VOL 28, NO 3 June 2013

CONTENTSEditorial

Technology Application: Disruptive, Empowering, Controlling? Philip D. Lumb....................................................................................................................... 221

Cognitive Function and Delirium in the ICU

Delirium Assessment Using Confusion Assessment Method for the Intensive Care Unit in Chinese Critically Ill Patients

Chunli Wang, Ying Wu, Peng Yue, E. Wesley Ely, Jie Huang, Xin Yang, and Yisi Liu ............ 223

Vitamin D and Delirium in Critically Ill Patients: A Preliminary InvestigationAlessandro Morandi, Nicolas Barnett, Russel R. Miller III, Timothy D. Girard, Pratik P. Pandharipande, Eugene W. Ely, and L.B. Ware ....................................................... 230

Perioperative Plasma Melatonin Concentration in Postoperative Critically Ill Patients: Its Association With Delirium

Shiho Yoshitaka, Moritoki Egi, Hiroshi Morimatsu, Tomoyuki Kanazawa, Yuichiro Toda, and Kiyoshi Morita. ....................................................................................... 236

Epidemiology, Quality Improvement and Outcome

Drug-Drug Interactions Contributing to QT Prolongation in Cardiac Intensive Care UnitsMichael J. Armahizer, Amy L. Seybert, Pamela L. Smithburger, and Sandra L. Kane-Gill ....................................................................................................... 243

Risk of in-Hospital Mortality Identified According to the Typology of Patients With Acute Heart Failure: Classification Tree Analysis on Data From the Acute Heart Failure Database–Main Registry

Daniela Tomcikova, Marian Felsoci, Jindrich Spinar, Roman Miklik, Tereza Mikusova, Jiri Vitovec, Lenka Spinarova, Petr Widimsky, Ales Linhart, Jan Belohlavek, Marian Fedorco, Cestmir Cihalik, Filip Malek, Miroslav Bambuch, Jan Vaclavik, Jiri Kettner, Jiri Jarkovsky, Ladislav Dusek, and Jiri Parenica ...................... 250

A Structured Educational Intervention to Improve Targeted Temperature Management Utilization After Cardiac Arrest

Audrey L. Blewer, Gail Delfin, Marion Leary, David F. Gaieski, and Benjamin S. Abella.......................................................................................................... 259

Cardiac Output Responses in a Flow-Driven Protocol of Resuscitation Following Cardiac SurgeryBrian J. Potter, Benoit Deverenne, Steve Doucette, Dean Fergusson, and Sheldon Magder .............................................................................................................. 265

Journal ofCritical Care

Cerebral Desaturation Events in the Intensive Care Unit Following Cardiac SurgerySteven B. Greenberg, Glenn Murphy, John Alexander, Renee Fasanella, Andrea Garcia, and Jeffery Vender ........................................................................................ 270

Clinical Epidemiology of Central Venous Catheter–Related Bloodstream Infections in an Intensive Care Unit in China

Songlin Peng and Yan Lu ....................................................................................................... 277

Sepsis

Improving the 2007 Infectious Disease Society of America/American Thoracic Society Severe Community-Acquired Pneumonia Criteria to Predict Intensive Care Unit Admission

Oriol Sibila, G. Umberto Meduri, Eric M. Mortensen, Antonio Anzueto, Elena Laserna, Juan F. Fernandez, Ali El-Sohl, Marcos I. Restrepo .................................... 284

Impact of Serum C-Reactive Protein Measurements in the First 2 Days on the 30-Day Mortality in Hospitalized Patients With Severe Community-Acquired Pneumonia: A Cohort Study

William Nseir, Raymond Farah, Julnar Mograbi, and Nicola Makhoul ................................... 291

Assessment of the Safety and Feasibility of Administering Antipyretic Therapy in Critically Ill Adults: A Pilot Randomized Clinical Trial

Daniel J. Niven, H. Tom Stelfox, Caroline Léger, Paul Kubes, and Kevin B. Laupland ........... 296

Antipyretic Therapy in Febrile Critically Ill Adults: A Systematic Review and Meta-AnalysisDaniel J. Niven, H. Tom Stelfox, and Kevin B. Laupland ...................................................... 303

Letters/Editorials

Effects of Associated Factors With Acute Lung Injury in Combat CasualtiesBrian L. Dixon and L. Lee Glenn .......................................................................................... 311

The Effect of Warmed Fresh Whole Blood and Acute Lung Injury in Combat CasualtiesChee M. Chan, Andrew F. Shorr, and Jeremy G. Perkins ...................................................... 312

Renal Doppler in the Management of the Acute Kidney Injury in Intensive Care UnitSchaal Jean-Vivien, Pasquier Pierre, Renner Julie, Jarrassier Audrey, Salvadori Alexandre, and Mérat Stéphane ............................................................................ 313

Renal Doppler in the Management of the Acute Kidney Injury in Intensive Care UnitAntoine Dewitte ...................................................................................................................... 314

Electronic Articles

Contributions of Tele–Intensive Care Unit (Tele-ICU) Technology to Quality of Care and Patient Safety

Adjhaporn Khunlertkit and Pascale Carayon ....................................................................... 315

Motivation and Job Satisfaction of Tele-ICU NursesPeter L.T. Hoonakker, Pascale Carayon, Kerry McGuire, Adjhaporn Khunlertkit, Douglas A. Wiegmann, Bashar Alyousef, Anping Xie, and Kenneth E. Wood. ...................... 315

Full Outline of UnResponsiveness Score and Glasgow Coma Scale in Medical Patients With Altered Sensorium: Interrater Reliability and Relation to Outcome

Arunodaya R. Gujjar, Poovathru C. Jacob, R. Nandhagopal, S.S. Ganguly, Ammar Obaidy, and Abdullah R. Al-Asmi ............................................................................. 316

Nonpharmacologic Interventions for Prevention of Catheter-Related Thrombosis: A Systematic Review

Matthew D. Mitchell, Rajender Agarwal, Todd E.H. Hecht, and Craig A. Umscheid .......... 316

Journal of Critical Care now features Articles in Press!

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Consecutive Thrombelastography Clot Strength Profiles in Patients With Severe Sepsis and Their Association With 28-Day Mortality: A Prospective Study

Sisse R. Ostrowski, Nis A. Windeløv, Michael Ibsen, Nicolai Haase, Anders Perner, and Pär I. Johansson ............................................................................................................. 317

Simplistic Approach to Prognosis After Cardiopulmonary Resuscitation—Value of pH and Lactate

Florian H. Seeger, Moritz Toenne, Ralf Lehmann, and Joachim R. Ehrlich ......................... 317

Effect of Pulse Pressure on the Predictability of Stroke Volume Variation for Fluid Responsiveness in Patients With Coronary Disease

So Yeon Kim, Young Song, Jae Kwang Shim, and Young Lan Kwak ..................................... 318

A Conceptual Approach to Improving Care in Pandemics and Beyond: Severe Lung Injury Centers

Amesh A. Adalja, Matthew Watson, Richard E. Waldhorn, and Eric S. Toner ...................... 318