BOOK REVIEWS 62 1 the terminal web upset. After 12 months disappearance of the glycocalyx, increased lysosomal features, increased activity of the muciparous cells, rounded mitochondria and loss of the polarized disposition of the cytoplasmic organelles were detected in the enterocytes. We observed no other substantial change aRer 24 months and more. Conclusions: Progressive modifications occur in the cytoplasmic structures involved in the absorptive process. They do not seem to begin before 3 months and are almost totally completed after 1 year.

Editorial Comment: Although animal models have been constructed for investigation of in- testinal segments in the urinary tract, there are less clinical data. These authors followed 15 patients with an ileal neobladder. Significant changes were observed after 6 months, including prominent loss of microvilli and loss of polarized disposition of the cytoplasmic organelles. The urinary environment for these neobladders does appear to change the mucosal characteristics. We found similar findings in a rat model.’ In addition, there may also be changes in active transport. Some of these findings become increasingly important for drug metabolism. Any drug that has oral absorption and renal secretion must be more carefully considered because of the pharmacodynamics of changed drug metabolism in these patients.

Fray F. Marshall, M.D. 1. Burnett, A. L, Donowitz, M. and Marshall, F. F.: Inhibition of transport processes of intestinal segments

following augmentation enterocystoplasty in rats. J. Urol., 156: 1872,1986.

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Urologic Oncology J. E. OESTERLING AND J. P. RICHIE, Philadelphia: W. B. Saunders, Co., 801 pages, 1997

With the publication of Urologic Oncology, urologists may now avail themselves of another contemporary resource for the resolution of a broad range of urological oncological problems. This multiauthored textbook addresses issues as fundamental as the molecular and cellular biology of urological cancers, and as practical as the latest specifics associated with the performance of female orthotopic neobladder after nerve sparing anterior pelvic exenteration.

All major areas of urological oncology are covered in detail by noted experts in the field. Particularly useful for students and residents in training are sections on the basic principles associated with surgical oncology and the application of allied modalities of therapy, such as medical oncology and radiation therapy. An interesting summary of the basic principles of immunotherapy is presented as part of this section. In addition to the management of adult malignancies in common systems, such as the bladder, kidney and prostate, the authors have addressed the concerns of pediatric uro-oncologists. A separate section of this book addresses common pediatric tumors and their management. Also, particularly helpful for students and urologists in training is a section entitled, “Additional Topics,” in which issues, such as the application of laparoscopy in urological oncology, are detailed. The chapter entitled, “Creative Modalities,” describes innovative imaging of the genitourinary tract as applied to the diagnosis and management of various cancers. This compendium of contemporary information and advice will no doubt be a welcome addition to the

library of practicing urologists and urologists in training. A particularly noteworthy aspect of this volume is the attention to additional useful topics, such as nutritional issues for the cancer patient, anesthesia in cancer surgery and pain control in the terminally ill individual. For urologists interested in understanding the contemporary literature and for those aspiring to careers as clinical trialists, the chapter on the randomized clinical trial that concludes the book should provide a valuable resource.

Mark P. Schoenberg, M.D. Brady Urological Institute

Textbook of Uroradiology, 2nd ed. Johns Hopkzns Hospital Baltimore, Maryland

N. R. DUNNICK, C. M. SANDLER, E. S. AMIS, JR. AND J. H. NEWHOUSE, Baltimore: Williams & Wilkins, 520 pages, 1997 The authors of this single volume text are renowned uroradiologists who are to be complimented on

producing a textbook that is an admirably updated amalgamation of their 2 previously competing texts of uroradiology.l.2 The stated goal was to produce a book that would address ”what one ought to know, rather than what there is to know,” which is amply met in this well written and profusely illustrated textbook, reasonably priced and of manageable size.

The book is organized into 20 chapters, of which the first 4 cover basic anatomy, embryology and physiology of the urinary tract. Chapter 4 is a comprehensive review of commonly used intravascular contrast media, adverse reactions to contrast agents and the management of such reactions, which should

622 BOOK REVIEWS

be required reading for all urology and radiology residents. Chapters 5 through 13 cover the gamut of renal pathology. Chapter 14 is a superb review of upper and lower urinary tract trauma. The remaining chapters address the adrenal gland and the lower urinary tract as well as the male genital tract. Line diagrams are liberally dispersed throughout the text, and serve to complement and amplify the generally high quality illustrations. Disease processes are appropriately demonstrated by the currently available modalities useful in the imaging of the genitourinary tract, such as ultrasound, computerized tomography and magnetic resonance imaging.

The shortcoming of the book is the brief 6 pages allocated to interventional techniques in a combined chapter (3) that addresses diagnostic and interventional techniques. "here are no other major omissions. Although not intended to be a reference textbook, it is remarkably complete and an easy to read volume that should be read in its entirety by radiology and urology residents. Practicing radiologists and urologists will also find this gem to be a valuable resource, and a model of completeness and clarity. It deserves a place in the libraries of all radiology and urology departments.

Paruati Ramchandani, M.D. Department of Radiology University of Pennsylvania Medical Center Philadelphia, Pennsylvania

1. Dunnick, N. R, McCallum, R W. and Sander, C. l b k Textbook of Uroradiology. Baltimore: Williams &

2. Amis, E. S., Jr. and Newhouse, J. H.: Essentials of Umradiology. Boston: Little, Brown and Co., 1991. wilking 1991.