Attain the optimal combination of chromatographic speed and resolution using the new Thermo Scienti� c™ Dionex™ IonPac™

AS18-4µm anion-exchange column. This high-capacity, high-ef� ciency column provides excellent resolution of

inorganic anions in diverse sample matrices. Compared to the previous Dionex IonPac AS18-Fast column, the new

ion-exchange column uses smaller resin particles for more ef� cient separations resulting in faster run times, more

accurate peak integration and more reliable results.

Dionex IonPac AS18-4µm Anion-Exchange Column (0.4 x 150, 2 x 150 and 4 x 150 mm), AG18-4µm (0.4 x 35, 2 x 30 and 4 x 30 mm)

• Decrease run times, increase sample throughput without loss of resolution

• Fast isocratic separations of inorganic anions in drinking water, wastewater and other diverse sample matrices

• Excellent for environmental customers needing to improve productivity

• For fastest runs and optimal performance, a Thermo Scientifi c™

Dionex™ ICS-5000+ Reagent-Free™ HPIC™ or Dionex ICS-4000 Capillary HPIC system is required

Thermo Scientifi c Dionex IonPac AS18-4µm Column

Highlights

Product Spotlight

Minutes

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Peaks: 1. Fluoride 0.2 mg/L 2. Chloride 0.5 3. Nitrite 1.0 4. Sulfate 1.0 5. Bromide 1.0 6. Nitrate 1.0 7. Phosphate 2.0

Figure 1. Fast separation of inorganic anions using the Dionex IonPac AS18-4µm capillary column

Figure 1 shows the excellent peak effi cien-cies produced by the Dionex IonPac AS18-4 µm capillary anion-exchange column. Because of the improved effi ciency, the fl ow rate can be increased to 30 µL/min reducing the analysis time to less than 3 minutes without a loss in resolution. Sample throughput can be dramatically increased without compromising the quality of the analysis.

Product Spotlight

The Dionex IonPac AS18-4µm column is ideal for analyzing inorganic anions in diverse sample matrices, including drinking water, wastewater and food and beverage samples. Figure 2 shows the analysis of municipal drinking water spiked with chlorite and chlorate using the Dionex IonPac AS18-4µm capillary column. Excellent resolution is maintained in this drinking water sample even at the increased fl ow rate of 30 µL/min, allowing easier peak integration and more accurate results.

For more information,

visit www.thermoscientifi c.com/4um or

email us at analyze@thermoscientifi c.com

Figure 3. Comparison of resolution of nine inorganic anions using the Dionex

IonPac A) AS18-Fast (2 × 150 mm) column and B) AS18-4µm (2 × 150 mm)

column. The small particle column increases response and produces sharper

peaks with high column effi ciency

Figure 2. Analysis of municipal drinking water using the Dionex IonPac AS18-4µm

capillary column

Column: A: Dionex IonPac AS18-Fast, (2 × 150 mm) B: Dionex IonPac AS18-4 m, (2 × 150 mm)

Eluent Source: A: Dionex EGC III KOH B: Dionex EGC 500 KOH

Eluent: 23 mM KOH Flow Rate: 0.25 mL/min Inj. Volume: A: 5 L; B: 2.5 L Column Temp.: 30 °C Detection: Suppressed conductivity,

Dionex ASRS 300, 2 mm, recycle, 15 mA

Peaks: 1. Fluoride 0.5 mg/L

2. Chlorite 5.0 3. Chloride 3.0 4. Nitrite 5.0 5. Carbonate 20.0 6. Bromide 10.0 7. Sulfate 10.0 8. Nitrate 10.0 9. Chlorate 10.0

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©2013 Thermo Fisher Scientifi c Inc. All rights reserved. All trademarks are the property of Thermo Fisher Scientifi c Inc. and its subsidiaries.

SP70629_E 04/13S

Peaks: 1. Fluoride 0.1 mg/L 2. Chlorite 0.5 3. Chloride 33.5 4. Nitrite 2.4 5. Sulfate 118.9 6. Nitrate 18.5 7. Chlorate 0.5 8. Phosphate 1.0

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Smaller particles create more effi cient peaks as show in Figure 3. The top chromatogram was generated using the Dionex IonPac AS18-Fast column which uses a particle size of 7.5 µm. The bottom chromatogram was generated using the new Dionex IonPac AS18-4µm column, which uses 4 µm particles. Notice the sharper, taller peaks in the bottom chromatogram, even using half the injection volume, which allows the use of faster fl ow rates without a loss in resolution. The com-bination of faster fl ow rates with higher resolution provides increased sample throughput with more reliable results.

Did You Know?Many laboratories have pushed the existing 5.5–9 µm particle size columns to their limits of resolution and speed. Often increased fl ow rates cannot be used to speed up analyses because resolution and thus quality of results, suffer. For appli-cations requiring high resolution, it is not practical to improve resolution by using longer gradient runs due to the impact on sample throughput. Because the new IC columns are more effi cient, laboratories can optimize their separations to achieve higher resolution, or higher fl ow rates, or both simultaneously.

Product Spotlight

Column: A: Dionex IonPac AS18-Fast, (2 × 150 mm) B: Dionex IonPac AS18-4 µm, (2 × 150 mm)Eluent Source: A: Thermo Scientifi c™ Dionex™ EGC III KOH cartridge B: Dionex EGC 500 KOH cartridgeEluent: 23 mM KOHFlow Rate: 0.25 mL/minInj. Volume: A: 5 µL; B: 2.5 µLColumn Temp.: 30 °CDetection: Suppressed conductivity, Thermo Scientifi c™ Dionex™ ASRS™

300 Anion Self-Regenerating Suppressor™, 2 mm, recycle, 15 mA

Peaks: 1. Fluoride 0.5 mg/L 2. Chlorite 5.0 3. Chloride 3.0 4. Nitrite 5.0 5. Carbonate 20.0 6. Bromide 10.0 7. Sulfate 10.0 8. Nitrate 10.0 9. Chlorate 10.0