-
7/31/2019 The Chemistry Behind the Adverts
1/14
THE SCIENCE BEHIND THE ADVERTS
-
7/31/2019 The Chemistry Behind the Adverts
2/14
FLEAS, TICKS, TAPEWORMS, AND
LYME DISEASE
So, naturalists observe, a flea has smaller fleas thon him prey;
and these have smaller still to bite eand so proceed ad
infinitum."- Jonathan Swift
-
7/31/2019 The Chemistry Behind the Adverts
3/14
-
7/31/2019 The Chemistry Behind the Adverts
4/14
PRAZIQUANTEL
Retail price per tab: $1.60 - $6.00 depending on br
The current cost of a 600 mg tablet at a
mere US $0.072 www.stanford.edu
Action: Following exposure to praziquantthe tapeworm loses its
ability to resist digby the mammalian host. Bayer site.
-
7/31/2019 The Chemistry Behind the Adverts
5/14
SEARCH FOR A WORM-KILLER
Bayer began an intensive program to develop a worm-killer
(antihelminthic drug). Early on, researchers investigated
severalnaturally occurring compounds extracted from plants..
Ascaridole was one of these compounds. It is found in wormseed
oil whichis extracted from the plant, Chenopodium ambrosiodes,
native to theAmericas.
Ethnobotany is the scientific study of therelationships that
exist between people
and plants.
Ascaridole structure
Praziquantel, proved to me a more effectiantihelminthic
drug.
-
7/31/2019 The Chemistry Behind the Adverts
6/14
Neurocysticercosis (NCC) is the most common parasitic disease of
the
nervous system and is the main cause of acquired epilepsy
indeveloping (developed) countries.
Neurocysticercosis can be acquired via fecal-oralwith carriers
of the adult tapeworm Taenia solium.This usually indicates the
presence of a tapewormin the immediate environment (ie,
household)or by accidental ingestion of contaminated
food.Neurocysticercosis can be treated with Praziquantcaught in the
early stages of infection.
-
7/31/2019 The Chemistry Behind the Adverts
7/14
Dipylidiumis tapeworm of cats and dogs. People become infected
when taccidentally swallow a flea infected with tapeworm larvae;
most reporteinvolve children. Dipylidiuminfection is easily treated
in humans and aniOnce hatched, the larvae will grow into hydatid
cyst in the liver and othersurrounding organs. The cysts will
continue to grow to as much as a fooand in most cases will need to
be surgically removed.
Read more: How Do Humans Get Tapeworms From Dogs? |- - - -
Zoonotic tapeworms are tapeworms that live in animals but can be
transto humans.
http://www.ehow.com/how-does_5164980_do-humans-tapeworms-dogs.htmlhttp://www.ehow.com/how-does_5164980_do-humans-tapeworms-dogs.htmlhttp://www.ehow.com/how-does_5164980_do-humans-tapeworms-dogs.htmlhttp://www.ehow.com/how-does_5164980_do-humans-tapeworms-dogs.htmlhttp://www.ehow.com/how-does_5164980_do-humans-tapeworms-dogs.htmlhttp://www.ehow.com/how-does_5164980_do-humans-tapeworms-dogs.htmlhttp://www.ehow.com/how-does_5164980_do-humans-tapeworms-dogs.htmlhttp://www.ehow.com/how-does_5164980_do-humans-tapeworms-dogs.htmlhttp://www.ehow.com/how-does_5164980_do-humans-tapeworms-dogs.htmlhttp://www.ehow.com/how-does_5164980_do-humans-tapeworms-dogs.htmlhttp://www.ehow.com/how-does_5164980_do-humans-tapeworms-dogs.htmlhttp://www.ehow.com/how-does_5164980_do-humans-tapeworms-dogs.htmlhttp://www.ehow.com/how-does_5164980_do-humans-tapeworms-dogs.htmlhttp://www.ehow.com/how-does_5164980_do-humans-tapeworms-dogs.htmlhttp://www.ehow.com/how-does_5164980_do-humans-tapeworms-dogs.htmlhttp://www.ehow.com/how-does_5164980_do-humans-tapeworms-dogs.htmlhttp://www.cdc.gov/parasites/dipylidium/index.htmlhttp://www.cdc.gov/parasites/dipylidium/index.htmlhttp://www.cdc.gov/parasites/dipylidium/index.htmlhttp://www.cdc.gov/parasites/dipylidium/index.html
-
7/31/2019 The Chemistry Behind the Adverts
8/14
FROM YOUTUBE
Ouch!
Brain
http://www.youtube.com/watch?v=AgsU5h24BMA
Eye
http://www.youtube.com/watch?v=-dJ7wdBYZs4&feature=fvwp&NR=1
Lungs and Liver
http://www.youtube.com/watch?v=iktGGMHH1Hg
.
http://www.youtube.com/watch?v=AgsU5h24BMAhttp://www.youtube.com/watch?v=AgsU5h24BMAhttp://www.youtube.com/watch?v=-dJ7wdBYZs4&feature=fvwp&NR=1http://www.youtube.com/watch?v=iktGGMHH1Hghttp://www.youtube.com/watch?v=iktGGMHH1Hghttp://www.youtube.com/watch?v=-dJ7wdBYZs4&feature=fvwp&NR=1http://www.youtube.com/watch?v=-dJ7wdBYZs4&feature=fvwp&NR=1http://www.youtube.com/watch?v=-dJ7wdBYZs4&feature=fvwp&NR=1http://www.youtube.com/watch?v=AgsU5h24BMAhttp://www.youtube.com/watch?v=AgsU5h24BMAhttp://www.youtube.com/watch?v=AgsU5h24BMAhttp://www.youtube.com/watch?v=AgsU5h24BMAhttp://www.youtube.com/watch?v=AgsU5h24BMA
-
7/31/2019 The Chemistry Behind the Adverts
9/14
THE FLEA PROBLEM
The active ingredient in Advantage is imidacloIt makes up 9.1%
of the solution. Imidacloprid iinsecticide made from nicotine. This
compounextracted from the plant, Nicotiana, tobacco.
Neighborhoods where many owners use theproduct may find, that
over time, the fleapopulation evolves to be come resistant to
tproduct! Then you have to try another formu
To see if you get results!
Advantage and Advantage II dont control ti
Ticks can transmit Lyme disease to you or y
http://www.npic.orst.edu/factsheets/imidacloprid.pdf
-
7/31/2019 The Chemistry Behind the Adverts
10/14
SO HOW DO YOU MANAGE THE TICKS?
Add a pyrethrin to the formula. These kill ticks and also mites.
Pyrethrins
are natural extracts made from flowers of chrysanthemum
plants.
Ticks can transmit Lyme disease to you or your pet.
Pyrethrum (Chrysanthemumcinerariaefolium)
-
7/31/2019 The Chemistry Behind the Adverts
11/14
ENVIRONMENTAL PROBLEM
Use of Common Pesticide, Imidacloprid, Linked to Bee Colony
Collapse
ScienceDaily(Apr. 5, 2012) The likely culprit in sharp
worldwidedeclines in honeybee colonies since 2006 is imidacloprid,
one of themost widely used pesticides, according to a new study
from HarvardSchool of Public Health (HSPH).
Nicotine and nicotine derivatives, are insect neurotoxins.
-
7/31/2019 The Chemistry Behind the Adverts
12/14
Honeybee on knapweed. The likely culprit in sworldwide declines
in honeybee colonies since2006 isimidacloprid, one of the most
widely upesticides (Credit: Elenathewise / Fotolia)
Imidacloprid structural formula
-
7/31/2019 The Chemistry Behind the Adverts
13/14
WE ARE ALL CONNECTED
Fleas, tapeworms, dogs, cats, humans, pigs, tobacco and
chrysanthemum plants,honey bees, ticks, Borrelia burgdorferi(Lyme
Disease bacterium), and.
Many diseases can be viewed as environmental problems. That may
requireecological approach to control.
-
7/31/2019 The Chemistry Behind the Adverts
14/14
NEW TERMS
praziquantel
ethnobotany
antihelminthic drug
Neurocysticercosis(NCC)
zoonotichydatid cyst
pyrethrins
Bee Colony Collapse
neurotoxins.
ascaridole
wormseed oil
imidacloprid
Nicotiana
Chrysanthemum
