Texas Biotech Report 2012

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The Texas

Biotechnology Industry2013

Office of the Governor | Economic Development & Tourism



Overview…………………………………………………………………

Medical Devices……………………………………………………...

Pharmaceuticals………………………………………………………

Biomedical Research……………………………………………….

Agricultural & Animal Biotech…………………………………

Environmental Tech & Biofuels……………………………….

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Contents

Texas at the BIO

International Convention

The State of Texas and the Texas

Healthcare and Bioscience Institute, an

industry advocacy group, work to

promote the advancement of the

state’s biotechnology industry by

exhibiting at the annual Biotechnology

Industry Organization (BIO) Interna-

tional Convention. A Texas delegationof government officials, community

representatives, and industry leaders

hosts a booth and meets with biotech

business leaders from around the

world.

Texas Gov. Rick Perry at 2012 BIO International Convention in Boston



Texas Biotech Headlines

Alcon Laboratories begins $15 millionexpansion at multiple Fort Worth facilities

Allergan installs new

production line at Waco, TX,

pharmaceutical

plant, expands

local workforce

Merit Medical breaks ground

on $14 M plant in Pearland, TX

Texas ranks #2 for

employment of life

and physicalscientists

nationwide

Texas public

institutions award

over 50,600biotech-related

degrees

from 2009-

2012

Texas A&M partners with

GlaxoSmithKline to lead one of

three national

biodefense labs

Fort Worth’s Healthpoint

Biotherapeutics purchased by

British medical device giant

Smith & Nephew

See Page 12

See Page 13 See Page 7

See Page 8See Page 3 See Page 18

See Page 13See Page 6

Medical device firm

Greatbatch

relocates HQ fromNew York to Frisco,

Texas



Biotechnology is technology based on biologywhich harnesses cellular and molecular

processes to develop products that help

improve the health of humans and the planet. People

have used the biological processes of microorganisms

for more than 6,000 years to make and preserve food

products. Modern biotech provides breakthrough tools

to combat diseases, increase crop yields, and develop

cleaner energy sources.

Because of the breadth of biotechnology activities, the

field actually encompasses many related industries,

from medical, to chemical, to agricultural. Within the

North American Industry Classification System

(NAICS), the federal standard for classifying busi-

nesses, biotechnology spreads across the ten subsec-

tors listed below.

The Biotechnology Industry

As home to over 3,500 biotechnology manufacturing

and R&D firms, Texas is one of the leading biotech

states in the country. More than 89,600 workers are

employed in biotech-related sectors in Texas, and

dozens of global biotech companies, such as Novartis,

Abbott, and Medtronic, have major operations in the

state. A concentration of highly trained biotech

workers, multiple top-tier research institutions, and a

top-ranked business climate all strengthen the state’s

status as a biotechnology leader.

In 2011, approximately one out of every 15 U.S.

biotechnology establishments was in Texas, according

to the U.S. Bureau of Labor Statistics (BLS). Irving-

based Kimberly Clark and Dallas-based Celanese,

both on the 2012 Fortune 1000 list, are among the

largest biotech-related companies headquartered in the

state.

The total economic impact of the biotechnology

industry in Texas in 2009 was estimated at $75

billion, according to the Texas Healthcare & Biosci-

ence Institute, an industry association. Additionally,

for every biotechnology job created, another 2.3 jobs

were created elsewhere in the Texas economy.

1

Research and Development in Biotechnology

Research and Development in Physical,

Engineering, and Life Sciences

Pharmaceutical and Medicine Manufacturing

Medical Equipment and Supplies Manufacturing

Electromedical Apparatus Manufacturing

Analytical Laboratory Instruments Manufacturing

Medical and Diagnostic Labs

Testing Laboratories

Pesticides, Fertilizer & Other Agricultural

Chemical Manufacturing

Other Basic Organic Chemical Manufacturing

Biotechnology Subsectors

Biotechnology in Texas

89,610Number of biotech

workers in Texas:



Sources: D&B, US FDA, company websites

Selected firms with corporate management, research, or manufacturing facilities in the state

Top Life Sciences Companies in Texas

2

OVERVIEW



Texas is home to over 3,500 firms involved in bio-

technology-related manufacturing, scientific research,and laboratory analysis. These firms employ more

than 89,600 workers at an average annual salary of

nearly $73,400. The table on page 4 provides a snap-

shot of the Texas biotechnology industry as of third

quarter (Q3) 2012. The state has seen overall increases

in the number of biotechnology firms and employment

as well as a slight decrease in average annual wages

since a year prior, in Q3 2011.

In 2010, Texas ranked No. 2 among all U.S. states for

the number of life and physical scientists employed,

with 48,850, according to the National Science Foun-dation (NSF). Additionally, in 2008, Texas ranked No.

3 nationally for employed science, engineering, and

health doctorate holders, with 39,900, according to the

NSF.

Texas Biotech Workforce

Texas Biotech-Related Employment 5-Year Trends

Source: Texas Workforce Commission

Private sector employment only. Data from third quarter of each year .

OVERVIEW

15,000

10,000

5,000

20,000

25,000

20122011201020092008

E m p l o y m e n t

3



Texas Biotech Employmentby Sector



Biotechnology Employment in Texas

Third Quarter 2012

Sector (Industry Code) Employees FirmsAverage

Annual WageMedical and Diagnostic Labs (6215) 18,387 822 $55,172

R&D in Physical, Engineering, and Life Sciences (541712) 15,792 609 $83,668

Testing Laboratories (54138) 15,245 746 $62,712

Medical Equipment and Supplies Manufacturing (3391) 11,496 701 $49,816

Pharmaceutical and Medicine Manufacturing (3254) 10,013 119 $100,308

Other Basic Organic Chemical Manufacturing (32519) 7,416 83 $105,820

R&D in Biotechnology (541711) 4,613 314 $89,908

Pesticides, Fertilizer, and Other Agricultural Chemical Mfg. (3253) 3,079 80 $76,024

Electromedical Apparatus Manufacturing (334510) 2,054 51 $79,040

Analytical Laboratory Instruments Manufacturing (334516) 1,515 31 $76,908

TOTALS 89,610 3,556 $73,443

In Q3 2012, 37% of Texas’ biotech-related workers

were engaged in medical and testing labs (NAICS

6215 and 54138), 23% in scientific R&D (NAICS

541711 and 541712), 17% in devices and equipment

manufacturing (NAICS 334510, 334516, and 3391),

12% in agricultural and other basic organic chemical

manufacturing (NAICS 32519 and 3253), and 11% in

pharmaceutical and medicine manufacturing (NAICS

3254).

From Q3 2008 to Q3 2012, the most recent five years

of available data, biotechnology-related employment

in Texas decreased almost 1% (see graph on previous

page). The medical and diagnostic labs segment saw

continuous employment increases each year duringthat period with almost 10% total growth, while test-

ing labs experienced the greatest overall employment

increases, growing 18.6% between 2008 and 2012.

OVERVIEW

4



Business Incentive Programs

In 2003, the Texas Legislature created the $295

million Texas Enterprise Fund (TEF), a “deal closing”

fund created to attract businesses and new jobs to

Texas. The Legislature reauthorized the TEF most

recently in 2011. As of January 2013, the TEF has

awarded over $98.1 million to biotechnology-related

projects. The table on page 6 details these projects

and the 11,451 jobs they

have committed to create.

In 2005, the Texas Legisla-

ture founded the $200

million Texas Emerging

Technology Fund (TETF) to

promote the commercializa-

tion of technological innovations across multiple

industries, including biotechnology. The TETF was

reauthorized most recently in 2011. To date, the fund

has invested $277.9 million into biotechnology-related

deals, with $127 million going to commercialize start-

up companies and $150.9 million awarded to universi-ties and related consortiums. For a full list of TETF

biotech deals, see page 31.

Education & Research

In 2005, the Texas Legislature

established the Texas Science,

Technology, Engineering and

Mathematics (T-STEM) Initia-

tive. Modeled on national STEM

programs, T-STEM focuses on

educating and graduating moreTexas students in STEM fields

critical for maintaining a skilled,

competitive state workforce. In

part, T-STEM aims to more

OVERVIEW

State Government

Initiatives

closely align high school curricula with admissions

requirements for competitive colleges. Under the

initiative, 51 T-STEM Academies have been created,

serving approximately 15,000 Texas students annu-

ally. For more details on biotech-related education,

see pages 17-26.

Stem Cell Regulation

In April 2012, the Texas Medical Board approved new

guidelines for the use of experimental stem cell

therapies. The guidelines stipulate that the stem cell

procedures are done for research only, that they

receive approval from a public or private institutional

research board, and that patients sign consent forms.

Texas joins other states such as California, New York,

and Illinois in the enactment of rules governing stemcell research.

The Texas EmergingTechnology Fund hasinvested $278million in more than100 biotech deals

$1.4 billionAmount invested by venture capital firms from

2007-2012 in 161 Texas biotech and medical

device deals. (PricewaterhouseCoopers)

Texas A&M Center for Innovation in Advanced Development and Manufacturing

5



Texas Enterprise Fund

Biotechnology-Related Awards

Company DescriptionAward

(Millions)City Jobs

Baylor College of Medicine Bovine gene-mapping project $2.0Houston N/A

Becton, Dickinson & Co.Global professional services for

medical devices$1.56San Antonio 296

Cardiovascular SystemsArterial disease medical devices

manufacturing facility$0.6Pearland 100

Ferris Manufacturing Medical products manufacturing $.45Fort Worth 100

G-Con, LLC Pharmaceutical manufacturing $3.0Bryan 408

Grifols, Inc.Plasma testing laboratory &

fractionation plant$0.5San Marcos 190

Hanger Orthopedic GroupHeadquarters relocation of orthotic and

prosthetic patient care services firm$1.5Austin 236

Medtronic, Inc. Diabetes division expansion $6.0San Antonio 1,384

Scott & White Memorial HospitalCancer Research Institute and other

research initiatives$7.5Temple 1,485

Texas Institute for Genomic

Medicine & Lexicon Pharma.

Genome mapping and “knockout”

mouse cell line library$50.0

College Station

& Houston5,000

The University of Texas Health

Science Center at Houston, M.D.

Anderson, & G.E. Healthcare

HoustonThe Center for Advanced Diagnostic

Imaging$25.02,252

TOTAL 11,451 $98.11

Texas A&M Leads One of Three National Biodefense Centers

In June 2012, the U.S. Department of Health and

Human Services announced locations in North

Carolina, Maryland, and Texas for three new

Centers of Innovation in Advanced Development

and Manufacturing. Created as public-private

partnerships, the centers will help develop re-

sponses to bioterrorism, natural pandemics, and

other health threats.

The Texas A&M University System was designated

to lead the Texas center, in collaboration withGlaxoSmithKline Vaccines, Kalon Biotherapeutics,

and Lonza (see photo, opposite page). The $285

million contract, which can be renewed for up to 25

years, includes an initial investment of $176 million

from the U.S. government, with the remainder

coming from commercial and academic partners,

as well as $40 million from the Texas Emerging

Technology Fund.

When the centers are fully operational, they will

develop and produce vaccines and medicines,

speed biosecurity products to market, and train

biopharmaceutical and related professionals. The

Texas A&M center also furthers Texas’ position as

the “third coast” of the biopharma industry.

OVERVIEW

6



Many of the biggest players in the medicaldevice industry have corporate facilities

in Texas. More than a dozen Fortune

1000 medical device giants alone have manufacturing

or management operations in the state, including

Abbott Laboratories, Agilent Technologies, GE,

Johnson & Johnson, Medtronic, St. Jude Medical,

Stryker, and Thermo Fisher Scientific.

These companies and many others have developed a

large medical device workforce in the state. Approxi-

mately 800 firms employ

more than 15,000 workers

in this sector, and as a

result, Texas is one of the

top 10 states in the nation

for number of medical

device workers. In the

advanced subsector of electromedical instrument

manufacturing, employment in Texas increased more

than 11% from 2008-2012, despite the intervening

recession.

A wide range of medical products are developed and produced in Texas, from surgical sutures and ban-

dages to molecular biology kits and medication

delivery systems. While a broad spectrum of medical

specializations are served by Texas device companies,

the state has developed several unique clusters,

including ophthalmology, orthopedics, cardiology,

diagnostics, and wound care (see page 9 for details).

In 2011, the total value of Texas medical equipment

shipments exceeded $3.2 billion, with manufacturers

making total capital investments of over $100 million,

according to the U.S. Census Bureau. Additionally,

international exports of medical devices from Texas

increased almost 4% in 2012 to $2.3 billion.

Emerging Technology and Venture Capital

From 2007-2012, venture capital (VC) firms invested

approximately $550 million in 89 Texas medical device

deals, according to consulting firm Pricewaterhouse-

Coopers. Thirteen of those investment deals occurredin 2012 alone, with a total of nearly $100 million

invested in Texas medical device companies that year.

Since 2005, the state’s Texas Emerging Technology

Fund (TETF) has invested more than $76 million in

medical device-related deals. (See page 31 for listing.)

Medical Devices

More than a dozenFortune 1000medical devicegiants have majoroperations in Texas

Merit Medical to Open R&D and

Manufacturing Facility in Pearland

In October 2011, Utah-based Merit Medical

Systems announced plans for an 18,000 sq. ft.

research and manufacturing facility in Pearland,

Texas. The facility is scheduled to open by the end

of 2013 and will employ an estimated 220 work-

ers.

Merit selected Pearland after a multi-state site

search and is the second medical manufacturing

facility to recently locate in Pearland, following on

the heels of Cardiovascular Systems in 2010. Merit

Medical is a global firm that develops and manu-

factures proprie-

tary disposable

medical devices

used primarily in

cardiology,

radiology and

endoscopy.

7



The map below identifies the state’s Workforce

Development regions with above-average specializa-

tions in medical equipment manufacturing. The high-

lighted regions are not the only areas in Texas where

workers in this sector can be found, but rather repre-

sent areas with the greatest concentrations

relative to the size of the local labor force. This analysis

compares the portion of each Texas region’s work-

force employed in the sector to the portion of the en-

tire U.S. workforce employed in that sector. The

comparison provides a ratio that measures how inten-

sively a certain region is specialized in this industry,

and ranks it as “moderate,” “above average,” or

“high.”

Dallas CountyOphthalmic Goods Mfg.

East TexasSurgical Instrument Mfg.

North Central RegionMedical Equipment Mfg.

Capital RegionSurgical Appliance Mfg.

Medical Devices &

Supplies

Manufacturing

Concho ValleyMedical Supplies Mfg.

Alamo RegionMedical Supplies Mfg.

Moderate

Above Average

High

Concentration

Data: Texas Workforce Commission

Workforce Concentrations

Heart of TexasMedical Supplies Mfg.

Medical Device Firm Relocates Headquarters from New York to Texas

In May 2012, medical equipment company

Greatbatch, Inc. announced plans to relocate its

corporate headquarters from Clarence, New York,to Frisco, Texas. Its Greatbatch Medical division

develops and manufactures critical device tech-

nologies for the cardiac, neurology, vascular and

orthopedic markets. Its Eletrochem Solutions

segment designs and manufactures battery and

wireless sensing technologies for industries includ-

ing medical devices.

Publicly traded Greatbatch relocated to Texas for its

vibrant medical device community, strong business

climate, and central U.S. location.

MEDICAL DEVICES

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MEDICAL DEVICES

Texas Medical Device Clusters

Orthopedics

Cardiology

Key Products: Spinal, extremity, bone/tissue

implants

Key Companies: The Austin region is home to more

than 15 spinal and extremity orthopedic firms,

originally anchored by the spine division of Fortune

1000 device maker Zimmer. Other orthopedic

leaders in the region include DJO Surgi-

cal, Hanger Orthopedic, and Integra

LifeSciences. Additonally, multiple bone

and tissue grafting firms, including

Zimmer Orthobiologies and BME, are

located in the Austin-San Antonio

corridor. Further north, the Dallas/Fort

Worth region is home to the U.S. HQ of

Dutch orthopedic firm OrthoFix.

Key Products: Catheters, surgical instruments,

prosthetic heart valves

Key Companies: The Houston metro area is a hub of

cardiology R&D and startups and is the location of

established cardiovascular device firms like Merit

Medical Systems and Cardiovascular Systems, both

located in the suburb of Pearland. In the Dallas/Fort

Worth region, Allen-based Atrion Corp.and Plano-based Argon Medical Devices

manufacture instruments for cardiovas-

cular surgery. In Austin, prosthetic heart-

valve manufacturer On-X Life Technolo-

gies is part of that metro area’s growing

cardiology sector.

Diagnostics

Key Products: Cell cultures, laboratory equipment,

clinical chemicals

Key Companies: Austin is home to a cluster of

cutting edge diagnostics equipment firms, including

Luminex, Agilent Technologies, Asuragen, and

Thermo Fisher Scientific, while the nearby San

Antonio’s diagnostics cluster is anchored by Becton

Dickinson’s corporate service center and Fujirebio

Diagnostics’ facility in Seguin. TheHouston and Dallas/Fort Worth

regions are also home to major

diagnostic product makers, including

Fortune 500 giants Thermo Fisher

Scientific in Houston and Abbott

Laboratories in Irving.

Wound Care

Key Products: Electromedical wound equipment,

mattress systems, skin dressings, bandages

Key Companies: Dallas/Fort Worth’s concentration

of wound care firms is lead by Healthpoint

Biotherapeutics, a maker of treatments for acute,

chronic, and burn-related wounds. Medical supply

firms in the region include wound-dressing makers

Strukmyer, Winfield Laboratories, and

Ferris Manufacturing. San Antonio is

also home to an established wound

care cluster, which includes Kinetic

Concepts, Inc. (KCI) and Innovative

Trauma Care (ITC), and wound and

burn R&D organizations Rochal

Industries and the National Trauma

Institute (NTI).

9



MEDICAL DEVICES

Representative sample only. Sources: Dun & Bradstreet, company websites

Major Companies

Top 10 Medical Device & Equipment Companies with Texas Operations

By Parent Company Global Revenues Company Name

Primary

Locations Specialization

Sales

(Millions)

Ethicon (Johnson & Johnson) San Angelo Surgical supplies $67,224

Alcon Research (Novartis) Houston Ophthalmic products $57,561

Abbott Laboratories Irving Diagnostics $39,874

Flextronics Irving, Plano Contract design & manufacturing $29,387

Medtronic Fort Worth, Surgical devices & diabetes mgmt. $16,184

Thermo Fisher Scientific Austin Diagnostics $12,509

Stryker Communications Flower Mound Operating room equipment $8,657

Becton Dickinson & Co. San Antonio Diagnostics, drug delivery $7,708

Agilent Technologies Cedar Creek (Austin) Diagnostics $6,615

St. Jude Medical Plano Neurology $5,858

Texas Focuses on Eye Care Products Manufacturing

Texas is home to a large cluster of ophthalmic goodsmanufacturers that produce eye care devices andmedical supplies. The percentage of the Texasworkforce employed in the ophthalmic goods sector is

20% higher than the national average, and theseworkers are particularly concentrated in the Dallas/Fort Worth region. Leading firms in this cluster arehighlighted below.

Fort Worth & Houston — Lens care

products and surgical disposables

Bedford— Contact lenses

Dallas — Contact lenses and lens

coatings

Garland — Lens processing supplies,

such as tints and anti-reflective coats

Rosenberg — Optical tools, surgical

supplies, and contact lens accessories

Lewisville — Eyeglass lenses

Allen — Contact lens

disinfection cases, and ophthal-

mic balloon catheters

Waco — Lens

care products

10



Agrowing list of global pharma companies

have established research and production

facilities in Texas, including California-based

Allergan, Pennsylvania-based Mylan, and

Switzerland’s Lonza. Additionally, Texas has also

fostered the headquarters of homegrown

pharmaceutical successes like Fort Worth’s

ophthalmic leader Alcon (now part of Novartis) and

wound care innovator Healthpoint Biotherapeutics

(now part of Smith and Nephew). These companies

and many others have developed a substantial

pharmaceutical manufacturing workforce in the state.

Approximately 120 firms now employ more than

10,000 workers in the sector, and as a result, Texas is

one of the top 10 states in the nation for number of

pharmaceutical manufacturing workers.

In 2011, the total value of

T e x a s p h a r m a c e u t i c a l

shipments approached $4.8

billion, with manufacturers

m a k i n g t o t a l c a p i t a l

investments of over $80

million, according to the U.S. Census Bureau.

Texas is also a leading pharmaceutical research state.

In March 2013, Texas ranked second nationally for

number of clinical trials, with more than 15,000

studies underway, according to the National Institutes

of Health (see map below). In addition, many of the

world’s leading clinical trial and contract research

firms have operations across Texas, including PPD,

Covance, Quintiles, INC Research, inVentiv Health

Clinical, and Radiant Research.

Source: NIH ClinicalTrials.gov

Clinical Trials by State, March 2013

Texas ranks

No. 2

Pharmaceuticals

Texas pharmaceuticalcompanies employmore than 10,000

skilled workers

11



Pharmaceutical

& Medicine

Manufacturing

Capital RegionBiological Product Mfg.

Consumable Pharmaceuticals Mfg.

Tarrant CountyConsumable Pharmaceuticals Mfg.

Alamo RegionConsumable Pharmaceuticals Mfg.

Moderate

Above Average

High

Concentration

Data: Texas Workforce Commission

The map below identifies the state’s Workforce

Development regions with above-average specializa-

tions in pharmaceutical manufacturing. The high-

lighted regions are not the only areas in Texas where

workers in this sector can be found, but rather repre-

sent areas with the greatest concentrations

relative to the size of the local labor force. This

analysis compares the portion of each Texas region’s

workforce employed in the sector to the portion of the

entire U.S. workforce employed in that sector. The

comparison provides a ratio that measures how inten-

sively a certain region is specialized in this industry,

and ranks it as “moderate,” “above average,” or

“high.”

Workforce Concentrations

In early 2012, Alcon Laboratories, a subsidiary of Swiss pharmaceutical

giant Novartis, began a $15 million expansion to its R&D and corporate

headquarters operations in Fort Worth, Texas. The project includes

upgrades to the company’s existing facilities as well as construction of anew financial service center. Alcon, which has been based in Fort Worth

since its founding in 1945, develops and manufacturers surgical

equipment, pharmaceuticals, and vision care products. Parent company

Novartis purchased Alcon in 2010 to expand its ophthalmic product

offerings. At the time of the purchase, Alcon was the world’s largest

independent eye care products company.

Novartis Eye Care Subsidiary Expands in Fort Worth

PHARMACEUTICALS

Alcon’s Fort Worth campus

12



Company Name Primary

Location Specialization

Sales

(Millions)

Alcon (Novartis) Fort Worth Ophthalmics $57,561

Colgate Oral Pharmaceuticals Dallas Dental care $17,085

Mylan Sugar Land Generic Pharmaceuticals $6,796

Allergan Waco Ophthalmics $5,806

Healthpoint Biotherapeutics Fort Worth Dermatology $4,270

Lonza Houston Houston Viral vectors $2,864

PPD Austin Pharmaceutical R&D $1,470

Galderma Laboratories Fort Worth Dermatology $1,401

Virbac Corp. Fort Worth Veterinary care $807

ALK-Abello Round Rock Allergies $409

Representative sample only. Sources: Dun & Bradstreet, company websites

Top 10 Pharmaceutical Companies with Operations in Texas

by Parent Company Global Revenues

PHARMACEUTICALS

Major Companies

In 2012, Fort Worth-based DFB Pharmaceuticals,

a fully integrated specialty pharmaceutical

company, streamlined its operations through two

major sales.

DFB sold a majority stake in its contract manufac-

turing unit, San Antonio-based DPT Laboratories,

to Illinois-based Rennaisance Acquisitions

Holdings. DPT remains in Texas and DFB

maintains a meaningful interest. DFB also sold its

Fort Worth-based Healthpoint Biotherapeutics

subsidiary to UK-based medical technology giantSmith & Nephew (S&N). Healthpoint

remains in Texas and has become

part of S&N’s advanced wound

management division.

Fort Worth’s DFB Pharmaceuticals Sells

Healthpoint and DPT UnitsSpecialty pharmaceuticals giant Allergan

continues to expand its Waco, Texas, manufactur-

ing facility. The company has invested over $30

million in improvements over the past five years

and plans to hire 100

in the Waco area by

2017.

Allergan first located its manufacturing plant in

Waco and began producing eye care products in

1989. The facility’s 2003 expansion consolidated

the company’s North American manufacturing

operations, and the Waco plant’s product linenow includes skin care products for acne and

psoriasis.

California-based Allergan is a Fortune 500

company with a diverse array of pharmaceutical,

biological, and medical device products.

Allergan Expanding in Waco

13



MirVana miRNA

isolation kit

Texas Startup ZS Pharma Raises $46 Million in Funding

In October 2012, Fort Worth-based ZS Pharma, a

Texas Emerging Technology Fund (TETF) awardee,announced that it had raised $46 million to assist its

commercialization efforts. The company plans to

conduct clinical trials on ZS-9, a crystal form of

zirconium silicate, designed to treat patients with

kidney and liver disease.

The TETF invested $2 million in ZS Pharma in

August 2010 to assist the commercialization of its

therapeutic solution for complications associated

with liver and kidney failure. The company hasfurther plans to research and develop other

compounds to address the same problems, for

which there are limited treatment options.

PHARMACEUTICALS

Texas-Made Pharmaceutical Products

Allclenz and Curasol

wound care products

Pediatric pharmaceutical productsTRAVATAN

glaucoma treatmentsRefresh eye care products

Colgate oral pain relief products

Opti-Free

14

A wide variety of consumable pharmaceuticals and

pharmaceutical products are manufactured in

Texas. Below are a few examples of leading prod-

ucts, ranging from Alcon and Allergan’s eye care

products to Pernix’s pediatric products.



PHARMACEUTICALS

Advanced Pharmaceutical Clusters in Texas

15

Biodefense & Pandemic PreparednessBiodefense technologies are designed to inoculate

citizens against infectious agents that may be used

in an attack and to detect biological, chemical, or

nuclear attacks. In addition, technologies can make

urgently needed treatments easier to administer on

the battlefield or during a civilian crisis.

Key Texas Research Centers: The University of Texas

Medical Branch (UTMB) Center for Biodefense and

Emerging Infectious Diseases houses a Biosafety

Level-4 lab in Galveston, as does the privately run

Texas Biomedical Research Institute in San Antonio.Texas A&M’s Center of Innovation in Advanced

Development and Manufacturing (CIADM) in

College Station serves as one of three federally

designated biodefense centers.

Key Companies: In Houston, 1st Detect designs

products to detect chemical warfare agents and

explosives, while

Pulmotect,

develops therapies

to boost human

immune systems

against bioterror

agents like anthrax

that attack the

lungs. Austin-

based Inview

Technology’s

cameras operate

the short wave infrared spectra beyond human

visibility for applications ranging from military and

defense to microscopy and life sciences. Bryan-

based G-CON makes self-contained clean room

pods that can be used for drug development and

biomanufacturing.

Vaccines

Vaccines improve the body’s resistance to disease

by introducing weakened forms of a disease-causing

organism. Researchers are continuing to discover

new applications for vaccines, as well as methods to

improve production capabilities and delivery

systems.

Key Texas Research Centers: Texas A&M’s National

Center for Therapeutics Manufacturing (NCTM) and

CIADM, two new facilities soon to be national

leaders in vaccine development and manufacturing.

UT San Antonio’s South Texas Center for Emerging

Diseases, focused on vaccine development andinfectious diseases.

Key Companies: In Houston, Texas Emerging

Technology Fund awardee Bellicum Pharmaceuti-

cals is developing oncological therapies, including a

vaccine for prostate cancer, while Austin-based

Astrogenetix uses biomarkers developed in the

microgravity of

space to develop

vaccines for

salmonella.

Globally headquar-

tered in Denmark,

pharmaceutical

company ALK

Abello has its U.S.

headquarters in

the Austin suburb

of Round Rock and

is a leader in the

development of

allergy vaccinations, which are designed to reduce

and potentially eliminate the effects of an allergic

reaction.



PHARMACEUTICALS

16

Personalized Medicine

Personalized medicine uses individual geneticinformation to prevent disease, choose medicines,

and make other decisions about health. Researchers

are interested in the use of gene-based tests to

match patients with optimal drugs and dosages.

Key Texas Research Centers: The University of Texas

M.D. Anderson Cancer Center’s Sheikh Khalifa Bin

Zayed Al Nahyan Institute for Personalized Cancer

Therapy (IPCT), located in Houston, is a leader in

the field. The Texas A&M Institute for Genomic

Medicine (TIGM), with the world’s largest library of

mouse knockout embryonic stem cells, is advancing

personal medicine at the genomic level.

Key Companies: Austin houses a cluster of personal-

ized medical companies including Asuragen, an

Ambion spinoff and leader in personalized molecu-

lar diagnostics; Luminex, which offers a wide range

of diagnostics and research assays throughout the

areas of infectious diseases, human genetics, andpersonalized Medicine; and NanoMedical Systems,

which is developing its implantable Personalized

Molecular Drug-

delivery System to

improve the long-

term release of

therapeutic

agents. Dallas-

based Caris Life

Sciences is a

leading provider of

pathology tech-

nologies and offers

customized

molecular profiles

of patient tumors to facilitate effective treatments.

Regenerative Medicine

Research institutions are gaining the capability tocreate personalized organs in the laboratory that

match a patient’s specific genetic makeup, relieving

the pressure of finding a donor.

Key Texas Research Centers: Texas A&M’s Health

Science Center’s Institute for Regenerative Medi-

cine is an A&M joint venture with Scott & White

Hospital and the Temple Bioscience District that

received $5 million in TETF funding. Baylor College

of Medicine’s Stem Cells and Regenerative Medi-

cine (STaR) Center focuses on stem-cell stimulation

to regenerate tissues and the use of stem cells to

repair damaged tissue. The Armed Forces Instituteof Regenerative Medicine (AFIRM) at Fort Sam

Houston in San Antonio advances therapies for

injured veterans and service members.

Key Companies: Austin-based SpineSmith designs,

develops, and markets implants and biologics forsurgical fixation, correction, and tissue regeneration

of the spine. Spine-

Smith subsidiary

Celling Biosciences,

also Austin-based,

develops tissue

regeneration thera-

pies utilizing adult

stem cells, focusing

its R&D on the areas

of orthopedics,

cardiovascular

systems, trauma,

plastics, and diseases.

San Antonio area-based America Stem Cell and

College Station-based BLAST Therapeutics are

developing technologies to expand the therapeutic

potential of bone marrow-derived stem cells.



Research and development (R&D) is the

lifeblood of the biotechnology industry. In

Texas, the R&D pipeline is supplied in part by

the state’s vast network of public universities and

health-related institutions, which invest heavily in

R&D and intellectual property generation. In fiscal

year 2012 alone, Texas public institutions of higher

education expended almost $2.6 billion on medical

and life sciences research, accounting for over 60% of

all higher education R&D expenditures in the state.

Public investment in biotechnology research is

complemented by the state’s substantial cluster of

private sector R&D activity. Texas is home to over

920 private scientific R&D firms that employ more

than 20,400 workers. Many of

the largest private biotechnology

R&D firms in the world have

operations in Texas, including

PPD, Covance, Quintiles, INC

Research, inVentiv Health

C l i n i c a l , a nd R a d i a n t

Research. These firms have helped make the state a

hub of clinical trials and other breakthrough research.

In the Austin and San Antonio regions, the percentage

of the workforce employed in private-sector scientific

R&D is more than 30% above the national average,

while in the Houston area, the percentage of the

workforce employed by specialty hospitals is more

than four times the national average.

In addition to R&D facilities, Texas has more than

1,500 medical and testing laboratories, which include

blood, pathology, imaging, diagnostics, and device

testing facilities. These laboratories employ more

than 33,600 in Texas. Major laboratory firms in the

state include LabCorp’s Esoterix subsidiary and

Spanish biological product firm Grifols.

Biomedical Research

Texas is also a leader in cancer research. Major

institutions in this field include MD Anderson

Cancer Center in Houston, Scott & White

Healthcare Cancer Research Institute in Temple,

and Texas Oncology and Mary Crowley Cancer

Research Centers, both based in Dallas.

Additionally, the Cancer Prevention and Research

Institute of Texas (CPRIT), a state-funded initiative,

has been instrumental in expanding Texas cancer

research.

In 2011 the National Science Foundation ranked

Texas among the top tier of U.S. states for

number of doctorates awarded in biotech-related

fields:

for All Doctorates Awarded

for Agricultural Sciences/Natural

Resources Doctorates

for Health Sciences Doctorates

for Life Sciences Doctoratesfor Biological Sciences Doctorates

Texas in Top Tier for

Biotech-Related Doctorates

in 2012, Texaspublic institutionsexpended $2.6billion on lifescience R&D

#2

#3

#3#3

#3

17



OVERVIEW

Biotech Education in Texas

Source: Texas Higher Education Coordinating Board

Number of Biotechnology-Related Degrees Awarded, 2009-2012

All Texas Public Universities, All Degree Levels

Biological and Biomedical Sciences

Healthcare Professionals and Technicians

Plant and Agricultural Sciences

26,084

14,413

6,842

Top Ten Texas Public Institutions

for Biomedical R&Dby FY 2012 Expenditures

InstitutionTotal R&D

(Millions)

Univ. of Texas (UT) M.D. Anderson Cancer $582.1

Baylor College of Medicine-Houston $450.6

UT Southwestern Medical Ctr. at Dallas $389

UT Health Science Center at Houston $226.7

UT Health Science Center at San Antonio $163.8

UT Medical Branch (UTMB) at Galveston $139.3

Texas A&M Health Science Center $77.5

Texas Tech University Health Science Ctr. $60.6

Univ. of North Texas Health Science Ctr. $42

UT Health Science Center at Tyler $12

TOTAL $2,143.6

Source: Texas Higher Education Coordinating Board

Animal Sciences 3,318

50,657TOTAL

BIOMEDICAL RESEARCH

In 2012, the University of Texas (UT) ranked No. 2 nationally for the number of pharmaceutical-related

patents earned by a university (Class 424—Drug, Bio-Affecting and Body Treating Compositions),

behind only the University of California, according to the U.S. Patent and Trademark Office.

Texas Places Five Research

Medical Schools in Top 100

In 2012, U.S. News & World Report

ranked the nation’s top 100 research

medical schools. Texas landed five

schools on the list:

#83

Texas A&MHealth Science

Center

#67UT

Health ScienceCenter at

San Antonio

#55UT

Health ScienceCenter at Houston

#21

Baylor Collegeof Medicine

#20UT

SouthwesternMedical Center atDallas

18



2005 military base realignments across the nation,

which consolidated military medical facilities in San

Antonio. A sampling of military, university, and

private medical research facilities are profiled

regionally on the following pages. The map below

provides a broad snapshot of some of the state’s

major medical-related research centers and nine

medical schools.

Texas is home to top-ranked biotechnology and

medical research institutions, federally designated

centers, innovative research collaborations, and some

of the world’s largest medical complexes. A number

of the most ambitious Texas medical center expansions

are a result of the U.S. Department of Defense’s (DoD)

Due to space limitations, not all institutions are included.

BIOMEDICAL RESEARCH

Research Centers

Texas Medical Schools & Selected Medical Research Centers

19



BIOMEDICAL RESEARCH

The Texas Medical Center (TMC) in Houston is the

world’s largest medical center with over 71,500

students and 92,500 employees, housed on 1,300

acres.

The TMC has a total budget of $14 billion encom-

passing its 54 member institutions, comprised of

hospitals, schools, and other specialty institutions,

include Baylor College of Medicine, UT M.D.

Anderson Cancer Center (MDACC), UT Health

Science Center, the University of Houston (UH),

Rice University, Texas A&M University Health

Science Center, The Methodist Hospital, and Texas

Children’s Hospital.

The TMC plans $7.1 billion in capital investment

through 2014, including the $1

billion Baylor Clinic and Hospi-

tal. In 2012, TMC member

MDACC began a $198 millionhospital renovation and expan-

sion project that will add

185,000 sq. ft. by 2016.

In 2012, the TMC added four

new members: DePelchin’s

Children’s Center; The Men-

ninger Clinic; Sabin Vaccine

Institute; and UH Victoria School

of Nursing.

World’s Largest Medical Center Keeps Growing in Houston

Texas MedicalCenter Complex

Downtown Houston

UTHealth Ranks 7th Largest

Medical School in the Nation

Located in Houston’s TMC, the University of Texas

Health Science Center at Houston (UTHealth) is

the largest of the state’s nine medical schools and

focuses primarily on graduate education and re-

search.

Has over 10,000 faculty,

staff, students, and residents, andeducates more healthcare profes-

sionals than any other Texas

institution

Conferred more than 1,270 degrees and spent

almost $261.2 million for research in FY 2011

BCM Top Ranked for R&D

The Baylor College of Medicine

(BCM) in Houston, located in

Houston’s TMC, is the state’s

only private medical school.

Has research support of

$363 million and trains over 3,000 students,

including residents and post-doctoral

Ranked as one the nation’s top 25 medicalschools for research by U.S. News & World

Report in 2013

Ranked 2nd nationally in federal funding for

R&D in the biological sciences at universities

by the NSF in FY 2010

HOUSTON/GULF COAST

20



BIOMEDICAL RESEARCH

UTMB at Galveston Fights Infectious Diseases

The University of Texas Medical Branch (UTMB) at Galveston was estab-

lished in 1891, making it the oldest of UT Systems’ four medical schools.UTMB has developed a strong program in infectious disease research

with several facilities devoted to that field.

Has over 10,600 faculty, staff, and students,

with total research expenditures of $126.9

million in FY 2012

Became a member of Houston’s Texas Medical

Center in 2010

Serves as one of the nation’s 11 federal

Regional Centers of Excellence for Biodefense

and Emerging Infectious Diseases Research

(CBEID), for the Western Region. The CBEID atUTMB Galveston was established by the

National Institutes of Health (NIH) in 2002.

The CBEID serves as the lead institution for

participating academic institutions in the

Western Region, a five-state area that includes

Louisiana, Arkansas, New Mexico, and

Oklahoma.

One of the nation’s two National

Biocontainment Laboratories is located at

UTMB. The Galveston National Laboratory

(GNL) was established with grants awarded by

the NIH’s National Institute of Allergy and

Infectious Diseases (NIAID). The GNL conducts

research to develop therapies, vaccines, and

diagnostic tests for naturally occurring emerging

diseases such as SARS, West Nile encephalitis,

and avian flu, as well as for microbes that mightbe employed by terrorists.

In 2003, the UTMB CBEID was awarded a $110

million NIH grant to establish the Robert E.

Shope Laboratory, a Biosafety Level 4 facility.

The lab opened in 2004 and is the first full-sized

facility of its kind in the nation to be located on a

university campus.

M.D. Anderson Announces Moon Shot

to Cure Cancer

In September 2012, UT M.D. Anderson (MDACC),

located at Houston’s TMC, announced the launch

of its $3 billion Moon Shots Program, an unprece-

dented effort to accelerate the commercialization

of scientific discoveries to reduce cancer deaths.

The program’s name is inspired by America’s space

program to put a man on

the moon.

Initially, MCACC’s program

will target the followingcancers: leukemia, lung,

melanoma, prostate, and

triple-negative breast and

ovarian.

The Methodist Hospital System

Expands Research Arm

Since 2004, the Methodist Hospital Research

Institute (MHRI) has overseen interdisciplinary

scientific activity for The

Methodist Hospital System.

The MHRI is a TMC member

with $100 million in annual

research expenditures and

over 1,300 researchers. The

institute’s NIH research

funding doubled from 2011 to 2012.

In May 2011, MHRI announced the recruitment of renowned cancer geneticists Dr. Nancy Jenkins

and Dr. Neal Copeland, with the help of funding

from the state cancer initiative, CPRIT. In 2010, the

Institute opened a new 440,000 sq. ft. facility

solely dedicated to research.

21



BIOMEDICAL RESEARCH

NORTH TEXAS

University of North Texas Leads Osteopathic Research

The Texas College of Osteopathic Medicine (TCOM)

is located at the University of North Texas HSC in

Fort Worth. It is the state’s only osteopathic medical

school.

Has over 1,385 students and faculty members

Approximately 65% of TCOM's graduates

practice primary care medicine, helping reduce

the state and nationwide shortage

Ranked as one of the nation's top 50 medical

schools for primary

care by U.S. News &

World Report

TCOM’s Osteopathic

Research Center is a

national research program that studies the

clinical effectiveness of osteopathic manipulat-

ive medicine

Southwestern Medical District Expansions

The Southwestern Medical District (SMD) in

Dallas is a 390-acre medical complex that is home

to world-class biomedical

research organizations employ-

ing nearly 27,000. Member

institutions include University

Hospital-St.Paul, University

Hospital-Zale Lipshy, Children’s

Medical Center Dallas, and

Parkland Health & Hospital

System. Planned SMD expan-

sions include new Parkland

hospital facilities, a new $800

million state-of-the-art Univer-

sity Hospital, and a Children’s

Medical Research Institute.

One of the world’s top aca-

demic medical centers, the

University of Texas Southwest-

ern Medical Center (UTSWMC),

is also located at SMD. UTSWMC alone employs

about 11,400 and trains nearly 4,600 students

annually.

Ranked No. 20 for

best U.S. research

medical schools in 2013 by U.S. News & World

Report

Its Harold C. Simmons Cancer Center is a Na-

tional Cancer Institute designated cancer center,

a distinction held by only the top-tier cancer

centers nationwide

UTSWMC outstanding faculty has included five

Nobel Prize recipients since 1985

22



BIOMEDICAL RESEARCH

SOUTH TEXAS

UTHSC at San Antonio Spurs Local

Biotech Industry

The University of Texas Health Science Center

(UTHSC) at San Antonio is one of the UT Sys-

tem’s four medical

schools.

Over 4,400

students enrolled on

eight campuses in San

Antonio, Harlingen,

Edinburg, and LaredoManaged $193 million in annual research

related activities in FY 2012

Opened the new $150 million South Texas

Research Facility in late 2011. The 188,000

sq. ft. building will house up to 20 lab teams,

working in areas ranging from regenerative

medicine to cancer research.

Military Medical System Grows in

San Antonio

In September 2011, U.S. Air Force and Army

officials activated the San Antonio Military

Health System (SAMHS), which provides

oversight for all

military treatment

facilities and the

healthcare needs of

approximately

230,000 DoD benefici-

aries in the San

Antonio area.

Managing a $839

million budget, SAMHS healthcare services are

provided by the San Antonio Military Medical

Center (SAMMC), a Level 1 trauma center and

the DoD’s largest inpatient hospital; Wilford

Hall Ambulatory Surgical Center (WHASC),

which is the DoD’s largest outpatient ambula-

tory surgery center; 19 primary care clinics; and

over 100 specialty services.

San Antonio Thrives as Hub of Private Sector Scientific R&D

Since 1947, San Antonio’s Southwest Research

Institute (SwRI) has provided contract R&D

services to industrial

and government

clients across indus-

tries, which today

include biotechnology

and medicine. SwRI’s headquarters facility

employs nearly 3,000 workers and occupies over

two million square feet of office and laboratory

space across 1,200 acres. SwRI’s 2012 revenues

exceeded $584 million and, in 2012, the organiza-tion dedicated $7.4 million to fund its internal

research programs separate from contract client

projects.

The Texas Biomedical Research Institute, SwRI’s

sister institution located on an adjacent 200 acre

campus, is one of the world’s leading independent

biomedical research institutions. Texas Biomed has

a nearly $55 million annual budget and employs

approximately 400 people. The institute is home to

the Southwest National Primate Research Center

and the world’s largest colony of baboons for

biomedical research; the nation’s only privately

owned biosafety level

4 laboratory; and the

AT&T Genomics

Computing Center, the

world's largest com-puter cluster devoted

to human genetic and

genomic research.

23



BIOMEDICAL RESEARCH

CENTRAL TEXAS

A&M National Center for Therapeutics Manufacturing Leads Biodefense

The Texas A&M University’s National

Center for Therapeutics Manufacturing

(NCTM) is a first-in-class biopharmaceu-

tical GMP (Good Manufacturing Practice) manufac-

turing facility and interactive academic training

center. Opened in 2012, the NCTM was built in

collaboration with UT’s M.D. Anderson Cancer

Center (MDACC) as part of a major joint research

initiative on cancer announced in May 2010

between NCTM and MDACC. A $50 million TETF

award in 2009 also helped establish the NCTM.

With over 150,000 sq. ft. of space for biophar-

maceutical manufacturing, advanced develop-

ment, and training, the NCTM is now an

important part of one of the nation’s three

UT Austin Biotech Institutions

The University of Texas at Austin (UT Austin) is one

of the nation’s largest universities and one of Texas’three Tier One research universities. UT Austin has a

number of biotechnology-related divisions, institutes,

and centers. Selections are highlighted below.

The DDI was established in 1974 as a multi-

disciplinary research center where scientists,

educators, businesses

a n d r e g u l a t o r y

specialists collaborate

in finding solutions to a

wide range of

biomedical, pharma-

ceutical, and public

health issues.

Established in 1993, the ICMB is a multidiscipli-

nary center of excellence for biotechnology

whose goal is to promote cell

and molecular biology research

and education. The Institute

conducts fundamental research

into the basic processes of living

cells and tissues, which is crucial

to future advances in medicine

and biotechnology.

Opened in 2012, the IRC, previously known

as the Neuroscience Imaging Center, re-ceived a $3.5 million TETF award in 2007 to

establish a center to study cognitive brain

functions using Magnetic Resonance Imag-

ing (MRI) technology.

NCTM facility in College Station, Texas

biodefense centers, the TAMU Center for Innovation

in Advanced Development and Manufacturing.

24

http://www.irc.utexas.edu/

http://www.icmb.utexas.edu/



BIOMEDICAL RESEARCH

Biotech Collaborative in Bryan-College Station

In June 2011, the Texas A&M University System

(TAMU), in conjunction with The Research ValleyPartnership, unveiled the One Health PLUS™

Biocorridor, a master planned center in Bryan-

College Station, Texas for education, research, devel-

opment, com-

mercialization,

and the produc-

tion of biotech-

nology products

and therapies, including pharmaceuticals and vac-

cines.

Anchored by TAMU, one of the nation’s top research

institutions, the Biocorridor intends to become the

nation’s premier destination for the discovery of

new therapies, pre-clinical trials, and manufactur-ing—all in one location. The Biocorridor’s interdis-

ciplinary collaborations and research will encom-

pass humans, animals, and plants.

Participating Biocorridor research facilities include

the TAMU Health Science Center, the TAMU Col-

lege of Veterinary Medicine and Biomedical Sci-

ences (CVM), TAMU AgriLife, the Texas Engineering

Extension Service, the TAMU Institute for Preclini-

cal Studies (TIPS), TAMU Institute for Genomic

Medicine (TIGM), and TAMU’s National Center for

Therapeutics Manufacturing (NCTM).

Over the past ten years, the city of Temple has built a

unique health and bioscience industry cluster around

local academic, medical, and research facilities.

In 2003, the Temple Health & Bioscience District

(THBD) was created through unique state

legislation and the approval of local citizens.

The THBD’s Scott & White (S&W) Cancer

Research Institute (CRI) opened in 2005, as part

of a joint development agreement with S&W

and led by renowned cancer researcher Dr.

Arthur Frankel.

The Texas Bioscience Institute (TBI) opened in

2006 to prepare students to enter the biosci-

ence and medical industries.

The Institute was created with

funding from the U. S. Depart-

ment of Labor, the city of

Temple, and S&W.

In 2007, the expansion of

the TAMU HSC College of

Medicine brought a new campus and four-year

medical school to Temple and Scott & White

Memorial Hospital (SWMH).

In 2007, the State of Texas announced a $7.5

million TEF grant to SWMH to increase critical

research initiatives and generate nearly 1,500

jobs during the next decade.

In 2008, the city

of Temple joined

THDB and its

partners topromote rede-

velopment plans

for a Temple

Medical & Education District (TMED).

In 2009, the State of Texas announced a $5

million TETF grant to recruit leading scientist Dr.

Darwin Prockop as the founding director of

TAMU HSC College of Medicine’s Institute for

Regenerative Medicine at S&W. The Institute

uses adult stem cells to develop new therapies.

In 2010, the Temple Bioscience Accelerator was

created to develop new bioscience companies inthe region.

In 2011, the THBD approved funding the THBD

Scholars Research Program, with cash awards

going to outstanding undergraduate students to

study and work in THBD facilities. The program

began sponsoring students in 2012.

Bioscience Research District in Temple

25



BIOMEDICAL RESEARCH

WEST TEXAS

EAST TEXAS

World-Class Pulmonary Research in East Texas

The University of Texas Health Science Center at

Tyler (UTHSCT) is a world-renowned center of

pulmonary and infectious disease treatment and

research.

Employs over 800 people, with more than 20

outpatient clinics, a hospital, and an emergency

care centerIts graduate medical education programs – with

residencies in family medicine and occupational

medicine – provide doctors for the Northeast

Texas region

Offers residency programs in family medicine

and occupational medicine, as

well as master’s degree

programs in biotechnology and

environmental science

Is the program sponsor of a

residency program in internal

medicine at Good ShepherdMedical Center in Longview

Partner to the Heartland National TB Center,

which is located at the Texas Center for

Infectious Disease in San Antonio and is one of

the nation’s four regional training and medical

consultation centers for tuberculosis.

El Paso Home toTexas’ Newest Medical School

The Paul L. Foster School of Medicine at Texas

Tech University Health Sciences Center at El Paso

(PLFSOM) opened in 2009, making it the state’s

newest medical school.

Has over 1,700 faculty and staff members

Is the only four-year medical school on the

U.S./Mexico border and operates a Border

Health Research program

Centers of Excellence in Cancer, InfectiousDiseases, and Neurosciences have received

funding from CPRIT and

the NIH

Partners include the

William Beaumont Army

Medical Center (WBAMC)

at Fort Bliss

TTUHSC Leads Medical Training

and Research in West Texas

The Texas Tech University Health SciencesCenter (TTUHSC) is based in Lubbock with

satellite campuses in Abilene, Amarillo, El Paso,

Lubbock, Odessa, and Dallas/Fort Worth.

TTHUSC system includes two medical

schools, two nursing schools, a pharmacy

school, a graduate

school of biomedi-

cal sciences, and a

school of allied

health sciences

Has trained over10,000 health professionals to date

TTHUSC’s Clinical Research Institute was

established in 2010 to conduct clinical,

epidemiological, and educational research.

Ongoing studies span the fields of aging,

cancer, reproduction, genetic diseases and

rural health

26



Animal biotechnology focuses on the genetic

improvement of domesticated animal species,including cloning, selective breeding, artifi-

cial insemination, and genetic engineering. Crop bio-

technology research is centered on increasing yields

by making plants stronger and more resistant to pests

and environmental stresses, as well as by developing

biopesticides, herbicides, and other crop protections.

Texas is a natural choice for agricultural biotechnol-

ogy business as the nation’s leading producer of cattle

and cotton and the No. 3 overall producer of agricul-

tural products, behind California and Iowa. The Lone

Star State is also home to world-class agricultural edu-

cation and research facilities, particularly through the

Texas A&M and Texas Tech University Systems, as

well as established agricultural feedstock and chemi-

cals manufacturing industries concentrated in theTexas Panhandle and Gulf Coast regions. In 2011,

3,000 — or approximately one out of every 12 U.S.

agricultural feedstock and chemicals industry employ-

ees — worked in Texas.

Texas is the nation’s No. 1 cotton

producer and 91% of the state’s cotton

crop is genetically modified.

-U.S. Dept. of Agriculture

Leading Texas Research Centers

Animal & Agricultural Biotech

Texas has been at the forefront of animal and agricul-tural research for over 100 years. For decades, Texas

A&M University has led the nation in graduating

more students in animal and agricultural-related fields

than any U.S. institution. Below are profiles of some

of the state’s leading public research centers for agri-

cultural and animal sciences.

Texas A&M AgriLife Research

Established in 1887, AgriLife Research is the state’s

premiere R&D agency in agriculture, natural re-

sources, and the life sciences. It has a statewide pres-ence with 13 regional centers, over $190 million in

research funding, 550 doctoral-level researchers, and

approximately 580 annual projects.

Texas Tech Univ., Animal & Food Sciences

Dept., Burnett Center for Beef Cattle Research

Since 1984, Burnett Center scientists have contributed

extensively to human knowledge of beef cattle feeding

and management. Major research areas include animal

growth and composition, beef cattle nutrition, and the

environmental sustainability of cattle production.

Texas A&M, College of Veterinary Medicine

and Biomedical Sciences

Operating over 90 years, the college focuses a number

of disciplines including infectious diseases, toxicology

and environmental health science, cardiovascular sci-

ences, neurosciences, and reproductive biology. The

college is one of only 31 colleges of veterinary medi-

cine in the U.S. and Canada.

Texas A&M, Dept. of Soil and Crop Sciences

The department is the largest such facility in the worldwith a global reputation. It works to develop technolo-

gies to sustain environmentally sound and economi-

cally profitable production systems as well as to pro-

mote the wise use and management of soil, plant, and

water resources.

27



AGRICULTURAL & AGRI

Texas Tech Leads in Cotton Agricultural Genomics R&D

In February 2006, the Texas Emerging Technology

Fund (TETF) announced a $1.9 million investment

in Texas Tech University to help support a new

cotton genomics center. The TETF award played a

key role in the university’s recruitment of Dr. Thea

Wilkins, one of the world’s premier cotton geneti-

cists. Dr. Wilkins currently serves as Director of the

Center for Excellence of

Agricultural Genomics andBiometrics at TTU’s Depart-

ment of Plant and Soil Science

(DPSS) and has generated

millions of dollars in competi-

tive research funding from the

National Science Foundation, the U.S. Department

of Energy, and the USDA since 2006.

In August 2009, Texas Tech and Bayer CropScience

signed an exclusive licensing agreement for CFGC’s

new cotton technology. In May 2010, Bayer an-

nounced a $7.5 million contribution to TTU’s DPSS

to support new research initiatives and facilities

development. Through the 100%grant matching Texas Research

Incentive Program, this repre-

sents a $15 million total contri-

bution to TTU.

AGRICULTURAL & ANIMAL BIOTECH

Monsanto, however, is not the only global agricul-

tural biotech firm in Lubbock. Since 1998, German

conglomerate Bayer has operated its CropScience

division’s cotton research headquarters in Lubbock.

The site focuses on providing cotton growers with

products to meet

global demand for

cotton fiber. The

company maintains

a state-of-the-art R&D lab, two breeding stations, a

seed processing plant, a seed warehousing facility,

and supports two of its global cotton seed brands,

Stoneville and FiberMax, in Lubbock.

Both Monsanto and Bayer CropScience have

developed cotton R&D partnerships with Texas

universities, including two of the state’s leading

research institutions, Texas Tech University and

Texas A&M University. Monsanto offers technol-

ogy internships to TTU students, and, in 2009,

donated 4,000 cotton molecular markers and

associated information for R&D and breeding

purposes to TAMU AgriLife Research. Bayer

CropScience and TTU have been working together

to develop new cotton technology. See collabora-

tion details below.

Because Texas is the nation’s largest producer of

cotton, the state is a natural location for the R&D

operations of Fortune 500 agribusiness firm

Monsanto. In fact, the Missouri-based company

has nine locations in Texas, including a research

farm outside of Lubbock and testing centers in

Haskell and near Corpus Christi.

In December 2010, Monsanto opened its newest

Texas facility, the $10.5 million Texas Cotton

Breeding and Technology Center, in Lubbock.

Monsanto’s new

“research megasite”

exemplifies its

commitment to the

Texas cotton

industry and to

developing varieties

adapted to the

region, which

produces more

cotton than any other state.

“Cotton is big in Texas,” said Ted Crosbie, Vice

President for Global Plant Breeding at Monsanto.

“That’s why we built this megasite in Lubbock.

This will be our main cotton breeding center.”

Agribusiness Industry Leaders Invest in Texas Cotton R&D

Monsanto’s Cotton Breeding & Tech. Center

Dr. Thea Wilkins

28



Environmental biotechnology and biofuels are

transforming many industrial processes to

better conserve and sustain natural resources,

ensure food and water safety, utilize crop residues for

feed stocks and energy sources, and assist mature

industries such as food processing, public water

systems, and petrochemicals to become more competi-

tive. Biofuels and biomass are playing an increasingly

important role in Texas’ and the nation’s energy mix.

Renewable biofuels, including ethanol and biodiesel,

can be created from nonfood biomass such as algae,

lumber scrap, switchgrass, animal waste, and agricul-

tural residues like corn husks.

Building on the state’s strong agricultural and forestry

production base, Texas researchers and businesses are

investing in new renewable energy technologies to

maintain the state’s position as the nation’s energy

capital. Research in Texas ranges from exploring new

methods to convert nonfood stock materials to

investigating ways to turn algae into biofuels.

In FY 2011, Texas institutions of higher education

spent almost $223 million on environmental sciences

R&D, according to the Texas Higher Education

Coordinating Board. Additionally, the Texas Emerg-

ing Technology Fund (TETF) has invested over $23

million to date into environmental and biofuels-related

projects. See Appendix 1 for a complete listing.

Biofuels in Texas

Ethanol and biodiesel are alternative fuels defined by

their feedstock. Biodiesel can be produced fromvegetable or animal oils that are processed into an

alcohol ester, while ethanol can be produced from

corn and sugar cane, which are fermented and turned

into alcohol. Since Gov. Rick Perry laid out plans for

a statewide bioenergy initiative in 2007, Texas has

focused on developing alternative fuels from woody

grasses and other plants, rather than food crops like

corn.

As the nation’s No. 3 agricultural production state and

home to a large forest and cattle industry, Texas is

rich in biomass resources and well positioned as a

major biofuels producer. In 2012, Texas ranked No. 1

nationally with eleven biodiesel refineries providing

nearly 408 million gallons of annual production

capacity, according to the U.S. Energy Information

Administration. The majority of these biofuel manu-

Texas ranks No. 1 nationally for

biodiesel production-U.S. Energy Information Administration (EIA)

Environmental Tech & Biofuels

Texas is Home to the Nation’s

Largest Biodiesel Plant

Houston-based Renewable Biofuels, Inc. operates

the largest biodiesel plant in

North America, RBF Port Neches,

in Port Neches, Texas. Opened in

2008, the plant has a total refin-

ing capacity of 120 million gallons per year and ex-

perienced two years of record production in

2011 and 2012. The facil-

ity has expanded its per-

manent staff from 12 to

35 and now operates

24/7.

29



BIOFUELS

facturing facilities are located in the Houston, South-

east Texas, Dallas/Fort Worth, and West Texas

Panhandle regions.

The U.S. Department of Agriculture’s NationalInstitute of Food and Agriculture (NIFA) awards

research grants to support the development of sustain-

able bioenergy. In 2011 and 2012, the NIFA awarded

over $1.8 million in bioenergy grants in Texas for

separate studies at Texas A&M and Rice Universities.

Texas Biofuels Regulation

In 2011, the Texas Commission on Environmental

Quality (TCEQ) introduced new state guidelines

allowing biodiesel to be blended at any ratio into any

compliant fuel. This means former limitations, such asrequirements to use more additives within the bio-

diesel and producers having to report blending require-

ments, have ended. Texas biodiesel producers are now

exempt from paying the excise tax, even when the

biodiesel is blended with conventional diesel. The

TCEQ also authorizes state bioenergy facilities.

ENVIRONMENTAL BIOTECH & BIOFUELS

Texas Biorefinery Reopens

In October 2012, Iowa-based Renewable Energy

Group (REG) purchased an idled 15 million gallon/

year biorefinery near New Boston, Texas. The facil-

ity, 22 miles west of Texarkana,

was upgraded before resuming

operations in early 2013. REG

plans to create approximately 20

new jobs in Texas and to use ani-

mal fats and other fatty acid

feedstocks to increase its total production to over

225 million gallons annually. The New Boston plant

is REG’s second Texas biodiesel production facility,

following the 2008 purchase of a Houston-area

plant.

REG is one of the nation’s largest biodiesel produc-

ers and marketers with a nationwide distribution

and logistics system. Since 2008, REG has pur-

chased ten biodiesel-related firms or production

facilities, expanding the company’s footprint. The

company focuses on converting natural fats, oils,

and greases into advanced biofuels. No food crops

are used as feedstock.. REG’s premiere biodiesel

product, REG-9000® branded biodiesel, is distrib-

uted in nearly every state in the nation.

Housed at UT Austin, UTEX The Culture Collec-

tion of Algae (UTEX) maintains one of the world’s

largest algae collections, with nearly 2,800

strains. UTEX supplies algae strains globally for

research, biotech development, water quality

assessment, and a

variety of other

purposes.

UTEX is overseen by

Dr. Jerry Brand, a

professor in molecular

cell and developmental

biology at UT Austin.

UT Houses One of World’s LargestAlgae Collections

Dr. Jerry Brand

30



Company/ Entity

City Industry Segment Project Description Funding

(in Millions)

1st

Detect HoustonMedical Devices -

Biodefense

Portable chemical detector for security and medical

diagnostics$1.8

Admittance

TechnologiesAustin Medical Devices

Development of a monitoring device that can

monitor heart disease and detect heart failure$.5

Aegeria Medical

Devices (FKA Speer

Medical Devices)

San Antonio Medical DevicesNon-invasive continuous vital sign monitor for

pre-hospital use$2.5

America Stem Cell San Antonio BiopharmaceuticalsBone marrow stem cell transplant enzyme technol-

ogy for cancer and other disease treatment$1.25

Animal Innovations AmarilloVeterinary Medical

TechnologyAnimal injection technology $1

Apaxis Medical

(FKA SEMMT)Houston Medical Devices Left ventricular assist device (LVAD) implantation $.6

AuricX

PharmaceuticalsHouston Pharmaceuticals

Develop and commercialize a drug compound to

treat antibiotic resistant infections, like MRSA$1

Azaya Therapeutics San Antonio Biomedicine -Nanohealth

Azaya Liposome Encapsulated Radiation Therapy(ALERT) for cancer treatment

$1.045

Bellicum

PharmaceuticalsHouston

Biomedicine –Bio-

PharmaceuticalsCancer vaccine $1.45

Bio2 Medical San Antonio Medical Devices Temporary inferior vena cava filter catheter $1

Blue Box Health Houston Medical DevicesTechnology for home-health chronic disease man-

agement$1

Botaneco

(FKA AdviTech)

Formerly

San AntonioMedical Devices

Vision products to combat spatial disorientation,

vertigo & motion sickness$2.5

CardioSpectra San Antonio Medical Devices Fiber-optic cardiac catheter $1.35

Castle Biosciences FriendshipBiomedicine –

Medical DevicesBiomarker-based cancer detection system $1

Chipotle BusinessGroup

Arlington EnvironmentalHealth

Water safety testing $1

Corhythm San Antonio Medical Devices Implantable treatment for atrial fibrilliation $3.1

CorInnovaCollege

StationMedical Devices Heart therapy device $.5

Cormedics Houston Medical Devices Heart therapy device $.75

CryoPenCorpus

ChristiMedical Devices Cryosurgical device freezes unwanted tissue $2

DentLight Richardson Medical Devices Dental medical devices $.25

DEP Shape Memory

Therapeutics

College

Station

Medical Devices Cerebrovascular aneurism treatment $1

Diabetica Solutions

(FKA Xilas Medical)San Antonio Medical Devices Diabetic foot products $1

DNATriX Houston Biopharmaceuticals Genetically-modified virus for cancer therapy $.5

Endothelix Houston Medical Devices Cardiovascular test $1

Ensysce Biosciences HoustonBiomedicine -

NanohealthCarbon nanotube/siRNA cancer therapeutics $1.5

Appendix 1: Texas Emerging Technology FundAppendix 1: Texas Emerging Technology FundAppendix 1: Texas Emerging Technology Fund———Biotech AwardsBiotech AwardsBiotech Awards

31



Company/ Entity


(in Millions)

Environmental Quality

Management Associ-

ates (FKA EQMA)

Waco BiofuelsCAFOs (Concentrated Animal Feeding Operations)

feedstock to ethanol$.25

FE3 Medical San Antonio Medical Devices Trans-dermal drug patch to deliver iron for treatingiron-deficiency anemia

$2.8

Genprex Inc. (FKA

Convergen LifeSciences) Austin

Nanohealth – Bio-

PharmaceuticalsTargeted nanomolecular cancer therapies $4.5

Gradalis DallasBio-

PharmaceuticalsCancer therapeutics $1.75

Halsa Pharmaceuticals Houston Pharmaceuticals Clinical obesity drug development $1

InView Technology AustinFood Safety -

Biodefense

High-performance cameras that operate outside the

visual range (infrared, ultraviolet, and terahertz)$1.5

Laser Tissue Welding Humble Medical Devices Surgical therapy $.16

LaserGen Inc. Houston Biomedicine DNA sequencing technology $1

Leonardo BioSystems Houston

Biomedicine-

Nanohealth –

Medical Devices

siRNA cancer therapeutics $2.5

MacuCLEAR Plano Pharmaceuticals Optical therapeutics $1.7

MicroTransponder DallasMedical Devices -

NanohealthNeurostimulation Pain Management $1.38

MicroZAP Lubbock Food Safety Microwave food sterilization technology $1.5

Mirna Therapeutics AustinBio-

PharmaceuticalsMicroRNA therapeutics – cancer treatment $5

Molecular LogiXThe

Woodlands

Biomedicine – Bio-

PharmaceuticalsGenetically engineered therapeutic cancer treatment $.79

Monebo Austin Medical Devices Heart health assessment $.5

Mystic

PharmaceuticalsCedar Park

Pharmaceuticals-

Medical Devices

Specialty pharmaceuticals & ophthalmic and

intranasal drug delivery systems$1.56

Nano3D Biosciences HoustonNanohealth -

Medical Devices3-dimensional in vitro cell culturing $1

NanoMedical Systems

Inc.Austin

Medical Devices -

NanohealthPersonalized nanochannel drug delivery systems $3.5

NanoSpectra

BiosciencesHouston

Medical Devices -

NanohealthOncologic imaging detection using nanoparticles $1.25

National Trauma

Institute (NTI) San Antonio

Health Sciences –

Health Information

Technology

Civilian and military trauma research $3.8

Net.Orange IrvingHealth Information

TechnologyHeath care information management software $1.9

Neuro Resource

GroupPlano Medical Devices

Commercialization of InterX products technology for

post-operative acute pain management$1.5

Neurolink San Antonio Medical DevicesBrain implant system to monitor brain activity and

directly deliver drugs to treat brain seizures$3.2

Noninvasix Galveston Medical Devices Hemoglobin monitor $.25

TEXAS EMERGING TECHNOLOGY FUND

32



Company/

Entity City Industry Segment Project Description

Funding

(in Millions)

Oncolix Houston PharmaceuticalsDevelopment of a non-chemotherapy drug for

treatment of ovarian cancer$2.4

OnTrack Imaging FlowerMound

Veterinary Medical

Technology—

Medical Devices

Ultrasound imaging system for horses $1

Ortho Kinematics Austin Medical Services Spine function testing $1.5

OrthoAccel Houston Medical Devices Orthodontics $.75

Palmaz Scientific Dallas Medical Devices SESAME stent $3

Patton Surgical Austin Medical Devices Abdominal-based laparoscopic surgery $3

Photon8 Brownsville Biofuels Algae-based biodiesel fuel $1

PLx Pharma Houston Pharmaceuticals Non-steroidal Anti-Inflammatory Drugs (NSAIDs) $2

Procyrion Houston Medical DevicesDeveloping the first catheter-deployed circulatory

assist device intended for long-term use$.75

Pronucleotein

BiotechnologiesSan Antonio

Environmental

Health

Food and water safety testing products using DNA

aptamer sequences to detect pathogens$1

Pulmotect HoustonBiomedicine -

Biodefense

Stimulated Innate Resistance (StIR) against inhaled

pathogens$1

Quantum Logic

DevicesGeorgetown

Nanohealth –

Medical DevicesNanoelectronics medical diagnostic technology $.6

RadioMedix Houston Pharmaceuticals

Manufacturing radiopharmaceuticals to diagnose

and treat diseases, including cancer, through

positron emission tomography (PET)

$2.8

Receptor Logic Austin Biomedicine T-cell mimic receptors antibodies technology to treatcancer and other diseases

$2

Resonant Sensors ArlingtonMedical Devices -

NanohealthOptical biochemical sensors $.6

Salient

PharmaceuticalsHouston Pharmaceuticals

Treatment of cancer-related gastrointestinal side

effects caused by disease, chemotherapy, or radia-

tion

$2

Savara

PharmaceuticalsAustin

Pharmaceuticals -

Nanohealth

Pulmonary therapeutics for cancer and other

conditions$1.9

ScanTech Sciences HoustonEnvironmental

HealthFood sterilization technology $2

Seno Medical

InstrumentsSan Antonio Medical Devices Laser optical for cancer scanning $2

SeprOx TheWoodlands

Medical Devices Pure oxygen technology device $.75

Smart Imaging

TechnologiesHouston

Environmental

Health -

Nanohealth

Automated water-borne pathogen detection system $1

Smartfield LubbockAgricultural

TechnologyReal-time irrigation row crop sensor $1

Stellarray Austin

Medical Devices –

Nanohealth – Envi-

ronmental Health

Medical products sterilization & medical imaging $.75


33



Company/ Entity


(in Millions)

Sunrise Ridge Algae Houston Biofuels Algae feedstock for bioenergy $.25

Terapio Austin Biopharmaceuticals Biotherapeutics for radiation countermeasures $1.7

TerrabonBryan,

HoustonBiofuels Conversion of non-food biomass into biofuels $2.75

Texas A&M System /

Texas Agriculture

Experiment Station

Pecos Biofuels Algae Biofuels Consortium $4.025

Texas A&M SystemCollege

Station

Biomedicine –

Pharmaceuticals

National Center for Therapeutics Manufacturing

(NCTM)$50


StationBiofuels Texas BioEnergy Alliance $3.4


Station

Medical Devices -

BiomedicineTexas Institute for Preclinical Studies (TIPS) $6.3


Station

Biodefense –

Pharmaceuticals

TAMU Center for Innovation in Advanced Develop-

ment and Manufacturing (CIADM)$40

Texas A&M Health

Science Center (HSC)Temple

Regenerative Medi-

cine - Biomedicine

Institute of Regenerative Medicine (IRM) – joint ven-

ture with Scott and White and Temple Bioscience

District

$5.25

Texas State University San MarcosHealth Sciences –

Medical DevicesCenter for Multifunctional Materials $4.2

Texas Tech University LubbockAgricultural Bio-

technologyAgricultural genomics R&D (recruited Dr. Wilkins) $2

Thrombovision Houston Medical Devices Platelet measuring device $1.5

University of Houston HoustonBiomedicine -

Pharmaceuticals

Center for Nuclear Receptors and Cell Signaling

(recruited Dr. Jan-Ake Gustafsson) $5.5

University of North

Texas HSCFort Worth

Health Information

Technology -

Biodefense

Center for Commercialization of Fluorescence

Technology$2.38

University of Texas at

AustinAustin

Health Sciences –

Medical Devices

Imaging Research Center (FKA Neuroscience Imaging

Center)$3.67

University of Texas

HSCHouston

Biomedicine -

Nanohealth

Biomedical nanotechnology R&D now DBA Alliance

for NanoHealth (ANH) (recruited Dr. Mauro Ferrari,

now ANH President)

$2.65

University of Texas

HSCHouston Health Sciences Center for Translational Injury Research (CeTIR) $4

University of TexasHSC Houston Health Sciences Children’s Regenerative Medicine $3.15

University of Texas

HSCSan Antonio

Health Sciences –

Medical Devices

Comprehensive Facility for Animal Imaging Research

(CFAIR) – drug and medical device testing$4.1

University of Texas

HSCHouston Pharmaceuticals

Texas Therapeutics Institute – a consortium of

UTHSC Houston, MD Anderson, and UT Austin$6.3

University of Texas at

TylerTyler

Environmental

Health

Texas Allergy, Indoor Environment and Energy

(TxAIRE) Institute

$3.93


34



Company/ Entity


(in Millions)

Vapogenix Houston PharmaceuticalsDevelopment of a novel, non-opioid analgesics for

pain management$2

ViroXis San AntonioBio-

Pharmaceuticals Botanically-based therapies for dermal conditions $2.5

Visualase Houston Medical Devices Image-guided laser technology for cancer therapy $.75

Vital Art and Science

(VAS)Richardson Medical Devices

Home-based device to monitor retinal function

(vision) for patients with macular degeneration and

diabetic retinopathy

$1

VUV Analytics Austin Medical DevicesDevelopment of a molecular spectroscopy product

operating at the nanoscale$1

Xeris Pharmaceuticals Austin PharmaceuticalsDevelopment of patient-friendly injectables for indi-

cations in diabetes, epilepsy, and immunology$1.9

ZS Pharma Fort Worth PharmaceuticalsOral sorbent to remove toxins in the treatment of

kidney and liver disease$2

TOTAL --- --- --- $277.89 M


35



Biodiesel Coalition of Texas (BCOT) at http://biodieselcoalitionoftexas.orgA non-profit association website with statewide biodiesel industry information, links, and more.

BioHouston at www.biohouston.org

A Houston non- profit association’s website with regional biotechnology business resources.

BioMed SA at www.biomedsa.org A San Antonio non- profit association’s website provides information about regional biomedical resources.

Biotechnology Industry Organization (BIO) at www.bio.org A U.S. biotechnology industry association website with statistics, reports, charts, links, and more.

Cancer Prevention and Research Initiative of Texas (CPRIT) at www.cprit.state.tx.us

The CPRIT website contains information about this state agency including grant project details.

The Center for Life Sciences Technology (CLiST) at www.texasbiotech.orgThe website of this Houston-based Center, housed at the University of Houston, provides information on regional resources and news.

International Service for the Acquisition of Agri-Biotech Applications (ISAAA) at www.isaaa.orgA non-profit international association website with global information on genetically modified biotechnology crops.

Medical Devices Manufacturers Assn. (MDMA) at www.medicaldevices.orgA U.S. industry association website with medical devices news, resources, and links.

National Biodiesel Board (NBB) at www.biodiesel.orgA national trade association offering industry news, biodiesel plants data, statistics, papers, links, and much more.

National Institutes of Health (NIH) at www.nih.gov The U.S. government agency website includes many reports and statistics.

National Science Foundation (NSF) at www.nsf.govThis U.S. government agency funds much of the nation’s basic research and publishes many reports and statistics on its website.

The Pharmaceutical Research & Manufacturers of America (PhRMA) at www.phrma.org The major U.S. pharmaceutical industry association’s website with news and industry information.

Renewable Fuels Association (RFA) at www.ethanolrfa.orgA U.S. industry association website with biorefinery locations data, industry production statistics, and much more.

State Energy Conservation Office (SECO) at www.seco.cpa.state.tx.usThe Texas Comptroller of Public Account’s SECO website offers information focused on cost -effective clean energy technologies in Texas,funding and incentives, SECO programs, and much more.

Texas Bio Corridor Alliance at www.texasbiocorridor.org A non-profit organization formed to support and promote the life sciences along I-35 in Texas, from San Antonio to Dallas/Fort Worth.

Texas Department of Agriculture — Bioenergy www.texasagriculture.gov/Home/ProductionAgriculture/Bioenergy.aspx A Texas state agency website with information and data resources on Texas bioenergy.

Texas Emerging Technology Fund (TETF) at www.emergingtechfund.com

The Texas Office of the Governor’s TETF program website area providing TETF awards information, program contacts, news, and more.

Texas Healthcare & Bioscience Institute (THBI) at www.thbi.com

THBI serves as an advocate and resource for the Texas biotechnology industry and legislators.

Texas Medical Device Alliance at http://www.texmda.org/

A non-profit organization established to assist medical device entrepreneurs and companies statewide.

USDA’s Economic Research Service (ERS) website at www.ers.usda.gov The ERS is the primary source of U.S. Department of Agriculture (USDA) economic information and research. Its website provides a wealthof data, including some international statistics.

Appendix 2: Selected Industry ResourcesAppendix 2: Selected Industry ResourcesAppendix 2: Selected Industry Resources

36

http://biodieselcoalitionoftexas.org/index.php

http://www.biohouston.org/

http://www.biomedsa.org/


http://www.bio.org/

http://www.bio.org/

http://www.cprit.state.tx.us/

http://www.texasbiotech.org/

http://www.isaaa.org/

http://www.medicaldevices.org/

http://www.biodiesel.org/

http://www.nih.gov/

http://www.nih.gov/

http://www.nsf.gov/

http://www.phrma.org/


http://www.ethanolrfa.org/

http://www.seco.cpa.state.tx.us/

http://www.texasbiocorridor.org/


http://www.texasagriculture.gov/Home/ProductionAgriculture/Bioenergy.aspx


http://www.emergingtechfund.com/

http://www.thbi.com/

http://www.ers.usda.gov/



http://www.thbi.com/

http://www.emergingtechfund.com/



http://www.seco.cpa.state.tx.us/

http://www.ethanolrfa.org/


http://www.nsf.gov/

http://www.nih.gov/

http://www.biodiesel.org/

http://www.medicaldevices.org/

http://www.isaaa.org/

http://www.texasbiotech.org/

http://www.cprit.state.tx.us/

http://www.bio.org/


http://www.biohouston.org/

http://biodieselcoalitionoftexas.org/index.php



Office of the Governor

Economic Development and Tourism

PO Box 12428, Austin, TX 78711

512-936-0101

www.TexasWideOpenForBusiness.com

Documents

Texas Biotech Report 2012