664 FAMILY VI. STREPTOCOCCACEAE

TAB

LE 1

31.

Ch

arac

teri

stic

s of

Str

epto

cocc

us s

peci

esa

Cha

ract

eris

tic

S. pyogenes

S. acidominimus

b

S. agalactiae

S. alactolyticus

S. anginosus

S. australis

S. canis

S. constellatus subsp.

constellatus

S. constellatus subsp.

pharyngis

S. criceti

S. cristatus

S. devriesei

S. didelphis

Cel

l siz

e (m

) 0.

51.

0 N

D

0.6

1.2

0.5

1.0

0.5

1.0

ND

N

D

0.5

1.0

0.5

1.0

0.5

~1.0

N

D

ND

C

atal

ase

+c

Acid

pro

duct

ion

from

:

N-

Ace

tyl-g

luco

sam

ine

+ N

D

+ +

d N

D

+ +

+ +

+

ND

Ado

nito

l

N

D

ND

ND

N

D

ND

N

D

N

D

A

myg

dalin

ND

d +

ND

d +

+

+ N

D

A

rabi

nose

A

rbut

in

N

D

d

+ N

D

+ d

+ +

+ +

ND

Ara

bito

l

N

D

ND

ND

N

D

ND

N

D

e

ND

Cel

lobi

ose

d N

D

d +

d N

D

ND

d

ND

+

ND

+

ND

Cyc

lode

xtrin

ND

N

D

ND

N

D

ND

ND

Dex

tran

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

Dul

cito

l

N

D

ND

ND

N

D

ND

N

D

d N

D

Er

ythr

itol

ND

N

D

N

D

ND

N

D

ND

ND

Escu

lin

ND

N

D

N

D

ND

N

D

ND

N

D

ND

N

D

ND

+

ND

Fruc

tose

+

+ +

+ N

D

ND

+

ND

N

D

ND

N

D

+ N

D

Fu

cose

N

D

N

D

N

D

ND

ND

N

D

ND

N

D

N

D

G

alac

tose

+

ND

+

+ N

D

ND

+

ND

N

D

+ d

+ N

D

G

entio

bios

e N

D

ND

N

D

d N

D

ND

ND

N

D

ND

N

D

+ N

D

G

luco

nate

N

D

ND

ND

N

D

ND

N

D

+ N

D

2-

Ket

oglu

cona

te

ND

ND

ND

N

D

N

D

ND

N

D

ND

ND

5-K

etog

luco

nate

N

D

N

D

N

D

ND

N

D

ND

N

D

ND

N

D

N

D

G

luco

se

+ +

+ +

+ N

D

+ +

+ +

ND

+

ND

Gly

cero

l d

ND

+

d

ND

N

D

N

D

N

D

G

lyco

gen

d

g

N

D

N

D

In

osito

l N

D

N

D

N

D

ND

ND

N

D

ND

N

D

N

D

In

ulin

N

D

+

ND

+

d

La

ctos

e +

+ d

+

+ +

d +

d d

+ d

Ly

xose

N

D

N

D

N

D

ND

N

D

ND

N

D

ND

N

D

N

D

M

alto

se

+ N

D

+ +

+ +

+ +

ND

+

+ +

ND

Man

nose

N

D

ND

N

D

+ N

D

ND

+

ND

N

D

ND

N

D

+ N

D

M

anni

tol

+

dh

()

dh (

)

+

+

Mel

ibio

se

N

D

d

d

+

+

ND

Mel

ezito

se

N

D

d

ND

N

D

ND

ND

Met

hyl-D

-man

nosi

de

ND

N

D

N

D

ND

N

D

ND

ND

Met

hyl-D

-glu

cosi

de

+

+ d

+

d d

ND

ND

+

ND

-Met

hylx

ylos

ide

ND

N

D

ND

N

D

ND

N

D

N

D

ND

N

D

ND

ND

Met

hyl-D

-xyl

osid

e

d

N

D

ND

ND

N

D

ND

N

D

N

D

Pu

llula

n d

+

d

+ N

D

N

D

ND

d

N

D

R

affin

ose

N

D

+ d

+

+ d

R

ham

nose

N

D

N

D

N

D

ND

ND

N

D

N

D

R

ibos

e

+

+

N

D

+

Sa

licin

+

ND

d

d +

ND

+

ND

N

D

+ N

D

+

So

rbito

l

+

+

So

rbos

e

N

D

ND

ND

N

D

d N

D

St

arch

N

D

N

D

d N

D

ND

+

ND

N

D

N

D

ND

d

Su

cros

e +

+ +

+ +

+ +

ND

N

D

+ N

D

+ N

D

Ta

gato

se

N

D

d

ND

N

D

+

ND

Treh

alos

e +

+

d +

d

d +

d +

+ +

D

-Tur

anos

e N

D

N

D

d N

D

ND

ND

N

D

ND

N

D

X

ylos

e

N

D

ND

ND

N

D

N

D

N

D

X

ylito

l N

D

N

D

N

D

ND

ND

N

D

ND

N

D

Hyd

roly

sis o

f:

Arg

inin

e +

+

+

+ +

+ +

dh

(+)

dh

(+)

Es

culin

d

+

+ +

ND

+

+ +

dh (+

)

ND

G

elat

in

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

GENUS I. STREPTOCOCCUS 665

(con

tin

ued)

Hip

pura

te

+h

, m (

) +

N

D

+ +h

()

St

arch

ND

ND

ND

N

D

ND

Prod

uctio

n of

:o

A

cid

phos

phat

ase

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

Alk

alin

e ph

osph

atas

e +

+

+

+ +

+ +

ND

+

-L

-Ara

bino

sida

se

ND

N

D

ND

N

D

N

D

ND

N

D

ND

N

D

ND

N

D

ND

-D-G

alac

tosi

dase

ND

d

+

d

ND

+ d

-D

-Gal

acto

sida

se

N

D

d

p +

+

ND

d

Ph

osph

o--g

alac

tosi

dase

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

-D

-Glu

cosi

dase

N

D

ND

N

D

ND

d

ND

N

D

+ +

ND

ND

N

D

-D

-Glu

cosi

dase

ND

d

+

ND

+ N

D

+

-L-F

ucos

idas

e N

D

ND

N

D

ND

ND

N

D

ND

+

ND

N

D

-D

-Fuc

osid

ase

ND

N

D

ND

N

D

N

D

ND

+ N

D

N

D

ND

-L-F

ucos

idas

e N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

-D

-Glu

curo

nida

se

d +

d

d

N

D

ND

+

-Glu

cosa

min

idas

e N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

N-

Ace

tyl-

-D-g

alac

tosa

min

idas

e N

D

ND

N

D

ND

ND

N

D

+

ND

+

ND

N

D

N-

Ace

tyl-

-D-g

luco

sam

inid

ase

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N-A

cety

l--D

-glu

cosa

min

idas

e

p

ND

d N

D

+ N

D

ND

-Mal

tosi

dase

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

-M

alto

sida

se

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

Gly

cyl-t

rypt

opha

n ar

ylam

idas

e

+ N

D

ND

N

D

ND

N

D

N

D

-D

-Lac

tosi

dase

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

Le

ucin

e ar

ylam

idas

e N

D

ND

+ +

ND

+

+ +

ND

N

D

ND

+

Le

ucin

e am

inop

eptid

ase

ND

+

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

Lysi

ne d

ecar

boxy

lase

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

-D

-Man

nosi

dase

N

D

ND

N

D

ND

ND

N

D

N

D

ND

N

D

ND

N

D

-M

anno

sida

se

ND

ND

N

D

ND

+k

N

D

O

rnith

ine

deca

rbox

ylas

e N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

Ph

osph

oam

idas

e N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

Py

rogl

utam

ic a

cid

aryl

amid

ase

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

ND

Pyro

lidon

ylar

ylam

idas

e +

+

ND

N

D

ND

Si

alid

ase

(neu

ram

inid

ase)

d

ND

+

ND

s

ND

N

D

N

D

ND

Ala

-phe

-pro

ary

lam

idas

et N

D

+ N

D

ND

N

D

+ N

D

ND

N

D

ND

N

D

+ N

D

-X

ylos

idas

e N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

-D

-Xyl

osid

ase

ND

N

D

ND

N

D

N

D

ND

ND

N

D

ND

N

D

ND

Chy

mot

ryps

in

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

Hya

luro

nida

se

+ N

D

d N

D

N

D

d

d N

D

N

D

ND

Ure

ase

+h

()

ND

ND

Val

ine

amin

opep

tidas

e N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

A

ceto

in (V

P)

+ h,

u ()

+

+

+

+ +

+

H

2O2

ND

N

D

ND

N

D

d N

D

ND

ND

+ N

D

ND

IgA

1 pr

otea

se

ND

N

D

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

Extra

cellu

lar p

olys

acch

arid

e N

D

ND

N

D

+ d

ND

N

D

Am

ylas

e bi

ndin

g N

D

ND

N

D

ND

d N

D

N

D

ND

+

ND

N

D

CA

MP

reac

tion

N

D

+ N

D

N

D

h (

+)

ND

N

D

ND

Gro

wth

at:

10C

d

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

45

C

+

ND

N

D

ND

N

D

ND

ND

N

D

ND

G

rowt

h in

pre

senc

e of

:

6.

5% w

/w N

aCl

d

ND

N

D

N

D

ND

N

D

ND

N

D

ND

40%

bile

ND

d

N

D

ND

ND

N

D

ND

N

D

ND

N

D

pH

9.6

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

Hem

olyt

ic R

eact

ion

(,

) ,N

H

NH

,,

,,N

H

N

H,

La

ncef

ield

gro

up a

ntig

en

A

NG

B

D

(G)

NG

, F, C

, G, A

N

G

G

NG

, F, C

, G, A

C

N

G

ND

N

D

NG

Pe

ptid

ogly

can

type

x Ly

sA

la1

3 Ly

sSe

rG

ly

Lys

Ala

13 (

Ser)

N

D

Lys

Ala

13

Lys

Ala

Gly

Ly

sTh

rG

ly

Lys

Ala

13

ND

Ly

sTh

rA

la

ND

N

D

ND

M

ajor

cel

l-wal

l car

bohy

drat

e co

nstit

uent

sz

Rha

, Glc

NA

c R

ha, G

al, (

Glc

NA

c)

Rha

, Gal

, Glc

NA

c , G

luci

tol

ND

R

ha, G

lc, G

al, G

alN

Ac

ND

N

D

Rha

, Glc

, Gal

, Glc

NA

c N

D

Rha

, Glc

, Gal

N

D

ND

N

D

Hos

t M

an

Cat

tle, m

ilk

Man

, ani

mal

s A

nim

als

Man

M

an

Ani

mal

s, m

an

Man

M

an

Ani

mal

s (m

an)aa

M

an

Ani

mal

s A

nim

als

Sour

ce o

f dat

aab

19, 2

6, 2

7, 4

0 16

, 19,

40

19, 2

6 23

, 35,

47

1, 2

7, 3

8, 5

1, 5

2, 5

5 58

13

, 19

27, 5

1, 5

4, 5

5 27

, 51,

54,

55

4, 1

2, 2

7, 3

3 25

, 27

62

38

666 FAMILY VI. STREPTOCOCCACEAE

TAB

LE 1

31.

(con

tin

ued)

Char

acte

ristic

S. downei

S. dysgalactiae subsp.

dysgalactiae

S. dysgalactiae subsp.

equisimilis

S. entericus

S. equi subsp. equi

S. equi subsp.

zooepidemicus

S. equinus

S. ferus

S. gallinaceus

S. gallolyticus subsp.

gallolyticus

S. gallolyticus subsp.

macedonicus

S. gordonii

S. hyointestinalis

S. hyovaginalis

S. infantarius

Cel

l siz

e (m

) N

D

ND

N

D

ND

N

D

ND

N

D

0.5

ND

N

D

ND

N

D

ND

N

D

ND

C

atal

ase

Ac

id p

rodu

ctio

n fro

m:

N-A

cety

l-glu

cosa

min

e N

D

ND

N

D

ND

N

D

ND

+

+ N

D

ND

+

+ +

+ N

D

A

doni

tol

ND

N

D

ND

N

D

ND

N

D

ND

ND

N

D

A

myg

dalin

N

D

ND

N

D

ND

N

D

ND

+

+ N

D

+

+ d

N

D

A

rabi

nose

ND

A

rbut

in

ND

N

D

ND

N

D

ND

N

D

+ d

ND

N

D

d +

+ N

D

ND

Ara

bito

l N

D

ND

N

D

N

D

ND

ND

C

ello

bios

e

ND

N

D

ND

N

D

ND

+

+ N

D

ND

+

+ d

+ N

D

C

yclo

dext

rin

ND

N

D

ND

+

ND

N

D

N

D

ND

N

D

Dex

tran

ND

N

D

ND

N

D

ND

N

D

N

D

ND

N

D

ND

N

D

ND

N

D

ND

Dul

cito

l N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

Er

ythr

itol

ND

N

D

ND

N

D

ND

N

D

ND

N

D

N

D

ND

Escu

lin

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

+

ND

N

D

ND

Fruc

tose

+

ND

N

D

ND

N

D

ND

+

+ N

D

ND

+

+ +

+ N

D

Fu

cose

N

D

ND

N

D

ND

N

D

ND

N

D

ND

ND

N

D

G

alac

tose

+

ND

N

D

ND

N

D

ND

+

+ N

D

ND

+

+ +

+ N

D

G

entio

bios

e N

D

ND

N

D

ND

N

D

ND

d

ND

N

D

ND

ND

d

N

D

G

luco

nate

N

D

ND

N

D

ND

N

D

ND

ND

N

D

ND

N

D

2-

Ket

oglu

cona

te

ND

N

D

ND

N

D

ND

N

D

ND

N

D

N

D

ND

5-K

etog

luco

nate

N

D

ND

N

D

ND

N

D

ND

N

D

ND

ND

N

D

G

luco

se

+ +

+ N

D

+ +

+ +

+ N

D

+ +

+ +

ND

Gly

cero

l

d d

ND

N

D

ND

d

N

D

G

lyco

gen

d +

+ +

d +

+

d

Inos

itol

N

D

ND

N

D

ND

N

D

ND

N

D

N

D

ND

Inul

in

+

d d

ND

d

d

Lact

ose

+ d

d +

+

d +

+ +

+ +

+ +

+

Lyxo

se

ND

N

D

ND

N

D

ND

N

D

ND

N

D

N

D

ND

Mal

tose

+

+ +

+ +

+ +

+ +

+ +

+ +

+ +

M

anno

se

+ N

D

ND

N

D

ND

N

D

+ +

ND

N

D

+ +

+ +

ND

Man

nito

l +

d

dh (+

) +

+

+

M

elib

iose

ND

N

D

N

D

ND

dh

()

d +

h (

+)

ND

d

ND

dh (+

)

Mel

ezito

se

ND

N

D

ND

ND

Met

hyl-D

-man

nosi

de

ND

N

D

ND

N

D

ND

N

D

ND

ND

N

D

ND

N

D

ND

Met

hyl-D

-glu

cosi

de

ND

N

D

ND

+

+ +

d

+ +

d d

d

-Met

hylx

ylos

ide

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

N

D

ND

ND

Met

hyl-D

-xyl

osid

e N

D

ND

N

D

ND

N

D

ND

ND

N

D

ND

ND

N

D

Pu

llula

n

ND

N

D

+

+

ND

+

d

d

Raf

finos

e

d

d +

d +

d d

d

R

ham

nose

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

R

ibos

e N

D

+ +

+

+

d

Sa

licin

+

ND

N

D

ND

+

+ +

+ N

D

ND

d

+ +

+ N

D

So

rbito

l

h (+)

d

+

dh

(+)

h (

d)

+

Sorb

ose

d

ND

N

D

ND

N

D

ND

N

D

ND

Star

ch

+

+ +

+ +

d +

ND

+

d

+

d

Sucr

ose

+ +

+ +

+ +

+ +

+ +

+ +

+ +

+

Taga

tose

N

D

ND

N

D

d

Tr

ehal

ose

+ +

+ +

d

d +

+ +

+

+ +

D-T

uran

ose

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

Xyl

ose

ND

N

D

ND

N

D

N

D

ND

Xyl

itol

N

D

ND

N

D

ND

N

D

ND

N

D

ND

H

ydro

lysi

s of:

A

rgin

ine

+

+

+ +

+

+

Escu

lin

d

dh (+

) +

d d

+ +

+ +

+

+h (

)

d

Gel

atin

N

D

ND

N

D

ND

ND

ND

N

D

ND

ND

N

D

GENUS I. STREPTOCOCCUS 667

(con

tin

ued)

Hip

pura

te

dh (

)

+

Star

ch

N

D

+ +

+

ND

+

d

+n

ND

+

Prod

uctio

n of

:o

A

cid

phos

phat

ase

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

+

ND

ND

Alk

alin

e ph

osph

atas

e

+ +

+

+

d

+ +

+

-L

-Ara

bino

sida

se

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

ND

N

D

ND

-D-G

alac

tosi

dase

N

D

d

d +

d d

d d

+

-D

-Gal

acto

sida

se

ND

+ +

+ d

d d

+

Phos

pho-

-gal

acto

sida

se

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

+

ND

N

D

ND

-D-G

luco

sida

se

ND

N

D

ND

N

D

ND

N

D

ND

+

+ N

D

d d

ND

N

D

ND

-D-G

luco

sida

se

ND

N

D

ND

+

+ +

+ +

+

ND

d

d

-L-F

ucos

idas

e N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

+ N

D

ND

N

D

-D

-Fuc

osid

ase

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

ND

N

D

ND

-L-F

ucos

idas

e N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

N

D

ND

N

D

-D

-Glu

curo

nida

se

ND

+

+

+ +

+

-Glu

cosa

min

idas

e N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

+ N

D

ND

N

D

N-

Ace

tyl-

-D-g

alac

tosa

min

idas

e N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

d N

D

ND

N

D

N-

Ace

tyl-

-D-g

luco

sam

inid

ase

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

ND

N

D

ND

N-A

cety

l--D

-glu

cosa

min

idas

e N

D

ND

N

D

ND

+ N

D

+q

-Mal

tosi

dase

N

D

ND

N

D

ND

N

D

ND

N

D

+ N

D

ND

N

D

+ N

D

ND

N

D

-M

alto

sida

se

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

ND

N

D

ND

Gly

cyl-t

rypt

opha

n ar

ylam

idas

e N

D

ND

N

D

+ N

D

ND

ND

+

ND

d N

D

-D

-Lac

tosi

dase

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

+ N

D

ND

N

D

Le

ucin

e ar

ylam

idas

e N

D

+ +

+ +

+ +

+ N

D

+ +

ND

+

+r

+

Leuc

ine

amin

opep

tidas

e N

D

ND

N

D

ND

N

D

ND

+

ND

N

D

ND

N

D

+ N

D

ND

N

D

Ly

sine

dec

arbo

xyla

se

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

-D-M

anno

sida

se

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

ND

N

D

ND

-Man

nosi

dase

N

D

N

D

ND

d

ND

d

+ N

D

O

rnith

ine

deca

rbox

ylas

e N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

Ph

osph

oam

idas

e N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

d N

D

ND

N

D

Py

rogl

utam

ic a

cid

aryl

amid

ase

ND

N

D

ND

ND

N

D

ND

N

D

N

D

ND

N

D

ND

N

D

ND

Pyro

lidon

ylar

ylam

idas

e N

D

d

N

D

Si

alid

ase

(neu

ram

inid

ase)

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

N

D

ND

N

D

A

la-p

he-p

ro a

ryla

mid

aset

ND

N

D

ND

+

ND

N

D

+ N

D

+ +

+ +

ND

+

+

-Xyl

osid

ase

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

ND

N

D

ND

-D-X

ylos

idas

e N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

N

D

ND

N

D

C

hym

otry

psin

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

+ N

D

ND

N

D

H

yalu

roni

dase

N

D

+ +

ND

+

+ N

D

ND

N

D

ND

N

D

ND

N

D

U

reas

e

ND

N

D

V

alin

e am

inop

eptid

ase

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

+

ND

N

D

ND

Ace

toin

(VP

) +

+

+

+ +

+

+ +

H

2O2

N

D

ND

N

D

ND

N

D

ND

ND

N

D

ND

+

ND

N

D

ND

IgA

1 pr

otea

se

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

ND

N

D

ND

Extra

cellu

lar p

olys

acch

arid

e +

ND

N

D

ND

N

D

ND

+ N

D

+ N

D

+

ND

Am

ylas

e bi

ndin

g N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

+ N

D

ND

N

D

CA

MP

reac

tion

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

G

rowt

h at

:

10

C

ND

ND

+

N

D

ND

N

D

ND

45C

+

ND

N

D

+ +

ND

N

D

ND

N

D

Gro

wth

in p

rese

nce

of:

6.5%

w/w

NaC

l

N

D

d

40

% b

ile

d N

D

ND

N

D

+ N

D

ND

N

D

ND

N

D

N

D

ND

pH 9

.6

+

N

D

ND

N

D

ND

N

D

ND

N

D

ND

H

emol

ytic

Rea

ctio

n N

D

,NH

NH

, N

H

,NH

La

ncef

ield

gro

up a

ntig

en

NG

C

C

, G, L

, A

D

C

C

D

NG

D

, NG

D

, NG

D

, NG

N

G, H

N

G

NG

N

G, D

Pe

ptid

ogly

can

type

x Ly

sTh

rA

la

Lys

Ala

13

Lys

Ala

13

ND

Ly

sA

la1

3 Ly

sA

la2

3 Ly

sTh

rA

la

Lys

Ala

23

ND

N

D

ND

Ly

sA

la1

3 Ly

sA

la (S

er)

ND

N

D

Maj

or c

ell-w

all c

arbo

hydr

ate

cons

titue

ntsz

N

D

Rha

, Gal

NA

c N

D

ND

R

ha, G

alN

Ac

ND

N

D

Rha

, Glc

N

D

ND

N

D

Rha

, Glc

, Gal

, Glc

NA

c, (G

alN

Ac)

N

D

ND

N

D

Hos

t A

nim

als

Ani

mal

s M

an, a

nim

als

Ani

mal

s A

nim

als

Ani

mal

s, m

an

Ani

mal

s A

nim

als

Bird

s A

nim

als,

man

D

airy

M

an

Ani

mal

s A

nim

als

Man

So

urce

of d

ataa

b 5,

57

19, 2

2, 4

8, 5

0 19

, 22,

48,

50

49

9, 1

9, 2

2, 2

7 9,

19,

22,

27

21, 4

1 2,

12

11

7, 2

4, 3

4, 3

6, 4

1, 4

5 7,

24,

34,

36,

41,

45

3, 3

0 14

15

36

, 42

668 FAMILY VI. STREPTOCOCCACEAE

TAB

LE 1

31.

(con

tin

ued)

Char

acte

ristic

S. infantis

S. iniae

S. intermedius

S. lutetiensis

S. macacae

S. minor

S. mitis

S. mutans

S. oligofermentans

S. oralis

S. orisratti

S. ovis

S. parasanguinis

S. parauberis

S. pasteurianus

S. peroris

S. phocae

Cel

l siz

e (m

) 0.

61.

0 ~1

.5

0.5

1.0

ND

N

D

1.

0 N

D

0.5

0.75

0.

7 N

D

ND

N

D

0.8

1.0

ND

N

D

0.6

0.8

ND

C

atal

ase

N

D

Ac

id p

rodu

ctio

n fro

m:

N-A

cety

l-glu

cosa

min

e N

D

+ +

ND

+

+ +

+ N

D

+ N

D

+

+ +

ND

+

A

doni

tol

ND

ND

N

D

ND

ND

N

D

ND

N

D

ND

N

D

ND

Am

ygda

lin

d N

D

+ d

d

+ N

D

d d

ND

ND

Ara

bino

se

Arb

utin

+ +

ND

N

D

d

+

+

ND

d

+ N

D

N

D

A

rabi

tol

ND

ND

N

D

ND

ND

ND

ND

Cel

lobi

ose

ND

+

d N

D

+ +

d +

+ N

D

d d

ND

N

D

ND

Cyc

lode

xtrin

ND

N

D

ND

N

D

N

D

d N

D

ND

N

D

D

extra

n N

D

+ N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

N

D

ND

N

D

D

ulci

tol

ND

ND

N

D

ND

ND

N

D

ND

N

D

ND

d

ND

N

D

ND

Eryt

hrito

l N

D

N

D

ND

N

D

N

D

N

D

d N

D

ND

N

D

N

D

ND

N

D

Es

culin

N

D

ND

N

D

ND

N

D

ND

+ N

D

N

D

ND

N

D

ND

N

D

ND

N

D

Fr

ucto

se

ND

+

ND

N

D

+ +

+ N

D

ND

+

+ N

D

+ +

ND

N

D

+

Fuco

se

ND

ND

N

D

ND

ND

N

D

ND

N

D

ND

N

D

ND

ND

N

D

Gal

acto

se

ND

+f

N

D

ND

+

+ +

+ N

D

+ +

ND

+

+ N

D

ND

G

entio

bios

e N

D

+ N

D

ND

N

D

+ N

D

ND

N

D

ND

N

D

ND

N

D

d N

D

ND

G

luco

nate

N

D

N

D

ND

N

D

N

D

ND

N

D

ND

N

D

ND

N

D

N

D

ND

N

D

2-

Ket

oglu

cona

te

ND

ND

N

D

ND

ND

N

D

ND

N

D

ND

N

D

ND

ND

N

D

ND

5-K

etog

luco

nate

N

D

N

D

ND

N

D

N

D

ND

N

D

ND

N

D

ND

N

D

N

D

ND

G

luco

se

ND

+

+ N

D

+ +

+ +

+ +

+ +

+ +

ND

N

D

+

Gly

cero

l N

D

ND

N

D

d N

D

ND

N

D

ND

G

lyco

gen

+

+

ND

+ +

d

Inos

itol

ND

ND

N

D

ND

ND

N

D

ND

N

D

ND

ND

N

D

Inul

in

d

N

D

d

+

+ N

D

d

Lact

ose

+

+ +

ND

+

+ +

d +

+ +

+ +

+ +

Lyxo

se

ND

ND

N

D

ND

ND

N

D

ND

N

D

ND

N

D

ND

ND

N

D

ND

Mal

tose

+

+ +

+ +

+ +

+ +

+ +

+ +

+ +

+ +

M

anno

se

ND

+

ND

N

D

ND

+

+ +

+ +

ND

N

D

ND

+

ND

N

D

+

Man

nito

l

+

+

+i

+

+

dh

(+)

Mel

ibio

se

d d

d

+

d

+

ND

Mel

ezito

se

+

ND

d

Met

hyl-D

-man

nosi

de

ND

+

ND

N

D

ND

ND

ND

N

D

ND

N

D

ND

ND

N

D

ND

Met

hyl-D

-glu

cosi

de

d +

ND

ND

ND

ND

+

ND

-Met

hylx

ylos

ide

ND

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

Met

hyl-D

-xyl

osid

e N

D

N

D

ND

N

D

N

D

N

D

ND

N

D

ND

N

D

N

D

ND

N

D

Pu

llula

n d

ND

+

N

D

ND

d

N

D

+ N

D

N

D

ND

N

D

R

affin

ose

+

+ d

d +

d d

+ +

d d

+

Rha

mno

se

ND

ND

N

D

ND

ND

N

D

ND

N

D

ND

ND

N

D

ND

Rib

ose

+

d

d

ND

ND

d

+

Salic

in

ND

+

d N

D

ND

+

d +

d

+ N

D

d +

ND

N

D

Sorb

itol

+j

d

h (d)

+

+

dh (

) dh

(+)

Sorb

ose

ND

ND

N

D

ND

N

D

ND

N

D

ND

ND

N

D

ND

Star

ch

ND

+

ND

d

k

d

d +

ND

d

d

ND

d

Su

cros

e +

+ +

+ +

+ +

+ +

+ +

+ +

+ +

+

Ta

gato

se

+

ND

d

d

ND

d

ND

d

ND

d

d

ND

Treh

alos

e

+ +

+

+ d

+ d

d +

+ d

+ +

D

-Tur

anos

e N

D

N

D

ND

N

D

N

D

ND

N

D

ND

N

D

ND

N

D

N

D

ND

X

ylos

e N

D

N

D

ND

N

D

ND

N

D

ND

N

D

ND

X

ylito

l N

D

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

N

D

ND

N

D

Hyd

roly

sis o

f:

Arg

inin

e

+h (

) +

+ dh

()

d +

+h (d

)

Es

culin

+ +

+ +

+

+

dl

+ +

d +

+

Gel

atin

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

GENUS I. STREPTOCOCCUS 669

(con

tin

ued)

Hip

pura

te

ND

+

ND

ND

dh

(+)

Star

ch

ND

+

ND

d

+ N

D

d +

ND

+

+ N

D

ND

N

D

N

D

Pr

oduc

tion

of:o

Aci

d ph

osph

atas

e N

D

ND

N

D

ND

N

D

ND

d

d N

D

+ N

D

d N

D

ND

N

D

ND

N

D

A

lkal

ine

phos

phat

ase

+

+

ND

d

d

d +

+ +

d

+

-L-A

rabi

nosi

dase

N

D

ND

N

D

ND

N

D

ND

N

D

N

D

ND

N

D

ND

N

D

ND

N

D

-D

-Gal

acto

sida

se

+

ND

dk

d

+ d

d

d +

d +

N

D

-D

-Gal

acto

sida

se

+

+

ND

d

+

+

+

p N

D

Ph

osph

o--g

alac

tosi

dase

N

D

ND

N

D

ND

N

D

ND

d

ND

N

D

d N

D

ND

N

D

ND

N

D

ND

N

D

-D

-Glu

cosi

dase

N

D

ND

+

ND

N

D

+ +

+ N

D

+ N

D

+ +

ND

N

D

ND

N

D

-D

-Glu

cosi

dase

ND

d

+ N

D

ND

+ N

D

N

D

+ d

ND

+

N

D

-L

-Fuc

osid

ase

ND

N

D

N

D

ND

N

D

ND

ND

d N

D

ND

N

D

ND

-D-F

ucos

idas

e d

ND

+

ND

N

D

ND

d

N

D

N

D

ND

d

ND

N

D

N

D

-L

-Fuc

osid

ase

ND

N

D

ND

N

D

ND

N

D

ND

ND

N

D

ND

N

D

ND

N

D

ND

-D-G

lucu

roni

dase

ND

N

D

+

-G

luco

sam

inid

ase

ND

N

D

ND

N

D

ND

N

D

d

ND

+

ND

N

D

ND

N

D

ND

N

D

ND

N-A

cety

l--D

-gal

acto

sam

inid

ase

ND

N

D

+ N

D

ND

N

D

ND

+

ND

N

D

ND

N

D

ND

N

D

ND

N-A

cety

l--D

-glu

cosa

min

idas

e N

D

ND

N

D

ND

N

D

ND

N

D

N

D

ND

N

D

ND

N

D

ND

N

D

N-

Ace

tyl-

-D-g

luco

sam

inid

ase

d N

D

+

ND

N

D

+

ND

+

ND

+ N

D

ND

-Mal

tosi

dase

N

D

ND

N

D

ND

N

D

ND

d

d N

D

+ N

D

ND

N

D

ND

N

D

ND

N

D

-M

alto

sida

se

ND

N

D

ND

N

D

ND

N

D

d

ND

ND

N

D

ND

N

D

ND

N

D

ND

Gly

cyl-t

rypt

opha

n ar

ylam

idas

e

ND

N

D

N

D

ND

d

N

D

+ N

D

d N

D

ND

N

D

-D

-Lac

tosi

dase

N

D

ND

N

D

ND

N

D

ND

d

+ N

D

N

D

ND

N

D

ND

N

D

ND

N

D

Le

ucin

e ar

ylam

idas

e N

D

+ +

ND

N

D

+ N

D

+ N

D

+ +

+ +

+ +

ND

N

D

Le

ucin

e am

inop

eptid

ase

ND

N

D

ND

+

ND

N

D

+ N

D

ND

+

ND

N

D

ND

+

ND

N

D

ND

Lysi

ne d

ecar

boxy

lase

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

-D

-Man

nosi

dase

N

D

ND

N

D

ND

N

D

ND

N

D

N

D

N

D

ND

N

D

ND

N

D

-M

anno

sida

se

N

D

ND

ND

N

D

ND

ND

ND

N

D

+

ND

Orn

ithin

e de

carb

oxyl

ase

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

Phos

phoa

mid

ase

ND

N

D

ND

N

D

ND

N

D

d +

ND

d

ND

+k

N

D

ND

N

D

ND

N

D

Py

rogl

utam

ic a

cid

aryl

amid

ase

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

N

D

ND

N

D

ND

N

D

Py

rolid

onyl

aryl

amid

ase

d +

ND

d N

D

N

D

+

Sial

idas

e (n

eura

min

idas

e)

ND

N

D

+ N

D

ND

N

D

d

ND

+

ND

N

D

N

D

ND

N

D

ND

Ala

-phe

-pro

ary

lam

idas

et +

ND

N

D

+ N

D

ND

N

D

ND

N

D

+ N

D

+ N

D

ND

+

+ N

D

-X

ylos

idas

e N

D

ND

N

D

ND

N

D

ND

N

D

N

D

ND

N

D

ND

N

D

ND

N

D

-D

-Xyl

osid

ase

ND

N

D

ND

N

D

ND

N

D

ND

ND

N

D

ND

N

D

ND

N

D

ND

Chy

mot

ryps

in

ND

N

D

ND

N

D

ND

N

D

+ +

ND

+

ND

ND

N

D

ND

N

D

ND

Hya

luro

nida

se

ND

N

D

+ N

D

ND

N

D

ND

ND

N

D

N

D

ND

N

D

Ure

ase

N

D

N

D

ND

N

D

ND

Val

ine

amin

opep

tidas

e N

D

ND

N

D

ND

N

D

+ +

+ N

D

+ N

D

ND

N

D

ND

N

D

ND

N

D

A

ceto

in (V

P)

+ +

+ N

D

+

+h

(d)

+

H2O

2

ND

N

D

N

D

N

D

+ d

ND

+

ND

N

D

+ N

D

ND

N

D

ND

IgA

1 pr

otea

se

ND

N

D

ND

N

D

ND

N

D

d

ND

+

ND

N

D

ND

N

D

ND

N

D

ND

Extra

cellu

lar p

olys

acch

arid

e N

D

ND

+

ND

+ N

D

d

ND

ND

ND

N

D

Am

ylas

e bi

ndin

g N

D

ND

ND

N

D

ND

N

D

N

D

ND

d

ND

N

D

ND

N

D

CA

MP

reac

tion

ND

+

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

ND

N

D

G

rowt

h at

:

10

C

ND

+

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

45C

N

D

N

D

ND

ND

N

D

d

ND

+

ND

d

ND

N

D

ND

Gro

wth

in p

rese

nce

of:

6.5%

w/w

NaC

l N

D

d N

D

ND

d N

D

ND

h (

+)

N

D

40%

bile

N

D

N

D

ND

+

ND

N

D

ND

N

D

ND

+

ND

d

ND

N

D

ND

pH

9.6

N

D

ND

N

D

ND

ND

N

D

ND

ND

+

ND

N

D

N

D

ND

N

D

Hem

olyt

ic R

eact

ion

NH

,,

NH

, ()

, N

H

La

ncef

ield

gro

up a

ntig

en

ND

N

G

NG

, F, C

N

G, D

N

G

NG

N

G, O

w, K

N

G

ND

N

G

A

ND

N

G (F

, G, C

, B)

NG

D

N

D

NG

, F, C

Pe

ptid

ogly

can

type

x N

D

Lys

Ala

13

Lys

Ala

13

ND

N

D

ND

Ly

s-di

rect

Ly

sA

la2

3 N

D

Lys-

dire

ct

ND

N

D

ND

N

D

ND

N

D

ND

M

ajor

cel

l-wal

l car

bohy

drat

e co

nstit

uent

sz

ND

R

ha, G

lc, G

al, G

lcN

Ac

Rha

, Glc

N

D

Rha

, Glc

N

D

Gal

, Glu

, Rtl

Rha

, Glc

N

D

Glc

, Gal

,Glc

NA

c, G

alN

Ac,

(Rha

), R

tly

ND

N

D

ND

N

D

ND

N

D

ND

H

ost

Man

Fi

sh, m

an

Man

M

an

Ani

mal

s A

nim

als

Man

M

an

Man

M

an

Ani

mal

s A

nim

als

Man

A

nim

als

Man

M

an

Ani

mal

s (se

als)

So

urce

of d

ataa

b 28

17

, 18,

35

1, 2

7, 4

0, 5

1, 5

2, 5

5 36

, 42

4 46

3,

30

6, 1

2, 2

7, 3

0 44

3,

30,

32

61

10

53

9, 6

0 35

, 42

29

9, 4

3

670 FAMILY VI. STREPTOCOCCACEAE

TAB

LE 1

31.

(con

tin

ued)

Char

acte

ristic

S. pluranimalium

S. pneumoniae

S. porcinus

S. ratti

S. salivarius

S. sanguinis

S. sinensis

S. sobrinus

S. suis

S. thermophilus

S. thoraltensis

S. uberis

S. urinalis

S. vestibularis

Cel

l siz

e (m

) N

D

0.5

1.25

N

D

0.5

0.8

1.0

ND

0.

820

.98

0.5

GENUS I. STREPTOCOCCUS 671

(con

tin

ued)

Hip

pura

te

+h (

)

h (

d)

d

+

Star

ch

ND

+ d

ND

N

D

+ d

ND

N

D

+

Prod

uctio

n of

:o

Aci

d ph

osph

atas

e N

D

ND

N

D

ND

+

d N

D

ND

N

D

ND

+

ND

Alk

alin

e ph

osph

atas

e d

+

ND

+

dk

d

+

-L

-Ara

bino

sida

se

ND

N

D

ND

N

D

ND

ND

N

D

ND

N

D

ND

N

D

-D

-Gal

acto

sida

se

d +

N

D

d

+

d

-D

-Gal

acto

sida

se

d +

N

D

d d

d +

p

+

Phos

pho-

-gal

acto

sida

se

ND

N

D

ND

N

D

d

ND

N

D

ND

N

D

ND

N

D

ND

N

D

-D

-Glu

cosi

dase

+

+ N

D

ND

+

N

D

+ N

D

N

D

ND

+

d

-D-G

luco

sida

se

dd

d N

D

ND

+

d +

N

D

+

ND

+

-L-F

ucos

idas

e N

D

d N

D

ND

N

D

N

D

N

D

ND

-D-F

ucos

idas

e N

D

d N

D

ND

d

d N

D

N

D

ND

N

D

ND

N

D

-L-F

ucos

idas

e N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

-D-G

lucu

roni

dase

dd

d N

D

+

+ +

-G

luco

sam

inid

ase

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

N-

Ace

tyl-

-D-g

alac

tosa

min

idas

e N

D

+ N

D

ND

N

D

N

D

N

D

ND

N

D

N-A

cety

l--D

-glu

cosa

min

idas

e N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N-A

cety

l--D

-glu

cosa

min

idas

e d

d N

D

ND

d

+

N

D

-Mal

tosi

dase

ND

N

D

ND

+

+ N

D

ND

N

D

ND

N

D

ND

N

D

ND

-Mal

tosi

dase

N

D

ND

N

D

ND

d

N

D

ND

N

D

ND

N

D

ND

N

D

ND

Gly

cyl-t

rypt

opha

n ar

ylam

idas

e N

D

+

ND

d N

D

d

ND

d

-D-L

acto

sida

se

ND

N

D

ND

N

D

d d

ND

N

D

ND

N

D

ND

N

D

ND

N

D

Le

ucin

e ar

ylam

idas

e +

d +

ND

+

ND

+

ND

+

+ +

+ +

ND

Leuc

ine

amin

opep

tidas

e +

ND

N

D

ND

+

+ N

D

ND

N

D

ND

+

+ +

ND

Lysi

ne d

ecar

boxy

lase

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

-D-M

anno

sida

se

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

N

D

-M

anno

sida

se

N

D

N

D

d N

D

O

rnith

ine

deca

rbox

ylas

e N

D

ND

N

D

ND

N

D

ND

+

ND

N

D

ND

N

D

ND

Phos

phoa

mid

ase

ND

N

D

ND

N

D

+ d

ND

N

D

ND

N

D

ND

N

D

ND

N

D

Py

rogl

utam

ic a

cid

aryl

amid

ase

d N

D

N

D

N

D

ND

N

D

d N

D

ND

d

+

Py

rolid

onyl

aryl

amid

ase

dh (

) dh

()

h (

+)

ND

+ +

Sial

idas

e (n

eura

min

idas

e)

ND

+

ND

N

D

ND

ND

N

D

ND

N

D

ND

A

la-p

he-p

ro a

ryla

mid

aset

+ N

D

+ N

D

+ +

N

D

+ N

D

+ +

+

-X

ylos

idas

e N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

-D-X

ylos

idas

e N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

ND

Chy

mot

ryps

in

ND

N

D

ND

N

D

+ d

ND

N

D

ND

N

D

ND

N

D

N

D

H

yalu

roni

dase

N

D

+ N

D

ND

N

D

d

ND

N

D

ND

N

D

Ure

ase

ND

d

N

D

+

V

alin

e am

inop

eptid

ase

d N

D

ND

N

D

+ d

ND

N

D

ND

ND

N

D

N

D

A

ceto

in (V

P)

dh (+

) +

dh (+

)

+ +

+

+ +h

(d)

+ +h

(d)

H

2O2

ND

+

ND

+

ND

+

ND

N

D

ND

N

D

ND

+

Ig

A1

prot

ease

N

D

+ N

D

ND

+ N

D

ND

N

D

ND

N

D

ND

N

D

ND

Extra

cellu

lar p

olys

acch

arid

e N

D

N

D

+ +

+ N

D

+

ND

N

D

ND

A

myl

ase

bind

ing

ND

N

D

ND

N

D

d

ND

ND

N

D

ND

N

D

ND

CA

MP

reac

tion

ND

N

D

+ N

D

ND

N

D

ND

N

D

ND

N

D

ND

N

D

Gro

wth

at:

10

C

ND

ND

ND

45

C

ND

d

d d

ND

d

+

ND

Gro

wth

in p

rese

nce

of:

6.

5% w

/w N

aCl

dd,h (+

)

ND

d

+

h (+)

+

40%

bile

N

D

N

D

d d

d +

d d

N

D

d N

D

pH 9

.6

ND

ND

ND

N

D

N

D

N

D

ND

H

emol

ytic

Rea

ctio

n

NH

N

H,,

()

NH

, (

)v

,NH

N

H

La

ncef

ield

gro

up a

ntig

en

ND

N

G

E, P

, U, V

N

G

NG

, K

NG

, H

NG

N

G

R, S

, T, N

G

NG

N

G

NG

N

G

NG

Pe

ptid

ogly

can

type

x N

D

Lys

Ala

2 (Se

r)

Lys

Ala

24

Lys

Ala

23

Lys

Ala

24,

Lys

Thr

Gly

Ly

sA

la1

3 N

D

Lys

Thr

Ala

Ly

s-di

rect

(Lys

Ala

12)

Lys

Ala

23

ND

Ly

sA

la1

3 N

D

ND

M

ajor

cel

l-wal

l car

bohy

drat

e co

nstit

uent

sz

ND

G

lc, (

Gal

), G

alN

Ac,

Rtl

ND

R

ha, G

al, G

ro

Rha

, Glc

, Gal

, Gal

NA

c R

ha, G

lc, G

lcN

Ac

ND

R

ha, G

lc, G

al

Rha

, Glc

, (G

al),

(Gal

NA

c)

ND

N

D

Rha

, Glc

, Glc

NA

c N

D

ND

H

ost

Ani

mal

s M

an

Ani

mal

s M

an, a

nim

als

Man

M

an

Man

M

an, a

nim

als

Ani

mal

s, m

an

(Dai

ry p

rodu

cts)

A

nim

als

Ani

mal

s M

an

Man

So

urce

of d

ataa

b 16

19

, 27,

40

8, 9

12

, 33

3, 1

9, 3

0, 4

0 3,

19,

26,

27,

30,

40

60

6, 1

2, 3

3 19

, 31

20, 3

9, 5

5 15

8,

9, 1

9, 2

6, 5

9 9

56

672 FAMILY VI. STREPTOCOCCACEAE

a Sym

bols

: +, >

85%

pos

itive

; d, d

iffer

ent s

train

s giv

e di

ffer

ent r

eact

ions

(16

84%

pos

itive

); ,

015

% p

ositi

ve; w

, wea

k re

actio

n; N

D, n

ot d

eter

min

ed.

b Aci

d pr

oduc

tion

from

car

bohy

drat

es o

ften

wea

k an

d di

ffic

ult t

o in

terp

ret.

c Isol

ates

bec

ome

cata

lase

-neg

ativ

e on

subc

ultu

ring.

d S

train

s fro

m b

ovin

e ge

nita

l tra

ct d

iffer

from

thos

e fr

om o

ther

sour

ces.

e Rea

ctio

n va

ries a

ccor

ding

to te

st k

it us

ed.

f Rep

orts

var

y.

g Som

e st

rain

s giv

e w

eak

reac

tions

. h C

hara

cter

istic

scor

e di

ffer

s fro

m F

ackl

am (2

002)

, with

the

latte

rs s

core

giv

en in

par

enth

eses

. i A

cid

prod

uctio

n de

laye

d.

j Aci

d pr

oduc

tion

slow

. k W

eak

reac

tion.

l S

ome

repo

rts n

egat

ive.

mSl

ow re

actio

n.

n Pos

itive

or w

eak

reac

tion

on M

lle

rH

into

n ag

ar.

o Pre

form

ed e

nzym

e ac

tiviti

es d

etec

ted

are

depe

nden

t on

the

test

form

at (s

ubst

rate

) use

d an

d m

ay b

e af

fect

ed b

y cu

lture

con

ditio

ns. I

ndiv

idua

l enz

yme

activ

ities

repo

rted

in th

e lit

erat

ure

may

ther

efor

e va

ry.

p Sub

stra

te-d

epen

dent

. q R

esul

ts m

ay v

ary.

r R

eact

ions

freq

uent

ly w

eak.

s C

onfli

ctin

g re

sults

repo

rted.

t A

la-p

he-p

ro, a

lany

l-phe

nyla

lany

l-pro

line

[ary

lam

idas

e].

u Rep

orte

d re

sults

diff

er.

v -H

emol

ysis

may

be

obta

ined

on

hors

e bl

ood-

cont

aini

ng a

gar.

wO

ant

igen

pre

sent

in b

iova

r 1 st

rain

s. x A

bbre

viat

ion

of p

eptid

ogly

can

type

acc

ordi

ng to

Sch

leife

r and

Kan

dler

(197

2).

y Rib

itol t

eich

oic

acid

and

pho

spho

chol

ine

pres

ent.

z Gal

(gal

acto

se);

Glu

(glu

cose

); G

alN

Ac

(N-a

cety

lgal

acto

sam

ine)

; Glc

NA

c (N

-ace

tylg

luco

sam

ine;

Gro

(gly

cero

l); R

ha (r

ham

nose

); R

tl (r

ibito

l).

aaO

ccas

iona

lly m

an.

abD

ata

obta

ined

from

: 1. A

hmet

et a

l. (1

995)

; 2. B

aele

et a

l. (2

003)

; 3. B

eigh

ton

et a

l. (1

991)

; 4. B

eigh

ton

et a

l. (1

984)

; 5. B

eigh

ton

et a

l. (1

981)

; 6. B

eigh

ton

et a

l. (1

991)

; 7. B

rook

er e

t al.

(199

4); 8

. Col

lins e

t al.

(198

4a);

9. C

ollin

s et a

l. (2

000)

; 10

. Col

lins e

t al.

(200

1); 1

1. C

ollin

s et a

l. (2

002)

; 12.

Coy

kend

all (

1977

); 13

. Dev

riese

e a

l. (1

986)

; 14.

Dev

riese

et a

l. (1

988)

; 15.

Dev

riese

et a

l. (1

997)

; 16.

Dev

riese

et a

l. (1

999)

; 17.

Eld

ar e

t al.

(199

4); 1

8. E

ldar

et a

l. (1

995)

; 19.

Fac

klam

(2

002)

; 20.

Far

row

and

Col

lins (

1984

b, 1

984a

); 21

. Far

row

et a

l. (1

984)

; 22.

Flin

t et a

l. (1

999)

; 23.

Han

dley

et a

l. (1

991)

; 24.

Har

die

(198

6a, 1

986b

); 25

. Har

die

and

Whi

ley

(199

5); 2

6. K

awam

ura

et a

l. (1

998)

; 27.

Kaw

amur

a et

al.

(199

8); 2

8.

Kili

an e

t al.

(198

9b);

29. K

ilppe

r-B

lz

and

Schl

eife

r (19

87);

30. K

ilppe

r-B

lz

et a

l. (1

985)

; 31.

Kra

l and

Dan

eo-M

oore

(198

1); 3

2. O

saw

a et

al.

(199

5); 3

3. P

ier a

nd M

adin

(197

6); 3

4. P

oyar

t et a

l. (2

002)

; 35.

Rob

inso

n et

al.

(198

8); 3

6.

Rur

angi

rwa

et a

l. (2

000)

; 37.

Sch

leife

r et a

l. (1

991)

; 38.

Sch

leife

r and

Kilp

per-

Bl

z (1

987)

; 39.

Sch

lege

l et a

l. (2

003)

; 40.

Sch

lege

l et a

l. (2

000)

; 41.

Ska

ar e

t al.

(199

4); 4

2. T

ong

et a

l. (2

003)

; 43.

Tsa

kalid

ou e

t al.

(199

8); 4

4. V

anca

nney

et a

l. (2

004)

; 45.

Van

dam

me

et a

l. (1

999)

; 46.

Van

dam

me

et a

l. (1

996)

; 47.

Vel

a et

al.

(200

2); 4

8. V

ieira

et a

l. (1

998)

; 49.

Whi

ley

and

Bei

ghto

n (1

991)

; 50.

Whi

ley

and

Bei

ghto

n (1

998)

; 51.

Whi

ley

et a

l. (1

990a

, 199

0b);

52. W

hile

y et

al.

(199

9); 5

3.

Whi

ley

and

Har

die

(198

8); 5

4. W

hile

y et

al.

(198

8); 5

5. W

illco

x et

al.

(200

1); 5

6. W

illia

ms a

nd C

ollin

s (19

90a)

; 57.

Woo

et a

l. (2

002)

; 58.

Zhu

et a

l. (2

000)

; 59.

Col

lins e

t al.

(200

4).

TAB

LE 1

31.

(con

tin

ued)

GENUS I. STREPTOCOCCUS 673

TAB

LE 1

32.

Bio

chem

ical

test

s di

ffer

enti

atin

g -h

emol

ytic

str

epto

cocc

al s

peci

es (

Pyog

enic

gro

up p

lus

An

gin

osus

gro

up)a

Ch

arac

teri

stic

S. pyogenes

S. agalactiae

S. canis

S. didelphis

S. dysgalactiae

subsp. dysgalactiae

S. dysgalactiae

subsp. equisimilis

S. equi subsp. equi

S. equi subsp.

zooepidemicus

S. iniae

S. phocae

S. porcinus

S. anginosus

S. constellatus

subsp. constellatus

S. constellatus

subsp. pharyngis

S. intermedius

Cat

alas

e

+b

Aci

d pr

oduc

tion

from

:

Gly

coge

nd

c

d+

++

d

ND

Man

nit

ol

d

+

d

dd (

)

R

affi

nos

e

d

d

R

ibos

e

++

++

+

++

++

ND

Sorb

itol

d

+

+

Sucr

ose

++

+N

D+

++

++

d

+N

DN

D+

Tr

ehal

ose

++

d+

++

d

+

++

d+

+H

ydro

lysi

s of

:

Arg

inin

e+

++

dd (

+)+

++

++d

()

+

++

++

E

scul

ind

+

d

dd

d+

dd

(+)

++

++

H

ippu

rate

+

+

dd

()

d,f

St

arch

++

+

ND

Prod

uctio

n of

:e

-D-g

alac

tosi

dase

d

dd

N

D

-D

-gal

acto

sida

se

-+

+

ND

d

+

+

-D-g

lucu

ron

idas

ed

dd

++

++

+N

D

d

Py

rolid

onyl

aryl

amid

ase

+

+

d (

+)

A

ceto

in (

VP

)

+d,f

()

dd (

+)+

++

+C

AM

P re

acti

on

+d

(+)

+

+

Lan

cefi

eld

grou

p an

tige

nA

BG

NG

CC

, G, L

, AC

CN

GN

G, F

, CE

, P, U

, VN

G, F

, C, G

, AN

G, F

, C, G

, AC

NG

, F, C

Hos

tM

anM

an,

anim

als

An

imal

s,

man

An

imal

sA

nim

als

Man

, an

imal

sA

nim

als

An

imal

s,

Man

Fish

, an

imal

s,A

nim

als

An

imal

sM

anM

anM

anM

an

a Sym

bols

: +, >

85%

pos

itiv

e; d

, dif

fere

nt s

trai

ns

give

dif

fere

nt r

eact

ion

s (1

684

% p

osit

ive)

; , 0

15%

pos

itiv

e; w

, wea

k re

acti

on; N

D, n

ot d

eter

min

ed.

b Iso

late

s be

com

e ca

tala

se-n

egat

ive

on s

ubcu

ltur

ing.

man

c Som

e st

rain

s gi

ve w

eak

reac

tion

s.d C

har

acte

r sc

ore

diff

ers

from

Fac

klam

(20

02)

wit

h th

e la

tter

s s

core

als

o fo

llow

ing

in p

aren

thes

es. A

n a

ddit

ion

al, u

sefu

l tes

t acc

ordi

ng

to F

ackl

am (

2002

) is

sen

siti

vity

to b

acit

raci

n fo

r S.

pyo

gene

s an

d S.

pho

cae

only

e Pre

form

ed e

nzy

me

acti

viti

es d

etec

ted

are

depe

nde

nt o

n th

e te

st fo

rmat

(su

bstr

ate)

use

d an

d m

ay b

e af

fect

ed b

y cu

ltur

e co

ndi

tion

s. I

ndi

vidu

al e

nzy

me

acti

viti

es r

epor

ted

in th

e lit

erat

ure

may

ther

efor

e va

ry.

f Rep

orte

d re

sult

s di

ffer

.

674 FAMILY VI. STREPTOCOCCACEAE

TABLE 133. Characteristics of Streptococcus species: oral streptococcal species groupsa,b

Anginosus group Mutans group

Characteristic S. a

ngin

osus

S. c

onst

ella

tus

subs

p. c

onst

ella

tus

S. c

onst

ella

tus

subs

p. p

hary

ngis

S. in

term

ediu

s

S. c

rice

ti

S. d

evri

esei

S. d

owne

i

S. fe

rus

S. m

acac

ae

S. m

utan

s

S. o

risr

atti

S. r

atti

S. s

obri

nus

Acid production from: Amygdalin + d + d + + ND + + d + + Arbutin + d + + + + ND d ND + + + Glycogen ND + + Inulin + d + d + + d d Lactose + d + + d + + + ND + + d d Mannitol dc () + + + dc (+) + + + + Melibiose d + + d d + d Raffinose d + + d + + + + Ribose ND ND ND Sorbitol + + c (+) dc (+) +b + + dc (+) Trehalose + d + + d + + + + + + + +Hydrolysis of: Arginine + + + + + Esculin + + + + dc (+) ND + + + + + dc (+) Hippurate + ND ND Production of:e

Acetoin (VP) + + + + + + + + + + + + N-Acetyl--d- glucosaminidase

d + ND ND ND ND ND ND

Alkaline phosphatase

+ + + + ND - d ND ND

Extracellular polysaccharide

+ ND + + + + + +

-d-Galactosidase d + + ND ND ND ND -d-Glucosidase d + + + ND ND ND + ND + ND ND + -d-Glucosidase + + d ND + ND + ND + ND ND -d-Fucosidase + + ND ND ND ND ND ND ND Urease Lancefield group antigen

NG, F,C, G, A

NG, F,C, G, A

C NG, F, C NG ND NG NG NG NG A NG NG

Host Man Man Man Man Animals (man)j

Animals Animals Animals Animals Man Animals Man, animals

Man, animals

aSymbols: +, >85% positive; d, different strains give different reactions (1684% positive); , 015% positive; w, weak reaction; ND, not determined.bAcid production is slow.cCharacter score differs from Facklam (2002), with the latters score given in superscript.dSome reports negative.ePreformed enzyme activities detected are dependent on the test format (substrate) used and may be affected by culture conditions. Individual enzyme activities reported in the literature may therefore vary.fSubstrate-dependent.gSubstrate-dependent.hSubstrate-dependent.iO antigen present in biovar 1 strains.

BERGEYS MANUAL OFSystematicBacteriology IIISecond EditionISBN: 9780387950419PrefaceContents