7/27/2019 Table 601. Drugs with Significant Adverse Effects on the Fetus.

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7/27/2019 Table 601. Drugs with Significant Adverse Effects on the Fetus.

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Drug Trimester Effect

enicillaine First #utis la3a$ other congenital alforations

henc&clidine All Abnoral neurologic e3aination$ %oor suc refle3and feeding

hen&toin All Fetal h&dantoin s&ndroero%&lthiouracil All #ongenital goiter

Stre%to&cin All Eighth nerve to3icit& described in a few cases

Soing(constituentsof tobacco soe"

All /ntrauterine growth retardation- %reaturit&- suddeninfant death s&ndroe- %erinatal co%lications

Tao3ifen All /ncreased ris of s%ontaneous abortion or fetaldaage

Tetrac&cline All Discoloration and defects of teeth

Thalidoide First hocoelia (shortened or absent long bones of thelibs" and an& internal alforations

Triethadione All )ulti%le congenital anoalies,al%roic acid All *eural tube defects

9arfarin First 2&%o%lastic nasal bridge$ chondrod&s%lasia

Second #*S alforations

Third 'is of bleeding. Discontinue use 1 onth beforedeliver&