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This is a work in progress!
Subject to change in content and points offered for each section!
Further discussion in class will clarify details!
PROJECT DUE DATE AND PRESENTATION:FRIDAY, OCTOBER 24TH.
Biobank Brochure
~rubric and example
PROJECT DUE DATE AND PRESENTATION:FRIDAY, OCTOBER 24TH.
Additional Information:
Amy Albritton
Honor’s Anatomy and PhysiologyPrattville High SchoolApril 4, 2014
[email protected] (adrenoleukodystrophy)
Lorenzo’s Oil Refinery
“a bootleg company”
ALD
• http://ghr.nlm.nih.gov/search?query• http://omim.org/entry/300100• http://www.childrenscancer.org
• behavioral changes
• poor memory and poor school performance
• visual loss, seizures, deafness
• difficulties with speechswallowing and coordination
• Fecal and urinary incontinence
• Cerebral demyelination and inflammation
SYMPTOMS
Contact Information
Click icon to add picture
PAGE 3 (Cover Page)PAGE 2 (Back of
Brochure)
PAGE 1
Click icon to add picture
Click icon to add picture
Front side of sheet…
I. Page 1 (Front Side of Sheet): a. Bullet these. List reasons
WHY someone should choose this biobank.b. Pictures (at least three)
II. Page 2: Back of Brochure: (Front Side of Sheet):
1. Additional Resources:
This is where you will list your sources for pictures, ideas, text, quote Must have at least three.
One source must be your satisfied customer for thetestimonial quote/short story.
Write them using MLA citation format
2. Contact Information:
a.) Your name
b.) Honor’s Genetics
c.) Period
d.) Prattville High School
e.) Date
III. Page 3: Front Cover of Brochure: (Front Side of Sheet)
a. Name of facility, center, or program
b. “Slogan”
c. Logo
d. Picture/artwork
Front side of sheet…
PAGE 1 PAGE 3 PAGE 2
• affects all ethnic groups • most common inherited leukodystrophy• minimum incidence ranging from 1:42,000• untreated, ALD will cause death in three to five
years• progression can be stabilized• no cure yet
Our ResearchTreatment Plan:
What does it do to the
CNS?
• mutation in the ABCD1 gene
What causes ALD?
• X-linked recessive genetic disorder that affects males.• ‘adreno’ refers to the adrenal glands; ‘leuko’ refers to the white matter of the brain, and ‘dystrophy’ means abnormal growth or development.• A peroxisomal disease
• damages the myelin sheath on neurons• no production of protein that helps break down fatty acids• accumulation of the saturated very long chain fatty acids in all body tissues.
What is Adrenoleukodystrophy? • bone marrow
transplant
• intravenous mesenchymal stem cells during the period before the transplant
• high-dose antioxidant therapy• provide families with emotional
support, networking opportunities, and other kinds of assistance
• Adrenal steroid replacement therapy
• Hematopoietic stem cell transplantation
• gene therapy• allogeneic hematopoietic stem cell
transplantation (HSCT)“When we found out that all three of our boys, Owen, Dylan and Jacob, had it, we were devastated.” Darlene, mother of the boys
PAGE4 PAGE 5 PAGE 6
Click icon to add picture
PAGE 6PAGE 5PAGE 4
Click icon to add picture
Click icon to add picture
Back side of sheet…
PAGE 4 PAGE 6PAGE 5
Back side of sheeT
Requirements
IV. Page 4 (Back of Sheet):
a. What is a biobank?
b. 5 Requirements to be a legitimate biobank……. (bullet these)
c. Why do we need a biobank?
d. Pictures
e. Describe the process of using/making use of the biobank? (scientific explanation)
V. Page 5 (Back Side of Sheet):
a. Our Services Offered -Bullet these and describe. Stick to the most common.
b. Pictures/artwork-(of options- equipment, indiv. items, diagrams, artwork)
VI. Page 6 (Back Side of Sheet):
a. The Research - the following are suggestions……… Bullet these
• % of population represented in database • #1 service requested • #1 method of extracting target cells and tissues • Side effects or warnings of procedures • Possibility of a Cure for genetic disorders?• Names of disorders biobank is concerned with…. bullet
b. Pictures (at least two)
c. Testimonial/Quote/Short story
Personal Testimony/Quote/short story from satisfied customer
Picture- (person giving testimony/quote/story)
PROJECT DUE DATE AND PRESENTATION:FRIDAY, OCTOBER 24TH.