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in some of them, but simple cancer had the infiltration through the scar t issue of the ulcer in all of them.

On the other hand, intramucous infiltration was limited in the macroscopical regions in adenocarcinoma, but extended over the macroscopical regions in simple cancer.

23. T H E P O L Y P O I D L E S I O N S O F T H E S T O M A C H W I T H S P E C I A L

R E F E R E N C E TO A T Y P I C A L E P I T H E L I A L L E S I O N S

K. Takagi, K. Kumakura*, K. Nakamura, H. Sugano**

* Surgery, and Medical Clinic, Cancer Institute Hospitai ** Department of Pathology, Cancer Institute

There were some confusions on the clinical diagnosis by that the clinical diagnosis was divided into benignity and malignity on the polypoid lesions of the stomach. So we want to consider the atypical epithelial lesions as the so-called border-line cases between benign and malignant lesions.

The purpose of the present study is to show that the clinicopathological study of the potypoid lesions concerning the shape of elevation and the figure of border. There was clear difference between benign polypoid lesions without atypical epithelium and early carcinomas or atypical epithelial lesions. That is, most benign polypoid lesions showed that their shape of elevation was hemi-spheric or spheric and their border was smooth and round, but early carcinomas and atypical lesions showed that the elevation was plateau-like and the border was irregular like chrysanthemum.

The age distributions of atypical epithelial lesions were most frequently observed in aged people over the 6os.

On the size of atypical epithelial lesions, the small lesions, measuring less than 2cm, were most commenly, but the lesions more than 2.1cm in diameter were rare.

24. P A T H O L O G I C A L S T U D Y O F E A R L Y C A N C E R I N S T O M A C H

I. Murata, M. Hatakeyama, S. Maeda, T. Hirono, Y. Saeki

The First Surgical Division, Toyama Central Hospital

I believe that gastric polyp are not to be grown over some extent in principle. If they grew up to over some extent, it is essential that there should be the addition of some condition to gastric polyp. These conditions include self controlled production of polyp, malignant alteration and imflammatory changes.

From a point of these view, we have studied 148 protruded lesions and 72 early carcinomas which are obtained from 2300 resected stomach.

Stalked lesions are susceptible to 'reduce the circulatory obstruction at these distal end morphorogically. And the inflammatory reaction, edema and hemorrhage were seen in the large majority of these lesions. In consequence, these make a mushroom appearance and mostly, shows a regenerative polyp pathologically.

On the contrary, wide-basic short stalked protruded lesions are mostly the adenomatous polyp and have a tendency to independent growing.

In a comparison of both of them by diameter in lesions, the stalked ',polyps in the over 1.5 cm revealed commonly atypism and showed usually adenomatous. Also the stalked polyps in the below 1.5cm showed commonly regenerative and focal malignant alteration was demon- strated in only one lesion of 66.

But the valley-like or hemispheric protruded lesions showed focal malignant alteration in some instances, even if they present more smaller than 1.5 cm in diameter and in such lesions that are 1.5cm or larger in diameter, we have never demonstrated the early carcinoma. If, by any chance, such lesions are carcinoma, they are advanced cancer.

Thirty-two of 72 early carcinomas were the caved ulcerated lesion. Of these, the ulcer