyopathyMimount Bourfiss1, Niek Prakken2, Jeroen van der Heijden1, Ihab Kamel3, Stefan Zimmerman3, Folkert Asselbergs1,Tim Leiner1, Birgitta Velthuis1, Anneline te Riele1

1University Medical Center Utrecht, Utrecht, Netherlands, 2University Medical Center Groningen, Groningen,Netherlands, 3Johns Hopkins Hospital, Baltimore, United States

08.6 Abstract 07-13Validation of the SIEIRA score for risk stratification in Brugada syndromeJi-Jian Chow1, Momina Yazdani2, Sian Jones2, Kevin Leong1, Michael Koa-Wing2, David Lefroy2, Phang Boon Lim2,Nick Linton2, Fu Siong Ng1, Norman Qureshi2, Zachary Whinnett2, Nicholas Peters1, Prapa Kanagaratnam1, AmandaVarnava2

1Imperial College London, London, United Kingdom, 2Imperial College Healthcare NHS Trust, London, United Kingdom

MONDAY JUNE 17, 201910:30 AM - 12:00 PMROOM NOTRE DAMEAbstract Oral Session 9

Ventricular arrhythmias: from PVC’s to VFChairpersons: Noel Boyle (Los Angeles, USA), Jasbir Sra (Milwaukee, USA)

09.1 Abstract 01-11Gap junction modulation is a major determinant of the mechanism and organisation of ventricularfibrillation Balvinder Handa1, Xinyang Li1, Caroline Roney2, David Pitcher1, Rasheda Chowdhury1, Nicholas Peters1, Fu Siong Ng1

1Imperial College London, London, United Kingdom, 2Kings College, London, United Kingdom

09.2 Abstract 18-12 30

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Zigzag bipolar radiofrequency catheter ablation: a novel technique to achieve transmural lesions forelimination of ventricular arrhythmiasShingo Maeda1, Masahiko Goya2, Tasuku Yamamoto2, Masahiko Nakao2, Hirofumi Kujiraoka2, Kiko Akiyoshi2,Masahiro Sekigawa2, Atsuhiko Yagishita2, Yoshihide Takahashi 1, Mihoko Kawabata2, Kenzo Hirao2

1Advanced Arrhythmia Research, Tokyo Medical and Dental University, Tokyo, Japan, 2Department of CardiovascularMedicine, Tokyo Medical and Dental University, Tokyo, Japan

09.3 Abstract 07-14Ventricular conduction stability is a novel non-invasive measure of arrhythmic substrate which isreduced in idiopathic ventricular fibrillation survivorsJi-Jian Chow1, Kevin Leong1, Matthew Shun-Shin1, Michael Koa-Wing2, David Lefroy2, Phang Boon Lim2, Nick Linton1,Fu Siong Ng1, Norman Qureshi2, Zachary Whinnett2, Nicholas Peters1, Amanda Varnava2, Prapa Kanagaratnam1

1Imperial College London, London, United Kingdom, 2Imperial College Healthcare NHS Trust, London, United Kingdom

09.4 Abstract 18-15Machine learning successfully identifies ventricular ectopic foci from surface ECGsRohin K. Reddy1, Ahran D. Arnold1, James P. Howard1, Matthew J. Shun-Shin1, Ian J. Wright1, D. Wyn Davies1, PhangBoon Lim1, Michael Koa-Wing1, Norman Qureshi1, David C. Lefroy1, Fu Siong Ng1, Nicholas S. Peters1, Nick W. F.Linton1, Prapa Kanagaratnam1, Darrel P. Francis1, Zachary I. Whinnett11National Heart and Lung Institute, Imperial College London, London, United Kingdom

09.5 Abstract 17-13Barrier and facilitators to public access defibrillation in out-of-hospital cardiac arrest: the SorrentoPeninsula register Maurizio Santomauro1, Vincenzo Iaccarino2, Carla Riganti3, Mario Alberto Santomauro1, Raffaele Giordano1, GabrieleIannelli1, Francesco Elia1, Mario Petretta1, Domenico Bonaduce1

1Department of Cardiovascular Emergency, Internal Medicine, Geriatric, Azienda Universitaria Federico II Napoli,Napoli (NA), Italy, 2Department of Cardiology, Sorrento Hospital ASL NA3 Sud, Sorrento, Sorrento, Italy, 3Health BoardDirection, Azienda Ospedaliera Universitaria, Naples, Napoli (NA), Italy

09.6 Abstract 19-13Sudden cardiac death prediction in arrhythmogenic right ventricular cardiomyopathy (ARVC): atransatlantic multinational collaborationJulia Cadrin-Tourigny1, Laurens P Bosman2, Mimount Bourfiss2, Weijia Wang3, Rafik Tadros1, Aditya Bhonsale3, OyvindH Lie4, Ardan M Saguner5, Anneli Svensson6, Antoine Andorin1, Crystal Tichnell3, Brittney Murray3, Katja Zeppenfeld7,Maarten P van den Berg8, Folkert W Asselbergs2, Arthur A M Wilde9, Andrew D Krahn10, Mario Talajic1, Lena Rivard1,Stefan L Zimmerman3, Ihab R Kamel3, Jane E Crosson3, Daniel P Judge11, Sing-Chien Yap12, Jeroen F Van derHeijden13, Harikrishna Tandri3, Jan D.H Jongbloed8, Peter van Tintelen2, Pyotr G Platonov14, Firat Duru5, Kristina HHaugaa4, Paul Khairy1, Richard N W Hauer2, Hugh G Calkins3, Anneline S J M te Riele2, Cynthia A James3

1Montreal Heart Institute, Montreal, Canada, 2Netherlands Heart Institute, Utrecht, Netherlands, 3Johns HopkinsHospital, Baltimore, United States, 4Oslo University Hospital, Oslo, Norway, 5University Heart Center Zurich, Zurich,Switzerland, 6Linköping University, Linköping, Sweden, 7Leiden University Medical Center, Leiden, Netherlands,8University Medical Center Groningen, Groningen, Netherlands, 9Amsterdam UMC, University of Amsterdam,Amsterdam, Netherlands, 10University of British Columbia, Vancouver, Canada, 11Medical University of South Carolina,Charleston, United States, 12Erasmus Medical Center, Rotterdam, Netherlands, 13University Medical Center Utrecht,Utrecht, Netherlands, 14Lund University, Lund, Sweden

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MONDAY JUNE 17, 20192:00 PM - 3:30 PMROOM GRAND LARGESession SD-03

First EURA-ECAS Special Session Sudden death in Hypertrophic Cardiomyopathy (HCM)Chairpersons: Christine Albert (Boston, USA), Yurij Karpenko (Odessa, UA)

1. ICD for primary prevention of sudden death in hypertrophic cardiomyopathy David Cannom (Los Angeles, USA)

2. Prevention of sudden cardiac death after septal myectomy in HCMMark Estes III (Pittsburgh, USA)

3. Value of electrophysiologic testing in HCMAndrey Ardashev (Moscow, RU)

4. Prevention of stroke in patients with HCM and AFBrian Downey (Boston, USA)

MONDAY JUNE 17, 20192:00 PM - 3:30 PMROOM ESTAQUESession AF-04

Do we need antiarrhythmic drug therapy in the AF ablation era?Chairpersons: Nils Edvardsson (Goteborg, SE), Alessandro Capucci (Ancona, IT)

1. Antiarrhythmic drugs for termination of recent onset atrial fibrillation Alessandro Capucci (Ancona, IT)

Room EUGENIE 12 :00 PM - 1:45 PM

Luncheon SymposiumSupported by and educational grant of ACUTUS Medical Inc

Biatrial Mapping Techniques: Advances in Technology and their potential role inUnderstanding Arrhythmia Mechanisms and Therapy

Chairpersons: Dipen Shah (Geneva, CH), Samuel Levy (Marseille, FR)

1. Simultaneous Biatrial mapping and Imaging: Development and Mechanistic InsightsSanjeev Saksena MD (Warren, NJ, USA)

2. Prospective Randomized Comparison Of Rotor Ablation Vs Conventional Ablation For TreatmentOf Persistent Atrial Fibrillation - The REAFFIRM Trial. Johannes Brachmann MD, (Coburg, DE)

3. Insights into biatrial mechanisms of atrial fibrillation - early experience of AcQmapsimultaneous biatrial mapping. Michael Pope, MD (University of Cambridge, Cambridge, GB)

Panel discussion with audience

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2. Use of antiarrhythmic therapy before and after electrical cardioversionJuan Tamargo (Madrid, ES)

3. Antiarrhythmic treatment for prevention of AF recurrencesSamuel Lévy (Marseille, FR)

4. Short-term use of antiarrhythmic drug therapy after catheter ablation (The East-AF Trial)Kasuaki Kaitani (Tenri, JP)

MONDAY JUNE 17, 20192:00 PM - 3:30 PMROOM JOLIETTESession WS-09

A tribute to Arthur Moss, MD in Memoriam

ICD therapy in 2019: Is it time to alter current device selection criteria Introduction: Arthur Moss, MD A giant in the Fight against sudden death (5min), David Cannom (Los Angeles, USA)

Chairpersons: Massimo Santini (Rome, IT), David Cannom (Los Angeles, USA)

1. LV ejection fraction: The legacy of an AVID substudy evolving to present day role in sudden deathrisk stratificationSanjeev Saksena (Warren, USA)

2. Biomarkers to identify patients at risk for sudden cardiac deathWerner Jung (Villingen, DE)

3. Genetics and risk of sudden death in risk stratification models Stefan Kaab (Munich, DE)

4. Multimodal approach of risk stratification of sudden cardiac deathPhilippe Chevalier (Lyon, France)

MONDAY JUNE 17, 20192:00 PM - 3:30 PMROOM SAINT JEANSession SP-12

Special Session HRS-ECAS ITwo decades of arrhythmogenic cardiomyopathy (ACM) research: New insights intodiagnosis and treatmentChairpersons: Richard Hauer (Utrecht, NL), Frank Marcus (Tucson, USA)

1. Critical appraisal of the 2010 Task Force criteriaDomenico Corrado (Padua, IT)

2. Use of auto-antibodies for identification of ACMFirat Duru (Zurich, CH)

3. Role of catheter ablation in ACMHugh Calkins (Baltimore, USA)

4. Arrhythmogenic cardiomyopathy: The Chinese experienceJiangping Song (Beijing, CN)

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MONDAY JUNE 17, 20192:00 PM - 3:30 PMROOM MUCEMSession SP-13

Atrial fibrillation management after pivotal clinical trials: the dilemmas Supported by an educational grant from Bayer AG

Chairpersons: Thorsten Lewalter (Munich, DE), Luc De Roy (Louvain, BE)

1. Should there be changes in the practice guidelines beyond the existing recommendations John Camm (London, GB)

2. Should all patients with atrial fibrillation and systolic ventricular dysfunction be considered forcatheter ablation as first line therapy Ernst Vester (Dusseldorf, DE)

3. Patients with highly symptomatic palpitations regardless of age should be offered AF ablation asfirst line optionPrapa Kanagaratnam (London, GB)

4. All catheter ablation procedures in AF are created equal as long as they include pulmonary veinisolation Andrea Natale ( Austin, USA)

MONDAY JUNE 17, 20192:00 PM - 3:30 PMROOM NOTRE DAMESession SP-14

Revisiting cardiac pacing in 2019: New insights into pathophysiology will lead toimproved pacing therapiesChairpersons: Jeanne Poole (Seattle, USA), Luca Santini (Rome, IT)

1. His Bundle pacing : what the past and present teach us about its physiologic effects Bengt Herweg (Tampa, USA)

2. The clinical role of His Bundle pacing in heart failure with intraventricular conduction defectsPugazhendhi Vijayaraman (Wilkes Barre, USA)

3. Fibrillation prevention and therapy algorithms: Do they belong in all bradycardia and tachycardiadevices?TBA

4. Is it time for mechanical physiologic benefits of multisite pacing modes to be tested in upstreamtherapy for heart failure and arrhythmia prevention? Sanjeev Saksena (Warren, USA)

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MONDAY JUNE 17, 20192:00 PM - 3:30 PMROOM LACYDONChaired Poster session DPosters displayed from 2:00 PM to 5:00 PMPresenters and Chairpersons presents from 2:00 PM to 3:30 AM

Mechanisms and detection of atrial fibrillation & management of atrial fibrillation or/andatrial flutterChairpersons: Roger Winkle (Palo Alto, USA), Fu Siong Ng (London, GB)

14.27 Abstract 15-22Risk factors and time distribution of recurrence in patients with atrial fibrillationAntoniya Kisheva1, Yoto Yotov1, Trifon Chervenkov1

1Medical University Varna, Varna, Bulgaria

14-28 Abstract 15-20Does the oral anticoagulant usage impact the health-related quality of life for atrial fibrillationpatients over 6 and 12-month period?Ketija Apsite1, Diana Stoldere1, Andris Tupahins1, Toms Janis Eglitis1, Nikolajs Nesterovics1, Tarass Ivascenko1,Vladimirs Voicehovskis1, Oskars Kalejs1, Aivars Lejnieks1

1Riga Stradins University, Riga, Latvia

14.29 Abstract 15-14Incidence of left atrial appendage thrombus in patients with hypertrophic cardiomyopathy and non-valvular atrial fibrillation Jing Cui1, Xin Du1, Jia-Hui Wu1, Jian-Zeng Dong1, Chang-Sheng Ma1

1Cardiology Center of Beijing Anzhen Hospital, Beijing, China

14.30 Abstract 28-16The utility of minielecrode-based technology on the identification of gap in isthmus-dependent atrialflutter redo procedures: a case report Giammarco Schiaffini Carlo Lavalle1

1Policlinico Umberto I - Università “Sapienza” di Roma, Rome, Italy

14.31 Abstract 18-16Preventive block of the cavitricuspid isthmus in the interventional treatment of atrial fibrillationNikita Safonov1, Fajbushevich Alexander1, Olga Safonova1, Mezentsev Pavel1, Shidlovskaia Svetlana2, MaximkinDaniil11Peoples friendship university of Russia, Moscow, Russia, 2I.M. Sechenov First Moscow State Medical University,Moscow, Russia

Mechanisms and detection of atrial fibrillation14.32 Abstract 15-19Hospitalization frequencies among high-risk non-valvular atrial fibrillation patientsKetija Apsite1, Diana Stoldere1, Toms Janis Eglitis1, Andris Tupahins1, Irina Pupkevica1, Katrina Pukite 1, KristineJubele1, Aivars Lejnieks1, Oskars Kalejs1

1Riga Stradins University, Riga, Latvia

14.33 Abstract 15-31Noninvasive low level vagus nerve stimulation to suppress atrial fibrillation: a randomized clinical trialStavros Stavrakis1, Julie Stoner1, Mary Beth Humphrey1, Benjamin Scherlag1, Warren Jackman1, Sunny Po1

1University of Oklahoma Health Sciences Center, Oklahoma City, United States

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MONDAY JUNE 17, 2019

14.34 Abstract 15-30Screening atrial fibrillation using machine learningJean-Marie Gregoire1, Nik Subramanian2, David Papazian2, Hugues Bersini31Independent Cardiologist, Brussels, Belgium, 2Kantify, Brussels, Belgium, 3IRIDIA Lab, Universite Libre de Bruxelles,Brussels, Belgium

14.35 Abstract 15-29The risk factors relating with newly development of atrial fibrillation in the non-elderly adults: resultsfrom 25 years periodical health examinationAi Ozawa1, Seiichiro Matsuo2, Keiichi Inada1, Hidetaka Nagasawa1

1Nagasawa Clinic, Tokyo, Japan, 2The Jikei University School of Medicine Katsushika Medical Center, Tokyo, Japan

14. 36 Abstract 14-10Temporal trends and factors associated with increased mortality among atrial fibrillation weekendhospitalizations. An insight from national inpatient sample 2005-2014. Dinesh Voruganti1, Ghanshyam Shantha2, Sushma Dugyala3, Naga Venkata Krishna Pothineni4, Ala Mohsen5,Abhishek Deshmukh6, Deobrat Chandra Mallick7, Amgad Mentias1, Stephanie Colello8, Rakesh Latchamsetty2, KritJongnarangsin2, Mohammed Saeed2, Frank Pelosi2, Ryan Carnahan1, Michael Giudici11University of Iowa, Iowa City, United States, University of Michigan, Ann Arbor, United States, 3University of Alabama,Tuscaloosa, United States, 4University of Arkansas, Little Rock, United States, 5Louisiana State University, NewOrleans, United States, 6Mayo Clinic, Rochester, Sweden, 7Spohn Shoreline Hospital, Corpus Christi, United States,8Hospital of the University of Pennsylvania, Philadelphia, United States

MONDAY JUNE 17, 20194:00 PM - 5:30 PMROOM GRAND LARGESession SD-04

Management of inherited potentially lethal arrhythmia syndromesChairpersons: Xavier Jouven (Paris, FR), Stefan Kaab (Munich, DE)

1. Long QT syndromePeter Schwartz (Milan, IT)

2. Catecholaminergic polymorphic ventricular tachycardiaFrank Marcus (Tucson, USA)

3. Early repolarisation syndromeStefan Kaab (Munich, DE)

4. Short QTFiorenzo Gaita (Torino, IT)

3:30 PM - 4:00 PMPHAR Club Fist floor Coffee break and visit to posters Room Lacydon

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MONDAY JUNE 17, 2019

MONDAY JUNE 17, 20194:00 PM - 5:30 PMROOM ESTAQUESession AF-05

Atrial fibrillation meets neurologySupported by an educational grant from Bayer AG

Chairpersons: Heidi Estner (Munich, DE), Soeren Z. Diederichsen, (Copenhagen, DK)

1. Secondary stroke prevention in embolic stroke of undetermined source (ESUS) – always go for animplanted loop recorder?Tamas Szili-Torok (Rotterdam, NL)

2. LAA occluder – always close the ear?Luigi Di Biase (New-York, USA)

3. Atrial High Rate Episodes (AHRE) – always go for anticoagulation?Michael Näbauer (Munich, DE)

MONDAY JUNE 17, 20194:00 PM - 5:30 PM ROOM JOLIETTESession SP-16

Special Session HRS-ECAS IIThe physician’s dilemma: Accurate prediction of sudden death in arrhythmogeniccardiomyopathy (ACM)Chairpersons: Hugh Calkins (Baltimore, USA), Richard Hauer (Utrecht, NL)

1. Use of advanced imaging techniques in arrhythmic risk stratification of ACMAnneline te Riele (Utrecht, NL)

2. Towards personalized risk assessment in ACMCindy James (Baltimore, USA)

3. Debate: Can ACM lead to sudden death in a structurally normal heart?Protagonist : Mario Delmar (New York, USA) Antagonist: Cristina Basso (Padua, IT)

MONDAY JUNE 17, 20194:00 PM - 5:30 PMROOM SAINT JEANSession SP-17Supported by an educational grant from Bayer AG

Personalized medicine and AF: will it ever happens?Chairpersons: Leonardo Calò (Rome, IT), Mark Estes (Pittsburg, USA)

1. In the context of 2 decades of progress do we need a new AF classification?Samuel Levy (Marseille, FR)

2. AF MechanismsDobromir Dobrev (Essen, DE)

3. Rhythm controlAndrea Natale (Austin, USA)

4. Stroke preventionRiccardo Cappato (Milan, IT)

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MONDAY JUNE 17, 2019

MONDAY JUNE 17, 20194:00 PM - 5:30 PMROOM MUCEMSession WS-08

ECG interpretation course (Part 2): Complex arrhythmias (Case-studies)A tribute to Ralph Lazzara in Memoriam

Introduction: Warren Jackman (Oklahoma City, USA) (5min)

Chairpersons: John Camm (London, GB), Jean-Jacques Blanc (Brest, FR)

1. Differential diagnosis of narrow QRS complex tachycardiasTBA

2. Differential diagnosis of wide QRS complex tachycardiasRobert Franck (Paris, FR)

3. Tachycardias in the preexcitation syndromesLeonardo Calo (Rome, IT)

MONDAY JUNE 17, 20195:30 PM - 6:15 PMROOM GRAND LARGEDebate 1

First PV Isolation should be performed with a cryoballoonChairpersons: Edward Rowland (London, GB), Ellen Hoffmann (Munich, DE)

Protagonist: Karl-Heinz Kuck (Hamburg, DE)

Antagonist: Dipen Shah (Geneva, CH)

MONDAY JUNE 17, 20195:30 PM - 6:15 PMROOM JOLIETTEDebate 2

Non-pharmacologic therapy has no role in heart failure with preserved ejection fraction Chairpersons: John A. Camm (London, GB), Luis Molina (Mexico City, MX)

Protagonist: Christian Torp-Pedersen (Copenhagen, DK)

Antagonist: Sanjeev Saksena (Warren, USA)

MONDAY JUNE 17, 20195:30 PM - 6:15 PMROOM MUCEMDebate 3

Sudden death prophylaxis in nonischemic cardiomyopathy: The role of implantabledefibrillators should be removed from the guidelines Chairpersons: Robert Hauser (Minneapolis, USA), Bharat Kantharia (New-York, USA)

Protagonist: Jean-Jacques Blanc (Brest, FR)

Antagonist: Bruce Wilkoff (Cleveland, USA)

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TUESDAY JUNE 18, 2019

MONDAY JUNE 17, 20195:30 PM - 6:15 PMROOM SAINT JEANDebate 4

PVI should be 1st line therapy in all symptomatic AF patientsChairpersons: Riccardo Cappato (Milan, IT), Gilles Lascault (Paris, FR)

Protagonist: Walid Saliba (Cleveland, USA)

Antagonist: Mark Estes (Pittsburg, USA)

6:15PM-7:00PMROOM GRAND LARGE

Special Lecture: Mark Josephson, MD in Memoriam By

Recent Developpements in Arrhythmogenic Cardiomyopathy

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Mark N. Estes III, MD (Boston, USA)

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TUESDAY JUNE 18, 2019

TUESDAY JUNE 18, 20198:30 AM - 10:00 AMROOM GRAND LARGEAbstract Oral Session 10

Mechanisms of cardiac arrhythmiasChairpersons: Magdi Sami (Montreal, CA), Dobromir Dobrev (Essen, DE)

10.1 Abstract 14-15Immune privilege may predispose patients after heart transplantation to develop recipient to donoratrial connections predisposing to atrial arrhythmiasBengt Herweg1, Madhan Nellaiyappan1, Thanh Tran1, George Mabry1, Kathryn Weston1, and Mark Weston1

1University of South Florida Morsani College of Medicine and Tampa General Hospital, Tampa, FL.

10.2 Abstract 01-14Electrogram morphology and substrate size but not conduction velocities are pro-fibrillatory markersin an in vitro modelAngeliki Iakovou1, Konstantinos Tzortzis1, Chris Cantwell1, Nicholas Peters1, Rasheda Chowdhury1

1Imperial College London, London, United Kingdom

10.3 Abstract 15-213D multimodal atlas to quantify termination sites for persistent atrial fibrillation Albert Rogers1, Nosheen Moosvi1, Mahmood Alhusseini1, Tina Baykaner1, Mintu Turakhia1, Chad Brodt1, Paul Wang1,Wouter-Jan Rappel2, Paul Clopton1, Sanjiv Narayan1

1Stanford University, Stanford, United States, 2UC San Diego, La Jolla, United States

10.4 Abstract 01-10The degree and spatial distribution of myocardial fibrosis can influence the underlyingmechanism of ventricular fibrillationBalvinder Handa1, Xinyang Li1, Catherine Mansfield1, Richard Jabbour1, David Pitcher1, Rasheda Chowdhury1,Nicholas Peters1, Fu Siong Ng1

1Imperial College London, London, United Kingdom

10.5 Abstract 01-12Search for local conduction delay in patients with atrial fibrillationElena Artyukhina1, Amiran Revishvili1, Maxim Yshkov1, Vitaly Kalinin2

1Institute of Surgery named after A.V.Vishnevsky, Moscow, Russia, 2EP Solution SA, Switzerland, Switzerland

TUESDAY JUNE 18, 20198:30 AM - 10:00 AMROOM ESTAQUEAbstract Oral Session 11

Cardiac pacing and CRTChairpersons: Gerhard Steinbeck (Munich, DE), Bharat Kantharia (New York, USA)

11.1 Abstract 31-11Outcomes of atrial resynchronization therapy in patients with paroxysmal and persistent atrialfibrillation and heart failure with preserved and reduced ejection fractionSanjeev Saksena1, April Slee1, Marwan Saad1

1Electrophysiology Research Foundation, Warren, United States

11.2 Abstract 23-13Efficacy and safety related to cardiac lead extraction with different techniques: 17-years single centreexperiencePiro Agostino1, Carlo Lavalle2, Marco Valerio Mariani1, Giuseppe Giunta2, Maria Chiara Gatto2, Antonio Ciccaglioni1,Francesco Fedele1

1University or Rome “Sapienza”, Rome, Italy, 2Policlinico Umberto I, Rome, Italy

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TUESDAY JUNE 18, 2019

11.3 Abstract 22-10The utility of leadless pacemaker’s implantation under intracardiac echocardiography guidanceHiroki Takahashi1, Masahiko Takagi1, Takuro Yoshio1, Masue Yoh1, Ichiro shiojima1

1Department of Medicine II, Kansai Medical University, Moriguchi, Japan

11.4 Abstract 19-12Calcification of endotak ICD leads: clinical significance and need for surveillanceRobert Hauser1

1Minneapolis Heart Institute Foundation, Minneapolis, United States

11.5 Abstract 17-12Does amiodarone reduce the effectiveness of antitachycardia pacing in patients with implantablecardioverters/defibrillators?Dalia Giedrimiene1, Joshua W Harrison2, Lane Duvall2, Jeffrey Kluger2

1University of Saint Joseph/Hartford Hospital, West Hartford, United States, 2Hartford Hospital, Hartford HealthCare,Hartford, United States

11.6 Abstract 23-12Seasonal and circadian distribution and atrial antitachycardia pacing for atrial fibrillation in patientswith cardiac implantable electrophysiological devicesShingo Maeda1, Yoshihide Takahashi1, Tasuku Yamamoto2, Hirofumi Kujiraoka2, Masahiko Nakao2, Kiko Akiyoshi2,Masahiro Sekigawa2, Susumu Tao2, Atsuhiko Yagishita2, Mihoko Kawabata2, Masahiko Goya2, Kenzo Hirao2

1Advanced Arrhythmia Research, Tokyo Medical and Dental University, Tokyo, Japan, 2Department of CardiovascularMedicine, Tokyo Medical and Dental University, Tokyo, Japan

TUESDAY JUNE 18, 201908:30 AM - 10:00 AM

ROOM JOLIETTEAbstract Oral Session 12

Mapping of atrial and ventricular arrhythmiasChairpersons: Ernst Vester (Düsseldorf, DE), Reza Wakili (Essen, DE)

12.1 Abstract 14-12Clinical & computational study of a new multi-position, non-contact method for full-chamber, ultra-high-density maps of stable atrial arrhythmiasJunaid Zaman1, Min Zhu2, Pratik Shah2, Nathan Angel2, Xinwei Shi2, Derrick Chou2, Xunzhang Wang3, ChristophScharf4, Munmohan Virdee1, Andrew Grace1

1Royal Papworth Hospital, Cambridge, United Kingdom, 2Acutus Medical, Carlsbad, United States, 3Cedars SinaiMedical Center, Los Angeles, United States, 4Cardiovascular Center, Zurich, Switzerland

12.2 Abstract 17-11High density mapping of dynamic functional late potentials and functional late repolarization identifiescritical sites for ablation in ventricular tachycardia.Neil Srinivasan1, Jason Garcia1, Richard Schilling1, Syed Ahsan1, Mehul Dhinoja1, Richard Ang1, Mark Earley1, MartinLowe1, Anthony Chow1, Pier Lambiase1

1Barts Heart Centre, London, United Kingdom

12.3 Abstract 18-19Perimitral atrial flutter: mapping the tachycardia supporting isthmus to guide ablation. George Katritsis1, Vishal Luther1, Nick Linton1, Mike Koa-Wing1, Norman Qureshi1, Fu Siong Ng1, Boon Lim1, ZacharyWhinnet1, David Lefroy1, Nicholas Peters1, Prapa Kanagaratnam1

1Department of Cardiology, Hammersmith Hospital, Imperial College Healthcare NHS Trust, Lomdon, United Kingdom

12.4 Abstract 15-12Use of a novel algorithm ‘RETRO-mapping’ to map focal activation in persistent atrial fibrillationClare Coyle1, Ian Mann1, Nicholas Linton1, Ji-jian Chow1, Norman Qureshi1, Michael Koa-Wing1, Zachary Whinnett1,Boon Lim1, Darrel Francis1, Nicholas Peters1, Prapa Kanagaratnam1

1Imperial College, London, United Kingdom

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TUESDAY JUNE 18, 2019

12.5 Abstract 28-17High resolution 3D mapping of the his region to facilitate permanent His bundle lead placement, AVjunctional ablation and bundle branch recruitmentBengt Herweg, David R. Wilson, Nicholas Kotch, Anant Kharod, Allen Welter-Frost, Chris Cook, Thanh Tran,Pugazhendhi VijayaramanUniversity of South Florida Morsani College of Medicine, Tampa, FL, James A Haley VA Hospital, Tampa, FL,University of South Florida, Tampa, FL, Geisinger Heart Institute, Wilkes- Barre, PA

12.6 Abstract 05-10Noninvasive imaging of cardiac arrhythmiasMikhail Khlynin1, Roman Batalov1, Stanislav Usenkov1, Evgeniy Archakov1, Tariel Atabekov1, Sergey Popov1

1Cardiology Research Institute of Tomsk National Research Medical Center, Tomsk, Russia

TUESDAY JUNE 18, 201910:30 AM - 12:00 PM ROOM GRAND LARGESession SP-19

Pacing management of bradyarrhythmias - Beyond the Guidelines Chairpersons: David G Benditt (Minneapolis, USA), Luca Santini (Rome, IT)

1. Can carotid sinus hypersensitivity ever be an indication for pacing?Steve Parry (Newcastle, GB)

2. Mobitz type 1 block in the elderly: A possible pacing Indication?Richard Sutton (Monaco, MC)

3. When is pacing appropriate in vasovagal syncope?Brian Olshansky (Iowa City, USA)

4. Leadless cardiac pacemakers for bradyarrhythmiasWerner Jung (Villingen, DE)

TUESDAY JUNE 18, 201910:30 AM - 12:00 PMROOM ESTAQUESession SP-20

New tools and mapping for ablationChairpersons: Daniel Steven (Cologne, DE), Shlomo Ben-Haim (London-GB)

1. High-Power Short-duration for AF ablationRoger Winkle (Palo Alto, USA)

2. Dipole density mapping (ACUTUS™) in persistent AFTom Wong (London GB)

3. Real-time local impedance measurement Reza Wakili (Essen, DE)

4. Real-time wide band di-electric sensing system (KODEX-EPD™) Andreas Rillig (Novosibirsk, RU)

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TUESDAY JUNE 18, 2019

TUESDAY JUNE 18, 201910:30 AM - 12:00 PMROOM JOLIETTESession SP-21

Mapping and ablation of scar related VTChairpersons: Gerhard Steinbeck (Munich, DE), Magdi Sami (Montreal, CA)

1. High- density Mapping improves outcomes of VT ablationTBA

2. Substrate imaging is mandatory in scar related VT ablationElena Ene (Bad Neustadt, DE)

3. Substrate homogenization: All you can reachJose Merino (Madrid, ES)

4. Are the guidelines on VT ablation still adequate?Magdi Sami (Montreal, CA)

TUESDAY JUNE 18, 201910:30 AM - 12:00 PMROOM SAINT JEANSession SP-22

Non-Pharmacological management of heart failure: What is new?Chairpersons: Robert Hauser (Minneapolis, USA), Ernst Vester (Dusseldorf, DE)

1. What’s new in patient selection for heart failure devices?Bharat Kantharia (New-York, USA)

2. What’s new in LV electrodes and their placement?Francesco Zanon (Rovigo, IT)

3. What’s new in heart failure device programming to optimize function, at implant, post implant andbeat-to-beat?Robert Hauser (Minneapolis, USA)

4. Cardiac contractility modulation (CCM) therapy: Does it work? How does it work? Where does itfit with other heart failure device management?Neil Sulke (Eastbourne, GB)

TUESDAY JUNE 18, 201910:30 AM - 12:00 PMROOM MUCEMSession SP-23

Atrial fibrillation: emerging risk factorsSupported by an educational grant from Bayer AGChairpersons : Alessandro Capucci (Ancona, IT), Luis Molina (Mexico City, MX)

1. ObesityPromund Obel (Johannesburg, ZA)

2. Obstructive sleep apnea syndromeAdam S Fein (Boston, USA)

3. Sports activityFrancesco Furlanello (Milan, IT)

4. Food and antioxidationLeonardo Calò (Rome, IT)

12:00 PM - 12:30 PM BEST POSTER AWARDS Room GRAND LARGE

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THANK YOU FOR ATTENDING ECAS 2019 IN MARSEILLEAND FOR YOUR CONTINUED SUPPORT TO

THE EUROPEAN CARDIAC ARRHYTHMIA SOCIETY.WE HOPE THE CONGRESS MET YOUR GOALS AND EXPECTATION

AND WE HOPE TO SEE YOU NEXT YEAR FOR ECAS 2020