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Erwin R. Schmidt Institut für Molekulargenetik Vorlesung #4 12. 05. 2015 Thema Gentechnologie

Thema Gentechnologie - uni-mainz.de · TSC genes regulate growth, and it has been difficult to generate TSC transgenic mice with traditional methods (Potter et al., 2001; data not

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Page 1: Thema Gentechnologie - uni-mainz.de · TSC genes regulate growth, and it has been difficult to generate TSC transgenic mice with traditional methods (Potter et al., 2001; data not

Erwin R. Schmidt

Institut für MolekulargenetikVorlesung #4

12. 05. 2015

Thema Gentechnologie

Page 2: Thema Gentechnologie - uni-mainz.de · TSC genes regulate growth, and it has been difficult to generate TSC transgenic mice with traditional methods (Potter et al., 2001; data not
Page 3: Thema Gentechnologie - uni-mainz.de · TSC genes regulate growth, and it has been difficult to generate TSC transgenic mice with traditional methods (Potter et al., 2001; data not

Substitutionsvektoren

Linker Arm „Stuffer“ Rechter Arm

Integrat

Ligation

Page 4: Thema Gentechnologie - uni-mainz.de · TSC genes regulate growth, and it has been difficult to generate TSC transgenic mice with traditional methods (Potter et al., 2001; data not
Page 5: Thema Gentechnologie - uni-mainz.de · TSC genes regulate growth, and it has been difficult to generate TSC transgenic mice with traditional methods (Potter et al., 2001; data not
Page 6: Thema Gentechnologie - uni-mainz.de · TSC genes regulate growth, and it has been difficult to generate TSC transgenic mice with traditional methods (Potter et al., 2001; data not
Page 7: Thema Gentechnologie - uni-mainz.de · TSC genes regulate growth, and it has been difficult to generate TSC transgenic mice with traditional methods (Potter et al., 2001; data not
Page 8: Thema Gentechnologie - uni-mainz.de · TSC genes regulate growth, and it has been difficult to generate TSC transgenic mice with traditional methods (Potter et al., 2001; data not
Page 9: Thema Gentechnologie - uni-mainz.de · TSC genes regulate growth, and it has been difficult to generate TSC transgenic mice with traditional methods (Potter et al., 2001; data not
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Page 14: Thema Gentechnologie - uni-mainz.de · TSC genes regulate growth, and it has been difficult to generate TSC transgenic mice with traditional methods (Potter et al., 2001; data not
Page 15: Thema Gentechnologie - uni-mainz.de · TSC genes regulate growth, and it has been difficult to generate TSC transgenic mice with traditional methods (Potter et al., 2001; data not
Page 16: Thema Gentechnologie - uni-mainz.de · TSC genes regulate growth, and it has been difficult to generate TSC transgenic mice with traditional methods (Potter et al., 2001; data not
Page 17: Thema Gentechnologie - uni-mainz.de · TSC genes regulate growth, and it has been difficult to generate TSC transgenic mice with traditional methods (Potter et al., 2001; data not
Page 18: Thema Gentechnologie - uni-mainz.de · TSC genes regulate growth, and it has been difficult to generate TSC transgenic mice with traditional methods (Potter et al., 2001; data not
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Page 20: Thema Gentechnologie - uni-mainz.de · TSC genes regulate growth, and it has been difficult to generate TSC transgenic mice with traditional methods (Potter et al., 2001; data not

P-Elemente sind Transposons bei D. melanogaster, die eine Keimbahn-spezifisch aktive Transposase exprimieren

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PiggyBac-Transposon aus Trichoplusia ni (Schmetterling) funktioniert in einer großen Bandbreite von Organismen inklusive der Maus

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