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The Use Of Electronic Laboratory Notebooks To Automate Manual Data Collection Processes
Robert D. WallaPresented At PITTCON 2003Orlando, FL
Astrix Technology GroupGlobal Solutions Provider To The Regulated Community
Develop And Integrate Data Develop And Integrate Data Management Solutions For Scientific Management Solutions For Scientific
OrganizationsOrganizations
Astrix Technology Group
Data Collection• LIMS Development And Customization• Instrument Workstations• PDA Applications – Remote Data Collection
Data Storage• Data Warehouse Solutions • Data Synchronization • Remote Access Via Web
Data Retrieval• Data Miming• Statistical Analysis• Reporting
Benefits Of Electronic Data CaptureBenefits Of Electronic Data Capture
Astrix Technology Group
Increases Researcher And Organizational Efficiency Increases Researcher And Organizational Efficiency Increases Quality By Eliminating Manual Data Entry and Increases Quality By Eliminating Manual Data Entry and
Resulting Transcription Errors Resulting Transcription Errors Knowledge RetentionKnowledge Retention Facilitates Access To Data Across The EnterpriseFacilitates Access To Data Across The Enterprise Decreases Product Development CyclesDecreases Product Development Cycles Decreases CostsDecreases Costs
Laboratory Automation Laboratory Automation Market ObservationsMarket Observations
Astrix Technology Group
Laboratory AutomationLaboratory AutomationThe Early YearsThe Early Years
Astrix Technology Group
Data Kept In Paper Formo Notebookso Instrument Printoutso Strip Charts
Tremendous Strides in the Automation of Analytical Techniques
Laboratory AutomationLaboratory Automation1980 - 19991980 - 1999
Astrix Technology Group
Improvements in Data Capture And Processing From Automated Instruments (i.e. Chromatography Data Acquisition Systems)
Introduction Of LIMS o Initially Internally Developed Systemso Commercial LIMS Vendorso Expanded System Functionality To Address
Administrative Requirements, i.e. Sample Tracking, Reporting, Financials, etc.
The Modern LaboratoryThe Modern Laboratory
Astrix Technology Group
Still An Incredible Volume Of Paper• Sample Prep Logs• QA/QC Logs• Observational Analysis• Diagrams/Drawings/Pictures• Researcher Notes
Electronic Laboratory Notebooks Envisioned As The Next Generation System
DriversDrivers
Astrix Technology Group
Elimination of Re-Work (30-70% in Research Environments)
Ability To Use and Share Negative Results High Throughput Screening of Materials and
Formulations Regulations Workforce Turnover/Knowledge Retention
What is an Electronic Lab Notebook?What is an Electronic Lab Notebook?
Astrix Technology Group
Mobile PDA Application? Standalone PC Application? Data Warehouse? LIMS? Document Management System? Scientific Data Management Systems?
Case StudiesCase Studies
Astrix Technology Group
Electronic Notebook That Collects Process Water Chemistry and Equipment Operational Data.
Used by Customers To More Efficiently Manage Cooling Water Systems, Including Functionality For Trend Analysis, Benchmarking and Predictive Modeling.
Case Study 1
Client: Global Water Treatment Company
Case Study 1Case Study 1Global Water Treatment CompanyGlobal Water Treatment Company
Electronic NotebookElectronic Notebook
PC Based Application Introduced in 1998 Deployed In Over 3000 Sites In 12 Countries
Used By Company Representatives Installed At Client Facilities
Provided Valuable Functionality To Client Company Used Data To Predict System Failures Reduced Total Operational Cost
Case Study 1Case Study 1
Electronic Notebook Allowed Customers To View And Analyze Trends
Case Study 1 SuccessCase Study 1 Success
A Company Vice President stated “The A Company Vice President stated “The implementation of Astrix’s system implementation of Astrix’s system leveraged over $ 7.5 million in increased leveraged over $ 7.5 million in increased sales for our Industrial Services sales for our Industrial Services Division in one year.”Division in one year.”
A Company Vice President stated “The A Company Vice President stated “The implementation of Astrix’s system implementation of Astrix’s system leveraged over $ 7.5 million in increased leveraged over $ 7.5 million in increased sales for our Industrial Services sales for our Industrial Services Division in one year.”Division in one year.”
Electronic Notebook To Collect Physical, Performance And Exposure Data On Architectural And Automotive Finishes.
Developed To More Efficiently Capture And Share Research And Development Data. Included The Integration Of Existing Data Systems.
Case Study 2
Client: Global Coatings Company
Case Study 2Case Study 2Global Coatings CompanyGlobal Coatings Company
Electronic NotebookElectronic Notebook
PDA Application Developed Using Visual Basic Used By 120 Scientists Data Synchronization To Data Warehouse Desktop Application Printed Paper Copy For Inclusion
In Paper Lab Notebook Linked Data From LIMS At Manufacturing Sites Developed Web Query Application
Case Study 2Case Study 2
Coating and Colorings Data Coating and Colorings Data WarehouseWarehouse
System TopologySystem Topology
LIMS
LIMS
Formulations Db
Test Data Entry Via Palm
Coatings and ColorantsData Warehouse
Data Access Via Brio Reports
DesktopApplication for
Excel output andsynchronization
Commercial Electronic Notebook Data Capture Product That Collects GLP Regulatory Data For Chemical Registrations. Operates in 5 Languages and Being Used Worldwide By 70% of The Agrichemical Industry.
Case Study 3
Case Study 3Case Study 3Agrichemical IndustryAgrichemical IndustryElectronic NotebookElectronic Notebook
Tablet PC Application Introduced in 1995 Used by Over 70% of the Agrichemical Market
Fortune 50 Chemical Companies Independent Contract Research Organizations
Over 7000 Trials Conducted With FieldNotes GLP Compliant Passed EPA Audits and Regulatory Submissions Operates In Five Languages
Measurable ROIMeasurable ROI
Dr. John Murphy, Director of Residue Dr. John Murphy, Director of Residue Chemistry, Bayer Corporation said "Our Chemistry, Bayer Corporation said "Our Program was budgeted at $2.41 million dollars. Program was budgeted at $2.41 million dollars. We were able to conduct the program for We were able to conduct the program for $1.43 million. We would not realized these $1.43 million. We would not realized these efficiency gains had we not had Astrix’s efficiency gains had we not had Astrix’s assistance. Even with the cost of this assistance. Even with the cost of this assistance factored in we saved $970,000.”assistance factored in we saved $970,000.”
Dr. John Murphy, Director of Residue Dr. John Murphy, Director of Residue Chemistry, Bayer Corporation said "Our Chemistry, Bayer Corporation said "Our Program was budgeted at $2.41 million dollars. Program was budgeted at $2.41 million dollars. We were able to conduct the program for We were able to conduct the program for $1.43 million. We would not realized these $1.43 million. We would not realized these efficiency gains had we not had Astrix’s efficiency gains had we not had Astrix’s assistance. Even with the cost of this assistance. Even with the cost of this assistance factored in we saved $970,000.”assistance factored in we saved $970,000.”
Case Study 3
Astrix Technology Group
Despite The Advance In Automation There Remains Despite The Advance In Automation There Remains
Significant Manual Data Collection Processes Significant Manual Data Collection Processes
Electronic Notebooks Are “What You Need Them To Be” Electronic Notebooks Are “What You Need Them To Be”
Technology (Hardware/Software) Is Available And Technology (Hardware/Software) Is Available And
ImprovingImproving
Progressive Companies Are Taking Iterative Steps And Progressive Companies Are Taking Iterative Steps And
Realizing Near Term Benefits and ROI Realizing Near Term Benefits and ROI
ConclusionsConclusions
Astrix Technology Group
Comments or Questions:
Robert D. Walla 732-661-0400
www.astrixsoftware.com
Astrix Technology GroupGlobal Solutions Provider To The Regulated Community