3
Supplemental Figure 2 A B C D A cquisition D ay 1 2 3 4 5 6 Sw im Tim e (s)to Platform 0 15 30 45 60 Saline Saline + xR T M nP M nP + xR T (a) R eversal D ay 7 8 9 10 11 12 Sw im Tim e (s)to Platform 0 15 30 45 60 Saline Saline + xR T M nP M nP + xR T (b) Train STM LTM Preference Score for N ovelO bject -0.2 0.0 0.2 0.4 0.6 0.8 1.0 Saline Saline + xR T M nP M nP + xR T # ^ Train STM LTM Tim e (s)Spentw ith O bjects 0 15 30 45 60 75 90 Saline Saline + xR T M nP M nP + xR T (a) (b)

Supplemental Figure 2

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Supplemental Figure 2. A B. Saline Saline/RT MnP MnP /RT. Saline Saline/RT MnP MnP /RT. C D. Saline Saline/RT MnP MnP /RT. Saline Saline/RT MnP MnP /RT. Supplemental Figure 2. - PowerPoint PPT Presentation

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Page 1: Supplemental Figure 2

Acquisition

Day

1 2 3 4 5 6

Sw

im T

ime

(s)

to P

latf

orm

0

15

30

45

60 SalineSaline + xRTMnPMnP + xRT

(a)

Reversal

Day

7 8 9 10 11 12

Sw

im T

ime

(s)

to P

latf

orm

0

15

30

45

60SalineSaline + xRTMnPMnP + xRT

(b)

Train STM LTM

Pre

fere

nce

Sco

re f

or

No

vel O

bje

ct

-0.2

0.0

0.2

0.4

0.6

0.8

1.0

Saline Saline + xRT MnP MnP + xRT

#̂

Train STM LTM

Tim

e (s

) S

pen

t w

ith

Ob

ject

s

0

15

30

45

60

75

90

Saline Saline + xRT MnP MnP + xRT

(a) (b)

Supplemental Figure 2

A B

C D

SalineSaline/RTMnPMnP/RT

SalineSaline/RTMnPMnP/RT

SalineSaline/RTMnPMnP/RT

SalineSaline/RTMnPMnP/RT

Page 2: Supplemental Figure 2

Training STM LTM Average Velocity0

0.5

1

1.5

2

2.5

3

3.5

4

SalineSaline/RTMnPMnP/RT

Ave

rage

Vel

ocit

y (c

m/s

)

Training STM LTM Average Distance0

200

400

600

800

1000

1200

SalineSaline/RTMnPMnP/RT

Ave

rage

Dis

tanc

e (c

m)

E

F

Supplemental Figure 2

Page 3: Supplemental Figure 2

Cued Test

Saline Saline + xRT MnP MnP + xRT

% T

ime

Fre

ezin

g

0

20

40

60

80

100Before Conditioning ToneConditioning Tone

Context Test

Salin

e

Salin

e +

xRT

MnP

MnP +

xRT

% T

ime

Imm

ob

ile

0

20

40

60

80

100

(a) (b) G H

Supplemental Figure 2

Saline Saline/RT MnP MnP/RT

Salin

e

Salin

e/RT

MnP

MnP/RT


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