Teaching Herpes Zoster

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    TEACHING BANGSAL 1Herpes Zooster

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    GROUP MEMBERS

    Dian Utami C 111 09 134Arsyi Adliah Anwar C 111 09 266

    Andi Utari Dwi Rahayu C 111 09 280

    Eka Utami Makmur C 111 09 291

    M. Awwalul Akram C 111 09 262

    Ahmad Zaki C 111 09 320

    Arie Rhoedyat Swardhani C 111 08 167

    Ryan Kanzul Arasy C 111 08 128 Muh. Luqmanul Hakim C 111 08 765

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    PATIENT IDENTITY

    Name : Mrs. Bayang Dg Nganga

    Gender : Female

    Age : 82 years old

    Marital status : Marriage

    Religion : Moeslim

    Address : Salaka, Takalar

    Job : Housewife

    Addmission date : 29 / 01 / 2013

    Medical record no : 591482

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    HISTORY TAKING

    Main Complaint: wound on the left side of uppernose.

    Brief Anamnesis : Occur since 5 day ago. Itchy

    (+), swelling (+), red rash (+), nausea (+), vomit(+), epigastric pain (+), cough (-), dyspneu (-),

    chest pain (-), fever (-), fever history (-),

    defecation and micturition are normal.

    Hypertension history (+). No family members

    with the same disease.

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    CURRENT STATUS

    Consciousness : Compos Mentis

    General Condition : Moderate

    Hygiene : Moderate

    Nutrition : Normal

    Vital sign :

    BP : 120/80 mmHg

    Pulse : 80 minutes

    RR : 24x/minutes

    Temperature : 36,5 0C

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    PHYSICAL EXAMINATION

    Anemic (-), icterus (-), cyanoses (-)

    Cor/ Pulmonal : Normal

    Abdomen : Normal,peristaltic (+)

    Extremities : Edema (-)

    Lymph nodes : Enlargement (-)

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    Regio facialis

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    DERMATO-VENEROLOGY STATUS

    Region : superior nasalis sinistra

    Efflorescency : granulated tissue and

    crusta

    Region : anterior nasalis sinistra

    Efflorescency : crusta and skuama

    Region : Orbitalis (palpebra

    superior) sinistraEfflorescency : oedem and erithema

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    RESUME

    An 82-years-old woman with main complaint

    is wound on the left side of upper nose.

    Occur since 5 day ago. Patient feels Itchy

    (+), swelling (+), red rash (+), nausea (+),vomit (+), epigastric pain (+), cough (-),

    dyspneu (-), chest pain (-), fever (-), fever

    history (-), defecation and micturition arenormal. Hypertension history (+).

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    DIAGNOSIS

    Herpes Zoozter Facialis

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    DISCUSSION

    Herpes Zoster is an acute dermatomal infectionassociated with reactivation of VZV

    Characterized by :

    Unilateral pain

    A vesicular or bullous eruption limited to a

    dermatome(s) innervated by a corresponding

    sensory ganglion.

    Age of Onset : More than 66% are >50 years ofage; 5% of cases in children

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    CLINICAL MANIFESTATIONS

    Duration of Symptoms

    Prodromal stage: Neuritic pain or

    paresthesia precedes for 23 weeks(84% of cases).

    Acute vesiculation: 35 days.

    Crust formation: days to 23 weeks.

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    PHN: months to years.

    Chronic pain or PHN (post herpetic

    neuralgia) is that persisting after the

    lesions have healed or persisting 4

    weeks after the onset of lesions,

    regardless of degree of healing.

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    SKIN SYMPTOMS

    Prodromal Stage

    Pain (stabbing, pricking, sharp, boring,

    penetrating, lancinating, shooting),

    tenderness, paresthesia (itching, tingling,burning, freezeburning) in the involved

    dermatome precedes the eruption.

    Allodynia: heightened sensitivity to mild

    stimuli.

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    CONSTITUTIONAL SYMPTOMS

    Prodromal stage and active vesiculation:

    flulike symptoms such as headache,

    malaise, fever.

    Chronic stages: depression is very commonin individuals with PHN.

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    MUCOCUTANEOUS LESIONS

    Papules (24 h) vesicles-bullae ( (48h)

    pustules (96 h) crusts (710 days).

    New lesions continue to appear for up to 1

    week. Erythematous, edematous base with

    superimposed clear vesicles, sometimes

    hemorrhagic.

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    The vesicle-bulla is oval or round, may be

    umbilicated.

    Vesicles erode forming crusted erosions

    Necrotic and gangrenous lesions sometimes

    occur.

    Scarring is common after healing of HZ

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    DISTRIBUTION

    Unilateral, dermatomal .

    Two or more contiguous dermatomes may

    be involved .

    Noncontiguous dermatomal zoster is rare.

    Hematogenous dissemination to other skin

    sites in 10% of healthy individuals.

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    DIFFERENTIAL DIAGNOSIS

    Prodromal Stage/Localized Pain Can

    mimic

    migraine, cardiac or pleural disease, an

    acute abdomen, or vertebral disease.Dermatomal Eruption Zosteriform HSV

    infection

    phytoallergic (poison ivy, poison oak)contactdermatitis, erysipelas, bullous impetigo,

    necrotizing fasciitis.

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    TREATMENT

    Antiviral therapy:

    o Systemic Antiviral (Acyclovir,

    Famcyclovir, Valacyclovir)

    o Urgent indications

    o Herpes zoster at any site of the body

    in patients beyond the age of 50

    o Herpes zoster in the head/neck area of

    patient at any age

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    o Severe herpes zoster on the trunk and on the

    limbo Herpes zoster in immunodeficient patients

    o Herpes Zoster in patient severe atopic

    dermatitis and severe eczema

    Relative indications:

    o Herpes Zoster on the trunk or on the extremities

    in patients younger than 50 years

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    DOSAGE

    Acyclovir : 800 mg PO four times daily

    for 710 days

    Valacyclovir : 1000 mg PO three times

    daily for 7 days

    Famcyclovir : 500 mg PO three times

    daily for 7 days

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    SYMPTOMATIC THERAPY

    Analgesic :

    1) Ibuprofen

    2) Mefenamic acid

    Anti Pruritus :

    3) Antihistamine

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    RECOMMENDED EXAMINATION

    Tzank examination polynuclear of datia cell

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    THANK YOU