Thirteenth European Meeting on Hypertension Milan (Italy ...THIRTEENTH EUROPEAN MEETING ON HYPERTENSION 111 Thirteenth European Meeting on Hypertension Milan (Italy), June 13 / 17,

THIRTEENTH EUROPEAN MEETING ON HYPERTENSION 111

Thirteenth European Meeting on HypertensionMilan (Italy), June 13 / 17, 2003

7.15-8.15 Breakfast Workshop

Can computer assist in the clinical management of hypertension?

ChairmanE. O’Brien (Dublin, Ireland)

IntroductionE. O’Brien (Dublin, Ireland)

Can computers help in communicating with hypertensive patients?T. Pickering (New York, NY, USA)

Can computer programs simplify interpretation of ABPM?E. O’Brien (Dublin, Ireland)

Red Hall 1

Sunday, June 15

112 THIRTEENTH EUROPEAN MEETING ON HYPERTENSION



Assessment of cardiac structure in hypertension

ChairmanE. Agabiti-Rosei (Brescia, Italy)

Methods of evaluation of cardiac fibrosisG. De Simone (Naples, Italy)

Relation between cardiac structure and functionJ. Diez (Pamplona, Spain)

Red Hall 2

Sunday, June 15




Assessment of global cardiovascular risk. Advantages and disadvantages of various methods

ChairmanR. Cifkova (Prague, Czech Republic)

Framingham Risk Chart and the SCORE project.1999 WHO-ISH and 2003 ESH-ESC guidelines risk estimationR. Cifkova (Prague, Czech Republic)

Assessment of target organ damageM.L. Muiesan (Brescia, Italy)

Blue Hall

Sunday, June 15




Recent advantages in aldosterone antagonism

ChairmanA. Morganti (Milan, Italy)

Mechanisms of aldosterone mediated organ damageA.D. Struthers (Dundee, UK)

Clinical experience with the new aldosterone antagonist eplerenoneF. Zannad (Dommartin-lès-Toul, France)

Yellow Hall

Sunday, June 15


Diabetes and ObesityOral Session 4A


ChairmenR. Garcia-Robles (Madrid, Spain)S. Kjeldsen (Oslo, Norway)

8.30 Ambulatory blood pressure and heart rate variability - a prospective 6-year observation of youngtype 1 diabeticsP. Kruszewski, L. Bieniaszewski, B. Wolnik, E. Swierblewska, K. Kunicka, J. Neubauer-Geryk, B. Wyrzykowski (Gdansk, Poland)

8.45 Evidence for increased oxidative stress in the renal vasculature of patients with type 2 diabetesC. Delles, M.P. Schneider, S. Oehmer, S. John, I. Fleischmann, R.E. Schmieder (Erlangen, Germany)

9.00 Ultrasound tissue characterization in hypertensive patients with type 2 diabetes mellitusM.L. Muiesan, M. Salvetti, C. Monteduro, B. Bonzi, E. Porteri, P. Poisa, A. Paini, S. Viola, D. Rizzoni,E. Agabiti-Rosei (Brescia, Italy)

9.15 Appearance of renal damage in metabolic syndrome is preceded by glucose metabolismdisturbancesJ. Segura, C. Campo, C. Roldán, L. Fernández, L. Guerrero, R. García-Robles, J.L. Rodicio, L.M. Ruilope (Madrid, Spain)

9.30 Metabolic responses to interstitial angiotensin II in normal weight and obese menM. Boschmann, F. Adams, A.M. Sharma, F.C. Luft, J. Jordan (Berlin, Germany)

9.45 Renal sympathoactivation to insulin is mediated by melanocortin-4 receptorsK. Rahmouni, D.A. Morgan, W.G. Haynes (Iowa City, IA, USA)

10.00 Blood pressure and body weight in Ashanti, West AfricaF.P. Cappuccio, L. Emmett, F.B. Micah*, S.M. Kerry, J. Plange-Rhule*, J.B. Eastwood (London, UKand *Kumasi, Ghana)

10.15 The PPAR agonist pioglitazone increases plasma renin activity independently of sodium intakeand blood pressure in normal subjectsA. Zanchi, J. Nussberger, M. Maillard, M. Burnier (Lausanne, Switzerland)

Blue Hall

Sunday, June 15


Blood VesselsOral Session 4B


ChairmenH.R. Brunner (Lausanne, Switzerland)G. London (Paris, France)

8.30 Gestational age and birth weight in relation to aortic stiffness in healthy young adults: two separate mechanisms?M. Bots, A. Oren, L. Vos, W. Bos*, M. Safar**, D. Grobbee, C. Uiterwaal (Utrecht and *Nieuwegein,The Netherlands; **Paris, France)

8.45 Gender differences in large artery stiffness pre- and post-pubertyA. Ahimastos, M. Formosa, A. Dart, B. Kingwell (Melbourne, Australia)

9.00 Ethnic differences in aortic stiffness in healthy normotensivesB. Muchanga, D. Diogo, A. Damasceno, J. Maldonado*, R. Asmar**, J.A. Silva*, J. Polonia*,(Maputo, Mozambique; *Matosinhos, Portugal; **Paris, France)

9.15 Wall stress of the abdominal aorta in man - Studies in vivo using ultrasound technique andcontinuum mechanical approachH. Åstrand, J. Stålhand, M. Karlsson, T. Länne (Linköping, Sweden)

9.30 Confounding effects of heart rate on pulse wave velocity assessment in paced patients with lowdegree of atherosclerosisE. Haesler, X. Lyon, E. Pruvot, D. Hayoz (Lausanne, Switzerland)

9.45 Arterial stiffness, wave reflections and the risk for coronary artery diseaseT. Weber, J. Auer, M.F. O´Rourke*, R. Berent, E. Lassnig, B. Eber (Wels, Austria; *Sydney, Australia)

10.00 The impact of 24-h blood pressure on carotid artery distensibility and pulse wave velocity in ageneral population: data from the PAMELA II studyC. Giannattasio, L. Boffi, D. Corsi, M. Failla, R. Facchetti, H. Paul-O-Fritz**, L. Beltrame, M. Bombelli,R. Sega**, G. Mancia* (Monza, *Milan and **Vimercate, Italy)

10.30 Inflammation and cardiovascular therapy in end-stage renal diseaseG.M. London, A.P. Guerin, B.M. Pannier, S.J. Marchais (Fleury-Merogis, France)

Red Hall 1

Sunday, June 15


Genetics and MolecularBiologyOral Session 4C


ChairmenG. Bianchi (Milan, Italy)T. Unger (Berlin, Germany)

8.30 Investigation of rat Y chromosome structure and its contribution to cardiovascular phenotypesP. Strahorn, B. Champagne, D. Graham, F.J. Charchar, A.F. Dominiczak (Glasgow, UK)

8.45 Interaction between the Y chromosome and blood pressure loci on rat chromosome 2D. Graham, N. Anderson, M.W. McBride, P. Strahorn, B. Champagne, F. Charchar, A.F. Dominiczak(Glasgow, UK)

9.00 Low intracellular body water, redistribution of body fat, decreased Na transporters and absenceof insulin resistance: identification and genetic determinants of a novel hypertensive syndromeP. Hamet, O. Seda, D. Gaudet**, R. Wang, S. Orlov, Z. Pausova, E. Lander***, T.J. Hudson***, A.W. Cowley*, J. Tremblay (Montreal, Canada; *Milwaukee, USA; **Chicoutimi, Canada;***Cambridge, USA)

9.15 Functional role of beta adducin in the progression of proteinuria in congenic rats from the Milanstrain and in beta adducin null miceM. Ferrandi, G. Tripodi, P. Barassi, C. Camisasca, I. Molinari, M.P. Rastaldi, L. Peters*, P. Ferrari, G. Bianchi (Milan, Italy; *Bar Harbor, USA)

9.30 Identification and intracellular localization of RNA-binding proteins involved in the modulation ofthe hAT1 receptor mRNA stabilityL. Contini, M. Passalacqua, R. Sallo, J.D. Port*, A. Pende, G. Lotti (Genoa, Italy; *Denver, CO, USA)

9.45 Coexistence of different phenotypes in a family with glucocorticoid-remediable aldosteronismF. Fallo*, C. Pilon*, T.A. Williams, N. Sonino*, S. Morra di Cella, F. Veglio, R. DeIasio**, P. Mulatero,(Torino, *Padua and **Bologna, Italy)

10.00 LECTURE:Molecular therapeutic targeting of the metabolic syndrome - A unique effect of a limited subsetof ARBST.W. Kurtz (San Francisco, CA, USA)

Red Hall 2

Sunday, June 15


Blood PressureMeasurement andHaemodynamicsOral Session 4D


ChairmenC. Farsang (Budapest, Hungary)P. Omvik (Bergen, Norway)

8.30 Continuous positive airway pressure therapy has no effect on nocturnal blood pressure inpatients with obstructive sleep apneaR.C. Hermida, C. Zamarron*, D.E. Ayala, M.J. Fontao*, J. Ricoy*, C. Calvo*(Vigo and *Santiago,Spain)

8.45 Clinical prediction of normotension in borderline hypertensive men - A 10 year studyA. Georgiades, U. De Faire, C. Lemne (Stockholm, Sweden)

9.00 Cardiovascular prognosis of “masked hypertension” and of “white coat hypertension”. Resultsof the SHEAF study (Self measurement of blood pressure at Home in the Elderly: Assessmentand Follow-up)G. Chatellier, N. Genes, P. Clerson*, I. Vaur, B. Vaisse**, J.M. Mallion***, G. Bobrie (Paris,*Wattrelos, **Marseille and ***Grenoble, France)

9.15 Is there really cardiovascular abnormality in patients with white coat normotension?O. Ormezzano, J.P. Baguet, P. François, J.L. Quesada, H. Pierre, J.M. Mallion (Grenoble, France)

9.30 A multi-regression model for estimation of central aortic pressure from brachial pressure, heartrate and body sizeA. Avolio, F. Camacho, N. Lovell (Sydney, Australia)

9.45 Diagnostic value of strategy for the detection of white coat hypertension based on ambulatoryand home blood pressure monitoringG. Stergiou, C. Alamara, I. Skeva, T. Mountokalakis (Athens, Greece)

10.00 Clinic pressures underestimate daytime ambulatory blood pressure (DABP) in the young andoverestimate DAPB in middle-aged subjects. The allied Irish bank studyA. Stanton, M. Stojanovic, S. Lyons, N. Atkins, J. Staessen*, E. O’Brien (Dublin, Ireland; *Leuven,Belgium)

10.15 Increased reflective arterial stiffness after stimulation of sympathetic nerve activityA. Scholze, W. Zidek, M. Tepel (Berlin, Germany)

Yellow Hall

Sunday, June 15


PharmacologicalTreatmentOral Session 5A


ChairmenD.E. Grobbee (Utrecht, The Netherlands)J. Staessen (Leuven, Belgium)

11.00 The impact of serum uric acid on cardiovascular outcomes in the LIFE studyA. Hoieggen, M. Alderman*, S.E. Kjeldsen, S. Julius**, R.B. Devereux*, C. Chen***, B. Dahlof° (Oslo, Norway; *New York, NY, **Ann Arbor, MI and ***Withehouse Station, NJ, USA;°Göteborg, Sweden)

11.15 Determinants of progression to microalbuminuria in essential hypertension. A follow-up studyJ.M. Pascual, A. Albert, L. Garcia, R. Julve, A. Gomez, C. Merino, M. Arago, E. Rodilla, C. Gonzalez,J. Redon* (Sagunto and *Valencia, Spain)

11.30 Hypertensive patients at very high risk are not adequately treatedH.P. Stokke, A. Dyrdal, H. Fagertun, I. Os (Oslo, Norway)

11.45 Antihypertensive therapy optimization and impact on quality of life. Minichal StudyA. Roca-Cusachs, X. Badia, A. Dalfó, G. Gascón*, J. Abellán**, R. Lahoz, C. Varela***, O. Velasco*** (Barcelona, *Villarreal, **Murcia and ***Madrid, Spain)

12.00 Reduction of albuminuria in hypertensive type 2 diabetic patients with perindopril/indapamide:the Premier studyC.E. Mogensen, G. Viberti*, S. Halimi** (Aarhus, Denmark; *London, UK; **Grenoble, France)

12.15 Efficacy of treatment of hypertension: a meta-analysis of 68.000 patients and its implications forcurrent practiceA. Azar, A. Hoes, L. Arends*, K. Van den Voorde-Rosenbrand*, M. Bots, B. van Hout, J. Lubsen**,D. Grobbee** (Utrecht and *Rotterdam, The Netherlands; **Paris, France)

Yellow Hall

Sunday, June 15


EpidemiologyOral Session 5B


ChairmenR.E. Kolloch (Bielefeld, Germany)M. Luque-Otero (Madrid, Spain)

11.00 Birthweight does not independently predict blood pressure in 8 year-old Australians: a prospective studyL.J. Beilin, V. Burke, K.V. Blake, D. Doherty, J.P. Newnham, L.I. Landau, F.J. Stanley (Perth, Australia)

11.15 Should pulse pressure become part of the Framingham risk scoreT. Nawrot, J.A. Staessen, L. Thijs, R.H. Fagard, V. Tikhonoff*, J. Wang, S.S. Franklin** (Leuven, Belgium; *Padua, Italy; **Los Angeles, CA, USA)

11.30 Sodium and potassium intake and risk of cardiovascular events and all-cause mortality: the Rotterdam studyD.E. Grobbee, J.M. Geleijnse, J.C.M. Witteman (Utrecht and Wageningen, The Netherlands)

11.45 Microalbuminuria and cardiovascular risk profile in the early stage of hypertension. An insightfrom the HARVEST studyP. Palatini, P. Mormino, M. Santonastaso, L. Mos, M. Dal Follo, T. Biasion, G. Graniero, A. Mazzer, F. Pegoraro, A.C. Pessina (Padua, Italy)

12.00 LECTURE:Birth weight contribution to blood pressure phenotypes in adolescentsE. Lurbe (Valencia, Spain)

Red Hall 1

Sunday, June 15


Diabetes and ObesityOral Session 5C


ChairmenP. Nilsson (Malmö, Sweden)A.M. Sharma (Hamilton, Canada)

11.00 Selective resistance to central administration of leptin in diet-induced obese miceK. Rahmouni, D.A. Morgan, G.M. Morgan, A.L. Mark, W.G. Haynes (Iowa City, IA, USA)

11.15 ANP treatment inhibits cell proliferation and natriuretic peptides receptors gene expression ofcultured adipocytesE. Espinosa, P.F. Marcucci, C. Valentini, M.C. Melatini, A. Micheli, R. Sarzani, A. Rappelli, P. Dessì-Fulgheri (Ancona, Italy)

11.30 Relations between insulin sensitivity, R-R interval, and autonomic cardiovascular regulation inyoung subjects with high and normal screening blood pressureH.M. Reims, K. Sevre, E. Fossum, A. Høieggen, S.E. Kjeldsen (Oslo, Norway)

11.45 A positive family history of hypertension and sympathetic overactivity are predictors ofsubsequent weight gain and blood pressure riseK. Masuo, H. Kawaguchi, H. Mikami, T. Ogihara, M. Tuck* (Osaka, Japan; *Sepulveda, CA, USA)

12.00 Sympathetic overactivity characterizes human obesity independently on the presence ofobstructive sleep apneaG. Grassi, A. Facchini, F. Quarti, R. Dell’Oro, F. Tana, S. Grimaldi, G. Bolla*, M. Robuschi, S. Bianco,G. Mancia (Monza and *Milan, Italy)

12.15 Cardiovascular risk factors of high-normal blood pressure in a Czech population random sampleR. Cifkova, Z. Skodova, V. Lanska, V. Adamkova, E. Novozamska, M. Jozifova, M. Plaskova,D. Palous, M. Galovcova, H. Pistulkova (Prague, Czech Republic)

Red Hall 2

Sunday, June 15



11.00-12.30 Topical Workshop

Dyslipidemia and hypertension

Chairmen:J.P. Bassand (Besançon, France)J.L. Rodicio (Madrid, Spain)

Epidemiological aspectsP. Sleight (Oxford, UK)

Calculation of cardiovascular riskI. Graham (Dublin, Ireland)

Effect of endothelial function and other subclinical organ damageT. Lüscher (Zurich, Switwerland)

TreatmentS.E. Kjeldsen (Oslo, Norway)

Blue Hall

Sunday, June 15



12.30-14.00 Teaching Seminar - Session 2

Chairmen:S. Erdine (Istanbul, Turkey)P.A. van Zwieten (Amsterdam, The Netherlands)

How to diagnose hyperaldosternismA.M. Heagerty (Manchester, UK)

Hypertension in the femalesR. Cifkova (Prague, Czech Republic)

Is there still a place for the ECG in screening hypertensive patients?D. Duprez (Minneapolis, MN, USA)

Clinical case discussion

12.45-13.45 How to assess an echocardiogramC. Cuspidi (Milan, Italy)

Red Hall 2

Sunday, June 15

Blue Hall

Sunday, June 15


Blood PressureMeasurements andHaemodynamicsPoster Session 11


1. Seasonal variations in blood pressureY. Barkai, E. Peleg, T. Rosenthal (Ramat Gan, Israel)

2. Comparison of the seasonal variation of plasma fibrinogen between dipper and non-dipperhypertensive patientsR.C. Hermida, C. Calvo*, D.E. Ayala, J.E. Lopez*, M.J. Dominguez*, M. Covelo*, M.J. Fontao*, R. Soler*, A. Mojon, J.R. Fernandez (Vigo and *Santiago, Spain)

3. Gender differences in the seasonal variation of plasma fibrinogen in patients with essentialhypertensionC. Calvo*, R.C. Hermida, D.E. Ayala, J.E. Lopez*, M.J. Dominguez*, M. Covelo*, M.J. Fontao*, R. Soler*, A. Mojon, J.R. Fernandez (Vigo and *Santiago, Spain)

4. Isolated clinic hypertension is a predictor of cardiovascular risk in womenV. Kotsis, S. Stabouli, E. Manios, V. Pitiriga, R. Zakopoulou, L. Soubassi, J. Lekakis, C. Papamichael,M. Mavrikakis, N. Zakopoulos (Athens, Greece)

5. Predictable variation along gestation of the double (rate-pressure) product in normotensive andhypertensive pregnant womenD.E. Ayala, R.C. Hermida, A. Mojon, J.R. Fernandez, I. Alonso, M.F. Aguilar*, J. Codesido*, M. Iglesias*(Vigo and *Santiago, Spain)

6. 24h ambulatory blood pressure monitoring during pregnancy: methodological aspectsF. Glavina, G. Bilo, D. Manfellotto, G. Covi, D. Rizzoni, N. Lazzarin, A. Tranquilli, C. Borghi, V. Costa,G. Parati (Milan, Italy)

7. Indications of increased susceptibility to hypovolemic circulatory stress in females than in malesM. Lindenberger, H. Olsen*, T. Länne (Linköping and *Helsingborg, Sweden)

8. The estrogen-induced favorable alterations in large artery stiffness are independent on thedipping/non-dipping status in hypertensive postmenopausal womenC. Tsioufis, K. Tzioumis, D. Antoniadis, E. Vezali, L. Naoumidou, A. Hatziyianni, C. Pitsavos, I. Kallikazaros, C. Stefanadis, P. Toutouzas (Athens, Greece)

9. Sampling requirements for the tolerance-hyperbaric test in the diagnosis of hypertension inpregnancyD.E. Ayala, R.C. Hermida, A. Mojon, J.R. Fernandez, I. Alonso, M.F. Aguilar*, J. Codesido, M. Iglesias* (Vigo and *Santiago, Spain)

10. Tolerance intervals for ambulatorily monitored blood pressure in the diagnosis of hypertensionR.C. Hermida, J.R. Fernandez, D.E. Ayala, A. Mojon, I. Alonso, C. Calvo*, M.J. Dominguez*, M. Covelo*, J.E. Lopez* (Vigo and *Santiago, Spain)

12.30-15.30

Sunday, June 15



11. Differences in the slope of morning blood pressure surge between normotensive andhypertensive pregnant womenD.E. Ayala, R.C. Hermida, A. Mojon, J.R. Fernendez, I. Alonso, M.F. Aguilar*, J. Codesido*, M. Iglesias* (Vigo and *Santiago, Spain)

12. Characteristics of circadian rhythm of blood pressure in primary and secondary hypertension inchildrenV. Petrova (Sofia, Bulgaria)

13. Blood pressure and heart rate in students undergoing medical licensing examinationA. Zeller, D. Handschin, E. Battegay, B. Martina (Basel, Switzerland)

14. Variability in daytime ambulatory pulse pressure is dependent on genderA. Stenehjem, V. Bulatov*, I. Os (Oslo, Norway; *Moscow, Russia)

15. Relationship between physical activity and blood pressure in elderly peopleY. Ohta, M. Arita, S. Takeda, I. Nishio (Wakayama, Japan)

16. Blood pressure and haemathological measures of viscosity in Ashanti, West AfricaF.P. Cappuccio, L. Emmett, F.B. Micah*, S.M. Kerry, J. Plange-Rhule*, J.B. Eastwood (London, UK;*Kumasi, Ghana)

17. Acute change in hemodynamics and arterial stiffness after cigarette smoking in black and whitesubjectsD. Lemogoum, M. Leeman, L. Van Bortel*, J.P. Degaute, P. Van de Borne (Brussels and *Ghent,Belgium)

18. Impact of hygienic-dietary intervention in blood pressure control of patients with mildhypertensionR.C. Hermida, D.E. Ayala, C. Calvo*, J.E. Lopez*, M.J. Dominguez*, M. Covelo*, M.J. Fontao*,R. Soler*, A. Mojon, J.R. Fernandez (Vigo and *Santiago, Spain)

19. Differences in pulse pressure between normotensive and white coat hypertensive subjectsC. Calvo*, R.C. Hermida, D.E. Ayala, M. Covelo*, M.J. Dominguez*, A. Mojon, J.R. Fernandez, J.E. Lopez* (Vigo and *Santiago, Spain)

20. Pulse pressure in a sample of hypertensives in an occupational setting in the community ofValencia, SpainF. Fornés, J.L. LListerri*, J.V. Lozano (Valencia and *Alaquas, Spain)

21. Functional indices of pulse pressure are associated to vascular damage in young very mildhypertensives with hyperkinetic syndromeP. Nazzaro, V. Vulpis, T.M. Seccia, G. Schirosi, V. Calabrese, R. Ardito, A.M. Pirrelli (Bari, Italy)

22. Association between pulse pressure diurnal pattern and left ventricular mass index inhypertensive patients with left ventricular hypertrophyL. Kotovskaia, Z.D. Kobalava, I.V. Tsupko, V.S. Moiseev (Moscow, Russia)

23. Systolic and diastolic BP throughout 24h correlate stronger than pulse pressure and heart rate inuntreated mild moderate hypertensivesM. Crippa, S. Ettori, R. Costa, G. Zanolini, N. Colombini, G. Moschini, G. Damiani, R. Fariello(Brescia, Italy)



24. Individual changes of pulse interval variability and blood pressure variability during exerciseN. Honzikova, E. Zavodna, Z. Novakova, A. Krticka (Brno, Czech Republic)

25. Pulsatile and steady 24-h blood pressure components as determinants of left ventricular mass inyoung and middle-aged essential hypertensivesG. Mule’, E. Nardi, V. Volpe, G. Piazza, G. Andronico, S. Cottone, D. Ferrara, G. Cerasola (Palermo,Italy)

26. Relationship between left ventricular mass index and psychological state in hypertensive patientsG. Andreeva, V. Gorbunov, O. Lerman, V. Voronina, O. Isaikina (Moscow, Russia)

27. Left ventricular diastolic function, immunoreactive insulin in essential hypertension patientsdepending on circadian blood pressure rhythmO. Matova, E. Svyshchenko, O. Chervonopiskaya, L. Mishchenko (Kiev, Ukraine)

28. Associations of cardiovascular hemodynamics diurnal changes with blunted blood pressure nightfallM. Mily, S. Golubev, J. Tsai* (Vitebsk, Belarus; *San Diego, CA, USA)

29. Ambulatory blood pressure and cardiovascular riskE. Vinyoles, M. de la Figuera, R. Badia, M. Arcas, E. Escolà, P. Lladonet (Sant Adrià de Besòs, Spain)

30. The pathophysiology of silent myocardial ischaemia in hypertension and coronary arterydisease: supply or demand related?D. Boon, J. van Goudoever, M. Bax, J.J. Piek, G.A. van Montfrans (Amsterdam, The Netherlands)

31. Comparative relevance of ambulatory blood pressure parameters in clinical practiceV. Gorbunov, A. Deev (Moscow, Russia)

32. Eprosartan vs cilazapril once daily monotherapy in mild to moderate hypertensionS. Antonopoulos, P. Megaloikonomos, M. Milonopoulou, F. Stasini, Gr. Giannoulis (Tzancio, Greece)

33. Antihypertensive treatment is unnecesary in one third of patients sent to a hypertension unit.Advantages of patients classification after ambulatory blood pressureP. Cia, A. Martinez-Berganza, I. Yuste, A. Marin, J. Mozota, M. Laclaustra, I. de-los-Martires, P. Cia-Gomez (Zaragoza, Spain)

34. The effect of indapamide on morning blood presure surge and immuno-reactive insulin inessential hypertension patientsV. Radchenko, E. Svyshchenko, L. Mishchenko (Kyiv, Ukraine)


HeartPoster Session 12


35. Is morning surge or nocturnal fall of blood pressure associated with the severity of coronaryheart disease?V. Kotsis, E. Manios, S. Pitiriga, S. Stabouli, I. Ikonomidis, S. Rokas, S. Toumanidis, S. Stamatelopoulos, S. Moulopoulos, N. Zakopoulos (Athens, Greece)

36. Hypercholesterolemia and coronary flow reserve in hypertensive patients without recognizedcoronary heart diseaseM. Galderisi, G. de Simone, S. Cicala, A. D’Errico, O. de Divitiis (Naples, Italy)

37. Prognostic value of exercise stress test and Tc-99m-MIBI heart perfusion study in patients withsyndrome X and hypertensive patients with microvascular anginaM. Popiel, A. Baszko, K. Blaszyk, P. Breborowicz, A. Cieslinski, A. Szyszka, S. Grajek, S. Paradowski(Poznan, Poland)

38. Progression of heart failure during acute myocardial infarction is worse in hypertensives thannormotensivesG. Berton, R. Palmieri*, R. Cordiano*, S. Petucco**, G.L. Guarnieri, E. Brocco, P. Mormino***, P. Palatini*** (Conegliano, *Adria, **Bassano and ***Padua, Italy)

39. Coronary flow reserve and inappropriate left ventricular massM. Galderisi, G. de Simone, S. Cicala, L. De Simone, A. D’Errico, P. Caso, O. de Divitiis (Naples, Italy)

40. The role of adequate blood pressure control on long term prognosis after successful coronarystentingM.N. Zairis, A.J. Manolis, A.G. Lyras, P. Psarogianni, P.C. Batika, S.G. Foussas (Piraeus, Greece)

41. Strain on ECG in hypertensive patients and acute coronary syndromes. Is there any correlation?A. Dermitzakis, E. Kimioni, A. Zaharaki, G. Georgas, A. Apostolaki, E. Manousakis, E. Lambrogianakis, P. Koutsodimou, K. Meidanis, G. Nikolaidis (Heraclion, Greece)

42. Dobutamine increases responses to hypoxia in normal humans and in heart failure patientsS. Velez-Roa, B. Kojonazarov, A. Ciarka, P. Godart, R. Naeije, V.K. Somers*, P. van de Borne(Bruxelles, Belgium; *Rochester, MN, USA)

43. Relative risk of hypertension in coronary heart disease and acute myocardial infarctiondevelopment in elderly population in SpainB. Novella, C. Suarez, R. Gabriel, M. Alonso, S. Vega*, F. Bermejo (Madrid and *Avila, Spain)

44. Study of the role of lipoprotein, as a primary risk factor in patients with myocardial infarctionand arterial hypertensionO.V. Polyakova, G.G. Arabidze, A.I. Ipatov, K.A. Memetov (Moscow, Russia)

45. Quantification of regional myocardial function improved detection of myocardial ischemia inhypertensive patientsM. Deljanin Ilic, S. Ilic, B. Lovic, V. Stoickov (Niska Banja, Yugoslavia)

12.30-15.30

Sunday, June 15



46. Cardiac sympathetic nervous system activity in hypertensive left ventricular hypertrophyN. Zvartau, V. Katcev, O. Mamontov, A. Konrady, V. Amosov (Saint-Petersburg, Russia)

47. Diastolic dysfunction and blood pressure variability in familial arterial hypertensionB.A. Namakanov (Moscow, Russia)

48. Reduced nocturnal fall in blood pressure, assessed by two ambulatory blood pressuremonitorings, and cardiac alterations in early phases of untreated essential hypertensionV. Fusi, C. Cuspidi, I. Michev, S. Meani, B. Severgnini, C. Corti, M. Salerno, C. Valerio, F. Magrini, A. Zanchetti (Milan, Italy)

49. Inflammatory response at onset of acute coronary syndromes in hypertensivesH. Antonakoudis, N. Raikos, G. Vyssoulis, G. Antonakoudis, K. Kifnidis, H. Zisimopulos, V. Papadakis, S. Christacos (Ilioupolis, Greece)

50. ACE inhibitor therapy in hypertensive patients prior to acute myocardial infarction may reducesubsequent morbidity and mortalityS. Ilic, M. Deljanin Ilic, A. Nikolic, V. Mitic, B. Ilic, D. Petrovic (Niska Banja, Yugoslavia)

51. Long-term hypertension and type 2 diabetes mellitus: key factors leading to progression ofcoronary atherosclerosisS.H. Chan, L.M. Tsai, L.J. Lin, J.H. Chen (Tainan, Taiwan)

52. Cardiac morphology and insulin in hypertensive patientsG.P. Carnevale Schianca, R. Rapetti, L. Castello (Novara, Italy)

53. Circulating hepatocyte growth factor in hemodialysis patients is correlated with left ventriculargeometryL.S. Malatino, A. Cataliotti, F.A. Benedetto, B. Stancanelli, I. Bellanuova, P. Belluardo, L. Bonaiuto, G. Tripepi, F. Mallamaci, C. Zoccali (Catania and *Reggio Calabria, Italy)

54. Ultrasound tissue characterization in patients with chronic renal failureM. Salvetti, M.L. Muiesan, C. Monteduro, A. Paini, B. Bonzi, P. Poisa, G. Cancarini, E. Agabiti-Rosei(Brescia, Italy)

55. Impact of microalbuminuria on left ventricular structure and function in hypertensive diabeticpatientsM. Picca, F. Agozzino, G.C. Pelosi (Milan, Italy)

56. Do both left ventricular hypertrophy and abnormal glucose metabolism contribute to abnormalleft ventricular filling in patients attending a hypertensive clinic?A.M. Salmasi, E. Jepson, M. Dancy (London, UK)

57. Cellular hypoxia due to hypertension - A possible cause of myocardial damage in chronic renalfailure patients undergoing hemodialysis treatmentM. Wanic, M. Kobelski, E. Pawliczak, L. Koziol, S. Czekalski (Poznan, Poland)

58. Renal natriuretic peptide system mediates the effects of a highly potent MU opioid receptoragonist (cUENK6)J. Gutkowska, S. Mukaddam-Daher, M. Jankowski, J. Izdebski* (Montreal, Canada; *Warsaw,Poland)



59. Relation between serum uric acid and coronary artery calcification in patients with essentialhypertensionS. Altunkan, N. Erdogan, L. Altin, E. Altunkan (Ankara, Turkey)

60. Serum N-terminal pro brain natriuretic peptide as a marker of cardiac dysfunction in ALamyloidosisS. Perlini, G. Palladini, M. Vezzoli, C. Campana, C. Klersy, A. Balduini, G. Vadacca, V. Perfetti,L. Obici, G. Merlini (Pavia, Italy)

61. Elevation of aldosterone drives persistent cardiac fibrosis independent of blood pressure controlD.G. MacKenzie, N.G. McDicken, D.J. Webb, M.A. Denvir (Edinburgh, UK)

62. Prevalence of left ventricular remodelling, intima-media thickening and endothelial dysfunction in untreated hypertensive patients: the St. Petersburg studyA. Konrady, O. Rudomanov, N. Vahromeeva, O. Iakovleva, T. Vinnic, Y. Kasherininov, E. Lyasnicova,E. Shavarova, E. Shlyakhto (Saint-Petersburg, Russia)

63. Effect of protein kinase C isoforms on collagen gel contraction and collagen production incardiac fibroblastP. Lijnen, V. Petrov, R. Fagard (Leuven, Belgium)

64. Left ventricular structure and endothelial function in non-treated mild-to-moderate essentialhypertensive patientsP. Strozecki, M. Kretowicz, M. Ukleja-Adamowicz, G. Odrowaz-Sypniewska, J. Manitius (Bydgoszcz, Poland)

65. Hypertrophied myocardium is more sensitive to oxydative stressE. Kalenikova, E. Gorodetskaya, A. Murashev*, E. Ruuge, O. Medvedev (Moscow and *Pushchino,Russia)


Vasoactive Substancesand NeurohormonesPoster Session 13


66. Prevalence of primary aldosteronism among hypertensive patientsR. Fogari, P. Preti, A. Mugellini, A. Rinaldi, C. Pasotti, E. Fogari, L. Corradi (Pavia, Italy)

67. Epinephrine response to glucagon characterizes pheochromocytoma cells and not normalchromaffin cells: study of primary bovine adrenomedullary cellsY. Sharabi, R Zimlichman*, T. Huynh, R. Mansouri, J. Chun, G. Eisenhofer, S. Alesci, K. Pacak, D.S. Goldstein (Bethesda, USA; *Holon, Israel)

68. Improved visualization of adrenal masses with compound or three-dimensional ultrasound andtissue harmonic imagingR.Z. Slapa, T.K. Dobrucki, A.A. Kasperlik-Zaluska, M. Peczkowska, A.M. Pajk, A. Prejbisz, I. Cybulska, M. Kabat, W. Jakubowski, A. Januszewicz (Warsaw, Poland)

69. A scoring system increases specificity of I-MIBG scan for the diagnosis of pheochromocytomaM.C. Marzola, D. Cecchin, P. Zucchetta, S. Morando, P. Faggin, C. Scaroni, F. Lumachi, G. Opocher,F. Mantero, F. Bui (Padua, Italy)

70. Clinical significance of serum CMA level for the screening of pheochromocytoma in hypertensivesC. Mounier Vehier, F. Biausque, O. Jaboureck, P. Hainaut, P. Devos, M. D’Herbomez, A. Carré (Lille, France)

71. Plasma adrenomedullin level in patients with essential hypertension, primary aldosteronism andpheochromocytomaM. Makowiecka-Ciesla, A. Wiecek*, A. Januszewicz, A. Prejbisz, M. Kabat, J. Janas, M. Januszewicz,W. Ciesla, W. Szaroszyk, P. Hoffman (Warsaw and *Katowice, Poland)

72. Role of nitric oxide in hypotensive, cardiac and renal actions of atrial natriuretic peptideM.A. Costa, R. Elesgaray, A. Loria, R. Marianeschi, A. Betz, M.C. Arias, A.M. Balaszczuk, C. Arranz(Buenos Aires, Argentina)

73. Salt, endogenous ouabain and blood pressure interactions in the general populationJ.G. Wang, J.A. Staessen, E. Messaggio*, T. Nawrot, R. Fagard, J.M. Hamlyn**, G. Bianchi*,P. Manunta* (Leuven, Belgium; *Milan, Italy; **Baltimore, USA)

74. Plasma cardiotrophin-1, a biomarker of myocardial stress in hypertensive heart disease?A. González, B. López, M. Sánchez del Pino, A. Díaz, M.A. Fortuño, M. Serrano**, J. Barba, R. Querejeta*, J. Díez (Pamplona and *San Sebastián, Spain)

75. Plasma adrenomedullin concentrations in patients with essential, renovascular and malignanthypertensionC. Letizia, C. Caliumi, M. Celi, R. Cianci, G. De Toma, S. Cerci, D. Cotesta, L. Petramala, M. Iorio, V. Serra (Rome, Italy)

76. A clinical prediction rule for primary aldosteronism in drug-resistant hypertensive patientsreferred to an hypertension clinicX. Girerd, F. Villeveuve, A. Lemaire, O. Roux, O. Hanon, J.J. Mourad (Paris, France)

12.30-15.30

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77. Diadenosine heptaphosphate: a new potent vasoconstrictive substance of human plateletsJ. Jankowski, M. Giet, H. Schluter, W. Zidek (Berlin, Germany)

78. Aldosterone to PRA ratio in the diagnosis of primary aldosteronismG.P. Bernini, A. Moretti, S. Favilla, P. Duranti, A. Salvetti (Pisa, Italy)

79. No association between IGF-1 and LV-mass in hypertensive patientsV. Pitiriga, E. Karga, V. Kotsis, N. Kokolakis, V. Gennimata, N. Zakopoulos (Athens, Greece)

80. Markers of endothelial dysfunction in severe hypertension of primary and secondary originJ. Widimsky jr, D. Zogala, J. Kvasnicka, J. Skrha (Prague, Czech Republic)

81. Bone metabolic parameters and AMBP-24h in patients with primary hyperparathyroidismC. Letizia, M. Celi, C. Caliumi, S. Cerci, D. Cotesta, A. Schiappoli, V. Serra, L. Petramala, E. D’Erasmo, G.F. Mazzuoli (Rome, Italy)

82. Diurnal profile of plasma leptin, noradrenalin and adrenalin concentrations in patients withessential hypertension and obstructive sleep apnea syndromeB. Wocial, M. Raczkowska, H. Berent, K. Kuczynska, J. Lewandowski, B. Symonides, P. Gryglas, A. Kazmierczak, M. Lapinski (Warsaw, Poland)

83. Leptin does not mediate impaired aortic compliance in obese hypertensive patientsT. Kosicka, A. Rutz-Danielczak, B. Krasinska, A. Tykarski, J. Gluszek (Poznan, Poland)

84. Diurnal profile of plasma leptin concentration in dipper and non-dipper essential hypertensivesM. Raczkowska, K. Kuczynska, H. Berent, B. Wocial, J. Lewandowski, P. Gryglas, B. Symonides, H. Switalska, M. Lapinski (Warsaw, Poland)

85. Hyperinsulinemia and pulse pressure in elderly hypertensive patientsA. Garcia Noain, A. Muñoz Mellado, R. Boldova Aguar, A. Martinez-Berganza Asensio, P. Cia Gomez(Zaragoza, Spain)

86. High-normal and impaired fasting plasma glucose are associated to early organ damage inhypertensive patientsC. Campo, J. Segura, C. Roldán, L. Vigil, L. Guerrero, L. Fernández, M.C. Casal, J.L. Rodicio, R.Gª Robles, L.M. Ruilope (Madrid, Spain)

87. Intermediate endpoints and the response of serum glucose to an OGGTC. Campo, J. Segura, C. Roldán, L. Vigil, M.C. Casal, L. Fernández, L. Guerrero, J.L. Rodicio, R.Gª Robles, L.M. Ruilope (Madrid, Spain)

88. Cardiovascular variability in patients with hypothyroidism post thyroidectomy and during thyroidhormone treatmentL. Guasti, E. Piantanida, C. Simoni, L.T. Mainardi*, P. Vanoli, D. De Palma, C. Crespi, F. Marino, M. Cosentino, G. Gaudio (Varese and *Milan, Italy)

89. Sexual activity and testosterone plasma levels in hypertensive patients treated with an AT1angiotensin II receptor antagonist or a cardioselective beta-blockerH. Grassos, D. Kontogianni, N. Kouris, E. Kalkandi, M. Sifaki, G. Goranitou, D. Babalis (Athens, Greece)

90. Prevalence of primary hyperaldosteronism in moderate to severe hypertension in Central EuroperegionB. Strauch, T. Zelinka, M. Hampf*, R. Bernhardt ** (Prague, Czech Republic; *Saarbruecken and**Berlin, Germany)



91. Oxygen free radicals and left ventricular hypertrophy in essential hypertensionM. Mettimano, M.L. Specchia, C. Calla, S. Lippa, M. Colacicco, A. Bruno, L. Savi (Rome, Italy)

92. Diurnal blood pressure variation in different types of endocrine hypertension and the effect ofspecific treatmentT. Zelinka, J. Widimsky, B. Strauch (Prague, Czech Republic)

93. Proof of rapid vascular aldosterone effectsB.M.W. Schmidt, S. Oehmer, C. Delles, M.P. Schneider, E.H. Fleischmann, R.E. Schmieder(Nuremberg, Germany)

94. Selected biomarkers of oxidative stress in patients with essential hypertensionA. Goch, P. Fijalkowski, P. Galecki, J. Blaszczyk, J.H. Goch (Lodz, Poland)

95. Effect of gonadectomy on cardiovascular activity in normal and stressed male and female ratsM. Semyonova, T. Anishchenko, L. Simakina (Saratov, Russia)

96. Vasoactive intestinal peptide in essential hypertensionC. Letizia, P. Lucia, L.L. Manetti, S. Caiola, S. Subioli, C. Cianfrocca, E. D’Erasmo, C. De Martinis(Rome, Italy)


Blood VesselsPoster Session 14


97. Genetics of susceptibility to aortic lesions and aneurysms in Brown Norway and Brown NorwayKatholiek rat strainsE. Kaschina, M. Stoll*, R. Kreutz, T. Unger (Berlin and *Kiel, Germany)

98. Genetic variation in matrix metalloproteinases contributes to large artery stiffening througheffects on gene and protein expressionT. Medley, T. Cole, A. Dart, B. Kingwell (Melbourne, Australia)

99. Plasma adiponectin concentration in hypertensive patients with coronary artery disease with orwithout carotid and/or renal artery stenosisA. Januszewicz, Z. Dzielinska, A. Wiecek*, A. Prejbisz, T. Zielinski, M. Makowiecka-Ciesla, M. Demkow, J. Kadziela, M. Januszewicz, W. Ruzyllo (Warsaw and *Katowice, Poland)

100. Alfa1-antitrypsin deficiency and blood pressure regulationÅ. Rydén Ahlgren, E. Piitulainen*, T. Sandgren*, T. Länne** (Malmö, *Helsingborg and **Linköping,Sweden)

101. Influence of isoproterenol on augmentation indexD. Lemogoum, W. Van den Abeele*, A. Ciarka**, L. Van Bortel, M. Leeman, J.P. Degaute, P. Van de Borne (Brussels and *Ghent, Belgium; **Warsaw, Poland)

102. Influence of calcineurin-inhibitor free immunosuppression on carotid intima media thickness inchronic allograft nephropathyB. Suwelack, U. Gerhardt, H. Hohage (Münster, Germany)

103. In vivo effects of fluvastatin on leukocyte vascular trafficking under experimental acuteinflammatory conditionsF. Fischetti, B. Fabris, M. Bardelli, R. Candido, F. Fior, L. Macaluso, M. Bossi, R. Gerloni, D. Belgrado,R. Carretta (Trieste, Italy)

104. Differential effects of combined and uncombined replacement therapy on large artery elasticityin hypertensive postmenopausal womenK. Tzioumis, C. Tsioufis, P. Zambaras, D. Antoniadis, T. Psarros, S. Lalos, C. Pitsavos, I. Kallikazaros,C. Stefanadis, P. Toutouzas (Athens, Greece)

105. Impaired arterial compliance is more common in hypertensive women than menD. Longo, G. Toffanin, R. Garbelotto, C. Sanigi, P. Frezza, S. Zaetta, R. Businaro, L. Mos*, A.C. Pessina, P. Palatini (Padua and *S. Daniele del Friuli, Italy)

106. Vascular phenotype in patients with Ehlers-Danlos syndrome, vascular type: rationale for theBBEST study: beta blockers in Ehlers-Danlos syndrome, vascular typeP. Boutouyrie, D.P. Germain, M. Lemerrer, P. Collignon*, J. Perdu, J.N. Fiessinger, E. Koenig-Berard,J. Schachmann, S. Laurent (Paris and *Toulon, France)

12.30-15.30

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107. Remodelling of vascular connective tissue by enalapril, valsartan, felodipine and fluvastatin ingenetically hypertensive ratsY. Millard, J. Ledingham, I. Appleton, R. Laverty (Dunedin, New Zealand)

108. Candesartan cilexetil and atenolol have different effects on common carotid artery remodellingin hypertensionB. Ariff, A. O’Neill, A. Stanton*, A. Zambanini, S. Vamadeva, N. Poulter, P. Sever, Y. Xu, A. Hughes, S. Thom (London, UK; *Dublin, Ireland)

109. Effect of fluvastatin on migration in vascular smooth muscle cells from spontaneouslyhypertensive ratsL. Xie, Y. Han, C. Xu, H. Wang (Fuzhou, China)

110. Comparative effects of perindopril-indapamide and losartan on arterial smooth musclerelaxationL. Brandani, S. Graf, R. Armentano, A. Ramirez, R. Sanchez, H. Baglivo (Buenos Aires, Argentina)

111. Aldosterone antagonism reduces arterial stiffness in hypertensionA. Mahmud, J. Feely (Dublin, Ireland)

112. Nebivolol reduces large artery stiffness in vivoC. McEniery, M. Schmitt*, A. Qasem**, A.P. Avolio**, D.J. Webb***, J.R. Cockcroft*, I.B. Wilkinson(Cambridge, *Cardiff and ***Edinburgh, UK; **Sydney, Australia)

113. Ovarian hormones attenuate vascular structural changes in DOCA-salt ratsA.C.M. Montezano, A.L. Mota, Z.B. Fortes, M.H.C. Carvalho, D. Nigro, T.M.T. Zorn, R.C. Tostes (São Paulo, Brazil)

114. Disparate effects of vitamin C and N-acetylcysteine on vascular dysfunction in subjects withessential hypertensionM.P. Schneider, S. John, S. Oehmer, B.M.W. Schmidt, A.U. Klingbeil, R.E. Schmieder (Nürnberg, Germany)

115. Does allopurinol prevent side effects of cyclosporine A treatment?B. Suwelack, U. Gerhardt, F. Matzkies, V. Kobelt, H. Hohage (Münster, Germany)

116. Influence of angiotensin II type I receptor gene A1166C polymorphism on blood pressure andaortic stiffness among Malay hypertensive subjects; a preliminary reportA. Rehman, A.R.A. Rahman, S.B. Ismail, L. Naing (Kota Bharu, Malaysia)

117. Carotid arterial compliance changes during hormone replacement therapy in hypertensivemenopausal womenM. Bystrova, A. Britov, N. Kalinkina, A. Deev (Moscow, Russia)

118. Irbesartan improves arterial compliance of muscular arteries more than lisinoprilC. Rajkumar, S. Armsrong, C.J. Bulpitt (London, UK)

119. Treatment with amlodipine and atorvastatin have additive effect in improvement of arterialelasticity in hypertensive hyperlipidemic patientsE. Leibovitz, M. Beniashvili, R. Zimlichman, A. Freiman, M. Shargorodsky, D. Gavish (Holon, Israel)



120. Acute effect of tea on arterial stiffnessC. Vlachopoulos, N. Alexopoulos, F. Kosmopoulou, D. Korres, C. Stratos, S. Stamatelopoulos, P. Toutouzas, C. Stefanadis (Athens, Greece)

121. Repeated exposure to caffeine increases arterial stiffnessC. Vlachopoulos, A. Sofianidou, F. Kosmopoulou, N. Alexopoulos, M. O’Rourke*, S. Stamatelopoulos,P. Toutouzas, C. Stefanadis (Athens, Greece; *Sydney, Australia)

122. An evaluation of short and long term effects of smoking and smoking cessation on arterialcompliance by non invasive pulse wave analysisS. Oren, I. Isakov, C. Yosefi, S. Turkot, B. Golzman, Y. Kogan (Ashkelon, Israel)

123. Description and validation of a new method to evaluate retinal microcirculation changesA. Pose-Reino, M. Rodriguez-Fernandez, B. Hayik, F. Gomez-Ulla, L. Lopez-Barreiro, J.M. Martínez-Comendador, F. Gude (Santiago de Compostela, Spain)

124. Comparison of the Complior and Sphygmocor systems for measuring pulse wave velocityS. Millasseau, S. Patel, S. Redwood, P. Chowienczyk (London, UK)

125. 2-dimensional arterial wall movement measurements - Evaluation and first in vivo trial of non-invasive ultrasonic methodM. Persson, Å. Rydén Ahlgren*, T. Jansson, A. Eriksson, H.W. Persson, K. Lindström (Lund andMalmö, Sweden)

126. Hypertension and non traditional risk factors for atherosclerosis in systemic lupus erythematosuspatientsM. Puato, A. Doria, E. Favaretto, L. Pagliani, C. Tirrito, M. Rattazzi, S. Zampieri, R. Wu*, Y. Shoenfeld**, P. Pauletto (Padua, Italy; *Santa Monica, USA; **Tel Aviv, Israel)


EndotheliumPoster Session 15


127. Association between C-reactive protein,fibrinogen and microalbuminuria in essential hypertensionO. Koutsogiannis, V. Karagiozaki, I. Litsas, L. Mporgi, S. Terzi, A. Gotsis, C. Mamoutos, A. Panagiotidou (Komotini, Greece)

128. Greater contribution by hypercholesterolemia than by other cardiovascular risk factors indetermining conduit artery endothelial dysfunctionL. Ghiadoni*, G. Bilo, A. Magagna*, I. Kardasz*, D. Versari*, F. Glavina, S. Taddei*, G. Parati, G. Mancia, A. Salvetti* (Milan and *Pisa, Italy)

129. Carotid artery remodeling and endothelial function in patients with cardiac hypertrophyF. Bartolomucci, G. Barone, N. D’Alitto, M. Kozakova*, C. Palombo*, G. Maiorano (Bari and *Pisa,Italy)

130. Flow mediated dilatation in systemic sclerosis: effects of iloprost treatmentC. Giannattasio, G. Gentile, M. Failla, M. Pozzi, M. Gardinali, E. Meles, C. Zazzeron, E. Fantini, S. Maestroni, G. Mancia* (Monza and *Milan, Italy)

131. The association of endothelial dysfunction with endothelial nitric oxide synthase gene polymorphism in essential hypertension and heart failure: a controlled studyS. Demirel, H. Gençhellaç, N. Çine, H. Oflaz, M. Ala, S. Vatansever, V. Akkaya, O. Erk, M. Dilmener,S. Erdine (Istanbul, Turkey)

132. Marked alterations in fibrinolytic function preexist in healthy offspring of hypertensive patientsT. Makris, A. Hatzizacharias, P. Krespi, D. Papadopoulos, P. Margos, N. Pantazopoulos, M. Kouli, H. Michalopoulou, V. Votteas (Athens, Greece)

133. Are adhesion molecules related to blood pressure? Results from a multiethnic populationM.A. Miller, F.P. Cappuccio (London, UK)

134. White coat hypertension vs. primary hypertension: the predictive role of ambulatory bloodpressure monitoring on the indices of endothelial functionM. Aydinli, S. Kahraman, E. Akpinar, B. Altun, M Arici, S. Kirazli, Y. Erdem, U. Yasavul, Ç. Turgan, S. Çaglar (Ankara, Turkey)

135. Effects of smoking on serum antioxidant and endothelial dysfunction after a high-fat mealW-C. Tsai, C-C. Lin, Y-H. Li, J-H. Chen (Tainan, Taiwan)

136. Effects of chronic smoking on thrombosis/fibrinolysis systemM. Toutouza, K. Vasiliadou, N. Giotsas, C. Antoniades, D. Tousoulis, C. Tsioufis, S. Ntaskas, C. Tentolouris, C. Stefanadis, P. Toutouzas (Athens, Greece)

137. Analysis of endothelial function by means of flow mediated dilation in the normal blood pressurerange. Is there a place for the J-curve controversy in the endothelium?M. Laclaustra, P. Gonzalez-Garcia, J.A. Cuenca, M. Gonzalez-Carretero, J.A. Casasnovas, I.J. Ferreira,P. Cia (Zaragoza, Spain)

12.30-15.30

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138. Swimming improved endothelium-dependent vascular relaxation in patients with essentialhypertensionM. Arita, M. Mizuta, M. Utsumi, T. Sanke, I. Nishio, S. Takeda (Wakayama, Japan)

139. Vasodilatation function in elderly hypertensives with and without diabetes mellitusL. Xie, Y. Yan, P. Li, X. Wu (Fuzhou, China)

140. Endothelium vasomotor function after LDL-apheresis in patients with familialhypercolesterolemiaM. Bardelli, F. Fiammengo, M. Bossi, L. Cattin, M. Malacrea, L. Macaluso, R. Gerloni, B. Fabris, R. Candido, R. Carretta (Trieste, Italy)

141. Influence of acute hyperglycemia on peripheral circulation, sympathetic nervous system and NOproduction in normotensive individualsA. Konrady, E. Berngardt, A. Zgloba (Saint-Petersburg, Russia)

142. Hypertensive non-dippers have worse endothelial function than dippersA. Rapaee, H. Nawawi*, Y. Zulina*, K. Yusoff* (Kuching and *Kuala Lumpur, Malaysia)

143. Endothelial dysfunction in sustained and white coat hypertensionY. Karter, S. Aydyn, A. Çurgunlu, H. Uzun, N. Ertürk, S. Vehid, A. Yaldyran, E. Öztürk, S. Erdine(Istanbul, Turkey)

144. Endothelium-derived vasorelaxing factor and different types of left ventricular geometry inpatients with hypertensionO. Nyzhegorodtseva, O. Kovalyova (Kharkov, Ukraine)

145. High activity of dimethylarginine dimethylaminohidrolase in chronic renal failure patientssubmitted to dialytic treatmentH. Luz Rodrigues, C. Thiran, L. Breitenfeld, F. Neves*, A. Carvalho*, M. Bicho (Lisbon and*Santarém, Portugal)

146. Relation between endothelium dependent relaxation function and endothelin in elderlyhypertensivesL. Xie, Y. Yang, T. Lin, X. Wu (Fuzhou, China)

147. Hyperhomocysteinemia: an additional risk factor in white coat hypertensionY. Karter, H. Uzun, A. Çurgunlu, S. Aydyn, N. Ertürk, S. Vehid, G. _im_ek, E. Öztürk, S. Erdine(Istanbul, Turkey)

148. Plasma neuropeptide Y level in essential hypertensive patientsS. Koval, M. Penkova, R. Pashtiani, T. Starchenko (Kharkov, Ukraine)


Brain and CognitiveFunctionPoster Session 16


149. Cerebral autoregulation assessed by time and frequency domain analysis is impaired in acutestrokeR. Immink, G. van Montfrans, J. Stam, J. Karemaker, M. Diamant, J. van Lieshout (Amsterdam, The Netherlands)

150. Reduced whole brain volumes, increased white matter lesions but normal hippocampal volumein older hypertensive subjectsR.M. Wiseman, E.J. Burton, R. Barber, J.T. O’Brien, G.A. Ford (Newcastle upon Tyne, UK)

151. Is there a side predilection for cerebrovascular disease?S.A. Rodríguez Hernández, A.A. Kroon, M.P.J. van Boxtel, W.H. Mess, J. Lodder, J. Jolles, P.W. de Leeuw (Maastricht, The Netherlands)

152. Potentiation of arterial baroreceptor reflexes by slow controlled breathing in healthy humansA. Radaelli*, R. Raco*, A. Viola*, P. Perfetti*, G. Signorini, A.U. Ferrari (Milan and *Seregno, Italy)

153. Comparative evaluation of cognitive function in elderly patients in primary careL.F. Santos, J.F. Kerr Saraiva, A.M. Cunha Jr., M.F. Santos, A.R.B. Sannazzaro, M.F.M. Scudeler, C.R. Mendes (Campinas, Brazil)

154. Prevalence of arterial hypertension, diabetes and atrial fibrillation in patients with stroke:analysis of 1183 casesS. Voyaki, A. Efstratopoulos, A. Baltas, L. Mourgos, V. Lekakis, S. Siasiakou, A. Hantzis, T. Gialernios, H. Tsougos*, M. Paximadakis* (Athens and *Elefsis, Greece)

155. Cerebral edema in acute stroke patients is associated with increased clinic and ambulatoryblood pressureV. Kotsis, G. Tsivgoulis, A. Synetos, K. Spengos, E. Manios, S. Stabouli, R. Zakopoulou, V. Pitiriga,K. Vemmos, N. Zakopoulos (Athens, Greece)

156. Impaired cerebral vasoreactivity in hypertensives: an early marker of vascular dementia?A. Realdi, V. Mascagna, L. Ciccariello, L. Macchini, V. Benetton, F. Del Piccolo, D. Mapelli, P. Amodio,A. Maresca, A. Semplicini (Padua, Italy)

157. Magnetic resonance imaging of the brain, intra-extra cranial arteries and veins in the patientswith lupus erythematosus N. Abramova, O. Belichenko, I. Klukvina, S. Shekshina, S. Shakhidzhanova (Moscow, Russia)

158. Hypertension and cerebral vascular lesions in patients after heart valve replacementJ. Auer, T. Weber, R. Berent, R. Zisch, G. Lamm, E. Lassnig, B. Eber (Wels, Austria)

159. Cardioinhibitory type responses of carotid sinus stimulation are closely associated with carotidartery stiffness in essential hypertensive subjectsC. Tsioufis, K. Thomopoulos, V. Katsi, P. Zambaras, A. Arapoyianni, K. Toutouzas, I. Kallikazaros, C. Pitsavos, C. Stefanadis, P. Toutouzas (Athens, Greece)

12.30-15.30

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160. Evolution and prognosis of high blood pressure during acute stroke in subjects with lacunarinfarction in comparison with ischemic non lacunar strokesL.M. Ceresuela (L’Hospitalet de Llobregat, Spain)

161. Characteristics of stroke patients with and without history of hypertensionR. Suarez-Otero, E. Oropeza de la Madrid, M. Torres-Rodriguez (Toluca, Mexico)

162. Age is associated with subtypes of acute strokeV. Kotsis, A. Synetos, E. Manios, G. Tsivgoulis, S. Stabouli, V. Pitiriga, R. Zakopoulou, K. Vemmos,M. Mavrikakis, N. Zakopoulos (Athens, Greece)

163. Oxidative stress in intracerebral hematomas appeared as a consequence of hypertensionO. Gore, C. Gore, R. Papacocea, T. Papacocea (Bucharest, Romania)

164. Influence of valsartan and enalapril on cognitive function in elderly hypertensive patientsR. Fogari, A. Mugellini, P. Preti, G.L. Marasi, E. Fogari, A. Rinaldi (Pavia, Italy)

165. Efficacy of nebivolol 24-weeks monotherapy on carbohydrates and lipids metabolism, bloodpressure and brain perfusion in patients with metabolic syndromeV. Gornostaev, V. Mychka, I. Dvoskina, V. Sergienko, V. Buvaltsev, I. Chazova (Moscow, Russia)

166. Contribution of nitric oxide to retinal perfusion is reduced in hypertensive patients but can berestored by treatment with candesartan cilexetilC. Delles, J. Harazny, S. Oehmer, G. Michelson, R.E. Schmieder (Erlangen, Germany)

167. Effect of perindopril and atenolol on plasma PAI-1 in hypertensive patients with acute ischemicstrokeR. Fogari, C. Pasotti, A. Zoppi, L. Corradi, A. Mugellini, P. Preti, E. Malacco*, A. Rinaldi (Pavia and*Milan, Italy)


EpidemiologyPoster Session 17


168. Blood pressure control in hypertensive patients. Preliminary results from a survey in generalpractice: the Insubria studyA.M. Grandi, A. Sessa, R. Stella, A. Maresca, D. Ponti, E. Barlocco, F. Banfi, A. Venco (Varese, Italy)

169. Prevalence of high blood pressure and overweight in children of a suburban area in northernItalyF. Pieruzzi, S. Genovesi, M. Giussani, F. Vigorita, A. Rizzi, C. Dossi, S. Cavuto, A. Stella(Monza, Italy)

170. The prevalence of metabolic syndrome in young adultsA. Soysal, D. Soysal, R. Ucku, M. Koseoglu, C. Cevik, Y. Demiral, G. Aksakoglu (Izmir, Turkey)

171. Is the assessment of kidney involvement in French patients with essential hypertensionsatisfactory? A nationwide survey in general practice (Phenomen)C. Mounier Vehier, G. Amah, S. Duquenoy, P. Fontaine, T.M. Phan (Lille, France)

172. Prevalence of insomnia in the Warsaw metropolitan area (POL-MONICA BIS) - Relationship tohypertension and other cardiovascular risk factorsJ. Piwonski, W. Piotrowski, A. Prejbisz, A.J. Dabrowska, M. Kabat, W. Szelenberger, S. Rywik, A. Januszewicz (Warsaw, Poland)

173. Incidence of hypertension in a French working population: the IHPAF studyS. Radi, T. Lang, V. Lauwers-Cancès, G. Chatellier*, J.P. Fauvel**, L. Larabi***, R. De Gaudemaris*** (Toulouse, *Paris, **Lyon and ***Grenoble, France)

174. An audit of hypertension management in patients hospitalised in internal medicine wards: is it optimal?R. Yilmaz, S. Kahraman, C. Gonen, G. Genctoy, M. Arici, B. Altun, Y. Erdem, U. Yasavul, C. Turgan, S. Caglar (Ankara, Turkey)

175. Residual coronary risk in treated hypertensives: the PRIME studyJ. Blacher, A. Evans, D. Arveiler, P. Amouyel, J. Ferrières, A. Bingham, J. Yarnell, B. Haas, M. Montaye, P. Ducimetière (Villejuif, France)

176. Blood pressure distribution in a Hungarian adolescent population: comparison with normalvalues in the USAD. Páll, É. Katona, B. Fülesdi, M. ZrínyI, J. Zatik, D. Bereczki, P. Polgár, G. Kakuk (Debrecen,Hungary)

177. Primary Care doctor’s attitude in the Spanish hypertensive population. PRESCAP 2002 StudyG.C. Rodríguez-Roca, F.J. Alonso-Moreno, J.V. Lozano-Vidal, J.L. Llisterri-Caro*, J.A. Santos-Rodríguez**, O. García-Vallejo, J.A. Divisón-Garrote***, A. Raber-Béjar°°, R. Pacheco-López°° (Toledo, *Valencia, **La Coruña, ***Albacete, °Madrid and °°Barcelona, Spain)

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178. Characteristics and degree of blood pressure control of the Spanish hypertensive populationconsulted in primary care. PRESCAP 2002 studyJ.L. Llisterri-Caro*, G.C. Rodríguez-Roca, F.J. Alonso-Moreno, J.V. Lozano-Vidal****, J.A. Santos-Rodríguez**, O. García-Vallejo°, J.A. Divisón-Garrote***, A. Raber-Bejar°°, R. de Castellar-Sansó°°(Toledo, *Valencia, **La Coruña, ***Albacete, ****Valencia, °Madrid and °°Barcelona, Spain)

179. Prevalence of metabolic syndrome in the Spanish primary care population with highcardiovascular risk. EVENTO studyG.C. Rodríguez-Roca, J.L. Llisterri-Caro*, F.J. Alonso-Moreno, J.V. Lozano-Vidal°, J. Aznar-Vicente°°°,J.A. Santos-Rodríguez**, J.A. Divisón-Garrote***, O. García-Vallejo°° (Toledo, *Valencia, **La Coruña, ***Albacete, °Valencia, °°Madrid and °°°Alicante, Spain)

180. Degree of main cardiovascular risk factors control in the Spanish primary care high-riskpopulation. EVENTO studyJ.L. Llisterri-Caro*, G.C. Rodríguez-Roca, F.J. Alonso-Moreno, J. Aznar-Vicente°°°, J.V. Lozano-Vidal°, O. García-Vallejo°°, J.A. Divisón-Garrote***, J.A. Santos-Rodríguez** (Toledo, *Valencia,**La Coruña, ***Albacete, °Valencia, °°Madrid, °°°Alicante, Spain)

181. The “FRANCIACORTA” Study: A perspective, cohort, epidemiological study to assess the actualclinical relevance of the potential changes in the management of hypertension induced by theimplementation of the 1999 WHO-ISH guidelinesA. Piccoli, A. Soglian*, S. Calebich, R. Spezia* and the Franciacorta Study Collaborative Group* (Ome and *Milan, Italy)

182. Quality of blood pressure control and arterial hypertension treatment in the large industrialcentre of Ukraine (based on the data of patients’ anonymous questioning) S. Koval, L. Maslyaeva, D. Miloslavskiy, O. Mysnichenko, V. Zinova (Kharkov, Ukraine)

183. World wide Web and patients: profile of the patients connected on to the Web and validation ofmedical surveyP. Laurent, G.V. Dussarat, C. Mounier-Vehier**, Y. Dimitrov***, H. Laurent*, A. Marquand°,X. Girerd* (Toulon, *Paris, **Lille, ***Strasbourg and °Fréjus, France)

184. Evaluation of the knowledge and management of high blood pressure in an hypertensivepopulation: an Internet evaluation studyP. Laurent, H. Laurent*, G.V. Dussarat, X. Girerd* (Toulon and *Paris, France)

185. Estimates of losartan-induced versus atenolol-induced reduction of strokes in patients witharterial hypertension and electrocardiographic left ventricular hypertrophy in GermanyK. Krobot, W. Gerth*, H.C. Diener° (Haar and °Essen, Germany; *USA)

186. Cardiovascular risk factors in 17-18 year old adolescents in PolandL. Plaszewska-Zywko, E. Kawalec (Cracow, Poland)

187. Ambulatory pulse pressure in a rural hypertensive population of primary careG.C. Rodríguez-Roca, F.J. Alonso-Moreno, A. García-Jiménez, B. Adán-Ledrado**, Y. Delgado-Cejudo, J.L. Llisterri-Caro* (Toledo and *Valencia, Spain)

188. Spectral analysis of 50-year record of mortality from stroke in the Czech RepublicJ. Siegelova (Brno, Czech Republic)

189. Analysis of arterial hypertension and obesity in Bulgarian young men in recruitment age (17-20)E. Anev, K. Ramshev (Sofia, Bulgaria)



190. Effects of weather in patients with hypertensionS. Gall (Budapest, Hungary)

191. Hypertension as a risk factor in the acute myocardial infarction in young patientsM.L. Chayán Zas, T.C. Gómez Cerqueiro, A. Pose Reino, M. Jaquet Herter, M. Gil de la Peña(Santiago, Spain)

192. Paget’s disease of bone and arterial hypertensionS. Voyaki, A. Efstratopoulos, A. Baltas, S. Siasiakou, L. Mourgos, V. Lekakis, E. Tsougos*, S. Psarakis*, M. Meikopoulos (Athens, Greece)


PharmacologicalTreatmentPoster Session 18


193. Reduction of left ventricular mass in essential hypertension: final results by meta-analysisincluding all randomized double-blind studies until September 2002A.U. Klingbeil, M. Schneider, P. Martus*, F.H. Messerli**, R.E. Schmieder (Nuernberg and *Berlin,Germany; **New Orleans, USA)

194. Comparison between two ways to apply “ABCD” strategy to control blood pressure in previouslyuntreated hypertensive patientsX. Girerd, J.P. Fauvel, Th. Denolle, J. Covillard, J. Fourcade, A. Marquand, P. Laurent, O. Hanon (Paris,France)

195. Time trends in the use of antihypertensive medications in primary care in SpainL. Garcia Ortiz, P.L. Sanchez Fernandez, I. Santos Rodriguez, E. Ramos Delgado, L.J. Gonzalez Elena,J. Barco Morillo, M.J. Barrientos Montero, A. Gomez Garcia, S. Hernandez Sanchez, M.J. Rodriguez Rivera (Salamanca, Spain)

196. Use of the missed-dose technique to assess the antihypertensive effect of the combination ofperindopril 4mg + Indapamide 1.25 mgM. Myers, F. Leenen*, J. Tanner (Toronto and *Ottawa, Canada)

197. THE MITEC study: intima media thickness evaluation with candesartan baseline dataS. Nisse-Durgeat, J.P. Baguet*, L. Avril, P. Valensi**, R. Asmar***, J.M. Mallion (Puteaux,*Grenoble, **Bondy and ***Paris, France)

198. Duration of action and BP lowering after one dose omission of amlodipine and valsartan inhypertensive patientsA. Radauceanu, J-M. Boivin, C. Bernaud*, F. Zannad (Nancy and *Paris, France)

199. Assessment of the persistence of the antihypertensive effect of a first line low-dose combinationof perindopril 2mg + indapamide 0.625 mg using the missed dose techniqueM. Myers, F.H.H. Leenen*, J. Tanner (Toronto and Ottawa, Canada)

200. Comparison of the efficacy and safety of a losartan-based versus an amlodipine-based regimenin patients with isolated systolic hypertensionM. Volpe, Z. Junren*, T. Maxwell**, A. Rodriguez***, R. Gambo***, P. Gomez-Fernandez°, R. Smith°° (Rome, Italy; *Shanghai, China; **Bexhill-on-Sea, UK; ***Lima, Peru; °Murcia, Spain;°°Whitehouse Station, NJ, USA)

201. Time of administration versus increasing dose of doxazosin GITS for improved blood pressurecontrol in patients with refractory hypertensionC. Calvo*, R.C. Hermida, D.E. Ayala, J.E. Lopez*, M.J. Dominguez*, M. Covelo*, A. Mojon, J.R. Fernandez (Vigo and *Santiago, Spain)

202. Administration-time dependent effects of valsartan on the circadian blood pressure profile ofhypertensive patientsR. Hermida, C. Calvo*, D.E. Ayala, M.J. Dominguez*, M. Covelo*, A. Mojon, J.R. Fernandez, J.E. Lopez* (Vigo and *Santiago, Spain)

12.30-15.30

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203. Evaluation of drug therapy and blood pressure control in elderly hypertensives in primary care levelK.A.J. Al Khaja, R.P. Sequeira, A.H.H. Damanhori (Manama, Bahrain)

204. Effects of the first dose of lacidipine and of nifedipine GITS on timed blood pressure in essentialhypertensionR. Hernández-Hernández, L. Alcocer*, M.G. Meny**, A.J. Reyes**, for the LASTLHY SteeringCommittee** (Barquisimeto, Venezuela; *Mexico City, Mexico;**Montevideo, Uruguay)

205. Reduced incidence of oedema with the enalapril/nitrendipine fixed dose combinationA. Roca-Cusachs, C. Pontes*, J. Combalia* (Barcelona and *Sant Joan Despí, Spain)

206. Effect on office blood pressure differs between nebivolol and losartan when used at advocateddaily dosesL. Van Bortel, W. Mäkel*, F. Fici**(Ghent, Belgium; *Schaijk, The Netherlands; **Milan, Italy)

207. The effect of normodipin on cardiac microcirculation in the treatment of patients with essentialhypertensive patientsI. Alizade (Baku, Azerbaijan)

208. Comparative effects of the calcium antagonist manidipine and enalapril on blood pressure andmetabolic parameters in hypertensive type 2 diabetics patientsM. Luque and Spanish Investigators (Madrid, Spain)

209. Isolated systolic hypertension control in the elderly: efficacy and tolerabilty of irbesartanG. Ferraro, A.M. Agrati, G. Palmieri (Milan, Italy)

210. Electronic form of the 1999 WHO/ISH hypertension guidelinesJ. Peleska, Z. Anger, M. Tomeckova, A. Vesely, J. Zvarova (Prague, Czech Republic)

211. Blood pressure reduction and good tolerability - a paradox?A. Marx, A. Lichtenthal, C. Milbredt, R. Ott, R. Agrawal (Berlin, Germany)

212. Quality of life does not differ between nebivolol and losartanL. Van Bortel, W. Mäkel*, F. Fici** (Ghent, Belgium; *Schaijk, The Netherlands; **Milan, Italy)

213. Combination therapy including ACE-inhibitor and AII-receptor antagonist improves 24-h bloodpressure control in mild to moderate hypertensive patientsR. Costa, G. Zanolini, N. Colombini, G. Moschini, G. Damiani, S. Ettori, M. Crippa, R. Fariello(Brescia, Italy)

214. Administration-time dependent effects of doxazosin GITS on blood pressure in hypertensivepatientsR. Hermida, C. Calvo*, D.E. Ayala, M.J. Dominguez*, M. Covelo*, A. Mojon, J.R. Fernandez, J.E. Lopez* (Vigo and *Santiago, Spain)

215. Efficacy and safety of lercanidipine in combination with enalapril in HBP. Preliminary results ofthe Zanycontrol study groupV. Gil-Guillen*, J. Abellan, J. Llisterri**, C. Sanchis°, A. Navarro***, J. Merino* (Murcia, *Elche,**Alaguas, ***San Sebastian de los Reyes and °Algemesi, Spain)

216. Moxonidine possibly inhibits angiotensin converting enzyme inhibitor (ACEi)-Induced cough inpatients with essential hypertension. A multi-centre, open pilot studyC. Farsang, E. Finta, L. Kerkovits, I. Barna, J. Szegedi*, J. Nemes**, G. Kurta*** (Budapest,*Nyíregyháza, **Pécs and ***Berettyoujfalu, Hungary)



217. AT1 receptors blockade normalizes autonomic nervous pattern in essential hypertensivesI. Zarkos, I. Vrana, G. Livieratos, A. Mitropoulou, N. Nearchou, E. Thireos, D. Papamichael* (Athens, Greece; *Larnaca, Cyprus)

218. Novel effect of carvedilol on Ca2+ movement in renal tubular cellsC.P. Liu, H.T. Chang, C.R. Jan (Kaoshiung, Taiwan)

219. The extent of microalbuminuria reduction with indapamide SR in elderly hypertensive type 2diabetic patients: the NESTOR studyM. Marre, J. Garcia-Puig*, F. Kokot**, M. Fernandez***, G. Jermendy****, L. Opie°, V. Moyseev°°,A. Scheen°°°, C. Ionescu-Tirgoviste°°°°, H. Saldanha°°°°° (Paris, France; *Madrid, Spain;**Katowice, Poland; ***Mexico City, Mexico; ****Budapest, Hungary; °Cape Town, South Africa;°°Moscow, Russia; °°°Liege, Belgium; °°°°Bucharest, Romania; °°°°°Coimbra, Portugal)

220. Efficacy of Viagra® (sildenafil citrate) in men with erectile dysfunction, treated hypertension,and ischemic heart diseaseR. Fogari, D.B. Glasser**, J. Orazem**, G. Mancia* (Pavia and *Monza, Italy; **New York, NY, USA)

221. T/P (trough-to-peak) ratio and smoothness index in hypertensive patients treated with efonidipin,a new DHP-calcium antagonist, or amlodipinJ.M. Sempere, J. Abellán*, J. Laborda, C. Calvo**, J.L. Rodicio*** (Alicante, *Murcia, **Santiagode Compostela and ***Madrid, Spain)

222. Efficacy and safety of efonidipin, a new DHP-calcium antagonist, versus amlodipine, in mild tomoderate hypertensionJ.M. Sempere, J. Abellán*, J. Laborda, C. Calvo**, J.L. Rodicio*** (Alicante, *Murcia, **Santiagode Compostela and ***Madrid, Spain)

223. Evolution of pulse pressure with candesartan in mild-to-moderate hypertensive patientsS. Nisse-Durgeat, R. Asmar**, J.M. Mallion*, J.L. Imbs*** (Puteaux, *Grenoble, **Paris and***Strasbourg, France)

224. Baseline characteristics of the patients included in APROS-GR study. (Assessment of PrognosticRisk Observational Survey-GR)A. Achimastos, A. Tsakiris (Athens, Greece)

225. Lercanidipine in chronic renal failureN.R. Robles, J. Ocon*, F. Gomez-Campdera**, L. Pastor***, J. Herrera°, J. Vilatoro°° (Badajoz,*Barcelona, **Madrid, ***Zaragoza, °Oviedo and °°Castellon de la Plana, Spain)

226. Rationale and design of telmisartan. Effectiveness on left ventricular mass reduction (TELMAR)studyM. Friedrich, B. Dahlöf**, U. Sechtem*, T. Unger, M. Knecht***, R. Dietz, for the TELMARInvestigators (Berlin, *Stuttgart and ***Ingelheim, Germany; **Gothenburg, Sweden)

227. Candesartan/HCT in resistant arterial hypertension - The place of ambulatory 24-h bloodpressure and electronic compliance monitoringS. Uen, B. Weisser, H. Vetter, R. Duesing, T. Mengden (Bonn, Germany)

228. Efficacy and tolerance of candesartan cilexetil 16mg associated with hydrochlothiazide 12,5 mgin patients with uncontrolled hypertension treated by fixed drug combinationS. Nisse-Durgeat, B. Vaîsse (Puteaux and *Marseille, France)



229. Improvement in orthopnoea during treatment with nifedipine GITSM.J. Armas-Hernández, R. Hernández-Hernández, L. Alcocer*, A.J. Reyes**, for the LASTLHYSteering Committee (Barquisimeto, Venezuela; *Mexico City, Mexico; **Montevideo, Uruguay)

230. Relation of thrombo-haemorrhagical complications with platelets activity and action of prazosinin patients with paroxysmal hypertensionG. Potapova, L. Bourjachkovskaya, V. Sitina, I. Uchitel (Moscow, Russia)

231. Synergistic effect of sesame oil with nifedipine on blood pressure, lipid peroxidation andantioxidants status in hypertensive patientsG.S Kamlakkannan, D. Sankar, G. Sambandam, M. Ramakrihna Rao, K.V. Pugalendi (Chidambaram,India)


Clinical AspectsPoster Session 19


232. Relations of arterial compliance to left ventricular geometry and systolic function and day-nightarterial pressure profile in hypertensive subjectsV. Palmieri, E. Arezzi, M. Sabatella, G. Di Minno, A. Celentano (Naples, Italy)

233. Efficacy of a quality improvement intervention in antihypertensive drugs prescription and bloodpressure controlL. Garcia Ortiz, I. Santos Rodriguez, P.L. Sanchez Fernandez, M. Gomez Marcos, L. Gonzalez Elena,J. Barco Morillo, M.J. Barrientos Montero, A. Gómez García, S. Hernández Sánchez, M.J. Rodríguez Rivera (Salamanca, Spain)

234. Should a routine echocardiogram with all low and medium risk hypertensives be performed?C. Suarez, J. Villar, N. Martel, B. Gil Extremera, N. Sullivan, C. Campo, V. Castellanos, A. Liébana, N. Rodilla, J. Nieto (Madrid, Spain)

235. Diastolic diurnal hypertension is a common and underestimated situation in patients withunknown hypertension at time of sleep apnea diagnosisJ.P. Baguet, J.L. Pepin, L. Hammer, H. Pierre, P. Levy, J.M. Mallion (Grenoble, France)

236. D-dimers and hypertensionT. Drossos, A. Loli, A. Regli, P. Doukas, P. Giaouris, I. Kaltsi, C. Vlachou, I. Constantinides (Athens, Greece)

237. White-coat compliance: an important confounding factor in assessing drug efficacy in clinical studies M. Burnier, M. Bochud, C. Falconnet, P. Bovet (Lausanne, Switzerland)

238. Increased inflammatory markers in salt sensitive hypertensionM. Larrousse, E. Bragulat, M. Sagarra, C. Sierra, A. Coca, A. De la Sierra (Barcelona, Spain)

239. Increased markers of oxidative stress in salt sensitive hypertensionM. Larrousse, E. Bragulat, R. Deulofeu, C. Sierra, A. Coca, A. De la Sierra (Barcelona, Spain)

240. Associated clinical conditions do not lead to improved blood pressure control in hypertensivepatients treated in general practiceA. Dyrdal, H.P. Stokke, H. Fagertun, I. Os (Oslo, Norway)

241. P wave dispersion based on surface 12-lead ECG and on ambulatory ECG as a predictor forparoxysmal atrial fibrillation in essential hypertensive subjectsA. Hatziyianni, C. Tsioufis, A. Arapogianni, V. Katsi, E. Taxiarchou, E. Tsiamis, I. Kallikazaros, C. Pitsavos, C. Stefanadis, P. Toutouzas (Athens, Greece)

242. Post-partum hypertension and non-steroidal analgesiaA. Makris, C. Thornton, A. Hennessy (Sydney, Australia)

243. Patient dietary recall underestimates sodium intakeA. Lieba, A. Vald, E. Peleg, E. Grossman (Tel-Hashomer, Israel)

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244. Isolated office hypertension: a 3 year follow-up studyA.M. Grandi, E. Cassinerio, D. Imperiale, E. Laurita, E. Barlocco, P. Saggiorato, A. Bertolini, F. Piperno, L. Guasti, A. Venco (Varese, Italy)

245. Does the type of microvascular compression of medulla oblongata influence the severity ofhypertension?P. Légrády, Gy. Ábrahám, P. Barzó, E. Vörös, A. Letoha, S. Sonkodi (Szeged, Hungary)

246. Arterial stiffness and left ventricular hypertrophy in untreated middle-aged hypertensive malesT. Ristimäe, P. Kampus, P. Muda, M. Zilmer, R. Teesalu (Tartu, Estonia)

247. Newly diagnosed hypertensives have poor prognostic markersK. Yusoff, A. Rapaee, M.N. Norafaedah, H. Nawawi (Kuala Lumpur, Malaysia)

248. Physical training in water and physical exercise tolerance of arterial hypertension patientsS. Shahvorostova, N. Shinkarenko, G. Moltchanova, Ju. Janikina, O. Êiseleva (Moscow, Russia)

249. Favorable effects of torasemide in heart failure patients pretreated with furosemide regardingbodyweight and plasma potassium levelA. Lichtenthal, C. Milbredt, A. Marx, R. Agrawal (Berlin, Germany)

250. Experiences with the dihydropyridine calcium channel blocker amlodipine in hypertensivepatients with chronic renal failureP. Légrády, Gy. Ábrahám, A. Letoha, S. Sonkodi (Szeged, Hungary)

251. Factors influencing on normal blood pressure in ambulatory blood pressure measurementT. Grodzicki, J. Kocemba, A. Adamkiewicz-Piejko, B. Wizner, J. Gasowski, A. Olszanecka, J. Zyczkowska, K. Kawecka-Jaszcz (Cracow, Poland)

252. Carotid endothelial abnormalities are related to poor control of systolic rather than diastolicblood pressureA. Tsakiris, M. Doumas, N. Nearchos, K. Kyriakou, K. Flessa, A. Giannakopoulou, P. Skoufas (Athens, Greece)

253. Blood pressure control with monotherapy in a Greek population: experience of an outpatienthypertension clinicA. Tsakiris, M. Doumas, N. Nearchos, I. Tsiafoutis, K. Flessa, D. Skoufas, P. Skoufas (Athens, Greece)

254. Essential hypertension and development of cardiovascular complicationsA.A. Pavlov, B.A. Namakanov (Moscow, Russia)

255. Five year results of treatment hypertensive patients in specialised hypertension unitG. Radchenko, Yu. Sirenko (Kiev, Ukraine)

256. Effect of time of antihypertensive drugs administration on blood pressure response to exercise inhypertensive patientsA. Niklas, M. Mastej, P. Lopatka, O. Trojnarska, A. Tykarski (Poznan, Poland)

257. Plasma fibrinogen associates with left ventricular mass index in untreated hypertensive malesT. Ristimäe, P. Muda, P. Kampus, M. Zilmer, R. Teesalu (Tartu, Estonia)

258. QT interval variability and T wave alternans in hypertensive subjects with left ventricularhypertrophyV. Popov, N. Bulanova, N. Kopitsa*, L. Malaya*, A. Radzevich, T. Mischeryakova, O. Zerbini**(Moscow, Russia; *Kharkow, Ukraine; **Verona, Italy)


ExperimentalPharmacology andHypertensionPoster Session 20


259. Enalapril prevents and reverses cardiac hypertrophy and oxidative stress associated withangiotensin II hypertension in the ratC. Rugale, M. Cordaillat, A. Mimran, B. Jover (Montpellier, France)

260. Wine polyphenols increase NO synthase expression and its activity in both normotensive andhypertensive ratsO. Pechanova, I. Bernatova, W. Zenebe, R. Andriantsitohaina* (Bratislava, Slovak Republic; *Illkirch,France)

261. Systemic gene transfer of oxidant stress genes and blood pressure in a model of genetichypertensionW.H. Miller, D. Graham, M.J. Brosnan, A.J. Frater, K. Channon*, P.N. Reynolds**, A.H. Baker, A.F. Dominiczak (Glasgow and *Oxford, UK; **Adelaide, Australia)

262. Hypotrophy of conduit artery wall in offspring of nitric oxide defective ratsF. Kristek, M. Gerova, M. Lehotsky* (Bratislava and *Hlohovec, Slovak Republic)

263. The cross-talk of nitric oxide, angiotensin II and free oxygen radicals in experimentalhypertensionO. Pechanova, I. Bernatova, D. Capikova, I. Zavillova (Bratislava, Slovak Republic)

264. Role of afferent renal nerve fibers in genetic and secondary hypertensionP. Linz, A. Kerstin, W. Freisinger, K.F. Hilgers, R. Veelken (Erlangen, Germany)

265. AT1 Receptors in the RVLM do not play a significant role in maintaining high blood pressures0observed in renovascular hypertensive ratsV. Reja, J.M. Makeham, A.K. Goodchild, P.M. Pilowsky (Sydney, Australia)

266. Chronic high-fat diet administration delays cardiovascular recovery from stress and promotes thedevelopment of eccentric left ventricular hypertrophy in spontaneously hypertensive ratsL. Sedova, J. Berube, D. DeBlois, J. Tremblay, P. Hamet, Z. Pausova (Montreal, Canada)

267. Role of endogenous adrenomedullin system in the regulation of secretion and growth of ratadrenal cortexG.P. Rossi, M.T. Conconi, K.L. Malendowicz*, G.G. Nussdorfer (Padua, Italy; *Poznan, Poland)

268. Effect of exogenous NO donors administration on reactivity and geometry of iliac artery of SHRF. Kristek, S. Kyselá (Bratislava, Slovakia)

269. Role of central alpha2-adrenoreceptors in blood pressure maintance in rats with differentgenesis of hypertensionN.A. Feldsherova, R.S. Chrustaleva, N.K. Merkulova, V.A. Tsyrlin (St. Petersburg, Russia)

270. Blood pressure variability and baroreceptor-heart rate reflex in rats fed high sodium dietsJ. Blanc, M. Cordaillat*, S. Laurent, J.L. Elghozi, B. Jover* (Paris and *Montpellier, France)

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271. Geometry of carotid artery in Wistar and spontaneously hypertensive rats during ontogenesisF. Kristek, M. Urminska (Bratislava, Slovak Republic)

272. Role of angiotensin II and oxidative stress in renovascular hypertensionY. Otsuka, S. Harasawa, H. Sugiura, H. Abeta, T. Okabe, T. Kushiro, K. Kanmatsuse (Tokyo, Japan)

273. Metabolic disorders and its role in the treatment of hypertensionL. Illyes (Miskolc, Hungary)

274. Severe carotid barochemoreceptor involvement in strokeJ. Milei, A. Lavezzi*, D. Grana, F. Silvestri**, R. Bussari**, L. Rossi*, L. Matturri* (Buenos Aires,Argentina; *Milan and **Trieste, Italia)

275. Relationship between baroreflex sensitivity and oxidative stress in healthy and hypertensivepatientsO. Ormezzano, J.L. Cracowski, P. François, J.P. Baguet, J.M. Mallion (Grenoble, France)

276. Metabolic response to salt overload and restriction: is gender a determinant factor?G. Patriarca, L. Furukawa, J. Heimann (São Paulo, Brazil)

277. Vascular antioxidant enzyme activity in experimental hypertension with activation of the reninangiotensin system T. Sousa, M. Morato, E. Fernandes, F. Carvalho, A. Albino-Teixeira (Porto, Portugal)

278. Cardiopulmonary baroreflex sensitivity and heart rate variability in hypertensive patients duringacute pharmacological tests: rilmenidine vs atenololA. Konrady, O. Mamontov, A. Shavarov, Y. Kasherininov (Saint Petersburg, Russia)

279. ST segment depression criteria and the prevalence of silent cardiac ischemia in hypertensivesD. Boon, J. van Goudoever, J.J. Piek, G.A. van Montfrans (Amsterdam, The Netherlands)

280. Role of endothelin in the stimulation of NAD(P)H oxidase and superoxide production in vascularsmooth muscle cells following a treatment with angiotensin IIM. Laplante, R. Wu, P. Moreau, J. de Champlain (Montreal, Canada)

281. Beneficial effect of pentaerythrityl tetranitrate in experimental hypertensionF. Kristek, J. Török, I. Varga* (Bratislava and *Hlohovec, Slovak Republic)

282. Protective effect of telmisartan in cardiac tissueH. Nolly, I. Raposo, M. Nolly (Mendoza, Argentina)

283. Hypotensive-independent effects of nifedipine on the endothelial function inhypercholesterolemic rabbitsA. Lopez-Farre, S. Alonso-Orgaz, C. Carrasco, P.J. Mateos-Cáceres, A. García-Mendez, M.R. Ramón-Albalate, C. Abarrategui-Garrido, S. Casado (Madrid, Spain)

284. The effect of nebivolol on the altered vascular reactivity of the renal artery in diabetic mouseE. Badila, A. Georgescu, D. Popov, M. Dorobantu, M. Simionescu (Bucharest, Romania)

285. Effects of quinapril and losartan on renal microcirculation and renal hemodynamics inciclosporine A treated ratsU. Hillebrand, H. Hohage, B. Suwelack (Muenster, Germany)



286. Very low dose perindopril/indapamide combination fully protects obese rat kidney structure andfunctionI.M. Renaud, A. Chainey*, J. Chavalier, G.E. Plante* (Paris, France; *Quebec, Canada)

287. Eplerenone: a selective aldosterone blockerM-E. Rafestin-Oblin, A. Rudolph*, J. Fagart (Madrid, Spain; *Skokie, USA)

288. The effect of captopril thiol group in the prevention of hypertensionO. Pechanova, D. Capikova (Bratislava, Slovakia)

289. Biochemical consequences of acute NO blokade and ET-1 infusion in Wistar ratsT. Popovic, Dj. Jovovic, Z. Miloradovic, N. Mihailovic-Stanojevic (Belgrade, Yugoslavia)

290. Ascorbic acid does not affect adrenocorticotrophic hormone (ACTH)-induced hypertension in ratsC.G. Schyvens, M.C. Andrews, Y. Zhang, K.U.S. McKenzie, J.A. Whitworth (Canberra, Australia)

291. Allopurinol does not prevent or reverse ACTH-induced hypertension in Sprague-Dawley ratsY. Zhang, M.M.K. Chan, M.C. Andrews, C.G. Schyvens, K.U.S McKenzie, J.A. Whitworth (Canberra,Australia)

292. Specific effect of acute interleukin-10 inhibition on maternal blood pressure in pregnanttelemetered papio hamadryasS. Orange, A. Hennessy, J. Horvath, J Vaughan, J. Thompson (Sydney, Australia)

293. The onset of hypertension is preceded by overexpression of renal LAT2 and enhanced tubularuptake of dopamineprecursor M.J. Pinho, P. Gomes, M.P. Serrao, M.J. Bonifacio*, P. Soares-da-Silva (Porto and *S. Mamede doCoronado, Portugal)

294. Diguanosine pentaphosphate induces proliferation via P2Y receptors activating RHO-kinaseZ. Zhu*, S. Zhu*, D. Liu*, M. van der Giet, M. Tepel (Berlin, Germany; *Chongqing, China)

295. SHR renal proximal tubules respond to dopamine D3 receptor stimulation with inhibition of theNA+/H+ exchangerR. Pedrosa, P. Soares-da-Silva (Porto, Portugal)

296. Decreased tyrosine hydroxylase activity in the adrenals of spontaneous hypertensive ratsM. Vieira-Coelho, E. Moura (Porto, Portugal)

297. Decreased ATP synthesis ability of liver mitochondria in spontaneously hypertensive ratsY. Budnikov, A. Postnov, A. Doroschuk, G. Afanasjeva, Y. Postnov (Moscow, Russia)

298. Strain differences in the degree of hypertension and glomerulosclerosis induced bydeoxycorticosterone acetate-salt in miceR. Veelken, N. Cordasic, B. Klanke, K.F. Hilgers, A. Hartner (Erlangen, Germany)

299. The hypotensive effect of ferulic acid, a phytochemical constituent, is associated with nitricoxide-mediated vasodilation in SHRA. Suzuki, D. Kagawa, A. Fujii, R. Ochiai, I. Tokimitsu, I. Saito* (Tochigi and *Tokyo, Japan)

300. Lead-induced downregulation of soluble guanylate cyclase in isolated aortic segments mediatedby reactive oxigen species and cyclooxigenase-2A. Lopez-Farre, E. Courtois, M. Marquez*, A. Barrientos, S. Casado (Madrid, Spain)



301. Hypertensive response to chronic L-NAME treatment is similar in immature and adult Wistar ratsJ. Zicha, Z. Dobesova, O. Pechanova*, J. Kunes (Prague, Czech Republic; *Bratislava, SlovakRepublic)

302. Up regulation of the adrenomedullin system mediates hypotension and hypoaldosteronisminduced by simulated microgravityP.G. Andreis, G.P. Rossi, S. Bova, L.K. Malendowicz*, G. Mazzocchi, G.G. Nussdorfer (Padua, Italy;Poznan, Poland)

303. The role of the caudal ventrolateral medulla in the hypoalgesia associated with hypertensionM. Morato, T. Sousa, I. Tavares, A. Albino-Teixeira (Porto, Portugal)

304. Catecholamine concentration and lymphocyte beta-2-adrenoceptor dependent cAMP synthesis inPrimary Pulmonary Hypertension patientsT. Arefieva, N. Irodova, T. Krasnikova, V. Masenko, I. Chazova (Moscow, Russia)


PharmacologicalTreatmentOral Session 6A


ChairmenB. Krupa-Wojciechowska (Gdansk, Poland)L.C. Rump (Herne, Germany)

15.30 The interaction between aspirin and losartan on cardiovascular morbidity and mortality inpatients with hypertension and left ventricular hypertrophy. A losartan intervention for endpointreduction (LIFE) StudyE. Fossum, S.E. Kjeldsen, B. Dahlöf*, R.B. Devereux**, S. Julius***, S. Snappin**** (Oslo and*Göteborg, Sweden; **New York, NY, ***Ann Arbor, MI, and ****New Jersey, USA)

15.45 Assessment of angiotensin converting enzyme inhibition and compliance to treatment by urinaryacSDKP in the Diabhycar studyM. Azizi, A. Bissery, G. Chatellier, M. Marre, J. Ménard, and DIABHYCAR Investigators (Paris,France)

16.00 A comparison of the effects of a 7-day period of non-compliance on blood pressure control using3 different antihypertensive agentsB. Girvin, T. Rafferty, G.D. Johnston (Belfast, UK)

16.15 Addition of irbesartan in type 2 diabetic patients treated with ACE inhibitors with persistentmicroalbuminuria and uncontrolled hypertension: the AIMEE trialF.J. Martínez-Martín (Las Palmas de Gran Canaria, Spain)

16.30 The angiotensin II antagonist irbesartan is superior to the dihydropyridine calcium-channelblocker amlodipine in childhood chronic kidney disease with overt proteinuriaM.G. Bianchetti, R.O. von Vigier, E. Fossali*, A. Edefonti* (Berne, Switzerland; *Milan, Italy)

16.45 Implications of the final results of LIFE, AASK and ALLHAT for antihypertensive treatment inblack people. A Cochrane systematic reviewL. Brewster, G. van Montfrans, J. Kleijnen* (Amsterdam, The Netherlands; *York, UK)

Yellow Hall

Sunday, June 15


Renin-Angiotensin SystemOral Session 6B


ChairmenM. Safar (Paris, France)S. Taddei (Pisa, Italy)

15.30 Angiotensin II directly contributes to atherosclerosis progression, beyond its pressure effect, inApoE -/- miceL. Mazzolai, M. Moratel, K. Bouzourene, J.F. Aubert, H. Hiroyuki, G. Gabbiani, H. Brunner, J. Nussberger, D Hayoz (Lausanne, Switzerland)

15.45 Dose-dependent effects of eplerenone on the renin-angiotensin-aldosterone system and bloodpressure in hypertensive patientsJ. Menard*, F. Yang, R. Bittman (Skokie, USA; *Paris, France)

16.00 Selective AT1 receptor antagonism enhances sympathetically mediated vasoconstriction in manD. Lyons, S.H.D. Jackson, C. Swift (Limerick, Ireland)

16.15 Angiotensin II induces endothelial nitric oxide synthase in PC12W cells via AT2 receptoractivationY. Zhao, U. Kintscher, E. Kaschina, P. Gohlke*, T. Unger (Berlin and *Kiel, Germany)

16.30 The angiotensinogen genotype affects hypertension in mice and predicts the hypotensiveresponse to AT1 receptor antagonismC. Handtrack, B. Klanke, N. Cordasic, R.E. Schmieder, R. Veelken, K.F. Hilgers (Erlangen, Germany)

16.45 Dual versus single blockade of the renin-angiotensin system in hypertension: haemodynamicand hormonal consequencesA. van den Meiracker, J. Deinum, F. Boomsma (Rotterdam, The Netherlands)

Red Hall 1

Sunday, June 15


EndotheliumOral Session 6C


ChairmenD. Hayoz (Lausanne, Switzerland)W. Kiowski (Zurich, Switzerland)

15.30 Markers of inflammation, endothelial function and blood pressure in untreated essentialhypertensive L. Ghiadoni, V. Panichi, D. Versari, I. Kardasz, P. Duranti, A. Magagna, G. Salvetti, S. Taddei,A. Salvetti (Pisa, Italy)

15.45 L-S -nitrocysteine: an endothelium-derived hyperpolarizing factor in porcine coronary arteries?A. Danser, R. de Vries, W. Batenburg, P. Saxena (Rotterdam, The Netherlands)

16.00 Mechanisms involved in the protective effects of eplerenone on hypertensive endothelialdysfunction and arterial remodellingE. Cediel, D. Sanz-Rosa, N. de las Heras, P. Aragoncillo, R. Rocha*, V. Cachofeiro, V. Lahera(Madrid, Spain; *Skokie, USA)

16.15 Endothelial cell beta-2 adrenergic receptor stimulation cause ERK activation and cellproliferationG. Iaccarino, E. Cipolletta, D. Sorriento, B. Trimarco (Naples, Italy)

16.30 LECTURE:Endothelium derived hyperpolarizing factor: combining the concepts and exploring themechanismsR. Busse (Frankfurt, Germany)

Red Hall 2

Sunday, June 15



15.30-17.00 Topical Workshop

Cardiovascular effects of obstructive sleep apnea

Chairmen:J. Hedner (Goteborg, Sweden)K. Narkiewicz (Gdansk, Poland)

Opening remarksJ. Hedner (Goteborg, Sweden)

Overview of the latest epidemiological dataC. Lombardi and P. Cortelli (Bologna, Italy)

How to assess the cardiovascular effects of obstructive sleep apnea?G. Parati (Milan, Italy)

Sympathetic neural mechanisms in sleep apneaK. Narkiewicz (Gdansk, Poland)

Vasculopathy in obstructive sleep apneaJ. Hedner (Goteborg, Sweden)

Blue Hall

Sunday, June 15



17.00-18.30 Plenary Session

17.00 Presentation of Awards

Chairmen :A.M. Heagerty (Manchester, UK)J.L. Rodicio (Madrid, Spain)

Björn Folkow AwardF.C. Luft (Berlin, Germany)

Alberto Zanchetti AwardA.F. Lever (Glasgow, UK)

Lennart Hansson AwardS. Julius (Ann Arbor, MI, USA)

Servier SNS Research Award of ESHM. Schlaich (Erlangen, Germany)

17.15 Björn Folkow Award LectureWhat can we learn from autosomal-dominant hypertension with brachydactyly?F.C. Luft (Berlin, Germany)

17.45 Lennart Hansson Memorial LectureOutcomes studies in hypertension - New agenda for the new centuryS. Julius (Ann Arbor, MI, USA)

18.30 European Society of Hypertension Business Meeting

Auditorium

Sunday, June 15

Documents

Thirteenth European Meeting on Hypertension Milan (Italy ...THIRTEENTH EUROPEAN MEETING ON HYPERTENSION 111 Thirteenth European Meeting on Hypertension Milan (Italy), June 13 / 17,