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Dr Simon Thornley (Auckland Regional Public Health Service) Sugar, dental caries and acute rheumatic fever: what is the link?

Sugar, Dental caries and acute rheumatic fever: what is the link? › wellington › otago711234.pdf · • Roger Marshall, University of Auckland • Katie Bach, Paediatric Dentist,

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Page 1: Sugar, Dental caries and acute rheumatic fever: what is the link? › wellington › otago711234.pdf · • Roger Marshall, University of Auckland • Katie Bach, Paediatric Dentist,

Dr Simon Thornley (Auckland Regional Public Health Service)

Sugar, dental caries and acute

rheumatic fever:

what is the link?

Page 2: Sugar, Dental caries and acute rheumatic fever: what is the link? › wellington › otago711234.pdf · • Roger Marshall, University of Auckland • Katie Bach, Paediatric Dentist,

Overview

• How could sugar be related to dental caries?

• A cohort study

• Results

• Conclusion

• What next?

• A new strategy for preventing rheumatic fever?

Page 3: Sugar, Dental caries and acute rheumatic fever: what is the link? › wellington › otago711234.pdf · • Roger Marshall, University of Auckland • Katie Bach, Paediatric Dentist,

The hypothesis

Page 4: Sugar, Dental caries and acute rheumatic fever: what is the link? › wellington › otago711234.pdf · • Roger Marshall, University of Auckland • Katie Bach, Paediatric Dentist,

How could sugar cause rheumatic fever?

Page 5: Sugar, Dental caries and acute rheumatic fever: what is the link? › wellington › otago711234.pdf · • Roger Marshall, University of Auckland • Katie Bach, Paediatric Dentist,

Statistical evidence

of association?

Page 6: Sugar, Dental caries and acute rheumatic fever: what is the link? › wellington › otago711234.pdf · • Roger Marshall, University of Auckland • Katie Bach, Paediatric Dentist,

The study

Page 7: Sugar, Dental caries and acute rheumatic fever: what is the link? › wellington › otago711234.pdf · • Roger Marshall, University of Auckland • Katie Bach, Paediatric Dentist,

Compare children, by caries P(ARF | Decayed teeth) = P(ARF | Good teeth)

Page 8: Sugar, Dental caries and acute rheumatic fever: what is the link? › wellington › otago711234.pdf · • Roger Marshall, University of Auckland • Katie Bach, Paediatric Dentist,

Other explanations…

Age

Gender

Ethnic group

Socioeconomic status

Spurious

Page 9: Sugar, Dental caries and acute rheumatic fever: what is the link? › wellington › otago711234.pdf · • Roger Marshall, University of Auckland • Katie Bach, Paediatric Dentist,

Cohort study

• 20,033 Māori and Pacific children (ARDS)

• Aged 5 to 6 years

• Free of chronic disease at baseline

• Exposure: dental caries

• Outcome: rheumatic fever (n = 96)

Page 10: Sugar, Dental caries and acute rheumatic fever: what is the link? › wellington › otago711234.pdf · • Roger Marshall, University of Auckland • Katie Bach, Paediatric Dentist,

Results

Page 11: Sugar, Dental caries and acute rheumatic fever: what is the link? › wellington › otago711234.pdf · • Roger Marshall, University of Auckland • Katie Bach, Paediatric Dentist,

Summary • Teeth provide an indicator of cumulative

exposure to sugar

• Caries strongly linked to ARF incidence

• Limiting sugar may reduce disease incidence

• Intervention study would be next step

Page 12: Sugar, Dental caries and acute rheumatic fever: what is the link? › wellington › otago711234.pdf · • Roger Marshall, University of Auckland • Katie Bach, Paediatric Dentist,

Acknowledgements • Roger Marshall, University of Auckland

• Katie Bach, Paediatric Dentist, ADHB

• Pauline Koopu, Dentist, ADHB

• Gary Reynolds, Medical Officer, ARPHS

• Gerhard Sundborn, University of Auckland

• Dean Papa, CMDHB

• Julia Peters, ARPHS

• Satha Kanagaratnam, ARDS.