29
Table Of Contents Table Of Contents Table Of Contents February 6, 2012 / Analyst’s Handbook: Health Care www.yardeni.com Yardeni Research, Inc. S&P 500 Health Care 1 S&P 500 Health Care (cont) 2 S&P 400: Health Care 3 S&P 400 Health Care (cont) 4 Health Care: S&P Sector and Cap, Year-to-Date 5 Health Care Sector 6-7 Biotechnology 8-9 Health Care Distributors 10-11 Health Care Equipment 12-13 Health Care Facilities 14-15 Health Care Services 16-17 Managed Health Care 18-19 Pharmaceuticals 20-21 Relative Earnings & P/E: Health Care 22-23 Profit Margin 24 Earnings Growth 25 Earnings Growth Spreads 26 Pricing 27

Table Of Contents Table Of Contents Table Of …Figure 4. 98 99 00 01 02 03 04 05 06 07 08 09 10 11 12 13 14 100 200 300 400 500 600 700 800 S&P 400 PHARMACEUTICALS_____ 2/3 …

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Page 1: Table Of Contents Table Of Contents Table Of …Figure 4. 98 99 00 01 02 03 04 05 06 07 08 09 10 11 12 13 14 100 200 300 400 500 600 700 800 S&P 400 PHARMACEUTICALS_____ 2/3 …

Table Of Contents Table Of ContentsTable Of Contents

February 6, 2012 / Analyst’s Handbook: Health Care www.yardeni.com

Yardeni Research, Inc.

S&P 500 Health Care 1S&P 500 Health Care (cont) 2S&P 400: Health Care 3S&P 400 Health Care (cont) 4Health Care: S&P Sector and Cap, Year-to-Date 5Health Care Sector 6-7Biotechnology 8-9Health Care Distributors 10-11Health Care Equipment 12-13Health Care Facilities 14-15Health Care Services 16-17Managed Health Care 18-19Pharmaceuticals 20-21Relative Earnings & P/E: Health Care 22-23Profit Margin 24Earnings Growth 25Earnings Growth Spreads 26Pricing 27

Page 2: Table Of Contents Table Of Contents Table Of …Figure 4. 98 99 00 01 02 03 04 05 06 07 08 09 10 11 12 13 14 100 200 300 400 500 600 700 800 S&P 400 PHARMACEUTICALS_____ 2/3 …

Figure 1.

98 99 00 01 02 03 04 05 06 07 08 09 10 11 12 13 14200

300

400

500

2/3

S&P 500 HEALTH CARE

98 99 00 01 02 03 04 05 06 07 08 09 10 11 12 13 14200

250

300

350

400

450

500

550

600

650

700

2/3

S&P 500 HEALTH CARE EQUIPMENT(BAX BCR BDX BSX CFNwi HSP ISRGMDT STJ SYK VAR ZMH)

98 99 00 01 02 03 04 05 06 07 08 09 10 11 12 13 140

200

400

600

800

1000

1200

14002/3S&P 500 BIOTECHNOLOGY

(AMGN BIIB CELG GENZ GILD)

98 99 00 01 02 03 04 05 06 07 08 09 10 11 12 13 140

50

100

150

200

250

2/3

S&P 500 HEALTH CARE FACILITIES(THC)

98 99 00 01 02 03 04 05 06 07 08 09 10 11 12 13 14100

150

200

250

300

350

400

2/3

S&P 500 HEALTH CARE DISTRIBUTORS(ABC CAH MCK PDCO)

200-day moving average

Source: Standard and Poor’s Corporation.

98 99 00 01 02 03 04 05 06 07 08 09 10 11 12 13 1480

120

160

200

240

280

320

360

400

440

480

520

560

2/3

yardeni.com

S&P 500 HEALTH CARE SERVICES(DGX DVA ESRX LH MHS)

- S&P 500 Health Care -

Page 1 / February 6, 2012 / Analyst’s Handbook: Health Care www.yardeni.com

Yardeni Research, Inc.

Page 3: Table Of Contents Table Of Contents Table Of …Figure 4. 98 99 00 01 02 03 04 05 06 07 08 09 10 11 12 13 14 100 200 300 400 500 600 700 800 S&P 400 PHARMACEUTICALS_____ 2/3 …

Figure 2.

98 99 00 01 02 03 04 05 06 07 08 09 10 11 12 13 1450

100

150

200

250

300

350

400

450

500

550

600

650

2/3

S&P 500 MANAGED HEALTH CARE(AET CI CVH HUM UNH WLP)

1998 2000 2002 2004 2006 2008 2010 2012 2014200

250

300

350

400

450

500

550

600

2/3

S&P 500 PHARMACEUTICALS_________________________ABT AGN BMY BRL FRX JNJ LLYMRK MYL PFE SGP WPI WYE

yardeni.com

- S&P 500 Health Care (cont) -

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Yardeni Research, Inc.

Page 4: Table Of Contents Table Of Contents Table Of …Figure 4. 98 99 00 01 02 03 04 05 06 07 08 09 10 11 12 13 14 100 200 300 400 500 600 700 800 S&P 400 PHARMACEUTICALS_____ 2/3 …

Figure 3.

98 99 00 01 02 03 04 05 06 07 08 09 10 11 12 13 14200

250

300

350

400

450

500

550

600

2/3

S&P 400 HEALTH CARE

98 99 00 01 02 03 04 05 06 07 08 09 10 11 12 13 14225

275

325

375

425

475

525

575

625

675

725

2/3

S&P 400 HEALTH CARE EQUIPMENT_______________________________BEC CYTC EW EYE HB IMDC ISRG STEVAR VARI

98 99 00 01 02 03 04 05 06 07 08 09 10 11 12 13 14300

400

500

600

700

800

900

1000

1100

2/3

S&P 400 BIOTECHNOLOGY_______________________AFFX CEPH CRL IVGN MATK MLNM PDLITECH VRTX

98 99 00 01 02 03 04 05 06 07 08 09 10 11 12 13 1450

100

150

200

250

2/3

S&P 400 HEALTH CARE FACILITIES______________________________CYH LPNT TRI UHS WOOF

98 99 00 01 02 03 04 05 06 07 08 09 10 11 12 13 14200

250

300

350

400

450

500

550

2/3

S&P 400 HEALTH CARE DISTRIBUTORS___________________________________HSIC

98 99 00 01 02 03 04 05 06 07 08 09 10 11 12 13 1480

100

120

140

160

180

200

220

240

260

280

2/3

yardeni.com

S&P 400 HEALTH CARE SERVICES______________________________AHG CVD LNCR OCR PPDI

- S&P 400: Health Care -

Page 3 / February 6, 2012 / Analyst’s Handbook: Health Care www.yardeni.com

Yardeni Research, Inc.

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Figure 4.

98 99 00 01 02 03 04 05 06 07 08 09 10 11 12 13 14100

200

300

400

500

600

700

8002/3S&P 400 PHARMACEUTICALS_________________________

MRX PRGO PRX SEPR VRX

200-day moving average.Source: Standard & Poor’s Corporation.

98 99 00 01 02 03 04 05 06 07 08 09 10 11 12 13 140

100

200

300

400

2/3

S&P 400 MANAGED HEALTH CARE______________________________HNT

- S&P 400 Health Care (cont) -

Page 4 / February 6, 2012 / Analyst’s Handbook: Health Care www.yardeni.com

Yardeni Research, Inc.

Page 6: Table Of Contents Table Of Contents Table Of …Figure 4. 98 99 00 01 02 03 04 05 06 07 08 09 10 11 12 13 14 100 200 300 400 500 600 700 800 S&P 400 PHARMACEUTICALS_____ 2/3 …

-10

0

10

20

Figure 5.S&P 500 Large Cap

All Sectors

-20

-10

0

10

20

10.5

S&P 400 MidCap

-20

-10

0

10

20

11.7

S&P 600 SmallCap

-10-505

10152025

4.1

Health CareSector

-10-505

10152025

12.0

-10

0

10

20

30

40

50

-30

-10

10

30

50

70

14.2Biotechnology

-30

-10

10

30

50

70

29.8

-30

-10

10

30

50

70

9.5

-10

0

10

20

30

4.4

Health CareDistributors

-10

0

10

20

30

13.2

-10

0

10

20

30

10.0

-25

-15

-5

5

15

25

10.3Health CareEquipment

-25

-15

-5

5

15

25

11.0

-25

-15

-5

5

15

25

10.0

-50

-30

-10

10

30

16.4

Health CareFacilities

-50

-30

-10

10

30

8.5

-50

-30

-10

10

30

11.0

-30

-20

-10

0

10

20

30

11.9Health CareServices

HC Supplies

Health CareTechnology

-30

-20

-10

0

10

20

30

2.4

-30

-20

-10

0

10

20

30

8.6

-15

-5

5

15

25

8.2

-20

0

20

40

60

80

1.5

Figure 11.S&P 500 LargeCap

ManagedHealth Care

-20

0

20

40

60

80

16.1

S&P 400 MidCap

-20

0

20

40

60

80

8.8

S&P 600 SmallCap

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec2012

-30

-10

10

30

50

-1.4Pharmaceuticals

Source: Standard & Poor’s Corporation.

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec2012

-30

-10

10

30

50

5.2

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec2012

-30

-10

10

30

50

3.8

yardeni.com

- Health Care: S&P Sector and Cap, Year-to-Date -

Page 5 / February 6, 2012 / Analyst’s Handbook: Health Care www.yardeni.com

Yardeni Research, Inc.

Page 7: Table Of Contents Table Of Contents Table Of …Figure 4. 98 99 00 01 02 03 04 05 06 07 08 09 10 11 12 13 14 100 200 300 400 500 600 700 800 S&P 400 PHARMACEUTICALS_____ 2/3 …

1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 201280

130

180

230

280

330

380430480530

80

130

180

230

280

330

380430480530

2/3

yardeni.com

S&P 500 HEALTH CARE INDEX*

* Ratio scale.

200-day moving average

Figure 6.

1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 20125

10

15

20

25

30

3540

5

10

15

20

25

30

3540

Jan

yarden

i.com

S&P 500 HEALTH CARE OPERATING EARNINGS PER SHARE(analysts’ average forecasts, ratio scale)

Consensus Forecasts__________________

Annual estimates

12-month forward*

0809

10 1112

9.7 15.4 8.9 14.4 13.5 9.9 9.3 7.8 9.6 11.1 8.2 7.3 14.0 8.1 0.9 10.3 7.9 4.6

* Time-weighted average of current and next year’s consensus earnings estimates. Numbers above time line are annual growth rates.

Figure 7.

1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 20126

10

14

18

22

26

30

34

6

10

14

18

22

26

30

34

Jan

yardeni.com

S&P 500 HEALTH CARE VALUATION

P/E*

S&P 500 P/E*

* Price divided by 12-month forward consensus expected operating earnings per share using mid-month data. Sources for all charts: Standard & Poor’s Corporation, Thomson Financial, and Haver Analytics.

Figure 8.

- Health Care Sector -

Page 6 / February 6, 2012 / Analyst’s Handbook: Health Care www.yardeni.com

Yardeni Research, Inc.

Page 8: Table Of Contents Table Of Contents Table Of …Figure 4. 98 99 00 01 02 03 04 05 06 07 08 09 10 11 12 13 14 100 200 300 400 500 600 700 800 S&P 400 PHARMACEUTICALS_____ 2/3 …

1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012.7

.8

.9

1.0

1.1

1.2

1.3

1.4

1.5

.7

.8

.9

1.0

1.1

1.2

1.3

1.4

1.5

Jan

yardeni.com

S&P 500 HEALTH CARE SECTOR RELATIVE VALUATION

P/E Relative to S&P 500*

* Price divided by 12-month forward consensus expected operating earnings per share using mid-month data. Sources for all charts: Standard & Poor’s Corporation, Thomson Financial, and Haver Analytics.

Figure 9.

1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012-25

-20

-15

-10

-5

0

5

10

15

20

-25

-20

-15

-10

-5

0

5

10

15

20

Jan

yardeni.com

S&P 500 HEALTH CARE NET REVISIONS*(% estimates up less down)

* Three-month moving average of 12-month forward consensus expected operating earnings per share using mid-month consensus forecast.

Figure 10.

1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 20124

6

8

10

12

14

16

4

6

8

10

12

14

16

Q3

yardeni.com

S&P 500 HEALTH CARE PROFIT MARGIN(trailing 4-quarter EPS, percent) Operating Profit Margin___________________

S&P 500 Composite

Sector

Sources for all charts: Standard & Poor’s Corporation, Thomson Financial, and Haver Analytics.

Figure 11.

- Health Care Sector -

Page 7 / February 6, 2012 / Analyst’s Handbook: Health Care www.yardeni.com

Yardeni Research, Inc.

Page 9: Table Of Contents Table Of Contents Table Of …Figure 4. 98 99 00 01 02 03 04 05 06 07 08 09 10 11 12 13 14 100 200 300 400 500 600 700 800 S&P 400 PHARMACEUTICALS_____ 2/3 …

1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 201475

225

375

525

675

825975112512751425

75

225

375

525

675

825975

112512751425 2/3

yardeni.com

S&P 500 BIOTECHNOLOGY INDEX*(AMGN BIIB CELG GILD)

* Ratio scale.

200-day moving average

Figure 12.

1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 20125

25

45

65

85

105

5

25

45

65

85

105 Jan

yarden

i.com

S&P 500 BIOTECHNOLOGY OPERATING EPS(analysts’ average forecasts, ratio scale)

Consensus Forecasts__________________

Annual estimates

12-month forward*

0809

1011 12

24.7 25.0 14.8 20.1 24.3 0.3 4.7 17.0 34.4 12.8 31.2 29.5 18.0 15.0 10.4 12.5 9.0 10.9

* Time-weighted average of current and next year’s consensus earnings estimates. Numbers above time line are annual growth rates.

Figure 13.

1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 20125

10

15

20

25

30

35

40

45

50

55

60

65

70

5

10

15

20

25

30

35

40

45

50

55

60

65

70

Jan

yardeni.com

S&P 500 BIOTECHNOLOGY VALUATION

P/E*

S&P 500 P/E*

* Price divided by 12-month forward consensus expected operating earnings per share using mid-month data. Sources for all charts: Standard & Poor’s Corporation, Thomson Financial, and Haver Analytics.

Figure 14.

- Biotechnology -

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Yardeni Research, Inc.

Page 10: Table Of Contents Table Of Contents Table Of …Figure 4. 98 99 00 01 02 03 04 05 06 07 08 09 10 11 12 13 14 100 200 300 400 500 600 700 800 S&P 400 PHARMACEUTICALS_____ 2/3 …

1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012.50

.75

1.00

1.25

1.50

1.75

2.00

2.25

2.50

2.75

.50

.75

1.00

1.25

1.50

1.75

2.00

2.25

2.50

2.75

Jan

yardeni.com

S&P 500 BIOTECHNOLOGY RELATIVE VALUATION

P/E Relative to S&P 500*

* Price divided by 12-month forward consensus expected operating earnings per share using mid-month data. Sources for all charts: Standard & Poor’s Corporation, Thomson Financial, and Haver Analytics.

Figure 15.

1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012-40

-30

-20

-10

0

10

20

30

40

50

60

70

-40

-30

-20

-10

0

10

20

30

40

50

60

70

Jan

yardeni.com

S&P 500 BIOTECHNOLOGY NET REVISIONS*(% estimates up less down)

* Three-month moving average of 12-month forward consensus expected operating earnings per share using mid-month consensus forecast.

Figure 16.

1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 20120

5

10

15

20

25

30

35

40

0

5

10

15

20

25

30

35

40

Q3

yardeni.com

S&P 500 BIOTECHNOLOGY PROFIT MARGIN(trailing 4-quarter EPS, percent)

Operating Profit Margin____________________

S&P 500 Composite

Industry

Sources for all charts: Standard & Poor’s Corporation, Thomson Financial, and Haver Analytics.

Figure 17.

- Biotechnology -

Page 9 / February 6, 2012 / Analyst’s Handbook: Health Care www.yardeni.com

Yardeni Research, Inc.

Page 11: Table Of Contents Table Of Contents Table Of …Figure 4. 98 99 00 01 02 03 04 05 06 07 08 09 10 11 12 13 14 100 200 300 400 500 600 700 800 S&P 400 PHARMACEUTICALS_____ 2/3 …

1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 201295

145

195

245

295

345

395

95

145

195

245

295

345

395

2/3

yardeni.com

S&P 500 HEALTH CARE DISTRIBUTORS INDEX*(ABC CAH MCKPDCO)

* Ratio scale.

200-day moving average

Figure 18.

1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 20124

8

12

16

20

24

2832

4

8

12

16

20

24

2832

Jan

yarden

i.com

S&P 500 HEALTH CARE DISTRIBUTORS OPERATING EARNINGS PER SHARE(analysts’ average forecasts, ratio scale)

Consensus Forecasts__________________

Annual estimates

12-month forward* 08

0910 11

12

18.4 17.3 3.7 11.5 -11.7 2.7 29.0 34.7 18.8 3.9 -8.6 11.4 12.4 13.2 1.0 -7.7 23.7 11.6

* Time-weighted average of current and next year’s consensus earnings estimates. Numbers above time line are annual growth rates.

Figure 19.

1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 20125

10

15

20

25

30

35

5

10

15

20

25

30

35

Jan

yardeni.com

S&P 500 HEALTH CARE DISTRIBUTORS VALUATION

P/E*

S&P 500 P/E*

* Price divided by 12-month forward consensus expected operating earnings per share using mid-month data. Sources for all charts: Standard & Poor’s Corporation, Thomson Financial, and Haver Analytics.

Figure 20.

- Health Care Distributors -

Page 10 / February 6, 2012 / Analyst’s Handbook: Health Care www.yardeni.com

Yardeni Research, Inc.

Page 12: Table Of Contents Table Of Contents Table Of …Figure 4. 98 99 00 01 02 03 04 05 06 07 08 09 10 11 12 13 14 100 200 300 400 500 600 700 800 S&P 400 PHARMACEUTICALS_____ 2/3 …

1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012.50

.75

1.00

1.25

1.50

1.75

2.00

2.25

.50

.75

1.00

1.25

1.50

1.75

2.00

2.25

Jan

yardeni.com

S&P 500 HEALTH CARE DISTRIBUTORS RELATIVE VALUATION

P/E Relative to S&P 500*

* Price divided by 12-month forward consensus expected operating earnings per share using mid-month data. Sources for all charts: Standard & Poor’s Corporation, Thomson Financial, and Haver Analytics.

Figure 21.

1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012-50

-40

-30

-20

-10

0

10

20

30

40

-50

-40

-30

-20

-10

0

10

20

30

40

Jan

yardeni.com

S&P 500 HEALTH CARE DISTRIBUTORS NET REVISIONS*(% estimates up less down)

* Three-month moving average of 12-month forward consensus expected operating earnings per share using mid-month consensus forecast.

Figure 22.

1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 20120

2

4

6

8

10

0

2

4

6

8

10

Q3

yardeni.com

S&P 500 HEALTH CARE DISTRIBUTORS PROFIT MARGIN(trailing 4-quarter EPS, percent)

Operating Profit Margin____________________

S&P 500 Composite

Industry

Sources for all charts: Standard & Poor’s Corporation, Thomson Financial, and Haver Analytics.

Figure 23.

- Health Care Distributors -

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Yardeni Research, Inc.

Page 13: Table Of Contents Table Of Contents Table Of …Figure 4. 98 99 00 01 02 03 04 05 06 07 08 09 10 11 12 13 14 100 200 300 400 500 600 700 800 S&P 400 PHARMACEUTICALS_____ 2/3 …

1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 201280

180

280

380

480

580

680

80

180

280

380

480

580

680

2/3

yardeni.com

S&P 500 HEALTH CARE EQUIPMENT INDEX*(BAX BCR BDX BSX CFN COV EW HSPISRG MDT STJ SYK VAR ZMH)

* Ratio scale.

200-day moving average

Figure 24.

1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 20125

15

25

35

45

55

5

15

25

35

45

55

Jan

yarden

i.com

S&P 500 HEALTH CARE EQUIPMENT OPERATING EARNINGS PER SHARE(analysts’ average forecasts, ratio scale)

Consensus Forecasts__________________

Annual estimates

12-month forward*

08 0910 11

12

20.9 10.4 7.0 9.5 16.1 3.5 8.1 18.3 12.1 27.3 13.9 -6.4 4.3 13.8 8.1 6.2 9.6 9.7

* Time-weighted average of current and next year’s consensus earnings estimates. Numbers above time line are annual growth rates.

Figure 25.

1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 20125

10

15

20

25

30

35

5

10

15

20

25

30

35

Jan

yardeni.com

S&P 500 HEALTH CARE EQUIPMENT VALUATION

P/E*

S&P 500 P/E*

* Price divided by 12-month forward consensus expected operating earnings per share using mid-month data. Sources for all charts: Standard & Poor’s Corporation, Thomson Financial, and Haver Analytics.

Figure 26.

- Health Care Equipment -

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Yardeni Research, Inc.

Page 14: Table Of Contents Table Of Contents Table Of …Figure 4. 98 99 00 01 02 03 04 05 06 07 08 09 10 11 12 13 14 100 200 300 400 500 600 700 800 S&P 400 PHARMACEUTICALS_____ 2/3 …

1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012.8

1.0

1.2

1.4

1.6

1.8

.8

1.0

1.2

1.4

1.6

1.8

Jan

yardeni.com

S&P 500 HEALTH CARE EQUIPMENT RELATIVE VALUATION

P/E Relative to S&P 500*

* Price divided by 12-month forward consensus expected operating earnings per share using mid-month data. Sources for all charts: Standard & Poor’s Corporation, Thomson Financial, and Haver Analytics.

Figure 27.

1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012-40

-30

-20

-10

0

10

20

30

-40

-30

-20

-10

0

10

20

30

Jan

yardeni.com

S&P 500 HEALTH CARE EQUIPMENT NET REVISIONS*(% estimates up less down)

* Three-month moving average of 12-month forward consensus expected operating earnings per share using mid-month consensus forecast.

Figure 28.

1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 20125

10

15

20

5

10

15

20

Q3

yardeni.com

S&P 500 HEALTH CARE EQUIPMENT PROFIT MARGIN(trailing 4-quarter EPS, percent)

Operating Profit Margin____________________

S&P 500 Composite

Industry

Sources for all charts: Standard & Poor’s Corporation, Thomson Financial, and Haver Analytics.

Figure 29.

- Health Care Equipment -

Page 13 / February 6, 2012 / Analyst’s Handbook: Health Care www.yardeni.com

Yardeni Research, Inc.

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1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 201220

70

120

170

220

270

20

70

120

170

220

270

2/3

yardeni.com

S&P 500 HEALTH CARE FACILITIES INDEX*(THC)

* Ratio scale.

200-day moving average

Figure 30.

1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012-8

-6

-4

-2

0

2

4

6

8

10

12

14

16

-8

-6

-4

-2

0

2

4

6

8

10

12

14

16Jan

yarden

i.com

S&P 500 HEALTH CARE FACILITIES OPERATING EARNINGS PER SHARE(analysts’ average forecasts, ratio scale)

Consensus Forecasts__________________

Annual estimates

12-month forward*

08

09

10

11

12

18.3 13.0 -25.4 9.4 -4.5 1.8 26.6 22.6 -33.2 -23.2 15.6 -22.2 +/- neg -/+ 109.5 32.2 13.9

* Time-weighted average of current and next year’s consensus earnings estimates. Numbers above time line are annual growth rates.

Figure 31.

1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 20125

10

15

20

25

30

5

10

15

20

25

30

Jan

yardeni.com

S&P 500 HEALTH CARE FACILITIES VALUATION

P/E*

S&P 500 P/E*

P/E not available from November 2007 to March 2008 and fromDecember 2008 to July 2009 because earnings were negative.

P/E capped at 25.

* Price divided by 12-month forward consensus expected operating earnings per share using mid-month data. Sources for all charts: Standard & Poor’s Corporation, Thomson Financial, and Haver Analytics.

Figure 32.

- Health Care Facilities -

Page 14 / February 6, 2012 / Analyst’s Handbook: Health Care www.yardeni.com

Yardeni Research, Inc.

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1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012.4

.6

.8

1.0

1.2

1.4

1.6

1.8

.4

.6

.8

1.0

1.2

1.4

1.6

1.8

Jan

yardeni.com

S&P 500 HEALTH CARE FACILITIES RELATIVE VALUATION

P/E Relative to S&P 500*

Relative P/E capped at 1.5 and not availableduring 2007-2009 when earnings were negative.

* Price divided by 12-month forward consensus expected operating earnings per share using mid-month data. Sources for all charts: Standard & Poor’s Corporation, Thomson Financial, and Haver Analytics.

Figure 33.

1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012-50

-25

0

25

50

75

-50

-25

0

25

50

75

Jan

yardeni.com

S&P 500 HEALTH CARE FACILITIES NET REVISIONS*(% estimates up less down)

* Three-month moving average of 12-month forward consensus expected operating earnings per share using mid-month consensus forecast.

Figure 34.

1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012-4

-2

0

2

4

6

8

10

12

-4

-2

0

2

4

6

8

10

12

Q3

yardeni.com

S&P 500 HEALTH CARE FACILITIES PROFIT MARGIN(trailing 4-quarter EPS, percent)

Operating Profit Margin____________________

S&P 500 Composite

Industry

Sources for all charts: Standard & Poor’s Corporation, Thomson Financial, and Haver Analytics.

Figure 35.

- Health Care Facilities -

Page 15 / February 6, 2012 / Analyst’s Handbook: Health Care www.yardeni.com

Yardeni Research, Inc.

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2003 2004 2005 2006 2007 2008 2009 2010 2011 201295

145

195

245

295

345

395

445495545

95

145

195

245

295

345

395

445495545

2/3

yardeni.com

S&P 500 HEALTH CARE SERVICES INDEX*(DGX DVA ESRX LH MHS)

* Ratio scale.

200-day moving average

Figure 36.

2003 2004 2005 2006 2007 2008 2009 2010 2011 20125

15

25

35

45

5

15

25

35

45

Jan

yarden

i.com

S&P 500 HEALTH CARE SERVICES OPERATING EARNINGS PER SHARE(analysts’ average forecasts, ratio scale)

Consensus Forecasts__________________

Annual estimates

12-month forward*

08

09

1011

12

na 9.0 18.1 19.3 21.8 20.4 15.3 20.3 16.7 14.5

* Time-weighted average of current and next year’s consensus earnings estimates. Numbers above time line are annual growth rates.

Figure 37.

2003 2004 2005 2006 2007 2008 2009 2010 2011 20128

10

12

14

16

18

20

22

24

8

10

12

14

16

18

20

22

24

Jan

yardeni.com

S&P 500 HEALTH CARE SERVICES VALUATION

P/E*

S&P 500 P/E*

* Price divided by 12-month forward consensus expected operating earnings per share using mid-month data. Sources for all charts: Standard & Poor’s Corporation, Thomson Financial, and Haver Analytics.

Figure 38.

- Health Care Services -

Page 16 / February 6, 2012 / Analyst’s Handbook: Health Care www.yardeni.com

Yardeni Research, Inc.

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2003 2004 2005 2006 2007 2008 2009 2010 2011 2012.8

.9

1.0

1.1

1.2

1.3

1.4

1.5

1.6

1.7

.8

.9

1.0

1.1

1.2

1.3

1.4

1.5

1.6

1.7

Jan

yardeni.com

S&P 500 HEALTH CARE SERVICES RELATIVE VALUATION

P/E Relative to S&P 500*

* Price divided by 12-month forward consensus expected operating earnings per share using mid-month data. Sources for all charts: Standard & Poor’s Corporation, Thomson Financial, and Haver Analytics.

Figure 39.

2003 2004 2005 2006 2007 2008 2009 2010 2011 2012-30

-20

-10

0

10

20

30

40

50

-30

-20

-10

0

10

20

30

40

50

Jan

yardeni.com

S&P 500 HEALTH CARE SERVICES NET REVISIONS*(% estimates up less down)

* Three-month moving average of 12-month forward consensus expected operating earnings per share using mid-month consensus forecast.

Figure 40.

2003 2004 2005 2006 2007 2008 2009 2010 2011 20122

4

6

8

10

12

2

4

6

8

10

12

Q3

yardeni.com

S&P 500 HEALTH CARE SERVICES PROFIT MARGIN(trailing 4-quarter EPS, percent)

Operating Profit Margin___________________

S&P 500 Composite

Industry

Sources for all charts: Standard & Poor’s Corporation, Thomson Financial, and Haver Analytics.

Figure 41.

- Health Care Services -

Page 17 / February 6, 2012 / Analyst’s Handbook: Health Care www.yardeni.com

Yardeni Research, Inc.

Page 19: Table Of Contents Table Of Contents Table Of …Figure 4. 98 99 00 01 02 03 04 05 06 07 08 09 10 11 12 13 14 100 200 300 400 500 600 700 800 S&P 400 PHARMACEUTICALS_____ 2/3 …

1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 201270

170

270

370

470

570

670

70

170

270

370

470

570

670

2/3

yardeni.com

S&P 500 MANAGED HEALTH CARE INDEX*(AET CI CVH HUM UNH WLP)

* Ratio scale.

200-day moving average

Figure 42.

1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 20124

14

24

34

44

5464

4

14

24

34

44

5464

Jan

yarden

i.com

S&P 500 MANAGED HEALTH CARE OPERATING EARNINGS PER SHARE(analysts’ average forecasts, ratio scale)

Consensus Forecasts__________________

Annual estimates

12-month forward*

0809 10

11 12

10.3 13.4 15.2 -4.2 13.9 21.1 -16.6 55.2 32.4 32.4 21.7 19.0 21.1 -8.6 6.7 22.4 11.1 4.3

* Time-weighted average of current and next year’s consensus earnings estimates. Numbers above time line are annual growth rates.

Figure 43.

1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 20125

10

15

20

25

30

5

10

15

20

25

30

Jan

yardeni.com

S&P 500 MANAGED HEALTH CARE VALUATION

P/E*

S&P 500 P/E*

* Price divided by 12-month forward consensus expected operating earnings per share using mid-month data. Sources for all charts: Standard & Poor’s Corporation, Thomson Financial, and Haver Analytics.

Figure 44.

- Managed Health Care -

Page 18 / February 6, 2012 / Analyst’s Handbook: Health Care www.yardeni.com

Yardeni Research, Inc.

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1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012.4

.6

.8

1.0

1.2

1.4

1.6

.4

.6

.8

1.0

1.2

1.4

1.6

Jan

yardeni.com

S&P 500 MANAGED HEALTH CARE RELATIVE VALUATION

P/E Relative to S&P 500*

* Price divided by 12-month forward consensus expected operating earnings per share using mid-month data. Sources for all charts: Standard & Poor’s Corporation, Thomson Financial, and Haver Analytics.

Figure 45.

1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012-40

-30

-20

-10

0

10

20

30

40

50

-40

-30

-20

-10

0

10

20

30

40

50

Jan

yardeni.com

S&P 500 MANAGED HEALTH CARE NET REVISIONS*(% estimates up less down)

* Three-month moving average of 12-month forward consensus expected operating earnings per share using mid-month consensus forecast.

Figure 46.

1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 20122

3

4

5

6

7

8

9

10

11

12

13

2

3

4

5

6

7

8

9

10

11

12

13

Q3

yardeni.com

S&P 500 MANAGED HEALTH CARE PROFIT MARGIN(trailing 4-quarter EPS, percent)

Operating Profit Margin___________________

S&P 500 Composite

Industry

Sources for all charts: Standard & Poor’s Corporation, Thomson Financial, and Haver Analytics.

Figure 47.

- Managed Health Care -

Page 19 / February 6, 2012 / Analyst’s Handbook: Health Care www.yardeni.com

Yardeni Research, Inc.

Page 21: Table Of Contents Table Of Contents Table Of …Figure 4. 98 99 00 01 02 03 04 05 06 07 08 09 10 11 12 13 14 100 200 300 400 500 600 700 800 S&P 400 PHARMACEUTICALS_____ 2/3 …

1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 201275

150

225

300

375

450

525600

75

150

225

300

375

450

525600

2/3

yardeni.com

S&P 500 PHARMACEUTICALS INDEX*(ABT AGN BMY FRXJNJ KG LLY MRXMYL PFE WPI)

* Ratio scale.

200-day moving average

Figure 48.

1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 20125

10

15

20

25

30

3540

5

10

15

20

25

30

3540

Jan

S&P 500 PHARMACEUTICALS OPERATING EARNINGS PER SHARE(analysts’ average forecasts, ratio scale)

Consensus Forecasts__________________

Annual estimates

yarden

i.com

12-month forward*

08

09 10 1112

10.3 16.3 13.3 15.7 14.9 12.9 11.5 1.1 8.4 9.1 2.6 3.8 13.0 8.0 -3.9 8.0 4.6 0.5

* Time-weighted average of current and next year’s consensus earnings estimates. Numbers above time line are annual growth rates.

Figure 49.

1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 20125

10

15

20

25

30

35

40

5

10

15

20

25

30

35

40

Jan

yardeni.com

S&P 500 PHARMACEUTICALS VALUATION

P/E*

S&P 500 P/E*

* Price divided by 12-month forward consensus expected operating earnings per share using mid-month data. Sources for all charts: Standard & Poor’s Corporation, Thomson Financial, and Haver Analytics.

Figure 50.

- Pharmaceuticals -

Page 20 / February 6, 2012 / Analyst’s Handbook: Health Care www.yardeni.com

Yardeni Research, Inc.

Page 22: Table Of Contents Table Of Contents Table Of …Figure 4. 98 99 00 01 02 03 04 05 06 07 08 09 10 11 12 13 14 100 200 300 400 500 600 700 800 S&P 400 PHARMACEUTICALS_____ 2/3 …

1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012.6

.8

1.0

1.2

1.4

1.6

1.8

.6

.8

1.0

1.2

1.4

1.6

1.8

Jan

yardeni.com

S&P 500 PHARMACEUTICALS RELATIVE VALUATION

P/E Relative to S&P 500*

* Price divided by 12-month forward consensus expected operating earnings per share using mid-month data. Sources for all charts: Standard & Poor’s Corporation, Thomson Financial, and Haver Analytics.

Figure 51.

1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012-25

-20

-15

-10

-5

0

5

10

15

20

25

-25

-20

-15

-10

-5

0

5

10

15

20

25

Jan

yardeni.com

S&P 500 PHARMACEUTICALS NET REVISIONS*(% estimates up less down)

* Three-month moving average of 12-month forward consensus expected operating earnings per share using mid-month consensus forecast.

Figure 52.

1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 20125

10

15

20

25

5

10

15

20

25

Q3

yardeni.com

S&P 500 PHARMACEUTICALS PROFIT MARGIN(trailing 4-quarter EPS, percent)

Operating Profit Margin___________________

S&P 500 Composite

Industry

Sources for all charts: Standard & Poor’s Corporation, Thomson Financial, and Haver Analytics.

Figure 53.

- Pharmaceuticals -

Page 21 / February 6, 2012 / Analyst’s Handbook: Health Care www.yardeni.com

Yardeni Research, Inc.

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1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 20130

100

200

300

400

500

600

700

800

900

1000

1100

0

100

200

300

400

500

600

700

800

900

1000

1100

Jan

S&P 500 FORWARD EARNINGS:*HEALTH CARE(1997=100)

Health Care

Biotechnology

Health Care Equipment

Managed Health Care

* 12-month forward consensus expected operating earnings per share. Time-weighted average of current and next year’sconsensus forecasts.Source: Thomson Financial.

yardeni.com

Figure 54.

1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 20130

5

10

15

20

25

30

35

40

45

50

55

60

65

70

0

5

10

15

20

25

30

35

40

45

50

55

60

65

70

Jan

S&P 500 P/E RATIOS:*HEALTH CARE

Health Care

Biotechnology

Health Care Equipment

Managed Health Care

* Price divided by 12-month forward consensus expected operating earnings per share using mid-month data.Source: Thomson Financial.

yardeni.com

Figure 55.

- Relative Earnings & P/E: Health Care -

Page 22 / February 6, 2012 / Analyst’s Handbook: Health Care www.yardeni.com

Yardeni Research, Inc.

Page 24: Table Of Contents Table Of Contents Table Of …Figure 4. 98 99 00 01 02 03 04 05 06 07 08 09 10 11 12 13 14 100 200 300 400 500 600 700 800 S&P 400 PHARMACEUTICALS_____ 2/3 …

1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013-50

0

50

100

150

200

250

300

350

400

-50

0

50

100

150

200

250

300

350

400

JanS&P 500 FORWARD EARNINGS:*HEALTH CARE(1997=100)

Health Care

Health Care Facilities

Pharmaceuticals

Health CareDistributors

* 12-month forward consensus expected operating earnings per share. Time-weighted average of current and next year’sconsensus forecasts.Source: Thomson Financial.

yardeni.com

Figure 56.

1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 20135

10

15

20

25

30

35

40

45

5

10

15

20

25

30

35

40

45

Jan

S&P 500 P/E RATIOS:*HEALTH CARE

Health Care

Health Care Facilities(P/E capped at 40)Pharmaceuticals

Health Care Distributors

* Price divided by 12-month forward consensus expected operating earnings per share using mid-month data.Source: Thomson Financial.

yardeni.com

Figure 57.

- Relative Earnings & P/E: Health Care -

Page 23 / February 6, 2012 / Analyst’s Handbook: Health Care www.yardeni.com

Yardeni Research, Inc.

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1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 20120

2

4

6

8

10

12

14

16

18

20

22

24

26

28

30

32

34

36

38

0

2

4

6

8

10

12

14

16

18

20

22

24

26

28

30

32

34

36

38

Q3

S&P 500 OPERATING PROFIT MARGINS: HEALTH CARE(trailing 4-quarter EPS, percent)

Health Care Sector

Biotechnology

Health Care Equipment

Managed Health Care

Sources for all charts: Standard & Poor’s Corporation, Thomson Financial, and Haver Analytics.

yardeni.com

Figure 58.

1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012-4

-2

0

2

4

6

8

10

12

14

16

18

20

22

24

26

-4

-2

0

2

4

6

8

10

12

14

16

18

20

22

24

26

Q3

S&P 500 OPERATING PROFIT MARGINS: HEALTH CARE(trailing 4-quarter EPS, percent)

Health Care Sector

Health Care Facilities

Pharmaceuticals

Health Care Distributors

Sources for all charts: Standard & Poor’s Corporation, Thomson Financial, and Haver Analytics.

yardeni.com

Figure 59.

- Profit Margin -

Page 24 / February 6, 2012 / Analyst’s Handbook: Health Care www.yardeni.com

Yardeni Research, Inc.

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Figure 66.

1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014-5

0

5

10

15

20

25

30

35

-5

0

5

10

15

20

25

30

35

Jan

S&P 500 HEALTH CARE vs. S&P 500(percent)

STEG*_____

S&P 500 Health CareS&P 500

1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 20125

10

15

20

5

10

15

20

Jan

LTEG*_____

S&P 500 Health CareS&P 500

1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014-5

0

5

10

15

20

-5

0

5

10

15

20

Jan

S&P 500 Health Care__________________

STEG*

LTEG*

yardeni.com

* Short-term earnings growth: 12-month forward consensus expected earnings growth. Long-term earnings growth: 5-year forward consensus expected earnings growth.Source: Thomson Financial.

- Earnings Growth -

Page 25 / February 6, 2012 / Analyst’s Handbook: Health Care www.yardeni.com

Yardeni Research, Inc.

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Figure 67.

1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014-20

-15

-10

-5

0

5

10

-20

-15

-10

-5

0

5

10

Jan

S&P 500 HEALTH CARE VS S&P 500(percentage points)

Health Care Less S&P 500 STEG*

1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014-5

-4

-3

-2

-1

0

1

2

3

-5

-4

-3

-2

-1

0

1

2

3

Jan

Health Care LessS&P 500 LTEG*

1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014-7

-6

-5

-4

-3

-2

-1

0

1

2

3

-7

-6

-5

-4

-3

-2

-1

0

1

2

3

JanHealth Care STEG*Less Health Care LTEG*

yardeni.com

* Short-term earnings growth: 12-month forward consensus expected earnings growth. Long-term earnings growth: 5-year forward consensus expected earnings growth.Source: Thomson Financial.

- Earnings Growth Spreads -

Page 26 / February 6, 2012 / Analyst’s Handbook: Health Care www.yardeni.com

Yardeni Research, Inc.

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90 91 92 93 94 95 96 97 98 99 00 01 02 03 04 05 06 07 08 09 10 11 120

1

2

3

4

5

6

7

8

9

10

11

12

0

1

2

3

4

5

6

7

8

9

10

11

12

Dec

CONSUMER PRICES(yearly percent change)

Prescription Drugs_______________

CPI

PCED*

* Personal consumption expenditures deflator.Source: US Department of Commerce, Bureau of Economic Analysis and US Department of Labor,Bureau of Labor Statistics.

yardeni.com

Figure 68.

- Pricing -

Page 27 / February 6, 2012 / Analyst’s Handbook: Health Care www.yardeni.com

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