Sugar Shifting:

Optimising Food Systems Resilience In Transition to Low Sugar Consumption

A multi-actor workshop held March 13, 2017 at the University of Leeds

Dr. J. Bernadette Moore

Associate Professor of Obesity

N8 Pump Priming Presentation

University of Leeds, February 15, 2018

Obesity and Non-alcoholic Fatty Liver Disease (NAFLD)

What are the dietary, genetic and molecular factors that influence NAFLD pathogenesis?

Moore, Maldonado In preparation

Proteomics and Multi-scale Modelling of Hepatic Lipogenesis

Fisher et al. (2013) Bioinformatics

Fisher et al. (2014) World J Gastroenterology

Spanos & Moore (2016) Methods in Molecular Biology

Maldonado et al. (2017) CPT: Pharmacometrics & Systems Pharmacology

Spanos, Maldonado, Fisher et al. (2018) Proteome Sciences

Maldonado, Fisher et al. Invited to revise & resubmit, NPJ Systems Biology & Applications

Scrutinized because:

• Intakes have risen in parallel with obesity

• Metabolized differently by liver• At high experimental doses

exacerbates obesity and NAFLD

BUT

• Experimental doses far exceed what we consume

• Rarely consume single sugar in isolation

• When excess energy controlled for no differential effect

Fructose:

The New F Word

Moore et al. (2014) Nutrients

Moore & Fielding B (2016) Curr Opin Clin Nutr Metab Care

Obesity & Sugar Consumption

OECD Obesity Update 2014: www.oecd.org/health/obesity-update.htm

RJ Johnson et al. 2007 Am Soc Clin Nutr

Moore & Fielding (2016) Curr Opin Clin Nutr Metab Care

Evidence

• Causal link between high-sugar diet and obesity and dental caries

• The role of sugar-sweetened beverage consumption in development of

diabetes

Recent Guidelines from UK, US, WHO Unanimously Recommend Cutting Consumption of Added Sugars

Moore & Fielding (2016) Curr Opin Clin Nutr Metab Care

Sugar Consumption

Childhood Obesity

• 42 million children under the age of 5 were overweight or obese in 2013.

Lobstein et al (2015) Lancet 385: 2510–20

‘Obesity is preventable.’

- WHO

25.0%24.2%

22.7%21.2%

19.3%17.8%

16.0%15.0%

13.7%

11.5%12.0%11.2%

10.3% 9.7%9.0%

8.3% 7.6% 7.0% 6.8%5.7%

0%

5%

10%

15%

20%

25%

30%

Mostdeprived

Leastdeprived

Ob

esit

y p

reva

len

ce

Index of Multiple Deprivation 2010 decile

Year 6

Reception

Child obesity: BMI ≥ 95th centile of the UK90 growth reference

National Child Measurement Programme 2014/15

Science to PolicyMarch 2015

July 2015

October

2015

August

2016

October

2016 March

2017

SugarPolicy

Popkin & Hawkes (2016) Lancet Diabetes Endocrinol 2016; 4: 174–86

Increase in LocalInterventions

Brighton & Hove

(University of Brighton)

Bristol

Lewisham

Greenwich

Exeter

Tipping Point?

Tipping Point?

FAO

USDA

Taylor RD

(2016)

Agribusiness &

Applied

Economics

Report 751

FRC Policy Briefs, 2015

‘a better food system would begin to wean the

world off massive sugar production and

consumption’

‘surely, more attention ought to be given to

chart a better form of employment and land

use; better health and environment’

‘If consumption falls to 5% likely to impact ACP’

Sugar Shifting:

Optimising UK Food Systems Resilience in

Transition to Low Sugar Consumption

O5: Multi-actor

Stakeholder Engagement

Knowledge Exchange

Consumers Producers

O1: Household

Purchasing

O2: Determinants of

Food Choice

O3: Environmental

Impacts

O4: Producer

Communities

Industries Policymakers

Multi-actor workshop: Nutrition, public health, consumer behaviour, environmental sustainability and the political economy

Sugar Shifting:

Optimising UK Food Systems Resilience in

Transition to Low Sugar Consumption

March 13th, University of Leeds

Indicators for socially responsible

consumption and production:

a test case with sugarcane

Questions?