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The Red Eye Differential Diagnosis

The Red Eye - International Council of OphthalmologyDifferential Diagnosis of “red eye” Conjunctiva Pupil Cornea Anterior chamber IOP Subconjunctival Haemorrhage Bright red Normal

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Page 1: The Red Eye - International Council of OphthalmologyDifferential Diagnosis of “red eye” Conjunctiva Pupil Cornea Anterior chamber IOP Subconjunctival Haemorrhage Bright red Normal

The Red EyeDifferential Diagnosis

Page 2: The Red Eye - International Council of OphthalmologyDifferential Diagnosis of “red eye” Conjunctiva Pupil Cornea Anterior chamber IOP Subconjunctival Haemorrhage Bright red Normal

Differential Diagnosis of “red eye”

Conjunctiva

Pupil Cornea Anterior chamber

IOP

Subconjunctival Haemorrhage

Bright red Normal Normal Normal Normal

Conjunctivitis Injected vessels, fornices.

Discharge

Normal Normal Normal Normal

Iritis Injected around cornea

Small, fixed,

irregular

Normal, KPs

Turgid, deep

Normal

Acute glaucoma Entire eye red Fixed, dilated,

oval

Hazy Shallow High

Page 3: The Red Eye - International Council of OphthalmologyDifferential Diagnosis of “red eye” Conjunctiva Pupil Cornea Anterior chamber IOP Subconjunctival Haemorrhage Bright red Normal

Conjunctivitis

Follicles Purulent dischargePapillae

ChemosisRedness

Page 4: The Red Eye - International Council of OphthalmologyDifferential Diagnosis of “red eye” Conjunctiva Pupil Cornea Anterior chamber IOP Subconjunctival Haemorrhage Bright red Normal

Subconjunctival Haemorrhage

• Diffuse or localised area of blood under conjunctiva. Asymptomatic

• Idiopathic, trauma, cough, sneezing, aspirin, HT

• Resolves within 10-14 days

Page 5: The Red Eye - International Council of OphthalmologyDifferential Diagnosis of “red eye” Conjunctiva Pupil Cornea Anterior chamber IOP Subconjunctival Haemorrhage Bright red Normal

Dry Eye Syndrome

• Poor quality – Meibomian gland disease,Acne rosacea– Lid related– Vitamin A deficiency

• Poor quantity– KCS

• Sjogren Syndrome• Rheumatoid Arthritis

– Lacrimal disease ie, Sarcoidosis– Paralytic ie, VII CN palsy

Page 6: The Red Eye - International Council of OphthalmologyDifferential Diagnosis of “red eye” Conjunctiva Pupil Cornea Anterior chamber IOP Subconjunctival Haemorrhage Bright red Normal

Corneal Abrasion

• Surface epithelium sloughed off. • Stains with fluorescein• Usually due to trauma• Pain, FB sensation, tearing, red eye

Page 7: The Red Eye - International Council of OphthalmologyDifferential Diagnosis of “red eye” Conjunctiva Pupil Cornea Anterior chamber IOP Subconjunctival Haemorrhage Bright red Normal
Page 8: The Red Eye - International Council of OphthalmologyDifferential Diagnosis of “red eye” Conjunctiva Pupil Cornea Anterior chamber IOP Subconjunctival Haemorrhage Bright red Normal

Corneal Ulcer

• Infection– Bacterial: Adnexal infection, lid malposition,

dry eye, CL– Viral: HSV, HZO– Fungal:– Protozoan: Acanthamoeba in CL wearer

• Mechanical or trauma• Chemical: Alkali injuries are worse than acid

Page 9: The Red Eye - International Council of OphthalmologyDifferential Diagnosis of “red eye” Conjunctiva Pupil Cornea Anterior chamber IOP Subconjunctival Haemorrhage Bright red Normal
Page 10: The Red Eye - International Council of OphthalmologyDifferential Diagnosis of “red eye” Conjunctiva Pupil Cornea Anterior chamber IOP Subconjunctival Haemorrhage Bright red Normal

Episcleritis

• Superficial• Idiopathic, collagen

vascular disorder (RA)• Asymptomatic, mild

pain• Self-limiting or topical

treatment

Page 11: The Red Eye - International Council of OphthalmologyDifferential Diagnosis of “red eye” Conjunctiva Pupil Cornea Anterior chamber IOP Subconjunctival Haemorrhage Bright red Normal

Scleritis

• Deep • Idiopathic• Collagen vascular disease (RA,AS, SLE,

Wegener, PAN) • Zoster • Sarcoidosis• Dull, deep pain wakes patient at night• Systemic treatment with NSAI or Prednisolone if

severe

Page 12: The Red Eye - International Council of OphthalmologyDifferential Diagnosis of “red eye” Conjunctiva Pupil Cornea Anterior chamber IOP Subconjunctival Haemorrhage Bright red Normal
Page 13: The Red Eye - International Council of OphthalmologyDifferential Diagnosis of “red eye” Conjunctiva Pupil Cornea Anterior chamber IOP Subconjunctival Haemorrhage Bright red Normal
Page 14: The Red Eye - International Council of OphthalmologyDifferential Diagnosis of “red eye” Conjunctiva Pupil Cornea Anterior chamber IOP Subconjunctival Haemorrhage Bright red Normal

Uveitis

Anterior: acute recurrent and chronicPosterior: vitritis, retinal vasculitis, retinitis,

choroiditisPanuveitis:anterior and posterior

Page 15: The Red Eye - International Council of OphthalmologyDifferential Diagnosis of “red eye” Conjunctiva Pupil Cornea Anterior chamber IOP Subconjunctival Haemorrhage Bright red Normal

Anterior uveitis (iritis)

• Photophobia, red eye, decreased vision• Idiopathic. Commonest• Associated to systemic disease

– Seronegative arthropathies:AS, IBD, Psoriatic arthritis, Reiter’s

– Autoimmune: Sarcoidosis, Behcets– Infection: Shingles, Toxoplasmosis, TB,

Syphillis, HIV

Page 16: The Red Eye - International Council of OphthalmologyDifferential Diagnosis of “red eye” Conjunctiva Pupil Cornea Anterior chamber IOP Subconjunctival Haemorrhage Bright red Normal

Ciliary flush

Posterior synechiae

KPs

Fibrin

Hypopyon

Flare

Page 17: The Red Eye - International Council of OphthalmologyDifferential Diagnosis of “red eye” Conjunctiva Pupil Cornea Anterior chamber IOP Subconjunctival Haemorrhage Bright red Normal
Page 18: The Red Eye - International Council of OphthalmologyDifferential Diagnosis of “red eye” Conjunctiva Pupil Cornea Anterior chamber IOP Subconjunctival Haemorrhage Bright red Normal

Acute Angle-closure Glaucoma

• Symptoms– Pain, headache,

nausea-vomiting– Redness, photophobia, – Reduced vision– Haloes around lights

Corneal oedema

Ciliary hyperaemiaDilated pupil

Page 19: The Red Eye - International Council of OphthalmologyDifferential Diagnosis of “red eye” Conjunctiva Pupil Cornea Anterior chamber IOP Subconjunctival Haemorrhage Bright red Normal
Page 20: The Red Eye - International Council of OphthalmologyDifferential Diagnosis of “red eye” Conjunctiva Pupil Cornea Anterior chamber IOP Subconjunctival Haemorrhage Bright red Normal
Page 21: The Red Eye - International Council of OphthalmologyDifferential Diagnosis of “red eye” Conjunctiva Pupil Cornea Anterior chamber IOP Subconjunctival Haemorrhage Bright red Normal
Page 22: The Red Eye - International Council of OphthalmologyDifferential Diagnosis of “red eye” Conjunctiva Pupil Cornea Anterior chamber IOP Subconjunctival Haemorrhage Bright red Normal