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The Relationship of Urologic Complications With Health- Related Quality of Life and
Perceived Value of Health in Men and Women with Type 1 Diabetes: The Diabetes Control and
Complications Trial/Epidemiology of Interventions and Complications (DCCT/EDIC)
Cohort
Featured Article:
Alan M. Jacobson, Barbara H. Braffett, Patricia A. Cleary, Rodney L. Dunn, Mary E. Larkin, Hunter Wessells, Aruna V. Sarma, and the
DCCT/EDIC Research Group
Diabetes Care Volume 38: 1904-1912
October, 2015
STUDY OBJECTIVE
• Limited information exists about the influence of urologic complications on health-related quality of life (HRQOL) in patients with type 1 diabetes
Jacobson A. M. et al. Diabetes Care 2015;38:1904-1912
STUDY DESIGN AND METHODS
• 664 men and 580 women from the Diabetes Control and Complications Trial/Epidemiology of Interventions and Complications Study were studied
• The following were assessed:
• Associations of sexual dysfunction• Lower urinary tract symptoms (LUTS)• In women, urinary incontinence (UI) with general quality of
life, perceived value of health, diabetes-related quality of life (Diabetes Quality of Life Scale [DQOL]), and psychiatric symptoms
Jacobson A. M. et al. Diabetes Care 2015;38:1904-1912
RESULTS
• In men and women, urologic complications adversely affected HRQOL and psychiatric symptoms
• Multivariable analyses accounting for the presence of diabetic retinopathy, neuropathy, and nephropathy also revealed substantial independent effects
• In men, the odds of a low DQOL score were 3.01 times greater with erectile dysfunction and 2.65 times greater with LUTS
• In women, the odds were 2.04 times greater with sexual dysfunction and 2.71 times greater with UI/LUTS combined
Jacobson A. M. et al. Diabetes Care 2015;38:1904-1912
Jacobson A. M. et al. Diabetes Care 2015;38:1904-1912
CONCLUSIONS
• Sexual dysfunction and urinary complications with type 1 diabetes are associated with:
• Decreased quality of life• Decreased perceived value of health• Higher levels of psychiatric symptoms
Jacobson A. M. et al. Diabetes Care 2015;38:1904-1912
Jacobson A. M. et al. Diabetes Care 2015;38:1904-1912
Jacobson A. M. et al. Diabetes Care 2015;38:1904-1912
Jacobson A. M. et al. Diabetes Care 2015;38:1904-1912
