Division of CardiologyDepartment of MedicineUniversity of CaliforniaSan Francisco, School of Medicine

University of CaliforniaSan Francisco

THE CALIFORNIA HEARTRHYTHM SYMPOSIUM

JW Marriott Hotel San Francisco

UCLA CARDIAC ARRHYTHMIA CENTER

University of CaliforniaSan Francisco

FRIDAY-SATURDAY

September 7-8, 2012

Edward P. Gerstenfeld, MDGregory M. Marcus, MS, MASZian H. Tseng, MD, MASKalyanam Shivkumar, MD, PhDGregory K. Feld, MD

CALL FOR ABSTRACTSAbstract Submission Deadline:June 30, 2012For details and submissions,please visit the conferencewebsite at www.cme.ucsf.edu

THE CALIFORNIAHEART RHYTHMSYMPOSIUM

The California Heart Rhythm Symposium aims to bring together leaders and emerging leadersin cardiac electrophysiology in the world today.The primary purpose of this conference is tohighlight what is known about basic arrhythmiamechanisms, how our clinical therapeuticstrategies are driven by science, and howobservations from clinical therapeutics havecreated new avenues for research.

TARGET AUDIENCE

This meeting will benefit practicing andacademic electrophysiologists, electrophysiologyfellows in training, general cardiologists, andallied health professionals who have an interestin learning how the specialty of cardiacelectrophysiology is evolving, from the peoplewho are at the forefront of that evolution.

OBJECTIVESUpon completion of this activity participants will be betterable to:• Recognize the latest advances in the methods andindications for: ablation of junctional tachycardias,ablation of paroxysmal and persistent atrial fibrillation,and ablation of ventricular tachycardia;

• Enhance knowledge of sudden death risk stratification in athletes and congenital heart disease patients;

• Improve understanding of the mechanism, epidemiologyand treatment of early repolarization syndrome;

• Enhance knowledge of appropriate use of the novel oral anticoagulants;

• Summarize how these advances are translated into new therapies;

• Apply these treatment advances to their own clinicalpractice.

JW Marriott Hotel San Francisco, CA

September 7-8, 2012

CALL FOR ABSTRACTS:Deadline for Submission of Abstracts:June 30, 2012Please visit our website: http://cme.ucsf.edu for abstractsubmission instructions. Abstracts will be chosen for poster presentation andpresenters will be guests of the symposium.

ACCREDITATION

The University of California,San Francisco School of Medicine (UCSF) is accredited by theAccreditation Council for Continuing MedicalEducation to providecontinuing medicaleducation for physicians.

UCSF designates this liveactivity for a maximum of16.5 AMA PRA Category 1Credit/sTM. Physiciansshould only claim creditcommensurate with theextent of their participationin the activity.

This CME activity meets the requirements underCalifornia Assembly Bill 1195, continuingeducation and cultural andlinguistic competency.

Nurses:For the purpose ofrecertification, the AmericanNurses CredentialingCenter accepts AMA PRACategory 1 Credit™ issuedby organizations accreditedby the ACCME.

Pharmacists:The California Board of Pharmacy accepts ascontinuing professionaleducation those coursesthat meet the standard ofrelevance to pharmacypractice and have beenapproved for AMA PRACategory 1 Credit™.

COURSE CO-CHAIRS

Edward P. Gerstenfeld, MDAssociate Professor of MedicineChief, Cardiac Electrophysiologyand Arrhythmia ServiceUniversity of California,San FranciscoSan Francisco, CA, USA

Gregory M. Marcus, MD, MASAssistant Professor of Medicine,Division of Cardiology,Electrophysiology SectionUniversity of California, San FranciscoSan Francisco, CA, USA

Zian H. Tseng, MD, MASAssociate Professor of MedicineUniversity of California, San FranciscoSan Francisco, CA, USA

Gregory K. Feld, MDProfessor of MedicineDirector, EP ProgramUniversity of California, San DiegoSan Diego, CA, USA

Kalyanam Shivkumar, MD, PhDProfessor of Medicine andRadiological Sciences; Director,UCLA Cardiac Arrhythmia Center,David Geffen School of Medicine at UCLA, Los Angeles, CA, USA

GUEST FACULTYCharles Antzelevitch, PhDExecutive Director and Director of Research, Masonic MedicalResearch LaboratoryUtica, NY, USA

Samuel J. Asirvatham, MDProfessor of Medicine andPediatrics, Mayo Clinic Rochester, MN, USA

Andre d’Avila, MD, PhDAssociate Professor of MedicineCo-Director, Helmsley ArrhythmiaService, Mount Sinai Hospital and School of MedicineNew York, NY, USA

Timm-Michael Dickfeld, MD, PhDAssociate Professor of MedicineUniversity of Maryland, School ofMedicine; Chief,Electrophysiology, Baltimore VAMedical CenterBaltimore, MD, USA

Sanjay Dixit, MDDirector, Cardiac EP, PhiladelphiaVA Medical Center; AssociateProfessor, University ofPennsylvania School of Medicine,Philadelphia, PA, USA

J. Kevin Donahue, MDAssociate Professor, Departmentof Physiology and BiophysicsCase Western Reserve UniversitySchool of MedicineCleveland, OH, USA

GUEST FACULTY (CONT’D)Susan J. Eisenberg, MDArrhythmia Specialists Inc.Walnut Creek, CA, USA

Michael D. Ezekowitz, MB ChB,Dphil, FRCP, FACCProfessor, Jefferson MedicalCollege; Director of AF Researchand Education CardiovascularResearch Foundation,Wynnewood, PA, USA

Lior Gepstein, MD, PhDProfessor of Physiology andMedicine (Cardiology) Rappaport Faculty of Medicine, Technion-Israel Institute of TechnologyHaifa, Israel

Meleze Hocini, MDHopital Cardiologique du Haut-Leveque, Bordeaux-Pessac, France

Henry H. Hsia, MDAssociate Professor of MedicineStanford UniversityStanford, CA, USA

Warren M. Jackman, MDGeorge Lynn Cross ResearchProfessor; Senior ScientificAdvisor, Heart Rhythm Institute University of Oklahoma Health Sciences CenterOklahoma City, OK, USA

Jonathan M. Kalman, MD, PhDProfessor of Medicine, University of Melbourne; Director of CardiacElectrophysiology and DeputyDirector of Cardiology Royal Melbourne HospitalMelbourne, Australia

Paul Khairy, MD, PhDCanada Research Chair,Electrophysiology and Adultcongenital Heart DiseaseDirector, Adult Congenital HeartCenter, Montreal Heart InstituteAssociate Professor of MedicineUniversity of MontrealMontreal, QC, Canada

Nassir F. Marrouche, MD, FHRSAssociate Professor of MedicineExecutive Director, CARMA CenterDirector, CardiacElectrophysiology Laboratories;Director, Atrial FibrillationProgram, University of UtahSchool of MedicineSalt Lake City, UT, USA

John M. Miller, MDProfessor of MedicineIndiana UniversityIndianapolis, IN, USA

Robert W. Rho, MDCardiac ElectrophysiologySutter Pacific Medical CenterSan Francisco, CA, USA

Paul Wang, MDProfessor of MedicineStanford UniversityStanford, CA, USA

UC FACULTYNitish Badwhar, MDAssistant Professor of MedicineDivision of Cardiology,Electrophysiology ServiceUniversity of California, San FranciscoSan Francisco, CA, USA

Noel G. Boyle, MD, PhDClinical Professor of MedicineDivision of CardiologyDavid Geffen School of Medicine at UCLALos Angeles, CA, USA

Byron K. Lee, MDAssociate Professor of MedicineDirector of the ElectrophysiologyLaboratories and ClinicsUCSF, Division of CardiologyUniversity of California, San FranciscoSan Francisco, CA, USA

Randall J. Lee, MD, PhDProfessor of Medicine, Division of Cardiology, University of California, San FranciscoSan Francisco, CA, USA

Sanjiv M. Narayan, MD, PhDAssociate Professor of Medicinein Residence; Co-Director, EPFellowship Training ProgramDirector, VA EP ProgramUCSD School of MedicineSan Diego, CA, USA

Jeffrey E. Olgin, MDChief, Division of CardiologyProfessor of MedicineUniversity of California, San FranciscoSan Francisco, CA, USA

Melvin Scheinman, MDProfessor of Medicine, EmeritusWalter H. Shorenstein EndowedChair in CardiologyUniversity of California, San FranciscoSan Francisco, CA, USA

Vasanth VedanthamAssistant Professor of MedicineUniversity of California, San Francisco San Francisco, CA, USA

FRIDAY, SEPTEMBER 7, 20127:00 am Continental Breakfast and Registration

7:55 Welcome and Introductions

SUPRAVENTRICULAR TACHYCARDIASChairs: Nitish Badhwar, MD and Susan Eisenberg, MD

8:00-8:30 Use of Novel Pacing Maneuvers for Melvin Scheinman, MDDiagnosing Supraventricular Tachycardia in the EP Lab

8:30-9:00 Mapping and Ablation of Junctional Nitish Badhwar, MDTachycardias

9:00-9:30 Ablation of Posteroseptal APs – Tips/Tricks Warren Jackman, MD

9:30-10:00 Use of the ECG for Localizing Atrial Jonathan Kalman, MD, PhDTachycardias

10:00-10:15 Break

ATRIAL FIBRILLATIONChairs: Gregory Marcus, MD, MAS and Sanjiv Naranyan, MD

10:15-10:45 Upstream Therapy for AF (ACE, ARB, Statin) – Jeffrey Olgin, MDIs There a Role?

10:45-11:15 Genetics of Human AF Gregory Marcus, MD, MAS

11:15-11:45 New Oral Anticoagulant Choices for AF – Michael Ezekowitz, MD,Which One for Which Patient? ChB, Dphil

11:45-12:15 pm Panel Discussion: Use of Newer Anticoagulants Surrounding Ablation Procedures – Current PracticePanel: Michael Ezekowitz, MD / Jonathan Kalman, MD, PhD /Nassir Marrouche, MD / Meleze Hocini, MD

12:15-1:15 Lunch (provided)

1:15-1:45 Role of Cardiac MRI for Guiding AF Ablation: Nassir Marrouche, MDExpensive Niche or Critical Element ofRisk Stratification and Follow-up?

1:45-2:15 Should Balloon Ablation Be Used For All Edward Gerstenfeld, MDParoxysmal AF Patients?

2:15-2:45 Update on Clinic Outcome After Focal Sanjiv Naranyan, MDImpulse and Rotor Modulation For the Treatment of Persistent AF

2:45-3:00 Break

3:00-3:30 Debate: Linear Ablation Should be a Moderator: Robert Rho, MDStandard Part of AF Ablation in Pro: Meleze Hocini, MDPersistent AF Con: Gregory Feld, MD

3:30-4:00 “Asymptomatic” Cerebral Thromboemboli Jonathan Kalman, MD, PhDAfter AF Ablation

4:00-4:30 Left Atrial Appendage Closure for Stroke Randall Lee, MD, PhDProphylaxis in AF

4:30-5:00 Hybrid Ablation of AF in the Operating Paul Wang, MDRoom: Is There a Need?

5:00-5:30 Panel Discussion/Wrap-UpChair: Gregory Marcus, MDPanel: Meleze Hocini, MD / Gregory Feld, MD / Jonathan Kalman, MD /

Sanjiv Naranyan, MD / Randall Lee, MD, PhD

5:30-6:30 pm Wine & Cheese Reception and Poster Session

THE CALIFORNIA HEART RHYTH September 7-8, 2012

HM SYMPOSIUMJW Marriott Hotel San Francisco, CA

SATURDAY, SEPTEMBER 8, 20127:00-8:00 am Continental Breakfast

SUDDEN DEATH AND ARRHYTHMIA SYNDROMESChairs: Zian Tseng, MD, MAS and Vasanth Vedantham, MD

8:00-8:30 Pluripotent Stem Cells: Implications for Lior Gepstein, MD, PhDBasic and Translational Cardiac Electrophysiology

8:30-9:00 Redefining Sudden Cardiac Death: Insights Zian Tseng, MD, MASfrom the Comprehensive UCSF SCD Study

9:00-9:30 ECG Screening and Risk Stratification in Byron Lee, MDCompetitive Athletes

9:30-9:45 Break

9:45-10:15 Risk Stratification of Sudden Death in Paul Khairy, MD, PhDACHD: Do Current Adult Guidelines Apply?

10:15-10:45 Early Repolarization / J Wave Syndrome: Charles Antzelovitch, PhDMechanism

10:45:11:15 Early Repolarization / J Wave Syndrome: Meleze Hocini, MDRecognition and Management

11:15-12:15 pm Challenging Inherited Arrhythmia Case StudiesChair: Melvin Scheinman, MDPanel: Jonathan Kalman, MD / Charles Antzelovitch, PhD /

Paul Khairy, MD, PhD / Meleze Hocini, MD / Zian Tseng, MD, MAS

12:15-1:15 Lunch (provided)

VENTRICULAR TACHYCARDIAChairs: Edward Gerstenfeld, MD and Noel Boyle, MD

1:15-1:45 What Can We Learn From Animal Models J. Kevin Donohue, MDof Ventricular Tachycardia?

1:45-2:15 Mapping and Ablation of Challenging Samuel Asirvatham, MDOutflow Tract VTs: Pulmonary Artery, LVOT, Epicardial

2:15-2:45 Mapping of VT in Coronary Artery Disease: John Miller, MDDoes Entrainment Still Have a Role in the Era of Substrate Modification?

2:45-3:15 New Approaches to Mapping and Ablation Edward Gerstenfeld, MDof VT in Ischemic Cardiomyopathy

3:15-3:30 Break

3:30-4:00 Utility of Cardiac MRI for Identifying the Timm-Michael Dickfeld, MD, PhDArrhythmia Substrate During VT Ablation

4:00-4:30 Management of Ventricular Arrhythmias Kalyanam Shivkumar, MD, PhDin NICM: Catheter Ablation and Beyond

4:30-5:00 Mapping and Ablation of Septal VT in Andre d’Avila, MD, PhDNonischemic Cardiomyopathy: Role of Bipolar RF, Needle Intramural Ablation, Intracoronary Ethanol Ablation

5:00-5:30 Mapping and Ablation of VT in the Sanjay Dixit, MDOperating Room

5:30-6:00 Panel DiscussionChair: Edward Gerstenfeld, MDPanel: Kalyanam Shivkumar, MD, PhD / John Miller, MD /

Andre d’Avila, MD, PhD / Sanjay Dixit, MD / Henry Hsia, MD

6:00 pm Adjourn

HOW TO ENROLLAdvanced registration closes one (1) business dayprior to start of course.

Tuition: $425 Physicians

$325 Nurses/Allied Health Professionals

$75 Fellows*

* Complimentary with abstract acceptance and poster presentation

Payment can be made by Visa, MasterCard, AmEx or check.

REGISTER VIA:Online: www.cme.ucsf.eduMail: Complete course registration form

and send with payment to:UCSF Office of CMEP.O. Box 45368San Francisco, CA94145-0368

Fax: Fax completed registration form to:(415) 502-1795 (be sure to includeyour credit card number)

Phone: To register by phone or to inquire aboutregistration status, please call UCSF’s CMERegistration Office at (415) 476-5808.

Please check our website for up-to-date informationon the course: www.cme.ucsf.eduREFUND POLICY Cancellations received in writing before the first day of the course will be refunded, less a $75administrative fee. No refunds will be made oncancellations received after that date.

CONFERENCE LOCATIONEnjoy San Francisco’s renowned attractions such asthe historic cable cars, shopping in Union Square, or visit San Francisco’s culinary hub at the FerryBuilding.

JW Marriott Hotel San Francisco is just steps fromUnion Square and the Theatre District.

A block of guestrooms has been reserved at thespecial UCSF conference rate of $248/night. You areurged to make your reservations early. The cut offdate is August 15, 2012, or until the group roomblock is filled. After this date, rooms will be providedon a space-available basis only. To make hotelreservations on-line, go to www.marriott.com, usebooking code: hrshrsa.

If you prefer to telephone in your reservation, call800-228-9290 and identify yourself as a member ofthis UCSF conference to receive the special rate.

By staying at the host hotel, you help UCSF meet itscontractual obligations and keep registration feesreasonable.

RENTAL CAR Hertz is offering special rates for participants of this conference; simply call 800-654-2240 and refer to convention number # 03BW0131, or call your travel agent. You may also make reservations atwww.Hertz.com. Advance reservations arerecommended.

AIR TRANSPORTATIONUCSF has negotiated special fares with Americanand United Airlines for our course attendees. You mayuse the following tour codes to book on your own:American (800) 433-1790 code: 1392BLUnited (800) 521-4041 code: 510CF

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REGISTRATION FEES (Receipt/Confirmation will be mailed within two to four weeks):£ $425 Physicians £ $325 Nurses/Pharmacist/Allied Health Professionals £ $75 Fellows (Complimentary with abstract acceptance and poster presentation.)

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Refund Policy: Cancellations received in writing before the first day of the course will be refunded, less a $75 administrative fee. No refunds will be made on cancellations received after that date.

Please check our website for up-to-date information on the course: www.cme.ucsf.edu.

CALIFORNIA HEART RHYTHM SYMPOSIUMSeptember 7-8, 2012JW Marriott HotelSan Francisco, California

MDM13A03

Cable Car Line

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YERBA BUENAGARDENS

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STS PETERAND PAUL

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RINCONCENTER

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GOLDENGATE UNIV.

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CALTRAINDEPOT

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JW MarriottHotel

JW Marriott Hotel San Francisco500 Post Street San Francisco, CA 94102(415) 771-8600www.marriott.com

Mail to : UCSF Office of CMEP.O. Box 45368San Francisco, CA 94145-0368Fax: (415) 502-1795

Online registration: www.cme.ucsf.eduRegistration Information: (415) 476-5808Course Information: (415) 476-4251

Course Registration Form

www.cme.ucsf.edu

For more information

or to register online

visit our website at

www.cme.ucsf.edu.

You may also reach

us by calling the

Office of CME at

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emailing:

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0569

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UCSF Box 0742

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State of the Art Advanced Heart

Failure and Arrhythmia Management

October 27, 2012

Stanford Court Hotel

San Francisco, California

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