Tatt2Away

Trans Epidermal Pigment Release

A Non Laser Technique forTattoo Removal

by

Rejuvatek Medical Inc.

Company Profile

• Formed in 2008, Incorporated 2009 (LLC), Incorporated 2011 (INC)

• Formed to bring new technologies to cosmetic surgery and aesthetics segments

• Researched existing methods for tattoo removal, deemed inadequate, high-cost technology with low patient satisfaction

• Goal – reduce cost of equipment while increasing the satisfaction level of patients

• Bring a new Standard of Care to the tattoo removal

Management Team

• Jack Savage, President/CEO– Over 30 years in the Medical Market space creating revenue, profits, and

market-share growth with extensive background in medical lasers.– Demonstrated leader providing vision in start ups, early-stage, and

pioneering technology such as American Lasers, HGM Lasers, and Orbtek.

• Wheat Bailey, VP Sales– Nearly 40 years of extensive management, business consulting, sales

management, and sales experience in the Medical Aesthetic Center / Medical Spa sector.

• Shilo Case, Director Marketing– Nearly 18 years of comprehensive experience in developing, managing, and

implementing marketing and branding strategies in a variety of industries including medical devices, architectural-engineering, and The Olympics

Brief History of Tattoo Pigments

• 1980’s saw development of synthetic tattoo pigments with brighter and more varied colors.

• All pigments - mostly derived from consumer product pigments and dyes, which may include a blend of chemicals used for making paint and ink.

• What’s in the ink:– Additives to increase ‘wettability’

– Bonding agents to help the pigment stick to the needles

– Ethanol and isopropanol for sterility– Pigment color– Whatever the artist decides to add based on tradition – Listerine, Vodka

What is in the Pigment?

• Significantly 39% of the 28 most commonly used pigments in tattoo ink are NOT allowed in cosmetics

• 17% of 52 pigments used in tattooing contain a carcinogenic amine, which may include– Mercury Salts – Cinnabar (Red)

– Cadmium Sulphide (Yellow)

– Manganese (Purple)

– Trivalent Chromic Oxide (Green)– Cobalt (Blue)

• The distribution chain for raw pigments is complex and difficult to regulate

Tattoo Pigment in the Skin

Why is this important?

Because the person removing pigment with a laser has no idea what is in the pigment being removed (absorbed)!!!

Approximately 2mm depth

Tattoo Removal MethodsThe Problem!

Currently, there is no guaranteed method of removing all tattoo pigment without leaving some sort of mark or evidence that something has been there before.

Skin Mark / Scar vs. Pigment Remaining

• Excision

• Resurfacing

• Laser

• Escharotics

Removal by Excision

Direct Closure Skin graft

Removal by Resurfacing

Derm-abrasion

Removal by Laser

Pros• Perceived as state of the art• Can eliminate some pure

tattoo colors without much mark. Typically, only darker colors– Dark Blue– Black– Some Reds

Cons• Slow & painful• Risk of breakdown of

pigment products• Variable elimination• Expensive • Scar potential• Allergic reaction• Darkening of pigment• Skin pigment changes

Most Common Options:CO2, Pulsed Nd:YAG, Q-Switched Ruby, and IPL

Laser Removal Results

Escharotic Technique

Options:

Nitric Acid, Phenol, Tannic acid paste – tattooed in + AgNO3, Potassium permanganate, and

Trans-Epidermal Pigment Release (TEPR)

®

• Novel method eliminating pigment decomposition and transmission to vital organs

• Requires qualified technician

Tatt2Away

Mechanisms of Action:– Like reverse tattooing– Removes epithelium– Natural product (TEPRSOL) introduced into dermis– Eschar formation and variable thickness skin injury created

Discussion:– Small area treatments– Effectively removes ALL pigment colors– Potentially quicker than laser due to reduced number of visits

needed– Can be used as adjunct to laser

• Tatt2Away Driver Module• Metered Pump System• Escharotic Hand Piece

Tatt2Away System

*Cart not included

Tatt2Away Pre-treatment

Skin Preparation:

•Wash, shave, and sterilize the area

•Local anesthetic injected or topical

Needle Preparation According to Location:

•Deep enough to reach tattoo pigment

•Selectable Needle Depth to minimize risk of scarring

•Adjustable calibration feature on delivery hand piece is set to optimum depth depending on tattoo location

Tatt2Away TreatmentTemplate - Intellectual Property

5mm circle

Skin Bridge

First Treatment Pattern

Second Treatment Pattern

Third Treatment Pattern

• 5mm recommended• Dot Template - useful for consistency• 3mm skin bridge• Scratch technique

The Tatt2Away Wound

Immediate post treatment

Immediate post treatment

Tatt2Away Post-treatment

Dressings:

•Dry dressing

•Tape dressing

•Silicone dressing

•Biafine

Can we reduce the series?• Improve patient selection• Full understanding of risk factors• Allow adequate time between treatments

Tatt2Away Results

Immediate post Treatment

Intermediate – 4 Weeks

First Results at 8 Weeks

Tatt2Away Results

After 3 treatments

Note: complete pigment removal and return to normal skin color. Original moles on the skin have lost tattoo pigment and returned to normal light brown color.

Single treatment to remove green/black tattoo

Tatt2Away Results

Before

At 24 Weeks

During Post Treatment

Tatt2Away Results

At 12 Months

Before Second Treatment

Before Fourth Treatment

Tatt2Away Market Opportunity

Statistics:

•US Population – 314,201,000 (wikipedia.org)

•21% Americans have a tattoo (65.9M Americans) (wikipedia.org)

•17% of Americans regret their tattoo (The Journal of the American Academy of Dermatology, March 2005)

•11% of Americans are getting tattoo removal (The Journal of the American Academy of Dermatology, March 2005)

Marketing Potential:

•65.9M x 17% = 11.2M Potential Removals* $19.6B

•65.9M x 11% = 7.3M Planned Removals* $12.8B*5 Treatments per Tatt2Away Removal at $350 each = $1,750/removal

Americans spend $1.65 Billion annually on tattoos and access to over 21,000 tattoo parlors in the US. (Pew Research Center, July 2012)

What does this mean? The Market is continually growing.

Tatt2Away Financial Model

Assumptions:

•Four treatments per patient

•$350 per treatment

•Estimates presented low, medium, high

•Expenses not included pending further discussions

•See separately attached spreadsheet

Summary

Pros:

•Enormous underserved market

•Viable low-cost solution

•Solves major objections to existing technology– Expels pigment rather than absorbs– Color-blind technology– Less treatments– Lower costs

Cons:

•Patient fall out

•Might be seasonal

•Qualified technician

•Patient compliance

•Significant marketing budget