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THE CHEMICAL CONSTITUENTS OF THE ETHYL
ACETATE EXTRACT OF THE STEMS OF POLYALTHIA
BULLATA
MOHD AFIF BIN WASIS
Final Year Project Report Submitted in Partial Fulfillment of the Requirements for the
Degree of Bachelor of Science (Hons.) Applied Chemistry in the Faculty of Applied Sciences
Universiti Teknologi MARA
NOVEMBER 2008
This Final Year Project Report entitled "THE CHEMICAL CONSTITUENTS OF THE ETHYL ACETATE EXTRACT OF THE STEMS OF POLYALTHIA BULLATA" was submitted by Mohd Afif Bin Wasis, in partial fulfillment of the requirements for the Degree of Bachelor of Science (Hons.) Applied Chemistry, in the Faculty of Applied Sciences, and was approved by
Puan Faridahanim Binti Mohd Jaafar Supervisor
B. Sc. (Hons.) Applied Chemistry Faculty of Applied Sciences Universiti Teknologi MARA
40450 Shah Alam Selangor
Miss Sabnna ointi M. Yahaya Project Coordinator
B.Sc (Hons) Applied Chemistry Faculty of Applied Sciences Universiti Teknologi MARA
Dr. Yusairie Head of Programme
B.Sc. (Hons) Applied Chemistry Faculty of Applied Sciences Universiti Teknologi MARA
Date lll*lo*
ACKNOWLEDGEMENTS
First of all, I would like to express my gratitude and appreciation to my
supervisor, Puan Faridahanim Mohd Jaafar, for his advice, valuable guidance,
inspiring suggestions, and motivation during the hard time for accomplished of
this Final Year Project. Subsequently, I would like to thank all the postgraduate
students of natural product studies who have always supported and helped me
in completing my project successfully. My heartiest thanks and appreciation are
for my parents, Encik Wasis Bin Kasan and Rokiah Binti Mohd Johan for their
never ending support. To all my friends who have been very helpful, I will
remember every moment that has been shared together. Last but not least,
thank to all laboratory assistants for their helped and supported me until I
finished this project
iii
TABLE OF CONTENTS
Page
ACKNOWLEDGEMENT iii TABLE OF CONTENTS iv LIST OF TABLE iv LIST OF FIGURE v LIST OF ABREVATIONS ABSTRACT ABSTRAK
CHAPTER 1 INTRODUCTION 1
CHAPTER 2 LITERATURE REVIEW
2.1 Introduction 4
2.2 Plant Morphology
2.2.1 Annonaceae 5
2.2.2 Polyalthia 7
2.2.3 Polyalthia bullata 7
2.3 Traditional Uses
2.3.1 Polyalthia 8
2.3.2 Polyalthia bullata 8
2.4 Biological Activities
2.4.1 Polyalthia 9
2.5 Medicinal Values
ABSTRACT
THE CHEMICAL CONSTITUENTS OF THE ETHYL ACETATE EXTRACT OF THE STEMS OF POLYALTHIA BULLATA
Polyalthia Bullata is a plant that is traditionally effective as an aphrodisiac for men. In Malaysia, this plant is known as Tongkat Ali Hitam or Tongkat Ali Baginda. The stem bark of Polyalthia Bullata underwent successive solvent extraction using hexane, dichloromethane, ethyl acetate and methanol. The crude ethyl acetate extract was subjected to column and thin layer chromatography. Phytochemical analysis on the stem bark of Polyalthia Bullata yielded the known aporphine isoquinoline alkaloid, liriodenine. The compound was identified by UV, IR, GC-MS and NMR and compare with the literature. The weight and % yield of the compound were 3.8 mg and 0.4524 % respectively
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