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1 This document contains confidential and proprietary information of Mylan N.V. Unauthorized use, duplication, dissemination or disclosure to third parties is strictly prohibited. © 2016 1 This document contains proprietary information of Mylan N.V. Unauthorized use, duplication, dissemination or disclosure to third parties is strictly prohibited. © 2017
The Mylan StoryUNIT-8VIZIANAGARAM
2 This document contains confidential and proprietary information of Mylan N.V. Unauthorized use, duplication, dissemination or disclosure to third parties is strictly prohibited. © 2016 2 This document contains proprietary information of Mylan N.V. Unauthorized use, duplication, dissemination or disclosure to third parties is strictly prohibited. © 2017
At Mylan,We are committed to setting new standards in
healthcare.
Working together around the world to provide 7 billion
people access to high quality medicine
7B:1
Products offered in >165 countries
Ship to ~60,000 customers
>35,000 passionate Workforce
~80% volume internally produced
More Than Just Words
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Operational Scale
Facilities
Doses Units Units Kiloliters
80B 500M 1.5B 4,800
Oral Solid Doses Injectables Complex Products API
24 Facilities 9 Facilities 8 Facilities 9 Facilities
A global healthcare company with an unmatched platform
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Site Overview: Unit-8, Vizianagaram
Manufacturing site was established in 1993 to produce
Active Pharma Ingredients (APIs)
Plant Capacity Approvals Accreditations
Kiloliters
1,172
Built-up Area
57%Total Factory Area
2,75,992 m2
Green Belt
33% 10%Expansion
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Major Equipment P R O C E S S E Q U I P M E N T
286 Reactors(GLR & SS) PROCESS TYPE:
Manufacturing of APIs
Manufacturing Blocks11
1172 KL of Reactor Volume
80 Centrifuges
56 Vacuum Tray Driers
32 Tray Driers
U T I L I T Y E Q U I P M E N T
16 +5 Chillers 1715 TR
03 -10 Chillers 186 TR
14 -20 Chillers 604 TR
05 Nitrogen Plants 800 N3/Hr
05 Dry Air Plants: 1180 CFM
14 Cooling Towers : 8250 TR
6 This document contains confidential and proprietary information of Mylan N.V. Unauthorized use, duplication, dissemination or disclosure to third parties is strictly prohibited. © 2016 6 This document contains proprietary information of Mylan N.V. Unauthorized use, duplication, dissemination or disclosure to third parties is strictly prohibited. © 2017
ENERGY MANAGEMENT SYSTEM
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Energy Management System at Site
Energy Management System (EnMS) Policy was
established in year 2013 and developed:
Implementation, Reporting & Monitoring
Methodologies
Created extensive Awareness among Employees
via. Training, Indoor/Outdoor Posters & Contests
Equipped with In-House Energy Monitoring &
Measuring Devices
Designed Procurement strategy in tune with Asset
life cycle cost assessment
Extensively exploring Renewable Solar energy via
Solar Power Purchasing Agreement (PPA)
In-house 10 KW Rooftop Solar grid system &
also Water Heaters
Implemented various Innovative Energy saving
projects at Site
Mylan has received ISO-50001 CERTIFICATION in July-16
23 Internal auditors were nominated and trained by DNV.GL.
41 Members were elected as Energy Core Committee team
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EnMS Policy IS0-50001 Certification
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EnMS Implementation
Methodology
EnMS Implementation Methodology
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EnMS Reporting Methodology
20
51
0 10 20 30 40 50 60
OPEN
CLOSED
ESO REPORTED FROM JULY-17
Energy Aspects Identification
➟ Energy usage Register
➟ Feed back from Inspection team/Operator
➟ ESO Format
➟ Review Meetings/Internal Audits
➟ Feed back from Other Units
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EnMS Monitoring Methodology
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Awareness Programs at Site
Display Posters Trainings
Energy Conservation
Day Contest
Name of Entry No of EntriesDrawing contest 70Essay contest 61Slogan contest 124Suggestion Contest 165Total 420
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In-House Energy Monitoring & Measuring Devices
13
Best tool for to check the pump performance to optimize Chilling plants and
other systems
Locate, measure the Air/Nitrogen/Vacuum leakages/condition of valve and
steam traps
Generate reports that simplify our energy management tasks (Voltage,
Current, Frequency, Harmonics, Power factor, Active & Reactive power etc.,)
Measure hot & cold surfaces and bearing temperatures
Ultrasonic flowmeter – Speedy flow measurement
Ultra probe leak detector
Power analyzer
Thermal image scanner & infrared thermometer
14 This document contains confidential and proprietary information of Mylan N.V. Unauthorized use, duplication, dissemination or disclosure to third parties is strictly prohibited. © 2016 14 This document contains proprietary information of Mylan N.V. Unauthorized use, duplication, dissemination or disclosure to third parties is strictly prohibited. © 2017
Energy Mapping for 2016
Electricity Demand Electricity SupplyDG Power
2%
Solar Power
11%
Captive Power23%
Govt. Power65%
Admin.1%
Solvent recovery
1%EHS9%
QC & QA4%
Warehouse2%
Mfg.27%
Utilities56%
Energy
Intense Areas
Chilling Plants
Boiler
Compressed Air
Non-Renewable
Resources
Consumption
Coal - 58,750 Tons
Diesel - 339 KL
631Lakh Units
Consumed
in 2016
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16 This document contains confidential and proprietary information of Mylan N.V. Unauthorized use, duplication, dissemination or disclosure to third parties is strictly prohibited. © 2016 16 This document contains proprietary information of Mylan N.V. Unauthorized use, duplication, dissemination or disclosure to third parties is strictly prohibited. © 2017
Renewable Energy Usage at Site
In-House Solar Power Generation SystemsExternal Solar Power
93,72,021 KWHPurchased during
Apr’16 - Mar’17
Rooftop Solar on grid system
System capacity :10 KW
Annual Production:13500 KW
Installed : Dec-15
Investment : Rs. 6 Lac
Solar Water Heaters
No. of Systems : 10 Nos
System capacity : 200 LPD
Energy Savings :27000 KWH
Installed : Dec-16
Investment : Rs. 5 Lac
17 This document contains confidential and proprietary information of Mylan N.V. Unauthorized use, duplication, dissemination or disclosure to third parties is strictly prohibited. © 2016 17 This document contains proprietary information of Mylan N.V. Unauthorized use, duplication, dissemination or disclosure to third parties is strictly prohibited. © 2017
ENERGY SAVING PROJECTS
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Chillers
Chiller ID Commissioned Running days
CH-1825 Dec-15 613
CH-1823 Dec-15 610
CH-1807 April-16 512
CH-1808 Aug-16 389
CH-1806 Aug-16 387
CH-1829 Aug-16 386
CH-1837 Aug-16 385
CH-1832 Aug-16 372
CH-1818 Sept-16 363
CH-1816 Sept-16 352
CH-1833 Sept-16 348
CH-1812 Sept-16 342
CH-1830 Nov-16 296
CH-1831 Nov-16 294
CH-1805 Nov-16 275
Pumps
PLC with skidControl valves
Sponge ballMulti color HMI
Innovative Project - I: Online Tube Cleaning System (1/3)
12% Energy Efficiency Improved in Water Cooled Chillers
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Innovative Project - I: Online Tube Cleaning System (2/3)
[VALUE]%[VALUE]% [VALUE]% [VALUE]% [VALUE]% [VALUE]% [VALUE]%
[VALUE]%[VALUE]%
[VALUE]% [VALUE]%[VALUE]% [VALUE]%
[VALUE]%
80
82
84
86
88
90
92
1 2 3 4 5 6 7
% o
f IP
A R
ecov
ery
Percentage of Solvent Recovery
Before After
ATCS for Turbine Condenser Solvent Recovery Plant
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Innovative Project - I: Online Tube Cleaning System (3/3)
UoM Co-Gen Chillers SRP
Investment Lakh INR 16 45 24
Annual savings Lakh INR 23.6 53.4 180
Annual Energy saving Units -- 8,90,000 32,553
Annual Coal
savings Tons 701 -- 717
ROI Months 8 10 2
Advantages
➟ Continuously operating at maximum
Efficiency.
➟ 12% Energy Efficiency Improvement in
Water Cooled Chillers
➟ Avoids two shutdowns in turbine
generator.
➟ 4-5 % reduction in solvent losses in
Solvent Recovery plant.
➟ Fully automatic.
➟ Ensures 100% clean tubes.
➟ Single System for Multiple Heat
Exchangers.
➟ No water wastage.
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Innovative Project - II: Water Management Initiative (1/2)
WATER CONSERVATION DATA
(Unit-8)
Total number of Needle type
aerators Installed100 Nos
Water savings per day 18 KL
Water savings per year 6678 KL
Annual water cost savings 2.5 Lakhs
Annual Effluent treatment cost 18 Lakhs
Annual Energy cost Savings 0.4 Lakhs
Total cost savings per year 21 Lakhs
capital cost Taps 0.3 lakhs
ROI 5 days
New innovative Needle type
aerators were installed for
washbasin taps
Com
pari
son
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Innovative Project - II: Water Management Initiative (2/2)
New innovative Needle type
aerators were installed for
washbasin taps
WATER CONSERVATION DATA(Unit - 1, 2, 3, 7, 8, 9, 10, 11, 12, Corporate and R&D)
Total number of Needle type
aerators Installed478 Nos
Water savings per day 80 KL
Water savings per year 28,335 KL
Annual water cost savings 16 Lakhs
Annual Effluent treatment cost 72 Lakhs
Annual Energy cost Savings 1.2 Lakhs
Total cost savings per year 90 Lakhs
Capital Cost for Taps 1 lakhs
ROI 4 days
Com
pari
son
Implemented at all Mylan
API Units, Corporate and R&D
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Innovative Project - III: Water Cooled Split Air Conditioner
3 star split Air ConditionerWater cooled split air
conditioner
R-22 gas R-410A gas
Heat recovery not possibleHeat recovery from outdoor unit
(Annual Coal Savings 50 Tons)
280-290 Electrical units/day 100-110 Electrical units/day
➟ Investment : 10 Lakhs
➟ Annual Savings : 07 Lakhs
➟ Annual Energy savings: 66,267 KWH
➟ Annual Coal Savings : 50 Tons
➟ ROI : 17 months
Water Cooled AC Layout in Turbine room
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Innovative Project - IV: Innovative Cleaning Solutions
Adopted innovating cleaning solutions for maximizing efficiency in Air cooled HVAC chillers,
Condensing units, Air conditioners, Air compressors & Diesel generators.
Coil Jet Mini split bib kit Flow jet
Carries all the water and
cleaning AC indoor, out door and
condensing units up to 5 Ton.
Clean the indoor unit of AC with
combination of coil jet. Keeps walls &
floors safe from water and over spray
It easy to clean HVAC coils,
evaporator coils and large air-
cooled refrigeration units
25 This document contains confidential and proprietary information of Mylan N.V. Unauthorized use, duplication, dissemination or disclosure to third parties is strictly prohibited. © 2016 25 This document contains proprietary information of Mylan N.V. Unauthorized use, duplication, dissemination or disclosure to third parties is strictly prohibited. © 2017
Energy Management Initiatives
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Initiative - 1: Energy efficient Dry Air systems
26
Pressure drop across the Drier < 0.2 bar
Installed in 2015 Year
Investment made 101 Lakhs
Annual energy savings 8,33,000 KWH
Annual Cost savings 50 Lakhs
ROI 24 Months
Adjustable Dew point settings
VFD compressor and blower
Zero purge loss heated Drier
Dew point based tower change over
Uni
quen
ess
of th
e Sy
stem
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Initiative - 2: Process Operational Controls
On/Off Control valves for Vacuum Tray Driers
Manual ON/OFFcontrol valve
Pharma area
➟ Implemented year : 2015 & 16
➟ No. of Vacuum tray driers : 66 Nos
➟ Investment made : 7.9 Lakhs
➟ Annual Energy Savings : 1,83,000 Units
➟ Annual cost savings : 11 Lakhs
➟ ROI : 9 Months
Elimination of idle running in vacuum
pumps and hot water pumps during
sampling, loading and unloading time
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Initiative - 3: Retro fitting of bubbling bed systemB
ub
bli
ng
bed
Bo
iler
Auto fuel feeding
Efficiency improved from 60% to 80%
Improvement in Coal handling
Alternative fuel option
Ad
van
tag
es
Installed in 2014 Year
Investment made 90 Lakh Rupees
Annual Cost savings 220 Lakh Rupees
ROI 5 Months
5 TPH Boiler
Man power reduction
4 TPH Boiler
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Initiative - 4: Chilling Plant Automation
Control panels provided for reciprocating
Chillers 12 no's to make precise control of
operation including primary pumps.
➟ Implemented year : 2015
➟ Investment made : 12 Lakhs
➟ Annual energy savings : 18 Lakhs
➟ ROI : 8 Months
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Initiative - 5: Optimization of Air compressors by eliminating
Unload Power
➟ Implemented year : 2015
➟ No of Drying plants : 03 Nos
➟ Investment made : 13 Lakhs
➟ Annual savings : 11 Lakhs
➟ Annual Energy savings : 1.83 Lakh KWH
➟ ROI : 14 months
Drying Plants unload power is eliminated by
providing Variable frequency drive.
Precise control of operation and constant
pressure supply at user end
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Initiative - 6: Retrofit VFD solution Nitrogen Plant
➟ Implemented Year : 2015
➟ Investment made : 8 Lakhs
➟ Annual savings : 12 lakhs
➟ Annual Energy savings : 1,93,300 KWH
➟ ROI : 8 Months
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Initiative - 7: Back Pressure Turbine
➟ Implemented Year : 2016
➟ Investment made : 20 Mn
➟ Annual savings : 29.5 Mn
➟ Annual coal savings : 9100 Tons
➟ Water Savings : 7000 KL
➟ ROI : 8 Months
A. 5 Tons/hr process steam additionally available from the co-gen plant
B. Auxiliary power consumption reduction 22 Lakh Units per Year
EXISTING SYSTEM PROPOSED SYSTEM
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Initiative - 8: Heat Recovery System for 4&5 TPH Boilers
➟ Implemented Year : 2016
➟ Investment made : 23 Lakhs
➟ Annual savings : 22 Lakhs
➟ Annual Coal savings : 515 Tons
➟ ROI : 13 Months
Pressurized deaerator installed to utilize the heat content in flash
steam & to reduce the fuel consumption in boiler by increasing
boiler feed water temperature
Installed Pressurized De-aerator instead of Natural De-aerator
➟ Implemented Year : 2016
➟ Investment made : 8.5 Lakhs
➟ Annual savings : 9 Lakhs
➟ Annual Coal savings : 263 Tons
➟ ROI : 12 Months
Installed APH instead WPH to utilize waste heat from flue gases to
increase air temperature from 35 To 90°C
Installed Air Preheater instead of water Pre heater for 4 & 5T boilers
5 TPH Boiler 4 TPH Boiler
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Initiative - 9: Energy Efficient Chillers
➟ Implemented Year : 2016 & 2017
➟ Investment made : 55 Lakhs
➟ Annual Energy savings : 45 Lakhs
➟ ROI : 15 Months
Installed Energy Efficient water cooled Screw type Chiller in
place of 3 reciprocating Chillers
Capacity : 90TR@ -20°C and 83TR @ -20°C
Location : Utility-1 &7
Higher capacity efficient, dual mode, Water
cooled, Variable speed screw type Chiller
➟ Precise capacity control with VFD
➟ Step-less capacity control from 100% to 25%
➟ Improved power factor
IMPROVEMENTS
IN DESIGN
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Initiative - 10: Cooling Towers
➟ Implemented Year : 2013 & 2015
➟ Total number of fans arranged : 23 Nos
➟ Investment made : 8 Lakhs
➟ Annual cost savings : 10 Lakhs
➟ ROI : 10 Months
Replaced aluminum blades with FRP blades for all utility
blocksFRP fan blade
VFD for CT fan
➟ Implemented Year : 2013, 2015 & 2016
➟ Total number of VFDs arranged : 22 Nos
➟ Investment made : 8.8 Lakhs
➟ Annual cost savings : 12 Lakhs
➟ ROI : 9 Months
Provided variable frequency drive for Cooling tower fans
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Zero Investment Initiatives
➟ Implemented Year : 2014
➟ Annual cost savings : 4.2 Lakhs
➟ Annual Energy Savings : 70,000 KWH
Modulated the operating pressure of Air Compressors of Nitrogen plant
✏ Equipment : NT-1802, 1803, 1804, 1805
✏ Before Modification : 6.0 to 7.0 kg/cm2
✏ After Modification : 5.8 to 6.4 kg/cm2
➟ Implemented Year : 2014
➟ Annual cost savings : 8.1 Lakhs
➟ Annual Energy Savings : 1,33,000 KWH
Supply frequency of Turbine generator was reduced from 50 HZ to
49.5 HZ
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Green Supply chain
Initiatives shared to Contract manufacturing units ( CMU’s)
Elimination of damper control by proving VFD for unclassified Air handling units
Energy efficient LED lights in place of Mercury vapor lamps.
Needle Type Aerators Installation for Canteen and washroom taps.
Energy Efficiency Improvement in water cooled chillers by providing on line
tube cleaning system.
Energy efficient Nitrile Rubber insulation in place of old themocoal insulation.
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SEC Reduction
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Specific Energy Consumption
21.12
20.54
19.56
18
19
20
21
22
2015 2016 2017
KW
/KG
Atorvastatin (ATT)
11.3411.14
10.4
8
9
10
11
12
13
2015 2016 2017
KW
/KG
Tenofovir (TCF)
17.817.31
16.64
12
13
14
15
16
17
18
19
2015 2016 2017
KW
/KG
Efavirenz (EFD)
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Specific Energy Consumption
Nitrogen Plant Capacity:300 Nm3/Hr
Motor : 180 HP
Chilling Plant Capacity : 200 TR
Design : + 5 ºC
Motor : 240 HP
0.57
0.49
0.4
0.45
0.5
0.55
0.6
Before VFD After VFD
KW
/NM
3
Nitrogen Plant (NT-1806)
1.05
0.81
0.3
0.4
0.5
0.6
0.7
0.8
0.9
1
1.1
1.2
With out ATCS With ATCS
KW
/TR
Chilling plant (CH-1832)
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INITIATIVES IN 2017
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Initiatives in 2017 (1/2)
Energy efficient 300 TR screw Chiller installed in place of
conventional 95 TR Chillers of 3 Nos in Utility - 9
Common Online Tube Cleaning System for 5 Chillers in
Utility - 3 & 7
Solvent vapor losses reduction by providing Online Tube
Cleaning System in SRP-2
43 This document contains confidential and proprietary information of Mylan N.V. Unauthorized use, duplication, dissemination or disclosure to third parties is strictly prohibited. © 2016 43 This document contains proprietary information of Mylan N.V. Unauthorized use, duplication, dissemination or disclosure to third parties is strictly prohibited. © 2017
Initiatives in 2017 (2/2)
Installation of Compact pressured powered pump package unit
in MB-4, 8, 9 & 10.
Introduced Energy efficient motors (IE3) of 10 Nos in place of
existing rewinding motors.
Installed 4 Nos of Parallel pumping system in Utility-1, 6, 7 & 8.
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Waste Utilization
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Utilization of waste material as fuel
Type of Residue 2014 2015 2016
Methanol MLs 2508 MT 6556 MT 3677 MT
Mixed spent solvent
1827 MT 2778 MT 2533 MT
Process Organic residue(Liquid Form)
Volatile organic solvents from Stripper 1184 MT 1423 MT 2002 MT
Process organic salts (Solid form) 110 MT 104 MT 80 MT
This Hazardous Waste is supplied to cement Industries to used as fuel in cement kiln
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RESULTS ACHIEVED
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Results Achieved
4.0
8.7 9.310.9
14.1
2013 2014 2015 2016 2017
Energy Cost Savings (in Rs. Cr)
440 495 1,350
5,584
12,297
2013 2014 2015 2016 2017
Coal Savings (in Tons)
35
31 32
31
34
2013 2014 2015 2016 2017
No. of Energy Saving Ideas Implemented
19
39 45
66 75
2013 2014 2015 2016 2017
Electrical Energy Savings (Lakh Units)
2,532 4,486 6,567
16,112
28,535
2013 2014 2015 2016 2017
Green House Gas Emissions Reduction (in Tons)
95
232 187
362
148
2013 2014 2015 2016 2017
Capital Cost (in Rs. Lakhs)
48 This document contains confidential and proprietary information of Mylan N.V. Unauthorized use, duplication, dissemination or disclosure to third parties is strictly prohibited. © 2016 48 This document contains proprietary information of Mylan N.V. Unauthorized use, duplication, dissemination or disclosure to third parties is strictly prohibited. © 2017
Future Plans
49 This document contains confidential and proprietary information of Mylan N.V. Unauthorized use, duplication, dissemination or disclosure to third parties is strictly prohibited. © 2016 49 This document contains proprietary information of Mylan N.V. Unauthorized use, duplication, dissemination or disclosure to third parties is strictly prohibited. © 2017
Future Plans
• Implementation of Online Tube cleaning system for all heat exchangers to reduce electrical Energy and Solvent vapor losses.
• Replacing Reciprocating conventional chillers with energy efficient screw chillers.
• 100 % LED lighting to be achieved in our facility.
• 8% of Total Electrical Energy Consumption reduction in next 4 Years.
• 20% Water reduction through recycling & control measures through management initiatives.
• 30% Solar power utilization targeted at site Through PPA and PV modules .
• 10% SEC reduction for TCF, VST, EFD products in next three years.
50 This document contains confidential and proprietary information of Mylan N.V. Unauthorized use, duplication, dissemination or disclosure to third parties is strictly prohibited. © 2016 50 This document contains proprietary information of Mylan N.V. Unauthorized use, duplication, dissemination or disclosure to third parties is strictly prohibited. © 2017