th Qtr. 2019 BIOTECHNOLOGY STARTUPS RESEARCH REPORT · The Biotechnology Innovation Organization, or BIO, the largest biotechnology industry organization in the United States, subdivides

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GLOBAL BUSINESS CONFIDENCE REPORT 4th Qtr. 2019

BIOTECHNOLOGY STARTUPS RESEARCH REPORT 4th Quarter 2019

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Table of Contents Overview ........................................................................................................................................................................... 3

Industry Definition .......................................................................................................................................................................................... 3

Sectoral Definitions ........................................................................................................................................................................................ 3

Main Activities .................................................................................................................................................................................................. 4

Associated Industries ..................................................................................................................................................................................... 4

Industry at a Glance ......................................................................................................................................................... 5

Industry Overview ........................................................................................................................................................................................... 5

Industry Statistics ............................................................................................................................................................................................ 5

Key Trends .......................................................................................................................................................................................................... 5

Industry Outlook .............................................................................................................................................................................................. 5

Products & Markets ......................................................................................................................................................... 6

Demand Determinants .................................................................................................................................................................................. 6

Major Markets .................................................................................................................................................................................................. 7

Supply Chain ..................................................................................................................................................................................................... 8

Competitive Landscape ................................................................................................................................................... 9

Market Share Concentration ....................................................................................................................................................................... 9

Geographical Concentration ....................................................................................................................................................................... 9

Barriers to Entry ............................................................................................................................................................................................... 9

Consumer and Occupational Safety ...................................................................................................................................................... 10

Industry SWOT Analysis .............................................................................................................................................................................. 11

Reasons why BioTech Companies May Fail ........................................................................................................................................ 11

Financing of BioTech Firms ......................................................................................................................................... 13

Fund-Raising Over Time ............................................................................................................................................................................. 13

Investors ............................................................................................................................................................................................................ 14

Major Players ................................................................................................................................................................. 27

Early Stage BioTech Companies .............................................................................................................................................................. 27

National & International Industry Associations ................................................................................................................................ 35

Regional Industry Associations ................................................................................................................................................................ 37

Industry Trade Shows .................................................................................................................................................................................. 47

This custom research report was produced for ITC member – Enterprise Estonia.



Overview

Industry Definition The Biotechnology Innovation Organization, or BIO, the largest biotechnology industry organization in the United States, subdivides biotechnology into five areas1: • agricultural feedstock and chemicals

• drugs and pharmaceuticals • medical devices and equipment • research, testing and medical laboratories • bioscience-related distribution. Within the biotechnology sector, the life science industry includes the drug and pharmaceutical, and medical devices and equipment sectors of the biotechnology industry, and the pharmaceutical industry2. The North American Industry Classification System (NAICS) defines life science employment within the following categories: pharmaceutical manufacturing; research and development (R&D) in biotechnology; R&D in life sciences; analytical laboratory instrument manufacturing; and medical testing laboratories3.

Sectoral Definitions Early stage biotech start-ups No customers, employees or actual product needed; however there must be legitimate ideas for a tangible product of products based on a well-defined ‘pre-product’ and its associated IP. Here the pre-product could be a well studied and understood biomacromolecule of clinical relevance and the IP can include (but not limited to) industrial secrets, patents and expertise of key team members. Importantly, one must be able to at least theoretically bridge the pre-product with a product and its associated market. Further, an early stage startup is likely to have been in some form of existence for within ~3 years and has developed from a combination of government grants, funds from winning competitions (i.e. pitching comps), crowdfunding, potentially angel investors, and possibly small venture capital funding (if very lucky; this is quite rare and the investment is usually going to be around $500 000). Some may also call this the ‘seed’ stage which occurs before the early stage technically, and I would put the demarcation at if you have significant funding yet or not. Finally, it is quite normal for this stage to be cash-flow negative. Mid-stage biotech startups This is the growth phase of the company, where a well-defined market/s has been identified and one has moved past an initial prototype for the product. This is the stage where there will be employees (often on short-term contracts based on what you can afford), but not necessarily end-user customers (i.e. a patient). Here the customer focus is on larger, more well-established companies you would be looking to either partner with, sell your IP to or licensing your product to. Funding at this point will usually be from angel investors, venture capitalists (with the funds here increasing into the millions of dollars), and sometimes industry funding. The cash flow at this point would ideally be positive or neutral, though it may still be negative depending on the additional R&D expenditures required or investment in materials etc. This is the point of a company where equity will be given serious consideration.

1 Andres, G. (2017). Bioscience Innovation in the States: Legislation and Job Creation Through Public-Private Partnerships [Report]. 2 Anderson, P.L., Watkins, S.D. (2004). The Life Sciences Industry in Michigan: Employment, Economic and Fiscal Contributions to the State’s Economy. 3 Steele, E. (2017, August). Massachusetts Biotechnology Council Industry Snapshot 2017.



Late stage biotech startups A level of viability can be attributed to the company, and cash flows should be positive (though there can be rare exceptions to this). The product should now achieve a level of market penetration, and may indeed see end user sales occurring. This is the stage of a start-up where consideration to IPO’s and other investment instruments are imperative. Funding here may come from the sales of the product in addition to venture capital funding, leverage of IP (i.e. licensing contracts). In order to increase liquidity (for investor attractiveness), a company may stay at this stage for some time in order to strengthen their position (i.e. pay down certain debts, or expand a product range or the level of market penetration of the original product).

Main Activities Companies in this industry primarily use living organisms or molecular and cellular techniques to provide chemicals, food and services that meet human, animal or marine needs. The industry excludes companies involved in developing small-molecule pharmaceuticals, performing contract research or manufacturing biological equipment. Main activities of a biotech company may include: • DNA coding, mapping and sequencing • Processing biotechnologies • Subcellular organisms engineering • Cell and tissue culture engineering • Protein sequencing, synthesis and engineering

Associated Industries Text text text



Industry at a Glance

Industry Overview The Biotechnology in the US industry consists of Human health technologies, animal health, marine and terrestrial microbial technologies, environmental remediation and natural resource recovery, agriculture and aquaculture technologies and industrial technologies.

Industry Statistics Number of Organizations: 8,933 Number of Founders: 7,364 Average Founded Date: Dec 29, 2003 Percentage Acquired: 18% Percentage of Public Organizations: 9%

Key Trends Key trends for the biotech industry4: • Ageing populations • Growth of the middle-class • A need for more personalized medicine • Non-traditional players expanding into biotechnology • A greater role for nanotechnology in diagnostics, drug development, and drug delivery • Increased concern for drug safety • Climate change • Food security • Increasing scope, scale, complexity, and tempo of products • Societal views about biotechnology are improving • Open-sourcing of certain biotech research • Diversification of, and investment by, historical pharma companies into new areas of biotech

Industry Outlook The Biotechnology industry is growing quickly, characterized by a multitude of product applications and a wide range of burgeoning markets. Due to the industry's diverse nature, demand and revenue growth are supported by a similarly wide array of factors. Growing demand for ethanol indicates the increasing importance of crop yields to agricultural customers, which have consistently demanded industry products over the past five years and will likely continue to do so over the five years to 2024. Similarly, more than half industry revenue is generated by sales of healthcare products, and the aging US population has driven demand for that segment's products as a result of their growing medical needs.

4 Shamel, R. Double digit biotech growth continues. Genetic Engineering News. 2006 Feb



Products & Markets

Demand Determinants Increasing investment in the bioeconomy, complex societal challenges, the confluence of new technical drivers, and a proliferation of new actors are transforming both biotechnology products and the context in which the U.S. regulatory system operates. For this reason, it is important to track changes in multiple areas that may affect product development and penetration rates. To help set the stage about who and what is influencing the development of new biotechnology products, this section gives a brief overview of a number of these drivers and some of their possible effects on regulation of future products of biotechnology. Technical Drivers Several technical drivers have increased the rate at which new products can be developed and also increased the accessibility of modern tools of biotechnology, resulting in an increased number of actors who are able to create biotechnology products. Some key areas include DNA sequencing, synthesis, and editing; standardization of biological parts; and increasingly rapid design-build-test-learn cycles. • New Tools for DNA Sequencing, Synthesis, and Editing • Standardized Biological Parts • Increase in the Speed of the Design-Build-Test-Learn Cycle Additionally, the expansion of public and private biofoundries—centralized facilities that leverage software and automation to dramatically increase the number of organisms that can be engineered in parallel (Eisenstein, 2016)—is expected to have a substantial effect on the rate of introduction of biotechnology products to the marketplace, perhaps enabling academic laboratories and companies to complete development of multiple biotechnology products per year. Economic Drivers A second area of rapid change is in the economic drivers that underlie the development of new biotechnology products. Although difficult to accurately determine, total domestic revenues in 2018 from biotechnology—biological, agricultural, and industrial biotechnology products derived using genetically engineered (GE) organisms—have been estimated to be at least $483 billion and to have grown at a rate of more than 5 percent of U.S. Government Investment in Biotechnology Products: More than 40 countries, including the United States, have created national strategies or domestic priorities for developing and promoting a 21st-century bioeconomy5,6,7, 8. According to the Executive Office of the President’s Office of Science and Technology Policy, the bioeconomy is “research and innovation in the biological sciences [used] to create economic activity and public benefit”9. Governmental policies for promoting the bioeconomy seek to combine technological innovation, economic growth, ecological sustainability, and resource efficiency.

5 EC (European Commission). 2012. The European Bioeconomy in 2030: Delivering Sustainable Growth by Addressing the Grand Societal Challenges. 6 Formas (Swedish Research Council for Environment, Agricultural Sciences and Spatial Planning). 2012. Swedish Research and Innovation Strategy for a Bio-based Economy. 7 OSTP (Office of Science and Technology Policy). 2012. National Bioeconomy Blueprint. Washington, DC: The White House. 8 OECD (Organisation for Economic Co-operation and Development). 2015. Building a Bioeconomy: How Nations Approach Capacity Building in Industrial Biotechnology. Paris: OECD. 9 OSTP (Office of Science and Technology Policy). 2012. National Bioeconomy Blueprint. Washington, DC: The White House.



Private-Sector Investment and Diversification of Sources of Capital Increasingly, capital for biotechnology research is not limited to governmental sources and private-sector funding. Crowdsourcing websites like Indiegogo and Kickstarter have been a source of funding for entrepreneurs and small companies for biotechnology products since they launched in 2008 and 2009, respectively. Changes in 2016 to the U.S. Securities and Exchange Commission codes affecting crowdfunding have given rise to a number of equity sites, such as WeFunder.org, which provide another option for biotech startups and entrepreneurs. Accelerator organizations like Y Combinator and IndieBio also have provided seed money for biotechnology-product developers. The diversification of capital sources has played a role in the diversification of biotechnology-product developers. Societal Drivers In addition to technical and economic drivers, there are a large variety of societal drivers that come into play in the context of both current and future products of biotechnology. The extent to which these societal drivers are directly part of the regulatory system depends on the specifics of the agency and the authority, but they often set the stage for the discussion regarding the evaluation, oversight, and usage of a specific biotechnology product or class of products. Climate Change & Food Security: Some biotechnology products are envisaged as tools to help address food security and climate change and to promote “green growth” and environmental sustainability. For example, a U.S. government study predicts that new biotechnology products associated with biomass production could cut U.S. greenhouse gas emissions by 400 million tons per year, or 8 percent. Biotechnology products that are successful at addressing societal challenges may have associated economic benefits such as increased productivity and new job creation (including jobs for higher skilled labor)10. Non-Traditional Players: Once the purview of PhD-level researchers, biotechnology is taught in some high school science classes, and, since 2009, a growing number of DIYbio community laboratories in the United States and Europe teach basic biotechnology to nonexperts through formal classes and informal education approaches. In 2013, a survey of the DIYbio community, estimated to be between 3,000 and 4,000 people worldwide, found that the majority of the 359 respondents (82 percent) were in the United States, 10 percent were in Europe, 4 percent in Canada, 1 percent in China, and 2 percent from elsewhere. The community respondents were mostly adult males (75 percent), and few of them (less than 10 percent) work solitarily, that is, outside of community laboratory spaces where technical expertise and equipment are concentrated11.

Major Markets • Government grants and payments • Resource industries • Exports • Agriculture and food sectors • Other

10 Biomass R&D Board. 2016. Federal Activities Report on the Bioeconomy. 11 Grushkin, D., T. Kuiken, and P. Millet. 2014. Seven Myths & Realities about Do-It-Yourself Biology. Washington, DC: Woodrow Wilson Center for International Scholars.



Supply Chain Key Buying Industries • Agriculture, Forestry, Fishing and Hunting in the US • Animal Food Production in the US • Petroleum Refining in the US • Fertilizer Manufacturing in the US • Brand Name Pharmaceutical Manufacturing in the US • Generic Pharmaceutical Manufacturing in the US • Veterinary Services in the US • Diagnostic & Medical Laboratories in the US Key Selling Industries • Inorganic Chemical Manufacturing in the US • Organic Chemical Manufacturing in the US • Plastic Pipe & Parts Manufacturing in the US • Hose & Belt Manufacturing in the US • Glass Product Manufacturing in the US • Electrical Equipment Manufacturing in the US • Medical Instrument & Supply Manufacturing in the US • Glasses & Contact Lens Manufacturing in the US



Competitive Landscape

Market Share Concentration The companies holding the largest market share in the Biotechnology in the US industry include Genentech Inc., AbbVie Inc., Amgen Inc., Gilead Sciences Inc. and Bayer AG.

Geographical Concentration The life science industry has localized into clusters, due to the localization of small and large life science companies, academic institutions that conduct biomedical and scientific research, sources of funding for early stage companies, and support from local, state and federal governments. While there are life science clusters all over the United States, Greater Boston and the Bay Area (California) are considered the top two life science clusters in the country, and are considered life science hubs due to the large-scale localization of companies, research institutions, funding and government support12.

Barriers to Entry A few key strategic elements are critical to the early-stage biotechnology company’s growth and success. Early-stage company often can be a business case study for high attrition rates among product candidates, huge technical risk, and very long product-development time lines of 8 to 12 years.13 The purpose of the U.S. regulatory system is to “protect public health, welfare, safety, and our environment while promoting economic growth, innovation, competitiveness, and job creation”14. To strike this balance, risk in the U.S. system has been understood to pertain to consumer safety and environmental protection; however, the term can be defined more broadly (if informally) as the ‘Coordinated Framework for Biotech’. Statutes and Protection Goals Related to the U.S. Environmental Protection Agency (EPA), the U.S. Food and Drug Administration (FDA), and the U.S. Department of Agriculture (USDA) for the Regulation of Biotechnology Products

Agency Statute Protection Goal

EPA Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA)

Prevent and eliminate unreasonable adverse effects on the environment

For environmental and occupational risks, this involves comparing economic, social, and environmental risks to human health and the environment and benefits associated with the pesticide use.

For dietary or residential human health effects, the sole standard is the “safety” of all the combined exposures to the pesticide and related compounds.

12 http://nrs.harvard.edu/urn-3:HUL.InstRepos:37945132. Retrieved 2nd December 2019 13 Morton, F. & Boller, L (2017). Barriers to Competition in the US pharmaceutical industry 14 EOP (Executive Office of the President). Federal Register. Vol. 76. 2011. Executive Order 13563 of January 18, 2011: Improving Regulation and Regulatory Review; pp. 3821–3823.



Agency Statute Protection Goal

EPA Federal Food, Drug, and Cosmetic Act (FDCA)

Ensure that no harm will result from aggregate exposure to the pesticide chemical residue, including all anticipated dietary exposures and all other exposures for which there is reliable information.

EPA Toxic Substances Control Act (TSCA)

Prevent the manufacture, processing, distribution in commerce, use, or disposal of chemical substances, or any combination of such activities with such substances, from presenting an unreasonable risk of injury to health or the environment, including an unreasonable risk to a potentially exposed or susceptible population, without consideration of costs or other nonrisk factors.

FDA FDCA Ensure human and animal food is safe, sanitary, and properly labeled. Ensure human and animal drugs are safe and effective. Ensure the reasonable assurance of the safety and effectiveness of devices intended for human use. Ensure cosmetics are safe and properly labeled.

FDA Public Health Service Act

Ensure the safety, purity, and potency of biological products.

USDA Animal Health Protection Act (AHPA)

Protect livestock from animal pest and disease risks.

USDA Plant Protection Act (PPA)

Protect agricultural plants and agriculturally important natural resources from damage caused by organisms that pose plant pest or noxious weed risks.

USDA Federal Meat Inspection Act

Ensure that the United States’ commercial supply of meat, poultry, and egg products is safe, wholesome, and correctly labeled.

USDA Poultry Products Inspection Act

Ensure that the United States’ commercial supply of meat, poultry, and egg products is safe, wholesome, and correctly labeled.

USDA Egg Products Inspection Act

USDA Virus-Serum-Toxin Act

Ensure that veterinary biologics are pure, safe, potent, and effective.

Consumer and Occupational Safety Diverse, new types of biotechnology products entering the market may pose new consumer- and occupational-safety challenges. The important questions for a specific product are as follows: • Does any federal regulatory agency have jurisdiction to regulate it and, if so, which agency (or agencies)?

• Do the regulatory agencies have adequate tools to analyze the types of risk the product may present? Multiple federal agencies are responsible for consumer and occupational safety. Under the Food, Drug, and Cosmetic Act (FDCA), FDA is a major product safety regulator. EPA is mandated to ensure safety of chemicals across a number of uses, including consumer products, occupational exposures, and manufacturing. Under the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA)15 and Section 408 of the FDCA, EPA regulates consumer safety with respect to pesticides and pesticide residues in food and occupational safety with respect to uses of pesticides in the workplace. The USDA also plays a crucial role in consumer safety with respect to various food products, such as meat and poultry.

15 U.S.C. § 136 et seq.



In addition to EPA, FDA, and USDA, the Consumer Product Safety Commission (CPSC) has residual jurisdiction to regulate consumer products not regulated by the other agencies, so biotechnology products that are not regulated by one or more of the statutes listed in Table 3-1 may fall under CPSC’s jurisdiction. Under FIFRA, EPA is completely responsible for all pesticide risks, including in the workplace. Under TSCA, EPA and OSHA share responsibility for chemical safety in the workplace; EPA evaluates and manages the chemical risk, and OSHA establishes and enforces workplace exposure limits and safety practices. In coming years, OSHA may confront novel issues in workplaces where biotechnology is used as a means of production in diverse industrial, commercial, and agricultural settings. Agencies concerned about consumer and occupational safety have to be attuned to assessing not just the types of new products but also the characteristics of the anticipated users because the safety of some future biotechnology products depends on the skill and intent of the user along with the product design. Additional agencies may need to become involved when specific biotechnology products fall within their jurisdiction—for example, the National Highway Traffic Safety Administration (NHTSA) may be called upon to address safety issues related to future biotechnology-based car batteries. This section does not attempt to identify every agency, such as NHTSA, that may occasionally encounter new biotechnology products and instead focuses on agencies—FDA, CPSC, OSHA, EPA, and finally USDA—with broad jurisdiction over consumer and occupational safety.

Industry SWOT Analysis The trade-weighted index (TWI) is used to measure the value of the US dollar against other major currencies. As the value of the dollar increases, US goods, including biotechnology products, become relatively more expensive in foreign markets, while imports become relatively less expensive to US consumers. As the TWI increases, demand for industry goods decreases. The TWI is expected to increase in 2019, posing a potential threat to the industry16. Biotechnology is one of the most-active fields of research and development (R&D). Investment in R&D promotes new drugs and vaccines, disease-resistant crops, enzymatic manufacturing processes and methods of dealing with hazardous materials. Furthermore, increased R&D expenditure encourages new industry product development, which in turn boosts revenue. R&D expenditure is expected to increase in 2020, representing a potential opportunity for the industry.

Reasons why BioTech Companies May Fail17 Flawed financial strategy Finance is always a challenge for any young startup. The challenge is even greater for biotech startups, which need to raise significantly more money and make sure it lasts long enough. Inexperienced management The management of a company can be instrumental to the success or failure of a biotech startup. “For newer entrepreneurs and their companies, a key to success is to network and seek out guidance from experienced mentors and area specialists — drug development is very much still an art form and their insights could really make a big difference to your company’s chances of success,” says Davidson Ateh, CEO of the oncology biotech company BioMoti. Mediocre science To succeed, a biotech company needs strong data to convince investors, partners, and eventually regulators that a certain product or technology is worth it. Before committing to a project it’s important to ensure that there is a market need and the approach is innovative and superior to that of competitors.

16 "Biotechnology Industry in the US". IBIS. July 2019. 17 https://www.labiotech.eu/tops/biotech-startups-failure-advice/. Retrieved 2nd December 2019



Competition Competition can also be intimidating and a barrier to success. “Don’t succumb to easy dismissal of your competitors. From bitter experience, competition is far more intense than you ever appreciate when you’re in one of these companies,” advises Kevin Johnson, co-founder and Partner at the British life sciences investor Medicxi. Poor timing Although the development of biotechnology products takes considerable time, making swift decisions at the right time can be critical for the success of a biotech startup. One of the most difficult to make can be whether to kill a particular product or technology that is not performing as expected. One might be tempted to keep going and gather more data, but that’s often a mistake. Not taking risks While there should be a plan carefully laid out, biotech is a very unpredictable business. A company needs to be ready to take calculated risks in order to survive difficult times.



Financing of BioTech Firms

Fund-Raising Over Time The following graph looks at fund-raising activities of 8,933 BioTech companies in terms of dollar value since 1997. Number of Funding Rounds: 15,221 Total Funding Amount: $196.2B

Where are funds being sourced?



Investors Number of Lead Investors: 4,751 Number of Investors: 14,769

Top 500 investors into US BioTech

.406 Ventures USA Venture Capital

180 Degree Capital USA Venture Capital

3i Group UK Private Equity Firm

500 Startups USA Accelerator, Venture Capital

5AM Ventures USA Venture Capital

8VC USA Venture Capital

Abingworth UK Venture Capital

Abstract Ventures USA Venture Capital

Accel USA Venture Capital

Acceleprise USA Accelerator

Acequia Capital (Acecap) USA Micro VC

Adams Street Partners USA Private Equity Firm

Advanced Technology Ventures USA Venture Capital

Advantage Capital USA Private Equity Firm, Venture Capital

Advent International USA Private Equity Firm

Advent Venture Partners UK Venture Capital

Agility Capital USA Venture Debt

Aisling Capital USA Private Equity Firm

Albion Capital Group UK Venture Capital

Alchemist Accelerator USA Accelerator

Allen & Company LLC USA Family Investment Office, Investment Bank, Venture Capital

Alliance of Angels USA Angel Group

Alloy Ventures USA Venture Capital



Alta Partners USA Venture Capital

Altos Ventures USA Venture Capital

Alumni Ventures Group USA Venture Capital

Amadeus Capital Partners UK Venture Capital

Amazon Alexa Fund USA Corporate Venture Capital

AME Cloud Ventures USA Venture Capital

Amplify Partners USA Venture Capital

Andera Partners France Private Equity Firm, Venture Capital

Andreessen Horowitz USA Venture Capital

Angel CoFund UK Angel Group, Government Office

Ann Arbor SPARK USA Accelerator

Apax Partners UK Private Equity Firm

ARCH Venture Partners USA Venture Capital

Artiman Ventures USA Venture Capital

Aspect Ventures USA Venture Capital

Asset Management Ventures (AMV) USA Venture Capital

ATDC USA Incubator, University Program

Atlas Venture USA Venture Capital

Auriga Partners France Venture Capital

Austin Ventures USA Venture Capital

Avalon Ventures USA Venture Capital

Bain Capital USA Private Equity Firm

Bain Capital Ventures USA Corporate Venture Capital

Baird Capital USA Venture Capital

BAM Ventures USA Micro VC, Venture Capital

Band of Angels USA Angel Group

Base Ventures USA Micro VC, Venture Capital

Battery Ventures USA Venture Capital

Bay City Capital USA Venture Capital

Bay Partners USA Venture Capital

Bayern Kapital Germany Government Office, Venture Capital

BDC Venture Capital Canada Government Office, Venture Capital Ben Franklin Technology Partners of Northeastern Pennsylvania USA Government Office Ben Franklin Technology Partners of Southeastern Pennsylvania USA Government Office

Benchmark USA Venture Capital

Beringea UK Private Equity Firm, Venture Capital

Berkeley SkyDeck USA Accelerator

Bessemer Venture Partners USA Venture Capital

Bill & Melinda Gates Foundation USA Family Investment Office

BioAdvance USA Venture Capital

Birchmere Ventures USA Venture Capital

Blackstone Group USA Private Equity Firm



Blumberg Capital USA Venture Capital

bmp Ventures Germany Venture Capital

BNP Paribas Private Equity France Private Equity Firm

Bon Angels Venture Partners South Korea Venture Capital

BoomStartup USA Accelerator

Boomtown Accelerators USA Accelerator

Boost VC USA Accelerator

Boston Millennia Partners USA Private Equity Firm

Boulder Ventures USA Venture Capital

Bpifrance France Government Office, Investment Bank

Braemar Energy Ventures USA Venture Capital

Brainchild Holdings USA Micro VC, Venture Capital

btov Partners Switzerland Venture Capital

Burrill & Company USA Private Equity Firm

Business Development Bank of Canada Canada Government Office, Venture Capital

Cambridge Angels group UK Angel Group

Canaan Partners USA Venture Capital

Capital Factory USA Accelerator, Co-Working Space, Incubator, Venture Capital

Capstone Partners Co., Ltd. South Korea Micro VC

CincyTech USA Government Office, Micro VC

CIT GAP Funds USA Venture Capital

Clarus Ventures USA Venture Capital

Clearstone Venture Partners USA Venture Capital

CMEA Capital USA Venture Capital

Coatue Management USA Hedge Fund

Collaborative Fund USA Micro VC

Commonwealth Capital Ventures USA Private Equity Firm, Venture Capital

ComVentures USA Venture Capital

Connecticut Innovations USA Government Office

Core Capital Partners USA Venture Capital

Correlation Ventures USA Venture Capital

CRCM Ventures USA Venture Capital

Creative Destruction Lab Canada Accelerator, Angel Group, Entrepreneurship Program, Incubator, University Program

Credit Suisse Switzerland Investment Bank

Crosslink Capital USA Venture Capital

Crowdcube UK —

CRV USA Venture Capital

Cultivation Capital USA Venture Capital

CVP Management USA Micro VC, Venture Capital

DAG Ventures USA Venture Capital

Daniel Curran USA Individual/Angel

Data Collective DCVC USA Venture Capital



DCM Ventures USA Private Equity Firm, Venture Capital

Dell Technologies Capital USA Corporate Venture Capital

Delphi Ventures USA Venture Capital

DeNovo Ventures USA Venture Capital

Deutsche Bank Germany Investment Bank

DFJ USA Venture Capital

DHVC USA Venture Capital

Digital Garage Japan —

Dingman Center for Entrepreneurship USA Angel Group

DN Capital USA Venture Capital

DNX Ventures USA Venture Capital

Domain Associates USA Venture Capital

Dorm Room Fund USA Micro VC, University Program

Downing Ventures UK Venture Capital

Draper Associates USA Venture Capital

Dreamit Ventures USA Accelerator, Venture Capital

Earlybird Venture Capital Germany Venture Capital

EASME - EU Executive Agency for SMEs Belgium Government Office

EDBI Singapore Venture Capital

Edison Partners USA Venture Capital

Eight Roads Ventures UK Venture Capital

Empower Investment China Venture Capital

Enterprise Ireland Ireland Government Office

Enterprise Partners USA Micro VC, Venture Capital

EPIC Ventures USA Venture Capital

Esther Dyson USA Investment Partner, Individual/Angel

European Investment Bank (EIB) Luxembourg Government Office, Investment Bank

EvoNexus USA Incubator

Expansion Venture Capital USA Micro VC, Venture Capital

Fabrice Grinda USA Investment Partner, Individual/Angel

Felicis Ventures USA Venture Capital

ff Venture Capital USA Venture Capital

Fidelity USA Investment Bank

Fidelity Management and Research Company USA Private Equity Firm

Fidelity Ventures USA Venture Capital

First Round Capital USA Venture Capital

FirstMark USA Venture Capital

FJ Labs USA Micro VC, Venture Capital

Flagship Pioneering USA Venture Capital

Floodgate USA Micro VC, Venture Capital Florida Institute for the Commercialization of Public Research USA Micro VC

Flybridge Capital Partners USA Venture Capital

Fonds de solidarité FTQ Canada Venture Capital



FOOD-X USA Accelerator

Forbion Capital Partners The Netherlands Venture Capital

Formation 8 USA Venture Capital

Foundation Capital USA Venture Capital

Founder Collective USA Micro VC

Founder Friendly Labs USA Accelerator

Founders' Co-op USA Venture Capital

Founders Fund USA Venture Capital

F-Prime Capital USA Venture Capital

Frazier Healthcare Partners USA Private Equity Firm

Freestyle Capital USA Micro VC, Venture Capital

Frontier Venture Capital USA Venture Capital

FundersClub USA Micro VC

GE Capital Canada Corporate Venture Capital

GE Equity USA Venture Capital

GE Ventures USA Corporate Venture Capital

Gemini Israel Ventures Israel Venture Capital

gener8tor USA Accelerator

General Atlantic USA Private Equity Firm

General Catalyst USA Venture Capital

General Motors Ventures USA Corporate Venture Capital

GGV Capital USA Venture Capital

GIC Singapore Private Equity Firm

Gimv Belgium Private Equity Firm, Venture Capital

Giza Venture Capital Israel Venture Capital

Global Brain Corporation Japan Venture Capital

Goldman Sachs USA Investment Bank, Venture Capital

Google USA —

Grand Central Tech USA Accelerator

Granite Ventures USA Venture Capital

Great Oaks Venture Capital USA Micro VC

Green D Ventures USA Venture Capital

Greenspring Associates USA Fund Of Funds, Venture Capital

Greycroft USA Venture Capital

Greylock Partners USA Venture Capital

GrowthWorks Capital Canada Venture Capital

GV USA Corporate Venture Capital, Venture Capital

H.I.G. Capital USA Private Equity Firm

Hasso Plattner Ventures Germany Venture Capital

HAX China Accelerator

HBM Healthcare Investments AG Switzerland Venture Capital

Healthbox USA Accelerator

HealthCap Sweden Venture Capital



HealthCare Ventures USA Venture Capital

Hedgewood Canada Family Investment Office

Hercules Capital, Inc. USA Venture Debt

Highland Capital Partners USA Venture Capital

High-Tech Grunderfonds Germany Venture Capital

Hillhouse Capital Group China Private Equity Firm

HLM Venture Partners USA Venture Capital

Homebrew USA Venture Capital

Horizons Ventures Hong Kong Venture Capital

Houston Angel Network USA Angel Group

Hyde Park Angels (HPA) USA Venture Capital

IA Ventures USA Venture Capital

Icon Ventures USA Venture Capital

ICONIQ Capital USA Family Investment Office, Private Equity Firm, Venture Capital

IDG Capital China Private Equity Firm

IDG Ventures India Corporate Venture Capital

Idinvest Partners France Private Equity Firm

Ignition Partners USA Venture Capital

Imperial Innovations UK University Program

Index Ventures USA Venture Capital

IndieBio USA Accelerator

Industrifonden Sweden Venture Capital

Industry Ventures USA Venture Capital

Initialized Capital USA Venture Capital

Innova Memphis USA Venture Capital

Innovate UK UK Entrepreneurship Program, Venture Capital

Innovation Endeavors USA Venture Capital

Innovation Works USA Government Office, Incubator

Inovia Capital Canada Venture Capital

In-Q-Tel USA Government Office

Integral Capital Partners USA Venture Capital

Intel Capital USA Corporate Venture Capital, Venture Capital

International Finance Corporation USA Government Office, Private Equity Firm, Venture Capital

Intersouth Partners USA Venture Capital

InterWest Partners USA Venture Capital

investiere | Verve Capital Partners Switzerland Micro VC

Investor Growth Capital Limited Sweden Venture Capital

Invus USA Venture Capital

IP Group Plc UK Venture Capital

IVP (Institutional Venture Partners) USA Venture Capital

J. Hunt Holdings USA Family Investment Office

JAFCO Asia Singapore Venture Capital



JAFCO Japan Japan Incubator, Private Equity Firm, Venture Capital

Javelin Venture Partners USA Venture Capital

Johnson & Johnson Development Corporation USA Corporate Venture Capital, Venture Capital

JP Morgan Chase USA Investment Bank

JPMorgan Partners (JPMP) USA Investment Bank

Jump Capital USA Venture Capital

JumpStart Inc. USA Accelerator, Venture Capital

Keiretsu Forum USA Angel Group, Venture Capital

Keiretsu Forum Northwest USA Angel Group

Kevin Moore USA Individual/Angel

Khosla Ventures USA Venture Capital

Kickstart Seed Fund USA Micro VC, Venture Capital

Kima Ventures France Micro VC

Kleiner Perkins USA Venture Capital

Kodiak Venture Partners USA Venture Capital

Kohlberg Kravis Roberts USA Private Equity Firm

Korea Investment Partners South Korea Private Equity Firm, Venture Capital

LAUNCH USA Accelerator, Venture Capital

LaunchCapital USA Micro VC

Legend Capital China Venture Capital

Lehman Brothers USA Investment Bank

Lerer Hippeau USA Micro VC, Venture Capital

Life Sciences Partners The Netherlands Private Equity Firm

Lifeline Ventures Finland Micro VC, Venture Capital

Lightbank USA Venture Capital

Lighter Capital USA Venture Debt

Lightspeed Venture Partners USA Venture Capital

Liquid 2 Ventures USA Micro VC, Venture Capital

LocalGlobe UK Venture Capital

Louis Beryl USA Individual/Angel

Ludlow Ventures USA Micro VC, Venture Capital

Lux Capital USA Venture Capital

M12 USA Corporate Venture Capital, Venture Capital

Madrona Venture Group USA Venture Capital

Maine Angels USA Angel Group

Marc Bell Ventures USA Private Equity Firm, Venture Capital

Marc Benioff USA Individual/Angel

Mark Cuban USA Investment Partner, Individual/Angel

Marker USA Venture Capital

MaRS Investment Accelerator Fund Canada Venture Capital

MassChallenge USA Accelerator

Matrix Partners USA Venture Capital

Matrix Partners China China Fund Of Funds, Venture Capital



Maven Capital Partners UK Private Equity Firm

Maverick Ventures USA Venture Capital

Maveron USA Venture Capital

Mayfield Fund USA Venture Capital

MB Venture Partners USA Micro VC, Venture Capital

MedTech Innovator USA Accelerator

Menlo Ventures USA Venture Capital

Mercury Fund USA Venture Capital

Meritech Capital Partners USA Venture Capital

Microsoft USA —

Microsoft Accelerator Beijing China Accelerator

MIT delta v USA Accelerator, University Program

MIT Media Lab USA —

Mitsubishi UFJ Capital Japan Venture Capital

Mitsui & Co Japan —

Mitsui Global Investment USA Corporate Venture Capital

Mobius Venture Capital USA Venture Capital

Mohr Davidow Ventures USA Venture Capital

Morado Ventures USA Micro VC

Morgan Stanley USA Investment Bank

Morgenthaler Ventures USA Venture Capital

Morningside Group China Venture Capital

Morningside Venture Capital China Venture Capital

Motorola Solutions Venture Capital USA Corporate Venture Capital

MPM Capital USA Venture Capital

National Institutes of Health USA Entrepreneurship Program

National Science Foundation USA Entrepreneurship Program, Government Office

Naval Ravikant USA Investment Partner, Individual/Angel

NDRC Ireland Micro VC

New Enterprise Associates USA Venture Capital

New Leaf Venture Partners USA Venture Capital

New York Angels USA Angel Group

NewSpring USA Private Equity Firm

Next47 USA Venture Capital

NFX USA Venture Capital

Noro-Moseley Partners USA Venture Capital

North Bridge Venture Partners & Growth Equity USA Venture Capital

Northern Light Venture Capital China Venture Capital

Northgate Capital USA Private Equity Firm

Norwest Equity Partners (NEP) USA Private Equity Firm

Norwest Venture Partners USA Venture Capital

Novak Biddle Venture Partners USA Venture Capital

Novartis Venture Fund Switzerland Corporate Venture Capital, Venture Capital



Novo Holdings Denmark Venture Capital

NYSERDA USA Government Office

Oak Investment Partners USA Private Equity Firm, Venture Capital

OCA Ventures USA Venture Capital

Omidyar Network USA Family Investment Office

Omnes Capital France Venture Capital

ONSET Ventures USA Venture Capital

OrbiMed USA Private Equity Firm

Oreilly AlphaTech Ventures USA Venture Capital

OUP (Osage University Partners) USA University Program, Venture Capital

OVP Venture Partners USA Venture Capital

Oxford Bioscience Partners USA Venture Capital

Oxford Finance LLC USA Private Equity Firm

Oxford Technology Management UK Micro VC, Venture Capital

Paladin Capital Group USA Private Equity Firm, Venture Capital

Parkwalk Advisors UK Venture Capital

Pathfinder USA Angel Group

Paul Buchheit USA Investment Partner, Individual/Angel

Pear Ventures USA Venture Capital

Pegasus Tech Ventures USA Venture Capital

Pelion Venture Partners USA Venture Capital

Pequot Capital USA Government Office, Venture Capital

Perceptive Advisors USA Hedge Fund

Pfizer Venture Investments USA Corporate Venture Capital

Pitango Venture Capital Israel Venture Capital

Plug and Play USA Accelerator

Polaris Partners USA Venture Capital

Portland Seed Fund USA Micro VC

Primary Venture Partners USA Venture Capital

Prism Venture Management USA Venture Capital

Pritzker Group Venture Capital USA Venture Capital

Qiming Venture Partners China Venture Capital

Quake Capital Partners USA Accelerator, Venture Capital

Qualcomm USA —

Qualcomm Ventures USA Corporate Venture Capital

QueensBridge Venture Partners USA Micro VC

RA Capital Management USA Venture Capital

Real Ventures Canada Micro VC, Venture Capital

RebelBio UK Accelerator

Relay Ventures Canada Venture Capital

Rev1 Ventures USA Venture Capital

Revolution USA Venture Capital

Rho Capital Partners USA Private Equity Firm, Venture Capital



Rho Ventures USA Private Equity Firm, Venture Capital

Right Side Capital Management USA Micro VC

River Cities Capital Funds USA Venture Capital

Robert Bosch Venture Capital Germany Corporate Venture Capital

Roche Venture Fund Switzerland Corporate Venture Capital

Rock Health USA Micro VC

RockPort Capital USA Venture Capital

RRE Ventures USA Venture Capital

Runa Capital USA Venture Capital

RUSNANO USA Venture Capital

Rustic Canyon Partners USA Venture Capital

Safeguard Scientifics USA Private Equity Firm

SAIF Partners Hong Kong Private Equity Firm

Samsung NEXT USA Venture Capital

Samsung Ventures South Korea Corporate Venture Capital

Sand Hill Angels USA Angel Group

Sanderling Ventures USA Venture Capital

SBI Investment Japan Venture Capital

SBRI Healthcare UK Government Office

Scale Venture Partners USA Venture Capital

Scottish Equity Partners UK Private Equity Firm, Venture Capital

SeedInvest USA Micro VC

Sequoia Capital USA Venture Capital

Sequoia Capital China China Venture Capital

Sequoia Capital India India Venture Capital

Sequoia Capital Israel Israel Venture Capital

Serra Ventures USA Venture Capital

Seventure Partners France Venture Capital

Sevin Rosen Funds USA Venture Capital

SGH CAPITAL Luxembourg Private Equity Firm

Shasta Ventures USA Venture Capital

Sherpa Capital USA Venture Capital

Sierra Ventures USA Venture Capital

SIG China (SIG Asia Investments) China Venture Capital

Sigma Partners USA Venture Capital

Signatures Capital USA Venture Capital

Silicon Valley Bank USA Investment Bank

Sinovation Ventures China Venture Capital

Siparex Groupe France Private Equity Firm

Slow Ventures USA Micro VC

SMBC Venture Capital Japan Investment Bank, Venture Capital

Social Capital USA Venture Capital

Social Starts USA Micro VC



Sofinnova Investments USA Venture Capital

Sofinnova Partners France Venture Capital

SoftBank Japan Investment Bank

SoftBank Capital Japan Corporate Venture Capital

Softbank Ventures Asia South Korea Venture Capital

SoftBank Vision Fund UK Venture Capital

Soma Capital USA Micro VC, Venture Capital

SOSV USA Accelerator, Venture Capital

Spark Capital USA Venture Capital

SparkLabs Accelerator South Korea Accelerator

Split Rock Partners USA Venture Capital

Sprout Group USA Venture Capital

Square 1 Bank USA Venture Debt

SR One USA Corporate Venture Capital

St. Paul Venture Capital USA Private Equity Firm, Venture Capital

StartEngine USA —

Start-Up Chile Chile Accelerator

Startup Funding Club UK Micro VC

StartUp Health USA Venture Capital

StartX (Stanford-StartX Fund) USA Accelerator

Starve Ups USA Accelerator

Streamlined Ventures USA Venture Capital

Summit Partners USA Private Equity Firm

Susa Ventures USA Micro VC, Venture Capital

Sutter Hill Ventures USA Venture Capital

SV Angel USA Micro VC

SV Health Investors USA Venture Capital

T. Rowe Price USA Private Equity Firm

TA Associates USA Private Equity Firm

Tech Coast Angels USA Angel Group

Techstars USA Accelerator

Techstars Boston Accelerator USA Accelerator

Techstars New York City Accelerator USA Accelerator

Techstars Seattle Accelerator USA Accelerator

TEDCO USA Government Office, Venture Capital

TeleSoft Partners USA Venture Capital

Temasek Holdings Singapore Private Equity Firm

Tencent Holdings China —

Texas Venture Labs USA Accelerator

The Carlyle Group USA Private Equity Firm

The FSE Group UK Venture Capital

Third Rock Ventures USA Venture Capital

Three Arch Partners USA Venture Capital



Threshold USA Venture Capital

Thrive Capital USA Venture Capital

Tiger Global Management USA Hedge Fund

TL Ventures USA Venture Capital

Total Access Fund USA Venture Capital

TPG USA Private Equity Firm

TPG Growth USA Private Equity Firm

Trinity Ventures USA Venture Capital

True Ventures USA Venture Capital

TSVC USA Venture Capital

Tuesday Capital USA Venture Capital

TVM Capital Germany Private Equity Firm

Two Sigma Ventures USA Venture Capital

U.S. Venture Partners (USVP) USA Venture Capital

Ulu Ventures USA Micro VC, Venture Capital

Uncork Capital USA Micro VC

Unilever Ventures UK Corporate Venture Capital, Venture Capital

Upfront Ventures USA Venture Capital

UpHonest Capital USA Micro VC, Venture Capital

US Department of Energy USA Government Office

VA Angels Canada Angel Group

Valhalla Partners USA Venture Capital

VantagePoint Capital Partners USA Venture Capital

Velocity Canada Incubator, University Program

Venrock USA Venture Capital

Ventech France Venture Capital

Venture Investors USA Venture Capital

Venture Kick Switzerland Incubator

VentureSouth USA Angel Group

Versant Ventures USA Venture Capital

Vertex Ventures USA Venture Capital

VF Venture Denmark Government Office, Venture Capital

VilCap Investments USA Micro VC

Village Ventures USA Venture Capital

Vivo Capital USA Venture Capital

Vulcan Capital USA Family Investment Office, Private Equity Firm, Venture Capital

Walden International USA Venture Capital

Warburg Pincus USA Private Equity Firm

Wavemaker Partners Singapore Venture Capital

Webb Investment Network USA Family Investment Office

Wei Guo USA Investment Partner, Individual/Angel

Wellcome Trust UK Government Office, Venture Capital

Wellington Management USA Investment Bank, Venture Capital



Wellington Partners Germany Venture Capital

Western Technology Investment USA Venture Capital

WI Harper Group USA Venture Capital

Wisconsin Investment Partners USA Angel Group

Y Combinator USA Accelerator

ZhenFund China Venture Capital

Zillionize Angel USA Angel Group



Major Players

Early Stage BioTech Companies Number of Organizations: 802 Funding Status: Early Stage Venture Number of Founders: 1,277 Average Founded Date: Dec 16, 2010 Number of For-Profit Companies: 478 Top Funding Types: Series A, Series B, Debt Financing, Grant, Convertible Note Top 50 Early-State BioTech Companies

Company Sectors Location Description Website Revenue

Founded

EGenesis Biopharma, Biotechnology, Genetics, Life Science, Medical

Cambridge, Massachusetts, United States

EGenesis designs xenotransplantation for the benefit of human health.

www.egenesisbio.com/

$10M to $50M 2014

Bigfinite

Big Data, Biotechnology, Information Services, Information Technology, Internet of Things, Pharmaceutical, SaaS

San Francisco, California, United States

Bigfinite is a cloud-based SaaS platform that helps optimize industrial processes in biotech and pharma. www.bigfinite.com/

$1M to $10M 2013

Insilico Medicine

Artificial Intelligence, Biotechnology, Genetics, Pharmaceutical

Rockville, Maryland, United States

Insilico Medicine is dedicated to develop high-performance AI platform for drug development to treat cancer and age-related diseases www.insilico.com/ 2014

Freenome Biotechnology, Health Care, Health Diagnostics, Personal Health

South San Francisco, California, United States

Freenome is a platform that helps design healthy conditions for an individual based on his/her cell-free genome www.freenome.com 2014



Geltor Advanced Materials, Biotechnology

San Leandro, California, United States

The bio-design company that makes the world’s most advanced proteins for consumers, with a focus on unique functionality and sustainability. www.geltor.com/

$1M to $10M 2015

Perfect Day Biotechnology, Food Processing Berkeley, California, United States

Perfect Day Feeding a growing world with sustainable, healthy, humane milk.

www.perfectdayfoods.com/

$1M to $10M

May 1, 2014

PierianDx Biotechnology, Health Diagnostics, Medical, SaaS

St Louis, Missouri, United States

PierianDx is catalyzing global adoption of genomic sequencing in healthcare www.pieriandx.com/

$1M to $10M 2014

Helix

Big Data, Biotechnology, Genetics, Health Care, Personal Health, Wellness

San Carlos, California, United States

Helix is a health company that focuses on personal genomics and connects people with insights into their own DNA. www.helix.com/ —

Jul 15, 2015

Insitro Biotechnology, Life Science, Machine Learning, Pharmaceutical


Insitro is revolutionizing pharmaceutical R&D by leveraging machine learning for drug discovery. www.insitro.com/ 2018

Mile High Labs

Biotechnology, Consumer Goods, Manufacturing, Retail

Boulder, Colorado, United States

Mile High Labs is an end-to-end GMP certified manufacturer of premium CBD crude oil, distillate, and isolate. www.milehighlabs.com/ 2016

BlackThorn Therapeutics

Biopharma, Biotechnology, Health Care, Therapeutics


BlackThorn Therapeutics is pioneering next-generation AI technologies to advance targeted therapeutics for neurobehavioral health.

www.blackthornrx.com/

$1M to $10M 2015



Mindstrong Biopharma, Biotechnology, Health Care

Palo Alto, California, United States

Mindstrong Health is transforming the diagnosis and treatment of behavioral health disorders through the ubiquity of mobile technology mindstrong.com/

$1M to $10M 2014

Imagen Technologies

Artificial Intelligence, Biotechnology, Health Care, Health Diagnostics, Hospital, Information Technology, Robotics

New York, New York, United States

Imagine a world where all patients are diagnosed instantly by leading experts. www.imagen.ai

Less than $1M

Jan 1, 2016

A2 Biotherapeutics Biotechnology, Life Science

Westlake Village, California, United States

A2 Biotherapeutics develops novel medicines for serious illness. www.a2biotherapeutics.com 2018

Azeria Therapeutics Biotechnology, Therapeutics


Azeria Therapeutics is the world’s first pioneer factor drug discovery company. www.azeriatherapeutics.com 2017

CODA Biotherapeutics Biotechnology, Therapeutics


CODA Biotherapeutics is a preclinical-stage biopharmaceutical company.

www.codabiotherapeutics.com/ 2014

T3D Therapeutics Biotechnology, Medical, Therapeutics

Durham, North Carolina, United States

T3D Therapeutics is a company developing remedial therapeutics for Alzheimer’s disease and other CNS disorders. t3dtherapeutics.com 2013

Motif FoodWorks Biotechnology, Food and Beverage

Boston, Massachusetts, United States

Motif makes ingredients for the next generation of plant-based and healthy foods. madewithmotif.com/ 2019

ArsenalBio

Biotechnology, Cloud Computing, Machine Learning, Software


ArsenalBio is a programmable cell therapy company www.arsenalbio.com/

Kronos Bio Biotechnology, Chemical, Therapeutics


Kronos Bio is dedicated to the research and development www.kronosbio.com/ 2017



of first-in-class therapies that modulate historically recalcitrant cancer targets.

Zumutor Biologics Biotechnology, Therapeutics

Woburn, Massachusetts, United States

Zumutor Biologics is a leading Immuno-Oncology company in the space of targeted NK cell therapeutics. www.zumutor.com/ 2015

Kymera Therapeutics

Biotechnology, Health Care, Therapeutics


A biotechnology company pioneering a transformative new approach to treating previously untreatable diseases. www.kymeratx.com/ 2017

Notable Labs

Biotechnology, Health Care, Test and Measurement

Foster City, California, United States

Notable Labs provides personalized drug combination testing service for cancer patients. www.notablelabs.com 2014

Whole Biome

Biotechnology, Health Diagnostics, Life Science, Medical, Therapeutics


Whole Biome is a microbiome company focused on enabling better patient care through targeted equilibration of human microbiomes.

www.wholebiome.com/

Less than $1M

Sep 29, 2014

Verge Genomics

Biotechnology, Genetics, Health Care, Neuroscience


Verge Genomics uses machine learning and human genomics to accelerate drug discovery

www.vergegenomics.com

$1M to $10M 2015

Caribou Biosciences

Biopharma, Biotechnology, Genetics, Health Care

Berkeley, California, United States

Caribou Biosciences is a biotechnology company in genome engineering. We develop technology-based

www.cariboubio.com/

$1M to $10M 2011



solutions for cellular.

Pivot Bio Agriculture, AgTech, Biotechnology Berkeley, California, United States

Fueled by an innovative drive and a deep understanding of the microbiome, Pivot Bio is pioneering game-changing advances in crop nutrition. www.pivotbio.com/

$1M to $10M 2010

CytoVale Analytics, Biotechnology, Life Science


Categorized under Analytical Instruments, our records show it was established in and incorporated in Massachusetts, current estimates show www.cytovale.com/ 2013

Embark Veterinary

Animal Feed, Biotechnology, Genetics, Health Care, Pet, Veterinary

Boston, Massachusetts, United States

End preventable disease in dogs. embarkvet.com

$1M to $10M

Jul 29, 2015

Shasqi

Biotechnology, Emergency Medicine, Health Care, Manufacturing, Medical


Shasqi develops cancer treatment intended to use bio-orthogonal chemistry for localized drug delivery. www.shasqi.com/ 2015

Nutrafol Beauty, Biotechnology, Consumer Goods, Health Care, Wellness


Nutrafol is a nutraceutical manufacturer that formulates all-natural, drug-free products to improve hair growth. www.nutrafol.com/

Less than $1M

Feb 4, 2014

Athelas

Artificial Intelligence, Biotechnology, Health Care, Life Science

Mountain View, California, United States

Deep learning for biotech. athelas.com/

Jun 1, 2016

Denovo Biopharma Biopharma, Biotechnology

San Diego, California, United States

Denovo Biopharma is a privately held biotech company providing a novel biomarker solution to personalize drug development.

www.denovobiopharma.com/index.html



Nebula Genomics Biotechnology, Blockchain, Genetics


Nebula Genomics leverages blockchain technology to eliminate middlemen and empower people to own their personal genomic data. www.nebula.org 2016

Second Genome

Biotechnology, Health Diagnostics, Medical


Second Genome offers a pipeline of microbiome modulators that impact infection, immunity and metabolic diseases.

www.secondgenome.com

$1M to $10M 2009

Checkerspot

Biotechnology, Manufacturing, Product Design


A materials innovation company.

www.checkerspot.com/

Less than $1M 2016

Immunitas Therapeutics Biotechnology


Immunitas Therapeutics is a single cell genomics-based drug discovery company. www.immunitastx.com/

4D Molecular Therapeutics Biotechnology, Genetics

Emeryville, California, United States

4D Molecular Therapeutics’ mission is to design and develop transformative gene therapy products using our proprietary.

www.4dmoleculartherapeutics.com 2013

Emerald Cloud Lab Biotechnology, Medical, Therapeutics


Emerald Cloud Lab is building technology platforms to drive the future of biotechnology innovation.

www.emeraldcloudlab.com

$1M to $10M 2010

Werewolf Therapeutics Biotechnology, Therapeutics


Werewolf Therapeutics operates as an oncology biotherapeutics company. werewolftx.com/

Tenaya Therapeutics

Biotechnology, Health Care, Therapeutics


Tenaya Therapeutics is dedicated to discovering and developing novel

www.tenayatherapeutics.com/

$1M to $10M 2016



therapies for heart failures.

Solugen Biopharma, Biotechnology, GreenTech, Manufacturing

Houston, Texas, United States

Solugen has developed a unique process for the synthesis of hydrogen peroxide inspired by principles of cancer biology. www.solugentech.com/ 2016

Proscia Inc.

Artificial Intelligence, Biotechnology, Health Care, Life Science, Medical, Pharmaceutical, Software

Philadelphia, Pennsylvania, United States

Proscia is on a mission to perfect cancer diagnosis with intelligent software that changes the way the world practices pathology. www.proscia.com 41821

Compass Therapeutics

Biopharma, Biotechnology, Therapeutics


Compass Therapeutics is a biopharmaceutical company focused on drugging the immune system to treat human diseases. www.compasstherapeutics.com/

Lygos

Advanced Materials, Biotechnology, Clean Energy, Machine Learning


Lygos is providing biotechnology solutions for today’s renewable chemical challenges. www.lygos.com

$1M to $10M

Apr 1, 2010

Carisma Therapeutics

Biotechnology, Health Care, Life Science, Medical, Therapeutics

Philadelphia, Pennsylvania, United States

Carisma Therapeutics is a biotechnology company developing cellular immunotherapies. carismatx.com/ 2016

Verve Therapeutics Biotechnology


Verve is focused on discovering and developing therapies that safely edit the genomes of adults to confer protection against coronary. www.vervetx.com/about-us/ 2018

Arzeda Biotechnology, Information Services, Information Technology

Seattle, Washington, United States

Arzeda develops www.arzeda.com 2008



enzyme design technology to create entirely novel designer cell factories capable of industry-scale chemical production.

Progenity Biotechnology, Health Care, Medical Carlsbad, California, United States

Clinical laboratory services to provide physicians and patients with accurate, timely and state-of-the-art test results. progenity.com/

$10M to $50M 2010

Seven Bridges

Bioinformatics, Biotechnology, Clinical Trials, Cloud Data Services, Genetics, Life Science, Pharmaceutical

Charlestown, Massachusetts, United States

Seven Bridges is the leading biomedical data science company.

www.sevenbridges.com/

$1M to $



National & International Industry Associations Biotechnology Innovation Organization (Bio) 1201 Maryland Avenue SW, Suite 900 Washington, DC, 20024 Tel: 202-962-9200 Web: www.bio.org BIO is the world's largest trade association representing biotechnology companies, academic institutions, state biotechnology centers and related organizations across the United States and in more than 30 other nations. American Institute for Medical and Biological Engineering 1400 I St NW, Suite 235 Washington, DC 20005 Web: www.aimbe.org The American Institute for Medical and Biological Engineering (AIMBE) is a non-profit organization headquartered in Washington, D.C., representing the most accomplished individuals in the fields of medical and biological engineering Biomedical Engineering Society 8201 Corporate Drive, Suite 1125 Landover, MD 20785-2224 Web: www.bmes.org The Mission of the BMES is to build and support the biomedical engineering community, locally, nationally and internationally, with activities designed to communicate recent advances, discoveries, and inventions; promote education and professional development; and integrate the perspectives of the academic, medical, governmental, and business sectors. Engineering in Medicine and Biology Society 445 Hoes Lane Piscataway, NJ 08854 USA Web: www.embs.org IEEE Engineering in Medicine and Biology Society (EMBS) is the world’s largest international society of biomedical engineers. The organization’s 12,000 members reside in some 97 countries around the world. EMBS provides its members with access to the people, practices, information, ideas and opinions that are shaping one of the fastest growing fields in science. Advanced Medical Technologies Association 701 Pennsylvania Ave, N.W., Suite 800 Washington, D.C. 20004-2654 202-783-8700 Web: www.advamed.org The Advanced Medical Technology Association (AdvaMed), is a trade association that leads the effort to advance medical technology in order to achieve healthier lives and healthier economies around the world. AdvaMed’s membership has reached over 400 members and more than 80 employees with a global presence in countries including Europe, India, China, Brazil, and Japan. AdvaMed's member companies range from the largest to the smallest medical technology innovators and companies.The Association acts as the common voice for companies producing medical devices, diagnostic products and health information systems.



International Association of Nanotechnology 1290 Parkmoor Ave San Jose, CA 95126 Web: www.ianano.org The International Association of Nanotechnology (IANT), is a non-profit organization with the goals to foster scientific research and business development in the areas of Nanoscience and Nanotechnology for the benefit of society. The Association fosters friendship, equality and cooperation amongst its members around the world. IANT does not endorse nor support any applications which uses and misuses the advanced technology for destructive purposes.



Regional Industry Associations BioAlabama P.O. Box 929, Huntsville, AL 35804 (256) 542-1019 Web: www.bioalabama.com BIO Alabama represents Alabama's bio related industries, research scientists, clinicians and business professionals who are working together to foster, develop and support the life sciences in Alabama. BIO Alabama is the state affiliate in Alabama of the Biotechnology Innovation Organization (BIO), the preeminent national association for biotechnology companies. Arizona BioIndustry Association 107 S. Southgate Drive Chandler, AZ 85226 (480) 779-8101 Web: www.azbio.org AZBio is a not-for-profit, 501 (c) 6 trade association promoting the growth of Arizona bioscience companies. The Association is comprised of Member organizations in business, research and education, economic development, government, and other professions involved in the biosciences. As the unified voice of the bioscience industry in Arizona, AZBio strives to make Arizona a place where bioscience organizations can grow and succeed. Biocom 10996 Torreyana Road, Suite 200 San Diego, CA 92121-1105 (858) 455-0300 Web: www.biocom.org Biocom works on behalf of over 1,200 members to drive public policy, build an enviable network of industry leaders, create access to capital, introduce cutting-edge workforce development and STEM education programs, and create robust value-driven purchasing programs. Biocom provides the strongest public voice for research institutions and life science companies that fuel the California economy. California Life Sciences Association 250 East Grand Ave., Suite 26 South San Francisco, CA 94080 (650) 871-3250 Web: www.califesciences.org California Life Sciences Association (CLSA) is the trade association representing California’s life sciences industry. CLSA advances California’s world-leading life sciences innovation ecosystem by advocating for effective national, state and local public policies and supporting entrepreneurs and life sciences businesses.



Southern California Biomedical Council 617 South Olive Street, Suite 700 Los Angeles, CA 90014 (800) 418-7079 Web: www.socalbio.org Southern California Biomedical Council (SoCalBio) is a nonprofit, member-supported trade association that serves the biotech, med tech, IVD and digital health communities in the six counties that comprise the Greater Los Angeles region (Los Angeles, Orange, Ventura, Santa Barbara, Riverside and San Bernardino). SoCalBio’s programs help local firms gain access to capital, potential partners, and other business services. The Council also promotes technology transfer and workforce training, while informing policymakers and the public at-large about the benefits of the region’s bioscience industry. SoCalBio is open to membership by firms and organizations engaged in all aspects of bioscience research, technology development, and commercialization. Colorado BioScience Association 600 Grant Street, Suite 306 Denver, CO 80203 (303) 592-4073 Web: www.cobioscience.com BioCT 760 Chapel Street New Haven, CT 06510 203-470-2720 Web: www.BioCT.org BioCT links together the pharmaceutical, bioscience, medical device, healthcare and emerging digital health community in the state. We support the growth of emerging companies and start-ups, as well as the recruitment of new companies and industry services, to continue to expand our ecosystem and the strength of our state economy. Delaware BioScience Association 1 Innovation Way, Suite 300 Newark, DE 19711 (302) 452-1103 Web: www.delawarebio.org Formed in early 2006, Delaware BioScience Association (Delaware Bio) has brought together pharmaceutical and biotechnology firms, medical device manufacturers, agricultural biotech and chemical companies, research and testing companies, hospitals and medical institutions, and other organizations and related service companies, with the shared goal of expanding our state’s vibrant science economy. BioFlorida, Inc. 6742 Forest Hill Blvd., Suite 256 West Palm Beach, FL 33413 (561) 653-3839 Web: www.bioflorida.com BioFlorida is the voice of Florida’s life sciences industry, representing 6,200 establishments and research organizations in the biopharmaceuticals, medical technology, healthIT and bioagriculture sectors that collectively employ 87,000 Floridians.



Georgia Bio 999 Peachtree Street NE, Suite 1800 Atlanta, GA 30309 (404) 221-0617 Web: www.gabio.org Georgia Bio (GaBio), founded in 1989, is a non-profit, membership-based organization that promotes the interests and growth of the life sciences industry. It is the state’s largest and most influential life sciences advocacy and business leadership organization which works to improve access to innovative technologies and grow Georgia’s life sciences economy. Members include companies, universities, research institutions, government groups and other industry associations involved in discovery and application of life sciences products and related services that improve the health and well-being of people throughout the world. Iowa Biotechnology Association 500 E Court Ave., Suite 112 Des Moines, Iowa 50309 Web: www.iowabio.org The Iowa Biotechnology Association, a 501(c)6 non-profit trade association, was founded in 1994 to unify Iowa's bioscience industry, academic research institutions and economic development organizations. We represent more than 100 members spanning across our state, who are vested in Iowa and in the biotech industry. Idaho Technology Council 101 S. Capitol Blvd. Suite 208 Boise, ID 83702 (208) 917-5184 Web: www.idahotechcouncil.org The mission of the Idaho Technology Council is to help companies in Idaho start, grow, and thrive. ITC’s member-driven organization includes partners ranging from growing companies, mid-size companies, and large corporations, all committed to the success of Idaho’s technology ecosystem. Illinois Biotechnology Innovation Organization (iBIO) 150 South Wacker Drive, Suite 3125 Chicago, IL 60606 (312) 422-1111 Web: www.ibio.org iBIO is a life sciences industry association that represents the 85,000 life sciences employees at member companies, universities, service providers and venture firms. iBIO promotes the industry’s value to the public and policymakers; connects innovators to investment and talent; stimulates collaboration and fosters the next generation of innovators and entrepreneurs to transform patient lives through groundbreaking research and works to grow the Illinois economy. Indiana Health Industry Forum 429 E. Vermont Street, Suite 304 Indianapolis, IN 46202 (317) 752-9809 Web: www.ihif.org IHIF is a statewide trade association representing Indiana’s health science business community. The diverse members of the Indiana Health Industry Forum generate the collective voice of the state’s health and life science industry. Our mission is to connect key stakeholders to: enhance business networks, advocate for member interests, develop workforce skills, and provide strategic vision in the interest of growing the state’s health industry economy and reputation.



BioKansas 4220 Shawnee Mission Parkway, Suite 350-B Fairway, KS 66205 (913) 495-4334 Web: www.biokansas.org BioKansas is the unified voice representing the biosciences in Kansas. Across the human, plant, animal and industrial biosciences, BioKansas is focused on enhancing the business and research climate and working with leaders across the state to attract and retain bioscience talent, companies and funding. Kentucky Life Sciences Council 3006 Whiteway Ave. Louisville, KY 40205 (859) 415-4949 Web: www.kysciencecouncil.org KLSC provides innovation services and advocacy on behalf of Kentucky’s life science community. LouisianaBio 1441 Canal Street, Suite #212 New Orleans, LA 70112 (504) 598-5239 Web: www.louisianabio.org Louisiana Bio is an independent, non-profit 501(c)(3) trade association whose mission is to be the voice of Louisana’s life sciences industry and research organizations in the biosciences, pharmaceuticals, medical technology (devices and diagnostics), health IT and bio-agriculture sectors. To accomplish this mission, Louisiana Bio works on behalf of member organizations to drive public policy, create access to capital, introduce cutting-edge STEM education programs, build a network of industry leaders, and create robust value-driven purchasing programs. Massachusetts Biotechnology Council 300 Technology Square, 8th Floor, Cambridge, MA 02139 Web: www.massbio.org MassBio represents 1,200+ life sciences companies and organizations involved with the industry. We are available to comment and provide background on public policy, economic development, education, workforce development and other key life sciences issues. Maryland Life Sciences 9841 Washingtonian Boulevard, Suite 200 Gaithersburg, MD 20878 (240) 243-4026 Web: www.mdtechcouncil.com At the Maryland Tech Council, we believe in saving lives, securing our nation and improving the quality of life through innovation. We support our member companies who are driving innovation through advocacy, education, workforce development, cost savings and connecting entrepreneurial minds.



Bioscience Association of Maine (BIOME) PO Box 3362 Portland, ME 04104 (207) 307-2552 Web: www.mainebioscience.org BioME is a trade association devoted to promoting growth and development of Maine’s life science industry and serving its members and bioscience community by providing a network for public policy, industry advocacy and economic development. From promising start-ups to established corporations, BioME provides opportunities for innovation, collaboration and promotion of the life science, biotechnology and device manufacturing sectors in Maine. MichBio P.O. Box 130199 Ann Arbor, MI 48113-0199 (734) 527-9150 Web: www.michbio.org Our mission encompasses broad industry sub-sector representation including pharmaceuticals and therapeutics (human and animal health, generics and OTCs), medical devices, diagnostics, research tools, informatics (healthcare and bio-informatics), nutritional health (nutriceuticals), clinical research, industrial biotechnology, and bio-fuels and bio-agriculture. Medical Alley Association 4150 Olson Memorial Highway, Suite 430 Golden Valley, MN 55422 (952) 542-3077 Web: www.medicalalley.org Founded in 1984, the Medical Alley Association supports and advances the global leadership of Medical Alley’s healthcare industry, and its connectivity around the world. MAA delivers the collective influence, intelligence and interactions that support Medical Alley. Rhode Island Bio 24 Corliss Street #41240 Providence, RI 02904-2477 (401) 400-5499 Web: www.ri-bio.org Founded in 2013, RI Bio is southeastern New England’s life sciences industry group. We are dedicated to galvanizing collaboration and growth among life sciences companies, hospitals, universities, sources of capital and governmental partners. We convene, catalyze and advise. With the support of our partners, we work to secure resources to support the life sciences community and provide our members with exclusive access to regional/industry news, events, materials and supplies, workspaces, growth partners, training, and more. Missouri Biotechnology Association 428 East Capitol, Ste 300 Jefferson City, MO 65102-0148 (573) 761-7600 Web: www.mobio.org The Missouri Biotechnology Association (MOBIO) is the state's premier professional business association dedicated to growing and protecting Missouri's bioscience and high tech companies. MOBIO provides focused legislative engagement, valuable connections across the converging industries, a forum for addressing emerging science talent shortages, new pathways as our businesses strive for capital growth and access to funding, and important cost-savings solutions.



Montana BioScience Alliance 1500 University Drive Apsaruke Hall #111, Billings, Montana 59101 (406) 896-5876 Web: www.montanabio.org The Montana Bioscience Alliance serves as a hub for Montana’s biotechnology companies, entrepreneurs, laboratories, hospitals, clinics and universities to commercialize, grow and sustain globally competitive bioscience companies — ultimately to create high-quality jobs and economic opportunity in Montana. North Carolina Biosciences Organization (NCBIO) PO Box 14354 Research Triangle Park, NC 27709 (919) 281-8960 Web: www.ncbioscience.net NCBIO is dedicated to promoting the future growth and development of North Carolina’s bioscience industry. NCBIO advocates for state and federal public policies that encourage the growth of life science companies, supports the development of a strong life science workforce, promotes research and technology transfer at universities and other institutions including support for capitalization and commercialization of products. Bioscience Association of North Dakota (BioND) 4200 James Ray Drive Suite 500 Grand Forks, North Dakota 58201 (701) 738-2431 Web: www.ndbio.org Formed in 2010, the Bioscience Association of North Dakota (BioND) is diligently working for the development of bio companies through startup and expansion of bio-based ventures in life sciences, bio-ag, bio-materials, bio-fuels and related entities. BioND provides leadership and vision with a voice in state and national forums. We have created an entrepreneurial organization that is helping an industry grow and flourish in North Dakota. Bio ND promotes the creation of an entrepreneurial culture for bioscience and biotechnology research and business development in the agriculture, life and energy science fields while concurrently nurturing growth and economic opportunities in North Dakota. Bio ND is dedicated to expanding the boundaries of bioscience to commercialize, grow and sustain globally competitive bioscience companies, benefiting mankind and creating jobs in North Dakota. Bio Nebraska Life Sciences Association PO Box 24802 Omaha, NE 68124 (308) 440-8828 Web: www.bionebraska.org Bio Nebraska Life Sciences Association (Bio Nebraska) was formed in 2005 as a nonprofit trade association dedicated to the development and growth of Nebraska’s bioscience industry through: • Supporting basic research in the life sciences • Aiding in the development of a highly educated work force; and • Providing a welcoming environment for attracting new and expanding businesses



BioNJ 1255 Whitehorse-Mercerville Road, Building B – Suite 514 Trenton, NJ 08619 (609) 890-3185 Web: www.BioNJ.org As the life sciences association for New Jersey, BioNJ is a powerful network of 400 Member companies representing research-based life sciences companies and stakeholders. Because Patients Can’t Wait®, we are dedicated to propelling the rich innovation ecosystem in the New Jersey region to stimulate and support innovation, improve and save lives, and lower the hurdles of healthcare advancements for society. New Mexico Biotechnology & Biomedical Association P.O. Box 31516 Sante Fe, NM 87594 (610) 731-3671 Web: www.nmbio.org NMBio is New Mexico’s statewide trade association for biotechnology, biomedicine, and related industries. For over twenty years, NMBio has supported the needs of companies in pharma/biotech, diagnostics, medical devices, nutraceuticals, scientific instrumentation/manufacturing, and biofuels/agriculture. In addition, it fosters networking and partnership with the state’s universities, research institutes, and national laboratories. NMBio provides a forum for information exchange related to life science activities, develops initiatives to enhance small business success, provides education regarding the biosciences, helps establish collaboration, and publicizes New Mexico’s bioscience industry. Nevada Biotechnology & Health Science 9501 Royal Windsor Ave Las Vegas, NV 89149 (623) 256-0503 Web: www.nevbio.org NevBio has built strong alliances within Nevada, across our great country as well and internationally over the last 6 years. As the Nevada affiliate of Bio, NevBio can connect you or your organization with State Bio groups, industry leaders and drivers of economic development. We have built relationships across the country within business, government and universities that have resulted in new jobs in Nevada, relocation of companies to Nevada and introductions to key individuals from around the world. NewYorkBIO 430 E. 29th Street, 14th Floor New York, NY 10016 (646) 440-9016 (404) 702-6007 Web: www.newyorkbio.org NewYorkBIO supports the development and growth of New York State’s life science industry, and serves its members and the life science community by providing a network for public policy, industry advocacy, and community development.



BioOhio 1275 Kinnear Road Columbus, OH 43212 (614) 675-3686 Web: www.BioOhio.com BioOhio connects and serves Ohio’s bioscience community to drive success in improving global quality of life. Oregon Bioscience Association 2828 SW Corbett Ave , Suite 115 Portland, OR 97201 (503) 548-4432 Web: www.oregonbio.org Oregon Bio, a member trade association, was formally established as a 501(c)(6) non-profit in 1989 by a consortium of universities, public officials, educators and bioscience executives to cultivate a regionally synergistic climate in which to build a bioscience community. Today, Oregon Bio supports the regional bioscience community through networking, workforce development, educational programs, enterprise support, advocacy and the promotion of research collaborations. Life Sciences Pennsylvania 650 East Swedesford Road, Suite 190 Wayne, PA 19087 (610) 947-6800 Web: www.lifesciencespa.org Life Sciences Pennsylvania (LSPA) is the trade association for the Commonwealth’s life sciences community. Founded in 1989, we work to ensure Pennsylvania has a business and public policy climate that unites and incentivizes all facets of the state’s diverse life sciences economy. LSPA represents biotechnology, medical device, diagnostic, pharmaceutical, research, and investment entities, along with myriad service providers who support the industry. Together, we unify Pennsylvania’s innovators to make the Commonwealth a global life sciences leader. INDUNIV PRIDCO Bldg, Suite 101PO Box 362350 San Juan, PR 00936-2350 (787) 772-4604 Web: www.induniv.org Founded in 1985, INDUNIV is a nonprofit organization [IRC Section 501(c) (3)] representing industry, government and the academic sector. The consortium promotes the island’s competitiveness in science and technology. Its efforts pave the way for the knowledge economy.. INDUNIV advances understanding of the pharmaceutical and bioscience development fields; facilitates collaboration between industry, government and academia; develops strategies and road maps to formulate public policy and advocates its implementation. It is a relentless promoter and catalyst for the development of centers of excellence, technology parks and incubators to head in the value chain for the innovation through commercialization of products, enhancing Puerto Rico’s competitiveness and making it more attractive for manufacturing activities.



SC BIO Suite 304, Legacy Square 340 Rocky Slope Road Greenville, SC 29607 (864) 313-2277 Web: www.scbio.org A statewide, not-for-profit, public/private life sciences industry association and economic development organization formed to actively promote, build, support, expand, and convene South Carolina's life sciences industry. South Dakota Biotech Association 2329 N. Career Avenue, Suite 115 Sioux Falls, SD 57107 (605) 274-3714 Web: www.sdbio.org Formed in 2006, South Dakota Biotech serves a membership which includes business, universities, service providers and state-wide economic development entities to expand the bioscience industry. The primary goals of the association are to: • Connect leaders and experts. • Collaborate to shape the future. • Drive innovation to feed, fuel, and heal the world. Life Science Tennessee 217 Fifth Avenue North, Suite 200 Nashville, TN 37219 (615) 242-8856 Web: www.lifesciencetn.org Life Science Tennessee is a statewide, non-profit, member organization of more than 100 companies whose mission is to advance and grow the life science industry in Tennessee through advocacy, partnerships and alignment with economic and workforce development. Members include companies, universities, research institutions, government and economic development groups and other industry associations involved in the discovery and application of life science products and related services that improve the health and well-being of people throughout the world. Texas Healthcare Bioscience Institute (THBI) 815 Brazos Street, Suite 310 Austin, TX 78701 (512) 708-8424 Web: www.thbi.com The Texas Healthcare and Bioscience Institute (THBI) is the Texas public policy voice for the healthcare and bioscience industry. THBI is spearheading the path to position Texas as a global leader within the biotechnology and life sciences industries.



BioUtah PO Box 58531 Salt Lake City, UT 84158-0531 (801) 867-4061 Web: www.bioutah.org BioUtah is an independent, non-profit 501(c)(6) trade association serving the life sciences community in the state of Utah. We are comprised of manufacturers and developers of medical devices, pharmaceuticals, diagnostics and biotechnology products as well as government, academic and health care institutions all focused on improving health and wellness through the delivery of innovative technologies and services. We also count among our members those who support our industry such as national trade associations and key service providers. Together we create a community that fosters collaboration, promotes innovation, and accelerates health care advances to save lives and improve the quality of life. Virginia Biotechnology Association 800 East Leigh Street, Suite 14 Richmond, VA 23219 (804) 643-6360 Web: www.vabio.org Virginia Biotechnology Association is a member driven organization. Together, we create a network of leaders generating growth for bioscience in the Commonwealth. We are the drivers of innovation to improve lives. We excel cutting-edge research and commercialization, connect members to venture capital and other sources of funding, connect academia and industry, and accelerate the growth of economic development for the Virginia bio-ecosystem. Vermont Biosciences Alliance P.O. Box 2104 South Burlington, VT 05407 Web: www.vtbiosciences.org Mission: To foster recognition of medicine and bio-science as a leading industry in the Vermont region and promote economic and human well-being by strengthening sector attention, research resources and venture growth. Life Science Washington 1551 Eastlake Avenue East , Suite 300 Seattle, WA 98102 (206) 456-9567 Web: www.lifesciencewa.org Life Science Washington is an independent, non-profit 501(c)(6) trade association whose mission is to stimulate life science innovation, job creation and ecosystem vibrancy across Washington state through engagement, collaboration, promotion, and advocacy. BioForward Wisconsin 214 N Hamilton, Suite 202 Madison, WI 53703 (608) 236-4693 Web: www.bioforward.org BioForward serves as the independent voice of Wisconsin’s biohealth industry, providing services and resources to support the growth of our industry throughout the U.S. and the world. BioForward is the only Wisconsin organization representing over 200 biohealth member companies including biotech, biopharma, medical device, diagnostics, digital health, as well as research institutions, and service providers.



Bioscience Association of West Virginia PO BOX 20065 Charleston, WV 25362 (304) 529-0803 www.biowv.org BioWV, the Bioscience Association of West Virginia, was formed in 2009 and incorporated in the State of West Virginia as a non-profit association. The purpose of the Association is to promote the bioscience industry in West Virginia, expand the knowledge and expertise of West Virginia’s businesses concerning the life sciences through seminars, educational publications and to enhance public awareness of the biotechnology industry in West Virginia. BioWV represents the interests of the bioscience industry in West Virginia before federal, state and local legislators and regulators.

USA-Based Industry Conferences & Trade Shows BIO International Convention Jun 8-11, 2020・San Diego Convention Center Website: https://www.bio.org/events/bio-international-convention/register The BIO International Convention is hosted by the Biotechnology Innovation Organization (BIO). BIO represents more than 1,100 biotechnology companies, academic institutions, state biotechnology centers and related organizations across the United States and in more than 30 other nations. BIO members are involved in the research and development of innovative healthcare, agricultural, industrial and environmental biotechnology products. SPIE BiOS20 – Biomedical Optics | Part of SPIE Photonics West 2020 01 Feb 2020 - 06 Feb 2020San Francisco, United States Website: http://SPIE.org/bios_conf_cs BiOS 2020, part of SPIE Photonics West 2020, is the world’s largest biomedical optics and biophotonics conference. Topics range from biomedical optics, photonic diagnostic and therapeutic tools and systems, nano/biophotonics, new imaging modalities, OCT, neurophotonics, optogenetics, and tissue optics. CHI's 2nd Annual Bio-IT World Conference & Expo WEST 01 Mar 2020 - 04 Mar 2020 • San Francisco, United States https://www.bio-itworldexpowest.com Pharmaceutical companies are undergoing a digital transformation. By experimenting with new initiatives, they are positioned to play a role in the revolution of healthcare. This transformation is driven by data from internal and external sources, including both -omic data and that from digital devices. Bio-IT World WEST, part of Molecular Medicine Tri-Conference, brings together all the stakeholders involved in this transformation. Antibody Biology and Engineering 13 Mar 2020 - 20 Mar 2020 • Ventura, CA, United States https://www.grc.org/antibody-biology-and-engineering-conference/2020/ Related subject(s): Molecular Biology, Immunology and Allergic Diseases

Documents

th Qtr. 2019 BIOTECHNOLOGY STARTUPS RESEARCH REPORT · The Biotechnology Innovation Organization, or BIO, the largest biotechnology industry organization in the United States, subdivides