_ _

Frontiers in the Chemical Sciences

ISelected and with an introduction by

William Spindel and Robert M. Simon, National Research Council

This collection of 38 articles from the pages ofScience shows chemists unraveling the mysteriesof molecular reactivity, developing powerfulanalytical and theoretical tools, exploring andexploiting new pathways for catalysis andsynthesis, and contributing to disciplines asdiverse as biology and materials science.Focusing on such themes as fundamentalchemical change and extreme molecularcomplexity, this volume takes the reader on atour of the contemporary research frontiers inchemistry. Articles by some of the leadingscientists in their respective fields cover new

work in seven key areas: understandingchemical reactivity, chemical analysis, theoreticalchemistry, chemical catalysis, organic synthesis,the chemistry of life processes, and thechemistry of new materials. Two Nobel lecturesare included.

592 pp.; fully indexed and illustratedHardcover $29.95 (S23.95 for AAAS members)Softcover $17.95 ($14.35 for AAAS members)

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I068 SCIENCEI VOL. 242

POSITIONS WANTED

Japanes Life Sciences Translations: articles, patents,opposition statements, other documents translated fromJapanese in cell biology, microbiology, mycology, plantpathology, immunology, pharmacology, and relatedfields. 1025 Laurel Street #3, Menlo Park, CA 94025.Telephone: 415-321-6317.

Immunologist, Gencticist, Ph.D. (1984). Academicresearch training in transplantation immunogenetics.Postdoctoral experience in molecular genetics. Broadrange of skills induding flow cytometry, cell culture,immunoassay (EIA, RIA, immunohistocheyistry), anti-body production/purification. Moleculr biology experi-ence includes Southern, Northern, and Western blotting,

in situ hybridization, and PCR. Seeking challenging

resarch position in industrial, clinical, or academic set-

ting. Box 169, SCIENCE.

I8 NOVEMBER I988

POSITIONS WANTED

Flow Cytomet Operator experienced in immunofluo-rescence and cell cyce analysis, lymphokine activation,membrane potential and sorting. Available immediately.Will relocatc. 2558 South King Road #253, San Jose,CA 95122.

POSITIONS OPEN

ANATOMISTThe Department ofAnatomy, University ofSaskatche-

wan, College of Medicine, mvites applications for afaculty position at the assistant professor level. Appli-cants should have postdoctoral experience with a strongresearch program in fucionlcoprative/evolutionary

morphology, craniofacial biology, or human kinetics.

The successful candidate will be responsible for teachinggross and neuroanatomy to physical therapy students. Inaccordance with Canadian immigration requirements, prioritywill be given to Canadian citizens and permanent residents.

Applications, induding curriculum vitae, names ofthree referees, and an outline of proposed research andprevious teaching experience should be submitted by 15January 1989, to:

Dr. G. D. BurkholderDegrtment ofAnatomy

Cliege ofMedicineUniversity of SaskatchewanSaskatoon, Saskatchewan

Canada, S7N OWO

ANATOMIST. Tenure-track faculty position offersan excellent opportunity for a balanced emphasis on bothteaching of human gross anatomy and research in thearea of neuroanatomy and/or neuroendocrinology. Thecandidate must have a Ph.D. in anatomy or related

subject, postdoctoral training, and record ofindependentraesarch. Applicants should submit resume, transcripts,research plans, and arrange to have three letters ofrecommendation sent to: Rajen Anand, Chair, Depart-ment of Anatomy and Physiolog Califo taUniversity, Lon Beach,CA 90840-3701. Positionopen until * interviews to commence February1989. CSULB is an Equal Opportunity/Afirmative ActionEmployer.

AQUATIC ECOLOGISTARIZONA STATE UNIVERSITY

The Department of Zoology at Arizona State Univer-sity invites applications for a tenure-track faculty positionin aquatic ecology at the assistant professor leve. Thesuccessful candidate will be expected to excel in researchand teaching. Projected starting date is 15 August 1989and applications should be received by 1 January 1989.Send curriculum vitac, statement of research and teach-ing interests, sclected reprints, and at least three letters ofrecommcndation to: Dr. Michael C. Moore, Chair,Aquatic Ecology Search Committee, Department of

Zoology, Arizona State University, Tempe, AZ85287-1501. Applications from two individuals for asingle shared appointment will be considered. ArizonaState University is an Equal Employment Opportunity/Afir-mative Action/Title IX Employer. Women and minorities arestrongly encouraged to apply.

ASSISTANT PROFESSORBEHAVIORAL NEUROSCIENCE

The Department of Behavioral Neuroscience at theUniversity of Pittsburgh seeks applicants for a tenure-track position which could begin in the fall 1989.Applicants should be interested in the involvement ofsecond messenger systems in neural function and/or inmolecular neurobiology. Applicants will be selected forinterviews on the basis of their record of research accom-plishment, their potential for developing a strong and

mteractive research program, and their ability to partici-pate in undergraduate and graduatc cducation. Curricu-lum vitae, selected reprints, a brief statement of futureresearch interests, and three lctters ofrefercncc should besent to: Faculty Search Committee, Department ofBehavioral Nauroscicnce, University of Pittsburgh,Pittsburgh, PA 15260. Applications will be reviewedbeginnliing 15 January 1989.

The University of Pittsburgh is an Equal Opportunity/Affirmative Action Employer.

RESEARCH INSTITUTE OFSCRIPPS CLINIC

AUTOIMMUNE DISEASE CENTERPosition of ASSISTANT MEMBER (assistant pro-

fessor) or higher, depending on qualifications, availableto molecular or cell biologist interested in mechanisms ofautoimmunity and in using defined autoantibodies toelucidate basic questions in cell biology. Send curriculumvitae and bibliography to: E. M. Tan, AutoimmuneDisease Center, Scripps Clinic and Research Founda-tion, 10666 North Torrey Pines Road, La Jolla, CA92037.

ASSISTANT PROFESSIONAL SCIENTISTPLANT PATHOLOGIST/ECOLOGIST

The Section of Botany and Plant Pathology, IllinoisNatural History Surve located on the University ofIllinois campus at Urbana-Champaign, invites appli-cations for a full-time professional research positionfocusing on plant pathogens/diseases in shapmg thegcnetic structure of, and ecological interactions within,native plant populations. A Ph.D. degree with a researchspecialization in plant pathology or ecology, is required;postdoctoral experience is preferred. The successful can-didate will be expected to develop a vigorous, innovative,and independent rescarch program that examines theroles of plant pathogens in natural populations andcommunities and in the context of diversity theory,maintenance of polymorphisms, resistance mechanisms,occurrence ofco-evolutionary interactions, eradication ofexotic species by biological means, or environmentalstress. Opportunities to teach and advise graduate stu-dents are available by affiliation with an academic depart-ment at the Univcrsity ofIllinois. Salary will be commen-surate with qualifications and experience; starting date is1 June 1989.

Applicants should submit a resume, copies of repre-sentative reprints, a brief statement of future researchgoals, and have three letters of reference sent, all to bereceived by 9 December 1988, to: Dr. Anton G. En-dress, Illinois Natural History Survey, 172 NaturalResources Building, MC-652, 607 East PeabodyDrive, Champaign,l[L 61820-6970; telephone: 217-244-2163.

The Illinois Natural History Survey is an AffirmativeAction/Equal Opportunity Employer.

Women and minority candidates are encouraged to apply.

New York University Medical Center Department ofBiochemistry seeks to fill a tenure-track position in theareas of molecular biology, developmental biology, ormolecular genetics at the evel of ASSISTANT RO-FESSOR. Abilities of the applicant are more importantthan his or her area of research. Candidate should hold aPh.D. or M.D. degree, should have at least 2 years ofpostdoctoral research experience, and should be ready toestablish an independent research program. Applicantshould submit curriculum vitae, bibliography, letters ofreference from three persons familiar with their researchand teaching abilities, and a summary of present andfuture research intcrests to: Faculty Search Committee,Department of Biochemisty, New York UniversitvMedical Center, 550 First Avenue, New York, NY10016. An Equal Opportunity Employer M/F.

ASSISTANT PROFESSOR OFBIOCHEMISTRY

BRANDEIS UNIVERSITY

A tenure-track position at the level of assistant profes-sor is available in the Graduate Department of Biochem-istry. We arc seeking someone who plans to investigatebasic mechanisms in molecular biology, in fields rangingfrom replication to gene expression. Curriculum vitae,statement ofresearch interests, and at least three letters ofrecommendation should be sent to:

Dr. Irwin B. LevitanChairman, Search Committee

Graduate Department of BiochemistryBrandeis UniversityWaltham, MA 02254

Brandeis University is an Equal Opportunity/AfirmativeAction Employer. We are seeking highly qualified candidatesfrom all segments ofthe scientific community.

PERSONNEL PLACEMENT 1069

PersonnelPlacement

SCIENCE publishes each Friday, except the last Fridayof the year. Advertising is accepted only in writing; noabbreviations. Any deadline in ad must be at least 2weeks after date of issue in which ad appears. Also,personnel advertising is accepted only with the under-standing that the advertiser does not discriminateamong applicants on the basis of race, sex, religion,age, color, national origin, handicap, or sexual prefer-ence, SCIENCE reserves the right, in its discretion, todecline to publish advertisements submitted to it.

UNE CLASSIFIED ADVERTIING DEADUNES:Thursday, 10 a.m., 2 weeks prior to issue date (mailedon issue date). For deadlines for display advertising,please contact Scherago Associates.

POSITIONS WANTED: 40¢ per word, plus $4 for use ofbox number, per week. $10 minimum, per week.Prepayment required. This rate is available only toindividuals seeking jobs.

UNE CLASSIFIED (POSITMONS OPEN, COURSES,FELLOWSHIPS, MARKETPLACE, and so forth):$38.00 per line; $380 minimum, per week (minimumcharge covers one inch on a single column; one inchequals 10 lines of 52 characters and spaces per line).No charge for use of box number. No agency commis-sion for ads less than 4 inches. No cash discount.Prepayment required for all foreign ads. Purchaseorders and/or cover letter including billing addressrequired for all other advertising.

To ESTIMATE ad cost:Structure ad copy on a separate page, on lines of 52characters and spaces. Include any desired heading.Each line of heading, and/or extra Ine spaces, and allpartial lines (including centered reply information) arecounted as full lines. Ad titles iocated within the textare printed in boldface caps and are only 32 charac-ters per line. In ESTIMATING the cost, multiply totallines x $38.00 = approximate cost of ad. (This is anapproximate cost ONLY: Allow for variation betweenestimated lines and actual typeset lines and the result-ing final cost. Purchase orders must allow for somedegree of flexibility and/or adjustment.)

CANCELLATION POUCY:NOTE: Ad cancellations made after Thursday, TWOweeks prior to issue date incur a 10% productioncharge. Final deadline for cancellations is 12 p.m.Tuesday, ONE week prior to issue date. Cancellationsmust be in writing.

Send copy for all Positions Wanted ads and UneClassIed ads less than 1/6 page in size (39 lines) to:

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SCIENCE1333 H Stret, NW

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POSITIONS OPEN

POSITIONS- OPEN

ASSISTANT PROFESSORDEPARTMENT OF ELECTRONICS

AND INSTRUMENTATIONUNIVERSITY OF ARKANSASAT L1MTIE ROCK (UALR)

Applications are invited for the position of assistantpofessor (tenure-track) in the Department of Elec-tronics and Instrumention, College of Science andEngineering Technology at UALL The applicantshould have a Ph.D. in b g, or an appropriateparent discipline, prefrably with 1 or more years ofcxpericnce in teachng and rch. The successfil candi-datc will be required to teach graduate courses andpcrform resarchand scholarly work in the area ofbioinsumentation, beginning.spnng semester, 1989.The salary would bc compettive. Te deparment collab-orates in joint research with the Mcdical Scicnces cam-pus, VA Medical Center and thc National Center forToxicological Research. Send currikulum vitac, and twoletters of reference to: Dr. M. K am Head,Depament ofElec nicsaEd SCollege of Science and ApneinT ,Building, Room 575, 01,Sou Unir ,LitteRocpn,AR 7mt204, bA 15 Employer.Opportunity/Af/imsive Action Employer.

ASSISTANT PROFESSORDEPARTMENT OF MICROBIOLAOGYT1E UNIVERSITY OF TENNESSE

KNOXVILE,TENNESSEE,Qualifications: Doctoral degree and at least 2 Years of.

postdoctoral experience in microbiology or closely alliedbiological science; demonstrated research productivity inmolcur biology and potential excellnce in teaching

Responsibilities: Graduate -and undergraduate teach-ing in microbiology/molecular biology, cstablishment ofa productive independent rescarch program, and aca-demic responsibilities normay associated with a tenure-track faculty position.

Starting date: 1 August 1989.Applicants should submit a letter of interest accompa-

nica Dy curriculum vitae, a description of the applicant'sescarch program and career objectives, and the names,addresse, and telephone numbers of three individualswho can evaluate the applicant's qualifications for theposition. Applicants fom women and minorities are especiallyuwited. All material should be sent to: Dr. StuartRisy,Ch m , &wSearch Dep rttoflcroholog, University ofTenn Knoxville,TN 37996-0545. Nominations should be made as soonas possible; evaluation of applications will begin inJanuary 1989. The University of Tennessee is an EqualEmployment Opportnity/Affinative Action/Title IX/Section504 employer.

ASSISTANT PROFESSOR-BIOLOGYThe joint Biology Department of the College of St.

Benedict and St. John's University secks to fill a tenure-track position begining fal term 1989. The successfulcandidate will be responsible for a section of the intro-ductory course for biology majors and microbiology fornursing students. A Ph.D. is required. A strong commit-ment to undergraduate liberal arts education and exper-tise in virology or microbial ecology is preferred. Srendcurriculum vitae, dtree ktters of recommendation, andtasrpts to: KCathy -8n -ar n eei Coordi-, OigfSt. MNdct§ J56374.

Applications received af 28 December 1988 cannot beguaranteed consideration. Women and minorty applicantsare encouraged to apply.

ASSISTANT PROFESSOR OF BIOLOGY. Thecandidate will give somc lectures in the courses in cellmetabolism, cell biology, genetics and nutrition, anddirect a seminar and teach a course in his/her specialty. Aprimary rcsponsibility will be to design and direct labora-tones in cell biology and metabolism. Ideal for theperson who likes to mteract with good students in smallgroup settngs and pou-pate in a strong undergraduateresearch progam. Te posiaon is available January 1989and may continue through 1989 to 1990. Submit curric-ulum vitae along with names and tdephone numbers ofat least the reencesto: Dr. E. Perry, BiolovDepa.rtment,Knox College, Galesbug, iL 61401f.Telephone: 309-343-O112 Afirmatve Action/Equal Op-portunity Employer.

1070

POSITIONS OPEN

ASSISTANT PROFESSOR-BIOLOGYhe joint Biology Department of St. John's University

and the College ofSt. Benedict seeks to fill a tenure-tracKposition beginning fall term 1989. The successful candi-date will be responsible for a year-long human anatomy/physiology course for nursing students, and generalphysiology (fall term) and comparative physiology(spring term), both upper division courses. A strongcommitment to undergraduate liberal arts education andthe ability to direct upper division students in indepen-dent research is highly desirable. A Ph.D. is requiredandexpertse in comparative or ecological physiology isprefered. Send curriculum vitae, three letters of recom-mendation, and transcripts to: Personnel Director, StJohn's University, Colegeviile, MN 56321. Applica-tions received after 16 December 1988 cannot be guar-anteed consideration. Women and minorities are encouragedto apply.

ASSISTANT PROFESSOR-PALEOBIOLOGY.Deparnment of 17 with Ph.D. program seeks colleaguewith cxpertise in paleobiology, wit particular interestsin functional approaches and evolutionary questions, toteach undergraduatc and graduate courses and to developa strong research program. Send curriculum vitae, astatement of research and teaching interests, and threcletters of onby 1 January 1989 (Septem-ber 1989 appointment; tenure-track) to: R. V. Dimock,Chair, Depatmen of Biology, Wake Forest Univer-sity, Winston-Salem, NC 27109. Equal Opportunity!Afirmative Action.

ASSISTANT PROFESSOR OF BIOCHBMIS-TRY. Two tenure-track positions are available in theDepartment of Biochemistry, North Dakota State Uni-venity. Ph.D. in biochemistry/chemistry and postdoctor-al experence required. Ability to communicate clearly isessentl. Candidates with research interests in physicalbiochemistry, protein/membrane structure, enzymokgy,or cell/developmental biology are enco to app.Successfbl candidates are expcted to develop a strongindependent research program with potential for grantsuprt and participate i teaching of graduate andundergraduate students. Send curniculum vitae, tran-scripts, a brief description ofcurrent and future researchinterests, and three letters ofreference to: Dr. Arland E.Oleson, Serch Committee, Department ofBiochem-isy, Nlorth Daoa Stalte Univrity, Fargo, ND581E05. Available 1 July 1989; dosing date, 1 February1989. An Equal Opportunity/Affirmative Action Employer.

THE MEDICAL COLLEGE OF GEORGIAASSISTANT PROFESSOR

OFPHARMACOLOGY AND TOXICOLOGYA tenure-track facty position is available in the Depart-

ment of Pharmcology and Tbicology at the MedicalCollge of Gorgia for individuals witi a strng archbackground in areas rdated to vascular or cardiac phama-

Applicantpp hould have a Ph.D. or MD., siifcantresearh a, and the ability to

respondDto new challenges. Current senghts of ourdepartment are in the and cardio cularareas. Appoin are expected to esablish a , inde-pendent research program and participate in theeicatnof our medical and graduate studnts. Pkase send curricu-hlum vitae, bibliography, summry of prfsso aland names of dthee refeecs to: Dr. LW.

Cofo£ Geoa, Angus,ta GA 30912.¶he MedicalColicge ofGeorgia is an A rmative Action/Equal OpportunityEmp oyer.

Weste Illinois University Dcparutent of Chemistryinvites applications for tnure-tra&ASSISTANTPRO-FESSOKSHIPS in BIOCHEMISTRY and INOR-GANIC EMISTRY. Ph.D. in the field requiredwith possdoctral experience p d. De t isACS- ited with 11 fty. A st mentto tcaching and research at the undeauate and M.S.levels is expected, as is development of an extemallyfund research program. The filling ofthee positions isconingt upon fiuding. Submit rcsume and proposedresearch progam before 5 January 1989 to: SearchCommittee, 7Deprtment of hemistry, WeseM Illi-nois University, Maemb, IL 61455. Equal Opporeni-ty/Afirmative Acion Employer.

POSITIONS OPEN

ASSISTANT PROFESSOR OFPIANT MOLECULAR BIOLOGY

Applications are invited for a tenure-track facultyposition at the assistant professor level in the Departmentof Plant Science at the University of Delaware. Candi-dates should be interested in utilizing molecular tech-niques for improving diseasc resistance and other a2ro-nomic traits m maize. The faculty member would beexpected tO work cooperatively with ongoing researchprograms in maize breeding, pathology, tissue culture,and soil microbiology. Opportunities for interactionwith other molecular biologists within the College wouldbe encouraged. Teaching responsibilities indcude a grad-uate level course consistent with the individus bac-ground and depent needs. Ph.D. and postdoctoralexpenence in ant molecular biology is required. Send adescription of research interests and plans, curriculumvitae, official undergraduate and graduate transcriptsand three letters ofrecommendation by 31 January 1989to:

Dr. James A. HawkDepartment of Plant Science

Townsend HallUniversity of Delaware

Newark, DE 19717-1303

ASSISTANT PROFESSOR POSMONSDUKE UNIVERSITY MEDICAL CENTER

SECTION OF CELL GROWHI,REGULATION, AND ONCOGENESIS

DUKE COMPREHENSIVECANCER CENTER

Duke University Comprehensive Cancer Center in-vites applications for tenure-track positions in a newSection of Cell Growdt, Regulation, and Oncogenesis atthe level of assistant professor. Investigators working atthc molecular level m any area of cancer biology areencouraged to apply, but special consideration will begiven to those working in the areas of growth anddifferentiation factors, signal transduction, molecular ba-sis of oncogene action indude recessive oncogenes andmultiple drug resistance. Applicants with postdoctoralexpenence should have demonstrated high Potential for

ubstntiidemonsntrated a . Successfulcandidatesubwtantalindeappointed into a basic sciencedepartment within the Medial Center.

Applicants should send curriculum vitae, and a briefdesciption of present and proposed research to: Dr.RobertM. Bdel, Head, Section ofCell Gmwth, Regu-lation and Onc is, Duke Comprehensive CancerCenter, Box 3814, Durham, NC 27110. Applicantsshould arrange for three or more letters ofrecommenda-tons to be forwarded to the same address.To be assured of fulll consideration, application should

be received by 5 December 1988.Duke University is an Equal Opportunity/Afirmative Ac-

tion Employer.

ASSISrANT PROFESSORS-Applications are in-vited for two tenure-track positions: (i) genetics/molecu-hr genetics, botanical expertise prefcrred and (ii) verte-brate anatomy/functional morphology starting fall 1989.Commitment to liberal arts undergraduate education/rescarch. Ph.D. required. Salary competitivc with excel-lent fres. Send application, sumd, threc referenccetters, transcripts, statement of teaching philosophy/resch to: Dr. James R Hodgson, Divsion ofNatu-ral Sciences, St. Norbert Colleg, De Pere,WI 54115by 15 January 1989. Afirmative Action/Equal OpportunityEnployer.

ASSISTANT PROFESSORS-BIOCHEMISTRY-ECOLOGY-PHYSIOLOGY. Several tenure-track positions (requiring research and teaching) areanicipatcd in an cxpanding department for fall 1989.Researc areas of special interest are: biochemistry,protein-nucleic acid mteraction, protein engineering;aquatic ecology, aquatic biology; comparative or cellularphysiology. Consideration ofcandidates will begin on 12t)oember 1988. Submit inquiries, curriculum vitae,statement of interests and three letters of reference to:Dr. Wayne E. Magoe, Head, Department of Biosci-ence and B lo y, 118 Stratton Hall, DrexelUnivrsity, Phladephia, PA 19104.

Woman and minorities are strongly encouraged to apply.Drexel University is an Equal Opportunity/Affirmative ActionEmployer.

SCIENCE, VOL. 242

lo > OPTICAL MICROSCOPYAU i>: AND IMAGING IN THE

|. BIOMEDICAL SCIENCES

March 5-11, 1989

This course covers the fundamental techniques of modernoptical microscopy and the newest video and photographicimaging and enhancement methods used in biomedical re-search. Designed for research scientists, physicians, post-doctoral trainees and advanced graduate students.Through hands-on experience with state-of-the-art micro-scopes, video cameras, image processing equipment andrecorders, students will obtain, interpret, process, record andanalyze high quality microscope images. Lectures, demon-strations, and discussions complement the above. Confocallaser scanning microscopy will be covered. Applications ofoptical methods to live cells, plant and animal, will be empha-sized. Students are encouraged to bring their own researchspecimens. Enrollment limited to 20 students.Co-Directors: Colin S. Izzard, SUNY, Albany and Nina Strom-gren Allen, Wake Forest University. Faculty: K. A. Jacobson,UNC, Chapel Hill; S. J. Smith, Yale University; R. Y. Tsien,UC, Berkeley. Guest Lecturers: S. Inou6, Marine BiologicalLaboratory; E. Keller, Carl Zeiss, Inc., NY. Others to beannounced.Costs: $1,350 includes Tuition, Materials, Room/Board

Application Deadline: January 6, 1989For further information contact

Office of Sponsored ProgramsMarine Biological LaboratoryWoods Hole, MA 02543

Telephone: (508) 548-3705, Ext. 216

S_

-S~~~~~~

The Procter & Gamble Company and its Richardson-Vicks and Norwich Eaton Divisions have careeropportunities for individuals interested in regulatoryaffairs positions. Successful candidates will haveexperience in regulatory policy and drug approvalregulations. A doctoral level degree or equivalent trainingin biological sciences is preferred. These regulatoryscientists will be integralmembers ofdrug developmentteams and manage the submission and approval issueswith regulatory authorities in the United Statesand abroad.

For consideration, sendyour resume to:

Dr. Robert A. Libby, DirectorProfessional and Regulatory Affairs Division

Norwich Eaton Pharmaceuticals, Inc.P.O. Box 191 Norwich, New York 13815Procter & Gamble is an Equal Opportunity Employer, M / F

M.I.T.PRE-DOCrORAL POSMONS

MOLECULAR, CHEMICAL, & GENETIC ANALYSIS OF THE CHEMICAL-

BIOLOGIC INTERACTIONS RELATED TO CANCER & GENETIC DISEASE

WHTAKCER COLLEGE OF HEALTH SCIENCES AND TECHNOLOGYGRADUATE PROGRAM IN TOXICOLOGY

John M. Essigmann DNA adducts, structure-function relationships

James G. Fox Gastrointestinal microflora & endogenouscarcinogens

Steven R. Tannenbaum Chemistry of macromolecular adducts

William G. Thilly Mutational spectra: mechanisms & geneticepidemiology

Gerald N. Wogan DNA adducts & genetic change in carcinogenesis

Helmut Zarbl Transformation effector & suppressor genes,oncogenes

Full support (stipend and tuition) is offered to all accepted candidates.For program information, catalogue, and application,

CONTACT: Debra A. Luchanin, AdministratorStudent Office, Program in ToxicologyRoom 16-330, M.I.T.Cambridge, Massachusetts 02139(617) 253-5804

MIT is an Equal Opportunity Employer

BASIC SCIENCE RESEARCH TRAININGFOR PHYSICIAN ANESTHETISTS

Applications are invited from physicians, who havecompleted the clinical training requirements of theAmerican Board of Anesthesiology, for two to threeyear research fellowships in the laboratories of HarvardUniversity, Massachusetts Institute of Technology, orMassachusetts General Hospital.

The object is to develop broadly educated scholars whohave the inclination, training, and experience to followa career in laboratory research on problems of impor-tance to anesthesia and the basic sciences to which itrests.

Candidates must show the utmost promise for a futurecareer in fundamental research. Two appointments willbe made annually under US PHS National ResearchService Award for advanced training in physiology,biochemistry, pharmacology, biophysics, biomedicalengineering, endocrinology, or metabolism.

Interested persons should apply enclosing current cur-riculum vitae to Dr. Richard J. Kitz, Department ofAnesthesia, Massachusetts General Hospital, Bos-ton, Massachusetts 02114.

NPOSITIONS OPEN

UNIVERSITY OF CALIFORNIA-RIVERSIDE

ASSISTANT PROFESSOR-ZOOLOGYThe Department of Biology, University of California,

Riversidc, invites applications for a tenure-track positionat the assistant pro essor level. The appointmnent will beeffective 1 July 1989, with duties commencing in Sep-tember. Minimum qualifications indude postdoctoraltraining, demonstrated excellence in research, and acommitment and demonstrated ability to teach. Accept-abkc areas of research indude behavior, physiology, andpopulation biology of animals in their natural environ-ment. Teaching duties are graduate and undergraduatecourses in the individuals specialty and may indudegeneral biology, vertebrate anatomy, and/or field biolo-gy. To apply, send curriculum vitae, statement of re-scarch and teaching interests, and copies ofrepresentativepublications. Also arrange to have sent three to fiveletters of recommendation, which speak to research andteachin«, by 15 January 1989 to: Zoology SearchCommittee, Department of Biology, Umversity ofCalifrna Riverside, CA 92521. The University ofCalifomia is an Equal Opportunity/Affirmative Action Em-ployer and minority and female candidates are encouraged toapply.

ASSISTANT PROFESSORS OFBIOLOGICAL SCIENCES

Applications are invited for three tenure-track facultypositions. Successful candidates will be expected to estab-lish vigorous, independent research programs, and toreinforce our strong commitments to research, graduatetraining, and undergraduate instruction. Postdoctoralexperence is required. Competitive salaries as well asattractive facilities and start-up funds are available.Teaching responsibilities will indude introductorycourse work in biology for undergraduates and graduate-level course work in the area of expertise. To joinestablished research dusters of interactive faculy mem-bers, we are searching for the following:A BOTANIST, with research focus n ecology and/or

evolution. Teaching will indude plant anatomy.A DEVELOPMENTAL NEUROBIOTOGIST,

with research emphasis at the cellular level. Vertebratesystems preferred.A MOLECULAR CELL BIOLOGIST, using a

microbial research system (viruscs, bacteria, lower eu-karyotes).

Send curriculum vitae, statement of research interests,and names of at least three references by 15 December1988 to:

Faculty Search CommitteesT. H. Morgan School of Biological Scicnces

University of KentuckyLexington, KY 40506-0225

An Equal Opportunity/Affirmative Action Emnployer

ASSISTANT SCIENTIFIC DIRECTORImmunodiagnostics, Inc., is seeking a Ph.D. bio/

organic chemist and a Ph.D. molecular biologist, eachwith at least 2 years of postdoctoral experience. Preferindividuals with ptide synthesis/characterization orDNA sequencinglPCR/probe experience, at least tenpublications and interest/experience in development ofdiagnostic tests. Send curriculum vitae and three refer-ences to: Mark Buchanan, Ph.D., Vice Presidt,Immunodiagnostics, Inc., 562 lst Avenue South,Seattle, WA 98104. Applications deadline: 2 January1989. An Equal Opportunity/Afinnative Action Employer.

ASSISTANT/ASSOCIATE PROFESSOR. We in-vite applications for a tenure-track position availableimmediately. We seek individuals with a Ph.D. and atleast 3 years of postdoctoral training to join a groupinvestigating the structure of extracellular matrix andchondrocyte metabolism, and animal models of arthritis.For full consideration, applicants should submit curricu-lum vitae, a brief description of current research interests,and three letters of reference to: Roland W. Moskowitz,M.D., Diretor, Rheumatic Disease Unit, Depart-mcnt of Medicine, University Hospitals, Clevelnd,OH 44106. Case Westem Reserve University is an Affirma-tive Action/Equal Opportunity Employer.

ASSISTAN/ASSOCIATE PROFESSOR:MOLECULAR BIOLOGY

The Department of Pharmacology at SUNY HealthScience Center at Syracuse invites applications for atenure track position available from July 1989. Candi-dates using molecular biological techniques to studycardiovascular cell biology, neurobiology, or mcmbranetransport are especially encouraged to apply. The quali-fied individual will beepected to have or to deveiop aproductive, extramurally funded research program andtoparticipate in teaching, medical and graduate students.Send a statement of research interests, curriculum vitae,and direct three lettcrs ofreference by 1 January 1989 to:Dr. Karna Meiri, Deprtment of Pharmaclogy,SUNY Healthcnce enter at Syracuse, 766 IrvingAvenue, Syracuse, NY 13210.

An Equal Opportunity/Afirmnative Action Employer.

ASSISTANT OR ASSOCIATE PROFESSOR.We invite applications for a tenure-track position avail-able immediately. We seek an individual with an M.D. orM.D./Ph.D. with postdoctoral training in rheumatologyand either immunology and/or molecular biology with ademonstrated rcsearch program in normal animal orhuman immunobiology and/or autoimmune diseases.For full consideration, applicants should submit curricu-lum vitae, a briefdescription ofcurrent research interests,and three letters ofreference to: RolandW. Moskowitz,MD., Director, Rheumatic Disease Unit, Depart-ment of Medicine, University Hospitals, Clevend,OH 44106. Case Western Reserve University is an Afirma-tive Action/Equal Opportunity Employer.

ASSOCIATE DEAN FOR ACADEMIC AF-FAIRS-The University of Medicine and Dentistry ofNew Jersey is seeking a dynamic individual to serve as thekey person in the administration for the provision ofleadership in development, implementation, and moni-tonng ofeducationa programs. Applicants should have arelevant doctoral degree, a substantial track record on amedical school facuity, and experience in educationaladministration. The school has campuses in Piscataway,New Brunswick, and Camden, New Jersey, with a totalenrollment of approximately 520 medical students. Sendcurriculum vitae to: Office of the Dean, UMDNJ-Robert Wood Johnson Medical School, (SM) 675Hoes Lane, Piscataway, NJ 08854-5635. TheUMDNJ is an Affirmative Action/Equal Opportunity Em-ployer M/F/H/V.

ATMOSPHBERIC SCIENTIST (RESELARCH AS-SOCIATE): The Rcsearch Foundation of the StateUniversity of Ncw York seeks applicants with doctoratein atmospheric science for a position involvin researchin various areas of physical meteorology indum g atmo-spheric electricity, cloud physics and instrumentation,and adapting meteorological instrumcnts for projects.Will use anemometer, microconductivity cell, microcom-putcrs. Requiremcnts: graduate concentration in physi-cal meteorology with courses in atmospheric electricityand cloud physics, a graduate coursc in advanced elec-tronics, and 2 years ofexperience in the design, develop-ment, construction, and testing of electronic and me-chanical meteorological instruments. Salary: $25,000 peryear, fuill-time. Send rcsume, three references to: Dr.Bernard Vonnegut, SUNYA Atmospheric Science,1400 Washintn Avenue, Albany, NY 12222. Affir-mative Action/Equal Employment Opportunity Employer.

California-BIOCHEMISTRY FACULTY POSI-TION, California State University, Sacramento (CSUS).Applications are invited for a tenure-track position re-quiring a Ph.D. in biochemistry by 1 September 1989and an undergraduate degree in chemistry. Positioninvolves teachmg both lower division chemistry andgeneral biochemistry, and developing a vigorous researchprogram in biochemistry that involves both undergradu-ate and master's students. Preference given to candidateswith recent research and teaching expenence. Applica-tions incuding curriculum vitae, threeletters ofreferenceattesting to teaching and research abilities, publications,and statement offuture research work should be sent to:Professor James C. Hill, Chair, Department ofChemistry, CSUS, 6000 J Stet, Sacramento, CA95819, by 15 January 1989. CSUS is an AffirmativeAction/Equal Opportunity Employer.

TRUDEAU INSTITUTE, INC.BASIC RESEARCH SCIENTISTS

The Trudeau Institute is always interested in receivingapplications for tenure-track, full-time research staffposi-tions, from appropriately trained individuals. Appoint-ments may be made at the assistant, associate, or fillmember (professor) levels, depending on scientific abilityand past performance. Successful applicants will be ex-pected to develop independent research programs inilmunology, immunopathology, molecular immunolo-gy or related fields.The Trudeau Institutc is a free-standing, not-for-

profit, basic research institute with modern facilities, up-to-date equipment, in-house animal production, efficientmanagement and an international reputation for excel-lence. Current staff interests indude: cancer immunolo-gy, transplantation immunology, immunity to infectiousand parasitic discases, reualation of immune responses,and the production and fntion of cytokines. Adequatestart-up funding for new projects is available from Insti-tute resources. Salaries and benefits are competitive, andworking conditions are conducive to a productive careerin research.

Applications consisting ofcurriculum vitae, the namesand addresses of three references, and a brief descriptionof research interests, should be addressed to:

Dr. Robert J. North, DirectorTrudeau Institute, Inc.

P.O. Box 59Saranac Lake, NY 12983

BEHAVIORAL NEUROSCIENTISTThe Department of Psychology of the University of

Minnesota seeks applications for an assistant professor,tenure-track position from individuals specializing in thestudy of the neural mechanisms of memory, learning,motivation or perception. Applicants should have thePh.D. Postdoctoral work desirable. The individual willbe expected to initiate an active research program usingneuroanatomical, electrophysiological, neuropharmaco-logical or other modern approaches, preferably at thecelular levd. Applicants should also have broad interestsin brain/behavior relations compatible with teaching anundergraduate course in physiological psychology andparticpatin in graduate mstruction in psychology andthe university-wide Graduate Neuroscience Program.Salary is competitive and will depend on the candidate'squalifications and experience. This is a faculty position100% time appointment during the academic year, withthe initial appointment to begin 16 September 1989. TheUniversity ofMinnesota is an Equal Opportunity Employer andEducator and specifically invites and encourages applicationsJfomwomen and minorities. Candidates should submit curricu-lum vitae, at least three letters of reference, recentpublications, and a concise statement of long-term re-search interests to: Professor Dwight A. Burkhardt,Chair, Neuroscience Search Committee, PsychologyDepartment, University of Minnesota, 75 East RiverRoad, Minneapolis, MN 55455.

Application deadline: 1 December 1988.

BIOCHEMIST-MOLECULAR ENDOCRI-NOLOGIST: Research assistant professor, research as-sociate, postdoctoral research positions available forstudies related to biochemistry of reproduction. Empha-sis is on mechanism ofhormone action, receptor purfica-tion and chemistry, hormone binding inhibitors, synthe-sis and characterization ofhormone analogs. Postdoctor-al training grant positions also available. 7Please forwardcurriculum vitae, summary of research skills and experi-ence, and names ofthree references to: Leo E. Reichert,Jr., Ph.D., Department ofBiochemistry A-10, AlbanyMedical College, Albany, NY 12208.

Albany Medical College is an Equal Opportunity Employer.

BIOCHEMISTSGS12 and GS13 positions open U.S. Army Institute of

Dental Research, Washington, D.C. Individual neededto extract and isolate bioacive bone factors from bone,prepare bone implants for experimental animal use, andinvestigate and characterize biodegradable polymers. In-dividual should have some background in protein and/orpolymer chemistry and biomedical engineering, and agood background in analyical chemistry. Both positionsrequire Ph.D. in biochemistry or related science. GS13position requires 3 to 5 years ofpostdoctoral experience.Positions are available immediately. Contact: Dr. JeffreyHollingr at 202-576-3764.

SCIENCE, VOL. 2421072

POSITIONS OPEN POSITIONS OPEN

POSITIONS OPEN

BIOCHEMISTRY AND AMCROBIOLOGYTwo ASSISTANT PROFESSOR (tenure-track) po-

sitions anticipated, August 1989, in Department ofBiological Scienecs, University ofNew Orleans. Postdoc-toratc required. Biochemist expected to conduct inde-pendent research in comparative or adaptive biochemis-try; teaching indudes a basic course m biochemistry.Microbiologist expected to apply modem moleculartechniques to microbial systems; teaching indudes abasic course in microbiology. Applicants should sendr6sumi and statement of research goals and have threeletters of rcferenee sent to: Dr. G. R. Welch, Dcpart-mcnt of Biologicl Scicnces, University of New Or-leans, New Orleans, LA 70148. Deadline: 10 January1989. An AJfinnative Action/Equal Opportunity Employer.

BIOCHEMISTRY, SENIOR FACULTY POSI-TION. The Chemistry Department, Wayne State Uni-versity, is seeking an outstanding individual whose re-search interests are in a contemporary biochemical area tofill a tenured full professor position. A candidate shouldhave a strong record of attracting extramural funding, anexcellent publication record and considerable stature inthe field. An attractive, competitive package includingexcellent research and office space, and research supportwill be offered the successful candidate. Women andmembers of minority groups are encouraged to apply. TheDepartment is housed in a modem research building andisvery well equipped induding core facilities for oligonu-cleotide synthesis and automated DNA sequencing, fer-mentation, high field NMR, mass spec, molecular mod-eling, and x-ray crystallography. Collaborative interac-tions with the adjacent Medfcal School faculty and theDetroit Medical Center are facile and convenient as areinteractions with the Center for Molecular Biology,Center for Chemical Toxicology and the ComprehenslveCancer Center. Send curriculum vitae and other perti-nent information to: Dr. Richard L. Lintvedt, Chair-man, Department ofChemistry, Wayne State Univer-sity, Detroit, MI 48202. Wayne State University is an

Equal Opportunity/Afirmative Action Employer.

BIOLOGY, ASSISTANT PROFESSOR/ASSO-CIATE PROFESSOR Tcnure-track, to begin August1989, in developmental genetics, neurobiology and someintroductory level biology. Research to complementteaching duties. Prefercnce given to applicants withteaching experience. Ph.D. required; salary competitive.Opportunities for collaborative research with nearbyuniversities and laboratories. Scnd request for applica-tion with detailed curriculum vitae and statement ofcareer goals to: Dr. Dorothy F. Chappcll, Chair,Department of Biology, Wheaton Coilege, Wheaton,IL 60187. Closing date for application, 1 December1988.

HEALTH PROFESSIONS COORDINATOR/COMPARATIVE ANATOMIST. Non-tenure track,to begin August 1989, will coordinate health and alliedhealth professions advising, communication, and otheraffairs; teaching load incduding comparative anatomy.Preference will be given to comparative anatomist with

neuroanatomy training and histology. Send request forapplication with detailed curriculum vitae and statementof career goals to: Dr. David Brmce, Department ofBiology, Wheaton College, Wheaton, IL 60187. Clos-ing date for applications, l December 1988. Wheaton isa college in the broad evangelical tradition, located in thewestern suburbs of Chicago, with a biology departmentof seven members. It complies with federal guidelines fornondiscrimination.

BIOLOGY (BACTERIOLOGY/MICROBIOLO-GY): Midwestern State University, Wichita Falls, Texas.ASSISTANT PROFESSOR, tenure-track position,Ph.D. required, beginning fall 1989. Teacling responsi-bilities will indude: introductory courses in biology,microbiology, and immunology, and undergraduate andgraduate courses in bacteriology. Development of aresearch program is expected. The successful candidatewill be responsible for supervision of thesis research formaster's students. A complete resume and three or moreletters of recommendation should be received by 10Febrary 1989. Address inquiries and materials to: Dr.Norman Horner, Chairman, Search Committee, De-parment of Biology, Drawer A, Midwestem StateUniversity, WichitaF alls, TX 76308.

An Equal Opportunity/Affirmative Action Employer.

i8 NOVEMBER I988

BROOKHAVEN NATIONALLABORATORYBiology DepartmentPostdoctoral ResearchAssociate PositionsApplications are invited for postdoctoral positions in the BiologyDepartment of Brookhaven National Laboratory (BNL). Operated byAssociated Universities, Inc., under contract with the U.S. Depart-ment of Energy, BNL Is one of the nation's leading Institutionsdedicated to scientific research. It Is situated In a rural setting Inthe center of Long Island, 65 miles east of Manhattan. Research inthe Biology Department encompasses studies on molecular struc-ture, molecular genetics, DNA damage and repair, and cell biology ofplant and,animal systems. The Department contains the ScanningTransmission Electron Microscope Facility and also operates sta-tions for molecular structural studies at the National SynchrotronLight Source and the High Flux Beam Reactor.

Positions are available for collaborative studies with the principalinvestigator(s) named:* Human Cell Protein Klnase that is activated by double-strandedDNA. Involves protein purification, protein sequence analysis,monoclonal antibodies, cDNA cloning and sequencing.(C.W. Anderson)* Adenovirus Phosphoprotelns that affect virus host-range. Involvesprotein purification, protein sequencing and site-directedmutagenesis. (C.W. Anderson)* New Anti-Viral Agents. Involves characterization of an adenovirusserine endoproteinase and development of proteinase-specificinhibitors by site-directed mutagenesis. (C.W. Anderson andW.F. Mangel)* intermediate Proteln Assombies. Important In the initiation oftranscription and replication of eukaryotic promoters and origins.Measurement of molecular mass and geometry In situ usingScanning Transmission Electron Microscopy and molecular biology incollaboration with leading biochemists. (P.V.C. Hough)* Bacterlophage T7 Gone Expression, replication and packaging;interactions of T7 RNA polymerase; rapid genome sequencing.(F.W. Studier and J.J. Dunn)* Electron Energy Loss Spectroscopy of biological specimens atthe BNL Scanning Transmission Electron Microscopy Facility. Equip-ment development for new 40K STEM as well as basic research withthe present -900 STEM on elemental mapping, radiation damageand image analysis. (J.S. Wall)* Far Ultraviolet Circular Dichrolsm and FluorescenceSpectroscopy using synchrotron radiation and ultraviolet radiation-induced damage and repair of DNA. (J.C. Sutherland)

Applicants should submit a curriculum vitae, the names of threesources for reference and a letter stating the position desired withdetails of relevant experience. Appointment Is Initially for one year,renewable for up to two additional years. Salaries are competitiveand commensurate with experience.Send applications to: H.Z. Kondratuk, Biology Department,Brookhaven National Laboratory, Associated Universities, Inc.,Upton, L.i., NY 11973. Inquiries may also be sent through BITNET to:HINDlBNWX0. Equal Opportunity Empioyer m/f.

I) I I BROOKHAVEN(ii NAIONA LABORATORY

|ASSOCIATED UNIVERSITIES INC.

I

POSTDOCTORAL SCIENTISTEXPLORATORY RESEARCHAmgen is a recognized leader in the development ofhuman pharmaceuticals through applied biotechnology.Our Exploratory Research Group has an opening for aPostdoctoral Scientist to investigate proto-oncogene regu-lation of cellular proliferation. The research program willfocus on nuclear proteins that modulate cellular responsesto growth factors, lymphokines and colony stimulatingfactors.

Qualified candidates must have a recent Ph.D. in molecularbiology or a related discipline. Experience in one or more ofthe following areas is desirable: molecular cloning, geneexpression, monoclonal antibody development, tumor bio-logy, or immunocytometry.

Amgen offers a stimulating and challenging researchenvironment as well as an attractive location (about onehour northwest of Los Angeles). Amgen also provides anexcellent compensation and benefits package.

Qualified applicants should send a complete CV, includingreferences, to:

Recruitment, Dept. #354AMGEN1900 Oak Terrace LaneThousand OaksCA 91320

EquuO rtunity

ProductDevelopmentProfessional OpportunitiesPRAXIS BIOLOGICS is aggressively pursuing new challenges anddevelopments in human vaccines. This means exciting career oppor-tunities for achievement-oriented professionals.Working in this area, you will develop innovative industrial-scale pro-cesses to produce potential vaccine products and peirticipate inlaboratory, pilot and full-scale production.

Research Scientist-FermentationThis position requires a PhD in Microbiology or Biochemical Engineer-ing and at least three years post-doctoral or related experience in small-scale and pilot plant fermentation.

Research Associate-Chemical DevelopmentThis position requires a BS with at least three years of relevant work ex-perience or an MS in Chemistry or a related field. In this position, you willbe responsible for developing and performing biochemical reactions,purifications and analyses under cGMP's.

Associate Scientist-PurificationThis position requires a BS or MS in the Sciences plus four years ofrelated experience or a PhD in Biochemistry or Biochemical Engineer-ing with up to three years' post-doctoral or related experience in large-scale protein or carbohydrate purification.We offer competitive salaries and a complete benefits package. Pleasesend your resume and salary requirements to: PRAXIS BIOLOGICS,Human Resources Department, 4300 Oak Park, Sanford, NC 27330.

PRAXISBIOLOGICS

An equal opportunity employer, m/f

PROFESSOR AND HEAD OF THEDEPARTMENT OF AGRONOMYUniversity of Nebraska-Lincoln

The Department Head is responsible for the administrative leadership ofteaching, research, extension, and international programs, and for staff develop-ment in the Agronomy Department. Departmental faculty are located on the EastCampus in Lincoln and at the District Research and Extension Centers at ClayCenter, Concord, North Platte and Scottsbluff.

The Agronomy Department is a part of the Institute of Agriculture and NaturalResources and has programs in emp physiology and production, plantbreeding and genetics, soll science, range and forage management, andweed science. The Department offers the B.S., M.S. and Ph.D. degrees.Currently there are 85 undergraduate students and 145 graduate students in theprogram.

The Department consists of 49 faculty members, with 17 faculty located at theDistrict Research and Extension Centers, 96 full time staff, and 16 affiliate facultyemployed by the USDA-ARS. Most faculty have joint appointments betweenresearch and either teaching or extension.

Ph.D. in Agronomy/Soil Science or closely related field and meet the qualifica-tions for the rank of Professor in the Department. Experience in teaching,research, extension or related industry experience is required. Experience inadministration is preferred, but evidence of administrative ability is required.Demonstrated ability to communicate effectively, to work well with people withvaried backgrounds and interests, to organize and coordinate, to provide astrong liaison with the Agronomy profession, and to foster unity of faculty andstaff is necessary.

Nominations or applications will be accepted until December 10, 1988 (or untilsuitable candidates apply thereafter). Applicants are requested to remit letter ofapplication, vitae, and names of three references to:

Dr. Ilin T. Omtvedt, Vice ChancellorInstitute of Agriculture and Natural ResourcesUniversity of Nebaska-Lincoln202 Agricultural HallLincoln, Nebraska 6J583-0708Phone: (402) 472-2671

Affirmative Action/Equal Opportunity Employer

NATIONAL CANCER INSTITUTENational Intitutes of Helth, Pubic Helt Service

CANCER PREVENTIONFELLOWSHIP PROGRAM (CPFP)

The DIVISION OF CANCER PREVENTION AND CONTROL (DCPC) isaccepting applications for the Cancer Prevention Fellowship Program(CPFP). The primary purpose of this program is to attract individuals froma multiplicity of health science disciplines into the field of cancer preventionand control research. The program provides for: participation in theDCPC Cancer Control Academic Program (a formal four-month course incancer prevention and control); 20 months at NCI working directly withindividual preceptors on ongoing cancer prevention and control projects;and, one year at a DCPC-approved cancer control program or Stale HealthDepartment (may be optional). Funding permitting, up to 10 Fellows willbe accepted for up to three years of training, beginning August 27, 1989.

APPLICANTS MUST (BY THE DEADUNE):1. Possess an M.D. or D.O. degree from a U.S., territorial, or Canadian

medical school OR foreign medical graduates must have currentECFMG/FMGEMS certification and have completed one yearresidency in a training program approved by the Accreditation Councilfor Graduate Medical Education --OR-- Possess other accredited U.S.,territorial, or Canadian doctoral degree (Ph.D., Dr. RH., D.D.S., etc.) ina discipline related to cancer prevention and control research(biomedical, medical, nutritional, public health or behavioral sciences).Foreign doctoral graduates must provide documented evidence thatthe foreign education is comparable to doctoral education received inaccredited institutions noted above;

2. Possess U.S. citizenship or be a resident alien eligible for citizenshipwithin four years;

3. Complete and return the application packet by the deadline (includingarranging for official academic transcripts and four current, originalletters of reference to be sent directly by the academic institutions andreferees to the CPFP Coordinator).

For questions conceming the program's scientific or administrative aspects, pleasecontact Dr. Peter Greenwald or Mrs. Barbara Redding at (301) 496-8640. Applicationpackets may be obtained by sending a POSTCARD with your name and home addressto CPFP Coordinator, NIH/NCI/DCPC/CCAB, EXPS Terrace Level, 9000 RockvillePike, Bethesda, MD 20892. Please do not send any material until after you have readthe instructions in the application packet.DEADLINE FOR RECEIPT OF APPLICATIONS: JANUARY 11, 1989

NIH is an Equal Opportunity Employer

L=

Assistant!Associate

Investigator-The Lindsley F. Kimball

Institute of TheNew Ybrk Blood CenterPosition available for Ph.D. inmolecular biology/immunology towork with Dr. A.R. Neurath, bio-chemical virology laboratory.

Applicant must have four or moreyears of postdoctoral experience,past grant support and publicationrecord demonstrating innovativeand independent research accom-plishments. Will also be expectedto participate in the design ofimmunogens eliciting B- and T- cellimmunity against human viruses,including the human immunedeficiency virus. Salary range$32,000-$50,000, dependingupon experience and rank ofappointment.Send resume and three letters

of recommendation to:S.L./Human Resources Dept

The New Ybrk Blood Center310 East 67th Street, NY, NY 10021

THE NEW YORKBLOOD CENTER-

Equal Opportunity Employer M/F

The International Atomic Energy Agen-cy seeks for its Laboratories in Sei-bersdorf, near Vienna a Head of theAgriculture Laboratory for the applica-tion of nuclear techniques in agricul-ture. The incumbent coordinates theactivities of a staff of 70 engaged inresearch and training activities in cropnutrition, plant breeding, insect con-trol, agrochemicals and residues andanimal production and health. Emphasisis on research, training courses andfellowships in relation to agriculturalprogrammes in developing countries.Provides liaison between the Directorof IAEA's Laboratories at Seibersdorfand the Director of Joint FAO/IAEADivision in Vienna. PhD in an agricultur-al science, research and administrativeexperience required. Background in nu-clear techniques essential.

Tax free emoluments of approx. US$59.000,-p.a. Additional allowances ifmarried. Six weeks annual leave. Traveland removal expenses paid. Interestedpersons should send their curriculumvitae quoting VN No. 88/042 to theDivision of Personnel, InternationalAtomic Energy Agency, P.O. Box 100,Wagramerstrasse 5, A-1400 Vienna,Austria.

Dean, College of EngineeringUniversity of California

RiversideThe University of Califomia, Riverside, invites applications and nominations forthe Dean of Engineering in the newly created College of Engineering. TheDean will be responsible for. recruiting the initial faculty and working withthem to prepare the final undergraduate curricula in chemical engineering(with a biochemical engineering emphasis), electrical engineering, and environ-mental engineering, assisting in designing the permanent facilities; and prepar-ing for graduate instruction. Other majors will be added later.

The successful candidate should have: (1) a record of achievement appropriatefor appointment as full professor in the University of California; (2) a provenrecord of administrative accomplishment; (3) an educational perspective andphilosophy consonant with strong undergraduate education within the contextof a research and land grant university, and (4) a demonstrated capacity forinnovative leadership and for consultative and collaborate work.

UCR is an equal opportunity/affirmative action employer. Applications fromand nominations of qualified women and minority candidates are particularlyencouraged. Salary is commensurate with experence.

Consideration of candidates will begin on January 1, with a contemplated ap-pointment date of July 1, or earlier if mutually agreeable. Nominations and ap-plications, including a current professional resume containing the names andaddresses of at least 3 referees, should be sent to:

Chair of the Search Committee-\ for the Dean of Engineering

J Office of the Chancellor/ University of California

Riverside, CA 92521

i

I"

POSITIONS OPEN

LYNCHBURG COLLEGE IN VIRGINIALynchburg College seeks modem BIOLOGIST to

chair six-person department revising curriculum, improv-ing instruction, and planning facilities renovation andaddition. Seek individual who can teach microbiolog0yplus either physiology or cell biology. The position istenure-track and requires the doctorate. Review of appli-cations will begin in late November and continue unti anappointment is madc.The College is a coeducational, liberal arts institution

of over 2,40 students, affiliated with the ChristianChurch (Disciples of Christ), a liberal Protestant denom-ination. Lynchburg is a community of 150,000 personslocated near the Blue Ridge Mountains, 3½ hourssouthwest ofWashington, D.C. The city has a diversifiedeconomic basc, exceilent public schools, a mild climate,and many opportunites for recreation. Five collegescnhance its cultural life.

Lynchburg College strongly encourages applications fromwomen and from members of minrity groups. Please sendcredentials, induding curriculum vitae and names ofreifrences to: Dr. Orrie 0. Stcnroos, Chair, Depart-ment ofBiology, Lyndhburg College, LynchbWg, VA24501. Equal Opportunity Employer.

BIOLOGY-INSTRUCTORThe joint Biology Department of the College of St.

Benedict and St. John's University is seeking to filla 1-year position, possibility of renewal for up to 3 years,ginning fall tcrm 1989. A Master's ofScience degree in

biology IS rquired and some teacing cxperience at theundergraduate level is preferred. Duties will indudecoordinating and teaching introductory biology labora-tories and chn nonmajors courses in environmentaland life science. Send curricuhlum vitae, three letters ofrecommcndation, and transcripts to: Kathy Flynn,Wage and Benefit Coordinator, College of St. Bene-dict, St Joseph, MN 56374. Applications received after28 December 1988 cannot be guaranteed consideration.Women and minorities are encouraged to apply.

BOTANISTThe Department of Botany expects to have a tenure-

track position available for an assistant professor at theHamilton (first semester) and Middletown (second se-mester) regional campuses of Miami Univcrsity begin-ning 23 August 1989. Responsibilities indude teachingintroductory botany and other courses that meet theunivcrsity science requirements. A broad backgroundand Ph.D. in botany or related field are required br thisposition as is an enthusiastic dedication to teaching.Professional scrvice to the campus, community, andregion is another major component of the position.Sholarship is also required anmay b ither discipline-or pedagogy-oriented. Curriculum vitae, a one-pageewpication of teaching philosophy, a one-page summary

so igoals, and at least thrce lettcrs of recom-mendation sfioud be received by 6 January 1989. Mate-rial should be mailed to: Martha J. Powell, SearchCommittee Chair, Department of Botany, MiamiUniveity, Oxford, OH1 45056. Miami University is anAJfirmative Action/Equal Opporunity Employer.

AGNES DUGGAN BROWN CHAIR INONCOLOGIC RESEARCH

The James Graham Brown Cancer Center of theUniversity of Louisvillc is seeking a qualified individualto fill the Agnes Duggan Brown Chair in OncologicResearch. In addition to the generous support providedby the chair, there will be an unusual opportunity todevelop a research program of substntial dimensionswith currently available istitutional resources. The indi-vidual should hold an M.D. or Ph.D. and have ademonstrated, though not necessarily long rocord ofaccomplishment in cancer research. Individuals withcxpertise in the areas of oncogene and/or antioncogeneregulation, growth factors, signal transduction, or otherareas relating to molecular carcinogenesis are particularlyencouraged to apply. Interested individuals should sub-mit a bnef descnption of their research interest, curricu-lum vitae, and the names of three knowledgeable refer-ences on or before 1 January 1989 to: Warren E. Ross,MD., Director, James Graham Brown Cancer Cen-ter, University of Louisville, Louisville, KY 40292.The University of Louisville is an Affirmative Action/EqualOpportunity Employer.

I076

BIOLOGY: FULL-TIME POSMON beginningSeptember 1989. Ph.D. in biology with strong compe-tence in zoology. Rank and salary open depending onexperience. Teaching courses such as ariatomy, physiolo-gy, genetics, embryology and related general educationcourses. Send letter of application, rdsumd and tran-scripts and arrange for three letters ofreference to be sentto: Dr. Arden Slottcr, Dean of Acadic Affiirs,Bhluifon College, Bhifton, OH 45817. An AfirmativeAction/Equal Opportunity Employer.

CELIJMOLECULAR BIOLOGIST-The BiologyDepartmt is seking a cell/molecular biologist workingon ekayotic systems for a tenure-eaning position at thelevel of assistan/associate professor. The 9-month salarywill be netbl. Postdocorale is desirabk.Candidates will be expected to tec an upper l celbiology course, graduate courses in area of expertise and todevelop extramural support for an active research program.Application should include complete curriculum vitae,state nt of research interests and three letters of recom-mendation. Cosing date: 31 January 1989. Send to:Sear Commi Cell BioIy Departm ofB -

gy Uni" of South F ida Tampa, L 33620-150. USF is an Equal Opportunity/AJirmative Action

Employer and invites applications from qualied individuals.

CHAIRMAN AND PROFESSORPRITZKER DEPARTMENT OF

ENVIRONMENTAL ENGINEERINGILLINOIS INSTITUTEOF TECHNOLOGY

Illinois Institute of Technology (IIT) invites applica-tions and nomninations for the position ofChairman andProfessor in the Pritzker Department of EnvironmentalEngineering, to be filled by August 1989. The depart-ment has six regular faculty members and one researchproessor and awards MS. and Ph.D. degrees. There areapproximately 80 current full-time and part-time gradu-ate students. The deparmet conducts externaLly spon-sored research in excess of$1 million annually, much ofitthrough the Industrial Waste Elimination Research Cen-ter (lWERC)-a U.S. EPA-supported Center of Exccl-lence. A major resea thrust of the department isindustrial and hazardous waste managemcnt. This areabenefits from cxtensive collaboration with the IIT Re-search Institute, for example, through the jointly sTon-sored Center for Hazardous Waste Management. Oherareas of interest include water and wastewater engineer-ing, environmental monitoring and assessment, air re-sources engineering, environmental chemistry, and mi-crobiolgy and related policy issues. The successful can-didate will be a nationally recognized individual with astrong track record in sponsored research who canprovide leadership to an active and diverse group ofaculty and students, and who can increase interactionswith industrial sponsors and governmental organiza-tions. The succssul candidate must have an earneddoctorate in environmental cngineering or in a relatedfield, and be qualified for appomtment at the rank of fullprofessor. Please send resumc and names of three refer-cnces or ktters of nomination to: Dr. Darsh T. Wasan,Cairman of the Environmental Engneerin Chair-man Search Committee, Office of the Vi Presidentfor Research and Technology, inois Institute ofTechnology, Chicago, IL 60616. The search will re-main open until the position is filled. IIT is an EqualEmployment Opportunity/Aflirmative Action Employer.

UNIVERSITY OF GUAMis seeing qualified candidates forDEAN OP GRADUATE SCHOOL

AND RESEARCHApplicants must be either U.S. citizens or have perma-

nent resident status, have a Ph.D. from an accrediteduniversity, have suitable administrative experience, andhave academic qualifications normally expected for ap-pointment in senior professorial rank.

Position beins 1 Augut 1989 or earlier. Application,curriculum vitae, official transcripts, and three recentletters of recommendation shoud be sent before 1February 1989 to: Dr. Hans C. Blaise, Chair, SearchCommitte, c/o College of Business and Public Ad-ministation, Universi ofGuam Station, Mangilao,Guam, 96923.An Equal Opportunity/Ajfirmative Aaion Employer.

CHAIR, BIOLOGY DEPARTMENTApplications or nominations are invited for the posi-

tion ofProfessor and Chair ofthe Biology Department atGeorge Mason University. This is an excellent opportu-nity for a dynamic leader with a commitment to under-graduate and graduate education, a nationally recognizedresearch program, and proven administrative abilities.The chair must lead a department of 28 faculty with abroad range of research interests. The department offersB.S./B.A. degrees in biology and medical technology,and M.S. degrees in the following areas: environmental,organismal, interpretive, molecular/microbial/cellular,s ad/volutionary/population biology. The depart-ment also offers an innovative, broadly based Ph.D. inenvironmental biology-public policy.George Mason is a rapidly growing state university in

the metropolitan Washington, D.C., area, convenient tofunding agencies and governnent and industry searchfacilities. Candidates should send a letter of interest andcurriculum vitae, and request that three letters of refer-ence to be sent to: Dr. Jane Ilinn, Psychologv Depart-ment, George Mason University, UIVersity Drive,Fairfax, VA 22030. Applications are due by 10 January.George Mason University is an Equal Employment Opportuni-ty/AJirmnative Action Institution.

CLINICAL PHARMACOLOGISr: Tenure-trackposition. Acceptng applications at assistant/associate/filllprofessor leveL. Must have M.D. or M.D./Ph.D. degrce,significant postdoctoral research expenence and demon-strated ability to be productive in an academic setting.Salary will be commensurate with experience. Specialconsideration will be given to candidates with pertisein cancer/immune pharmacologv. Successful applicantswill be expected to have or develop strong, independetmsearch programs with extemal funding as well asparticipate in teaching at both graduate and medicalstudent levels. A wide variety ofinteractions with currentfaculty members is possible and encouraged. Closingdate is 30 Dccember 1988. Candidates should submit altter of application, a brief statemcnt of research objec-tives, curriculum vitae, and five letters of recommenda-tion to: Diane H. Russel, Ph.D., Professor andCh s, Departnt of Pharmacology andThe tics, College of Medicine, MDC-9, Univr-sity ofSouth Florida, Tampa, FL 33612. The Universi-ty ofSouth Florida is an Equal Opportunity/AJfirmative ActionEmployer.

DIRECTORIRA C. DARLING CENTERMARINE LABORATORY

CENTER FOR MARINE STUDIESUNIVERSITY OF MAIN

Scientist with administrative and research expenence issought as director of the Ira C. Darling Center, themanne laboratory of the University of Maine. ThcDarling Marine Center is used by Umversity faculty andstudents (resident and Orono-based) as well as visitingscientists working on a variety of marine problemsrelated to the environment and resources (includingaquaculture) of the GulfofMainc. The Ccnter is close tothe Bigelow Laboratory for Ocean Sciences and theBureau ofMarine Sciences ofthe Marine Department ofMarine Resources with which it and the University havegrowing ties.

Responsibilities will indude management of the Cen-ter and supervision of its staff, the development of itsreearch, educational, and public service activities; ex-pending its support and use by visiting investigators; andthe development of public and private sources of sup-port.

This position reports to the Director of the Universi-ty's Center for Marine Studies.

Opportunities exist for an academic appointment withan appropriate department. Field of expertise is open.Salary is competitive. The University ofMaine is an EqualOpportunity Employer. Applications from women and minor-ities are strongly encouraged.Send curriculum vitae and names ofthree references by

15 December 1988 to: Chair, Search Committee,Center for Marine Studies, 14 Coburn Hall, Univer-sity of Maine, Orono, ME 04469-0114.

The University ofMaine is an Equal EmploymentOpportunity/Alfirmative Action Employer.

SCIENCE., VOL. 242

POSITIONS OPEN POSITIONS OPEN

WhenApril 3-June 10, 1989

WhereCatalina Island Marine Science CenterTwo Harbors, Catalina Island, CA 90704Facilities include lecture hall, wet/dry labs,dormitory, cafeteria, apartments, boats, divelocker. There is immediate access to a richmarine flora and fauna. A fast commercialboat serves the island from San Pedro, CA.FacultyDrs. Clifford Brunk Leonard Muscatine

David Chapman and visiting faculty.Elma Gonzalez

FeesTuition (UCLA credit 12 units)

$470 (California resident)$1902 (non-resident)

Room and board at CMSC$1150

Intended for BeginnersNo previous experience in molecular biology isrequired or expected, but basic background incell biology and biochemistry is assumed. Thecourse will include lectures, seminars, fieldand laboratory exercises and independentresearch projects. Emphasis will be placed onlearning advanced techniques. These willinclude aseptic innoculation, growth ratemeasurement, nutrient analyses, gas fluxes,chromatography, HPLC, gel electrophoresis,enzyme assays, ultracentifugation, proteinpurification, antibody preparation, western blot-ting, immunostaining, fluorescent antibodydetection, isolation of organelles and nucleicacids, restriction endonuclease analysis,Southern blotting and hybridization, nucleotidesequencing, preparation of gene probesand construction ofgenomic libraries. Tech-niques will be applied exclusively to marineorganisms.

Intensive Hands-on Laboratory ExperienceThis 10-week course is intended to trainmarine biologists to become versatile in tech-niques of cell and molecular biology and bio-chemistry. Preference will be given to graduatestudents in marine sciences.

ONR Fellowshipsavailable on a competitive basis.

For Applications & Information Contact:Department of BiologyUCLA, Los Angeles 90024(213) 825-3481Application deadline:December 16, 1988Late applications may be reviewed

> - ~~~~~~LosAngeles

Santa CatalinaIsland W 1

119W 118W

Department of Biology UCLA

Graduate Training Course

Marine Molecular BiologySponsored by the Office ofNaval Research

L

POSITIONS OPEN

COGNITIVE SCIENTISTThe Department of Psychology of the University of

Minnesota is seeking applications for a tenure-trackposition in cognitive science, at the assistant professoreveL The applicant should have a Ph.D. and demonstrat-ed competence in both computational modeling andempirical research. The individual should be qualiied toteach graduate and undergraduate courses in cognitivescience and would be expected upon hiring to initiate anactive research program. Preferred specialzation is in thearea ofcomputational vision, particularly in the interfacebetween lower and higher leve vision but candidateswith strong research credentials in other areas of cogni-tive science are also encouraged to apply. This is a facultyposition, 100% time appointment during the academicyear, with the initial appointrnent to begin 16 September1989. Salary is competitive and will depend on thecandidate's qualifications and experience. The Universityof Minnesota is an Equal Opportunity Employer and Educatorand specifically invites and encourages applications fiom womenand minorities. Candidates should submit curriculum vi-tac, at least three letters of refcrence, recent publications,and a statement oflong-term research interest to: Cogni-tive Science Search Committee, Psychologe Depart-ment, Universi of Minnesota, 75 East River Road,MinneapoLis, MN 55455.

Application deadline: 1 December 1988.

DIRECIOR. The Thomas Burke Memorial Wash-ington State Museum, University ofWashington, seeks ascholar in a relevant academic discipline with extensivemuseum experience and demonstrated research, teach-ing, and development skills to scrve as director. As thestatc's oldest and largest natural history institution, theBurke Museum emphasizes a acific im perspective;contains significant anthropological, geological, and zoo-logical collections; and, maintams active research, exhibi-tion, and public service programs. The museum is anacademic unit ofthe Collegc ofArts and Sciences and thedirector reports to the Dean. Applicants should have asubstantial background in muscum management and theacademic qualifications appropriate for appointmcnt atthe rank of professor in a University of Washingtondepartment. A letter of interest, curriculum vitae, and atleast four references should be sent to: Professor Ste-phen Porter, Chair of the Burke Museum DirectorSearch Committee, Geological Scicnces AJ-20, Uni-versity of Washington, Seattle, WA 98195. Nomina-tions received prior to 1 December 1988 and applica-tions submitted prior to 15 December 1988 will receivepnority consideration. The University of Washington is anEqual Opportunity/Affirmative Action Employer.

HARVARD MEDICAL SCHOOLDIRECTOR OF

THE ANIMAL RESOURCE CENTERSThe Director of the Animal Resource Centers (ARC)

will be responsible for overall management of veterinarycare and animal husbandry, long- and short-range facili-ties and financial planning, billing, purchasing, manage-ment information, personnel and related functions. TheDirector will become a major participant in the expan-sion and management of new animal care facilities, andwill supervise the professional staffofthree veterinarans,an Associate Director of Animal Care, and a supportingstaffof approximately 36. The Director will report to theAssociate 7Dean for Business and Finance.A D.V.M./V.D.M. from an AVMA-accredited institu-

tion is preferred. A Ph.D. with significant animal caremanagement experience would be an acceptable alterna-tive. Minimum of 3 years ofexperience manig financeand personnel im a complex operation, preferrably oneinvolving animal care is required. Applicant must havedemonstrated negotiating, managerial and communica-tion skills as well as an ability to design, develop andimplement administrative procedures and laboratory ani-ml training programs. Pamiliarity with an acadeuicmedical environment required.

Interested individuals should send r6sumd, curriculumvitae, professional qualifications, salary requirements,and a etter outdining their views on management of acentral animal resource facility to: Mr. John M. Deeley,Associate Dean for Business and Finance, HarvardMedical School, 25 Shattuck Street, Boston, MA02115.

Harvard Medical School is an Afirmative Action/EqualOpportunity Employer. Female and minority candidates areencouraged to apply.

DEAN OF SCIENCEBIOLOGY/SCIENCE EDUCATION

DEAN OF SCIENCE: 12-month contract-$64,812. Contact: Dr. Nancy Grayson, Department ofEnglih.eparnment of Biology announces tenure-track, entrv

lcvel positions at rank ofASSISTANT PROESSORIstarting fall 1989; Ph.D. required. Successful candidatesmust have strong commitment to xccllence in teachingand mntenance of a productive research program,induding grantsmanship and supervision of graduatestudents, in the sp ed field.Limnology: Modeling and plankton experience with

chemistzy backgound preferred. Research program inlimnology and water quality, teaching in limnology andintroductory biology. Contact: B. G. Whiteside.Aquatic Ecolo: Background in aquatic ecology and

specialization in aquatic invertebrates preferred. Teach-ing in aquatic biology, ccology, and introductory biolo-gy. Contact: B. G. Whiteide.

Science Education: Minimum of 3 years ofsecondaryschool teaching experience required with backgound inphyical and earth sciences. Teaching and general sciencefor future elemcntary teachers, secondary science meth-ods, laboratory coordination, and supemsion of studentteachers seeking state certification at secondary level.Contact: M. Lewis.ASSISTANT PROFESSORSHIPS: One or more

nontenure-track, 1-year positions with possible renewalfor 1990 to 1991. Contact: E. L. Schneier.

Application deadline is 10 January 1989 for tenure-track positions; 6 March 1989 for 1-year positions. Sendcurriculum vitae, publications, official graduate/under-graduate transcripts, and names ofthree references to theappropriate contact person at the following address:Sa Committee, eparment of Bioloy, South-west Texas State University, San Marcos,TX 78666.The University reserves the right not to proceed with anyappointennt for financial or programmatic rcasons. AnEqual Opportunity/Afirmative Action Employer.

DIRELECTOR,COASTAL FISHERIES INSTITUTELOUISIANA STATE UNIVERSITY

The Coastal Fisheries Institute (CFI) of LouisianaState University's Center for Wetland Resources is seek-ing applicants for the position ofDirector. Established in1982, the CFI conducts fundamental and applied re-search rdelvant to manne fisheries ofthe northern GulfofMexico. Its multidisciplinary staff has grown to ninePh.D.'s, one J.D., and fifteen research associates andindudes fishenes saentists with various interest fields, amarine economist and a fisheries attorney. Ph.D. infisheries, marine sciences or related area is required. TheDirector's position will be at the fill or associate profes-sor level and tenurable through the Department ofMarine Sciences. Althougt finalhiring approval is pend-Sng a hiring date of 15 August 1989 is anticipated.

ary is commensurate with qualifications and experi-ence. Applicants should send curriculum vitae, names,addresses, and telephone numbers of at least three refer-ences, and a statement of research goals to: Dean,Center for Wetand Resources, Louana State Uni-versity, Baton Rouge, LA 70803-7503. Applicationswill be accepted until 15 January 1989 or until a suitablecandidate pool is established. LSU is an Equal OpportnityEmployer.

THE NATURE CONSERVANCYFOUR KEY POSMONS

DIRECTOR OF BIOLOGICAL MANAGE-MENT. Responsible for scientific aspects of the world'slargest system of privately owned nature preserves. Dc-sign, implement, and manage biological monitoring,research and preserve design programs. Location: Ar-lington, Viriiia.REGIONAL DERECTOR OF STEWARDSHIP

(three positions). Manage biological monitoring, re-sarch, preserve design, and land management programsin a 12-state region. Help recruit and train land manag-ers. Locations: Minneapolis, San Francisco, and ChapelHill.Advanced degree, experience inma t of rare

species and natural arcas or biological inventory methodsrequired. Submit rdsumEs to: John W. Humke, VicePresident, Direor of Stewardship, Ihe Nature Con-servancy, 1815 North Lynn Street, Arlington, VA

An Equal Opportunity/Affirmative Action Employer.

DIRECTOR OF RESEARCHThe National Undersea Research Center at Fairleigh

Dickinson University (NURC-FDU) seeks a dynamicindividual for its St. Croix, U.S. Virgin Islands facility.With expansion plans for science and technology researchin the marine environment, NURC-FDU seeks a versa-tile scientist with a record ofresearch, administration andmanagerial accomplishment and proven leadership inter-est. Primary responsibilities will indude overall planning,developing and administration of the research jrograms,coordination of interdisciplinary subcontracted resarchand exploration of new fields of inquiry. The directorshoiud have current research knowledge in his field.Salary will be consistent with achievement and back-ground. Interested individuals should submit their cur-riculum vitae or resume by 6 January 1989 to:

Chairman, Search CommitteeNational Undersea Research Centerat Fairlcigh Dickinsn Univcrsity

40 Estate Castlc CoakieyChritiansted, St Croix

U.S.V.I. 00820Fairleigh Dickinson University is an EqualOpportunity/Afirmative Action Institution.

WASHINGTON STATE UNIVERSITYCOLLEGE OF PHARMACY

DISTINGUISHED PROFESSOR OFPHARMACEUTICAL SCIBNCES

A permanent, fill-time position at the rank ofassociateor fill professor is available 1 June 1989. The Distin-guished Professor is expected to initiate and maintain astrong self-sustaining research program in the pharma-ceutical sciences. The incumbent will contribute to theprofessional and graduate programs of the College ofPharmacy and participate inother research, educationaland service activities of Washington State University.Qualifications for the position indude: Ph.D., a mini-mum of 5 years of experience in biomedical research, astrong record of research accomplishments, and a sus-tamed emramurally funded independent rearch pro-gram. Preference will be given to applicants who have aprofessional degree in pharmacy or experience in phar-macy education, and who have research interest andecperience in the study of molecular m nisms ofbiological responses induding computer aided dmg de-sign. Letters of nomination or application, a currentrsuin, and names, addresses, and telphone numbers ofat least three references should be sent ore 1 February1989, to:

William L. Hayton, Ph.D.Chair, Search Commit Distiguished Professor

ColDige ofPhWashingon Sate Un ritPullman,WA 99164-6510

WSU is an Equal Opportunity/Afinmative Action Eduatorand Employer. Protected group members are wnuraged toapply.

ENDOCRINE ASSAY LABORATORY MAN-AGER: Position available immediately for experiencedendocrine technician (B.S./M.S.) with man entexperience. Located in rural Piedmont of Blue RidgeMountains. Duties include personnel supervision, bud-getary management, development/application oftechnol-ogy and quality control. Experience with immunoassay,radioiodination, steroid technology, ligand binding as-says, and bioassays desirable. Contact:1Dr. Don Korit-ni, Dertment of Comparative Medicine, BowmanGray School of Medicne, 300 South HawthorneRoad, Winston-Salem, NC 27103. Afirmative Action/Equal Opportunity Employer.

ENGINEERING OPPORTUNITESCollier County seeks degreed engineers for positions

in their Public Works, Utities andCommunity Devel-opment Divisions. Join our growing organization andenjoy a satisfying living and working environment inbeautiful Naples, Florida. For specific job titles, call ourJobs Available Hotine at 813-774-8112, or for fur-ther considerations, send your r6sum6 with salary re-quirements by 1 January 1989 to: Collicr Count1Government, Human Resources Departmcnt, 330East Tamniami Trail, Naples,FL 33962. Equal Opport-nity Employer. Veterans and their spouses may receive prefer-ence in employment and are encouraged to apply.

SCIENCE, VOL. 2421078

POSITIONS OPEN POSITIONS OPEN

DIRECTOR,MEDICAL

TECHNOLOGYWe are an expandingCincinnati-based, privatecompany which invests in,develops and manages med-ical technology ventures.

We are seeking a broadlyknowledgeable individual toestablish and direct the activi-ties ofourcompany relative tothe evaluation, acquisitionand development of emerg-ing medical technologies.Reporting directly to the VicePresident of Business De-velopment, you will forecasttechnological trends and pro-pose technology direction andstrategy for the company; youwill research and evaluatepotential investments in awide array of technologies formedical applications; andultimately you will providetechnical and clinical consul-tation and direction for themultiple business ventures ofthe company.

If you are the person we seek,you have the intellectual curi-osity, confidence and capabil-ity to identify, synthesize andcommunicate the key ele-ments and status of anyphysical and life sciencestechnology; you haveknowledge of FDA interfacesand clinical investigationmanagement, with strong tiesto the public and private med-ical research communities;and you have distinguishedacademic and professionalaccomplishments which am-ply demonstrate your excep-tional management andtechnical capabilities.

If this sounds familiar, wewould like to talk to you aboutan opportunity... an opportu-nity to fully apply your uniquecapabilities in an attractive,knowledge-based environ-ment as part of a creativemanagement team.

We have the right compensa-tion and benefits packageawaiting the right person.Please contact us with a letterand resume in confidence to:

BOX 171, SCIENCEEqual Opportunity Employer

HHMI-NIH Research Scholarsat theNational Institutes of Health

The Howard Hughes Medical Institute (HHMI) and the NationalInstitutes of Health are accepting applications for the 1989-1990class of Research Scholars to begin in the summer of 1989.

* HHMI-NIH Scholars are selected from medical schools, usuallyafter the first two years, for a year of laboratory research at theNIH in Bethesda.

* Scholars must be U.S. citizens or permanent residents attendingmedical school in the United States or Puerto Rico.

* Scholars are paid as employees of HHMI and housed on theNIH campus.

* Applications must be received by January 15, 1989.Candidates will be notified of results by April 1, 1989.

* Application kits and brochures have been sent to the deans'offices of all medical schools. Additional kits and brochures canbe obtained from:

Howard Hughes Medical Institute1 Cloister CourtBethesda, Maryland 20814-1460(301) 951-6710

HHMI is an Equal Opportunity Employer.

Howard Hughes Medical InstituteAnnounces a New Program

Medical Student Research Training FellowshipsThe Howard Hughes Medical Institute will award up to 60 fellowshipsto medical students who wish to spend a year in intensive research duringthe 1989-90 academic year.

Eligibility:* Applicants must be attending a U.S. medical school, but there are

no citizenship requirements.* The fellowship research may be undertaken at any academic or

research institution in the United States.* Students enrolled in M.D./Ph.D. programs are not eligible.* Applicants may not apply simultaneously to the HHMI-NIH

Research Scholars Program.Fellowship Awards:

* $12,300 stipend.* $7,700 allowance to the fellowship institution for research supplies

($4,000) and institutional expenses ($3,700).Deadlines:

* January 13, 1989, for completed applications.* Awards announced by early April 1989.* Fellowship tenure must begin by October 1989, at the latest.

For information:Call (301) 571-0324or write:

Medical Student Research Training FellowshipsOffi'ce of Grants and Special ProgramsHoward Hughes Medical Institute6701 Rockledge DriveBethesda, Maryland 20817

The Howard Hughes Medical Institute welcomes all qualified applicantsand encourages women and members of minority groups to apply.

n

LLLJ

POSITIONS OPEN

ECOLOGY AND EVOLUTIONThe University of Iowa's Department of Biology is

currently reviewg candidates for appointment at theassistant and associate professor levels. Our searh is nowexpanded to indude the PROFESSOR level. We willconsider oustanding scholars and leaders enggd inheoretical or experiental analyses of any major prob-ems in ecology or evolution. Applicants should submiturriculum vitae, statemnt of research interests andshould arrange for at least thrce reference letters to besent to: Professor Richard V. Bovbjerg, The Universi-t of Iowa, Iowa City, IA 52242. Telephone: 319-335-1073.

The University of Iowa is an Equal Opportunity andAfirmative Action Employer; we encourage applications fromwoman and minorities.

ENDOCRINOLOGY AND METABOLISM-Two positions (Ph.D. or M.D.) to join a multidis-ciplinary rcesarch grop in diabetes and obesity areavailable immediatel.Interest could include in vitrometabolism in human hepatocytes, adipocytes and mus-de fibers; insulin signals; insulin receptors stucture andfunction; assessment in vivo insulin action and metabo-lism in man using isotopes; application of moleculargenetic techniques to the etiology and pathogenesis ofdiabetes. Please send curriculum vitae to: Jose F. Caro,

MD., Dept of M e d ig, EDastCaroliia TJnmrsty School ofM , Genville,NC 27858. An Equal Opportunity/Affirmative Acion Em-ployer. Federal law reqiresproperdocumntation ofidentity andemployability at the time of employment. It is requested thisdocumentation be induded with your application.

ENVIRONMENTAL HEALTHThe Program in Social Ecology at the University of

California, Irvine, is rciting for an ASSISTANTPROFESSOR, tenure-track, position in the area ofenvironmental health. Ph.D. in environmental sciences,organic chemistry, molecular genetics, or biochemistry ispreferred with experience in laboratory of field researchrelated to environmental health sciences. Ability to teachstatistics and environmental testing methodology is de-sirable. Please send cover letter, curriculum vitac, andnames of three referees to: Dr. Betty H. Olson, vi-ronmental Healtl Search C t , Proram inSocial Ecology, University of California, Irvine, CA92717, by 1 JanuLary 1989. UC is an Equal OpportunityEmployer/Afirmative Action Employer.

EVOLUTIONARYBIOLOGIST. The Departmentof Biology, University ofNorth Carolina at Chapel Hill,seeks an outstnding saentist investating evolutionarymechanisms at the population level. The appointment toenhance our program in ecology, behavior, cvolution,and organismic biology will probably be made at therank ofasistant or associate profcssor, alhough all levelswill be considered. Appointment will begin in July 1989or later at the evidence of the appointee. Applicantsshould send curriculum vitae, a description ofresearchinterests, selcted publications and four letters of recom-mendation by 1 arch 1989 to: Evoludonar BiologSearch, Depatm of Bio , Unimrsity of NorhCarolina, Chae l, NC 2X99-3280. The Universi-ty of Nort Carolina is an Equal Opportunity/AfirmativeAction Employer and encourages applicationsJfom women andminorities.

The Department of Surgery, University of NorthCarolina School of Medicine, is seeking a fu-timeFACULTY MEMBER who has completed his/hergraduate education in general surgery and who hasmoated ability as a teahcr and clinician. Academic

rank is dependent upon qualifications of individual. Thesuccessful applicant should have completed fcllowshiptraining in surgical oncology. He/shc should have aspecial competence in tumor Immunology with the abili-ty to carry out basic and clinical investigations in thisfield. Interested applicants should foiward their curricu-hlm vitae and bbliography to: George F. Sheldon,M.D., Chairman,D t ofSWgry, U tyof North Ca , 136 Burnett-W a Builing229H, CB, #7050, Chapel Hill, NC 27599. TheUniversity of North Carolina is an Equal Opporunity/Affir-matve Action Employer. Minorit and female applicants areencouraged to voluntarily identfy themselves.

POSITIONS OPEN

Dickinson College. The Environmental Studies Pro-gram invites applications for a fiu- ume, teure-trackFACULTYPO)SJON beginning in September 1989.We seek a canddate with a background in one or more ofthe natural sciences, iterdisciplinary expeience andinterest induding environmental policy analyis. Appli-cants should submit curriculum vitae and three let ofreference by 1 February 1989 to: Dr. Candie Wllder-man, dintor, Eiment S P ,Dickinon Cofleg, Carlise, PA 17013. AjlrmativeAction/Equal Opporunity Employer.

Emory University, Department of Radiology, soeks aPh.D. or M.D. with cither NMR spectrosco or -ing experience for a full-time FACtJLTY POsmOR.The candidate must be able to ognate fudable re-search projects using NMR and collaborate with odterfaculty mcmbers (in or out of radiology) on NMRresearch. Knowledge of spin behavior is essential, andmedicinc, biology, or biochemistry, analog ectronics,and computer scence arc useful sklls.Two 1-meter clinical imagers operating at 0.5 and 1.5

T and a 30-cm 200 MHz instrument, alI fuly prgram-mable, will bc available. The deparmet is part of an800-bed ternary care complex giving ample opportunityfor collaborations requiring clinical material. SevenPh.D. scicntists in the radiologydeparment are currentlyinvolved, full-time, in NML& Qualfied candidates pleasecontact:

Dr. Thomas Dixon, DirectorFrits Philips ntc R nce

419 Woodruff Memorial BuildingUmry niveI

, GA 3032Emory University is an Equal Opportunity/Afirmative

Adion Employer.

FACULTY POSMON IN BIOPHYSICSAT HAVERFORD COLLEGE

The Deparmnt of Physics invites applications for aspeial assistant or associate professorship in biophicsfor a period of up to 4 years. Applnts must have aPh.D. and- be strongly motivated toward creative re-search and undra ate teaching. The successfid candi-date will assist m deveoping a new intcrdi sbiophysics program. Subsal startup funds rre-search are available. The position is part of a majorprogram funded by the Howard Hughes Medical Insti-me to enhanc te biological sciences through interac-tion between the varu scece deparm .

Haverford is a liberal arts collge wit an internationalreputation for stresea andinsuction in thephysical and life scine. We have active collaborationsIn the scinces with the University ofPennsylvania, BrynMawr College, and Swarthmore, among others. Pkasesend curricuhum vitae, list ofpublications, a statment ofresearch interests, and at kast ree letn of r -dation by 16 January 1989 to; Profsor David Pine,Department of Physics, Haverfird College, Haver-ford, PA 19041. An Equal Opportunity/Affirmative ActionEmployer.

FACULTY POSMONSAdanta University invites applications for tenure-track

faculty positions at the assistant or associate professorkevel. Postdoctoral training is expect Positions areavailable in the Depatment of Chemisty in the area ofbiochemistry and m the De t of Biolgy in thearea of the ccllular and molcular aspect of develpmental biology or molecular biology. Su candi-dates are expected to maintain an independent vigorousresearch program and be dedicated to grduate andu rgrau iru on. All candidtes hould sendcurriculum vitae, representative publications, a brief re-search prposal and have three l of recommenda-tion sent to: Dr. Frank Cumminp, Assodate Dean ofArts and Sciences, Atlanta UnIersity, Atanta, GA30314 by 23 Dember 1988.Adat Universtiy is an Equal Opportunity/Afirmtave

Action Employer.

POSITIONS OPEN

DEPARTIMENT OF BIOLOGYFACULTY POSMON IN

BIOCHBEMISRYMASSACHUSETrS INSTITUTE

OF TECHNOLOGYCandidates are sought for a posinon in the field of

biochemistry.Candidates should have significant research experience

in the area of biocheniustry of proteins, enzymes, nudeicadids, or membranes. While a broad latitude in researchinterest will be considered, we are particularly interestedin canddates ngaged in studies on chemistry, structure,and mechanismn oaction of biological molecules.

Responsibilities associated with this position indudemaintaining an active research program and participatinginthe teaching program of the department.

Applicants should send curriulum vitae and a summa-ry ofproposed research, and arrange to have letters fromat kast three scientists who can provide an evaluation ofthe candidate's accomplishments and fiture potential.Appicants should be sent to:

Professor Uttam IL RajBhandayChairman, Biochemist Search Cmmittc/o Biology Headquarters, Room 56-511Massachett Insiute of Technolog

CambridgMA 02139An Equal Opportunity/Affirmative Action Employer

FACULTY POSION INBIOMECHANICS/NEUROSCIENCE

Twelve-month, tenure-track appointment. Responsi-bilities indudc baccalaureate and graduate level teaching,research and service. Opportunity to interact with bioen-gineering and conduct research in laboratory equippedfor meaurement in EMG, torquc, motion, and groundreactions; analyses via computer and on-line i nsystem. Minimum requirements are 3 years of cliicalexperience, licensure or eligibility in Kentucky, and aPh.D. Opportunity to work cinically, in OutpatientUniversity Hospital rehabilitation centcr. Applicationswill be acccpted until position is filled. Send ktter ofapplication, curriculum vitac, and names of three refer-ences to:

Dean P. Currier, P.T., Ph.D.Division of Ph dical Iherapy

Unvriyof KentukyMedical CentcrAnnex I, Room 4

io n, KY 40536-0079Equal Opportnity Employer.

FACULTY POSMONSDEPARTMENT OF BIOCHEMISIRYAND MOLECULAR BIOLOGY

The E. A. Doisy Department of Biochemistry andMolecular Biology at St. Louis University intends tomake two fculty appointets at the jumor or seniorlevel tos current exptruse in the folloinareas: PROTIN STRU U AND UNCTIOXindividuals with research experience and interest ibthemechanisms ofezyme catasis, protein-prtein and/orprotein-muscle acid c iton, and allo icffe areencouraged to apply for this positon CElLULAREGULATION individuals with resach iand itrs in membrane biodchmistry andbiosynthesis of membrane lipids and carbohydrates, or-ganelle biogenesis and transport mechanisms are encour-

too ap Iyfor thisposition. Of particular interest arei?e app who combine classical biocheistr andmodemr strategies in an naive inden t reecprogram. Successful1 candidates will complent iIng resarch in the areas of metabolism a rglion,molecular and developmental biology, g c dll biol-ogy, and physical biodcheistry and can particpate in themukidepar tnta cel and numlcular biolgy program atSt. Louis University School ofMedicin elet start-up finds and salary are available. Curriulum vitae,desription of research plans, and at leasi three letters ofrccommendation should be set by 1Februars 1989 to:Search Co ms c/ Dr. LWilam Sl Chair-man D t of Bichemi MlBiology, SL Louis University School of ee,1402 South Grand Boulevard, St. Louis,MO 63104.St. Louis University is an Equal Opportnity/AffirmativeAction Employer.

SCIENCE, VOL. 242

II

I080

PhD, BS, MS ResearchStaff MembersLawrence Livermore National Laboratory, located in the San Francisco Bay Area, is seeking ap-plicants for ten different positions including postdoctoral appointments, term appointments and careerstaff in the Biomedical Sciences Division.

All candidates must have adegree (BS, MS or PhD for different positions) preferably in MolecularBiology, Biochemistry, Biophysics, or Genetics. Experience in one or more of the following areasis desirable: nucleic acid chemistry, nucleic acid electrophoresis, in situ hybridization, molecularcloning in cosmids or yeast artificial chromosomes, analytical chemistry, immunochemistry, fluores-cent methods for DNA labeling, biochemistry of DNA repair, cytochrome P450 analysis.

Openings are available in:

Molecular BiologyA team research effort to order, map and sequence components of the human genome.* Development and applications ofclonefingerprintinglwalking strategies, large fragment mappingby pulse-field electrophoresis, or development ofvector-host systems to clone large pieces of DNA,or rapid, novel methods of DNA sequencing.

Molecular analysis of human mutations (either somatic or heritable).* Genetics, molecular biology and mutagenesis of humans using DNA restriction, phage/cosmidcloning, nudeic acid electrophoresis, in situDNA hybridzation, and enzymatic ampliffication of DNA.

Multidisciplinary effort to understand human DNA repair.* Emphasis is on expression of cloned human repair genes and biochemical analysis of theirproducts.

Biochemical ToxicologyAnalysis of human metabolism of dietary mutagens and carcinogens.* Develop immunochemical and analytical chemical methods for detecting urinary metabolites,carcinogen-protein adducts and carcinogen-DNA adducts. Experience with P450 metabolizingenzymes, aromatic amine toxicology, in vitro neoplastic transformation or immunochemicalmethods is desirable.

BiophysicsLarge scal efbrts to improvein situ hybridization with nucleic acid probes and to classifyand purify nucleicacid probes according to size and DNA sequence.* Emphasis will be on the application of novel biophysical techniques and robotics. A background inbiophysics or biomedical engineering and an interest in automation is helpful.

We offer a highly competitive salary and benefit package. Send curriculum vitae to Earl G. Morrell,Personnel OperatIons Dhvision, Lawrence Uvermore National Laboratory, P.O. Box 5510, L-725, Dept.KSCBI802B, Uvermore, CA 94550. U.S. Citizenship Required. Equal Opportunity Employer.

Universityof California

Lawrence liv eV. National Laboratory

Manager, ProteinPurificationOncogen, a division of Bristol-Myers and a leaderin biotechnology, performs research dedicated topursuing novel approaches to the development oftheraputic products in the area of immunology,infectious diseases and cancer.

We are recruiting for a PhD in Biochemistry with 2-5 years of protein research experience to set up andmanage an effort providing pure proteins for clin-ical trial use. The successful candidate will have re-

sponsibility for the development of procedures,equipping the laboratory, directing others in thepurification of recombinant proteins produced bymammalian cell culture, development of noveltechnology for protein purification, investigatingformulation and stability of proteins, and analysis ofprotein structure.

Oncogen offers a stimulating scientific environmentand excellent compensation and benefit packages.For consideration, send a curriculum vitae to:J. McGough, Oncogen, 3005 First Avenue,Seattle, WA 98121. EOE/AAP.

ALZA is making adifference in the worldof medicine...

You can make a difference at ALZA

IRRITATION RESEARCHApplications are invited for the position of ResearchScientist in our Biological Sciences Group. You willinitiate and perform research on the problems oftissue irritation (mainly GI and cutaneous); evaluaterelevance of current in vit and in viw models in use

at ALZA; and establish expertise applicable to all newareas of research where irritation is likely to be ofconcern, including transdermal, electrotransport,peptide delivery and parenteral delivery.PhD in relevant biological science with post-doctoralexperience and proven ability to independentlyconduct research are required. Applicant must haveexperience in a research field with relevance toirritation biology, such as the study of microvascularpharmacology or biology. Experience in electrophysi-ology would be desirable.To apply, please send your resume to: DarleneMarkovich, Director of Employment, ALZA Corpora-tion, 950 Page Mill Road, P.O. Box 10950, Palo Alto,CA 94303-00. We are an equal opportunityemployer.

ala

POSTDOCTORAL POSITION

Available to study protein secretion fromgram-positive bacteria (lactic strepto-cocci) at the Biotechnology Department ofCIBA-GEIGY in Basle, Switzerland.Applications including curriculum vitae, adescription of research, the names and ad-dresses of three references from whom wemay request letters of evaluation should besent under ref. "Science 952" to Dr. W.Reber, CIBA-GEIGY Ltd, Personnel Depart-ment, Postfach, CH-4002 Basle.

CIBA GEIGY

GRADUATE PROGRAMCELL AND MOLECULAR BIOLOGY

(MULTI-DEPARTMENTAL)

* GENE REGULATION* MOLECULAR GENETICS* DEVELOPMENTAL BIOLOGY* ONCOGENES AND GROWTH FACTORS* STRUCTURAL BIOLOGY* NEUROBIOLOGY* MOLECULAR VIROLOGY AND IMMUNOLOGY

The Graduate School at BAYLOR COLLEGE OFMEDICINE has recently created a graduate program inCELL AND MOLECULAR BIOLOGY stressing basicresearch in the above areas. Studeilts accepted forstudies leading to the Ph.D. degree will receive financialsupport. For further information contact:

Dr. Savio Woo, DirectorGraduate Program in Cell and Molecular BiologyBaylor College of Medicine, Room 1 85AOne Baylor PlazaHouston, Texas 77030Phone: (713) 799-6557

mobilr: ::X

jav.X:

Senior ResearchEntomologist

Agricultural ResearchThe Agricultural Research depart-ment of the Merck Sharp & DohmeResearch Laboratories located inThree Bridges, New Jersey, is seekinga Senior Research Entomologist in-terested in field research and develop-ment of agricultural pesticide pro-ducts. The candidate will be responsi-ble for establishing and monitoringfield trials, reviewing efficacy data,and making recommendations tomanagement regarding productdevelopment.The position requires a Ph.D. degree orequivalent in entomology or relatedscience with 2-3 years relevant ex-perience. The successful candidatemust have a good working knowledgeof insecticides, economic entomology,and pest and disease control.The Three Bridges Facility is located inHunterdon County in West central NewJersey.

Salary and benefits are excellent.Please send resume to Ms. Delores L.Barefield, Merck Sharp & DohmeResearch Laboratories, P.Q Box 2000,WBD-362, Rahway, New Jersey 07065.

Equal Opportunity Employer

KE

DIRECTORCARDIOVASCULAR/

PULMONARYRESEARCH INSTITUTE

Deborah Research Institute has aposition available for Ph.D. withbroad research experience to serveas Scientific Director of our cardio-vascular and pulmonary institute.The successful candidate shouldhave experience with myocardialprotection, new perfusion methods,left-ventricular assist devices, lasersurgery, heart transplantation re-search or valve and blood vesseltransplantation research.

In addition, the candidate will beable to bring about a balance be-tween basic and clinical research,as well as direct efforts in extramu-ral grant writing, grant distributionand the direction and planning ofthe scientific activities of ourinstitute.We adjoin Deborah Heart and LungHospital. For confidential consider-ation, please forward your resumeto: Chairman of the Board

DEBORAH RESEARCHINSTITUTETrenton Road

i . Browns Mills, NJ 08015Equal Opportunity Employer

NATIONAL UNIVERSITY OF SINGAPOREINSTITUTE OF MOLECULAR AND CELL BIOLOGY

Applications are invited from suitably qualified scientists at the level of principalinvestigators to join the Institute of Molecular and Cell Biology. The Institute, operationalsince the end of 1987, consists of the Cell Regulation, the Infectious and GeneticDiseases and the Plant Genetic Engineering Groups. It provides comprehensive supportfacilities including capital equipment, substantial operating and conference expenses,supporting staff at the pre- and post-doctoral levels and laboratory space ranging from500 to 1000 square feet.Applicants should have experience in one of the following fields: yeast genetics,molecular virology, molecular basis of genetic disorders, developmental biology,cellular immunology, biochemical virology, cytokines and immunohormones.

Salaries will be competitive and commensurate with experience, including excellentfringe benefits. Applicants should send their curriculum vitae and addresses of 4referees to the:

DirectorPersonnel DepartmentNational University of Singapore10 Kent Ridge CrescentSingapore 0511

Enquiries may also be sent through BITNET to:

PERSDEPT @ NUSVM

BIOMEDICAL SCIENTIST!CELL BIOLOGISTThe Research Division of W.R. Grace & Co., a Fortune 100 Company inthe specialty chemical and health care arenas, has an excellentopportunity in its Biomedical/Biotechnology Research Program.As part of a multidisciplinary team, you will conduct researchdeveloping new technologies and products relating to mammaliancell culture systems, hybrid artificial organs, hemoperfusion systems, andspecialty biochemicals.This position requires an M.S. or Ph.D. in Cell or Molecular Biology,Pharmacology or Biomedical Sciences with experience in mammaliancell culture and cell modulators.Grace offers an attractive salary, an excellent benefits program anda rewarding, growth-oriented career. We actively encourage thepublication of technical papers. We are located in the picturesquecommunity of Columbia, Maryland, close to both Baltimore, Marylandand Washington, D.C.Please send your resume in confidence, including salary history to:Mana,aer, Employment

Deofent MCW.R. Grace & Co.Washington Research Center7379 Route 32Columbia, Maryland 21044

GRACEAn international specialty chemical company withselected interest in energy, manufacturing and

service businesses.

An Equal Opportunity Employer M/F/H/V

AMMON'AMWr

POSITIONS OPEN

FACULTY POSMON INPLANT PHYSIOLOGY

The Department of Botany, University of Iowa, in-vites applications for a tenure-track position in plantphysiology effective 1 July 1989. We seek candidateswhose research interests emphasize molecular/biochemi-cal approaches to fundamental problems in plant physiol-ogy. The position is approved at the assistant pro essorlevel, but applications from individuals with outstandingresearch records may be considered at a more senior levelPlease send a current curriculum vitae, reprints, a briefsummary of research goals, and three letters of referenceto: Professor Richard Sjolund, Department of Bot-any, University of Iowa, Iowa City, IA 52242.

The University of Iowa is an Equal Opportunity andAffirmative Acion Employer. We encourage applications fromwomen and minorities.

FACULTY POSITION, MICROBIAL PHYSI-OLOGY. The Department of Botany and Microbiologyat the University of Oklahoma invites applications for atenure-track appointment at the assistant professor level.Applicants should have a strong background in microbialphysiology, a Ph.D., and relevant postdoctoral researchexperience. The successful candidate will be expected todevelop and maintain a strong extramurally supportedresearch program in microbial physiology and to partici-pate in the undergraduate and graduate teaching pro-grams of the department. Preference will be given toapplicants who are able to apply modem methods ofmolecular biology in their research endeavors. Initialsereening of apcants will begin 10 February 1989 andcontinue until filled. Applicants should arrange for threeletters of reference to be submitted and mail curriculumvitae, a statement ofcurrent research activities, and futureresearch goals to: Dr. Joseph M. Suflita, MicrobialPhysiology Search Committee, Department of Bot-any and MIicrobiology, The University of Oklahoma,Norman, OK 73019. OU is an Equal Opportunity/Affirmative Aaion Employer.

DEPARTMENT OF BIOLOGYUNIVERSITY OF VIRGINIA

FACULTY POSITIONS at the junior or senior levelare available in the research group investigating basicmechanisms of biological rhythmicity. We seek appli-cants with research interests in circadian rhythms, neuro-nal oscillations, reproductive cydes or other aspects oftemporal organization, as well as expertise in a contem-porary biological field such as neurobiology, molecularne or cell biology. Successful applicants will com-

bine outstanding research accomplishments or potentialwith ability to contribute to the intellectual life of adepartment dedicated to the highest level of undergradu-ate and graduate education. Please send curriculum vitae,including a description of research plans and three lettersof reference by 1 February 1989, to: Michael Menaker,Chairman, Department ofBiology, Gilmer Hall, Uni-versity of Virginia, Charlottesvclle, VA 22901. EqualOpportunity/Affirnative Action Employer.

FACULTY POSITIONS INPLANT BIOLOGY ANDMARINE BIOLOGY

FLORIDA STATE UNIVERSITYThe Department of Biological Science will be expand-

ing faculty research strengths in two areas of organismalbiology: plant biology and marine biology. Recruitmentfor an ASSISTANT PROFESSOR in each of theseareas will be broadly based. Applications representing adiverse array of interests and isciplines are encouraged.We especially want faculty who will complement ourpresent strengths in ecology, evolution, and marine/aquatic biology. In addition to quality undergraduateteaching, faculty are expected to establish productiveresearch programs and to contribute to the professionaldevelopment of graduate students. Send a letter ofapplication, resume, statement of research and teachinggoals, and names and addresses of three references by9December 1988 to: Search Committee, c/o Dr. Law-rence G. Abele, Chairman, Department of BiologicalScience, Florida State University, Tallahassee, FL32306. The Florida State University is an Affirmative Action/Equal Opportunity Employer. Applications from women andminorities are encouraged.

FACULTY POSMON IN RADIATIONBIOLOGY AT STANFORD UNIVERSITYThe Division of Radiation Biology of the Department

of Radiation Oncology is seeking an associate professor(research) to complement existing programs in hypoxiccytotoxins and radiation sensitizers, hyperthermia, cellcycle and tumor biology, DNA repair and mutagenesis,and leukemogenesis. Areas of interest of applicant couldinclude oxygen measurement and transport, blood flowmodification, antibodies of tumor detection and treat-ment and cellular and molecular aspects of predictiveassays. Stanford University is committed to increasingrepresentation of women and members of minoritygroups on the faculty and particularly encourages appli-cations from such candidates. Applicants should submitcurriculum vitae and names of three references to: Dr. J.Martin Brown, Director, Division of Radiation Biol-ogy, Department of Radiation Oncology, StanfordUniversity School of Medicine, Stanford, CA 94305.

IMMUNOLOGIST-VIROLOGIST (search re-opened)-The Stephen F. Austin State University Biolo-gy Department invites applications for a tenure-trackposition of assistant professor. A Ph.D. with specialtiesm immunology and/or virology is required. Duties in-clude teaching immunology, virology and introductorybiology; research and publication will be expected. Salarycommensurate with training and experience. Duties be-n in August and closing date for application is 15ecember 1988. Send curriculum vitae including tran-

scripts and have three letters of recommendation sent to:W.V. Robertson, Search Committee Chairman, Box13003, SFA, Nacogdoches, IX 75962. An Equal Op-portunity/Afirmative Action Employer.

JUNIOR FACULTY POSMIIONS available in thePharmacology and Developmental Therapeutics of anti-neoplastic agents targeted for specific human cancertypes. Candidates should have the Ph.D. degree with aminimum of 3 years of postdoctoral experience in arelated field. The two programs are as follows:

1) Colon adenocarcinoma. The biochemistry andpharmacology of modulation of antimetabolites withthymidylate synthase as the primary target. Studies willfocus on biochemical approaches to modulate reducedfolate pools and to optize drug scheduling for thera-peutic gain. Research will also identify factors thatinfluence the regulation and turnover of thymidylatesynthase in elucidating the importance ofthe enzyme as atherapeutic target.Apply: Dr. J. A. Houhton. Salary negotiable.

2) Pediatric rhabdomyosarcoma. Drug targetingagainst differentiation antigens in tumors of skeletalmuscle. This will involve the molecular cloning of differ-entiation antigens together with their identification andcharacterization, and targeting drugs aga nst appropriateantigens in vitro and in vivo usmg anti es as carners.Apply: Dr. P. J. Houghton. Salary negotiable.Send curriculum vitae and names of three references

to: Laboratorics for Developmental Therapeutics,Department of Pharmacology, St. Jude Children'sResearch Hospital, 332 North Lauderdale, MemphisTN 38101. Equal Opportunity/Affirmative Action Employer.

Yale University/METAMORPHIC PETROLOGY.The Department of Geology and Geophysics invitesapplications for a JUNIOR FACULTY appointment in

toepic area ofmetamorphic petrology. We are particu-larly interested in field-based studies of regional-scalemetamorphism. Examples of research areas include thetectonic evolution of metamorphic belts, fluid and heatflow during metamorphism, physico-chemical and kinet-ic constraints on the history and evolution of metamor-phic rocks, and the chronology of metamorphic events.The appointment will complement existing programs instable isotope geochemistry, diagenesis, reaction kinetics,genesis of mineral deposits, fluid-rock interactions, tec-tonics of convergent margins, and processes of graniticmagmatism.

Applicants should sumbit a letter of application, cur-riculum vitae, publications, and the names and addressesof at least three references to: Dr. Barry Saltzman,Chairman, Department of Geology and Geophysics,Yale University, P.O. Box 6666, New Haven, CT06520. Completed applications must be received by 1March 1989.

Yale University is an Equal Opportunity/Afirmative ActionEmployer.

MAMMALOGY: ASSISTANT PROFESSOR,tenure-track position. Ph.D. and experience as fieldbiologist required. Teach mammalogy, freshman biolo-gy, and biometrics. Direct masters theses and seekfunding to support strong research program in regionalmammal populations. Send application with transcripts,curriculum vitae, statement of teaching and researchinterests, and three reference letters by 1 February 1989to: Dr. L. A. Jahn, Biological Sciences, WesternIllinois University, Macomb, IL 61455. Western IllinoisUniversity is an Equal Opportunity/Affirmative Action Em-ployer. Women, minorities, and handicapped persons are espe-cially encouraged to apply.

MOLECULAR BIOLOGISTThe Department of Biology ofPomona College invites

applications for a tenure-track, assistant professorshipbeginning fall 1989. Applicants should have a broadbackground in biology with extensive training in molecu-lar biology, including postdoctoral experience. Prefer-ence will be given to applicants with expertise in molecu-lar aspects of development and/or endocrinology. Theappointee will participate in an interdisciplinary molecu-lar biology program, supported by the Howard HughesMedical Institute. She/he will be expected to develop twoupper division courses in areas of specialization. Start-upfunds are available for the successlu candidate to estab-lish an active research program that can involve theparticipation of undergraduates. Send curriculum vitae,statements of research and specific teaching interests, andthree letters of recommendation by 31 December 1988to: Dr. Bruce Telzer, Search Committee, Departmentof Biology, Pomona College, Claremont, CA 91711.Pomona College is an Affirmative Action/Equal OpportunityEmployer.

MOLECULAR BIOLOGISTUNIVERSITY OF PITTSBURGH

SCHOOL OF MEDICINEThe Department of Pathology at the University of

Pittsburgh School of Medicine is seeking a molecularbiologist with a Ph.D. and postdoctoral training to joinits Clinical Molecular Biology Unit at the level ofassistant professor. A strong background in cloning andhybridization methods is desirable. Responsibilities willinclude the application of molecular techniques to thediagnosis of disease and development of an independentresearch program. Send curriculum vitae and three refer-ences to: Dr. Joseph Locker, Associate Director, Clini-cal Molecular Biology Unit, c/o A. Roman-Koller,University of Pittsburgh, School of Medicine, De-partmentof Pathology, 776 Scaife Hall, Pittsburgh,

MOLECULAR BIOLOGIST/MEMBRANE BIO-CHEMIST Brigham and Women's Hospital/HarvardMedical School is seeking scientists (Ph.D. or M.D.)with experience in biochemistry and molecular biologyof ion transport proteins. Successful candidates will joinestablished programs in membrane transport physiologyand cell volume regulation. Send statement of interests,full curriculum vitae, and names of three references to:Dr. B. M. Brenner, Director, Renal Division,Brigham and Women's Hospital, 75 Francis Street,Boston, MA 02115. An Equal Opportunity Employer.

THE COLLEGE OF STATEN ISLANDOF THE CITY UNIVERSITY

OF NEW YORKNEUROSCIENCE FACULTY POSITION

The College of Staten Island invites applications for afull-time tenure-track position (beginning 1 September1989) in developmental neurobiology. Candidates mustbe qualified to participate in the City University Ph.D.program in biology or biochemistry. A strong record ofresearch, publication and grant support is required. Rankand salary commensurate with experience and record ofscholarship. Salary range $30,000 to $65,000. Excellentfringe benefits, ample research space and start-up fundsare available. The successful candidate is expected toparticipate in the programs of the CSI/IBR center forDevelopmental Neuroscience. Send curriculum vitae andnames of three references by 16 January 1989 to: Dr.Barry Bressler, Vice-President for Academic Affairs,Thc College of Staten Island/CUNY, 715 OceanTerracc, Staten Island, NY 10301.

Equal Opportunity/Affirmative Action Employer.

SCIENCE, VOL. 242IO84-

POSITIONS OPEN POSITIONS OPEN

POSITIONS OPEN

MOLECULAR/CELLULAR BIOLOGISTIOWA STATE UNIVERSITY

Iowa State University invites applications at any levelfor a tenure-track or tenured faculty position. The suc-cessful applicant will be expected to lead a vigorous,externally funded research program involving state-of-the-art molecular, cellular and/or genetic approaches tostudy areas related to endocrinology such as: signaltransduction, control of secretion or the regulation ofgrowth and development. This position is part of amultimillion dollar, campus-wide effort to promote ex-cellence in molecular biology and biotechnology. Centralnucleic acid, protein, image analysis, fermentation, mo-lecular structure and cell-sorting facilities with the mostadvanced equipmcnt available have alrcady been estab-lished. Salary will be competitive and research start-upfunds of up to $150,000 are available. Teaching respon-sibilities will be modest. A description of research inter-ests, curriculum vitae and at least three references shouldbe sent to: Dr. T. Ingebritsen, Department of Zoolo-gy, Iowa State University, Ames IA 50011, by 15January 1989.

Women, minorities, and members ofother protectedgroups arestrongly encouraged to apply. Iowa State University is an EqualOpportunity/Affirmative Action Employer.

MOLECULAR GENETICIST. Fort Lewis CollegeBiology Department-molecular geneticist tenure-trackposition to begin September 1989. Teaching load williclude general biology, composition seminar, cell/mo-lecular biology, molecular genetics. Candidate must bededicated to liberal arts education. Send resume, threelettcrs ofrecommendation, and official transcripts to: Dr.Page Lindsey, Department of Biology, Fort LewisCollege, Durango, CO 81301. Screenimg will begin on9 January 1989. Fort Lewis College is an APrmative Action!Equal Opportunity Employer. Women and minorities are urgedto apply.

MOLECULAR IMMUNOLOGISTThe Rocky Mountain Multiple Sclerosis Center

(RMMSC), a private, nonprofit research and compre-hensive care facility at Swedish Medical Center in Den-ver, is recruiting for a Ph.D. scientist to conduct researchinto the molecular immunology of MS. Competitivesalary and benefit package. Submit curriculum vitae to:Ron Murray, M.D., RMMSC, Box 2901, 501 EastHampden Avenue, Englewood, CO 80110.

MOLECULAR RETROVIROLOGIST RE-SEARCH ASSOCIATE position is available immedi-ately in the Department of Infectious Diseases andMicrobiology, at the Graduate School of Public Health,to study the genetic variation, gene regulation andlatency of HIV. Candidates must have experience inretrovirs pathogenesis and molecular biology and becapable of independent research. Salary commensuratewith expenence. Send curriculum vitae and three namesof references to: Dr. Phalguni Gupta, 426 Parran Hall,Graduate School of Public HXealth, University ofPittsburgh, Pittsburgh, PA 15261. The University ofPittsburgh is an Afirmative Action/Equal OpportunityEmployer.

ORTHOPEDICBIOMECHANICAL ENGINEERWEST VIRGINIA UNIVERSITY

SCHOOL OF MEDICINEWest Virginia University School ofMedicine invites

plications from biomechanicians for a tenured-track facultyposition with joint appointments in the Departments ofOrthopedic Surgery and Mechanical Engineering.

Candidates must hold a Ph.D. in mechanical engineer-ing and have a background in mechanical testing, model-ing, and motion analysis. Position involves research andteaching.

Salary and rank will be commensurate with experience.Send applications with rcsum's by 31 December 1988 to:

Eric L. Radin, M.D.Professor and Chairman

De.partment of Orthopedic SurgeryWest Vsrginia University gSchool of Mledicine

3606 HSN, Health Sciences CenterMorgantown, WV 26506

West Virginia University is an Equal EmploymentOpportunity/Affirmative Action Employer

i8 NOVEMBER 1988

Diagnostic Products Corporation

Diagnostic Products Corporation, a leading independent and well-established biotechnology company in Southern California, is seek-ing qualified and experienced individuals for the following scientificpositions. Salary and benefits are competitive and will be commen-surate with experience.

SCIENTISTS, MOLECULAR BIOLOGYCareer-oriented candidates with a PHD degree and at least 3 yearspost-doctoral training in molecular biology and immunology areencouraged to apply to this team of scientists that will form the nucleusof the molecular biology department scientific staff. Candidates shouldhave experience with nucleic acid biochemistry, recombinant DNAtechnology and DNA sequencing as well as tissue culture. Thischallenging appointment requires good communication skills and ag-gressive scientific talents. Reference: R-1

SCIENTISTS, PROTEIN BIOCHEMISTRYCandidates with a PHD with a post-doctoral training in proteinbiochemistry are encouraged to apply to this team of scientists thatwill participate in the isolation and physical characterization of a varie-ty of proteins and/or peptides. A thorough background in peptide syn-thesis, classical and solid-phase, is essential. Knowledge of carbo-hydrate and nucleic acid biochemistry is preferred. Also, candidatesshould have experience with HPLC, FPLC, affinity chromatographyand other methods of protein purification. Reference: R-2

TECHNICAL PRODUCT MANAGERCandidate will supervise all technical aspects of several in vitrodiagnostic product lines, including introduction of new products, pro-cess and product improvements, technical training of distributors andtechnical interactions of customers. This challenging position will givepersonal growth within and beyond the laboratory.Candidates with a PHD and up to 2 years of experience or a Mastersdegree and 4-5 years of experience in Biochemistry, Immunology,or related disciplines should apply. Previous experience with in vitrodiagnostics is a definite plus. Reference: T-1

Please send your resume and salary requirements,plus reference to position of interest to:

Diagnostic Products Corporation5700 West 96th StreetLos Angeles, CA 90045

Attention: Personnel

ONCOLOGY RESEARCHWASHINGTON DC AREA

Molecular Oncology, Inc. is a young, fast-growingbiotech research company involved in the transfer ofthe latest molecular diagnostics to the clinical laboratoryIf you're an enthusiastic individual with the demonstratedability to apply advanced management and research skillsto cancer diagnosis, we have a place for you on our team.

LABORATORY DIRECTOR-MOLECULAR BIOLOGYDuties include the daily supervision of a staff of inves-

tigators examining the correlation of DNA arrangementand protein expression with tumor identification andprogression. M.D., Ph.D, or M.S. degree with 2 to 5 yearssupervisory experience required.

LABORATORY DIRECTOR-CYTOMETRYResponsible for the daily supervision of a staff of inves-

tigators applying the latest techniques in flow cytometryand image analysis to problems of protein expression andDNA analysis related to tumor diagnosis and progression.M.D., Ph.D, or M.S. degree with 2 to 5 years supervisoryexperience required.Send employment Molecular Oncology, Inc.history and c.v. to: j3a1^ Personnel Manager14AW 19 Firstfield RoadMOI is an equal Gaithersburg, MD 20878opportunity emplovtr.

STATE UNIVERSITY OF NEW YORK AT BUFFALOBIOLOGICAL SCIENCES-FACULTY OPENINGSTWO ASSISTANT PROFESSORSHIPS: We anticipate that we will behiring two faculty for Fall 1989. Those appointed will be individualswhose research program is in the forefront of their field and who willbe able to interact with other members of our faculty.One position in ECOLOGY/EVOLUTIONARY BIOLOGY is open tocandidates with all specialities, however we are particularly interest-ed in the area of aquatic and plant population ecology.The second position will be open to candidates who will be expectedto be utilizing modern genetic and molecular approaches to the studyof one of the following areas: (a) the immune system at the cellularlevel, (b) the development of an organism which provides a modelsystem for studies in development, or (c) regulation in an organismto provide a model for studies of regulation at the level of genetranscription.Successful candidates will be expected to have completed at leasttwo to three years of post-doctoral experience, demonstrate experi-ence in a productive research program, be able to describe in detailplans for future research activities, and show promise for establish-ing a fundable independent research program.

Candidates will also be expected to demonstrate above averageteaching ability for both undergraduate and graduate teaching.Salary will be nationally competitive; excellent laboratory space andequipment available.To apply, candidates must submit a curriculum vitae, including astatement of research background and teaching experience, and atleast three letters of reference, to Dr. Darrell Doyle, Chairman,Department of Biological Sciences, 109 Cooke Hall, State Univer-sity of New York at Buffalo, Buffalo, NY, 14260. Applications will bereceived until January 13, 1989, or until the position is filledthereafter.

State University of New York is an Affirmative Action/Equal Opportunity Employer.

RESEARCH FELLOWA$30,1 OO-A$43,861DIVISION OF PLANT INDUSTRYCANBERRA AUSTRALIAGENERAL: The CSIRO Division of Plant Industry undertakes research inplant sciences and rural industries directed towards improving theprofitability of agriculture and the management and utilisation of theAustralian flora and vegetation. Its plant improvement investigations rangefrom basic molecular biology to applied plant breeding. Over the past 30years the breeding program on the drought, hardy pasture grass, Phalarisacquatica, provided all of Australia's new cultivars.THE JOB: The appointee will conduct grazing experiments to analyse theeffects of seed retention, asynchronous tiller elongation, vernalisationarequirement and other factors on the nutritive value and persistence of P.acquatica cultivars and breeding lines. The appointee will also studyquantitive genetics of key factors to design optional breeding strategies.THE PERSON: Applicants should have a Ph.D or equivalent qualificationsin a relevant field. A sound knowledge of breeding of herbaceous perennialor annual plants, preferably open-pollinated pasture plants, is required.CONDITIONS: Appointment will be for a term of 3 years with AustralianGovernment Superannuation benefits available.MORE INFORMATION: Prospective applicants are invited to telephone DrR.N. Oram 61 62 46 5082 for further information. A copy of the detailed dutystatement and selection criteria may be obtained by telephoning61 62 46 5357.APPLICATIONS: Applications should be submitted by 4 weeks afterpublication, 1988 and quote reference number N9109. They should beframed against the selection criteria, and state relevantpersonal particulars including details ofqualifications and experience. Applicants shouldnominate at least two professional referees andaddress their applications to:

The Chief EiCSIRO Division of Plant IndustryGPO Box 1600Canberra, ACT 2601AUSTRALIA C S I RO

AUSTRALIA

CSIRO IS AN EQUAL OPPORTUNITY EMPLOYER <

Pathology

Section ChiefDiagnostic Molecular PathologySaint Barnabas Medical Center is a 705-bed regional acutecare hospital located in suburban NJ. The Department ofPathology performs a diversity of diagnostic tests and isamong one of the most sophisticated of its kind in thehealthcare field to-date. We currently have a positionavailable for a Section Chief of Diagnostic MolecularPathology to work in this highly specialized and advanceddepartment.As the Section Chief, under the direction of the Chief ofThe Diagnostic Molecular Pathology Service, yourresponsibilities include: establishing recombinant DNAtechnology, supervising and assisting laboratory person-nel in your section, as well as working with other sectionsin the Department of Pathology. Other duties include: lec-turing to students, technologists, and house staff, as wellas participating in educational and research projects.Applicants should be capable of working independentlyand must have a Doctoral Degree in Molecular Biology,preferably with 3-5 years experience.We offer a highly competitive salary and a unique array ofbenefits inc[uding: an employer funded tax-shelteredannuity program, complete medical coverage, and a newKindercare Learning Center! Please submit resume withsalary requirement to Dr. J. Manning, (201) 533-5705,Department of Pathology, Saint Barnabas Medical Cen-ter, Old Short Hills Road, Livingston, NJ 07039. We are anequal opportunity employer M7F/H/V

* * SAINT BARNABAS* * MEDICAL CENTER

"Real Challenges, Real Rewards"

Old Short Hills Road, Livingston, New Jersey 0)7039

r

6 J,

R & D/Product SupportAmersham Corporation, a respected leader in the diagnostic industry, is expanding its Diagnostic Systems Division at arapid pace and is seeking a broad range of scientific talent to assume key roles in that expansion. Exciting growth willbe occurring in research and development, marketing, product support, and field service over the next several months.Opportunities in product development have created an immediate need for the following individuals possessing Ph.D.degrees in Biochemistry, Immunology or other appropriate fields.

RESEARCH SCIENTISTApplicants should have a minimum of 5 years industrial experience in the area of immunodiagnostics. Individuals withproduct development and launch experience on instrumentation-based thyroid, cancer, hormone, or infectious diseaseproducts are being sought. Preference will be given to individuals who have worked closely with parallel instrumentationdevelopment. Supervisory experience and interpersonal skills required for a team approach are essential.

PRODUCT SUPPORT SCIENTISTThe ideal candidate will possess 3 to 5 years experience in product support or development of diagnostiic productsspecifically thyroid immunoassay products. Individuals with extensive experience in method development, experimentaldesign and product problem solving are sought. Managerial skills would be an asset in the supervision of a product supportgroup.Amersham Corporation is located in a pleasant suburban area 25 miles northwest of downtown Chicago. We are offeringexcellent starting salary, an attractive benefits package, and the opportunity to make a significant contribution to ourDiagnostic Systems team. To apply for our immediate openings, or apply for future opportunities in marketing, productsupport, and field service, please submit your resume in confidence to:

Human Resources ManagerAMERSHAM CORPORATION

2636 S. Clearbrook DriveArlington Heights, IL 60005-4692

Equal Opportunity Employer, M/F/V/H

AImershaml

International Institute of Tropical AgricultureIbadan, Nigeria

LEADER, RESOURCE MANAGEMENT UNITIITA invites applications for the senior research position of Leader, Resource Management Unit.IITA is an international agricultural research institute in a world-wide consortium of 13 centers organized by the World Bank, Food and Agriculture Organization and

United Nations Development Program. The Institute has outreach programs in many countries of sub-Saharan Africa. IITA scientists from 45 nations work in partnershipwith national agricultural agencies to increase food production in tropical Africa, and ultimately to raise the productivity and income of family farmers.

The goal of resource management research at IITA is to develop economically viable farming systems which permit increased and sustainable production by familyfarmers. Good management practices should enable them to make more effective use of their resources: soil, radiation, vegetation, water, material inputs, labor andother energy sources. The development of farming systems to support the population of Africa in the 21 st century is one of the most profound challenges to internationalagriculture. For this reason, IITA plans to increase the strength of its research effort in this field over the coming years.

The Leader of the Resource Management Unit will direct a multidisciplinary team of soil scientists, agronomists, ecologists, weed scientists, an agroclimatologist, aneconomist and agricultural engineers in (a) studying the physical, chemical, biological and socio-economic elements of the natural resource base; (b) analyzing thedeterminants of stability, productivity and degradation; and (c) designing improved resource management systems and in adapting them to the farming systems of themajor ecosystems of West and Central Africa.

Candidates should possess a relevant research background (PhD or equivalent degree in an appropriate subject), and have had a minimum of five years ofinternational experience. They should be keen scientists with a vision of how applied research can address practical problems. They must be capable of organizing theirteam in a coherent program to make their vision a reality.

The salary and benefits are competitive, and include housing, use of a personal car, children's educational allowances, annual home leave travel, health services andother benefits. The Institute's headquarters, research facilities, and residential and recreational areas are situated on an attractive 1,000-hectare campus outside ofIbadan.

Applicants for the position of Leader, Resource Mangement Unit, are invited to send their curriculum vitae, date of availability, and names and addresses of threereferees to Dr. Laurence D. Stifel, Director General, c/o L.W. Lambourn & Co. Ltd., Carolyn House, 26 Dingwall Road, Croydon CR9 3EE, England.

IITA currently also has the following positions open: agricultural economist, plant breeder, Striga biologist, soil chemist, training materials specialist and seniorscience writer/editor. The full announcements of any of those positions will be sent on request.

August 1988

a ik

POSITIONS OPEN

SEARCH EXTENDEDMOLECULAR STRUCTURAL BIOLOGYThe Department of Cell Biology and Neuroanatomy,

in cooperation with the newly established Center forStructural Biology at the University of Minnesota, isextending its search for a structural biologist with exper-tise in electron microscopy ofmacromolecules (includingproteins, glycoproteins, membranes and chromatin) andin computer image analysis. Areas of research interest ofthe successful applicant must complement ongoing pro-grams in the department in the areas of cytoskeleton,membrane proteins or extracellular proteins that interactwith cells. The appointment may range from ASSIST-ANT PROFESSOR (TENURE-TRACK) TO PRO-FESSOR (TENURED) depending upon qualifications(guidelnes for appointment at each level will be sent onrequest). Applicants must have a relevant graduate de-gree [either Ph.D. or M.D. (or both), or equivalentforeign degree] with at least 2 years of productivepostdoctoral experience. Teaching will be m coursestaught to medical and dental students by the department.In addition, training ofgraduate students and teaching inappropriate graduate programs will be required.

Applications (which should include a letter of intent,curriculum vitae, three letters of recommendation, and abrief statement of research goals) or nominations mustbe received no later than 1 February 1989, and should besent to Search Committee, Departnent of Cell Biolo-gy and Neuroanatomy, 4-135 Jackson Hall, 321Church Street, S.E., Minneapolis, MN 55455.

The University of Minnesota is an Equal OpportunityEducator and employer and specifically invites and encouragesapplicationsfrom women and minorities.

Tenure-track faculty position for NEUROSCIEN-TIST. Research focus in CNS neural plasticity and atleast 2 years of postdoctoral training preferred. Assistantprofessor rank, but higher level appointment may beconsidered. Send curriculum vitae with three letters ofrecommendation, statement of research goals, and nomore than three reprints to: L. C. Skeen, Chair, Biopsy-chology Search Committee, Department ofPsycholo-gy, University of Delaware, Newark, DE 19716, by31 January 1989. Women and members ofminority groups areespecially encouraged to apply. Equal Opportunity/AfirmativeAction Employer.

PHARMACOLOGISTThe Department of Pharmacology at the University of

North Dakota School of Medicine has a tenure-trackvacancy to be filled by July 1989 at the associate profes-sor level. Applicants must have a Ph.D. and teachingexperience with preference given to those with demon-strated research productivity in autonomic, cardiovascu-lar, chemotherapy, endocrine, or renal pharmacology anda demonstrated ability to gain extramural research fund-ing. Excellent laboratory space is available to support theresearch effort in a developing department. Candidatesshould submit curriculum vitae, a summary of researchplans, and names of three referees by 15 January 1989:Dr. John W. Vennes, Acting Chair, Department of

Pharmacology, School of Medicine, University ofNorth Dakota, Grand Forks, ND 58202. An EqualOpportunity Employer.

PHARMACOLOGYThe Department of Pharmacology, Division of Func-

tional Biology, of the West Virginia School of Osteo-pathic Medicine (WVSOM), seeks an ASSISTANT ORASSOCIATE PROFESSOR of pharmacology. Appli-cants must have a background in general physiology andpharmacology, with experience in cardiovascular andrenal pharmacology Significant teaching experience anda demonstrated ability to conduct independent researchare also required.Rank and salary will be commensurate with qualifica-

tions. Send current curriculum vitae and three letters ofrecommendation to: Chairperson, PharmacologySearch Committee, c/o Personnel Officc, WVSOM,400 North Lee Street, Lewisburg, WV 24901. Theposition is available immediately.WVSOM is an Afirmative Action/Equal Opportunity

Employer.

PHARMACOLOGISTWe seek to appoint a research assistant professor with

interest and experience in parasitic disease(s). Preferencewill be given to those with expertise in geohelminths,schistosomiasis and possibly filarisis. AvailabIe 1 July1989. Applications should include current curriculumvitae and the names of three references. Applicationdeadline: 1 January 1989. These should be sent to: Ms.Carol Taylor, Department of Biomedical Sciences,University of Illinois College of Medicine at Rock-ford, 1601 Parkview Avenue, Rockford, IL 61107.Equal Opportunity/Affirmative Action Employer.

PHYSIOLOGY FACULTY POSITION-The De-partment of Physiology, Chicago College of OsteopathicMedicine, invites applications for a tenure-track positionat the rank of ASSISTANT/ASSOCIATE PROFES-SOR. The successful candidate will develop a vigorous,fundable research program, preferably in an area thatcomplements existing programs in cardiovascular, diabe-tes and vascular smooth muscle research. Highly quali-fied candidates with research interests in other areas willalso be given serious consideration. Two years of post-doctoral experience, and the ability to teach humanphysiology to medical students are required. Candidatesshould send their curriculum vitae, reprints of selectedarticles, a statement of current research interests, and thenames of three references to: Stephen J. Kopp, Ph.D.,Chairman, Department of Physiology, Chicago Col-lege of Osteopathic Medicine, 555 31st Street,Downers Grove, IL 60515. Affirmative Action/EqualOpportunity Employer.

PLANT CELLULAR/MOLECULAR BIOLO-GIST. Applications are invited for a tenure-track posi-tion in molecular or cellular biology with experience inplant systems. Initial responsibilities include participa-tion in a core course for majors on genetics and develop-ment, developing a general education course m scienceand technology, and additional courses in area of special-ization. Ph.D. strongly preferred. Send letter of applica-tion outlining research and teaching interests, curnculumvitae, and letters from three references before 15 Decem-ber 1988 to: Dr. Jack Harclerode, Department ofBiology, Bucknell University, Lewisburg, PA 17837.Telephone: 717-524-1961. Applications from women andmembers of minority groups are encouraged.

PLANT ECOLOGY ANDPLANT PHYSIOLOGYMIAMI UNIVERSITY

The Miami University Department of Botany invitesapplications for two tenure-track positions at the assist-ant. professor level to begin 23 August 1989. Oneposition is for a PHYSIOLOGIST emphasizing plantmetabolism. The second position is for a POPULA-TION or EVOLUTIONARY ECOLOGIST. Re-sponsibilities include teaching undergraduate and gradu-ate courses, research and the direction of master's anddoctoral students. A Ph.D. in an appropriate discipline isrequired. Preference will be given to candidates withpostdoctoral experience and demonstrated success inboth teaching and independent research. Curriculumvitae, a one-page statement of teaching goals, a one-pagestatement of research objectives, and three letters ofrecommendation should be received by 6 January 1989.Address materials to: Dr. Jerry W. McClure (Physiolo-gy) or Dr. John L. Vankat (Ecology), Department ofBotany, Miami University, Oxford, OH 45056. Affir-mative Action/Equal Opportunity Employer.

POSTDOCTORAL FELLOWA 2-year appointment of postdoctoral fellowship in

speech science iS available at The Ohio State University,Division of Speech and Hearing Science. Strong researchbackgrounds in phonological theory and/or Al-orientedcomputational methods are desirable. Large amounts ofarticulatory data from the University of Wisconsin mi-crobeam facility are available as well as an advancedcomputational environment including several SUN-4workstations. Candidates from any discipline are invitedto contact: Professors Larry Feth and Osamu Fuji-mura, Division of Speech and Hearing, The OhioState University, 154 North Oval Mall, Columbus,OH 43210. Applications should include curriculumvitae as well as names, addresses, and telephone numbersfor at least two recommendations, and must arrive by 9December 1988. OSU is an Afirmative Action/Equal Op-portunity Employer.

PLANT GROWTH AND DEVELOPMENTThe Division of Sciences at Washington State Univer-

sity is accepting applications for a tenure-track facultyposition m plant biology at the level of ASSISTANTPROFESSOR. The position requires participation inteaching core curriculum courses in the areas of plantdevelopment and stnrctural botany, and appropriateteaching experience is desirable. The successt candatewill be expected to develop a strong externally fundedresearch program concerned with the reulation of plantdevelopment at the molecular, biochemical and/or phys-iological level. Preference will be given to candidatesemploying contemporary methods to study the regula-tion of organ or whole plant development. A Ph.D. withacademic training in a pertinent area of plant biology isrequired, and postdoctoral experience is preferred. Appli-cants should submit curricu[um vitae, statement of re-search and teaching interests, selected reprints, andnames offour references to: Dr. Vincent R. Franceschi,Chair, Search Committee, Department of Botany,Washington State University, Pullman, WA 99164-4230. Application deadline is 9 January 1989. WSU is anEqual Opportunity/Affirmative Action Educator and Employer.Proteaed group members are encouraged to apply.

PLANT SYSTEMATICSHARVARD UNIVERSITY

DEPARTMENT OF ORGANISMIC ANDEVOLUTIONARY BIOLOGY

TWO POSMONSFULL PROFESSOR-evolution and phylogeny of

vascular plants, and non-tenured professor at the AS-SISTANT OR ASSOCIATE rank-systematics ofplants or fungi. Candidates should employ moleculartechniques in their research.

Applicants should have demonstrated excellence inresearch and a strong commitment to teaching at thegraduate and undergraduate levels. Curriculum vitae,statement of interest and names of three recommenda-tions should be sent to the committee no later than 1January 1989. Committee: Plant Systematics Search,Department of Orgmnismic and Evolutionary Biolo-gy, 26 Oxford Street, Cambridge, MA 02138.

Harvard University is an Affirmative Aaion/Equal Oppor-tunity Employer.

POSTDOCTORALASSOCIATE IN PLANT/IN-SECT RELATIONS: Available immediately with 2-year appointment to study effects of biological nitrogenfixation in legumes on herbivorous insects. Requiresstrong interest and background in physiological respons-es of plants to environment and insect behavior/nutri-tional ecology. Applications, including curriculum vitae,a summary of research interests and experience, andnames of three references should be forwarded to: Dr.Patrick R. Hughes, Boyce Thompson Institute forPlant Research, Cornell University, Ithaca, NY14853.

POSTDOCTORAL FELLOW: A biochemist withstrong background in analytical food chemistry and/ortoxicology is required to work on a National ResearchCouncilfunded research project focused on "domoicacid" shellfish toxin. Previous experience in related fieldis desirable. Two-year appointment. Applications shouldinclude curriculum vitae, names and address of threereferences, and pertinent publications. Submit to: Dr.M. S. Nijjar, Department ofAnatomy and Physiolo-gy, University of Prince Edward Island, Charlotte-town, P.E.I., Canada, ClA 4P3.

POSTDOCTORAL FELLOWSHIPPSYCHONEUROIMMUNOLOGY

The Departments of Microbiology and Psychiatry ofBoston University School of Medicine are offering a

postdoctoral fellowship in the field of psychoneuroim-munology. The position is available 1 January 1989.Training will involve laboratory research on the effect(s)of stress on the immune system of small rodents and willinclude aspects of neuroendocrinology, psychiatry/psy-chology and statistics. Please apply in writing, andprovide curriculum vitae and the names of three refer-ences. Please reply by 1 December 1988 to: Paul H.Black, M.D., Department of Microbiology, BostonUniversity School of Medicine, Boston, MA 02118.

Equal Opportunity/Affirmative Action Employer.

SCIENCE, VOL. 242io88

POSITIONS OPEN POSITIONS OPEN

"If ReearchIs What You Do Best...

Consider the Variety of Possibilitiesat Genetics Institute."

As the innovative leader in today's dynamic industry...biotechnolo$y, Genetics Institute can offer you aresearch environment that's rich in creativity and entrepreneurial spirit. Whether your background stemsfrom academia or another research setting, we at Genetics Institute encourage our research professionalsto explore their talents in a stimulating, scientific atmosphere. It is this type of environment that hasenabled our research team to make the kind ofcontributions deserving ofour reputation in the applicationand creation of recombinant DNA technology.

Mammalian Cell Expression/Protein AnalysisWe are s n al individuals at the BA, MA and/or Ph.D.Iev, with epresion and protin aulysto in a group studying combinant immunoglobulins intendedfor therapeutic purposes. The ideal candidate has experiencein propagation of transformed tell lines, DNA transfections and/orprotein harac tion. A back in i Imunology or rDNAexperience is also beneficial, but not a p iimte for the position.

ImmunologyWe are currentdy acepting applications from qualified individualsin the area of Applied Immunochemistry. Ideal candidates willhave MS or PhD in Immunology or Biochemistry, and 2-4years' relevant experience in the purification, characterization,and utilization of monoclonal and polyclonal antibodies.Familiarity with isotopic and enzymatic immunoassay proce-dures, including chemical modifications to antibodies and/orantigens are essential for the successful candidate. A backgroundin molecular biology, although desirable, is not required.

Analytical BiochemistryWe have an immediate opening for an analytical biochemist inour Carbohydrate Chemistry group. Primary responsibilitieswill include analyis ofthe oligosaccharides from glycoprotcinsby gas and liquid chromatography, maintenance ofchromato-graphic instrumentation, and intcrpretation of data. The idealcandidate should possess a BS in Chemistry/Biology with oneyear of laboratory experience and have cxcellent written andverbal communications skills. Previous experience with GC orLC desirable, though not necessary.

Assay DevelopmentWe are expanding our research activities to include a dedicatedassay development group to be responsible for performing anddeveloping assays to support our research and clirical developmcntorganization in the areas of hematopoietic and other growthfactors, fibrinolysis'and hemostatsis. We arc secking several assayspecialists in the following areas to be a part of this start-up group:

Immunoassays Enzymatic assaysBioassays

A Bachelor's or Master's degree as well as experiencc in run-ning validated assays for clinical or in vitro diagnostics is desired.In addition, we are seeking a Ph.D. with significant expericncein immunoassay development and implementation for proteintherapeutics. Thlis individual would be expected to take a leadrole in developing immunoassays, providing supervision forthe other assay areas within the group, and interacting withscientists and physicians in research and clinical development.

Molecular BiologyDNA SequencingAn opportunity exists for a Bachelor's or Master's level candi-date with 1-2 years of experience in molecular biology. Thisindividual will be responsible for DNA sequencing by molecularbiology techniques.

Tissue Growth & RepairA position is available in our Tissue Growth and Repair labora-tory conducting bone rowth factor research. This position re-quircs a Bachelor's or Master's and 2-3 years of experience inmolecular biology techniques including cDNA library screen-ing, clone characterization and RNA techniques.

Microbial ExpressionWe are currcntly seeking a Bachelor's or Master's level scien-tist to join our Microbiology group. This individual will beinvolved in expression and analysis of heterologous geneproducts in microbial systems, principally in E. coli. A back-ground in microbiology is preferred, and familiarity with rDNAtechniques is desirable.

Protein EngineeringWe seck a highly motivated scientist to contributc to the syn-thcsis of novel recombinant protein. The ideal candidate willbe actively involved in DNA mutagenesis, vector construc-tion/design, and enzymatic assays. lAwis opportunity requiresa BS degree in Biology or related life science with a minimumof one year's cxpericnce in molecular biology.

ManunalianCell CultureAn opportunity exists within the Biochemical Engineeringgroup of our Mammalian Cell Culturc laboratory for an in-dividual with a Bachelor's or Master's dcgrec in a biologicalscience or an enginecring discipline. Experiencc in ccll cultureas well as analytical tcchniqucs such as gel clectrophoresis,Wcstcrn blot analysis, autoradiography, wet chemistry and en-zymatic assays is required. Expericnce in the operation ofbiorcactors would be an advantagc but is not essential.

We offer a stimulating scientific environment in additionto an excellent salary and a complete benefits package.Qualified applicants should forward their resumes, in con-fidence, to Sheri Rist, Genetics Institute, 87 Cambridge-Park Drive, Cambridge, MA 02140.

An Equal Opportqnity/Aflirmative Action Employer

Genetics Institute

M M I

M- -1

POSITIONS OPEN

POSTDOCITORAL FELLOW: Molecular biologistto study prolactin-stimulated genetic transcription inmphocytes. Expertise in cell culture, RIA or EIA,

Western and Northern blots. Opportunity to uncovernew insight into cell function related to proliferativediseases. Salary commensurate with NIH guidelines.Closing date will be 30 December 1988. Resume to:Diane H. Russell, Ph.D., Professor and Head, De-partment ofPharmacology and Therapeutics, Univer-sity of South Florida, College of Medicine, MDC-9,Tampa, FL 33612. An Equal Opportunity/AffirmativeAction Employer.

POSTDOCTORAL FELLOWSHIP POSMONS(two) available immediately to study cellular and molecu-lar biology of atherosckrosis and lipid metabolism. Re-search projects include: regulation of apolipoproteingene expression; cellular assembly and secretion ofipoproteins; modeling ofintravascular lipoprotein trans-formations; and molecular genetics ofhuman lipoproteindisorders. Background in cell biology and/or biochemis-try desirable. Must be citizen or permanent resident. Sendr6sumi and namnes and addresses of three references to:Trudy M. Forte, Ph.D., Lawrence Berkeley Labora-tory, University of California, #1 Cyclotron Road,Berkcley, CA 94720. An Equal Opportunity Employer,M/F/H.

POSTDOCTORAL FELLOWSHIP/RESEARCHASSOCIATE in studying protein folding and dynamicsusing site-directed labeling and time-resolved fluores-cence spectroscopy. A 2-year position with optionalextension is available immediately. Expenrence m fluores-cence spectroscopy and protein chemistry is an advan-tage. This project is a collaboration of Bar-Ilan Universi-ty and the Weizmann Institute. Send curriculum vitaeand names of three referees to: Dr. Elisha Haas, Chemi-cal Physics Department, Weizmann Institute of Sci-ence, Rehovot 76100, Israe. Bitnet: CFHAAS atWEIZMANN.

POSTDOCTORAL POSMIION available immedi-ately to study myelin antiaens and characterize immuneresponses to them in multiple sclerosis. A background inimmunology or molecular biology required. Send curric-ulum vitae and three references to: Jreq I. Greenstein,M.D., Department of Neurology, Temple UnivcrsitySchool ofMedicinc, 3401 Norti Broad Street, Phila-delphia, PA 19140. An Equal Opportunity/AffirmativeAction Employer.

POSTDOCTORAL POSITIONA postdoctoral position is expected available summer-

fall 1989 for an outstanding individual with a strongbackground in cellular immunology. The individual se-lected will join a group investigating the regulationspecificity of the immunc rcsponsc to vesicular stomatitisvirus in mice at the clonal and molecular level. Appoint-ment will be held in the Department of Pathology atHarvard Medical School. Send curriculum vitae, state-ment of research interests, and names and addresses ofthree references by 1 March 1989 to: Dr. Carol Reiss,Division of Pediatric Oncology, Dana-Farber CancerInstitute, 44 Binney Street, Boston, MA 02115. AnAffirmative Action/Equal Opportunity Employer.

COASTAL TOXICOLOGY PROGRAMPOSTDOCTORAL POSMON available to char-

acterizc the petroleum hydrocarbons present in seawater,surficial sedinents, and fauna, and their environmentalfates. The position begins 1 January 1989 through 31October 1989, with strong possibility of extension con-tingent upon renewal offunding. Applicants should havea Ph.D. in either analytical, organic, or hysical chemis-try and experience with basic GC-MS and analyticalmethodology. Familiarity with sector and high-resolu-tionMS desirable. Send curriculum vitae and three lettersof recommendation to: Postdoctoral Search Commit-tee, Institute of Marine Sciences, 272 Applied Sci-ences Building, University of California, Santa Cruz,CA 95064. P[ease refer to job # T88-11. Closing datehas been extended to 15 December 1988. UCSC is anEqual Employment Opportunity/Affirmative Action/IRCAEmployer.

POSITIONS OPEN

POSITDOCTORAL POSMIION. Postdoctoral po-sition available to investgate the biosynthesis of second-ary metabolites in Streptomyces. Applicant should haveexperence in microbiology and in prokaryotic molecularbiology. Research to involve preparation of blockedmutants, cosynthesis experiments with mutants, anddoning of antibiotic biosynthesis genes. Send resumeand three letters of reference to: R. J. Parry, Depart-ment of Chemistry, Rice University, P.O. Box 1892,Houston, TX 77251. An Equal Opportunity/AfirmativeAcion Employer.

POSTDOCTORAL POSMON available 15 No-vember 1988 for studies on the pathogenesis of abacterial disease in salmon and the development ofimmunodiagnostics. Salary range: $21,000 to $24,000.Submit curriculum vitae and three letters of reference by2 December 1988 to: Dr. S. Kaattari, Department ofMicrobiology, Oregon State University, Corvallis,OR97331-3804. Oregon State University is an AffirmativeAction/Equal Opportunity Employer and complies with section504 ofthe Rehabilitation Act of 1973 and has a policy of beingresponsive to the needs of dual-career couples.

POSTDOCI)ORAL POSMON available to studycalcium channels of presynaptic terminals and the role ofG-proteins and phosphorylation in the regulation ofCa2+-dependent neurotransmitter release. This study ispart of a multidisciplinary investigation into the molecu-lar mechanisms and regulation of synaptic transmissionusing a combination of approaches including molecularbiology, protein purification, patch-clamp, caged mole-cules and Fura-2 in a preparation of giant synapticterminals. Send curriculum vitae and names and address-es of three references to: Dr. P. G. Haydon, Depart-mcnt of Zoology, Iowa State University, Ames, IA50011.

POSTDOCTORAL POSMON INMARINE SCIENCE

Skidaway Institute of Oceanography invites applica-tions for a 2-year, postdoctoral position in marine sci-ence. The position is open to scicntists interested inparcipatig in interdisciplinary oceanographic research.Special consideration will be given those whose researchinterests indude marine sedimentary geology, sedimenttransport and boundary-layer processes, or interactionsof ocean circulation and biological processes. A letter ofapplication induding curriculum vitae, a statement ofcurrent and future research interests, and names andaddresses of thrce persons who can be contacted forletters of reference should be sent to: Dr. James Eck-man, Skidaway Institute of Oceanography, P.O. Box13687, Savannah, GA 31416. Telephone: 912-356-2467. The deadline for application is 31 January 1989.

Skidaway Institute ofOceanography is an Equal Opportuni-ty/Affirmative Action Employer.

POSTDOCTORAL POSMIION IN MOLECU-LAR BIOLOGY available immediately to study acloned DNA repair gene in both Drosophita and humans.Candidate must have experience with standard moleculartechniques and will be expected to take an active role indeveloping and carrying out research in the analysis ofthe cloned genes. Send curriculum vitae and three lettersof reference to: Dr. Mark R Kelley, Department ofBiochemistry, Loyola University of Chicago, StritchSchool of Medicine, 2160 South First Avenue, May-wood, IL 60153.

POSTDOCTORAL POSMON IN PALEOBI-OLOGY available 1 December 1988 to collaborate instudies on the origin and evolution of major vascularElant groups emphasizing morphometric and computer-based mocling techniques. Background in plant sciences

and experience with computers desirable. Salary approxi-mately $22,000 per year. Reply with curriculum vitae,statement of research goals/interests, and three letters ofreference to: Dr. William Stein, Center for Evolutionand Paleoenvironment, SUNY-Binghamton, Bing-hamton NY 13901. SUNY-Binghamton is an Equal Op-portunity/Affirmative Action Employer.

POSITIONS OPEN

POSTDOCTORAL POSMON. Available in Janu-ary 1988 to join group investigating the cell biology,biochemistry and molecular biology of growth factorreceptors, novel tumor promoters and related sigaltransduction pathways. Experience in protein analysisand/or recombinant DNA techniques highly desirable.Send curriculum vitae to: Dr. Marsha Rosner, Univer-sity of Chicago, Ben May Institute, 5841 SouthMaryland Avenue, Box 424, Chicago, IL 60637. TheUniversity of Chicago is an Equal Opportunity/AffinmativeAcion Employer.

POSTDOCTORAL POSMON in cellular toxicol-ogy available early 1989 to develop in vitro systems toevaluate the toxicity ofxenobiotics to the eye and skin. A3-year project will focus on the development of eye andskin cell cultures as experimental too[s to identify andpredict the toxicity of dermal and ocular toxicants. Astrong background in toxicology and biochemistry isrequired; knowledge of cell culture techniques is desir-able. Send vitae and the names of three references to:

Daniel AcostaCollege of Pharmacy

The University of TexasAustin, TX 78712

POSTDOCTORAL POSMON-January 1989.To study structure-function relationships of contractileproteins utilizing chemical, physical, and immunologicalmethods. Expenence in protein and peptide chemistrywould be desirable. Send curriculum vitae and names ofthree references to: Dr. Morris Burke, Department ofBiology, Casc Western Reserve University, Cleve-land,OH 44106. An Equal Opportunity/Afirmative ActionEmployer.

POSTDOCTORAL POSITION IN HORMONERECEPTOR MOLECULAR BIOLOGY ANDBIOCHEMISTRY. Parathyroid hormone receptor iso-lation, characterization, sequencing, and molecular biol-ogy. Immediate opening for beginning postdoctoralcandidates. Excellent salary and fringe benefts. Stimulat-ing intellectual environment in a basic science depart-ment. Call or apply directly to: J. E. Zull, Departmentof Biology, Case Western Reserve University, Cleve-land, OH 44106. Telephone: 216-368-3572. CWRUis an Equal Opportunity/Afirmative Action Employer.

POSTDOCTORAL POSITIONSImmediately available to study human humoral re-

sponse to HIV. Immunochemistry, molecular biology,or retrovirology background required. Candidate mustqualify for postdoctoral appointment in the DepartmentofMedicine at Brown Umversity. Send curriculum vitae,names of references to: Marshall Posner, M.D., Direc-tor, Human Monoclonal Antibody Laboratory, Rog-er Williams Cancer Center, 825 Chalkstone Avenue,Providence, RI 02908. An Equal Opportunity/AfirmativeAcion Employer.

POSTDOCTORAL POSMONSIN MOLECULAR BIOLOGY

Two positions are available immediately in an activelaboratory for Ph.D.'s in biochemistrv or microbiology.Research areas include plasmid DN6A re lication andregulation ofgene expression. Send curriculum vitae andnames of two references to: Dr. Saleem Khan, Depart-ment of Microbiology, University of PittsburghSchool of Medicinc, 720 Scaife Ha Pittsburgh, PA15261.

POSTDOCTORAL'RESEARCH ASSOCIATE.Position available immediately for recent Ph.D. interest-ed in electrophysiological and pharmacological studies ofaxon-Schwann cell interactions and nervous system ionichomeostasis. Experience in small cell electrophysiolo-gy, ion selective electrodes and/or patch clamp givenpreference. Salary up to $21,000, renewable. Sen cur-riculum vitae and three references to: Dr. Edward M.Lieberman, Department ofPhysiolo0 , East CarolinaUniversity School of Medicine, Greenville, NC27858-4354. ECU is an Afirmative Action/Equal Oppor-tunity Employer. Federal law requires proper documentation ofidentity and employability at the time of employment. It isrequested this documentation be induded in your application.

SCIENCE, VOL. 242lOgo

POSITIONS OPEN

POSTDOCTORAL POSMONS available 1 Janu-ary 1989 for studies of the expression of carbohydrateantigens in human cancers [JBC, 262, 11331 and 15649(1987)] involving glycosyltransferase purification andcharacterization, differentiation and mofecular biologicalaspects of expression. Applicants should have appropri-ate training m biochemistry, cell or molecular biology.Send letter describing training and future goals, curricu-lum vitae, and names of three references to: Dr. EricHolmes, Pacific Northwest Research Foundation,720 Broadway, Scattle, WA 98122.

POSTDOCTORAL POSITIONSThe Department of Physiology and Biophysics at the

University of Tennessee, Memphis, has openings at thepostdoctoral level in the areas of cardiovascular (micro-circulatory, role of autocoids in control of regionalvascular beds, and CNS mechanism), control offluid andelectrolyte-balance, CNS (temperature regulation, sleep,and the interaction of the immune system and the CNS),neuroendocrinology, neonatal cerebral circulation (eico-sanoids, activated oxygen, neurotransmitters, pathophys-iology), and renal-enrocne (renin angiotensim-aldoster-one axis) physiology. Individuals with Ph.D., M.D., orequivalent degrees should send curriculum vitae and thenames, addresses, and telephone numbers of three indi-viduals to give reference to: Dr. Edward G. Schneider,Associate Professor and Acting Chairman, Universityof Tennessee, Mcmphis, Department of Physiologyand Biophysics, 894 Union Avenue, Memphis, TN38163. The University of Tennessee, Memphis, is an EqualOpportunity Affirmative Action Employer. Minorities andwomen are encouraged to apply.

POSTDOCTORAL POSMIIONSIN IMMUNOLOGY

Recent expansion of the immunology program at St.Jude Children's Research Hospital has created new op-portunities for Postdoctoral Felows. The major interestsof individual faculty members include viral immunity (P.Doherty, J. Allan), lymphocyte ontogeny (J. Hurwitz,M. E. Conley), regulation of gene expression (C. Cole-clough), macrophage biology (W. Walker,M. Fishman)and B cell and idiotypic interactions (D. Metzger, A.Brown).

St. Jude Children's Research Hospital is a multidis-ciplinary biomedical research institution providing manyopportunities for collaborative interactions with, in par-ticular, strong programs in molecular virology, tumorbiology and growth factors. Annual salary begins at$22,000, commensurate with experience, and there is anexcellent benefits package.Send curriculum vitae and three letters of recommen-

dation to: Peter C. Doherty, Chairman, DepartmentofImmunology, St. Jude Children's Rescarch Hospi-tal, 332 North Lauderdale, Memphis, TN 38101.

POSTDOCTORAL RESEARCH ASSOCIATEto study the genetic effects of carcinogenic metal com-pounds. Background in biochemistry or molecular biolo-gy. Experience with tissue culture and recombinantD)A technology desirable. Laboratory located in ruralarea, 50 miles north ofNew York City. Salary negotiable.Send curriculum vitae and names and telephone numbersof three references to: Dr. Toby G. Rossman, Instituteof Environmental Medicine, New York UniversityMedical Center, 550 First Avenuc, Ncw York, NY10016. An Equal Opportunity Employer MIF.

NEW YORK UNIVERSITYMEDICAL SCHOOL

POSTDOCTORAL RESEARCHOPPORTUNITIES

Applications are invited for postdoctoral research be-ginning in winter/spring 1989 to study: (i) Mechanismsof signal transduction and induction of gene transcrip-tion through cell surface receptor activation ofmammali-an cells by cytokines; and (ii) Role of interferons andother cytokines in the regulation of cell gowth.

Experience in eukaryotic molecular biology and/orbiochemistry is desirable. Applicants must be elgible forfunding from the NIH (U.S. citizens and pemnanent resi-dents). tend letters of application, curriculum vitae, andnames and addresses ofthree references to: Dr. David E.Levy, Department of Pathology, NYU Medical Cen-ter, 550 First Avenue, New York, NY 10016.

Minorities are particularly encouraged to apply.

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POSTDOCTORAL POSITIONSIN MOLECULAR GENETICS

Applications are invited for several postdoc-toral positions in the Molecular GeneticsGroup of CIBA-GEIGY Ltd, Basle, for periodsof up to three years. We are a group of youngscientists working on the isolation of newgenes for proteins of pharmaceutical interest,the expression of foreign genes in mammaliancell cultures, molecular aspects of allergicreaction and the modulation of macrophagedifferentiation. Candidates should have a PhDwith 0-3 years postdoctoral experience, pref-erably with training/expertise in one or moreof the following areas: (1) DNA cloning meth-odologies, (2) Expression of recombinantgenes, (3) Mammalian tissue culture.

CIBA-GEIGY is a major pharmaceutical com-pany with an active interest and engagementin molecular biology. The Molecular Geneticssection is located in the company's main re-search facility situated in the heart of Basle,northwest Switzerland. Basle is a major cen-tre of excellence for both pure and appliedresearch in molecular biology in central Eu-rope, and it provides a stimulating academicand cultural environment.

Applications, including a curriculum vitae, asummary of relevant research backgroundand interests and the names of two refereesshould be sent under ref. "Science 950" toDr. W. Reber, CIBA-GEIGY Ltd, PersonnelDepartment, Postfach, CH-4002 Basle.

CIBA-GEIGY

i8 NOVEMBER I988

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FACULTY POSITIONSDEPARTMENT OF PHYSIOLOGY

NATIONAL UNIVERSITY OF SINGAPOREThe Department of Physiology of theNational University of Singapore invitesapplications for faculty positions fromindividuals with MD, PhD or equivalentdegrees and at least two years of post-doctoral experience in either of thefollowing areas: (a) aspects of cellularor molecular physiology related to theregulation of cell growth and differentia-tion and (b) mechanism of action ofhormones and hormone antagonists.The successful candidate will be ex-pected to develop an independent re-search programme in his or her area ofinterest and to teach human physiologyat undergraduate and postgraduatelevels. The level of appointment will becommensurate with qualifications andexperience. The applicants should sub-mit their curriculum vitae, a descriptionof research plans, and the names ofthree referees to the Director, PersonnelDepartment, National University of Singa-pore, 10 Kent Ridge Crescent, Singapore0511.

PHARMACEUTICALRESEARCH OPPORTUNITIESOCULON CORPORATION, a pioneer in the devel-opment of diagnostic and prophylactic modalSiesfor human cataract disease, has opportunitiesavailable in its Seattle research laboratories. Suc-cessful candidates will enjoy an exceptional envi-ronment in which to hone their professional skills,as well as the benefits of significant equity partici-pation in an early-stage venture.

PHARMACOLOGISTIndividual will be responsible for the design, initia-tion, and monitoring of preclinical and clinicalstudies to assess pharmacokinetics, bioavailabil-ity, and metabolism of new drug candidates. Re-quires Ph.D. or Pharm.D. degree with a minimumof 5 years postdoctoral experience in pharmacolo-gy, preferably in the ophthalmic area. Supervisoryand industry experience preferred.

ANALYTICAL CHEMISTResponsible for the development and applicationof advanced analytical methods to the character-ization of new drug candidates and their metabo-lites in support of preclinical and clinical studies.Requires Ph.D. in chemistry or biochemistry, witha minimum of three years postdoctoral experienceand familiarity with HPLC methods.

OCULON Corporation combines a competitivesalary and benefits package with a strong appreci-ation of the elements necessary to a successfuldrug discovery program. The Company's PacificNorthwest location provides easy access to recre-ational and cultural opportunities without state orlocal income taxes. To explore these positionsfurther, please send your CV in confidence to:

OCULON CORPORATION130 Nickerson StreetSeattle, WA 98109

EQUAL OPPORTUNITY EMPLOYER

POSTDOCTORAL FELLOWSHIPSat the University of Washington

COLLEGE OF OCEAN AND FISHERY SCIENCESApplications are requested from new or recent doctorates in science, engineer-ing and from individuals with equivalent degree stature in related fields forfellowships to be awarded in the College.The College consists of four units covering all aspects of marine science andmarine policy. Fellowship holders will be appointed in one of the followingdepartments:The School of Oceanography carries out basic research in physical oceanog-raphy, marine chemistry, marine geology, and geophysics and biologicaloceanography.The Institute for Marine Studies focuses multidisciplinary research on marinepolicy issues arising from man's use of the oceans; relevant disciplinary trainingmay be in any of the social or natural sciences or in law.The Applied Physics Laboratory carries out research in physical oceanography,polar science, underwater acoustics, and a wide range of engineering disci-plines.The School of Fisheries specializes in fish and shellfish systematics andecology, aquaculture, quantitative fishery management, environmental toxicolo-gy and food science.Fellowships are awarded for one year, renewable for a second year, with astipend of $25,000 and a modest research budget. Health insurance is alsoprovided. A complete application consists of transcripts of the applicant'sgraduate record, a vita, addresses and telephone numbers of three referees, asynopsis of the doctoral dissertation (not to exceed 2 pages) and month Ph.D.expected if not in hand, as well as a statement (not to exceed 2 pages) outliningthe research the applicant proposes to undertake at UW. Applicants should citetheir unit of primary interest and identify possible faculty mentor(s) in theCollege. Direct contact with such mentors is encouraged. All materials must bereceived by 1 January 1989. Awards will be announced in late March or earlyApril, 1989.Applications and any questions should be addressed to: Search Committee,COFS Postdoctoral Program, Office of the Dean HN-15, College of Ocean andFishery Sciences, University of Washington, Seattle, WA 98195.Equal Opportunity/Affirmative Action Institution

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CON5EKVATION | { NOSH ANNOUNCES RESIDENTC.E.O. 8X a POSTDOCTORAL

Wildlife Conservation International is the conserva- ASSOCIATESHIP AWARDStion program of the New York Zoological Society. FOR Ph.D & M.D. SCIENTISTSW.C.I., supporting a full time staff of field scientists The National Institute for Occupational Safety and Healthas well as short-term projects, strives to obtain a announces outstanding opportunities for research in:better understanding of the biology of endangered * BIOENGINEERING * PATHOLOGYspecies, the structure, function and stability of * BIOCHEMISTRY * PHYSIOLOGYlarge ecosystems, and applies this understanding | IMMUNOLOGY * PHARMACOLOGYto conservation. W.C.I. seeks a N.Y. City-based * MUTAGENESISDirector with the following credentials: The National Research Council in cooperation with the.Asignificant background in the conservation National Institute for Occupational, Safety and Health, Divi-. A significant background In the conservation sion of Respiratory Disease Studies in Morgantown, Westfield Virginia will offer competitive research awards in 1989 for

. A graduate degree, preferably PhD, in the bio- independent scientific research. Recipients will be free tological sciences work on problems of their own choice as guest investigators

* Budgeting & administrative experience at NIOSH. Duration of awards is one year renewable to a* Talent & experience with fundraising at the maximum of two. This program is open to experienced senior

corporate, foundatio & individual levelsscientists as well as to recent PhD and MD graduates. Sti-corporate, foundation & individual levels pends begin at $28,000 for recent graduates and are appro-* Experience in dealing with governmental agen- priately higher for seniors. Relocation reimbursement andcies, both foreign & domestic funds for professional travel on tenure are available, and a

Send resume to Ms. K. Rangel, Personnel Office health insurance program is offered.For further information and application materials please

NEWN YORK write to:ZOO LOG ICAL SOCIETY Associateship Programs (GR 430AINS)ZOVOLOCAICA SOCIETY NATIONALRSARCHCOUNCIL

185St-Southern Blvd., 2101 Constitution Avenue, N.W.185 St Southern Blvd., Washington, DC 20418Bronx, New York 10460 Deadline for application

equal opportunity employer m/f/h/v January 15.

rr LABORATORYANIMALVETERINARIAN /TOXICOLOGISTAmgen is a recognized leader in the development of human and animal health care products throughapplied biotechnology. As a result of our continued growth we have an immediate opportunity for alaboratory Animal Veterinarian/Toxicologist to participate and consult with Amgen scientists in thedevelopment of animal care programs related to exploratory research and toxicology studies.

Candidates for this position must have a DVM/VMD degree and be ACLAM board certified or eligiblefor certification. Essential requirements include a background and interest in clinical pathology andtoxicology as well as familiarity with current NIH and AAALAC guidelines for animal research.Research experience and the ability to conduct independent research are desirable.

Amgen offers an excellent compensation and benefits package as well as an attractive locationnorthwest of Los Angeles.

If you would like to be part of a company that places a high priority on its human resources and offers achallenging and rewarding environment, please send a complete CV, in confidence, to:

Recruitment, Dept. #355AMGEN1900 Oak Terrace LaneThousand OaksCA 91320 AkA,EEqual Opportunity EmployerLi

r Admik Adilk Mk n Admok..m " m . n Anik m m I BWM-c

POSITIONS OPEN

POSTDOCTORAL RESEARCH on thc effects ofincorporating nudeoside analogs into DNA. A positionis available in an ongoing research project for a candidatewith experience in enzlogy or nudeic acid research.Training will be provided in methods of studying en-zymes involved in DNA synthesis, induding the use oftransient state kinetics. Starting salary: $22,000 or high-er depending on relevant experience. To apply sendcurriculum vitae and three references to: Dr. R L.Blakkey, Department of Biochemical and ClinicalPharmacology, St. Jude Children's Research Hospi-tal, 332 Nosth Lauderdale, Memphis, TN 38101. AnEqual Opportunity Employer.

POSTDOCTORAL OR RESEARCH ASSOCI-ATE position available for an individual to study mamn-malian fertilization at the Population Council's Centerfor Biomedical Research located on the campus ofRockefeller University. The research to be undertakenwill depend on the iterests and qualifications of theindividual who is chosen. Send curriculum vitae and thenames of three references to or contact: Dr. David M.Phillips, The Population Council, Center for Bio-medical Research, 1230 YorkAvenue, New York, NY10021; telephone: 212-570-8744.

Johns Hopkins School of Medicine. POSTDOC-TORAL RESEARCH POSITION immediately avail-able to study the regulation of acetylcholine receptors(AChRs) in skeletal muscle cells in a variety of modelsystems in vivo and in culture. Ph.D. or M.D. and someprevious research xrience requed. Opdortunityavailablc immediately tor eulficd person. Sena curricu-lum vitae and names of three references to: Daniel B.Drachman, M.D., Department of Neurologv, JohnsHopkdns School of 'Medicine, 600 North WolfeStret, 5-119 Meyer Building, Baltimore, MD 21205or call 301-955-5406.

RESEBARCH ASSISTANT Ph.D. to study molecu-lar mechanisms of B cell development and genetics ofdifferentiation. Experience in moFecular genetics, recom-binant DNA technology, primary tissue explanation andlong term tissue culture, preparation of dendritic cellsand helper T cells, and a working knowledge of immu-nology, bacteriology and virology required. Qualifiedpersons contact: Johanna A. Griffin, Department ofMicrobiology, University ofAlabama at BirminghBirmingha, AL 35294.

RESEARCH ASSISTANT PROFESSOR positionavailable, Thyroid Laboratory, Department of Medicine,University of Miami School of Medicine. Requires aPh.D. in areas of molecular biology with proven back-jound in investigation of mechanism of action ofpolypeptide hormones. Salary $32,000 to $36,000. Sendresume and three letters of reference to: Mrs. ArleneGunn, Department of Medicine (R-760), P.O. Box016760, hliami, FL 33101. Equal Opportunity/Affirma-tive Action Employer.

Stanford University-RESEARCH ASSOCIATE-The Division of Clinical Pharmacology has a vacancy foran analytical chemist/pharmacokineticist to participate instudies of anti-HIV agents. Candidates should hold aPh.D. degree and have training in analytical methodsincluding HPLC and pharmacokinetic analysis. Thisposition is funded by the Stanford AIDS Clinical TrialsUnit. Send curriculum vitae and the names of threereferences to: Dr. Terrence F. Blaschke, S-169, Stan-ford Medical Center, Stanford, CA 94305-5113. AnEqual Opportunity Employer through Affirmative Action.

RESEARCH ASSOCIATE: Research biochemist/neurochemist position available to study the process ofmyehination at the molecular level. Three to 4 years ofpostdoctoral experience required in protein purification/characterization, protein sorting/targeting, tissue culturc,and recombinant DNA technology. Scnd curriculumvitae and references to: Dr. Gihan ennekoon, Depart-mcnt of Neurology, Mqeyr 6-119, The Johns HIopDkins University School ofMedicne, 600 North WolfeStreet, Baltimore, MD 21205.

RESEARCH ASSOCIATE. Conducting researchinto the biochemical nature of normal and diseasedarticular cartilage; investigating cartilage matrix structureand function, with special interest in the proteoglycanmolecules, using various biochemical techniques such asgel chromatography and electrophoresis as well as histo-chemical techniques; developing new techniques to studycartilage and proteoglycan structure; monitoring the lossof cartilage components during the process of fibrilla-tion; studying knee stability and the role of osteophytesin osteoarthritis; assisting in the design of a goniometerto be used in knee replacement surgery to measureinstabilities of the knee; preparing research findings forpublication attending and participating in the varioustcaching conferences and academic meetings of the Or-tho0a *c Surgery Department. Applicant must have anM.D. degree in medicine as well as 1 year of experience asa Research Associate or 1 year ofexperience as a Residentin Orthopaedic Surgery. Experience must have includedorthopaedic resear in the area of diseased cartilage orligaments. Will accept a plicants whose functional titlemay have been "medica officer" rather than "resident".Forty hours per week, Monday to Friday, with noovertime, 9:00 a.m. to 5:00 p.m.; $24,500 per annum.Send resume to: The Illinois Department of Employ-ment Security, 401 South State Street-3 South, Chi-cago, IL 60605. Attention: Marie Ninneman, Refer-ence #8671-N. An employer-paid ad.

RESEARCH ASSOCIATE, spring 1989 to investi-gate the role of sex steroids in bone cell biology. Postdoc-toral experience in molecular biology and cell cultureneeded for collaboration with a group of endocrinolo-gists/cell biologists. Appointment 1 to 3 years. Academicrank for salary ($23,000 to $28,000) depend uponexperience. Send curriculum vitae and letters of referenceto: Dr. Eric Orwoll, Oregon Health Sciences Univer-sity (L346), 3181 Sam Jackson Park, Portland, OR97201. OHSU is an Equal Opportunity Employer.

RESEARCH ASSOCIATE: Ph.D. in biochemistrywith three or more years of experience. Background incell separation and cell biology. Salary commensuratewith expenence and training. Send resume with letters ofrecommendation to: Dr. Vayne L. Ryan, University ofNebraska Medical Center, Department of Obstetricsand Gynecology, 42nd and Dewey Avenue, Omaha,NE 68105. Application deadline 15 February 1989.Equal Employment Opportunity/Afirmative Action Employer.

Several RESEARCH ASSOCIATE AND POST-DOCTORAL FELLOW positions in the area of vascu-lar smooth muscde excitation-contraction coupling areavailable for January and July 1989 for work with amultidisciplinary group whose activities include musclemechanics, ion transport, phosphoinositide metabolism,laser photolysis ofcaged-compounds, fluorescent analysisof cell ions, cellular eectrophysiology, contractile proteinbiochemistry and cell biology of contractile and cytoskel-etal proteins. Interest and experience in these areas willbe beneficial. Applicants should send their curriculumvitae, names of references, and a summary of researchexperience and goals to: Robert H. Cox, Ph.D., Direc-tor, Bockus Research Institute, The Graduate Hospi-tal, One Graduate Plaza, Philadelphia, PA 19146.Afirmative Action/Equal Opportunity Employer.

RESEARCH PLANT PHYSIOLOGIST: EPA En-vironmental Research Laboratory, Corvallis, Oregon.Seeking a quantiative physiological ecologist to conductresearch in effects of air pollutants on terrestrial ecosys-tems. This is a full-time GM-14 position and requires aPh.D. in quantiative ecolo lant physiology, forestsciencc, or a dosely related disciplne Candidates mustbe able to demonstrate the following skills: (i) an abilityto plan, implement, and lead complex research programs;(ii) experience in developing ecological and physiologicalprocess models, in particular with tree species; and (iii)proven ability to communicate research results bothorally and in the peer reviewed literature. Position onlyopen to U.S. citizens. Salary range: $48,592, to $63,172per annum. For technical infonnation on this positioncontact: Dr. Robert T. Lackey at the Corvallis Labora-tory: 503-757-4634/4600. To obtain a complete va-cancy announcement, application package, and instruc-tions, write: EPA Personnel Office, P.O. Box 98516,Las Vegas, NV 89193-8516 no later than 30 Decem-ber 1988.

EPA is an Equal Opportunity Employer.

RESEARCH ASSOCIATE: supervises laboratorypersonnel in ultracentrifugation and lipid chemistry,lipid/lipoprotein research, use of radioisotopes. RequiresM.S. and 4 years of experience or 4 years as researchassistant/researcher; minmum of 2 years of lipoproteinmethodology experience, supervisory experience in thedevelopment of new methodology, anal sis of results andmanuscript preparation. Fortyhours, 9 a.m. to 5 p.m.,$21,850 per year. Send rcsume to: Job Service ofFlorida, 701 SW 27 Avenue, Mezzanine Floor, Mi-ami, FL 33135-3014, Job Order No.: FL-5571981.

The U.S. Department of Agriculture, AgricultrualResearch Service (ARS), Fort Collins, Colorado, seeksqualified candidates preferably with a Ph.D. degree inrange management, soil science, plant physiology, ordirecly related discipline for a RESEARCH LEADER-SHIP POSITION at the GM-14/15 level. Incumbentwill provide leadership to an interdisciplinary team ofscientists and conduct personal research to increase theefficiency of crop, forage, and livestock productionthroughintegrated management of genetic, land, water,and atic resources. pplicants must meet specificeducation requirements plus professional experience di-rectly related to the position. Selectee will work incooperation with university scientists and supervise andassist subordinate scientists in interpreting and publish-ing their research. Knowledge of crop and livestockproduction systems and skill in conducting independentresearch are required, as is knowledge of systems ap-proaches and computer applications to agricultural prob-lems and skill in managing human, physical and financialresources. ARS offers competitive salaries, excellentbenefits program and superb working facilities. RockyMountains location offers abundant recreational oppor-tunities. For job information, contact: Dr. ThomasArmy, 303-229-5500. For vacancy announcement andjob application forms, contact: C. Enuton, 301-344-3138, or write: Personne Division, Room 403, Build-ing 003, BARC-West, Beltsville, MD 20705. Inquir-ies must be received by 20 December 1988. Codeapplication: 9W006. Sala based on experience: GM-14, $46,679 to $60,683; GM-15, $54,907 to $71,377.Must be a U.S. Citizen. An Equal Opportunity Employer.

Rhode Island Hospital seeks a RESEARCH SCIEN-TIST with a Ph.D. in molecular biology (preferably) orbiochemistry. Candidates must qujalify for a position onthe medical faculty of Brown University as AssistantProfessor of Medicine (Research). One or 2 years ofresearch training beyond the Ph.D. is recaured. Thesuccessful candidate will develop a research programfocused on the molecular biology of control of vascularsmooth muscle tone with emphasis on the coronarycirculation. This person is expected to collaborate doselywith other faculty currently conducting related researchin the area. Interested candidates should send curriculumvitae and a one page description of research interests by31 December 1988 to: Henry Gewirtz, M.D., Chair-man, Scarch Committee, Division of Cardiology,Rhode Island Hospital, 593 Eddy Street, Providence,RI 02903. Rhode Island Hospital is an Equal EmploymentOpportunity/Afirmative Action Employer and actively solicitsapplications from minority and protected groups.

RESEARCH SPECIALIST to perform research inongoing projects: development of genetically engineeredplants hang desirable heavy metal accumulation andaccommodation characteristics, and development ofplants having improved insect resistance. Specific dutiesindude preparation of transformation vectors, transfor-mation of plants, detection of gene products, and assess-mcnt of physiological effects of transformation. Must beproficient in recombinant DNA methods, electropora-tion, plant transformation, analysis of gene expression,immunological and enzymological methods, HPLC,atomic absorption spectroscopy, radiolabeled metalbinding assays, and plant, plant cell and tissue culture. APh.D. degree in biochemistry or molecular biology andat least 3 years of relevant postdoctoral experience arerequired. Forty hours per weck, $22,000 per year. Sendr6sumi to: T. Moore, KY705865, Dcpartment forEmploymcnt Services, 300 South Upper Street, Lex-ington, KY 40508.

SCIENCE, VOL. 242I094.

POSITIONS OPEN POSITIONS OPEN

CHAIRMANDepartment of Anatomy

The University of Pennsylvania School ofMedicine is seeking applicants for the position ofProfessor and Chairman of the Department ofAnatomy.

Application is invited from individuals withoutstanding achievement in research, demon-strated leadership ability, and appreciation for therole of a department of anatomy in educating bothmedical and graduate students. We are seekingcandidates from a broad spectrum of disciplinesand departments related to anatomy and cell,structural, neuro and developmental biology.The University is an equal opportunity,

affirmative action employer. Women and minoritycandidates are encouraged to apply.

Interested applicants should send curriculumvitae to:

Giuseppe G. Pietra, M.D.Chairman, Anatomy SearchCommittee

Professor, Department of Pathology& Laboratory Medicine

University of Pennsylvania Schoolof Medicine

6th Floor Founders Pavilion< Philadelphia, PA 19104-4283

THE

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Film (right-reading, emulsion face down) or full camera ready art and insertion order must reach: SCiENCE, Short Close Desk, 1515Broadway, New York, NY 10036 by NOON Mondays (except for legal holidays when material must reach New York by Noon Fridays).Because space is limited, the four-day close page will be reserved on a first-come, first-served basis, at a 15% premium. 1/4 and 1/2page ads only.

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PHD SCIENTISTS& ENGINEERS

APPLY FOR RESIDENT & POST-DOCTORAL ASSOCIATESHIP AWARDSUnique opportunities for independent

research in the fields of:* CHEMISTRY * PHYSICS* EARTH & ATMOSPHERIC SCIENCES* ENGINEERING, MATHEMATICS &APPLIED SCIENCES

* LIFE & MEDICAL SCIENCES & BIOTECHNOLOGY* SPACE & PLANETARY SCIENCESThe National Research Council in cooperation with 30selected federal laboratories announces three competi-tions in 1989 for approximately 450 research awards forindependent scientific research. Recipients will be freeto pursue research problems of their own choice as guestinvestigators at the federal laboratories. Duration of awardis one year renewable to three. Annual stipend for recentPh.D's vary from $27,150 to $35,000, depending upon theprogram sponsor, and are appropriately higher for seniorresearchers. Relocation reimbursement and funds for pro-fessional travel on tenure are available, and a healthinsurance program is provided.For further information and application materials write to:

Associateship Programs (GR 430A1S4)NATIONAL RESEARCH COUNCIL2101 Constitution Avenue, NW.

Washington, DC 20418Deadlines for application are: January 15

(December 15 for NASA), April 15 and August 15

M.W.=m

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POSITIONS OPEN

RESEARCH ASSOCIATE, POSTDOCTORAL,ORMASTER'S DEGREE WITH EXPERIENCE tostudy theoretical (evolutionary biology, ecology) andapplied (fisheries biology) molecular population geneticsof marine vertebrates and invertebrates. Expenence intechniques of obtaining, and analysis of, mitochondrialor single-copy DNA restriction fragment patterns isrequired. Knowledge of DNA sequencing techniquesand proven publication ability is desirable. Position isavailable at a multidisciplinary research facility with astate-of-the-art molecular genetics laboratory. Salary is$22,000 to $25,000 per annum, benefits not induded.Send curriculum vitae, names of three references, recentpublications, and transcripts if graduated within the past3 years, by 20 December 1988 to: Personnel OficeFlorida Marine Research Institute, 100 Eighth Ave-nue Southeast, St. Petersburg, FL 33701. An EqualOpportunity/Afirmative Action Employer.

SCIENTIFIC DIRECTORFor new drug company. Ph.D. in biological sciences or

M.D. required, as well as prior hands-on research experi-ence in vascular disease and/or lipid and lipoproteinmetabolism. Will work dosely with V.P. of Develop-ment. Involves working with sophisticated scientific ad-visory board, maintainng and developing contact andrelations with key research centers m the U.S. andabroad. Exciting environment and people with equityparticipation. Send resume to: Cholestech Corpora-tion, 3100 Diablo Avenue, Hayward, CA 94545.

SECTION HEAD, Museum Education, Museum ofScience, Boston, Massachusetts. Applications are invitedfor this senior level management position where you willbe responsible for a broad variety of internal educationalprograms. Responsible for Courses and Lectures, SchoolPrograms, Public Programs, and Volunteer Services inMuseum with 2 million visitors annually. You willsupervise 40 full-time staff and a budget of $2 million.S range in the $40's. Excellent benefits. The success-ful candidate will possess an M.S. degree, minimum of 5years of experience in science museum education andmanagement, strong interpersonal skills, and commit-ment to object-based informal science education. Sendletter of application and resume by 1 December 1988 to:Helen P. Hailer, Human Resources, Boston Museumof Science, Science Park, Boston, MA 02114.

Washington and Jefferson College, a 1200-studentliberal arts college in southwestern Pennsylvania, withapproximately 200 biology majors, is adding a STAFFPOSITION in molecular biology. Departmental dutieswill include developing and teaching courses in molecu-lar biology and experimental biology, participation in thebeginning course, supervising independent studies, andadvising. Experimental biology should be molecular inorientation and might incude more in-depth work inareas such as recombinant DNA techniques, monoclonalantibody procedures, molecular separations, sequencing,etc. Applicants should send resumrs to: The ExecutiveAssistant to the President, Washington and JeffersonCollege, Washington, PA 15301. No references unlessrequested. Affirmative Acion/Equal Opportunity Employer.

SYSTEMATIC ENTOMOLOGISTThe Field Museum of Natural History seeks an out-

standing scientist for a career track position as Assistantor Associate Curator of Insects in the Department ofZoology. The Field Museum's Entomology Collectioncontains more than 9 million specimens, and is particu-larly strong in holdings of Coleoptera and leaf-litterarthropods. The successful candidate will: (i) have aPh.D.; (ii) have demonstrated a productive research andfield program in systematic or evolutionary entomology;and (iii) have experience with curatorial procedures andmaterials used in entomology collections. In addition todeveloping and maintaining a world-dass, innovativeresearch program, responsibilities indude curation forsome portion of the collection. The potential exists forparticipating in graduate and undergraduate training atthe University of Chicago. Please send by 5 January1989, curriculum vitae, copies of publications, a state-ment of research objectives, and three letters of recom-mendation to: Dr. B. Chernoff, Chairman-SearchCommittee, Division of Fishes, Field Museum ofNatural History, Roosevelt Road at Lake ShoreDrive, Chicago, IL 60605. The Field Museum ofNaturalHistory is an Equal Opportunity Employer.

SABBATICAL POSITION-Funds are available toprovide partial support for an individual wanting tospend a Sabbatical Leave in a laboratory studying proteintoxins that act on the nervous system. The successfulapplicant will join a multidisciplinary research teamcomposed of persons from medicine, microbiology,pharmacology, physiology and neurology. The new per-son will have an opportunity to leam and apply numer-ous techniques, ranging from protein chemistry to mi-cropharmacology. Facilities include a gas phase sequena-tor, a peptide synthesizer, fluorescence microscopy andFACS, electron microscopy, electrophysiological meth-ods for patch damp analysis, a variety of isolated tissuepreparations, tissue culture and monoclonal antibodyfacilities, etc. Positions are available for spring andsummer of 1989. Interested persons should submitcurriculum vitae, list of publications, and names ofreferences to: Dr. Lance L. Simpson, Jefferson MedicalCollege, Thomas Jefferson University, 1025 WalnutStreet, Philadelphia, PA 19107. An Aftfirmative Action!Equal Opportunity Employer.

Louisiana State University (LSU) Eye Center is look-ing for a SENIOR PHARMACOLOGIST. Applicantshould be interested in drug delivery systems althoughother areas of research will be considered.

Previous experience in ophthalmology not necessary.Interested applcants send curriculum vitae to: Herbert E.KM.D., LSU Eye Center, 2020 Gravier Street,

Siite B, New Orleans, LA 70112. LSUMC is an EqualEmployment Opportunity/Afirmative Action Employer.

The Department of Biology, Hartwick College, invitesapplications for a full-time, TENURE-TRACK POSI-TION in developmental biology. Teaching responsibil-ity will include a course in Developmental Biology formajors and nonmajors, comparative anatomy, generalbiology. Other responsibilities include directing under-graduate research in animal development. Applicantsshould have a strong background in molecular biologyand be committed to teaching at the undergraduate level.Ph.D. (or near completion) required. Rank and salarycommensurate with experience. Send letter of applica-tion, resume and three letters of reference by 9 December1988 to: M. Richard Segina, Chair, Department ofBiology, Hartwick College, Oneonta, NY 13820. AnEqual Opportunity Employer.

The Department of Biology at the University ofSouthwestern Louisiana (USL) invites applications forFOUR TENURE-TRACK POSITIONS in supportof the doctoral program in Environmental and Evolu-tionary Biology. Faculty are expected to participate inundergraduate and graduate instruction, direct graduateresearch and demonstrate competence in research andgrantsmanship.The biology faculty currently numbers 25 with re-

search ranging from molecular to ecosystem studies.USL has an exceptionally well-equipped Electron Mi-croscopy Center and a Center for Advanced ComputerStudies. Other resources indude the Primate ResearchCenter, the Center for Crustacean Research, the Louisi-ana Universities Marine Consortium (LUMCON) ma-rine laboratory and research vessels, and affiliation withthe U.S. Fish and Wildlife Service's National WetlandsResearch Center.We are seeking qualified individuals in the following

areas:DEVELOPMENTAL BIOLOGY-research area

open.IMMUNOLOGY-research area open.MICROBIOLOGY-research interests may include,

but are not limited to, plant-microbe interactions and/orgenetics.WILDLIFE AND RESOURCE BIOLOGY-re-

search interests may indude, but are not limited to,remote sensing, landscape modeling and restoration,wildlife toxicology and nutrition, and biometrics.Send curriculum vitae, selected reprints, a concise

statement of research goals, and names, addresses andtelephone numbers of three referees. Review of applica-tions will begin 1 December 1988 and continue untilpositions are flled. Direct application to: Faculty Devel-opment Search Committee, Department of Biology,University of Southwestern Louisiana, Lafayette, LA70504-2451. Affirmative Action/Equal OpportunityEmployer.

THE HISTOCHEMICAL SOCIETYANNUAL MEETINGOrlando Marriott Hotel

Orlando, Florida31 March to 2 April 1989

For further information, registration and housingforms, please contact:

The Histochemical SocietyRegistration Supervisor

6900 Grove RoadThorofare, NJ 08086-9447

PROGRAM

DOCTORAL PROGRAM IN MICROBIOLO-GY seeks quality candidates to study molecular genetics,cell biology, virology, immunology, pathogenic microbi-ology, microbial biochemistry, biotechnology, and ap-plied and environmental biology in a cooperative pro-gram between Rutgers, The State University of NewJersey, and the University of Medicine and Dentistry ofNew Jersey. Seventy-five faculty from various universitydepartments, research centers and institutes participate inthe program to provide excellent research training andemployment opportunties. Fellowships, assistantshipsand scholarships provide up to $11,000 stipend plustuition to qualified applicants on a competitive basis.Contact: Dr. Alan D. Antoine, Graduate Program inMicrobiology, Rutgers University, P.O. Box 231,New Brunswick, NJ 08903. Telephone: 201-932-9881. An Afirmative Action/Equal Opportunity Employer.

FELLOWSHIPS

POSTDOCTORAL FELLOWSHIP

Fellowships are available, supported by an Institution-al National Research Service Award (NIH), in the area ofLipid/Lipoprotein Metabolism and Cardiovascular Dis-ease. Research topics include regulation of hepatic pro-duction and secretion of lipoproteins, regulation of fattyacid oxidation and carnitine palmitoyltransferase regula-tion of cholesterogenesis, phosphoinositides and calciumin transmembrane signaling, metabolic aspects of lipidabsorption, autonomuc mechanisms and vasoactive pep-tides m arachidonic acid and prostaglandin metabolism,regulation of lipoprotein-lipase, mechanisms of reversecholesterol transport, and regulation of lipolysis in adi-pocytes. First-year stipends are $20,000. Applicants mustbe U.S. citizens or permanent residents. Please send curricu-lum vitae and names of three references to: MurrayHeimberg, Ph.D., M.D., University of Tennessee,Memphis, The Health Science Center, Memphis, TN38163. Women and minorities are encouraged to apply. TheUniversity of Tennessee is an Equal Opportunity/AffirmativeAction Employer.

POSTDOCTORAL FELLOWSHIPS IN ENVI-RONMENTAL TOXICOLOGY AND PATHOLO-GY are available at Northwestern University MedicalSchool (NIH training grant). The preceptors and theirresearch areas are: Toshio Narahashi (Mechanisms ofaction of insecticides on neuronal ion channels by patchclamp); Philip Iannaccone (Effects of carcinogens onmammalian embryo); Michael Morin (Antineoplasticagents; Signal transduction and therapeutic application);Ryoichi Oyasu (Mechanisms of urinary bladder cancer);M. Sambasiva Rao (Pancreatic carcinoma); JanardanKI Reddy (Pancreatic carcinoma and liver peroxisomeproliferators); Dante G. Scarpelli (Mechanisms of pan-creatic carcinoma); Jerome Seidenfeld (Polyamines:Biosynthesis inhibitors and role in growth regulation);Dennis Solt (Carcinogen modification of epithelialcells); Chau H. Wu (Action of environmental toxins onnerve membranes by patch clamp). The applicants must beU.S. citizens or permanent residents. Send a letter stating aspecific area of interest, curriculum vitae, and threereference letters to: Dr. Toshio Narahashi, ProgramDirector, Departnent of Pharmacology, Northwest-ern University Medical School, 303 East ChicagoAvenue, Chicago, IL 60611. Telephone: 312-908-8284. An Affirmative Action/Equal Opportunity Employer.

SCIENCE, VOL. 242io96

MEETINGPOSITIONS OPEN

Section ManagerI

Immunology/Dermatology 89 90 91

Immunology/Dermatology Anticipated hiring neds

We are currently seeking a qualifled candidate to fill the newly created position of Sec-tion Manager, Immuno-Dermatology. The Section Manager will lead a group of 2-3scientists involved in conducting high-quality research of Immunological phenomenarelated to dermatological diseases and the effect of drugs on these phenomena. A PhDin Dermatology or Immunology and at least 5 years of research experience is required.In addition to the above position, we are currently expanding our scientific staff andhave a number of exciting career opportunities available for scientists with the follow-ing expertise:

* Research ScientistPhD In Immunology required. Responsibilities will involve conducting research incellular immunology. Post doctoral experience preferred.

* ScientistPosition requires an MS degree in Biological science with 2 or more years experienceIn molecular biology and biochemistry. Experience In bone research is useful. Positionwill include studying the growth regulation of cells using molecular approaches.Rorer offers the opportunity for professional growth, a competitive salary, fully paidbenefits package and a pleasant work environment. Qualified candidates shouldrespond to the positlon titles ginen above. A detailed resume Including salary historyshould be forwarded to Linda L Stewart, Pesonnel Manager, Rore Central Rsarch,640 Alendale Road, King Of Prussia,PA 19406. An Equal Opportunity Employer, M/FNIH.

Rorer Centrl ResearchBuilding for the future with excellent people,quality programs and sense of urgency.

RUTGERS, THE STATE UNIVERSITYOF NEW JERSEY

ANDTHE UNIVERSITY OF MEDICINE AND

DENTISTRY OF NEW JERSEYROBERT WOOD JOHNSON

MEDICAL SCHOOL

Announce a Shared InterdisciplinaryCore Curriculum in

MOLECUIAR AND CELL BIOLOGYThe Graduate Programs of Rutgers University and UMDNJ-Robert Wood Johnson Medical School are seeking out-standing applicants for this interdisciplinary curriculum.Successful applicants will be awarded a fellowship pro-viding an annual stipend of $12,000 plus tuition. Studentswill take a program of interdisciplinary courses, seminars,and research laboratory rotations. Research opportunitiesin Molecular and Cell Biology exist in all participatinggraduate programs of both universities, including the NewJersey Center for Advanced Biotechnology and Medicine,Waksman Institute, and Center for Agrcultural MolecularBiology. Students will obtain the Ph.D. degree from theprogram in which they do their research project.

Students interested in applying or receiving further infor-mation should wrte to:

Michael J. Leibowitz, M.D., Ph.D.Director, Core Curriculum In Molecular and Cell BiologyDepartment of Molecular Genetics and MicrobiologyUMOMI-Robert Wood Johnson Medical School675 Hoes LanePiscataway, Mew Jersey 088354-5635

An Equal Opportunityl/AFIrmative Action Employer/MIF/H/V

POSTDOCTORAL FELLOWSHIPSThe Imperial Cancer Research Fund is one of the largest Independent cancer research Institutes in Europeemploying approximately 400 scientists and clinicians. It has a wide ranging programme in fundamental, appliedand clinical cancer research.There are approximately seventy research groups encompassing the major disciplines of cellular and molecularbiology including biochemistry, genetics, immunology, and virology. Most are housed at the main building inCentral London; there are also research units at Clare Hall, North London and at Dominion House attached to St.Bartholomew's Hospital. ICRF's external clinical units based in major teaching hospitals form the link betweenfundamental research and clinical activities.Each research group works independently. All have access to centralized services including cell production,oligonucleotide and peptide synthesis, amino acid and DNA sequencing, a library of DNA probes and somatic cellhybrids for gene mapping, experimental animal breeding and maintenance including transgenic mice, electronmicroscopy, and a large computer facility.Approximately 40 posdoctoral fellowships are available each year to scientists of any nationality. Most of theseare three year fellowships, but visiting fellowships for a period of one or two years, are offered. Salaries forpostdoctoral fellows are in the range of £12,500-16,000, dependent on age and experience.Further information on the research interests of the groups and details of projects currently available may beobtained from;

Mrs. P. HarwoodPersonnel Department

Imperial Cancer Research FundP.O. Box 123

London WC2A 3PX, UKFax No: 011441 242 1510

quoting ref. no. 1/RClosing date for applications: 9th December, 1988

Staff Scientists: Sir Walter Bodmer (Director of Research), D. Altman, J. Armstrong, F. Balkwill, D. Bentley, J.Bodmer, D. Cantrell, L. Crawford, A. Creighton, M. Crumpton, J. Cuzick, P. Darbre, N. Dashpande, C. Dickson,G. Evan, J. Fox, M. Fried, A.M. Frischauf, S. Gendler, S. Goodboum, S. Goodfellow, R. Hallowes, J. Hart, B.Hill, G. Hodges, N. Hogg, M. Horton, N. Jones, P. Karran, J. Kemshead, I. Kerr, R. King, H. Land, B. Lane, D.Lane, A. Lee, K. Lee, H. Lehrach, T. Lindahl, M. Meuth, C. O'Neill, M. Owen, M. Parker, G. Peters, J. Rothbard,C. Rowlatt, E. Rozengurt, D. Sheer, E. Solomon, G. Stark, J. Taylor-Papadimitriou, N. Telch, P. Thorpe, J.Trowsdale, R. Treisman, D. Tucker, D. Wang, R. Watson, F. Watt, S. West, J. Williams, R. Wolf, R. Wood, N.Wright, B. Young.Smoking is actively discouraged.

I M P E R I A LCANCER RESEARCH FUND

Sr. ScientistInsect Research

The Basic Insect Research Depart-ment of Zoecon Research Institute,a division of Sandoz Crop Protec-tion Corporation, is seeking an ex-perienced Ph.D. scientist to workwithin an interdisciplinary re-search team studying insect neu-ropeptide systems.

Work areas include:1. Enzymology of post-transla-

tional processing of proteinsto active neuropeptides.

2. Hormone receptor systems.

To apply for this position, sendyour curriculum vitae and names ofthree references to:

Sandoz CropProtection CorporationZoecon Research InstituteHuman ResourcesDept., #87-341975 California AvenuePalo Alto, CA 94304-1104

AAIEOE

0r,

LI

FELLOWSHIPS

FELLOWSHIP IN CARDIOVASCULAR PA-THOLOGY. Diagnostic training involves rigorous as-sessment of autopsy and surgical specimens derived fromthree major hospitals. Research training is available in anextraordinary environment that includes widely recog-nized and strongly interdigitated research programs incardiovascular pathobiology. Applicants should havecompleted basic traing in anatomic pathology. For-ward curriculum vitae and statement of career goals to:Jdefrey E. Saffitz, M.D., Ph.D., Department ofPathology, Washington University, 660 South EucidAenue,S3t. Louis,MO 63110.

OPENINGS FOR SCIENTISTSThe Weizmann Institute of Scicnce is now offering a

limited number of temporary appointments to the posi-tion of scientist.

Candidates must have completed 2 years of postdoc-toral work.Appointments will be made in all the areas of scientific

research at the Institute.Biology PhysicsChemistry MathematicsBiochemistry-Biophysics Science TeachingAppointments are for a period of 1 year, however, they

may be extended for a penod not to exceed 5 years fromreceipt of Ph.D. degree (or equivalent). Successful ap-pointees will be eliible to apply for promotion to theposition of senior scientist.

Financial renumeration for a scientist is at the level oflecturer and indudes all of the associated benefits. Inaddition, a relocation stipend is provided.

Application forms and additional information may beobtained from:

The Fcinberg Graduate SchoolThe Weizmann Institute of Science

Rehovot, 76100 IsraelApplications are reviewed twice each year:

1 January and 15 May.

POSTDOCTORAL FELLOWSHIPSIN THE DEPARTMENT OF ANATOMY

AND NEUROBIOLOGYUNIVERSITY OF CALIFORNIA, IRVINESeveral positions for research in individual laboratories

in the Department are available for candidates who havedemonstrated research promise at the predoctoral orpostdoctoral level. The emphasis of research in theDepartment is in the Neurosciences with special expertisein neuromorphology, sensory physiology, and molecularneurobiology. The faculty of the Department and theirresearch interests are:Dr. Robert Blanks: Eye movement control, physi-

ology of upper airwayDr. James Fallon: Chemical neuroanatomy,

transmitters and growth fac-tors

Dr. Christian Gall: Limbic/olfactory anatomy,neuropeptides, neurochemi-cal plasticity

Dr. Roland Giolli: Visuomotor systemDr. Steward Hendry: Primate visual systemDr. Paul Isackson: Molecular neurobiologyDr. Edward Jones: Sensory-motor anatomy and

physiologyDr. Leonard Kitzes: Auditory system anatomy and

pysiologyDr. Charles Ribak: Epilepsy, neurotransmitters

anid circuitsDr. Richard Robertson: Thalamocortical developmentDr. Malcolm Semple: Auditory processingDr. John Swett: Spinal cord and peripheral

nervous systemDr. Yasuhiro Torigoe: Periphera nervous system

and oculomotor controlApplications or inquiries for additional information

should be sent to:Dr. Edward G. Jones, Chairman

Department ofAnatomy and NeurobiologyUniversity of CaliforniaMed Surge II, Room 364

Irvine, CA 92717An Affinmative Action/Equal Opportunity Employer.

I098

POSTDOCTORAL FELLOWSHIP in intracellularcalcium, biochemistry, molecular biology, genetics, renalmetabolism and hypertension is av aiSble immediatelythrough an NIH Research Training Program at theMedical College of Virginia (MCV). Salary $24,000 to$27,000 plus travel, tuition and other benefits. Opportu-nity for professional growth. Candidate must have aPh.D., M.D. or equivalent degrees and be a permanentresident or citizen of the United States. Applicantsshould send curriculum vitae, concise statement of re-search interest, and the names of three references to: Dr.J. C. M. Chan, Box 498 MCV Station, Richmond,VA 23298-0498.

POSTDOCTORAL FELLOWSHIP. We invite in-quiries from candidates with a Ph.D., M.D./Ph.D. orM.D. for a 3-year postdoctoral fellowship in immunolo-gy. The laboratory studies the biochemical regulation ofhuman T lymphocyte immune effector functions inhealth and m autoimmune disorders. This position issupported by an NIH training grant. Please addressinquines accompanied by curriculum vitae to: Gary M.Kammer, M.D., Division ofRheumatic Diseases, De-partment ofMedicine, University Hospitals of Cleve-land, 2074 Abington Road, Cleveland, OH 44106.

POSTDOCTORAL FELLOWSHIPSThe Feinberg Graduate School of the Weizmann

Institute of Science is now offering Postdoctoral Fellow-ships in the following fields of study:Biology PhysicsChemistry MathematicsBiochemistry-Biophysics Science TeachingThese Fellowships are intended for young scientists

who have recently received a Ph.D. degree.The fellowship provides a 12-month stipend (with

COL adjustments), a relocation allowance, and airfare toIsrae. If the Fellowship is renewed for a second year,return airfare is provided.

Application forms and additional information may beobtained from:

The Feinberg Graduate SchoolThe Weizmann Institute of Scicnce

Rehovot, 76100 IsraelApplications are reviewed twice each year:

1 January and 15 May.

PREDOCTORAL FELLOWSHIPS are availablefor studies leading to the Ph.D. in the PhysiologyGraduate Program in the Temple University School ofMedicine. Stipends and tuition waivers are available foreligible candidates. Specific research topic areas includecel biology of normal and diseased myocardium, mem-brane receptors, developmental cardiopulmonary physi-ology, liquid ventilation, underwater medicine, mem-brane transport, gastrointestinal function, vascularsmooth muscle, chemoreceptor function, and control ofmicrocirculation. Applications may be sent to: Steven R.Houser, Ph.D., Director, Physiology Graduate Pro-gram, Box 1090, Temple Umversity School ofMedi-cine, 3420 North Broad Street, Philadelphia, PA19140. An Equal Opportunity/Afirmative Action Employer,MIF.

SURA/CEBAF GRADUATE FELLOWSHIPSIN NUCLEAR PHYSICS, ACCELERATORPHYSICS AND RELATED SCIENTIFIC

AND ENGINEERING FIELDSThe Southeastern Universities Research Association

(SURA), Inc., invites applications for graduate fellow-ships from full-time master's and doctoral students atSTJRA member institutions. SURA will make up to fiveawards of $10,000 each annually, based on a competitiveevaluation of the applicants' academic qualifications,proposed plan of study, research potential and relevanceto activities at the Continuous Electron Beam Accelera-tor Facility (CEBAF), Newport News, Virginia. Dead-line is 15 January 1989 for the 1989 to 1990 academicyear. Contact:

SURA/CEBAF Fellowship Progam1776 Massachusetts Avenue, N.W, #04

Washington, DC 20036Telephone: 202-457-0381

POSTDOCTORAL FELLOWSHIP. We invite in-quiries from candidates with a Ph.D., M.D./Ph.D. orM.D. for a 3-year postdoctoral fellowship in studies ofconnective tissue cells and matrix, and osteoarthritis,induding chondrocyte biology, and animal models ofardritis. This position is supported by an NIH traininggrant. Please address inquirnes accompanied by curricu-lum vitae to: Roland W. Moskowitz, M.D., Divisionof Rheumatic Diseases, Department of Medicine,Universitr Hospitals of Cleveland, 2073 AbingtonRoad, Cleveland, OH 44106.

C. H. BEST FOUNDATIONPOSTDOCTORAL FELLOWSHIPS

In diabetes research, molecular endocrinology, molec-ular biology, differentiation, reproductivc biology, im-munology, structure and function ofmembranes or lipidmetabolism. Tenable in the Banting and Best Depart-ment of Medical Research for 2 years after 1 July 1989with a competitive stipend. Available to new Ph.D.'s orcandidates with less than 2 years ofpostdoctoral trainingby 30 June 1989. Send curriculum vitae, transcripts, andthree letters ofreference, preferably before 30 November1988 to: Dr. Arnis Kuksis, Fellowship CommitteeChairman, Banting and Best Department ofMedicalResearc, University of Toronto, Toronto, CanadaM5G 1L6.

SMITHSONIAN FELLOWSHIPS INTROPICAL BIOLOGY

Several predoctoral, postdoctoral and senior postdoc-toral fellowships are available to conduct research at theSmithsonian Tropical Research Institute (STRI) in theRepublic of Panama. STRI is an international center foradvanced study in tropical biology (ecology, humanecology, paleoecology, evolution, behavior, plant physi-ology, molecular evohition) and archaeology. The Insti-tute has a permanent scientific staff of 26 and supportsvisiting scicntists and fellows. STRI facilities include: afield station at Barro Colorado Island and mainlandliving and working quarters in nearby Gamboa (tropicalmoist forest); living quarters at Fortuna in WesternPanama (montane forest); marine laboratories on thePacific and Atlantic coasts and a field station in theCaribbean, and a research library.

For applications, contact:Office of Fellowships and Grants

Smithsonan Institution, Drawer TBL'Enfant Plaza, Suite 7300Washington, DC 20560Telephone: 202-287-3271

Deadline: 15 January annually.

MARKETPLACE

Circle No. 45 on Readers' Service Card

SCIENCE, VOL. 242

ANTI-VIRAL DRUG TESTING FOR HIVPan-Data Sysems, Inc. (PDS), offers assist-ance in drug testing using freshly isolated mono-cyte/macrophage cultures and PHA-stimulatedleukocytes.Contact Dr. John Dahlberg, Director of Re-search, for more information:

13 Taft Court, Rockville, Md. 20850(301) 294-2297 fax (8095)

1 (800) 543-6059

FELLOWSHIPS FELLOWSHIPS

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Circle No. 169 on Readers' Service Card

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