The Effect of Tai Chi on 24 4 59

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     The Efect O Tai Chi onMild Alzheimer’s patients

    ประสทธผลของไทช ในผ  ป วยอลไซเมอรระดบตน

    Miss Chomlak Kongart

    Student ID: 5779051153

    For qualifying examination (QE)

    1

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      Background and Rational

    • In Thailand, the percentage of young andworking age population will continue todecline from 2010 to 2040, while the numberof elderly population continues to increase, from 13.2 percent in 2010 and is estimated to be32.1 percent in 2040 !nodel et al., 201"#.

    • The characteristic of elderly had manyunderlying disease $ diabetes, hypertension

    and dementia.• In Thailand, the pre%alence of dementia is

    22&,000 in 200" and it is e'pected 4"2,000 in2020 and 1,233,000 in 20(0 )*I )sia +asificand non)*I )sia +acific#.

    2

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    • Increasing prevalence o dementia has a badpotential impact or status and the public healthsystem o a country This is because dementia disease can be possible side efects! such as social and economic burden or the amily

    • "p to no#! medications have not yet beensho#n efective in stopping this particulardisease! and some have problematic side efects $ut some practices! li%e regular e&ercise! have sho#n progress in delaying the advance o Alzheimer's disease

    3

      Background and

    Rational

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    • According to (ancheva et al )*++,-

    that up to .+ percent o people #ith

    Alzheimer’s also have symptoms o  depression and an&iety /ue to dementia people may eventually #ithdra# rom all activities and di0culty to balance themsel in all activities

    4

      Background and Rational

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    •  The physical activity such as Tai Chi could improvethe balance and prevent elderly on the rail problem such as ris% to all

    • Many studies have suggested that tai chi can help

    boost older adults’ immunity to viruses andimprove their balance! thereby helping to prevent  alls )1i! 2! 3armer! 4! 2itzgerald! 5 et al! *++6-

    •  Tai chi can help improve physical condition! muscle

    strength! coordination! and 7e&ibility8 ease painand stifness8 reduce depression and an&iety! improve sleep and balance )1i! 3armer! 9 2isher! *++6-

    5

      Background and Rational

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      Gap of Knowledge

    • Many studies have sho#n that Tai Chi has bene:cialefects on balance! alls! and non;vertebralractures! depression and an&iety but in Thailand doesn't have study yet

    Many studies have investigated methods to preventdementia symptoms! but e# have investigated theefect o Tai Chi on dementia patient

    • Importantly the evaluation o the health status odementia in this study implemented three methods!

    namely 3am;/! 3am;A and berg $alance slcae )$$<- #hich are still rare to be used simultaneously to evaluate the efect o Tai;chi to#ard the cognitive improvement o the mild Alzheimer patients

    6

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     =esearch >uestion

    • Does Tai Chi intervention treatment is able to

    reduce Anxiety, Depression and improveBalance for Mild AD.?

    7

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     =esearch Ob?ectives

    General Objective

    • To study effectiveness of Tai Chi practice model on

    anxiety, depression and balance in mild Alzheimers

     patients

    Specific Objectives

    • To measure Anxiety, Depression and Balance before

    and after experiment of control and trial !roups.

    • To compare Anxiety, Depression and Balance

     bet"een control and trial !roups before and after

    experiment.

    8

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     =esearch 3ypothesis

    The Taichi practice significantly affects to

    ameliorate the )n'iety, *epression and

    -alance after e'periment.

    • There is significant different an'iety score ,*epression score ,-alance score between

    inter%ention and control group after Tai chi pr 

    actice. ttest#

    • Taichi practice affects significantly to

    ameliorate the )n'iety, *epression and

    -alance on trail group after Tai chi program.

    pair ttest#

    9

    9

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     Conceptual Framework 

    10

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     Literature e!ie"

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     1iterature =evie#

     Alzheimer’s disease can be divided in tothree phases

    Mild;

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     1iterature =evie#

     AD detection4ositron emission tomography )4ET-!

    Computed tomography )CT- and

    Magnetic resonance imaging )M=I-scans

    Alzheimer’s disease afects on 

    A loss o cognitive unctioning

    /epression! an&iety andbalance

    13

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     1iterature =evie#

    Tai chi Tai;Chi is derived rom traditional

    Chinese martial arts

     Tai;Chi practice breathing and rela&ingbody movement slo# and smoothrhythm o movement Its practice is associated #ith a lo# metabolic load and si

    gni:cant psychological bene:t and @uality o lie )Chen! *+*-

    14

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    Tai Chi and Al Zheimer

    Sno"den et al#$ %011

    &h'si(al a(ti!it' or e)er(ise *tai+(hi,im&ro!ed (ognition in older adults

    C# -ang$ Collet$ .Lau$ %004,

    egular tai (hi e)er(ise ma' hel& "ith&reser!ation o/ gloal ailit' in elders at

    risk o/ (ogniti!e de(liner'e$ S(heinthal$ Kemarska'a$ . 2ru(hno$ %007

    tai (hi are sa/e$ (ost+ee(ti!e "a's toim&ro!e oth &h'si(al and &s'(hologi(al/un(tioning o/ older &eo&le

    -ol/$ arnhart$ llison$ 

    Coogler$ . 6tlanta ICSI$ 1997,

     ai Chi has een (hara(teri8ed as mind+od' inter!entions and as meditati!e

    mo!ements

    Kasai et al#$ %010 6/ter si) months o/ inter!ention$ the CC rou&sho"ed signi;(ant im&ro!ement on theeha!ioral Memor' est and Memor'Com&laint S(ale

    15

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    Measuring health statusfor mild Alzeimer case

    • amilton Rating !cale for"epression #am$"%

    • amilton An&iet' Rating!cale #AM$A%

    • Berg(s Balance !cale #BB!%

    1<

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      esear(h Methodolog'

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    • This is an pre#experimental research study, t"o !roups,

     pre#test # post#test desi!n.

    18

      esear(h Design

    $ % $xperimental

    !roup

    C % Control !roup

    &' % (re#studymeasurement

    &) % (ost *study

    measurement

    + % Tai # chi

    =1

    =1

    C

    =%

    =%

    >

    ollo" u& 1% "eeks

    ollo" u& 1% "eeks

    ollo" u& %4 "eeks

    ollo" u& %4 "eeks

    >

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    •  The target population o this study #as a participant

    #ho had been ormally diagnosed #ith mild Alzheimer

    stage and treated in 5ing Chulalong%orn 3ospital 

    )nclusion criteria – 4atients #ho diagnosed o mild Alzheimer stage B+ years old

    and over

     – oluntariness to participate in this study

     – Able to spea% and understand Thai #ith no severe hearing

    impairment

    • *&clusion criteria

     – =egular practice o Tai;Chi

     – 4atients #ho #ere un#illing or unable to participate

     – Emergence o ne#er symptom

     – older people #ith blindness8

      2o&ulation and sam&le si8e

    19

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      2o&ulation and sam&le si8e

    20

    ampel size "as calculatin! by implementin!

    -#(o"er application. The result as follo"

    $ffect desi!n /d0 123 /4ee,et.al )2250Alpha error 2.26

    (o"er /'#70 2.56

    $xperimental !roup 8)

    Control !roup 8)

    Total sample 18

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    • the D participants #ere randomly byusing the e&cel program rom all adpatient

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    3amilton an&iety ratting scale)3AM;A-

    3amilton depression scale)3AM;/-

    $erg balance scale )$$

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    3amilton depression scale)3AM;A-

    •  The scale designed to assess theseverity o a patient’s an&iety Eacho the items contains a number o sy

    mptoms and each group o symptoms is rated on a scale o zero to our! #ith our being the most severe

    a

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     The @uestionnaire is designed or adults andis used to rate the severity o theirdepression byG 4robing mood! 2eelings o guilt!

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     The $erg $alance

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    &uestionnaires "ill examine in the part of

    reliability and validity in all of by nurse and

    9uestionnaires test before use in the pro:ect.An alternative /meditation0 therapy manuals "ill

    examine for reliability and validity by expert

    and trial out before use in the pro:ect.

     @alidate o/ resear(h tools

    26

    i hi i

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     The intervention group undertoo% a Tai;Chipractice protocol! #hile a control groupreceived usual care

    •  The TC sessions #ill involve group practice#ith instruction given in both verbal andvisual orm to demonstrate both the movements and the basic theory behind each action

    • Each TC session #ill consist o 6 minutes o

    #arm up! *6 minutes o TC practice and +minutes o cooling do#n The TC #ill be ledby a s%illed instructor #ho has been practicing TC and have TC instructor certi:cate

    ai+(hi Inter!ention

    27

    i hi I i

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    •  TC sessions #ill ta%e place during * #ee%s#hich contact #ith instructor

    •  T#o time per #ee% and + min per time

    )#arm;up! tai;chi practice and cool do#n-

    ai A (hi Inter!ention

    28

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    Data Colle(tion

    29

    aseline data /or all &arti(i&ants "as(olle(ted ' the resear(her and theresear(h assistant em&lo':• the ?amilton rating s(ale /or an)iet'

    *?6M+6,$• ?amilton rating s(ale /or de&ression

    *?6M+D,$•

    erg alan(e s(ale *S, instrument#• But(ome assessment data "as

    (olle(ted at "eek e/ore 1%"eek$ a/ter1% "eek and a/ter %4 "eek#

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      Data 6nal'sis

    30

    • (ersonal data , ;amA, ;amD and BB score

    "ere analysis by descriptive statistics in

    fre9uency, percenta!e, mean and standard devi

    ation• Compare personal data and symptom of

    anxiety, depression and balance score "ill be

    analyzed by Chi#s9uare test, fishers exact test.• To compare the different bet"een experiment#

    control and before and after, the student t#test

    "ill be applied

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    •  To compare the diferent bet#eenbeore and ater apply tai;chiprogram in e&periment group by

     using pair t;test

    31

      /ata Analysis

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    • 2or ethical consideration! the proposal #illbe submitted or approval rom Jolden

     Kubilee Medical Center! Mahidol "niversity

    4articipants #ill receive both #ritten andverbal inormation beore they agreed toparticipate

    • Inormed signed consent

    •  They have to right to reuse to participate inthe study

    • 3ave reedom to #ithdra#al

    •  Their inormation #ill be %ept con:dentially!and not used or other purpose

    thi(al Consideration

    32

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    • /ue to the limitation o the research

    coverage! this study potential to produce a selection biases because this selection  ocused on only patient #ho treated at the5ing Chulalong%orn 3ospital.

      Limitation

    33

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    • 2irstly! the result o this study may helpincreasing the #ell;being those #ho has aproblem to the Alzheimer’s This study endeavor to bene:t elderly persons and eldersL  amilies! community! and anyone #ho has interested in the topic

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    35

      esear(h s(hedule

    Activities

    Months

    1 % 3 4 5 < 7

    Elaborate proposal and literature

    review

     

    Explore site visit for Alheimer  

    !ool development and approval fromEthical committee

     

    !rial out technique and intervention

    study in mild Alheimer"s patients

     

    #ata collection

    #ata analysis

    $riting research paper and publication

    d t

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    #escription  !otal Amount (%aht)

    1#ata &ollection and processing 

    Communi(ation *ele&hone$ a)$ Internet, 10$000

    Stationar' *&a&er$ toner$, 10$000

    Lo(al rans&ortation Costs *a)i$ (ar rent$

    messenger,

    10$000

      'ubtotal *+***

    % Field survey and Questionnaires ,aunching 

    Instrument and Eui&ment 30$000

    uel and other e)&enses 3$000

      'ubtotal -+***

    3 Expertise &onsultation 

    =uestionnaires !alidit' and reliailit' 15$000

      'ubtotal ./+***

    4 0roductions 

    e&ort *2ro&osal$ 2rogress and Com&lete &a&er, 1000

    6rt "ork$ (o!er &age 3$000  'ubtotal 1+***

      udget

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     T3A5 (O"2O= (O"= ATTETIO