SYLLABUS AND REGULATIONS held onsrnmcollege.ac.in/event_img/627559b1d5953b524883aeab0d586836… · SYLLABUS AND REGULATIONS UNDER CHOICE BASED CREDIT SYSTEM (CBCS) ... Mass Spectrometry

SYLLABUS AND REGULATIONS

UNDER

CHOICE BASED CREDIT SYSTEM (CBCS)

(Those who joined in 2018-2019 and after)

M.Phil., Programme in Chemistry

Regulations 2018

SRI S. RAMASAMY NAIDU MEMORIAL COLLEGE

SATTUR- 626 203

(An Autonomous Institution Affiliated to Madurai Kamaraj University, Madurai)

(Re-Accredited with Grade ‘A’ by NAAC)

Placed at the

meeting of

Academic Council

held on

17.04.2018

SRNMC Regulations-2018 Syllabus

1

Objectives

The syllabus for M. Phil (Chemistry) under the semester system has been designed to

provide the students an in depth knowledge on various fields of research in Chemistry and

prepare for various competitive examinations such as CSIR, GATE, NET etc

Eligibility for admission

Candidates who have passed M.Sc (Chemistry) examination conducted by the Madurai

Kamaraj University or any other university duly recognized by the Syndicates of Madurai

Kamaraj University as equivalent there to are eligible to join this course and the college shall

admit M.Phil students through an Entrance Test conducted by Madurai Kamaraj University. The

admissions will be made once in a year. The candidates for M.Phil shall be admitted only in the

regular (Full Time) mode and not in Part-time or distance learning or any other mode.

Duration of the Course

The duration of the course shall be one academic year comprising two semesters.

Subjects of study

The main subjects of study offered for M. Phil (Chemistry) course shall consist of

the following.

Semester I

There shall be three papers

Paper I – Research Methodology

Paper II – Spectroscopic techniques and their applications

Paper III – Elective

i. Co-ordination complexes and their Applications

ii. Advanced Organic Chemistry

Semester II

Dissertation and Viva-voce only


2

Evaluation

The performance of a scholar is evaluated in terms of percentage of marks. Evaluation for

each course shall be done by a continuous internal assessment by the concerned teacher as well

as by an end semester examination of 3 hours duration and will be consolidated at the end of the

course. The ratio of the marks to be allotted to continuous internal assessment and to end

semester examination is 25:75 (Internal 25 and External 75)

Internal Test:

a) Maximum marks for test

(Two tests and their average) : 15 marks

b) Maximum marks for (Seminar Activities /

Quiz / Assignment/Presentation Skills) : 10 marks

Total : 25 marks

Passing Minimum

1. 50% of the aggregate (external+ internal).

2. No separate pass minimum for internal.

3. 34 marks out of 75 is the pass minimum for the External

Dissertation (II semester)

4. 1. 50% of the aggregate (Dissertation evaluation + Viva voce)

5. 2. 25 marks out of 50 marks is the pass minimum for Viva voce

6. 3. No separate pass minimum for the internal Dissertation evaluation

7. 4. 34 marks out of 75 marks is the pass minimum for the external Dissertation evaluation

Question Paper Pattern

Part A 5x7=35 Marks

Five questions (either or type).

One from each unit.

Part B 4x10=40 Marks

Four questions out of seven.

Total 75 Marks


3

M. Phil (Chemistry)

Table – 1: Course Details and Scheme of Examination

(with effect from the academic year 2018 – 2019)

FIRST SEMESTER

Subject Subject

Code

Weekly

Contact

Hours

Credits Exam

/Hours

Marks

Int. Ext Total

Paper I

Research Methodology

MP18CH11 6 5 3 25 75 100

PaperII(core)

Spectroscopic techniques

and their applications

MP18CH12 6 5 3 25 75 100

Paper III Elective

1) Co-ordination

complexes and their

Applications

2) Advanced Organic

Chemistry

MP18CHE11

MP18CHE12

6 5 3 25 75 100

SECOND SEMESTER

Subject Subject

Code Credits

Marks

Int. Ext. Total

Dissertation MP18CHDN 7 75 75 150

Viva Voce MP18CHVV 3 - 50 50

Total 10 200


4

SRI S.RAMASAMY NAIDU MEMORIAL COLLEGE

(An Autonomous Institution Re-accredited with ‗A‘ Grade by NAAC)

SATTUR – 626 203.

Department of Chemistry

(For those who are joining in 2018-2019 and after)

SYLLABUS

Programme : M.Phil (Chemistry) Subject Code : MP18CH11

Semester : I No. of Hours allotted : 6 /Week

Subject : Core - Paper I No. of Credits : 5

Title of the Paper: RESEARCH METHODOLOGY

Objectives:

To know the information about research journals for publication and writing the thesis

To introduce the students to C-language and enable to solve simple programs in C.

To gain knowledge on various purification techniques

Unit I: Literature Search

Searching the chemical literature Primary sources – Journals, periodicals, patents,

abstracts; Secondary sources including list of titles, reviews – Annual Reviews – Treatises,

Serials, monographs and text books, encyclopedia, catalogues, index of tabulated data – Science

citration index – Citation searching in Chemical literature – Location of Journal article -

Materials on a given topic – Information about Literature searching online – Popular websites in

Chemistry

Introduction to Internet and its applications – web browsers – World Wide Web – Search

Engines – e-journals - literature Survey in Chemistry – Popular journals and websites in

Chemistry –Databases in Chemistry - literature searching and collection using e-journals

Unit II: Error in chemical analysis and statistics

Classification of errors – accuracy – precision –minimization of errors- Significant

figures – mean – standard deviation – normal or Gaussian distribution – Reliability of results –

confidence interval – comparison of results – Q test-student‘s t-test, F test, paired t-test Analysis

of Variance (ANOVA)– correlation and regression – the least squares method for deriving

calibration plots like straight line – power curve – exponential curve – second degree parabola –

general methods used, standard addition , universal standard method – problems in these

methods using least square fitting – quality assurance and control charts.


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Unit III: Methods of separation

General methods of Isolation and purification of Chemicals – Solvent Extraction –

Fractional crystallization – Sublimation – Distillation – Vacuum distillation – Purification of

solvents Chromatography Techniques: - Paper, Column, Ion-exchange, GC and HPLC

techniques and applications

Unit IV-Advanced Instrumentation Techniques

Principle, Instrumentation and applications of the following techniques – Electron

microscope-Scanning Electron Microscope (SEM)- Modern Transmission electron microscope

(TEM)-Scanning probe microscope (SPM)-Atomic force microscope (AFM)-Scanning

Tunneling Microscope (STM)-Thermo gravimetric analysis-Derivative Thermo gravimetric

DTG-Differential scanning calorimetry(DSC)-Enthalpimetric methods.

Unit V-Computers in Chemistry

Application of ‗C‘ language in Chemistry – Introduction of ‗C‘ languages – Character set

in C- C Keywords and Identifiers – Constants, variables, Data types and operators –

Computation of some simple problems in Chemistry such as 1) Half-life period, 2) Normality,

Molarity and Molality of a solution 3) Determination of solubilities of sparingly soluble salts 4)

Ionic strength of an electrolyte 5) computation of 13

C chemical shift in organic compounds.

Reference Books

1. J. March, ―Advanced Organic Chemistry‖, Fourth Edition, John Wiley & Sons, New

Delhi, 2000.

2. J.Mendham, RC Denney, JD Barnes, M.Thomas B.Sivasankar Text Book of Vogel‘s

Quantitative chemical Analysis Sixth Edition Pearson,2013

3. Mick Wilson ,G.Smith,M.Simmons and B.Raguse,Nano technology Basic science and

emerging Tecnologies

4. Er.Rakesh Rathi Nano Technology Revolution of 21st century,S Chand and company

PVT LTd 2013.

5. U.N Dash ,Analytical Chemistry Theory and Practice ,Sultan Chand & Sons Educational

Publishers ,New Delhi Third Edition 2013.

6. Skoog, Holler, Nieman, Thomson, Principles of Instrumental Analysis, Asia Pvt. Ltd.,

Singapore, 2004.

7. K.V. Raman, Computers in Chemistry, Tata McGraw – Hill Publishing Co.Ltd., New

Delhi,1993.

8. 6. E.Balagurusamy, Programming in ANSI-C , 2ndedition, Tata McGraw – Hill

Publishing Co.Ltd., New Delhi,1998.

Prepared by : Dr. T. Kavitha

Signature :


6

SRI S.RAMASAMY NAIDU MEMORIAL COLLEGE


SATTUR – 626 203.



SYLLABUS

Programme : M.Phil (Chemistry) Subject Code : MP18CH12


Subject : Core - Paper II No. of Credits : 5

Title of the Paper: Spectroscopic techniques and their Applications

Objectives:

Acquire knowledge about atomic and molecular spectroscopic Techniques

To gain knowledge on Inorganic photo chemistry

Know the principle and applications of 1H and

13 C NMR

Unit 1 - Atomic spectroscopy

Optical atomic spectroscopy - Designs of Optical Instruments - Types of Optical

Instruments - Principles of Fourier Transform Optical Measurements-Atomization Methods –

Sample Introduction Methods Atomic adsorption spectrometry, Atomic fluorescence

spectrometry - Sample Atomization Techniques-Atomic Absorption Instrumentation -

Interferences in Atomic Absorption Spectroscopy - Atomic Absorption Analytical Techniques -

Atomic Fluorescence Spectroscopy Atomic X-ray Spectrometry - Principles and Instrument

Components - X-ray Fluorescence Methods - X-ray Absorption Methods - X-ray Diffraction

Methods - The Electron Microprobe - Instrumental Analysis for heavy metals

Unit II - Molecular spectroscopy

Ultraviolet – Visible molecular absorption spectroscopy - Principle and instrumentation -

The Magnitude of Molar Absorptivities - Absorbing Species – Qualitative Applications -

Spectrophotometric Kinetic Methods - Spectrophotometric Studies of Complex Ions

Infra-red Absorption Spectrometry - IR Instrumentation - IR Sources and Transducers -

Mid-IR Absorption Spectrometry - Mid-IR Reflection Spectrometry - Photo acoustic IR

Spectroscopy - Near-IR Spectroscopy - Far-IR Spectroscopy - IR Emission Spectroscopy - IR

Microscopy

Advances in Raman Spectroscopy - Applications of Raman Spectroscopy - Other Types

of Raman Spectroscopy

Molecular Mass Spectrometry - Molecular Mass Spectra - Ion Sources - Mass

Spectrometers - Applications of Molecular Mass Spectrometry - Quantitative Applications of

Mass Spectrometry - Structure determination of organic compounds by UV-VIS, IR, 1H &

13C

NMR and Mass spectroscopic techniques.


7

Unit-III -Physical Methods in Chemistry - I and Inorganic Photochemistry

Electronic spectra of transition metal complexes –evaluation of 10 Dq and β values for

cobalt and nickel octahedral complexes –Applications to simple coordination complexes-charge

transfer spectra-combined uses of IR and Raman spectroscopy in the structural elucidation of

simple molecules like N2O, ClF3, NO3- and metal complexes (carbonyl and Cyanides).

Photophysical and Photochemical processes of coordination complexes (Cobalt (III)

complexes, Chromium (III) complexes and Ruthenium complexes) – Adamson‘s Rule - Solar

energy conversion-photo electrochemical cells-water splitting –semiconductor solar cells.

Unit IV-Physical Methods in Chemistry - II

Multinuclear - NMR Spectroscopy – Applications to Inorganic compounds (1H, 31P,

19F and 11B nuclei to structural problems) - Fluxional NMR and Paramagnetic NMR- Contact

shift and Pseudo contact interactions- Lanthanide shift reagents. Applications of EPR to simple

inorganic radicals – Evaluation of g and A tensors - Zero field splitting and Kramer‘s degeneracy

– ESR spectrum of metal complexes – ESR spin trapping techniques Mossbauer spectroscopy –

Applications to iron and tin complexes.

Unit V- Organic Spectroscopy:

Application of 1H and 13C NMR in structural elucidation of organic compounds –

Analysis of complex NMR spectra – Use of multipulse

techniques in NMR – Application of 2D NMR, HETCOR, COSY, NOESY and INADEQUATE

techniques - Problem solving approach involving all the spectroscopic techniques including UV,

IR, NMR and mass spectroscopy.

Reference Books

1. Skoog, Holler, Nieman, Thomson, Principles of Instrumental Analysis 5th

Edition, Asia

Pvt. Ltd., Singapore, 2003.

2. R.S. Drago, Physical Methods in Inorganic Chemistry 3rd ed., Wiley Eastern

Company,1999.

3. E.A.V. Ebsworth, Sturctural Methods in Inorganic Chemistry 3rd ed., ELBS,1987.

4. Huheey, James E, Inorganic chemistry, IV Ed., Principles of ―‖Structure; and Reactivity

Collins College Publishers,1993.

5. Nakamoto and Dazuo, Infrared and Raman spectra of Inorganic and Coordination

Compounds, IV ed., john Whiley and Sons, NY,1986.

6. Jag mohan, Organic Spectroscopy, Narosa Publishers, 2001.

7. William Kemp. Organic Spectroscopy, Macmilan, 3rd ed., 1991


Signature :


8

SRI S.RAMASAMY NAIDU MEMORIAL COLLEGE (An Autonomous Institution Re-accredited with ‗A‘ Grade by NAAC)

SATTUR – 626 203.

Department of Chemistry (For those who are joining in 2018-2019 and after)

SYLLABUS

Programme : M.Phil (Chemistry) Subject Code : MP18CHE11


Subject : Elective - Paper I No. of Credits : 5

Title of the Paper: Co-ordination complexes and their Applications

Objectives:

To know the applications of UV-Visible, IR spectroscopy and ESR spectroscopy in the

study of coordination compounds

To study applications of organo metallic compounds

To know the applications of metal in medicine

UNIT I - Co-ordination Compounds

Co-ordination chemistry - Methods of preparation of complexes - Isomerism in

complexes - Complexes and their stability - Chelate effect - Stability constants and their

determination – Complexes of Metals in different oxidation states - Applications of complex

formation in analytical chemistry.

UNIT II - Theories in co-ordination chemistry

Term symbols for dn-ions - Energy level diagrams for weak field and strong field – Spin-

orbit coupling - Nephelauxetic effect - Charge transfer spectra - Applications of UV, IR, NMR

and ESR spectroscopy techniques in the study of co-ordination chemistry - Magnetic interactions

– Magnetic susceptibilities determination of co-ordination complexes.

Application of VB, MO, CF and LF theories in co-ordination chemistry - Splitting of d-

orbitals - Spectrochemical series - Jahn Teller distortion.

UNIT III - Organometallic compounds and reaction mechanism

Organometallic compounds - Metallocences - Ferrocene - Arene complexes – Non-

aromatic olefins and acetylenes complexes – Catalysis by organometallic compounds –

Wilkinson‘s catalyst – Oxo process –Wacker process – Ziegler – Natta catalysis.

Inorganic reaction mechanism – Inert and labile complexes – Substitution

reactions in six coordinated and four coordinated complexes – Trans effect –. Mechanism of

electron transfer reactions - Outer sphere mechanism, Inner sphere mechanism, Two electron

transfer reactions.


9

UNIT IV - Bioinorganic chemistry

Bioinorganic chemistry – Energy sources for life Cytochromes- Dioxygen binding

transport and Utilization-Binding of dioxygen to myoglobin-physiology of myoglobin and

hemoglobin-Structure and functions of hemoglobin- Ferredoxins and rubredoxins –Blue copper

proteins—Vitamin B12 and the B12 Coenzymes -Nitrogen fixation – Role of metal ions in

biological systems.

UNIT V-Metals and Chelation in Medicine

Dependence of biological Growth on the concentration of Essential and toxic Elements-

Disease due to metal deficiency and treatment –Thermodynamic and pharmacokinetic properties

of chelating drugs in metal in detoxification—Antimicrobial activities of metal chelates-anti

inflammatory effects of zinc and copper compounds-anticancer activity of platinum complexes-

anticancer activity of other metal complexes-vanadium complexes in the treatment of diabetes

References

1. Purcell and Kotz, Inorganic chemistry, 2013.

2. Cotton & Wilkinson Advanced Inorganic Chemistry, Wiley Eastern Ltd.

3. James E.Huheey, Inorganic Chemistry, 3rd

Ed., Harper Int. 1996.

4. Tuli, Malik & Madan, Selected Topics in Inorganic Chemistry, S.Chand & Co., 2002.

5. Asim K.Das, BioInorganic ChemistryBooks and Allied (P)Ltd Publishers, 2013.

6. Puri, Sharma & Kalia, Principles of Inorganic Chemistry, S.Chand & Co., 1998.


Signature :


10

SRI S.RAMASAMY NAIDU MEMORIAL COLLEGE (An Autonomous Institution Re-accredited with ‗A‘ Grade by NAAC)

SATTUR – 626 203.

Department of Chemistry (For those who are joining in 2018-2019 and after)

SYLLABUS

Programme : M.Phil (Chemistry) Subject Code : MP18CHE12


Subject : Elective - Paper II No. of Credits : 5

Title of the Paper: Advanced Organic Chemistry

Objectives:

Acquire knowledge about stereochemistry of organic compounds

To know the applications of reagents in organic synthesis

To understand the basic concepts of ultrasonic sound used inorganic synthesis

To learn about microwave assisted reactions

UNIT I -STEREOCHEMISTRY

Introduction to molecular symmetry and point groups.Topicity and prostereoisomerism,

nomenclature of stereotopic ligands and faces, stereoheterotopic ligands – centre of chirality,

assignment of absolute stereochemistry, axial chirality, planar chirality and

helicity.Conformational analysis – acylic systems, cyclic systems, cyclohexane and

decalins.Conformation and reactivity with examples.Stereoselectivity – classification,

terminology, principle of stereoselectivity, examples of diastereoselectivity and

enantioselectivity including few examples from pericyclic reactions.

UNIT II -REACTIVE INTERMEDIATES

Reactive intermediates: Generation, structure and reactivity of carbenes, nitrenes and free

radicals – addition and rearrangement reactions – substitution reactions by free radicals. Name

reactions: Favorskil rearrangement, Stork enamine reaction, Mannich reaction and Baeyer

Villiger oxidation, Diels-Alder Reaction, Hofmann's Rule and Hofmann Elimination reaction.

UNIT III -REAGENTS IN ORGANIC SYNTHESIS

Reagents in organic synthesis: Uses of NBS, lithium diisopropylamide, aluminium

isopropoxide,lithium aluminium hydride, potassium tertiary butoxide and trimethylsilyl iodide.

Reagentscontaining P,S, B, Si - protecting groups – hydroxyl, amino, carbonyl and carboxylic

acid.synthetic analysis and planning – control of stereochemistry.


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UNIT IV -Green Chemistry

Introduction about green chemistry-designing a green synthesis-choice of starting

materials-choice of reagent –choice of catalyst-choice of solvent-Green reagent-polymer

supported catalyst –Phase –transfer catalysis in green synthesis-Elimination reactions-C-

alkylations-Darzen‘s reaction-The witting reaction-Alkylation

UNIT V -Microwave Induced Green synthesis

Introduction-Application-Microwave Assistant reactions in water-Hofmann Elimination –

hydrolysis-Hydrolysis of benzyl chloride-hydrolysis of benzamide-oxidation of toluene –

oxidation of alcohols-saponification- orthoester Claisen rearrangement-

Sonochemistry Fundamentals of sound and ultrasound – cavitation and its principle –

instrumentation – homogeneous and heterogeneous processes – sonoluminescence – uses in

chemistry, material science, medicine and life – synthetic applications – esterification,

saponification, hydrolysis, substitution, cannizaro reaction, Strecker‘s synthesis

References

1. J. March, ―Advanced Organic Chemistry‖, Fourth Edition, John Wiley & Sons, New

Delhi, 2000.

2. Stereochemisty of carbon compounds.Ernest L.Eliel.

3. stereochemistry of organic compounds –Principle and applications D.Nasipuri.

4. Stereochemistry –conformation and Mechanism,p.s.Kalsi

5. Green chemistry by V.K.Ahluwalia, M.Kidwai , Anamaya publishers, - Revised edition,

2004

6. Green Chemistry –Environment Friendly Alternatives by Rashmi Sanghi and M M

Srivastava - Narosa Publishing House.-2003


Signature :


12

SRI S. RAMASAMY NAIDU MEMORIAL COLLEGE


SATTUR – 626 203



SYLLABUS

Programme: M. Phil (Chemistry) Subject Code : MP18CHDN

Semester : II

Paper : DISSERTATION No. of credits: 10

DISSERTATION AND VIVA-VOCE

OBJECTIVES:

To develop the ability of the students to prepare a Dissertation

To get clear idea about the new concepts in Chemistry Research fields

Regulations for the Dissertation

The topic of the Dissertation may be based on the Chemistry.

Evaluation method for Dissertation:

Max Marks

Internal External Total

(average)

Dissertation 75 75 150

Viva voce 50 50

Total 200

Viva voce examination should be evaluated by the external examiner.

The report of the Dissertation must be in the prescribed format. It should be typed neatly

in Ms Word. The font size of the letter should be 12 with double space.

The format of the Dissertation should have the following components.

First page should contain:

1. Title of the Dissertation

2. Name of the candidate.

3. Register number.

4. Name of the supervisor.

5. Address of the institution.

6. Month & year of submission.


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Contents:

1. Declaration by candidate

2. Certificate by supervisor

3. Acknowledgement.

4. List of tables

5. List of figures

6. Chapters(not exceeding six)

7. Bibliography

8. Appendix

The number of pages in the Dissertation may be 100 to 150. Three copies of the

Dissertation with hard binding should be submitted.

Prepared by: Dr. T. Kavitha

Signature :

CHAIRMAN DEAN-ACADEMIC

Documents

SYLLABUS AND REGULATIONS held onsrnmcollege.ac.in/event_img/627559b1d5953b524883aeab0d586836… · SYLLABUS AND REGULATIONS UNDER CHOICE BASED CREDIT SYSTEM (CBCS) ... Mass Spectrometry