Suplements of Rosacea dermatitis

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    SuplementsBUSINESS PLAN PRESENTATION

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    Drugs used on topical medications and cosmetics: Drugs Taken Oral or Inhale

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    Drugs used on topical medications and cosmetics: Drugs Taken Oral or Inhale

    Amino benzoic Acid (PABA) used in sunscreen cosmetics

    Avobenzone (aka butyl methoxydibenzoylemethane, Parsol

    1789) used in sunscreens

    Benzocaine

    Benzoyl Peroxide (used in acne medications and cosmetics)

    Benzyl Nicotinate

    Capsaicin

    Corticosteroids Diethanolamine p-methoxycinnamate (sunscreens)

    Dicxybenzone

    Esthylhexyl p-methoxycinnamate

    Ethyl Salicylate

    Glycol salicylate

    Hydrocortisone

    Hydrogen Peroxide

    Hydroquinone - pigment lightening agent

    Methyl nicotinate

    Methyl salicylate Octinoxate (formerly octyl methoxycinnamate) - sunscreen

    Oxybenzone

    Resorcinol

    Retinoids (tretinoin, Renova, Retin-A, Avita, Differin)

    Salicylic Acid

    Sulisobenzone

    Topical antihistamines Trichloroacetic acid

    Triclosan

    Alcohol (ethanol, spirits)AminophyllinAnabolic steroidsAngiotensin-converting enzyme inhAspartame (NutraSweet)AspirinCalcitoninCalcium channel blockers

    CocaineCortiscosteroidsCorticotrophin-releasing hormoneIbuprofenLovastatin (Mevacor)MarijuanaNaproxen (Naprosyn)Niacin (aka Vitamin B3)NicotineNifedipine

    Nitrates (food related)NitroglycerinOpioid narcotics (morphine, codeiDemerol, Darvon, Dolophine, VicoProgesteroneSimvastatin (Zocor)Sodium monoglutamate (food relaTheophyllineVancomycinVasodilators

    Viagra

    Drugs used in Cosmetics

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    Drugs used in Cosmetics

    2-bromo-2-nitropropane-1,3-diolAcetoneAlbumin (egg whites)Alcohol (volatile only: ethanol, ethyl alcohol, isopropyl alcohol,isopropanol, SD alcohol, alcohol denatured)AlgaeAlpha hydroxy acids and salts (including but not limited to:glycolic acid, lactic acid, citric acid, malic acid, tartaric acid,

    sodium glycolate, ammonium glycolate, sodium lactate,ammonium lactate)AmmoniaArachidonic acidArnica oilAscorbic Acid (vitamin C)Balsam PeruBarleyBay laurel oilBayberry oil

    BentoniteBenzalkonium chlorideBenzophenonesBergamot oilBitter orange oilBlack pepper oilBromelainCaffeineCamphor oilCaCayenne

    Cetrimonium bromidepsicum

    Chamomile oilCinnamic aldehydeCinnamon oilClove oilCocoa butterCoriander oil (from the seeds of Cilantro)Corn extractCornstarch

    Diazolindinyl ureaDMAEDMDM hydantoinEucalyptus oilFennel oil or extractFir needle oilFragrance (synthetic or natural)Gernaiol (found in palmarosa oil, geranium citronella oil, rose oil and many other essentaromatherapy and skin care products, sham

    GingerGinsengGranular exfoliants (including Loofah, oatmeshells, salt, sand, pumice, diatomaceous eacrystals, jojoba beads, polyethylene beads)Grapefruit oil or extractImidazolidinyl ureaIodineLanolinLecithin

    Lemon oil

    Drugs used in Cosmetics II

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    Drugs used in Cosmetics II

    Lemongrass oilLime oilMannanMentholMicaMontmoriloniteMustardMyrrh OilNettleNiacin (vitamin B3)Nutmeg OilOak moss extractOatsOrange oilPABA (sunscreen)Papain (enzyme found in digestive remedies, skin exfoliating cosmetics)Papaya extract (found in many cosmetics)Peanut oilPennyroyalPeppermintPhenolPhenoxyethanolPhosphatidylcholinePine oilPropylene glycolQuarternium-15Retinol (vitamin A)Rosemary oil

    Rue oilSaccharomyces (yeast)Saccharomyces lysateSage essential oilSalicylic acid (BHA)Sandalwood oilSeaweedSesame oilSodium C14-16Sodium laureth sulfateSodium lauryl sulfateSoy proteinSpearmint oilStearic acidStearalkonium chlorideSulfurTangerin oilTEA-lauryl sulfateTea tree oil (maleleuca)Thyme essential oilTocopherolTocopheryl nicotinateTurmeric oilVanilla extract or oilWintergreenWitch hazel (when in alcohol or propYlang-ylang oil

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    Environmental Triggers: Atmosphere: history of sun burns (impairs immune s

    carbon monoxide/dioxide, Bacteria: history of acne

    Airborne: Proximity to heavy industrial complex, fac

    mining, freeways, polluted water, dry cleaning fac

    Parasites: Demodex mites Inner atmosphere: household dust, sick-building syn

    lead, radon, asbestos, house hold cleansers and sp

    insecticides, aromatherapies and room deodorize

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    Corticosteroid mechanism

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    Corticosteroid mechanism Anti-Inflamation

    Prevent margination (leucocytes & monocytes adherent)

    Inhibit Chemotaxis

    Vasoconstriction

    Decreasing membran permeability

    Inhibit releasing of toxic agent extravasation serum , swelling Immunosupresant

    Differentiation of limphoid cells

    Lysis of B lymphocytes Inhibit lymphocines activities

    Antimytotic

    Supress cells proliferation

    Decrease RNA transcription, DNA synthesis, DNA reparation

    Skin: keratinocytes, fibroblast collagen & fibril

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    In T-cells, activation of thnormally increases intracwhich acts via calmodulcalcineurin. Calcineurin tdephosphorylates the tra

    factor NF-AT (nuclear facT-cells), which moves to tthe T-cell and increases tgenes coding for IL-2 andcytokines. Tacrolimus predephosphorylation of NFTacrolimus reduces pept

    isomerase activity by binimmunophilin FKBP12 (FKprotein) creating a new FKBP12-FK506 complex ininhibits calcineurin thus inlymphocyte signal transdtranscription

    http://en.wikipedia.org/wiki/Calcineurinhttp://en.wikipedia.org/wiki/FKBP12http://en.wikipedia.org/wiki/Calcineurinhttp://en.wikipedia.org/wiki/Lymphocytehttp://en.wikipedia.org/wiki/Lymphocytehttp://en.wikipedia.org/wiki/Calcineurinhttp://en.wikipedia.org/wiki/FKBP12http://en.wikipedia.org/wiki/Calcineurin