The Whole World of Ion Chromatography...Tubing for Peristaltic Pumps 38 782 IC Column Thermostat 39 837 IC Sample Degasser 40 6.2836.000 IC Post-Column Reactor 41 Liquid Handling 820

The Whole World of Ion Chromatography

I o n a n a l y s i s

2

In a class of its own: the new Advanced IC fromMetrohm. It is based on the high-performance modular Metrohm IC System, but the central systemcomponents have been thoroughly reworked andextended. Both the software and hardware havebeen significantly improved, so that with the Advanced IC an even better performance in anionand cation analysis can be achieved – both with and without chemical suppression.

With immediate effect the serial 818 Dual-PistonHigh-Pressure Pump is now equipped with a latestgeneration of electronic controls. Eluent flow is extremely precise and practically pulsation-free. The820 IC Separation Center has been extended byincluding autonomous column heating; this ensuresthe optimal temperature stability of the whole system. The analog output signal of the 819 IC De-tector is now transferred to the optically decoupled A/D converter of the 830 IC Interface via a speciallyshielded D-sub-9 cable. This reliably prevents external interferences from affecting the system.

There are also clear changes in the software: IC Net2.3 sees the introduction of IC Cap. This new adapt-able user interface simplifies the operation of the IC system: «analysis with a single mouse-click». Theoperation and control of even complex systems isnow child’s play. In the background the «ProtectedProtocol» ensures and optimizes communicationbetween the system components. The implementedstatistics functions increase user-friendliness. Thelatest version of the Metrodata IC software is

completely compliant with «21 CFR Part 11» as a matter of course.

The innovative system solution Metrohm AdvancedIC is completely PC-controlled. The number of con-trols on the instruments has been reduced to theabsolute minimum. Wet chemistry has been com-pletely separated from the electronics and controls.

The highest possible degree of functionality, logicalconstruction and intelligent software make yourintroduction to ion chromatography with Metrohmeasy. In schools and universities the Compact BasicIC shows just how uncomplicated ion chromato-graphy can be. With a minimal amount of training the modular and online instruments can be safelymastered in the laboratory or in production. Thismeans that on the one hand it is a pleasure to workwith Metrohm IC instruments, on the other handthey help to reduce costs in a very effective manner.

You will obtain reliable instruments with a long working life from Metrohm, no matter whether you decide on a Compact Ion Chromatograph, theAdvanced IC System or one of the two Online ICs.Regardless of whether with or without automation,all IC systems are characterized by the perfect inte-gration of all individual components, with or withoutsuppression. This guarantees minimal down time for service and maintenance. Thanks to high qualitystandards and intelligent product design, the operating costs are decidedly low. In addition, theMetrohm anion suppressor «MSM» comes with a 10years' warranty. You will not find a price for a cationsuppressor anywhere, as this is not necessary withMetrohm products.

Metrohm has been supplying the complete field ofion analysis from a single source for more than 50years. This is why Metrohm is always able to supplyyou with the optimal solution to your individual analytical problems.

Ion chromatography – really easy with Metrohm

The Whole World of Ion Chromatography

3

• My three-year-old can do it • Today, IC is just one mouse click away• Easy to use wherever you are• Metrohm Ion Chromatography• Speaks ten languages

For more information see page 54

Compact IC Systems761 Compact IC 7790 Personal IC 8792 Basic IC 9

Metrohm Compact IC – important differences at a glance 10

Modular IC Systems«MIC-1 Advanced» – Modular anion or cation system with electronic suppression 11

«MIC-2 Advanced» – Modular anion system with chemical suppression 12

«MIC-3 Advanced» – Modular anion and cation system with chemical suppression 13

Metrohm Inline Sample Preparation «MISP» 14

«MIC-4 Advanced» – Modular cation system with electronic suppression and sample preconcentration 15

«MIC-5 Advanced» – Modular anion system with chemical suppression and sample preconcentration 16

«MIC-6 Advanced» – Modular anion system with chemical suppression, sample preconcentration and matrix elimination 17

«MIC-7 Advanced» – Modular anion system with chemical suppression and dialysis 18

«MIC-7 Compact» – Compact anion system with chemical suppression and dialysis 19

«MIC-8 Advanced» – Modular system with 817 Bioscan for sugar analysis 20

«MIC-9 Advanced» – Combined modular system for anions and sugar analysis 21

«MIC-10 Advanced» – Binary high-pressure gradient system for the determination of anions with chemical suppression 22

Online IC Systems811 Online IC Process Analyzer 23821 Compact Online IC Process Analyzer 24

Metrohm IC Systems

4

5

Detectors819 IC Detector 25

Noise 26791 IC-VA Detector 27817 Bioscan 28

Pumps818 IC Pump 29833 IC Liquid Handling Pump Unit 30

Suppressors833 IC Liquid Handling Suppressor Unit 31

Reproducibility 32828 IC Dual Suppressor 33

Sample Preparation833 IC Liquid Handling Sample Preparation Unit 34833 IC Liquid Handling Dialysis Unit 35

Dialysis 36833 IC Liquid Handling Ultrafiltration Unit 37

Tubing for Peristaltic Pumps 38782 IC Column Thermostat 39837 IC Sample Degasser 40

6.2836.000 IC Post-Column Reactor 41

Liquid Handling820 IC Separation Center 42812 Valve Unit 43

6.5904.0X0 Internal Loop 44816 IC Eluent Selector 45837 IC Eluent Degasser 46837 IC Combi Degasser 47

Sample Changers788 IC Filtration Sample Processor/ 788 IC Dialysis Sample Processor 48/49766 IC Sample Processor 50813 Compact IC Autosampler 51

Interfaces and Software830 IC Interface 52771 IC Compact Interface 52

Metrodata IC Cap Software 53Metrodata IC Net Software 54Metrodata AutoDatabase Software 54

Applications 55IC Newsletter 55

Metrohm IC Modules

Compact ICAdvanced IC

Online IC Table of Contents

Metrohm IC Systems

Compact IC Systems

Advanced IC Systems

Small instruments – high quality: the Metrohm compact class contains everything that an efficiention chromatograph requires: dual-piston pump, pulsation absorber, electromagnetic injection valve,peristaltic pump, high-performance detector, eluentorganizer as well as a data acquisition and process-ing module. All components which come into contact with the sample or eluents are metal-free.

With an extremely small footprint and a height ofonly 45 cm the Metrohm Compact IC Systems con-tain the maximum of IC in the minimum of space:

• Injection valve

• IC Pump – extremely low-pulsation dual-pistonpump with a flow range of 0.2 to 2.5 mL/min and a maximum pressure of 25 MPa (250 bar); a connection for an external compressed gas supplyis not necessary

• Pulsation absorber – even with low-level pressurevariations the pulsation absorber reliably protectsyour column against damage

• Column compartment – the perfect insulation of the housing not only creates thermally stable conditions for the columns, it also shields the system against electromagnetic interference

• Columns – no matter whether anion columns withor without chemical suppression, cation columnsor separating columns for organic acids – theCompact IC Systems have space for all of them

• Suppressor – the «MSM» Metrohm SuppressorModule is already included in the instrument ver-sions for chemical suppression. Pressure resistant,with fully automatic regeneration, high perform-ance, top reproducibility and – last but not least –a long working life: the «MSM» is and remainsthe suppressor of choice

• Peristaltic pump – the «MSM» is regenerated and rinsed by backflushing resulting in maximumuptime

• Detector block – the heart of the instrument with built in high precision temperature controland additional insulation

With these favorably-priced and compact ion chro-matographs Metrohm has opened up IC as a routineanalytical tool at a cost all laboratories can afford.

6

The Metrohm IC Systems mentioned below arealready configured and are ready for use, i.e.«ready to go». You only have to select a suitableseparating column (please refer to our separateleaflet) and connect to a PC or Notebook via a seri-al port. Your local Metrohm agency will be pleasedto provide you with information about the optimalsolution for your particular application and can, onrequest, supply you with a fully installed PC.

7

With the 761 Compact ICyou can experience a double quantum leap in ionchromatography: extremely compact design, really simple operation and maxi-mum performance. Analysisas it ought to be: short,quick and straight to the tar-get. This is the first upwardquantum leap: the optimalIC system for each applica-tion and each laboratory.The second quantum leap is downward: no matterwhether with or withoutsuppression, never has ionchromatography been sofavorably priced. This is good for you and also goodfor ion chromatography, as this means that IC isable to prove that it is a perfect analytical system.The quality remains unchanged: with Metrohm youare banking on fifty years’ experience in ion analysis and on quality «Made in Switzerland».

The most important features of the 761 Compact IC:• Extremely compact design – the 761 Compact IC

finds enough space on every laboratory bench• Perfect integration – injection valve, dual-piston

pump, column, Metrohm Suppressor Module,high-performance detector, peristaltic pump, dataprocessing – all combined in a very small space

• Minimum peripherals – one connection to a freeCOM interface on the PC is all that is needed

• One-button operation – the only switch you willfind is the on/off switch

• PC control – all the 761’s functions are PC-controlled

• Rapid start – click on the required application inthe menu and your IC System is ready and configured

• Analog output for connection to external data sys-tems

• Online applications – updating the applicationscan be carried out at any time by downloadingthe latest methods from the Internet, «www.metrohm.com», into the 761 Compact IC

You can choose between a system with chemicalsuppression (2.761.0020) and one without chemicalsuppression (2.761.0010). In the version 2.761.0020the Metrohm Suppressor Module «MSM», as well asthe peristaltic pump for the regeneration and rinsingsolutions, can be switched on and off by mouse-click.

The eluent and storage containers for the regenera-tion of the «MSM» can be conveniently contained inthe eluent organizer of the 761. This ensures short

tubing connections. The openings for attaching thesyringe or connecting a sample changer are locatedon the front panel of the 761. The rear panel hasthe connections for the mains cable, detector andthe RS 232C interface of your computer. You willalso find the interface for the freely configurableRemote lines of the 761 IC here and, last but notleast, the on/off switch.

For automation tasks we can recommend the 766 IC Sample Processor (Order number2.766.0010), the 788 IC Filtration Sample Processor(Order number 2.788.0010), the 788 IC DialysisSample Processor (Order number 2.788.0020) or the 813 Compact IC Autosampler (Order number2.813.0010).

Technical informationCompact high-performance ion chromatographysystem with (2.761.0020) or without (2.761.0010)chemical suppression• Built-in 6-way injection valve• Low-pulsation dual-piston pump, flow range 0.2

to 2.5 mL/min, maximum pressure 25 MPa (250bar, 3625 psi)

• Pulsation absorber• Insulated column compartment• Eluent organizer• Detector temperature-stabilized to better than

0.01 °C, temperature range 25...45 °C in 5 °C steps, three measuring ranges 0...50 µS/cm,0...250 µS/cm, 0...1000 µS/cm

• Analog output 0...1000 mV• Metrohm Suppressor Module «MSM»

(2.761.0020 only)• Built-in 22-bit A/D converter• 8 Remote output lines for controlling external

devices• Software for control and integration • Free-of-charge application updates from the

Internet• Dimensions in mm (W/H/D) 259/446/355

Ordering information2.761.0010 761 Compact IC for anion or cation

determination without chemical suppression

2.761.0020 761 Compact IC for anion determination with chemical suppression

6.1826.060**Pump tubing (orange/yellow)6.2821.120** Inline filter PEEK with 2 µm PE filter

plate6.2821.130 Spare PE filter plate 2 µm (10 pieces)6.2821.090* Suction filter, pore size 20 µm

* Already contained in the standard equipment of the 761 Compact IC (2.761.00X0)

** Already contained in the standard equipment of the 761 Compact IC (2.761.0020)

761 Compact IC


Online IC Advanced IC Systems

The 790 Personal IC • is favorably priced as regards acquisition, operation

and maintenance• allows you to assign one IC to one application• is a very attractive alternative to photometry and

gravimetry

The 790 Personal IC is completely controlled from aPC. Operation is extremely simple thanks to its user-friendly software. The conductivity detector coversconcentrations from the ppb to the percent range; its temperature stability is outstanding. The time-proven «MSM» Metrohm Suppressor Module allowsfavorably-priced analyses with chemical suppressionand is included in the version 2.790.0020 as stan-dard.

For automation of determinations with the 790Personal IC the following instruments are available:766 IC Sample Processor, 788 IC Filtration SampleProcessor and 813 Compact IC Autosampler. The eluent organizer is available as an option.

The 790 Personal IC is designed as a first-user modelor as a «stand alone» ion chromatograph for a singledefined application. The instrument is quick and easyto use. There are no compromises regarding datasecurity and accuracy of the results – these are of the highest level.

The very good price-performance ratio does notmean that you have to do without top-quality com-ponents:

• The built-in IC pump used in the 790 Personal IC is based on the time-proven serial dual-piston principle. This guarantees a very constant and low-pulsation flow and therefore a steady baseline.

• The time-proven «MSM» Metrohm SuppressorModule is used for chemical suppression; thismeans that chemical suppression and low costs are no longer contradictory terms.

• The conductivity detector, the heart of the 790Personal IC, impresses by its outstanding tempera-ture stability which enables it to provide low-noiseand precise conductivity measurements.

The conductivity detector of the 790 Personal IC hasa measuring range of 1000 µS/cm. This means thation concentrations from the high ppb to the percent-age range can be determined. The determinationlimit is about 0.1 mg/L (approx. 100 ppb) for anionsand cations. You can work with or without chemicalsuppression. As a result you can also utilize the advantages of weakly acidic eluents in anion analysiswhen working without chemical suppression.

Of course, you can also adapt the 790 Personal IC forchanging applications. However, in this case the 761

Advanced IC Systems

Compact IC or the modular IC systems offer greaterflexibility. With these instruments you can store thesystem parameters of the various applications veryconveniently with the 761 software or the IC Netsoftware and call them up again whenever neces-sary. Please contact your local Metrohm agency whowill provide you with competent advice for solvingapplication problems and help you to select theoptimal IC system for your particular requirements.

With the 790 Personal IC you will receive a top-quality ion chromatograph. The range of applica-tions for which it can be used is correspondinglylarge. Its full capabilities are demonstrated foranions and cations in the ppm range.

Technical informationCompact ion chromatography system with (version 2.790.0020) or without (version2.790.0010) chemical suppression• Built-in 6-way injection valve• Low-pulsation dual-piston pump, flow range

0.2 to 2.5 mL/min, maximum pressure 25 MPa(250 bar, 3625 psi)

• Thermally and electrically insulated column compartment

• Detector temperature-stabilized to better than0.01 °C, temperature 40 °C, measuring range0...1000 µS/cm

• «MSM» Metrohm Suppressor Module (version 2.790.0020 only)

• Built-in 22-bit A/D converter• 1 Remote output line for controlling an external

device• Control and integration software• Dimensions in mm (W/H/D) 255/385/343

Ordering information2.790.0010 790 Metrohm Personal IC without

chemical suppression2.790.0020 790 Metrohm Personal IC with

chemical suppression6.1826.060* Pump tubing (orange/yellow) 6.2821.120** Inline filter PEEK with 2 µm PE filter

plate6.2821.130 Spare PE filter plate 2 µm (10 pieces)

* Already contained in the standard equipment of the 790 Personal IC Version 0020

** Already contained in the standard equipment of the 790 Personal IC

Option6.5324.000 Eluent Organizer for optimal storage

of the eluent container and bottles for regenerating the «MSM»; includes three bottles and additionalaccessoires

6.2620.150 Pulsation Absorber

8

790 Personal IC

9

With the 792 Basic IC Metrohm is offering you two different things:In the first place we are providing the education sector with an extraordinarily favorably-priced ionchromatograph that will allow schools, universities,occupational and advanced training facilities as wellas company-internal training laboratories to pur-chase one or more ion chromatographs and equiptheir training rooms with the necessary workplaces.

In the second place Metrohm has published a practical text-book that presents the basics ofion chromatography in an easilyunderstandable way as well ascovering the theory at both a simple and at a more demandinglevel. It also describes 22 experi-ments which open up the wholeworld of ion chromatography tothe students.

With the 792 Basic IC the stu-dents are provided with an instrument with whichthey can learn the essential features of ion chro-matography in a very simple way. As ion chromatog-raphy belongs to the HPLC family this means thatthe basics of this analytical technique are also cov-ered. The software program allows different hard-ware systems to be created and operated using dif-ferent methods. Individual methods can be createdand stored for each experiment, each student andeach application.

The 792 Basic IC is, of course, not just limited toeducation but can also carry out standard applica-tions in the analytical laboratory. Regardless ofwhether anions or cations are to be analyzed, orwhether organic acids need to be determined – the 792 Basic IC provides reproducible and accurateresults within a very short time. The detection limit is below 100 ppb (0.1 mg/kg).

In all Metrohm instruments, and this includes thenew 792 Basic IC, the expression «cost of owner-ship» is of great importance. This covers the runningcosts associated with the instrument. For the BasicIC these are very low. It does not require an expen-sive external supply of gas as the built-in dual-pistonpump provides the necessary performance as a mat-ter of course. This means that the pump is responsi-ble for the low-pulsation baseline. Even the injectionvalve works without nitrogen or helium. This savesmoney. If operated properly, the working life of the«MSM» Metrohm Suppressor Module for chemicalsuppression is practically unlimited.

Carbonate/hydrogen carbonate eluent, dilute sulfuric acid and water for regenerating and rinsingthe suppressor – all the necessary solutions can beprepared at a low cost. Even with high samplethroughputs the running costs can be kept low. The software is included with the instrument anddoes not have to be ordered separately.

Technical informationCompact ion chromatography system with PC control.• Built-in 6-way injection valve• Low-pulsation dual-piston pump, flow range

0.2 to 2.5 mL/min, maximum pressure 25 MPa(250 bar, 3625 psi)

• Thermally and electrically insulated column compartment

• Detector temperature-stabilized to better than0.01 °C, temperature 40 °C, measuring range0...1000 µS/cm

• «MSM» Metrohm Suppressor Module for the determination of anions with chemical suppression

• Built-in 22-bit A/D converter• Control and integration software• Textbook• Dimensions in mm (W/H/D) 255/385/343

Ordering information2.792.0020 792 Metrohm Basic IC for anion

determination with or without chemical suppression and cation determination without chemical suppression. Particularly suitable for education; comprehensive practical IC text book included.

6.1826.060*Pump tubing (orange/yellow) 6.2821.120*Inline filter PEEK with 2 µm PE filter


* already included in the standard equipment of the 792 Basic IC

Option6.5324.000 Eluent Organizer for optimal storage

of the eluent container and bottles for regenerating the «MSM»; including three bottles and additionalaccessories

6.5325.000 Basic IC Starter Kit, consisting of Metrosep Anion Column Dual 1 (150 mm) with holder as well as Pulsation Absorber

792 Basic IC



761 Compact IC 790 Personal IC Basic IC 792

Software for control andintegration included Yes Yes Yes

Use of IC Net software Yes No No

Number of IC per PC unlimited with IC Net; 2 11 without IC Net

Measuring ranges 1000/250/50 µS/cm 1000 µS/cm 1000 µS/cm

Pulsation dampener Yes Option Option

Stability of detector temperature < 0.01 °C < 0.01 °C < 0.01 °C

Low-pulsation dual-piston pump Yes Yes Yes

Maximum pressure 25 MPa 25 MPa 25 MPa(250 bar, 3625 psi) (250 bar, 3625 psi) (250 bar, 3625 psi)

Flow rate 0.2…2.5 mL/min 0.2…2.5 mL/min 0.2…2.5 mL/min

Metrohm Suppressor Module (MSM) incl. with or w/o with or w/o included in thetwo-channel peristaltic pump selectable selectable delivery package

Built-in 22-bit AD converter Yes Yes Yes

Remote I/O lines (output) 8 1 0

Automation Yes Yes No

Preprogrammed system files Yes Yes Yes

Storage of system and method files Yes No Yes

Frequent method change possible Yes not recommended Yes

Queue (sample table) Yes Yes No

Built-in leak sensor Yes No No

Eluent organizer Yes Option Option

Updating the applications via Internet Yes No No

IC training manual Option Option Yes

Metrohm Compact IC – important differences at a glance

Advanced IC Systems

10

11

«Top of the line» ion chromatography

Precise analysis – from ppm to ppt, from milligram to nanogram per liter. The built-in column heatinglowers the detection limits even further. The opti-mized high-pressure pump reduces pulsation to theabsolute minimum. Improved signal lines guaranteean even lower sensitivity to interference.

Flexible analysis that can be individually and rapidlyadapted to suit each application. The Metrohm IinlineSample Preparation «MISP» technique (see page 14)significantly simplifies work and improves the preci-sion of the results.

Simple analysis that can be reliably controlled byanybody. The new user interface IC Cap is child’splay to use. Operator errors are reliably avoided. The dialog can be carried out in several languages.

Favorably-priced analysis – low maintenance costs,simple service, no external gas supply, no trouble-prone cation suppressor and 10 years’ warranty onthe «MSM» anion suppressor.

In a class of its own: the new Advanced IC

«MIC-1 Advanced» – Modular anion or cation system with electronic suppression

Advanced IC Systems

The «MIC-1 Advanced» IC system has three compo-nents: the low-pulsation 818 Dual-Piston Pump, the819 High-Performance Detector and the 820 ICSeparation Center. Both anions and cations can bedetermined with this arrangement without chemicalsuppression. This high performance system is veryfavorably priced.

The special electronic suppression of the 819 ICDetector covers very low concentration ranges (<10 ppb) for cations and anions. The built-in col-umn oven and the extremely low-pulsation IC pumpadditionally improve the signal-noise ratio.

As work is carried out without chemical suppressionthis means that the range of eluents that can beused is practically unlimited. Difficult separating problems can be solved any limitations imposed bythe eluent system or chemical suppressor into con-sideration.

The system can be automated with the 813Compact Autosampler (Order number 2.813.0010),the 766 IC Sample Processor (Order number2.766.0010) or the 788 IC Filtration SampleProcessor (Order number 2.788.0010).

Ordering information «MIC-1 Advanced»2.818.0110 818 IC Pump2.819.0010 819 IC Detector (metal)2.820.0210 820 IC Separation Center

(1 injector, column heating)2.830.0020 830 IC Interface 6.2620.150 Pulsation Absorber



The «MIC-2 Advanced» modular anion system withelectronic and chemical suppression gives you thelargest possible degree of flexibility: you have a freechoice of eluents whenever you are working withelectronic suppression alone. As the sensitivity of thesystem can be increased by using chemical suppres-sion for anions (in contrast to cations), this systemadditionally contains the «MSM» Metrohm Suppres-sor Module, which is incorporated in the 820 ICSeparation Center. The 833 IC Liquid HandlingPump Unit is used for regeneration and rinsing. The 820 Separation Center is equipped with a col-umn oven which lowers the detection limits evenfurther, particularly when working with a high background conductivity.

It goes without saying that cations can also bedetermined with this system. In this case the suppressor and pump unit are simply switched off.After the column and eluent have been changed the cation system is ready for use.

The system is completely made from PEEK: pumphead, valve, pulsation absorber, «MSM» and all inline filters are made from PEEK (polyetheretherke-tone). The maximum pressure at which such a system can be operated is 35 MPa (5076 psi).

Simple automation with the 766 IC Sample Proces-sor (Order number 2.766.0010) or the 788 IC Filtra-tion Sample Processor (Order number 2.788.0010)can be carried out directly and without additionalcables. If the 833 IC Liquid Handling Pump Unit isalso to be remotely controlled by the sample chang-er then a cable and an adapter are additionallyrequired:

6.2125.090 Remote extension cable (1:1)6.2125.120 Adapter for distributing Remote lines

to five 25-pin sockets

Ordering information «MIC-2 Advanced»2.818.0110 818 IC Pump2.819.0110 819 IC Detector (PEEK)2.820.0230 820 IC Separation Center

(1 injector, «MSM», column heating)2.830.0020 830 IC Interface 2.833.0010 833 IC Liquid Handling Pump Unit 6.2620.150 Pulsation Absorber

«MIC-2 Advanced» – Modular anion systemwith chemical suppression

Advanced IC Systems

12

13

«MIC-3 Advanced» – Modular anion andcation system with chemical suppression

For automation with the 766 IC Sample Processor(Order number 2.766.0010) or the 788 IC FiltrationSample Processor (Order number 2.788.0010) thefollowing items are required:

6.2125.090 Remote extension cable (1:1)6.2125.120 Adapter for distributing Remote lines

to five 25-pin sockets6.2141.120 Cable 766–818–819 (2)6.2134.090 RS 232C for sample changer –

830 Interface

Ordering information «MIC-3 Advanced» 2 x 2.818.0110 2 x 818 IC Pump2.819.0010 819 IC Detector (metal)2.819.0110 819 IC Detector (PEEK)2.820.0220 820 IC Separation Center

(2 injectors, column heating)2.830.0020 830 IC Interface 2.833.0020 833 IC Liquid Handling

Suppressor Unit 2 x 6.2620.150 2 x Pulsation Absorber

Determination of cations with electronic suppres-sion? Determination of anions with electronic andchemical suppression? Making parallel and inde-pendent measurements? This is no problem with the combined Metrohm «MIC-3 Advanced» anion-cation IC system. Two completely separated chan-nels, which on request can be controlled simultane-ously or independently by software, allow optimalwork at the highest performance level.

The outstanding abilities of this system – high signal-noise ratio, auto-zero function, range andfull-scale adaptations, low-pulsation pump system,etc. – allow sample preparation to be dispensedwith wherever a preconcentration technique wouldotherwise have to be used. This simplifies andaccelerates your work and also helps to reducecosts.

Suppression only when it is necessary – for thedetermination of anions. The «MSM» is resistant to pressure and also resistant to a wide range of solvents. Even sulfuric acid at a concentration of 2 mol/L does not affect it. This means a long working life and low maintenance costs.



Integrated into the Separation Center of the new Advanced ICSystems is an electronically controlled column heating device.The heating element has room for two columns.

Crystal clear, clinically pure, no bacteria and no par-ticles: this would be the ideal sample for ion chro-matography. Unfortunately in reality this is often notthe case. Apart from the ions to be analyzed, thesamples also may contain large amounts of aggressivesubstances which, if the sample were to be measureddirectly, would make the analysis difficult if not im-possible. Strongly contaminated samples could des-troy the column or block capillaries, pump valves orthe detector.

This is why critical samples must principally be subjected to a sample preparation procedure. This in-cludes all the steps which a sample must passthrough before it is introduced into the IC system.

In practice a number of methods are used: filtration,ultrafiltration, solid-phase extraction, dialysis, dilution,preconcentration, etc. One thing common to all these methods is that they usually need to be carriedout manually. However, manual sample preparationmeans a high workload is required; this is often accompanied by poorer reproducibility, inexact results and high costs.

The solution is MISP

Metrohm can now provide you with «MISP»,Metrohm Inline Sample Preparation, a range of methods which allows sample preparation to be automated and carried out considerably more efficiently than was previously the case.

«MISP» has an enormous potential for the optimi-zation of sample preparation in ion chromatography.Costs can be dramatically reduced, the quality of theresults is increased significantly and the field in whichion chromatography can be used as a powerful ana-lytical method is considerably expanded.

What is the principle behind Metrohm Inline SamplePreparation? In the course of the analysis there is onesmall but crucial alteration. Whereas sample prepara-tion steps were previously carried out before the sam-ple was placed on the sample changer or introducedinto the IC system, these sample preparation stepshave now been automated and included between the sample changer and the IC system. The list belowprovides an overview of the various fully automatedsteps that can be carried out inline between the sample vessel and injection valve.

• Metrohm Inline UltrafiltrationMetrohm 788 IC Filtration Sample Processor (page 48), Metrohm 833 IC Liquid Handling Ultrafiltration Unit (page 37)

• Metrohm Inline Dialysis«MIC-7 Compact» (page 19), «MIC-7 Advanced»(page 18)

• Metrohm Inline Matrix Elimination«MIC-6 Advanced» (page 17)

• Metrohm Inline Neutralization«MIC-6 Advanced» plus Metrohm 833 Liquid Handling Sample Preparation Unit (page 17)

• Metrohm Inline Cation Removal«MIC-5 Advanced» plus Metrohm 833 Liquid Handling Sample Preparation Unit (page 16)

• Metrohm Inline Transition Metal Removal«MIC-5 Advanced» plus Metrohm 833 Liquid Handling Sample Preparation Unit (page 16)

• Metrohm Inline Preconcentration«MIC-4 Advanced» (page 15), «MIC-5 Advanced» (page 16)

• Metrohm Inline Calibration«MIC-6 Advanced» (page 17), Online IC 811 (page 23)

• Metrohm Inline Spiking«MIC-6 Advanced» (page 17), Online IC 811 (page 23)

Further details can be found in our leaflet«Metrohm Inline Sample Preparation – Methods,Sample Changers, Systems», which you can obtainfree of charge from your local Metrohm agency.

Metrohm Inline Sample Preparation «MISP»

Advanced IC Systems

14

15


Online IC

Ordering information «MIC-4 Advanced»2.818.0110 818 IC Pump 2.819.0010 819 IC Detector (metal)2.820.0210 820 IC Separation Center

(1 injector, column heating)2.830.0020 830 IC Interface 2.766.0010 766 IC Sample Processor 6.2620.150 Pulsation Absorber

«MIC-4 Advanced» – Modular cation systemwith electronic suppression and sample preconcentration

The modular «MIC-4 Advanced» anion or cationsystem with electronic suppression and preconcen-tration has, when compared with a simple anion-cation system consisting of an 818 IC Pump, 819 ICDetector and 820 IC Separation Center, beenextended by two further components: the 766 ICSample Processor and a preconcentration columnwhich is located on the injection valve instead of thesample loop.

The built-in peristaltic pump of the 766 IC SampleProcessor transfers your standard and then yoursamples to the preconcentration column. The pre-concentrated sample is then eluted onto the separa-ting column in counterflow.

The favorably-priced system works with electronicsuppression. This is characterized by the fact thatthe peak area or height is directly proportional tothe concentration of the particular ion throughout awide range. This is why it is normally only necessaryto carry out a one-point calibration, which makeswork quicker and easier.

Advanced IC Systems

The «MIC-5 Advanced» modular anion system withchemical suppression and sample preconcentrationopens up numerous possibilities for detection at lowand very low concentrations. Even the detection ofanions in concentrations in the lower ppt range isachieved easily and reliably.

The 766 IC Sample Processor allows the system tobe automated to a large extent. As chemical sup-pression is used, multi-point calibrations are usuallyrequired. With the 766 IC Sample Processor this can be carried out automatically and reproducibly.

The system can be converted from an anion systemwith preconcentration and chemical suppression toa fully automated cation system with electronic sup-pression with and without sample preconcentrationin only a few moves.

Its universal use extends the range of applications.Once again the modular design and flexibility of the Metrohm Advanced IC Systems pays for itself.

Ordering information «MIC-5 Advanced» 2.818.0110 818 IC Pump 2.819.0110 819 IC Detector (PEEK)2.820.0230 820 IC Separation Center

(1 injector, «MSM», column heating)2.830.0020 830 IC Interface 2.833.0010 833 IC Liquid Handling Pump Unit 2.766.0010 766 IC Sample Processor 6.2620.150 Pulsation Absorber

«MIC-5 Advanced» – Modular anion systemwith chemical suppression and sample preconcentration

Advanced IC Systems

16

Modulare IC-Systeme

17

Usually it is not the analysis itself that causes prob-lems, but rather the sample matrix in which theanalysis is to be carried out. The «MIC-6 Advanced»modular anion system with chemical suppression,sample preconcentration and matrix eliminationsimplifies sample preparation in two respects: on theone hand matrix effects can be eliminated, while onthe other hand the preconcentration technique canbe used to reliably determine low concentrations.

The «contaminated» sample is transferred to the«sample loop» of valve B by the built-in peristalticpump of the 788 IC Filtration Sample Processor. The valve is switched and now uses deionized water,supplied via the 833 IC Liquid Handling Pump Unit,to transfer the sample to the preconcentration column located on valve A of the 820 IC SeparationCenter. At the same time the deionized water isused to rinse the contaminants from the preconcen-tration column. These steps can be repeated asoften as necessary. When the enriched sample vol-ume is large enough, valve A is switched and thesample is transferred to the separating column –now without the interfering matrix.

Matrix elimination significantly increases the workinglife of the anion and cation columns. Sample pre-concentration extends the range of applications.Automation reduces the costs per sample. WithMetrohm Advanced IC Systems you can safely meetall the demands placed on you.

«MIC-6 Advanced» – Modular anion systemwith chemical suppression, sample preconcentration and matrix elimination


Online IC

Ordering information «MIC-6 Advanced» 2.818.0110 818 IC Pump2.819.0110 819 IC Detector (PEEK)2.820.0220 820 IC Separation Center

(2 injectors, column heating)2.830.0020 830 IC Interface 2.833.0010 833 IC Liquid Handling Pump Unit 2.833.0020 833 IC Liquid Handling Suppressor

Unit2.788.0010 788 IC Filtration Sample Processor 6.2620.150 Pulsation Absorber6.2125.090 Remote extension cable (1:1)6.2125.120 Adapter for distributing Remote lines

to five 25-pin sockets

Advanced IC Systems

Advanced IC Systems

18

«MIC-7 Advanced» – Modular anion systemwith chemical suppression and dialysis

rest. The acceptor solution is then transferred to the sample loop of the 820 IC Separation Centerand the sample is analyzed in the normal manner.

High reproducibility, long membrane life, dialysisrates >98% and very low detection levels for anionsand cations make the Metrohm Advanced IC DialysisSystem into a powerful tool for overcoming difficultapplication problems.

Ordering information «MIC-7 Advanced» 2.818.0110 818 IC Pump2.819.0110 819 IC Detecor (PEEK)2.820.0220 820 IC Separation Center

(2 injectors, column heating)2.830.0020 830 IC Interface 2.833.0020 833 IC Liquid Handling Suppressor

Unit2.788.0020 788 IC Dialysis Sample Processor 6.2620.150 Pulsation Absorber6.2125.090 Remote extension cable (1:1)6.2125.120 Adapter for distributing Remote lines

to five 25-pin sockets6.2714.010*Dialysis membrane, cellulose acetate;

50 pieces

* Already contained in the standard equipment of the 788 IC Dialysis Sample Processor (2.788.0020)

Automated sample preparation is increasingly becoming an integral part of a high-performance IC system. With the introduction of the patenteddialysis method Metrohm has placed a new mile-stone on the way towards this goal.

The determination of anions and cations in fruitjuice, milk, soil eluates or boring oil emulsions canbe carried out quickly and without any problemswith the Metrohm «MIC-7 Advanced» dialysis sys-tem and without damaging the separating column.

Dialysis is neither filtration, nor extraction, nor digestion – see page 35. In dialysis the ions passfrom the sample solution into the acceptor solutionby diffusion through a dialysis membrane. After only a short time a concentration equilibrium isestablished between the sample solution and theacceptor solution. The number of ions between the sample solution is not reduced as they are constant-ly being resupplied. While the ions can pass throughthe membrane almost unhindered, larger particles – the matrix – are simple transported past the dialysismembrane. This reduces matrix effects to the absolute minimum.

The Metrohm dialysis method works according tothe patented stopped-flow principle: about 10 mLsample is passed along the dialysis membrane by theperistaltic pump built into the 788 IC Dialysis SampleProcessor while the acceptor solution remains at

Modulare IC-Systeme

19

The compact IC system with integrated dialysis. Forroutine tasks and detection limits down to the ppbrange, the combination of the 761 Compact IC withthe 788 IC Dialysis Sample Processor is the optimalsolution whenever contaminated samples have to bemeasured.

Dialysis is the method of choice whenever particles,oil droplets or coarse organic contaminants have tobe kept away from the whole IC system. The cellu-lose acetate dialysis membrane provides the neces-sary security without limiting the reproducibility and precision of the measurements.

As two valves are required for the dialysis, the 761Compact IC is extended by one valve with the 812Valve Unit. The system is controlled by the IC Netsoftware. This version requires two free COM portson the PC.

Ordering information «MIC-7 Compact» 2.761.0020 761 Compact IC «MSM»2.788.0020 788 IC Dialysis Sample Processor 2.812.0010 812 Valve Unit – 1 metal-free 6-way

valve6.2125.110 Cable RS 232C – PC (DB25/9)6.2714.010*Dialysis membrane, cellulose acetate;

50 pieces

* Already contained in the standard equipment of the 788 IC Dialysis Sample Processor (2.788.0020)

«MIC-7 Compact» – Compact anion systemwith chemical suppression and dialysis

Advanced IC Systems


Online IC

Advanced IC Systems

20

The «MIC-8 Advanced» modular IC system consistsof the 817 Bioscan, 818 IC Pump and 812 ValveUnit for sample injection. Data acquisition and A/Dconverter are already included in the 817 Bioscan,so that no additional data acquisition module is nec-essary.

The 817 Bioscan extends the modular ion chro-matography system from Metrohm by includingcarbohydrate analysis in the range of IC applica-tions. The heart of the 817 Bioscan is the pulsedamperometric detector with built-in column oven.Control and data acquisition are via the MetrodataIC Net software.

The 817 Bioscan analyzes• sugars• alcohols• sugar alcohols• sugar acids• oxidizable or reducible substances

Two free RS 232C COM ports are required at the PCor Notebook. The system can be automated with allMetrohm sample changers (813, 766, 788).

«MIC-8 Advanced» – Modular system with 817 Bioscan for sugar analysis

Ordering information «MIC-8 Advanced»2.818.0110 818 IC Pump 2.817.0010 817 Bioscan 2.812.0010 812 Valve Unit – 1 metal-free 6-way

injection valve6.2125.110 RS 232C cable for connecting

818 IC Pump – PC (DB25w/9w)

Technical informationCompact chromatography and detector module for amperometric detection• Three-electrode measuring cell with gold

working electrode • Pulsed amperometric detection (pulse mode)• Amperometric detection with constant working

potential (DC mode)• Cyclic voltammetry (scan mode)• Potential range: -2.00...+2.00 V• Built-in A/D converter• Temperature range of column oven: 5 °C above

room temperature to 60 °C; temperature stability ±0.1 °C

• IC Net software included

Ordering information «MIC-9 Advanced»2 x 2.818.0110 2 x 818 IC Pump 2.819.0110 819 IC Detector (PEEK)2.820.0220 820 IC Separation Center

(2 injectors, column heating)2.817.0010 817 Bioscan2.830.0020 830 IC Interface2.833.0020 833 IC Liquid Handling

Suppressor Unit2.788.0010 788 IC Filtration Sample Processor2 x 6.2620.150 2 x Pulsation Absorber6.2125.090 Remote extension cable (1:1)6.2125.120 Adapter for distributing Remote

lines to five 25-pin sockets6.2134.090 Cable 830 IC Interface –

817 Bioscan

Modulare IC-Systeme

21

The «MIC-9 Advanced» IC system combines the twomost important electrochemical detection methods:conductivity measurement and amperometric deter-mination. Conductometry with the 819 High-Per-formance Detector analyzes either cations with elec-tronic suppression or anions with chemical suppres-sion down to the lower ppb range. The pulsed am-perometric detector of the 817 Bioscan determinesreadily oxidizable or reducible substances, primarilythe carbohydrates. The detection sensitivities areequal to those of the conductivity detector. The 817Bioscan can be operated in three different modes:pulsed amperometric, amperometric or in the scanmode. The latter mode is chiefly important in thedevelopment of applications and is used to deter-mine the optimal oxidation potential.

With the «MIC-9 Advanced» you will receive a com-pletely flexible system, with which you can workwith two channels, either in parallel or independent-ly. The only common system component is the 788IC Filtration Sample Processor which, thanks to itsultrafiltration cell, is outstandingly suitable for sam-ple preparation.

«MIC-9 Advanced» Combined modular system for anion and sugar analysis



The Metrohm high-pressure gradient system allowsthe separation of anions which elute very quicklyand anions which elute extremely slowly in a singlerun. The gradient technique, regardless of whether a carbonate or hydroxide eluent is used, offers enor-mous advantages for this type of application andprovides a better separation with significant savingsin time.

The system makes it possible to work with very concentrated eluents. The 828 IC Dual Suppressor isable to chemically suppress eluents up to a concen-tration of 50 mmol/L HCO3

– or OH– at a flow of 1 mL/min. Regeneration takes place continuously byelectrochemical means, so that additional solutionsare no longer required.

The 828 IC Dual Suppressor is also equipped with a system for CO2 suppression that reduces the back-ground conductivity to a few µS/cm. The injectionpeak and system peak disappear almost completely,the baseline remains virtually constant even withincreasing eluent concentrations.

The gradient system can be extended at any time toform a quaternary high-pressure gradient system.

«MIC-10 Advanced» Binary high-pressure gradient system for the determination ofanions with chemical suppression

Ordering information «MIC-10 Advanced»2 x 2.818.0110 2 x 818 IC Pump2.819.0110 819 IC Detector2.820.0210 820 IC Separation Center

(1 injector, column heating)2.830.0020 830 IC Interface2.828.0010 828 IC Dual Suppressor6.2758.000 Gradient mixing spiral6.2620.150 Pulsation Absorber

Advanced IC Systems

22

The 811 Online IC from Metrohm provides optimal,industry-compliant IC analyses. It is characterized byits easy operation, good reliability even under roughoperating conditions, minimal external supply re-quirements, high degree of data security and, ofcourse, precise and reproducible results. The instru-ment profits from Metrohm’s years of experience inonline analysis.

The 811 Online IC can be adapted to suit virtuallyany application. The single-channel instrument canbe used to determine either cations or anions; thetwo-channel version is destined to determine cationsand anions simultaneously. The sample sequence isfreely programmable. In each of the 10 individualsample flows a number of ion types can be deter-mined and monitored. Control cards show the userat a glance whether the determined concentrationsare in accordance with the set values.

The IC system of the 811 Online IC uses first-classcomponents which have proved themselves in themodular Metrohm IC systems. The complete instru-ment can be remotely controlled and is designed so that it can also be used by non-chemists.

The 811 Online IC sets new standards in online analysis regarding its price-performance ratio, user friendliness, reliability and the quality of the analytical results.

Technical information• Online ion chromatography system with one or

two channels• 10 sample flows• Flexible, can be adapted to suit virtually any IC

application• Dual-piston IC pump guarantees low

pulsation• «MSM» Metrohm Suppressor Module for

chemical suppression• Conductivity detector with excellent temperature

stability – better than 0.01 °C – and perfect electrical shielding thanks to Faraday cage

• Two or four 6-way valves are built in• Low-noise signal for highest sensitivity• Eluent degasser is built in• No external gases required• Battery-supported power failure backup means

that power cuts of up to 30 min do not affectoperation

• Modem and remote control software• Housing dimensions in mm (W/H/D):

920/1860/642 (casters and projecting parts nottaken into account)

• Weight approx. 450 kg

811 Online IC Process Analyzer

Ordering information 811 Online IC2.811.0014 Flexible ion chromatography system

for 230 V power supply, 1-channel version, with built-in IC pump, 10-way sampling valve and two 6-way injection valves

2.811.0015 As 2.811.0014, but for 115 V power supply

2.811.0024 Flexible ion chromatography system for 230 V power supply, 2-channel version, with two built-in IC pumps, two 10-way sampling valves and four 6-way injection valves

2.811.0025 As 2.811.0024, but for 115 V power supply

23


Online IC Online IC Systems

Online IC Systems

24

The 821 Compact Online IC extends the range ofMetrohm industry-compliant online ion chro-matographs. Up to 10 different sample flows can befreely selected for analysis. The design of the 821Online IC allows the reliable analysis of anions withand without suppression and cations down to thelower ppb range. Simple operation, high degree ofdata security, good autonomy and precise results areguaranteed even under very critical surroundingconditions, e.g. in production or machine halls.

The Metrohm online concept allows previouslyunthought-of availability (up times) to be achievedtogether with very low running costs. If mainte-nance work should ever be necessary – the softwarewill inform you – then this can be carried out quicklyand, above all, easily.

The 821 Online IC is available as a single-channelversion. It includes an industrial PC, interruption-freepower supply with up to approx. 45 min autonomy,modem for remote maintenance, software with control cards for measuring results, calibrations andperformance checks as well as for controlling theanalysis and the 10-way sample selection valve. Theinstrument is supplied mounted on a mobile rack. It is additionally prepared for wall mounting.

Technical information• Conductivity detector in Faraday cage,

temperature stability better than ±0.01 °C• Extremely low-pulsation, serial dual-piston pump• No external gas supply required• Anion determination with or without suppression• Detection limits for anions/cations <20 ppb/

<50 ppb• 10 sample flows• 10-way sample selection valve• 2-channel peristaltic pump for regenerating and

rinsing the suppressor• 2-channel peristaltic pump for sample solution or

standard• UPS support battery for up to 45 min operation

during power cut• Modem and remote control software• Housing dimensions in mm (W/H/D):

650/1860/642 (casters and projecting parts nottaken into account)

• Weight approx. 240 kg

821 Compact Online IC Process Analyzer

Ordering information Compact Online IC 8212.821.0014 Compact Online IC (1-channel),

230 V, for anions or cations2.821.0015 Compact Online IC (1-channel),

115 V, for anions or cations

25


Online IC IC Modules – Detectors

Technical informationHigh-performance conductivity detector• Detector block

temperature 25...45 °C in 5 °C steps• Temperature stability <0.01 °C• Cell constant calibrated, can be

set from 13...21 cm–1

• Cell volume 0.8 µL (nominal)• Measuring ranges 7 ranges from

0...100 µS/cm to 0...10 000 µS/cm

• Full-scale ranges 11 steps from 0.05...100% of the measuring range

• Measured value output 0...1 V analog• Auto zero yes, manual or

triggered externally• Remote lines 8 I/O for TTL or

relays• Dimensions

in mm (W/H/D) 255/130/343

819 Advanced IC Detector

Ordering information2.819.0010 819 IC Detector (metal)2.819.0110 819 IC Detector (PEEK)

The 819 IC Detector is the top-class conductivitydetector. It has been developed specially for ionchromatography with and without chemical suppression. It is able to reliably determine even very small signals against a very high background conductivity – up to 10 000 µS/cm. The 819 IC Detector is an integral part of the modularAdvanced Metrohm IC systems. The wet chemistrypart and the electronics are strictly separated.

The detector block with built-in measuring cell isthermally and electrically shielded against outsideinfluences. All signal lines – including those to theA/D converter – are specially shielded. A Faradaycage reliably prevents interference by electrosmog.The measuring cell is thermostatted and is charac-terized by its temperature stability of <0.01 °C. The temperature of the detector block can be setbetween 25 °C and 45 °C. Together with electronicpreamplification in the detector block, the 819 ICDetector offers the highest degree of sensitivity atan optimal signal-noise ratio. The measuring cell ismade from stainless steel; all supply lines are eitherof PEEK (version 0110) or stainless steel (version0010).

The electronic part of the detector processes the signal up to the analog output. Seven measuringranges are available. The full-scale range can be set in 11 steps between 0.05% and 100% of the measuring range, i.e. from measuring range/2000 to measuring range/1. In combination with theauto-zero function noise is reduced to an absoluteminimum (electronic noise <0.0003% of the select-ed measuring range).

The 819 IC Detector is remotely controlled by theMetrodata IC Net or IC Cap software. Application-oriented time programs and (remote-)control programs for the whole IC system and further peripheral devices form integral parts of the 819 ICDetector. If the detector is to be controlled directlyfrom a PC without the 830 IC Interface, then the6.2125.110 cable is required for the connection 819 IC Detector – PC (25/9).

IC Modules – Detectors

26

The Metrohm 819 IC Detector offers you three pow-erful electronic possibilities of achieving an optimal signal-noise ratio. The measuring range isdetermined with «Range». If, for example, cationsare to be measured without chemical suppressionthen «Range» should be set to 0...1000 µS/cm. The «Auto Zero» function subtracts the backgroundconductivity and sets it electronically to 0 µS/cm. In addition, a special electronic noise suppressionfunction is activated. In order to record the meas-ured signal optimally, you now have the possibility of adapting «Full Scale» to your measuring signal. For example, you can set a «Full Scale» of 10 µS/cmeven though this signal is recorded against a back-ground of 600 µS/cm!

All functions can be called up or terminated at anytime during a chromatogram. The time program of the 819 IC Detector offers the greatest possibledegree of flexibility (see Application Note C-32).

[Range 1000 µS/cm]

Full Scale 1000 µS/cm, Auto Zero off: noise 45 nS/cm

Full Scale 1000 µS/cm, Auto Zero on: noise 22 nS/cm

Full Scale 10 µS/cm, Auto Zero on: noise 2 nS/cm

Noise

50 nS/cm

IC-Module –Detektoren

27

Electrochemical (amperometric) detection with the791 IC-VA Detector is an extremely sensitive detec-tion method that is used successfully in both HPLCand ion chromatography. This method is also characterized by its very high selectivity: only easilyoxidizable or reducible substances are detected –chloride or sulfate are not detected and do notinterfere with the electrochemical determination,even when present at high concentrations.

The detector can be used in series or in parallel withother detectors which are normally used in IC orHPLC (e.g. conductivity or UV/VIS detectors).

Practical IC applications:• Azide• Nitrite• Chlorite• Sulfide• Iodide• Halogens• Thiocyanate• Thiosulfate• Cyanide

Practical HPLC applications: • Phenol• Aniline• Indole• Phenothiazine• Mercaptan• Vitamin C• Vitamin A • Carotene• Purine• L-Noradrenalin• L-Adrenalin• L-Dopa• Dopamine-HCl

Numerous electrodes suitable for each amperometricapplication are available.

Technical information• Measuring technique DC amperometry• Polarization potential

range -1990...0...+1990 mVresolution 10 mVvariation ±1.5%

• Current measurement direct, non-integrating• Current measuring range 0.1 nA...10 000 µA• Time constants approx. 5.0 s for

0.1 nAapprox. 0.1 s for 5 nA

• Dimensionsin mm (B/H/D) 260/129/336

Ordering information2.791.0020 791 IC-VA Detector with detector

cell, without working electrode, for use in Advanced IC system.

Optional accessories6.0727.000* Ag/AgCl Mini-reference electrode6.1204.100** «Ultra Trace» graphite electrode tip6.1204.120** Pt electrode tip 6.1204.130** Ag electrode tip6.1204.140** Au electrode tip 6.0805.010 Mini glassy carbon electrode6.0807.000 Mini carbon paste electrode6.2801.020 Carbon paste for 6.0807.0006.2826.000 Filling tool for 6.0807.0006.2802.000 Polishing set (Al2O3)

* Already contained in the standard equipment of the 791 VA Detector

** requires contact pin M3/2 (6.2103.110)

791 IC-VA Detector


Online IC IC Modules – Detectors

The 817 Bioscan extends the modular ion chroma-tography system from Metrohm by including carbo-hydrate analysis in the range of IC applications. Theheart of the 817 Bioscan is the pulsed amperometricdetector with built-in column oven. Control anddata acquisition are via the Metrodata IC Net soft-ware. As the A/D conversion takes place in the 817Bioscan, this means that no additional interface isnecessary.

In the modular IC system any modules can be com-bined with one another. This means that it is possi-ble to operate a stand-alone system with the pulsedamperometric detector 817 Bioscan; however, it canalso be incorporated in a standard IC system for thedetermination of anions and cations without anyproblems.

The expression «sugar analyzer» is actually too narrow as, apart from carbohydrates, the 817 Bio-scan can also be used to determine alcohols, sugaralcohols, sugar acids, polysaccharides and other oxidizable or reducible substances. The new Metro-sep Carb 1 separating columns play an importantrole here. They are particularly suitable for the deter-mination of carbohydrates using alkaline eluents andpulsed amperometric detection. They are very stableunder alkaline conditions and convinces with its out-standing separating properties.

817 Bioscan

The measuring cell of the 817 Bioscan and the insu-lated column oven form a single unit which is opti-mally protected against environmental influences.The three-electrode measuring principle is applied; a gold working electrode is used as standard.

Depending on the requirements, the detector can beoperated in the DC, scan or pulse mode. The pulsemode, in which three different working potentialsare applied in sequence, is used for the determina-tion of carbohydrates.

Technical informationCompact chromatography and detector module for amperometric detection• Three-electrode measuring cell with gold

working electrode • Pulsed amperometric detection (pulse mode)• Amperometric detection at constant working

potential (DC mode)• Cyclic voltammetry (scan mode)• Potential range: -2.00...+2.00 V• Maintenance-free solid state reference electrode• Built-in A/D converter• Column oven temperature range: 5 °C above

room temperature to 60 °C; temperature stability ±0.1 °C

• Dimensions in mm (W/H/D) 255/385/343

Ordering information2.817.0010 Metrohm 817 Bioscan for pulsed

amperometric detection6.1013.000 Metrosep Carb 1 – 250 column6.1013.010 Metrosep Carb 1 – 150 column6.1013.020 Metrosep Carb 1 Guard column

IC Modules – Detectors

28

IC-Module – Pumpen

29

IC Modules – Pumps


Online IC

818 Advanced IC Pump

Technical informationFlow rate 0.1...5 mL/minMax. pressure 35 MPa (5000 psi)Dimensions in mm (W/H/D) 255/130/381

Ordering information2.818.0110 818 IC Pump (PEEK)

The 818 IC Pump has been specially optimized forion chromatography. The electronic controls of thislatest generation of high-pressure pumps have beencompletely reworked. The result: minimum residualpulsation with increased precision and flow stability.

The compact and space-saving pump unit is com-patible with the Metrohm Advanced IC System andmany other HPLC and IC systems. Up to four pumpscan be combined to form a quaternary high-pressure gradient system.

The serial dual-piston pump with two valves guaran-tees top performance. The pressure is measured veryprecisely by piezoelectric means. Starting up thepump (priming) takes place reliably and quickly.Particular attention has been given to realizing longservice intervals. It is possible to enter upper andlower pressure limits in order to ensure the greatestdegree of safety for pressure-sensitive columns. The 818 IC Pump is completely remote-controlled bythe Metrodata IC Net software, in which all systemparameters can be defined simply and clearly.

If the pump is to be controlled directly from the PC without using the 830 IC Interface then the6.2125.110 cable is required for the connection 818 IC Pump – PC (DB25w/9w).

IC Modules – Pumps

30

Technical informationChannels 2Speed of rotation 20/24 min–1 (50/60 Hz)Remote control via Remote interfaceMaximum pressure 0.4 MPaDimensionsin mm (W/H/D) 260/129/366

Ordering information2.833.0010 833 IC Liquid Handling Pump Unit6.1826.050*Pump tubing (white, yellow)6.1826.060 Pump tubing (orange, yellow)6.2821.120*Inline filter PEEK with 2 µm PE filter


* Already included in the standard equipment of the 833 IC Liquid Handling Pump Unit (2.833.0010)

833 Advanced IC Liquid Handling Pump Unit

The 833 IC Liquid Handling Pump Unit can be usedtogether with the «MSM» Metrohm SuppressorModule as well as for sample preparation and sample injection in ion chromatography and HPLC.

If the 833 IC Liquid Handling Pump Unit is usedtogether with the «MSM» which is, for example,built into the 820 Separation Center, then one chan-nel supplies sulfuric acid for regeneration while thesecond channel of the powerful peristaltic pumptransports water for rinsing the «MSM».

The 833 IC Liquid Handling Pump Unit is controlledvia the Metrodata IC Net software.

31

The mature concept of the «MSM» allows the useof organic solvent fractions in eluents – the «MSM»is 100% solvent compatible – in order to optimizethe separation or to prevent bacterial growth in theeluent.

The 833 IC Liquid Handling Suppressor Unit is con-trolled by the Metrodata IC Net software.

Technical informationSuppressorType micro packed bed

suppressorConstruction 3 cartridges in one rotorRegeneration 50 mmol/L H2SO4

(standard)Rinsing deionized water

(standard)Remote control via Remote interfaceCapacity approx. 2 h per cartridge

(with standard eluents for Metrosep Anion Dual 1 + 2)

Pressure stability 2 MPa without interrupting the analysis

PumpChannels 2Speed of rotation 20/24 min–1 (50/60 Hz)Maximum pressure 0.4 MPaDimensionsin mm (W/H/D) 260/129/366

Ordering information2.833.0020 833 IC Liquid Handling Suppressor

Unit6.1826.050*Pump tubing (white, yellow)6.1826.060 Pump tubing (orange, yellow)6.2821.120*Inline filter PEEK with 2 µm PE filter


* Already included in the standard equipment of the 833 IC Liquid Handling Suppressor Unit (2.833.0020)

833 Advanced IC Liquid Handling SuppressorUnit

The 833 IC Liquid Handling Suppressor Unit consistsof two units: • The 2-channel peristaltic pump for transporting

dilute sulfuric acid and water for regenerating and rinsing the suppressor

• The «MSM» Metrohm Suppressor Module itself,which is installed, for example, in the 820 ICSeparation Center.

Ion chromatography with Metrohm keeps two pathsopen: measurements with electronic suppressionand measurements with chemical suppression. Formeasurements with electronic suppression the out-standing electronic properties of the Metrohm 819IC Detector are utilized. These properties are alsoeffective for measurements at low background con-ductivity after chemical suppression. The «MSM»Metrohm Suppressor Module has been speciallydesigned for the analysis of anions, as suppressiononly achieves increased sensitivity in anion analysis.

The compact «MSM» Metrohm Suppressor Moduleworks with three suppressor units in a rotor. Onesuppressor unit is always in use, while the two oth-ers are being regenerated and rinsed respectively. Inthis way each chromatogram is recorded with afreshly regenerated suppressor and with an excellentreproducibility. The individual suppressors cannot bedistinguished from one another during the analysis.

The «MSM» is pressure-resistant up to 2 MPa. Higher pressures separate the two ceramic valvedisks of the «MSM» and leakage occurs. Work canbe continued as soon as the pressure returns to nor-mal values – the «MSM» again functions properly.


Online IC IC Modules – Suppressors

IC Modules – Suppressors

32

Reproducibility

A fresh suppressor is used for each measurementwith the «MSM» Metrohm Suppressor Module. Thisgives you the security that comes from knowing thatyou are always using a cation exchanger working atfull capacity: today, tomorrow and even after yearsof uninterrupted use. No sensitive membranes, nocontamination by sulfuric acid, no risk of destructionby pressure or heavy metals, no oxyhydrogen gasproduction in the laboratory: the «MSM» MetrohmSuppressor Module is favorably priced and durable.Chromatograms show that the reproducibility ofmeasurements made with the «MSM» is excellent:

30 consecutive injections, separation of the standardanions on a Metrosep A Supp 5 – 150 column, eluent 1.0 mmol/L NaHCO3, 3.2 mmol/L Na2CO3,flow 0.7 mL/min, loop 20 µL, suppression with the«MSM» Metrohm Suppressor Module, regenerationwith 50 mmol/L H2SO4, rinsing with deionizedwater.

Ion F– Cl– NO2– Br– NO3

– HPO42– SO4

2–

Concentration (mg/L) 1.00 1.00 1.00 1.00 1.00 1.00 1.00

Relative standard deviation in % (n=30) 0.46 0.33 0.37 0.37 0.32 0.41 0.37

33

With the 828 IC Dual Suppressor Metrohm has solved the equation

1 + 1 = 3

This means that you buy two suppressors and actually receive three:

• one chemical suppressor• one CO2 suppressor, and • one electronic suppressor.

The continuous mode of operation of the 828 ICDual Suppressor allows gradient systems to be realized in a simple way. The H+ cations required foranion suppression are produced electrochemically.As the 828 IC Dual Suppressor is also able to elimi-nate CO2 this opens up a whole new field of appli-cations: the flexible carbonate/hydrogen carbonatesystem can be used to the full extent without anyrestrictions. The injection and carbonate peaks arereduced to an absolute minimum. Of course, the828 IC Dual Suppressor can also be used to suppressthe conductivity of concentrated sodium and potas-sium hydroxide eluents.

Together with the unique electronic suppression ofthe Metrohm 819 Conductivity Detector, extremelylow detection limits can be achieved. It is usuallypossible to dispense with large sample loops andsample preconcentration.

828 IC Dual Suppressor

Technical informationAnion suppressorType solid-phase suppressorRegeneration electrochemicalRemote control via Remote interfaceCapacity 50 mmol/L NaOH or

equivalent at a flow of 1 mL/min

CO2 suppressorPrinciple Teflon-AF® membrane in

vacuum chamber

Dimensionsin mm (W/H/D) 260/129/366

Ordering information2.828.0010 828 IC Dual Suppressor6.2837.000*CO2 absorber cartridge

* Already included in the standard equipment of the 828 IC Dual Suppressor (2.828.0010)


Online IC IC Modules – Suppressors

IC Modules – Sample Preparation

34

Technical informationSample Preparation ModuleType «Micro Packed Bed»

cation exchangerConstruction three cartridges in one

rotorRemote control via Remote interface

PumpChannels 2Speed of rotation 20/24 min–1 (50/60 Hz)Maximum pressure 0.4 MPaDimensionsin mm (W/H/D) 260/129/366

Ordering information2.833.0030 833 IC Liquid Handling Sample

Preparation Unit6.1826.010*Pump tubing (white, white)6.2821.120*Inline filter PEEK with 2 µm PE filter


* Already included in the standard equipment of the 833 IC Liquid Handling Sample Preparation Unit (2.833.0030)

833 Advanced IC Liquid Handling SamplePreparation Unit

The unique Metrohm inline sample preparation system is the method of choice for eliminating difficult sample matrices in ion chromatography. The time-proven «MSM» technology is used with an increased capacity. The 833 IC Liquid HandlingSample Preparation Unit used for anion analysis incorporates the sample preparation steps directly in your IC system. This means that you can directlyand reliably analyze even difficult samples. A typicalexample is the determination of anions in concen-trated lyes.

Matrix elimination takes place «inline»; regenerationand rinsing are carried out in parallel «offline». The capacity of the 833 IC Liquid Handling SamplePreparation Unit is unlimited as the unit is automa-tically regenerated and rinsed after each determina-tion. The 833 IC Liquid Handling Sample PreparationUnit has been specially developed for inline samplepreparation with the 766 IC Sample Processor. It canalso be included in any other IC or HPLC systemwithout any problems.

The sample solution enters the module via a loopinjector and is rinsed with ultrapure water. In thisway the sample cations are exchanged, e.g. for protons (H+). If the sample is sodium hydroxide then water is formed by neutralization. The sampleis then transferred to the anion preconcentrationcolumn, where the trace anions to be determinedare held back, then elution again takes place withthe eluent in counterflow to transfer them to theseparating column itself where they are determined.Thanks to the high exchanger capacity even highconcentrations of cations can be reliably removed bythe 833 IC Liquid Handling Sample Preparation Unit.

The 833 IC Liquid Handling Sample Preparation Unitis controlled by the Metrodata IC Net software.

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833 Advanced IC Liquid Handling Dialysis Unit

Technical informationMembraneMaterial cellulose acetatePore size 0.2 µm, nominalMembrane thickness 115 µmDiameter 47 mm

Dialysis cellMaterial PlexiglasSolvent resistance water, ethanolCell volume 240 µL

PumpChannels 2Speed of rotation 20/24 min–1 (50/60 Hz)Maximum pressure 0.15 MPaRemote control via Remote interfaceDimensionsin mm (W/H/D) 260/129/366

Ordering information2.833.0040 833 IC Liquid Handling Dialysis Unit6.1826.030*Pump tubing (orange/yellow, i.d. =

0.5 mm) for transferring the dialyzate to the sample loop

6.1826.040*Pump tubing (black/black. i.d. = 0.76 mm) for transferring the sample

6.2714.010*Dialysis membrane, cellulose acetate; 50 pieces

6.2714.030*Dialysis membrane, polyamide; 50 pieces

* Already included in the standard equipment of the 833 IC Liquid Handling Dialysis Unit (2.833.0040)

The 833 IC Liquid Handling Dialysis Unit is the sample preparation module for numerous demand-ing applications. The determination of anions incomplex matrices is no longer a problem with the833 IC Liquid Handling Dialysis Unit. Quantitativedetermination of anions is successful in, e.g.:

• Milk,• Fruit juice, • Soil eluates, • Suspensions,• Emulsions,• and many more samples.

Dialysis is neither filtration, nor extraction, nor digestion. In dialysis the ions – and not the largerparticles (>0.2 µm) – diffuse from the sample so-lution into the acceptor solution, so that a concen-tration equilibrium is obtained. This has the advan-tage that neither the sample nor the measured val-ues are affected by a filter cake. This also meansthat matrix effects are largely eliminated.

The dialysis membrane has a working life of up toone week. Large particles which could block themembrane are simply transported past it whereasions can pass unhindered through the membrane.The pore size is approx. 0.2 µm.

Calibration of the dialysis system requires no extraeffort. Recovery and dialysis rates are easy to determine and, with the patented «stopped flow»method, are in excess of 98%.

The 833 IC Liquid Handling Dialysis Unit can becompletely automated and is controlled by theMetrodata IC Net software.


Online ICIC Modules – Sample Preparation

Dialysis is a method for separating low-molecularsubstances from higher-molecular ones («colloids»)by means of a semi-permeable membrane. Thismethod is also known under the name of «bloodwashing» and is used by patients suffering fromchronic kidney insufficiency.

Low-molecular substances in blood are ions whichaffect the electrolyte equilibrium. If the kidney is notfunctioning properly then the concentration of theions in the blood will increase and the metabolicfunctions will be adversely affected. This means thatthe concentration of the ions must be reduced atregular intervals. This is carried out by dialysis usingthe «continuous flow» method:

An acceptor solution with a very low ionic strength– usually ultrapure water – is pumped past the semi-permeable membrane. The blood flows past theother side of the membrane. As the passage of theions through the membrane is virtually unhindered,they diffuse from the blood – which has a high ionicstrength – into the acceptor solution with its lowerionic strength. As the acceptor solution is perma-nently renewed and is in «continuous flow», theconcentration gradient is very steep and the effi-ciency is relatively high. Care is deliberately takenthat the two solutions do not form a concentrationequilibrium.

Sample preparation by dialysis tries to achieve theexact opposite: The acceptor solution and samplesolution must have the same concentration in orderto achieve correct results. For this reason Metrohmhas developed the patented «stopped flow»method. As in the «continuous flow» method,

the sample solution is continuously pumped past the semi-permeable membrane. The difference isthat the acceptor solution is at rest. This means thatan equilibrium can be established between sample solution and acceptor solution. Depending on thesample matrix and the amount of higher-molecularsubstances, this normally takes place in less than ten minutes in the new Metrohm dialysis cell.

Once the equilibrium has been achieved, the accep-tor solution is transferred to the sample loop andinjected. After a total of four steps – cleaning thesystem, dialysis of the sample, transferring theacceptor solution, injecting the sample – the dia-lysis of a sample is complete. This requires about 10 minutes. The valve control of the Metrohm ICsystem allows one sample to be measured while thenext one is already being dialyzed. This saves time.

The system, like every other IC system, is easy to cal-ibrate. The dialysis rate can be determined by com-paring direct injection and dialysis. It lies in therange between 97% and 99%. We recommend thata reference standard whose peak areas are known ismeasured every day. This allows the functioning ofthe system to be checked in an easy way.

Depending on the matrix, a membrane working lifeof one week or more than one hundred injectionscan be achieved.

«Stopped flow» methodAn equilibrium is established between the acceptor solution andthe sample solution.

«Continuous flow» methodThere is no concentration equilibrium between the acceptor solution and the sample solution.

Dialysis


36

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enter the separating column also increases.Ultrafiltration using the 833 IC Liquid HandlingUltrafiltration Unit is particularly suitable for sampleswith a low to medium loading, e.g. drinking water,surface and waste water, digestion solutions, ex-tracts, etc. Uncontaminated samples can be injecteddirectly with the same sample changer, i.e. withoutfiltration. Samples with a very high loading, e.g. fruitjuices containing fruit pulp, should be prepared byusing inline sample dialysis with the 833 IC LiquidHandling Dialysis Unit, where the membrane is subjected to far less stress than in inline filtration.

The 833 IC Liquid Handling Ultrafiltration Unit iscontrolled by the Metrodata IC Net software.

Technical informationMembraneMaterial regenerated cellulosePore size 0.15 µm, nominalDiameter 47 mm

Ultrafiltration cellMaterial PlexiglasSolvent resistance water, ethanolCell volume 240 µL

PumpChannels 2Speed of rotation 20/24 min–1 (50/60 Hz)Maximum pressure 0.15 MPaRemote control via Remote interfaceDimensionsin mm (W/H/D) 260/129/366

Ordering information2.833.0050 833 IC Liquid Handling Ultrafiltration

Unit6.2714.020*Filter membrane, regenerated

cellulose; 50 pieces6.1826.070*Pump tubing (color code yellow/

yellow, i.d. = 1.4 mm) for transferringthe sample to the ultrafiltration cell

6.1826.030*Pump tubing (color code orange/ yellow, i.d. = 0.5 mm) for transferringthe filtrate to the sample loop

6.1826.010 Pump tubing (color code white/ white, i.d. = 1.0 mm) for operation without ultrafiltration

* Already included in the standard equipment of the 833 IC Liquid Handling Ultrafiltration Unit (2.833.0050)

Inline ultrafiltration is an important step on the wayto automated sample preparation in ion chromatog-raphy. Metrohm offers two different systems: the833 IC Liquid Handling Ultrafiltration Unit and the788 IC Filtration Sample Processor.

The 833 IC Liquid Handling Ultrafiltration Unit has a 2-channel peristaltic pump and the ultrafiltrationcell which, for example, is installed in the 820 ICSeparation Center.

In modern ion chromatography it is recommendedthat the sample is filtered before injection. This is toprevent very small particles from entering the sepa-rating column and blocking it. Normally membranefilters with pore sizes of 0.45 µm or less are used forthe filtration. However, the relatively high price ofsuch disposable filters limits their use, so that criticalsamples are often injected directly; this reduces theworking life of the column.

The solution is inline ultrafiltration: the sample solu-tion to be filtered flows past a membrane. At thesame time the filtrate is aspirated off from the rearside of the membrane, transferred to the sampleinjection valve of the ion chromatograph and theninjected. As only a small part of the sample is re-moved as filtrate, the majority of the contaminantsremain in the sample flow; this prevents the mem-brane from being blocked quickly.

The membrane filters supplied with the 833 ICLiquid Handling Ultrafiltration Unit have a pore sizeof 0.15 µm. You can also use any other membranewith a standard diameter of 47 mm in the ultrafiltra-tion cell. The number of samples which can beprocessed depends on the pore size and the proper-ties of the filter membrane. In general it can be saidthat an increase in the pore size results in anincrease of the working life. However, the probability thatmicroparticles will pass through the membrane and



833 Advanced IC Liquid Handling UltrafiltrationUnit


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Color code Inner diameter Flow Material(Tolerance +/-) 20 min–1 24 min–1

6.1826.010 white-white/colorless 1.02 (0.05) mm 1.41 mL/min 1.69 mL/min Tygon ST (PVC)6.1826.020 blue-blue/colorless 1.65 (0.05) mm 3.75 mL/min 4.50 mL/min Tygon ST (PVC)6.1826.030 orange-yellow/colorless 0.51 (0.05) mm 0.40 mL/min 0.48 mL/min Tygon ST (PVC)6.1826.040 black-black/colorless 0.76 (0.05) mm 0.75 mL/min 0.90 mL/min Tygon ST (PVC)6.1826.050 white-yellow/colorless 0.57 (0.05) mm 0.43 mL/min 0.52 mL/min Tygon ST (PVC)6.1826.060 orange-yellow/yellow 0.51 (0.05) mm 0.47 mL/min 0.56 mL/min PharMed (PP)6.1826.070 yellow-yellow/colorless 1.42 (0.05) mm 2.55 mL/min 3.06 mL/min Tygon ST (PVC)

6.1826.110 orange-yellow/colorless 0.49 (0.0102) mm 0.40 mL/min 0.48 mL/min Tygon LFL (PVC)6.1826.120 orange-white/colorless 0.59 (0.0101) mm 0.44 mL/min 0.53 mL/min Tygon LFL (PVC)6.1826.130 white-white /colorless 1.02 (0.0127) mm 1.41 mL/min 1.69 mL/min Tygon LFL (PVC)

Tubing for peristaltic pumps, with color code

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Online IC

The IC Column Thermostat consists of a control unitand the «IC Column Heater» column heating ele-ment which, for example, can be placed inside the820 IC Separation Center. This means that a bulkyoven alongside the IC system is not necessary.Standard columns are simply placed in the columnheating element and brought to the preset tempera-ture within a few minutes. The actual and set valuescan be read off from the control unit.

Technical informationOven temperature 30...75 °C controllable

in 0.1 °C stepsDimensions in mm (W/H/D)

Control unit 260/129/366Column heating element (outer dimensions) 40/40/262 version 0010Column heating element (outer dimensions) 40/40/412 version 0020Column heating element (inner dimensions) 20/20/210 version 0010Column heating element (inner dimensions) 20/20/350 version 0020

Can be used for columns up to (in mm; D/L) 20/170 version 0010

Can be used for columns up to (in mm; D/L) 20/320 version 0020

Ordering information2.782.0010 782 IC Column Thermostat with

IC Column Heater (210 mm)2.782.0020 782 IC Column Thermostat with

IC Column Heater (350 mm)

782 IC Column Thermostat



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Technical informationCell volume 670 µLOrganic modifier 0...100%Maximum flow 5 mL/minDimensionsin mm (W/H/D) 260/129/366

Ordering information2.837.0020 837 IC Sample Degasser

837 Advanced IC Sample Degasser

Samples which either already contain gas bubbles orthose which release gas cannot be injected directly.Gas bubbles in the system affect the baseline, causepressure variations and result in poor reproducibility.This means that manual degassing must be includedas a sample preparation step.

This step can be automated with the 837 IC SampleDegasser (version 0020).

Before the sample reaches the injection valve it passesthrough a special Teflon-AF® capillary contained in avacuum chamber. The vacuum achieves the removalof even microscopically small gas bubbles, excess carbon dioxide or nitrogen. Time-consuming manualdegassing of the sample is no longer necessary.

The 837 IC Sample Degasser (version 0020) is equipped with a large-volume vacuum chamber and, for example, allows the direct determination of drinks containing carbon dioxide without any manual sample preparation.

Thanks to the electronically controlled vacuum pump,the 837 IC Sample Degasser runs extremely quietly.

Technical informationFlow rate (peristaltic pump) 0.2...0.7 mL/min

(0.5 mL/min recommended)

Maximum counterpressure 5 barDimensions in mm (W/H/D) 89/54/150

Ordering information6.2836.000 IC Post Column Reactor

6.2836.000 IC Post Column Reactor

A small but very efficient accessory: with the «PostColumn Reactor» post column derivatization can be carried out reliably and reproducibly. The coloredreagent is added by the 833 IC Liquid HandlingPump Unit. The built-in pulsation absorber ensures a stable reagent flow. Some standard methodsrequire color reactions. With the PCR it is possible,for example, to determine chromate and bromatedown to very low concentrations. Very interestingapplication possibilities are also to be found in thefield of cation analysis with the use of UV/VIS inaddition to conductivity detection.

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820 Advanced IC Separation Center

Technical informationDimensionsin mm (W/H/D) 255/385/343

Ordering information2.820.0210 820 IC Separation Center, 1 injector

(PEEK), column heating2.820.0220 820 IC Separation Center, 2 injectors

(PEEK), column heating2.820.0230 820 IC Separation Center, 1 injector

(PEEK), «MSM», column heating2.820.0310 820 IC Separation Center, 1 injector

(PEEK)2.820.0320 820 IC Separation Center, 2 injectors

(PEEK)2.820.0330 820 IC Separation Center, 1 injector

(PEEK), «MSM»2.820.0500 IC Column Heating for 820.03X0

IC Separation Center

To convert an IC Separation Center without col-umn heating (2.820.03X0) into one with columnheating (2.820.02X0), you need the 2.820.0500 IC Column Heating and the 6.5858.000 conversionkit. The conversion can only be performed byMetrohm service personnel.

The 820 IC Separation Center provides the thermaland electrical protection for the wet-chemistry partof an ion chromatography analysis. The stablepolyurethane housing ensures temperature stability;the electrically conducting lacquer finish and themetallic network incorporated in the housing pro-vide an affective shield against electromagnetic radi-ation.

All the analytical components, with the exception of the pumps, are contained in the IC SeparationCenter. Precolumns, separating columns, preconcen-tration columns, detectors, pulsation absorber, the«MSM» Metrohm Suppressor Module and valvestherefore work under steady and constant ambientconditions. The optimal shielding of the 820 ICSeparation Center guarantees the optimal signal-to-noise behavior of the measured values. The controlelectronics are located outside the 820 IC SeparationCenter and are therefore protected against mois-ture.

The latest Separation Center generation is availablewith a built-in column oven as an option. In thiscase two separating columns together with pre-columns are kept at a constant temperature whichcan be set from 30 °C to 70 °C. As the supply capil-laries are also located in the column oven this meansthat temperature gradients within the system arereliably avoided.

The 820 Separation Center is remotely controlled bythe Metrodata IC Net software.

The 2.820.0X10 version of the IC Separation Center is equipped with an electrically-operated 6-way injection valve made from PEEK. This versionis primarily intended for cation and anion analysiswithout chemical suppression.

The 2.820.0X20 version of the IC Separation Centeris equipped with two electrically operated 6-wayinjection valves made from PEEK. This version is pri-marily suitable for combined cation and anion analy-sis systems, for inline dialysis and for systems withinline sample preconcentration or inline matrix elimi-nation. If chemical suppression is to be used then the820 Separation Center can simply be extended byadding the 833 IC Liquid Handling Suppressor Unit(2.833.0020).

In addition to the electrical 6-way injection valvemade from PEEK, the 2.820.0X30 version of the ICSeparation Center also already contains the «MSM»Metrohm Suppressor Module. This is primarily usedfor chemical suppression in anion analysis. The three«micro packed bed» suppressors contained in a rotorare characterized by their high capacity, long workinglife and simple handling: one suppressor is in theanalytical circuit, the second is regenerated withdilute sulfuric acid, and the third is rinsed with deion-ized water. After each analysis the suppressor movesone step forward so that a freshly regenerated sup-pressor is always available. The reproducibility isexcellent – the individual suppressors cannot be dis-tinguished during the analysis.

IC Modules – Liquid Handling

42

Technical informationDepending on version: either one or two 6-wayvalvesRemote control via Remote linesDimensions in mm (W/H/D) 260/129/366

Ordering information2.812.0010 812 Valve Unit with one metal-free

6-way injection valve2.812.0020 812 Valve Unit with two metal-free

6-way injection valves

812 Valve Unit

The 812 Valve Unit is used for switching eluent flowsautomatically. It is available in two versions: Version2.812.010 has an electrically operated 6-way valve,version 2.812.020 has two of them. All valve partswhich come into contact with the eluent are madefrom PEEK.

The instrument is equipped with its own power supply and can therefore be operated independently.In combination with the 816 IC Eluent Selector, the 2-valve version can be used for automatically switch-ing between two columns with intermediate rinsing.When combined with the 2.812.0020 Valve Unit andthe 816 Eluent Selector, the 761 Compact IC can be extended to form a combined anion and cationsystem. The intermediate rinsing reliably prevents theanion eluent from entering the cation column andvice versa; this accelerates the achievement of equi-librium in the columns and has a positive effect ontheir working lives.

Together with the 817 Bioscan or the 791 IC-VADetector, the 812 Valve Unit can be used as the sys-tem injection valve. It can also be used in various sam-ple preparation techniques.

43


Online ICIC Modules – Liquid Handling


44

Ordering information6.5904.0060 Internal Loop 0.25 µL (rotor)6.5904.0070 Internal Loop 1.0 µL (rotor)06.5904.0050 Internal Loop 0.25 µL (rotor)

with 4-way stator

6.5904.0X0 Internal Loop

Seawater samples, brine samples, strongly sweetenedrefreshment drinks: whenever you encounter concen-trated samples there is the risk of the separating col-umn becoming overloaded and adversely affecting thequality of the analysis. Previously such solutions hadto be diluted, either manually, inline or with a specialdilution sample changer. Now there is a new solution:the «internal loop»!

In ion chromatography 10, 20 or 100 µL of the sample is injected as standard; in contrast, the internalloop only injects either 1.0 or 0.25 µL. For example, if the 0.25 µL loop is used then the injected volume is smaller than that injected with the standard 20 µLloop by the factor 80. This means that samples in theg/L concentration range can be injected undiluted.

The internal loop or the so-called rotor can be orderedindividually with sample volumes of 0.25 or 1.0 µL. Inorder to be able to use it, the rotor built into the stan-dard 6-way injection valve is simple exchanged, the 6-way stator remains unchanged. As only four open-ings of the 6-way stator are required for working with the internal loop, this means that two of its openings must be sealed. This is why a version with a special 4-way stator is also available. In this case the rotor (0.25 µL) and stator (4-way) of the standardvalve must be exchanged. The valve drive alwaysremains unchanged.

45



Changing the column with intermediate rinsingIf in an IC system an automatic change is to be made between two different separating systems (e.g.anions with suppression and cations without suppres-sion) then we recommend that the capillaries up tothe corresponding separating column are first rinsedwith water by the IC Eluent Selector, as otherwisesmall amounts of the previous eluent could enter thenew column. This would result in stabilization timeswhich are unnecessarily long and could also evendamage the column.

Automatic column changing with intermediate rinsing can be realized with the help of an 812 ValveUnit with two 6-way valves (2.812.0020).

Technical informationThree different eluents can be used and switchedautomaticallyRemote control via RS 232CDimensions in mm (W/H/D) 260/129/366

Ordering information2.816.0010 816 IC Eluent Selector

816 IC Eluent Selector

The 816 IC Eluent Selector opens up new possibilities;these include step gradients.

With the 816 IC Eluent Selector the range of ion chromatography applications as well as the possibili-ties for automation have been considerably extended.The instrument selects one of three different solutions(eluents) with switching taking place either manuallyor automatically by using the Metrodata IC Net soft-ware. A few of these numerous applications are briefly described below.

Rinsing the IC system without manual solutionchangingIt is possible to rinse the ion chromatography systemwithout having to change the solutions manually byswitching to the rinsing solution. This prevents con-tamination of the eluent. If the rinsing step is to becarried out without the separating column then thismust be removed from the system before switchingtakes place. This can be done manually or by using an additional 6-way valve (e.g. 2.812.0010 Valve Unit).

Changing the eluent The 816 IC Eluent Selector allows eluents to be changed automatically. After equilibrium has beenachieved it is then possible to work with the same col-umn at a different selectivity. Programming in IC Netis carried out by a corresponding switching system inthe sequence.

Step gradientChanging the eluent can also take place within a single chromatogram. This means that it is possible to run a step gradient. In this way even analytes withvery different retention behaviors can be determinedin a single run. An example of such an application isthe simultaneous determination of inorganic anions as well as different carboxylic acids in fruit juices, alcoholic beverages or infusion solutions.

837 Advanced IC Eluent Degasser

Technical informationCell volume 2 x 195 µLOrganic modifier 0...100%Maximum flow 5 mL/minDimensionsin mm (W/H/D) 260/129/366

Ordering information2.837.0010 837 IC Eluent Degasser

Gas bubbles in eluents produce an unstable baselineas high-pressure pumps for ion chromatography can transport liquids but not gases. This is why it is advisable to degas eluents before use.

This can be done by using a water-jet vacuum pump or safely and quickly with the 837 IC EluentDegasser.

The degasser module is simply included between the eluent and the IC pump. The eluent then flowsthrough the special Teflon-AF® capillary, which islocated in a vacuum chamber. The vacuum removeseven microscopically small gas bubbles, excess car-bon dioxide or nitrogen. Time-consuming manualeluent degassing is no longer necessary.

The 837 IC Eluent Degasser (version 0010) isequipped with two vacuum chambers so that twoeluent flows can be degassed simultaneously.

Thanks to the electronically controlled vacuumpump, the 837 IC Eluent Degasser runs extremelyquietly.


46

The 837 IC Eluent Degasser (version 0030) isequipped with a total of three vacuum chambers sothat two eluent flows and one sample flow can bedegassed simultaneously.

Thanks to the electronically controlled vacuumpump, the 837 IC Eluent Degasser runs extremelyquietly.

837 Advanced IC Combi Degasser

Technical informationCell volume 2 x 195 µL, 1 x 670 µLOrganic modifier 0...100%Maximum flow 5 mL/minDimensionsin mm (W/H/D) 260/129/366

Ordering information2.837.0030 837 IC Combi Degasser

A powerful setup: one vacuum pump (P) evacuates three degasserunits.

Gas bubbles in eluents produce an unstable baselineas high-pressure pumps for ion chromatography can transport liquids but not gases. This is why it is advisable to degas eluents before use. A very simi-lar problem is encountered when samples whichalready contain gas bubbles or which could releasegas are to be measured. In such cases it is also necessary to remove the gas phase first.

Both the degassing of the eluents and the degassingof the samples can be carried out manually e.g. witha water-jet vacuum pump or fully automatically withthe 837 IC Eluent Degasser (version 0030).

The degasser module is simply included between the eluent and IC pump or between the sample andthe injection valve. The eluent and sample then flowthrough the special Teflon-AF® capillaries which arelocated in separate vacuum chambers. The vacuumremoves even microscopically small gas bubbles,excess carbon dioxide or nitrogen. Time-consumingmanual eluent and solvent degassing are no longernecessary.

47



Technical informationCapacity 127 x 11 mL (standard)

or 127 x 2.5 mL (optional) sample tubes plus 2 x 300 mL PE bottles (rinsing positions)

Sampling with PEEK tube (for open sample tubes) or PEEK needle (for sealed sample tubes)

Pump type 2-channel peristaltic pumpPump tubing material PVC (Tygon®)Ultrafiltration Plexiglas (polymethylmet-cell material hacrylate, PMMA)Filter membrane regenerated cellulose; material other materials can also

be usedPore Size 0.15 µmDiameter 47 mmDialysis membrane cellulose acetate; other material materials can also be usedPore size 0.2 µmDiameter 47 mmRemote interface for controlling external

devicesRS 232C interface for connecting a computer

or printerDimensionsin mm (W/H/D) 280/660/480

Filtration of the sample is intended to prevent smallparticles from entering the separating column andblocking it. Normally membrane filters with poresizes of 0.45 µm or less are used for the filtration.However, the relatively high price of such disposablefilters limits their use, so that critical samples areoften injected directly; this reduces the working lifeof the column. The 788 IC Filtration Sample Pro-cessor incorporates membrane filtration as a samplepreparation step directly in your IC system.

The samples are placed directly on the sample rackand then processed fully automatically by the 766 IC Filtration Sample Processor. The sample solutionto be filtered flows underneath a membrane fromwhose upper surface the filtrate is aspirated off atthe same time, transferred to the sample injectionvalve of the ion chromatograph and then injected.

The membrane filters supplied with the instrumenthave a pore size of 0.15 µm. You can also use anyother membrane with a standard diameter of 47 mm in the ultrafiltration cell.

Ultrafiltration using the 788 IC Filtration SampleProcessor (version 0010) is particularly suitable forsamples with a low to medium loading, e.g. drink-ing water, surface and waste water, digestion solu-tions, extracts, etc. Uncontaminated samples can beinjected directly with the same sample changer, i.e.without filtration.

Samples with a very high loading, e.g. fruit juicescontaining fruit pulp, should be prepared by usinginline sample dialysis with the IC Dialysis FiltrationSample Processor (version 0020), where the mem-brane is subjected to far less stress than in inline filtration.

788 IC Filtration Sample Processor/ 788 IC Dialysis Sample Processor

IC Modules – Sample Changers

The 788 IC Filtration Sample Processor and the 788IC Dialysis Sample Processor are freely programma-ble and fully supported by the Metrodata IC Netsoftware. The sample rack offers places for 127 x 11mL or 127 x 2.5 mL sample tubes. Two additionalrinsing positions ensure crossover-free sample injec-tion even with very different sample matrices. Theultrafiltration cell as well as the dialysis cell are madefrom Plexiglas. This has the advantage that the con-dition of the cell can always be assessed visually.

Apart from ultrafiltration and dialysis, the 788 ICFiltration Sample Processor can also be used for allother sample changer tasks as a matter of course,i.e. you can use it for direct injections, inline samplepreconcentration and inline matrix elimination. Thisprovides you with practically unlimited possibilitiesfor the automation of your ion chromatographyanalyses.

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Ordering information2.788.0010 788 IC Filtration Sample Processor2.788.0020 788 IC Dialysis Sample Processor6.2714.020* Filter membrane, regenerated

cellulose; 50 pieces6.2714.010** Dialysis membrane, cellulose

acetate; 50 pieces6.2743.050*/** PP sample tubes (11 mL);

2000 pieces6.2743.057 PP sample tubes (11 mL);

200 pieces6.2743.040 PP sample tubes (2.5 mL);

2000 pieces6.2743.047 PP sample tubes (2.5 mL);

200 pieces6.2743.070*/** PP stoppers, perforated, for

sealing sample vessels; 2000 pieces6.2743.077 PP stoppers, perforated, for sealing

sample vessels; 200 pieces6.1608.080*/** PE bottle (300 mL)6.1826.070* Pump tubing (color code yellow/

yellow, i.d. = 1.4 mm) for transferring the sample to the ultra-filtration cell

6.1826.030* Pump tubing (color code orange/ yellow, i.d. = 0.5 mm) for transferring the filtrate to the sample loop

6.1826.010 Pump tubing (color code white/ white, i.d. = 1.0 mm) for operation without ultrafiltration

6.1826.030** Pump tubing (color code orange/ yellow, i.d. = 0.5 mm) for transferring the dialyzate to the sample loop

6.1826.040** Pump tubing (color code black/ black, i.d. = 0.76 mm) for transferring the sample

* Already included in the standard equipment of the IC Filtration Sample Processor (2.788.0010)

** Already included in the standard equipment of the IC Dialysis Sample Processor (2.788.0020)


Online ICIC Modules – Sample Changers

Ordering information2.766.0010 766 IC Sample Processor6.2743.050*PP sample tubes (11 mL);

2000 pieces6.2743.057 PP sample tubes (11 mL); 200 pieces6.2743.040 PP sample tubes (2.5 mL);

2000 pieces6.2743.047 PP sample tubes (2.5 mL); 200 pieces6.2743.060 PE stoppers, 14.5 mm 1000 pieces6.2743.070*PP stoppers, 14.5 mm, 2000 pieces

(perforated)6.1608.080 PE bottle, 300 mL6.1826.040*Pump tubing (black/black)

* Already contained in the standard equipment of 766 IC Sample Processors (2.766.0010)

Technical informationCapacity 127 sample tubesRinsing positions 2Sample volume 11 mL or 2.5 mLSample needle PEEK or steelRemote control - via external keypad

- via RS 232C interface

PumpChannels 1Speed of rotation 20/24 min–1 (50/60 Hz)Maximum pressure 0.4 MPaDimensionsin mm (B/H/D) 280/660/480

766 IC Sample Processor

The 766 IC Sample Processor is the ideal samplechanger for all automation tasks in ion chromatog-raphy. No matter whether it is included in the IC system as «master» or «slave», the 766 IC SampleProcessor always ensures top performance; forexample, 127 samples can be addressed individually,the number of injections per sample is freely defin-able and rinsing steps are possible between individ-ual samples at the two included rinsing stations. Thebuilt-in peristaltic pump simplifies many automationprocedures. It transfers the sample to the IC systemor is freely addressable for other tasks such as sample preconcentration.

A sample volume of up to 11 mL also makes the766 IC Sample Processor the ideal instrument forsample preparation using dialysis. 2.5 mL sampletubes are available for smaller sample volumes.It is also possible to control the whole Metrohm ICsystem remotely from the 766 IC Sample Processor.

In this case the 766 IC Sample Processor is used asthe master and it can control any number of peripheral devices with its 14 Remote lines.The Metrodata IC Net software or the 819 IC Detector can also be used to completely control the 766 IC Sample Processor. In suchcases it is included in the IC system as a«slave». Program sequences can be createdas required by using the external keypad.

IC Modules – Sample Changers

50

813 Compact IC Autosampler

Technical informationCompact sample changer for max. 36 sampletubes. Built-in peristaltic pump, four pre-programmed sequences, separate keypad andRemote interface for connection to external devices.

Capacity 36 x 11 mL or 36 x 2.5 mL sample tubes

Pump type 1-channel peristaltic pumpPump tubing material PVC (Tygon®)Remote interface for controlling the 813

Compact IC Autosampler by an external instrument

Dimensionsin mm (W/H/D) 500/280/490

Ordering information2.813.0010 813 Compact IC Autosampler6.2743.050*PP sample tubes (11 mL);

2000 pieces6.2743.057 PP sample tubes (11 mL); 200 pieces6.2743.040 PP sample tubes (2.5 mL);

2000 pieces6.2743.047 PP sample tubes (2.5 mL); 200 pieces6.2743.060 PE stoppers, 14.5 mm 1000 pieces6.2743.070*PP stoppers, 14.5 mm, 2000 pieces

(perforated)6.1826.040*Pump tubing, PVC (Tygon®)

(color code black/black, i.d. = 0.76 mm)

* Already included in standard equipment of 813 IC Autosampler (2.813.0010)

The 813 Compact IC Autosampler is the smallerbrother of the 766 IC Sample Processor. The com-pact size, very moderate price and excellent per-formance are its outstanding features. Automationhelps to reduce your running costs. Automation alsohelps to improve the precision of your determina-tions even further. Previously the initial automationstep was frequently accompanied by very high costs.This cost factor was also one of the reasons whymany applications, which could and should havebeen carried out with ion chromatography, wereoften done using other, less suitable methods.Metrohm has now put an end to this: Today everylaboratory can afford an ion chromatograph.

Metrohm has now taken the second step by intro-ducing a sample changer which enables any ionchromatography system to be automated – withonly a moderate investment being required.

Some details of the 813 Compact IC Autosampler:This sample changer can – with the exception of the792 Basic IC – be operated with any Metrohm ionchromatograph. It works hand in hand with the 790 Personal IC, the 761 Compact IC andthe modular Metrohm IC systems. Each sample solution can be injected up tothree times. The sample rack of the 813Compact IC Autosampler has space for max. 36 samples. Polypropylenesample tubes with a volume of 11 or 2.5 mL are available; these can behermetically sealed with a stopper.The built-in peristaltic pump trans-fers the sample to the injectionvalve.

51


Online ICIC Modules – Sample Changers

It does not matter how many devices are connected– a single RS 232C line forms the connection to thePC or Notebook. This means that no alterations tothe computer hardware are required.

The construction of the interface guarantees minimalelectronic noise. The 24-bit A/D converter reliablyresolves even very small signals which reach the interface via the specially shielded D-sub-9 cable.

Technical informationRS 232C interfaces 16+1Channels 4Event lines 14A/D converter resolution 24-bitDimensionsin mm (W/H/D) 260/129/366

Ordering information2.830.0020 830 IC Interface (4 channels)

830 Advanced IC Interface

Technical informationA/D converter resolution 24-bitChannels 2 Dimensionsin mm (W/H/D) 182/78.5/165

Ordering information2.771.0010 771 IC Compact Interface

771 IC Compact Interface

Only a single cable to the PC and up to 16 IC orHPLC peripheral devices including four detectors can be controlled independently or simultaneously.The 830 IC Interface and its associated Metrodata IC Net software guarantee total system controlunder Windows™ NT, 2000 and XP.

The hardware of the 830 IC Interface is responsiblefor data acquisition and A/D conversion. The analogsignals from four channels – always two at the sametime – can be processed at high resolution. All sys-tem components – detectors, pumps, sample chang-ers – are connected to the 830 IC Interface.

The 771 IC Compact Interface forms the interfacebetween the analog signal and digital information:The built-in 24-bit A/D converter digitizes the signalfrom the detector and passes it to the COM inter-face of the computer via the RS 232C interface. The «run»-«com» information for starting datarecording is also transmitted to the Metrodata IC Net software. Two channels can be recordedindependently.

IC Modules – Interfaces and Software

52

53

The Metrodata IC Net software carries out the con-trol of all the instruments and ensures their inter-action: from the system pressure up to deliberatelyaddressing a single sample on the sample changer.Pictograms ensure clarity. New systems can be puttogether quickly and simply. More than 100 systemconfigurations are already preinstalled and can becalled up with a mouse-click.

The integration software satisfies all demands: ver-satile integration and calibration modes, batch pro-cessing and reprocessing, database functions, manu-al peak integration, statistics functions, report gen-erator, simple data export, various safety levels andcomprehensive GLP functions are only some of thepossibilities offered by the Metrodata IC Net soft-ware. The Metrodata IC Net software is compatiblewith FDA 21 CFR Part 11 as a matter of course (with Windows™ 2000 or XP).

The Metrodata IC Net software is included in theprice of the corresponding instrument.

Metrodata IC Net Software

Metrodata IC Net

Safety check on log-in. User name and password must always be entered.

Really easy system configuration with the «New System Wizard»

The new system: can be operated via pictograms per mouse-click

All system parameters online per mouse-click Clear and simple: system, chromatograms and sample queue allat a single glance.It is even easier with IC Cap!


Online ICIC Modules – Interfaces and Software

IC Modules – Interfaces and Software

54

The software which makes ion chromatographyeven easier. Even complex systems can be operatedin a very comfortable way. The principle: The ICexpert can configure the IC system in the usual way.IC Cap forms an additional user interface on top of the Metrodata IC Net software. The user will thenonly see the controls which are absolutely necessary. In the simplest case these are two buttons marked«Start» and «Stop». This means that technicians canoperate the IC system reliably after only a short peri-od of training. The Administrator is solely responsi-ble for deciding what is to be shown and what canbe operated.

• Free system configuration• Analysis start with a single mouse-click• Automatic calibration• Determination of minimum and maximum values• Freely definable error messages, e.g. «chloride

value too high»• Simple user guidance

• Greatest possible degree of operating comfort• «Any number» of dialog languages

ChineseGermanEnglishFrenchJapaneseKoreanPortugueseSwedishSpanish...

Metrodata IC Cap makes ion chromatographychild’s play.

Nothing is simpler: enter the sample name and press «Start».

Metrodata IC Cap

Metrodata AutoDatabase is the archiving programfor your chromatograms. These are stored automa-tically according to your own requirements. Searchand filter functions make the creation of overviewseasier and ensure that each detail of the determina-tions can be called up at any time. AutoDatabasesupports custom-made reports in tabular form orany other format. Automatic printout and data ex-port to Microsoft Excel are further useful programproperties.

Metrodata AutoDatabase Software

55


Online IC

Your primary interest is to have your analytical prob-lems solved properly. Metrohm offers a wide rangeof support for your applications. The simplest way to find a solution is to have a look at the Internet.On the Metrohm Website «www.metrohm.com»you will find about 300 «Application Notes» cover-ing ion chromatography that you can print out anduse directly. Methods which are suitable for theCompact IC Systems can be downloaded directlyfrom the Internet. The instrument is fully configuredafter only a few seconds.

The new Metrohm Column Leaflet contains ourrange of columns together with plenty of practicaland theoretical explanations. Our monograph«Sample preparation techniques for ion chromatog-raphy», which is also new, provides comprehensiveinformation about a sector whose importance doesnot need any further explanation.

All this information and documentation can beobtained free of charge from your local Metrohmagency. If you have any further questions pleasecontact us by normal mail or E-Mail or give us a call.Our aim is to provide you with the perfect solutionfor your particular ion chromatography problem.

Applications

Applications

Since March 2002 Metrohm AG has been sending amonthly E-Mail Newsletter to interested customersand users. This Newsletter provides you with informa-tion about our IC columns, instruments and software,describes interesting applications and informs youabout coming events and literature concerned withion chromatography: you will receive free-of-chargeand up-to-date information about everything youneed to know in the IC world.

Use this Metrohm service! The IC Newsletter is freelyaccessible to anybody who is interested. All you haveto do is fill out the corresponding form: either on ourWebsite «www.metrohm.com» or under the address«www.ic-userclub.com».

If you should decide that you do not want to receivethe IC Newsletter any more then you can log off witha mouse-click.

IC Newsletter

I o n a n a l y s i s

Metrohm Ltd.CH-9101 Herisau/SwitzerlandPhone +41 71 353 85 85 Fax +41 71 353 89 01 [email protected]


Online ICThe Whole World of Ion Chromatography

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