The Journal of Obstetrics and Gynecology of Indiajogi.co.in/sept_oct_2012/11_oa_association_of_oxidative.pdf · The Journal of Obstetrics and Gynecology of India September/October

The Journal of Obstetrics and Gynecology of IndiaOffi cial Publication of

The Federation of Obstetric & Gynecological Societies of India (FOGSI) Peer Reviewed Journal Indexed in medIND Website: www.medind.nic.in

Editors EmeritusV. N. Purandare

Mahendra N. ParikhAdi E. Dastur

Associate EditorGautam N. Allahbadia

Jt. Associate EditorC. V. Hegde

Assistant EditorSuvarna Khadilkar

Assistant SecretaryMadhuri A. Patel

Jt. Assistant SecretarySujata Dalvi

* * *Ex Offi cio Members

P. K. ShahPresident, FOGSI

Nozer SheriarSecretary General, FOGSI

H. D. PaiDy. Secretary General, FOGSI

Jaydeep TankTreasurer, FOGSI

Madhuri A. PatelJt. Treasurer

* * *

BiostatisticianArerkar Anil

Editor

C. N. Purandare

Past EditorLate K. M. Masani

Late R. D. Pandit

Founder EditorLate J. Jhirad

International Advisory Board

Arulkumaran S (UK)

Laxmi Baxi (USA)

Salim Daya (Canada)

Alan H. DeCherney (USA)

Ian Fraser (Australia)

Louis Keith (USA)

Andre Lalonde (Canada)

Kyros Nicolaides (London)

National Corresponding Editors

Subhash Biswas (Kolkata)

Asha Dalal (Mumbai)

Usha Gupta (Delhi)

Shantha Kumari (Hyderabad)

Ashok Kumar (Delhi)

Atul Munshi (Ahmedabad)

Tripti Nagaria (Raipur)

Muralidhar Pai (Manipal)

S. N. Tripathy (Cuttack)

Secretary & ManagerGeetha Balsarkar

Journal Offi ce:Model Residency CHS., Ground Floor,605 Bapurao Jagtap Marg, Jacob Circle,

Mahalaxmi East, Mumbai - 400 011.Tel: (91 22) 2302 1648, 2302 1654, 2302 1343

Fax: (91 22) 2302 1383Email: [email protected]

Website: www.jogi.co.in

The Obstetric and Gynecological Societies Affi liated to FOGSIAgartala • Agra • Ahmedabad • Ahmednagar • Aizwal • Ajmer • Akola • Aligarh • Allahabad • Alleppey • Amravati • Amritsar • Anand Asansol • Aurangabad • Azamgarh • Bangalore • Baramati • Bardhaman • Bareilly • Baroda • Beed • Belgaum • Bellary • Bengal • Berhampur • Bhagalpur • Bhandara • Bharuch • Bhavnagar • Bhagalkot • Bhilai • Bhopal • Bhubaneshwar • Bhuj • Bihar • Bijapur • Bikaner • Bilaspur • Bokaro • Bulandshahr • Burla • Calicut • Cannanore • Chalisgaon • Chandrapur • Chitradurga • Cochin • Coimbatore • Darbhanga • Davangere • Dehradun • Delhi • Deoli • Dhanbad • Dhule • Dibrugarh • Dindigul • Durg • Durgapur • Erode • Eluru • Faridabad • Firozabad • Faridkot • Gauhati • Gadhinglaj • Ghaziabad • Godhra • Gondia • Gorakhpur • Gulbarga • Guntur • Gurgaon • Gwalior • Haldwani • Hassan • Himatnagar • Hubli • Hyderabad • Ichalkaranji • Imphal • Indore • Islampur • Jabalpur • Jaipur • Jalandhar • Jalgaon • Jalna • Jammu • Jamnagar • Jamshedpur • Jhansi • Jodhpur • Jorhat • Junagadh • Kakinada • Kalyani • Kanpur • Karad • Karimnagar • Karur • Kasaragod • Kashipur • Khamam • Kerala • Kohima • Kolhapur • Korba • Kota • Kottayam • Kurnool • Latur • Loni • Lucknow • Ludhiana • Madurai • Mahabubnaga • Malda • Malegaon • Mathura • Mangalore • Manipal • Margoa • Mau • Meerut • Mehsana • Miraj • Moradabad • Mumbai • Muzaffarnagar • Muzaffarpur • Mysore • Nabha • Nadiad • Nagaon • Nagercoil • Nagpur • Nalbari • Nalgonda • Nanded • Nasik • Navi Mumbai • Navsari • Nellore • Noida • Northern Odisha • Orissa • Osmanabad • Panaji • Pandharpur • Parbhani • Patiala • Palanpur • Palghar • Porbandar • Pondicherry • Pune • Raichur • Raipur • Rajkot • Ratlam • Rajahmundry • Ranchi • Rewa • Roorkee • Rewari • Rohtak • Rourkela • Sagar • Saharanpur • Salem • Satara • Sevagram • Shillong • Shimoga • Shahjahanpur • Sindhudurgnagri • Silchar • Siliguri • Singrauli • Solapur • Southern India • Sri Ganganagar • Srinagar • Surat • Thanjavur • Theni • Thrissur • Tirunelveli • Tirupati • Trichy • Tumkur • Udaipur • Udgir • Ujjain • Varanasi • Vapi • Vellore • Visakhapatnam • Vijaywada • Warangal • Yamunanagar • Yavatmal

Disclaimer - The Editor disclaims any responsibility or liability for statements made and opinions or views expressed by authors and contributors and claims made by advertisers. Copyright - No part of this Journal can be reproduced or transmitted in any form or by any means, electronic or mechanical, without written permission from the Editor.

Printed and published by Dr. Geetha Balsarkar on behalf of The Federation Of Obstetric and Gynaecological Societies of India, Printed at Novelty Priners, AG 15/16, Saraf Kaskar Industrial Estate, Next to Union Bank, S.V. Road, Jogeshwari (West), Mumbai 400 102 and published at The Federation Of Obstetric and Gynaecological Societies of India Model Residency, 605, Bapurao Jagtap Marg, Jacob Circle, Mahalakshmi (East), Mumbai 400 011, Editor: Dr. C. N. Purandare.

Founder Secretary & ManagerLate G. N. Vazifdar

The Journal of Obstetrics and Gynecology of India September/October 2012

CONTENTS

Volume 62, No. 5, September/October 2012

EDITORIAL

MILESTONES

REVIEW ARTICLE

Contributors must meticulously follow instructions given in the Indian domestic edition

Hegde C V

Purandare C N Patel M A

Balsarkar G D

Sinai Talaulikar Vikram Belli Anna-Maria

Manyonda Isaac

Management of Large Bowel Injury During Laparoscopic Surgery

Indian Contribution to Obstetrics and Gynecology

GnRH Agonists: Do They Have a Place in the Modern Management of Fibroid Disease?

501

504

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CONTENTS


ORIGINAL ARTICLES

OBSTETRICS

Chandel Lata R Kanga Anil

Thakur KamleshMokta Kiran K Sood Anuradha Chauhan Smriti

Shalaby Hend Abdel RahamanElhady Reda Abd

Gamal Anas Mohamed Badry Ahmed Al

Balkawade Nilesh Unmesh Shinde Mangala Ashok

Prevalance of Pregnancy Associated Asymptomatic Bacteriuria: A Study Done in a Tertiary Care Hospital

Pregnancy associated asymptomatic bacteriuria is a common occurrence. In the present study incidence came out to be 7.34%. The commonest pathogen isolated was E.coli amounting to 79.5%. Because of complications associated with asymptomatic bacteriuria in pregnancy, it should be diagnosed early and should be treated with appropriate antibiotic therapy. Culture of urine sample is the gold standard method for diagnosis.

Prenatal Diagnosis in Low Resource Setting: Is It Acceptable?

This study reveals attitude and acceptability of prenatal procedures among Egyptian women. Positive attitude was expressed towards non-invasive procedures. Attitude was guarded towards invasive procedures due to fear of abortion. Cost of procedure did affect the decision.

Study of Length of Umbilical Cord and Fetal Outcome: A Study of 1,000 Deliveries

The present study was undertaken to assess the correlation between umbilical cord length and fetal outcome. The fi ndings of a worrisome fetal heart rate tracing or failure of fetal descent during labor is not uncommon. Most of these are associated with abnormalities of cord length.

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CONTENTS


ORIGINAL ARTICLES

OBSTETRICS

Patil Mithil M

Nkwabong Elie Fomulu Joseph Nelson

Kouam Luc Ngassa Pius Chanchu

Hansda Jayasree Roychowdhury Joydeb

Role of Neuroimaging in Patients with Atypical Eclampsia

Eclampsia is associated with increased risk of maternal mortality from 1.8% in developed countries to 14% in developing countries. We have done neuroimaging with CT scan in 30 eclampsia patients who do not respond to the routine treatment ie. MgSO4 and antihypertensives. In almost 20 patients we have found cerebral oedema described as Posterior Reversible Encephalopathy Syndrome & in 4 patients cerebral infarction. CVTS is found in 2 patients and tuberculomas in another two. Most of these patients who were refractory to the conventional treatment, responded to the medical management such as IV. Mannitol in Oedema and antiKochs treatment in tuberculomas.

Outcome of Breech Deliveries in Cameroonian Nulliparous Women

Vaginal breech delivery is unsafe in some, but not all, nulliparous women.

Study of Thrombophilia in Recurrent Pregnancy Loss

There is defi nite association between thrombophilic defect and recurrent pregnancy loss, preterm births and IUGR due to placental vasculopathy. Even after thorough evaluation in one third of cases, cause remains uncertain. Large and long term studies are necessary to prove stronger association to initiate early antithrombotic therapy.

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531

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CONTENTS


Batra SoniaNayak Himanshu

Dave Kalpana S

Mahanta R Gogoi A Chaudhury P N B Roy S

Bhattacharyya I K Sharma P

Sangeeta Shah

Role of Neoadjuvant Chemotherapy (NACT) Followed by Surgical Cytoreduction in Advanced Epithelial Ovarian Cancer

This study was conducted to demonstrate the role of Neoadjuvant chemotherapy(NACT) in advanced epithelial ovarian cancer. It also demonstrates pattern of presentation and socio-demographic characteristics of advanced ovarian cancer.

Association of Oxidative Stress Biomarkers and Antioxidant Enzymatic Activity in Male Infertility of North-East India

The aimed study for fi nding the association of oxidative stress biomarkers; the Lipid and Protein peroxidation and antioxidant enzymes as Superoxide dismutase and Glutathione peroxidase activity in male infertility showed positive correlation between the stress biomarkers and antioxidant enzyme activity in the studied population of normozoospermic and infertile group.

Metformin and Pioglitazone in Polycystic Ovarian Syndrome: A Comparative Study

Pioglitazone may be a newer alternative insulin-sensitizing drug to metformin, in the treatment of PCOD, as it has more metabolic and reproductive benefi ts and may also act in the long term to protect these women from developing Type-II diabetes mellitus. However unlike metformin it cannot be used if the woman conceives during treatment.

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551

ORIGINAL ARTICLES

GYNECOLOGY



CONTENTS


Madhumati Goel Kavita Somani

Anju Mehrotra Uma Singh Raj Mehrotra

Patidar Arvind Kumar Kumar H S

Walke Rahul VHirapara Pushpendra H

Jakhar Shankar Lal Bardia M R

Immunohistochemical Expression of Cell Proliferating Nuclear Antigen (PCNA) and p53 Protein in Cervical Cancer

The results of the present study observed that specifi c biomarkers of dysplasia (p53 & PCNA) could greatly improve the accuracy, precision, and sensitivity of cervical screening programs. These biomarkers will be helpful in those cases, which are seen low grade in histology sections but have a high proliferative index.

Evaluation of the Response of Concurrent High Dose Rate Intracavitary Brachytherapy with External Beam Radiotherapy in Management of Early Stage Carcinoma Cervix

To evaluate local disease control and early complications, we compare concomitant with sequential brachytherapy in early stage carcinoma cervix. Response was better in the study group but statistically insignifi cant at cost of increased but manageable acute reactions. Larger study and longer follow up is advised to arrive at concrete conclusion.

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ORIGINAL ARTICLES

GYNECOLOGY



CONTENTS


Manisha Meena Jyoti Singh Abha

Singh Anuradha

Gupta Rakhi Tickoo Girija

Culha Cavit Ozkaya Mesut

Serter Rustu Sahin Ibrahim Aydin Bayram

Aral Yalcin

Majumdar Abha Gill Kavneet

A Rare Case of Vaginal Delivery After Uterine Rupture

Persistent Uterine Prolapse During Pregnancy and Labour

Swyer’s Syndrome: In a Fifty-Year-Old Female

Severe Adolescent Menorrhagia Due to Cervical Fibroid

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568

571

575

CASE REPORTS

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The Journal of Obstetrics and Gynecology of Indiajogi.co.in/sept_oct_2012/11_oa_association_of_oxidative.pdf · The Journal of Obstetrics and Gynecology of India September/October