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CORESTA Oct 2015
The relationship of tobacco specific nitrosamine (TSNA) levels with relative humidity during curing in U.S. burley LION K.; LUSSO M.; MORRIS W. and HART F.
Altria Client Services l Biotechnology l 10/26/2015 l Draft l Confidential 1
Altria Client Services LLC Research, Development & Engineering 601 East Jackson Street Richmond VA 23219
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Burley TSNA Sampling Program Overview Objective: To monitor annual TSNA levels of U.S. burley
Sampling Program: - Initiated in 2010 - Representative bales were selected and tagged at receiving station
for testing - Tagged bales were cored and samples were analyzed for TSNA
Altria Client Services l Biotechnology l 10/26/2015 l Draft l Confidential 2
Crop Year Analytical Samples
2010 3,576
2011 3,276
2012 769
2013 1,487
2014 2,197
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U.S. Burley Crop TSNA Levels – 2010-2014
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Receiving Station Locations
Altria Client Services l Biotechnology l 10/26/2015 l Draft l Confidential 4
Hopkinsville
Elizabethtown Danville
New Holland
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U.S. Burley Crop TSNA Levels – By Receiving Station
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Relative Humidity Data Collection Relative humidity, specifically during the first few weeks of
curing, has been cited as a potential factor in TSNA formation
Relative humidity data were analyzed from the last week of August through the first week of October using http://www.wunderground.com
There were 9 to 38 weather stations within the tobacco production region for each receiving station
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Weather Station Coverage Map
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Hopkinsville
Map created using: http://batchgeo.com
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Weather Station Coverage Map
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Map created using: http://batchgeo.com
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Weather Station Coverage Map
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Map created using: http://batchgeo.com
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Altria Client Services l Biotechnology l 10/26/2015 l Draft l Confidential 10
TSNA Correlation with Relative Humidity
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TSNA Correlation with Relative Humidity
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TSNA Correlation with Relative Humidity
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TSNA Correlation with Relative Humidity
Corresponding nitrate data collected for 12 of 18 highlighted data points
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TSNA Correlation with Relative Humidity
Nitrate range = 26,740 – 33,715 ppm
New Holland 2013, 2014
Nitrate range = 17,104 – 17,493 ppm
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TSNA Correlation with Relative Humidity
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Conclusions U.S. burley crop TSNA levels vary greatly from year to year as
well as across different geographic regions within a given year
Data suggests a strong correlation between TSNA levels and relative humidity conditions during early stages of curing
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