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    Oral Surgery

    Odontogenic Infections

    Done by : Muad Salahuddin Al-Zoubi

    Dedicated to : Rmz Al-Rabadi

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    This lecture is about infections, what infections are in general and how to deal with infections

    we should know about.

    The subject will be divided into the oral infectionsand more importantly the maxillofacial

    infectionsthat occur when the infection proceeds from any oral or primary space (to be

    mentioned below) to the secondary spaces. When, where and how they will be treated, these

    will be encountered in this and the coming lectures.

    Microbiology of infections

    The oral cavity is considered to be dirtier than the other sites of the human being, this means

    that the bacteria in the oral cavity are very numerous and very diverse and the bacteria which

    are responsible for most of the infections in the oral cavity are oral flora (i.e. present in the

    mouths of every normal individual). In general, the most common bacteria in the oral cavity

    are the streptococci and S.viridansin particular, the types of bacteria present in the oral cavity

    are either aerobic gram positive cocci(e.g. S.viridans), anaerobic gram positive coccior

    anaerobic gram negative rods, so the oral cavity is polymicrobial. In general, the oral

    infections are mixed infections, which means that if a sample is taken from an oral infection

    and tried to be studied microbiologically, not only one type of bacteria will be found but

    several types will be found (i.e. aerobic and anaerobic bacteria, cocci and rods, gram positive

    and negative).

    The aerobic infections (alone) constitute about 5% of oral infections (e.g. S.viridansand other

    sorts of gram positive aerobic bacteria). The anaerobic infections (purely anaerobic) constitute

    about 35% of oral infections (e.g. abscesses are mostly if not totally anaerobic infections). The

    remaining 60% infections (the majority) are mixed infections.

    * The sites involved in infections are the teeth and periodontium, either the apex, root canals

    (and lateral canals) or the periodontium itself.

    In general, infections tend to go through the easiest route (with the least resistance), e.g. thebacteria that caused the infection will try to spread (against the patients immune system),

    they will spread through the routes that are easy to pass through, say, there are two routes,

    one with thick bone and the other with thin less dense bone, the bacteria will spread through

    the least resistant route (thin bone in this case).

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    What determines the location or spread of infection ?

    Example: patient with abscess in the vestibule, or in the floor of the mouth that raised the

    tongue !

    so, what determines the location of the abscess formation ?

    1-Thickness of bone.

    2- Muscle attachment (mentalis, zygomaticus major and minor, buccinators, muscles of the

    lips .etc.).

    Suppose that a patient had irreversible pulpitis, the source of bacteria will be the root canals,

    the bacteria start to increase in number, then the bacteria go out from the root apex, if the

    apex is located below the buccinator muscle attachment (upper tooth) or above mentalisfor

    example, the infection will spread to the inside of the oral cavity, in this case the abscess will

    be in the oral vestibule (vestibular abscess) if we considered the thin bone to be the buccal

    bone. If the root is long (e.g. upper canine) and the apex is located above the buccinator

    muscle attachment, the infection will spread above the muscle attachment, the infection

    might reach the eye and the patient is seen having a closed eye because of swelling, so the

    muscle attachment determines the location of the abscess and also the bone thickness (palata

    bone is thicker in this case)

    Examples :- If the palatal root of the upper first molar is the nonvital root, the palatal root is closer to the

    palatal bone, in this case the abscess will appear palatal (the patient will complain of palatal

    swelling).

    - Infections in certain stages may develop swelling in the submandibular area and the skin

    might become very thin, when the pus accumulates in the abscess the abscess will try to

    expand taking over the normal tissues, if the patient is neglecting, the abscess might reach a

    level that it drains extra-orally (very unlikely to be seen) but it might be seen especially in thedeprived areas where (poor countries with poor no medical care).

    - In general, if maxillary teeth developed abscesses, most likely they will be vestibular,

    exceptions include the palatal root of upper first molar will develop palatal abscess (very close

    to palate), and the lateral incisor (palatal abscess) because the root is inclined palatally, canine

    has long root it may form abscess higher in level the levator anguli oris muscle, it will appear in

    the canine space (not intraorally). Mandibular teeth in most of the cases form vestibular

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    3- If the patient toxic (dehydrated hasnt eaten or drunk anything, very tired, this is a sign of a

    bad infection)

    4- Ask if the patient had any treatment for this infection, if he underwent drainage, took

    antibiotics, underwent RCT, etc.

    5- Vital signs, high grade temperature is an indication of severe infection, heart rate of more

    than 100 beat/minute is also an indication of severe infection (normal HR is 60-100), also

    respiratory rate of more than 16/minute is an indication of severe infection.

    6- If the infection has lead to any obstruction in the airways this is absolutely dangerous, an

    example is an infection that reached the sublingual space resulting in an elevation of the

    tongue that lead to airway obstruction its very dangerous not because it can spread to

    somewhere, but simply because it can kill the patient, its very vital in such a case to think of it

    as an emergency.

    7- Physical examination, is the area of the infection indurated or fluctuant, if the infection is

    still in the area of developing it will feel indurated, if the infection is well established and an

    abscess was formed it will feel fluctuant, if its less indurated this means that the abscess is

    developing but its not wellestablished, and we need to take radiographs to locate the tooth

    that resulted in this.

    Another determinants of the severity of infection and the spread of the infection that shouldbe taken into consideration is the patient immune defense, if the patient is already

    immunocompromised or medically compromised, the infection will spread rapidly, especially

    those with uncontrolled diseases such as DM (if DM patients is well controlled, we deal with

    them as normal people), patients with uncontrolled DM have very deranged immune system

    to the degree that any sort of simple infection has the ability to spread. Uremia in cases of

    chronic renal disease, instead of discharging the waste in the urine, they will stay in the body.

    Alcoholism, those who drinks alcohol in large amounts that exceeds particular limits, for

    females if they consume more than 14 units a week, for males more than 21 units a week,

    those people has deranged immune system, they can easily develop infections since they

    dont have a proper competent immune system.Patient who underwent chemotherapy, they

    definitely are immunocompromised, some cells (including stem cells) are killed,

    immunosupressed patients taking steroids (steroids are anti-inflammatory and

    immunosuppressants) can also easily get infections.

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    Always check the glucose level (DM is very common in our country), if you see a patient who

    developed an abscess, has a carious tooth but the progression was very quick, you should

    think about having a problem in the immune system, the first thing you should think about

    that the patient does not know that he has DM so we check the glucose, so, oral infection

    might be the cause of discovering a chronic disease (e.g. glucose level of 400 mg/dl)

    For patients who are immunocompromised that we think they will develop an infection, wegive antibiotic before we treat (prophylactic antibiotic).

    Treat or Refer?!

    If I am a GP and a patient came to my clinic, shall I treat or shall I refer this patient, what are

    the things that are beyond my expertise so that I refer the patient to the hospital or to

    specialist?

    1- Rapid progression, if a patient told you that two days ago he felt toothache then he came to

    you with swelling, his eye is closed (swelling), the floor of the mouth is raised this is a case of

    rapid progression, but if you see a small abscess its not rapidly progressive.

    2- Difficulty in breathing, (infection of sublingual area, an emergency), here you dont refer the

    patient to a specialist, but you call the specialist by yourself, and tell him that the patient has

    an infection, his tongue is raised and has a difficulty in breathing and we need to send him to

    the hospital because he might need intubation to ensure normal breathing.

    3- Space involvement, there are primary and secondary spaces, primary spaces are those to

    which the infection is firstly spread e.g. vestibular space/vestibular abscess, submandibular

    area directly from the root apex, canine space, and the secondary spaces are those that are

    not firstly affected e.g pharyngeal space.

    Abscessprimary spacesecondary space (more serious secondary infection)

    So if the infection involved several spaces or involved a secondary space we think that this is

    serious, this patient needs referral.

    4- High grade temperature (above 38.1C), the patient is thought to have a serious infection

    and might need referral, you call the specialist, this patient might need to be given fluids,

    antibiotics or hospital admission.

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    5- Trismus, especially in the case of posterior teeth involved in infection, this might affect the

    muscles of mastication, and it might be very severe, imagine that a patient has an infection

    and developed severe trismus, this patient wouldnt be able to eat, the infection will spread

    and might affect breathing and swallowing, those need something to be done and shouldnt

    be left alone, any limitation of mouth opening means that theres trismusbut the severity

    varies if the patient cannot open more than 1 cm (sometimes less than that), this is severe

    trismus, the patient is very toxic

    6- Medically compromised patients, a patient has an abscess and while taking the history its

    found that he had undergone a kidney transplant, he might have rapid progression, space

    involvement or trismus, so those patients should be dealt with very rapidly, we call a specialist

    and admit the patient to the hospital, we should attack the infection aggressively.

    7- Toxic appearance, a patient with small dental abscess, but the patient is very toxic, tired,hasnt eaten, hasnt slept, pale, this patient deserves to be referred to a proper specialist

    Treatment

    - When do we treat surgically?

    - The answer is ALWAYS.

    Its not right to give him antibiotics beforesurgical treatment, to resolve the infection then

    treat the tooth endodontically.

    The surgical treatment includes one of following options :

    - Incision and drainage.

    - Extraction of the tooth.

    - Pulp extirpation and drainage through the root canals

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    Abscess and Cellulitis

    Cellulitis Abscess

    Duration Shorter Longer

    Pain More Less

    Localization Less localized (diffuse) More localizedSurface temperature Higher than abscess Lower than cellulitis

    Loss of function More Less

    Bacterial involvement Aerobic Anaerobic

    Tissue fluids More edematous Pus

    Level of seriousness More Less

    Cellulitis is more dangerous, the infection is in the subcutaneous tissue and spreads rapidly,

    in the case of an abscess, the body has succeeded to localize the infection in a certain area, in

    the case of cellulitis the body couldnt localize the infection and the infection is spreading

    rapidly (more severe).

    Support the patient medically

    Give antibiotics after surgery, they will act more rapidly since the surgery has lessened the

    load of bacteria. Incision and drainage has long been known and had saved the lives of manypeople, surgery on its merit is the most important, and it can heal the patient, but we need to

    support the patient after we treat the infection in the surgical maneuver, we need to make

    sure that the patient is well hydrated so we advice him to take fluids and we give him

    antibiotics to make sure that this patient will recover soon.

    When to give antibiotics?

    Diffuse swelling, immunocompromised patient, space involvement, severe pericoronitis,

    osteomylitis.

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    Empirical therapy

    It is a matter of expecting, if a patient has an abscess, we expect anerobic infection, so, we

    give amoxicillin and metronidazole.

    Or we take a sample and ??????????!!!!!!!!!!!

    BUT I expect that the doctor was going to talk about taking a sample and sending it to culture

    to know exactly the causative micro-organism and prescribe the antibiotic which is known to

    be most effective against this micro-organism(s).

    THANK YOU!

    Continue below, there are appendices!

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    Appendix A

    Since the lecture was not very clear, this appendix includes images from the related chapter

    of the book and boxes that summarizes the most important points in a trial to compensate

    for any lack of information or lack of understanding.

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    Appendix B

    Sinus and Fistula

    Sinus.A sinus is a track leading from a focus of suppuration to a cutaneous or mucous surface. It usually

    represents the path by which the discharge escapes from an abscess cavity that has been prevented fromclosing completely, either from mechanical causes or from the persistent formation of discharge which must

    find an exit. A sinus is lined by granulation tissue, and when it is of long standing the opening may be dragged

    below the level of the surrounding skin by contraction of the scar tissue around it. As a sinus will persist until

    the obstacle to closure of the original abscess is removed, it is necessary that this should be sought for. It may

    be a foreign body, such as a piece of dead bone, an infected ligature, or a bullet, acting mechanically or by

    keeping up discharge, and if the body is removed the sinus usually heals. The presence of a foreign body is

    often suggested by a mass of redundant granulations at the mouth of the sinus. If a sinus passes through a

    muscle, the repeated contractions tend to prevent healing until the muscle is kept at rest by a splint, or put

    out of action by division of its fibres. The sinuses associated with empyema are prevented from healing by the

    rigidity of the chest wall, and will only close after an operation which admits of the cavity being obliterated. Inany case it is necessary to disinfect the track, and, it may be, to remove the unhealthy granulations lining it, by

    means of the sharp spoon, or to excise it bodily. To encourage healing from the bottom the cavity should be

    packed with bismuth or iodoform gauze. The healing of long and tortuous sinuses is often hastened by the

    injection of Beck's bismuth paste. If disfigurement is likely to follow from cicatricial contractionfor example,

    in a sinus over the lower jaw associated with a carious tooththe sinus should be excised and the raw

    surfaces approximated with stitches.

    A fistulais an abnormal canal passing from a mucous surface to the skin or to another mucous surface. Fistul

    resulting from suppuration usually occur near the natural openings of mucous canalsfor example, on the

    cheek, as a salivary fistula; beside the inner angle of the eye, as a lacrymal fistula; near the ear, as a mastoid

    fistula; or close to the anus, as a fistula-in-ano. Intestinal fistul are sometimes met with in the abdominal

    wall after strangulated hernia, operations for appendicitis, tuberculous peritonitis, and other conditions. In the

    perineum, fistul frequently complicate stricture of the urethra.

    Fistul also occur between the bladder and vagina (vesico-vaginal fistula), or between the bladder and the

    rectum (recto-vesical fistula).

    The treatmentof these various forms of fistula will be described in the sections dealing with the regions in

    which they occur.

    Congenital fistul, such as occur in the neck from imperfect closure of branchial clefts, or in the abdomenfrom unobliterated ftal ducts such as the urachus or Meckel's diverticulum, will be described in their proper

    places.

    From (http://www.manual-of-surgery.com/content/0021-Sinus-and-Fistula.html)

    DONE !