Master Distributor for Canada Central Sales Limited

Toll free 1-800- 387-2522

AVAILABLE NOW in 10 mL and 20 mL vials through Central and Pacific Vet Sales.

Distributor Partner Pacific Veterinary Sales

Toll free 1-800-663-6966

New

® Registered Trademark of Jurox Pty Ltd

The consistency and confidence you have developed with Alfaxan now comes in a multidose vial.

Preserved formulation allows for 28 day shelf-life after broaching

Repeatable and reliable anesthesia provides for smooth inductions

Helps maintain clinically acceptable cardiovascular and respiratory parameters

Rapid clearance and recovery

Alfaxalone Injection 10 mg/mL

day shelf life after broaching

www.jurox.ca

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CSL Code VP CDMV DESCRIPTION LIST PRICE424-520415 1401310 126169 Alfaxan Multidose 10 mL $43.56424-520425 1401315 126452 Alfaxan Multidose 20 mL $85.00

AVAILABLE NOW in BOTH 10 mL and 20 mL vials!

Alfaxan Multidose is the new, preserved formulation of alfaxalone, combining the reliability you have come to expect from Alfaxan, with the versatility that comes with an extended shelf life of 28 days after first opening.

Helps maintain clinically acceptable cardiovascular and respiratory parameters

Versatility from healthy to special populations to compromised patients. (ASA I-V1, C-Sections2, sighthounds3, brachycephalic4, juvenile cat and dogs5)

Compatible with commonly used premedicant, maintenance and analgesic protocols

USE WITH CONFIDENCESAFETY MARGIN

BIOEQUIVALENCE ALFAXAN VS ALFAXAN MULTIDOSE

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Plasma alfaxalone concentration vs time in dogs treated with Alfaxan or Alfaxan Multidose

at 3 mg/kg (n=24 per group).

Plasma alfaxalone concentration vs time in cats treated with Alfaxan or Alfaxan Multidose

at 5 mg/kg (n=24 per group).

day shelf life after broaching

ADMINISTER OVER

SECONDS

References:(Graphs) Jurox GLP study JX9604.08-L026 – An in vivo study investigating the bioequivalence of Alfaxan® versus alfaxalone plus preservatives as an injectable anesthetic agent in dogs.Paslosk K et al. The bioequivalence of a single intravenous administration of the anesthetic alfaxalone in cyclodextrin versus alfaxalone in cyclodextrin plus preservatives in cats. J Vet Pharmacol Ther 2018 Jan 19. doi: 10. 1111/jvp.12485 [Epub ahead of print].

1. Psatha E, et al., Clinical efficacy and cardiorespiratory effects of alfaxalone, or diazepam/fentanyl for induction of anaesthesia in dogs that are a poor anaesthetic risk. Vet Anaesth Analg, 2011, 38: p. 24-36.2. Metcalfe, S. et al., Multicentre, randomised clinical trial evaluating the efficacy and safety of alfaxalone administered to bitches for induction of anaesthesia prior to caesarean section. Aust Vet Journal, Vol. 92, No 9, Sept 2014: p. 333-338.3. Pasloske, K., et al., Plasma pharmacokinetics of alfaxalone in both premedicated and unpremedicated Greyhound dogs after single, intravenous administration of Alfaxan at a clinical dose. J. vet. Pharmacol. Therap. 32, 510–5134. Jurox report., JX9604.03-C009 (GCP), Dog Field Trial5. O’Hagan, B., et al., Clinical evaluation of alfaxalone as an anaesthetic induction agent in dogs less than 12 weeks of age. Aust. vet, Journal, 2012.,90(9): p. 346-50.

O’Hagan, B., et al., Clinical evaluation of alfaxalone as an anaesthetic induction agent in cats less than 12 weeks of age. Aust. vet, Journal, 2012.,90(10): p. 395-401

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® Registered Trademark of Jurox Pty Ltd

Master Distributor for Canada Central Sales Limited Toll free 1-800- 387-2522

Distributor Partner Pacific Veterinary Sales Toll free 1-800-663-6966

www.jurox.ca