NOTE: Weights are from random effects analysis

Overall (I-squared = 72.5%, p = 0.000)

Zisman E

Triulzi DJ

STUDY

McGill N

Licker M

Ho¨hn L

Licker M

Mahoori A

Momeni M

Jalali A

Casati V

Nuttall GA

Casati V

Virmani S

Kochamba GS

Dietrich W

Vedrinne C

Helm RE

Herregods L

2009

1995

YEAR

2002

2007

2002

2005

2009

2012

2008

2002

2000

2004

2010

1996

1989

1992

1996

1997

15/27

5/18

ANH

29/84

6/19

12/36

17/41

23/54

5/30

17/50

32/102

5/32

2/50

84/88

24/50

39/50

19/30

8/45

14/39

17/35

10/28

CONTROL

43/84

6/21

12/41

14/39

35/47

3/31

46/50

34/100

15/43

10/50

97/100

35/50

48/50

23/30

23/45

20/32

0.74 (0.63, 0.88)

1.14 (0.71, 1.85)

0.78 (0.32, 1.90)

RR (95% CI)

0.67 (0.47, 0.97)

1.11 (0.43, 2.85)

1.14 (0.59, 2.21)

1.16 (0.66, 2.01)

0.57 (0.40, 0.81)

1.72 (0.45, 6.58)

0.37 (0.25, 0.55)

0.92 (0.62, 1.37)

0.45 (0.18, 1.10)

0.20 (0.05, 0.87)

0.98 (0.93, 1.04)

0.69 (0.49, 0.96)

0.81 (0.69, 0.95)

0.83 (0.59, 1.16)

0.35 (0.17, 0.69)

0.57 (0.35, 0.94)

100.00

5.83

2.66

Weight

7.37

%

2.44

4.05

5.01

7.50

1.36

6.91

6.89

2.62

1.16

11.10

7.66

10.22

7.72

3.85

5.62

0.74 (0.63, 0.88)

1.14 (0.71, 1.85)

0.78 (0.32, 1.90)

RR (95% CI)

0.67 (0.47, 0.97)

1.11 (0.43, 2.85)

1.14 (0.59, 2.21)

1.16 (0.66, 2.01)

0.57 (0.40, 0.81)

1.72 (0.45, 6.58)

0.37 (0.25, 0.55)

0.92 (0.62, 1.37)

0.45 (0.18, 1.10)

0.20 (0.05, 0.87)

0.98 (0.93, 1.04)

0.69 (0.49, 0.96)

0.81 (0.69, 0.95)

0.83 (0.59, 1.16)

0.35 (0.17, 0.69)

0.57 (0.35, 0.94)

100.00

5.83

2.66

Weight

7.37

%

2.44

4.05

5.01

7.50

1.36

6.91

6.89

2.62

1.16

11.10

7.66

10.22

7.72

3.85

5.62

Favours [ANH] Favours [Control]

1.0461 1 21.7