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2006 Fused phenylcycloalkyl derivatives Q 1040 Synthesis and Evaluation of Novel 8-Oxo-8H-cyclopenta[a]acenaphthylene- -7-carbonitriles as Longwavelength Fluorescent Markers for Hypoxic Cells in Sol- id Tumor. — Compounds (X) are found to be the most effective ones of all markers. — (LIU, Y.; XU*, Y.; QIAN, X.; XIAO, Y.; LIU, J.; SHEN, L.; LI, J.; ZHANG, Y.; Bioorg. Med. Chem. Lett. 16 (2006) 6, 1562-1566; Sch. Chem. Pharm., East China Univ. Chem. Technol., Shanghai 200237, Peop. Rep. China; Eng.) — C. Oppel 20- 090

Synthesis and Evaluation of Novel 8-Oxo-8H-cyclopenta[a]acenaphthylene-7-carbonitriles as Longwavelength Fluorescent Markers for Hypoxic Cells in Solid Tumor

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Page 1: Synthesis and Evaluation of Novel 8-Oxo-8H-cyclopenta[a]acenaphthylene-7-carbonitriles as Longwavelength Fluorescent Markers for Hypoxic Cells in Solid Tumor

2006

200620.fm Page 97 Thursday, April 13, 2006 1:02 PM

Fused phenylcycloalkyl derivativesQ 1040 Synthesis and Evaluation of Novel 8-Oxo-8H-cyclopenta[a]acenaphthylene-

-7-carbonitriles as Longwavelength Fluorescent Markers for Hypoxic Cells in Sol-id Tumor. — Compounds (X) are found to be the most effective ones of all markers. — (LIU, Y.; XU*, Y.; QIAN, X.; XIAO, Y.; LIU, J.; SHEN, L.; LI, J.; ZHANG, Y.; Bioorg. Med. Chem. Lett. 16 (2006) 6, 1562-1566; Sch. Chem. Pharm., East China Univ. Chem. Technol., Shanghai 200237, Peop. Rep. China; Eng.) — C. Oppel

20- 090