STUDY GUIDE - UQPMS – UQ Premedical · PDF fileBIOL1040 Cells to Organisms

STUDY GUIDE 2012

Biomedical Sciences Major

PMS SOCIETY FOR UNIVERSITY OF QUEENSLAND PREMEDICAL STUDENTS

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President’s Foreword ........................................................................................................................................................ 2

Academic Officers’ Foreword ............................................................................................................................................ 3

Disclaimer .......................................................................................................................................................................... 4

BIOL1020 Genes, Cells & Evolution ................................................................................................................................... 5

PSYC1030 Introduction to Psychology .............................................................................................................................. 7

CHEM1010 Fundamentals of Chemistry ........................................................................................................................... 9

CHEM1020 Chemistry for Science and Engineering ....................................................................................................... 11

BIOL1040 Cells to Organisms .......................................................................................................................................... 13

STAT1201 Analysis of Scientific Data .............................................................................................................................. 16

BIOM2011 Integrative Cell and Tissue Biology ............................................................................................................... 18

BIOM2012 Systems Physiology ....................................................................................................................................... 20

BIOL2200: Cell Structure & Function .............................................................................................................................. 22

BIOM2402 Principles of Pharmacology........................................................................................................................... 24

MICR2000: Microbiology and Immunology .................................................................................................................... 26

Contents


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Welcome to the Biomed Guide for 2012. It is my pleasure to present to you our first edition of the guide brought to you by brand new University of Queensland Premedical Society (PMS). The guide, being our first major academic initiative, will work in synergy with our other major events throughout the year.

The idea of the guide is to give BSc provisional entry and biomedical major students alike the ability to be more informed about their subject choices. Past students have noted the before beginning the MBBS program it is important for students to expand their horizons and peruse what they are really interested in. Although the university sets the courses that you must undertake during your program, there is some flexibility. Notably, students have the ability to select out of a large list of 2nd and 3rd year level subjects that count towards the course requirements. Do you want to undertake genetics or pharmacology, microbiology or systems physiology? This guide will help you make decisions like these in an informed way.

For those of you that don’t know, PMS was founded in August 2011 and didn’t begin full operation until 2012. So when you consider how well you use our resources, you are defining how the society will progress forward into the future. Please do take advantage of the society, and for you first years forward on any questions you may have to us and we will get them answered.

In addition to the Biomed Guide, all PMS members have access to the SUSS course notes database. This will be rolled out during semester one this year.

Many of you will have heard rumours that the entry pathway for UQ Medicine will change in the future. Currently this is the most academic issue relevant to us currently. PMS will be perusing the issue to find out more information for you. Officially, UQ has stated that they are considering replacing the MBBS program with an MD. It is important to note that no change has been officially announced.

On behalf of the University of Queensland Premedical Society,

Anthony Deacon President University of Queensland Premedical Society

President’s Foreword


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Academic Officers’ Foreword

An initiative from the University of Queensland Premedical Society and its Academic Officers, this subject guide aims to help premedical students majoring in biomedical science in their future subject selections. It provides useful previews into the major courses as well as insights in to what the course experience will be like. It will be very advantageous to have a future study plan, and this guide will hopefully be a useful tool in shaping that plan.

Within this subject guide you will not only find course descriptions, but also detailed explanations of the course’s assessments and marking schemes. This will elucidate the course expectations before you delve into it. To a certain degree it will let you gauge how much of the course content will be of specific interest to you, for more information on assessment specifics and course content we still recommend that you consults the electronic course profile.

In addition, the guide also presents to you a ’Student Review’ section. This is a summary of what students who took the course recently thought were the advantages and disadvantages, as well as tips for taking the course. This will give you a new perspective on the course, and help you draw from the experiences of past students. It is something that you will not be able to find on any resource or course guide provided by the school or the university.

As much as this the first edition of the guide, we have put a lot of thought and effort into presenting it to you. We are confident that it will become a valuable resource for members of UQPMS when it comes to selecting courses or finding out more about the courses you have selected to take.

We wish you the best in your future academic endeavours,

Dilum Ekanayake Mathuja Bavan Shiney (Soo Jung) Seo

Academic Officers University of Queensland Premedical Society


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Disclaimer The information provided in this guide is correct as of February 2012, with adjustments made as knowledge of them has been acquired. Due to the likelihood of changes being made to the course structures at the discretion of the course coordinators for courses in this guide, no responsibility is taken by PMS or the authors for the accuracy and correctness of the course information provided herein. As such it is advised that the reader consult the electronic course profile for more detailed information on assessment details and course expectations if unsure. For further enquiries feel free to direct them to any of the academic officers at [email protected]. All efforts will be made to address queries forthwith.

mailto:[email protected]


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BIOL1020 Genes, Cells & Evolution

Course Information Offered: Semester 1 & Semester 2 Course Coordinators: Dr Paul Ebert (semester 1) Dr Cynthia Riginos (semester 2) Prerequisites: None Recommended prerequisites: None

Course Description The fundamentals of cellular biology are covered in this course, and it introduces students to the various concepts crucial to modern cellular biology ranging from basic cell structure to genetic inheritance and evolution. This course explains basic biological concepts such as genetics and cell structure as they relate to evolution. Examples in lectures draw on a wide range of experimental systems with specific reference to human biology whenever possible. Practical exercises utilise experimental model organisms and computational research tools to allow students to gain the most authentic research experience that can be achieved in a first year course.

x Module 1 – Cell Biology o This module looks at cells and cellular organisation. Cells make up all living organisms and there are

a multitude of types of cells. This module also looks at the molecules that make up cells, their various structures and what they are used for within cells.

x Module 2 – Molecular Genetics o The molecular genetics unit will go into more detail about DNA, its structure and how it is the

biological unit of inheritance. It will delve to the central dogma of biology. x Module 3 – Prokaryotic genetics

o This module will introduce students to the basic genetics of bacteria, viruses and other prokaryotes. This module is very relevant to the practical classes and to future research interests as it delves into present technologies used in genetics that manipulate DNA and RNA.

x Module 4 – Eukaryotic genetics o Drawing from the information in the prokaryotic genetics module, this module introduces concepts

of eukaryotic and Mendelian genetics. This module also goes into concepts of crossing and pedigree analysis to identify the inheritance of traits.

x Module 5 – Genomics o This is a relatively new area of research and this module will present some of the cutting edge

research that is currently being carries out.

Student Review Advantages:

x This course is the perfect introduction to cellular biology for those who have not studied it previously. x Lectures are logically sequenced and easy to follow. They are well staged and build on each other so

students should not get lost or confused. x With the various opportunities to earn credits and partake in research techniques etc., BIOL1020 can be an

interesting and engaging subject which is not difficult to do well in. x Lectures and practicals run in tandem and build on each other so students can view the practical applications

of theoretical knowledge gained from the lectures.


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x The materials covered in this course provide a crucial foundation for future studies into molecular or cellular biology and biological research.

Disadvantages: x Being an introductory course to biology, those who have previously studied biology at a high school level

may find this course repetitive and simple. x The wide range of possible credits and a bid to earn all of them will at times seem difficult, tedious and time

consuming. However this is easily achieved by good time management. x Practicals may seem simple and tedious at the time but these help with understanding certain concepts. x The blog article and presentation instructions and expectations can be confusing, hence it is important not

to stress and ask the prac tutors. Tips:

x Shop around with the various PASS tutes until you find tutors who suit your learning style. x If you are stuck make sure to talk to your tutors and lecturers, they will be of assistance where possible. x Make sure to keep an eye open on my.uq or the library website for past exams closer to your final exam

date. x This course can involve a lot of write learning for a first year subject. Mnemonics/acronyms have worked

well for people in the past.

Assessment x Practical Assignment (34%)

o The various practical assignments are composed of weekly pop quizzes on theory learned in previous practical lessons and in lectures

x Blog article and presentation (6%) o The blog article and presentation will be held during normal practical sessions and requires students

to read up on recent articles into genetics research and write up a blog post and present this to their respective practical groups.

x Mid Semester Exam (15%) o This is a series of multiple choice questions to be completed on a computer during your normal

times. x End of semester Exam (45%)

o This exam must be passed with a grade or 50% or higher in order to pass the course. � 10 minutes perusal � 120 minutes working time � Multiple choice, short answer and problem solving questions


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PSYC1030 Introduction to Psychology

Course Information Offered: Semester 1, Semester 2 & Summer Semester Course Coordinators: Prof Virginia Slaughter Prerequisites: None Recommended prerequisites: None

Course Description The fundamentals of psychology are covered in this course, and it introduces students to the various aspects of modern psychology ranging from research to clinical and sports psychology. Focussing on topics such as the development of thought, language, personality as well as social aspects such as communication and altruism, this course gives you the opportunity to partake in both classical and state of the art research. During normal semesters, it is composed of 2 lecture hours and 1 tutorial hour, whilst in summer it is composed of 4 lecture and 2 tutorial hours.

x Week 1- Introduction to PSYC1030 x Week 2- Persuasion x Week 3- Prejudice/Stereotyping x Week 4- Nonverbal Communication x Week 5-Infancy x Week 6- Attachment x Week 7- Social Development x Week 8- Piaget’s Theory x Week 9- Attitudes x Week 10- Organisational Psychology x Week 11- Health Psychology x Week 12- Introduction to Psychological Therapies


x This course is the perfect introduction to psychology for those who have not studied it previously. x Lectures are logically sequenced and easy to follow. Modules and concepts build on each other while

covering a broad range of topics. x With the various opportunities to earn credits and partake in research etc. PSYC1030 is an interesting and

engaging subject which is not difficult to do well in. x It is a great way to break up a semester with more challenging and time consuming second or third year

courses as long as it is not taken too lightly. Disadvantages:

x Being an introductory course to psychology, those who have previous experience in the area of psychology may find it repetitive and simple.


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x Earning the 6 research credits may at sometimes seem tedious and time consuming however they could be a crucial determinant in your final grade.

x It is easy to zone out in lectures because it may seem like the lecturers present you with one concept and spend ten minutes going through examples reiterating a topic you understood from the first example

Tips: x If you are stuck make sure to talk to your tutor and lecturer; the tutors know what they are talking about and

will no doubt be able to answer and questions you may have. x Do not skip the draft process for your assignment, as the feedback will be valuable and will help boost your

final grade for that assignment. x Make sure to keep an eye open on myUQ or the library website for past exams closer to your final exam

date.

Assessment x Research participation (6%)

o This assessment is non-compulsory, to complete it the student my partake in 6% research studied available at UQ. Each study contributes 1%.

x Online Quiz (9%) o To be completed at your leisure and is an open book mid-semester exam. It is a relatively easy way

to get course credit. x Draft Introduction (0%)

o The draft introduction is not marked formally and does not contribute to the final grade but it is very useful for doing well in the assignment.

x Lab report (35%) o Written using information obtained in the tutorials and handed in through Turnitin.

x End of semester exam (50%) � Multiple choice questions � 10 minutes perusal � 120 minutes working time


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Course Information Offered: Semester 1 Course Coordinators: Prof. Mary Garson & Dr Lawrence Lo Prerequisites: None Recommended Prerequisites: Senior Chemistry, or CHEM1090

Course Description This course provides a basic introduction to chemistry. It introduces the fundamental ideas in chemical bonding, and how these concepts are applied in organic molecules. Classification of organic molecules, reactivity of organic molecules and the implications of the three dimensional shape of these molecules are discussed. Finally, transition metal chemistry is also introduced, with focus on the interesting properties of these metals.

x Bonding o Basic chemistry concepts, including types of bonds, intermolecular and intramolecular forces etc.

x Organic Chemistry o This section contains the most content in this course. Starts from classifying and naming organic

compounds, before describing several different reaction classes including nucleophilic substitution and elimination.

x Transition Metal Chemistry o Focuses on the properties of transition metal compounds, including formation of coloured solutions,

isomerism, multiple oxidation states and the coordination chemistry of transition metal complexes.


x Initially, the content is purely revision of grade 12 chemistry, so the transition into this subject should be comfortable. In most topics the complexity goes just beyond grade 12 chemistry, so that some content matter is new, without being overly challenging.

x Most of the organic chemistry module simply needs to be memorised – the lecturers do not require students to understand exactly why each reaction occurs in depth (however, be careful and note which reaction types do need to be understood in depth)

x There is plenty of access to practice questions through PASS worksheets and CMTs. Disadvantages:

x Certain parts of the course, in particular the reactions and reactivity section, contain a lot of content to be learnt. In contrast, some of the reaction chemistry can be difficult to grasp conceptually. Being able to learn in different ways is important.

x This course is amongst the hardest first year courses. x Those who didn’t complete senior chemistry (which is a recommended prerequisite for this subject) may

need to work hard at the beginning of semester to grasp basic concepts, which are covered quite quickly in the first few weeks.

CHEM1010 Fundamentals of Chemistry


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Tips: x Often, the complex chemistry behind the reactions taught in this subject is beyond the scope of first year

chemistry, so if the lecturer states that you simply need to know how to write out a particular reaction mechanism, don’t waste time trying to figure out ‘why’ it happens.

x PASS is particularly important in this subject, as the worksheets given provide excellent practice for both the exam and the CMTs. As mentioned above, there are a lot of reactions to learn, and possibly the best way to handle them is to learn and understand the trends and explanations the lecturers give, instead of rout learning every single reaction type in the lecture notes. For example, first learn how alkene addition reactions occur in general, before learning the different specific mechanisms for addition of water, hydrogen gas, halogens etc.

Assessment: x Practical Assessment (25%)

o There will be five practical sessions throughout semester- a set of questions related to the practical must be answered and submitted by the end of the three hour session.

x Lab Quiz (5%) o This will be based on the practicals completed throughout semester.

x Computer Quizzes (10%) o There will be three of these throughout the semester, each worth 3.3%

x Mid-semester Exam (20%) o Multiple choice and short answer questions o 60 mins + 10 mins perusal

x EOS (40%) o Multiple choice and short answer questions o 120 mins + 10 mins perusal


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Course Information Offered: Semesters 1 & 2 Course Coordinators: Assoc Prof Mark Riley (semester 1), Dr Gwen Lawrie (semester 2) Prerequisites: None Recommended Prerequisites: Senior Chemistry, or CHEM1090

Course Description This course covers the side of introductory molecular chemistry not covered in CHEM1010. The course starts with thermochemistry- delving into enthalpy and spontaneity. The concept of chemical equilibrium is taught, followed by acid/base chemistry. Finally, important concepts in kinetics and electrochemistry are also taught.

x Module 1: Gases, Condensed Phases, Thermochemistry, Entropy & Free Energy. o Covers basic gas laws, intermolecular interactions, enthalpy and spontaneity

x Module 2: Equilibria, Phase Changes, Solutions, Electrochemistry. o Covers vapour pressure, gibbs free energy, ion solubility, osmosis, and an introduction to redox

reactions x Module 3: Applications of Equilibria: Acids & Bases, Kinetics.

o Covers basics of acids and bases, including calculating pH, strong and weak acids and bases, isoelectric points, buffer solutions and titrations. Also covers rate laws, reaction mechanisms and other basic kinetics topics


x A large amount of content in each of the three modules is covered in senior chemistry, and the remaining content simply adds to concepts you should already understand. Having the mid-semester exam not only gives you feedback on your progress in the subject, but also provides motivation to keep track of the lectures throughout the first half of semester too.

Disadvantages: x A lot of the basic background for the modules (e.g. basic thermochemsitry in module 1) is covered

quickly, which might present a challenge for those who didn’t take senior chemistry. Tips:

x For those who didn’t complete grade 12 chemistry, the best way to tackle the subject is to identify and understand the basic concepts key to each of the three modules (e.g. entropy, equilibrium, acid/base definitions) early on, before attempting to learn the details in each module.

x As many senior high school students used graphics calculators in chemistry, it is recommended that you spend time familiarising yourself with using a scientific calculator efficiently.

CHEM1020 Chemistry for Science and Engineering


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Assessment: x Computer Based Assessment- Computer Quizzes (10%)

o 3 quizzes, spaced throughout the semester x Mid-semester Exam (20%)

o Mixture of multiple choice and short answer questions o 60 mins + 10 mins perusal

x Practicals (25%) o A report will be submitted at the end of each practical session

x Computer Based Assessment- Lab Quizzes (5%) x EOS (40%)

o Mixture of multiple choice and short answer questions o 120 mins + 10 mins perusal


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BIOL1040 Cells to Organisms

Course Information Offered: Semesters 1 & 2 Course Coordinators: Assoc Prof Lesley Lluka & Dr Prasad Chunduri Prerequisites: None Recommended Prerequisites: None

Course Description This course covers fundamental biological concepts that allow organisms to function. Students are introduced to basic cellular transport and signalling mechanisms, neuronal structure and function, motor mechanisms and locomotion, circulation and gas exchange, and the endocrine system. The final focus of this course is interaction of concepts across the module to gain greater understanding of the complex functioning of higher organisms.

x Module 1: Principles of Cell Function o Introduces cell membrane structure and function, and basic content on cell communication.

x Module 2: Neurons, Synapses and Nervous Systems o Focuses on the details of synaptic transmission, and how signal propagation works in relation to the

neuronal organisation of organisms. x Module 3: Principles of Biochemistry

o Covers basics of biochemistry including types of bonds, properties of water and large biological macromolecules. Also looks into metabolism and cellular respiration.

x Module 4: Skeletons, Skeletal Muscles and Locomotion o Looks at different aspects of locomotion, including skeletal muscle contraction, classifications of

skeletons, and classifications of locomotion. x Module 5: Circulation and Gas Exchange

o Moves from simple comparisons of circulatory systems in different organisms, to a focus on the mammalian respiratory system.

x Module 6: Endocrinology (Semester 1) o Learn basics of endocrine systems, before focussing on the hypothalamus, the pituitary gland, and

adrenaline.


x Good introduction to biology – most of the content at the beginning of each module is revision of senior biology, so students new to biology will not be left behind.

x The practicals are relatively easy to perform well in, especially as tutors are usually willing to discuss what they expect to see in each section.

x It important to understand the basic concepts covered in most of the BIOL1040 modules before progressing to other subjects that will delve into detail on topics like metabolism, the respiratory system and synaptic transmission.


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x PASS sessions for this subject can improve performance in the EOS- PASS tutors are helpful and can give questions similar to EOS questions.

Disadvantages: x The grading matrix prevents a really good score on one assessment item cover for a less impressive score on

another item. Tips:

x Take full advantage of the support available to you; the practical tutors are willing to discuss exactly what they are expecting in your reports. PASS leaders are also quite thorough in the subject matter, and regularly going to these PASS sessions ensures that you are keeping up with the lectures, so that you don’t find that you have several lectures/topics to catch up on during SWOTVAC.

x Don’t underestimate the practical reports, as one low mark can drag down your whole final mark.

Assessment: x Practical Assessment (Final mark calculated as an average of your five individual prac marks)

o There will be five practicals; the first on toad anatomy, the second on osmosis, the third on action potentials and the fourth on skeletal muscle, while the fifth is an ‘integration’ practical. The assessment for the first four practicals is a formal practical report, while the last is assessed via a ‘concept map’ that aims to integrate information from all the systems you have covered.

x Practical Core Competencies o These are four lab techniques that tutors will be assessing over the semester. You must show your

tutor that you are competent at each of these techniques to pass this subject. x Personal Response

o You will be given a selection of biology related radio shows to choose from. Using one as a stimulus, you must write an essay using a personal and reflective writing style, explaining the concepts discussed in the stimulus to a ‘lay audience’.

x eConference/Professional Response o 1. Professional Response- as a group, you must write a 1500 essay, reviewing the current

understanding in the field/biological topic you have selected o 2. Powerpoint Presentation- this powerpoint will complement and summarise the findings you have

described in the professional response o 3. Participation in Biohorizons forum- after reading four other groups professional responses on this

forum, you must ask questions to these groups regarding the findings they have presented o 4. Peer Assessment

x Mastering Biology Quizzes o There will be three of these quizzes during the semester. They will be completed online, through

Mastering Biology, the online resource for the textbook. x EOS

o 80% of exam will be based on the lectures, the remaining 20% will be based on the practicals � 40 multiple choice questions (66 marks, 66 minutes) � 3 short answer questions (24 marks, 24 minutes)

Grading Matrix- To achieve a particular final score, you must achieve a minimum of what is listed in the corresponding column. However, if you fall short of an overall grade in either the practical or communication


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sections, scoring an additional 5% above the required mark in knowledge for all sections that are below the required grade will allow you to move up a grade: eg. if you got Bs in both practical and communication components, by scoring 95% in knowledge (85% + 2 lots of 5% to offset the Bs), a 7 will be awarded.

Final Mark 7 6 5 4 3 2 1 Practical Assessment [average of 4 reports]

A B B C C D E

Practical Core Competencies [4]

Competent Competent Competent Competent Competent Not Competent

Not Competent

Communication [Personal Response & eConference (average of 5 results)]

A B B C C D E

Knowledge [Mastering Biology quizzes (3x5%) + EOS Exam 85%]

85% 75% 65% 50% 47% 35% 0


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STAT1201 Analysis of Scientific Data

Course Information Offered: Semesters 1 & 2 Course Coordinators: Dr Michael Bulmer (Semesters 1 and 2), Dr Melanie Robertson-Dean (Summer Semester) Prerequisites: Year 12 Maths B, or MATH1040 Recommended Prerequisites: None

Course Description This course provides an understanding of the nature of scientific data and the need for statistical analysis. Students are taught to develop statistical expertise, and critical judgement in scientific studies. Students are also given a brief introduction to the importance of ethics in scientific studies. Different types of data, and the best ways to visualise and summarise these types of data are covered.


x The lecturer has been teaching this subject for several years. He tries to make statistics interesting for everyone, and closely follows the textbook (which he himself wrote) so it is easy to catch up on missed lectures.

x The initial basic statistics in this subject will have been encountered in senior maths. x Students are permitted to take an A4 sheet of handwritten notes into the exam, so students can focus on

understanding how to use formulas, rather than memorising all the relevant formulas in the course. As students are also allowed to write full practice questions and answers out on the note sheet, fully completing the practice exam, and making notes from those questions on the note sheet can boost performance in the final exam.

Disadvantages: x The maths involved can be harder than that encountered in grade 12. Students may also find that the basics

are dragged out a lot at the beginning of the semester, and that the harder topics feel relatively rushed at the end.

x Problem solving questions form a large part of the final exam, however, these are not discussed in detail in the lectures – while the techniques used to solve some questions, like distribution questions, are covered in the lectures, the lecturer does not explain many example questions

Tips: x The exam has many ‘application’ questions, so you need to go through practice questions to ensure that you

will be able to answer them. You can find them in the textbook, but additionally you should attend the tutorials, as you get a wider range of questions that your tutors can actually work through with you.

Assessment: x Computer Based Assessment- Quizzes (18%)

o There will be nine of these throughout the semester (one each week), each worth 2% o Each quiz will be based on both the practical for that week, and on lecture content


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x Article Review (14%) o An essay outlining the statistical inferences and ethical issues in a scientific paper of your choice

x Research Proposal (5%) x Experimental Project Report (15%)

o You will write a project report on a study carried out on a ‘virtual human population’, using a focus question of your choice

o Can be completed in a group x EOS (48%)

o There will be a mixture of short answer, short essay and problem solving questions o You are allowed to bring in one A4 sheet of handwritten notes into the exam o 120 mins + 10 mins perusal


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BIOM2011 Integrative Cell and Tissue Biology

Course Information Offered: Semester 1 (open), Semester 2 (restricted to provisional entry MBBS) Course Coordinators: Sem 1: Dr Bradley Launikonis; Sem 2: Dr Bradley Launikonis & Dr Prasad Chunduri Prerequisites: BIOL1020 & BIOL1040 Recommended Prerequisites: None

Course Description Students will develop an understanding of how cells associate & interact to fulfill their normal functions in tissues & organs of the human body. This will include the basic principles of integration & regulation that underpin normal tissue biology.

x Module 1: Muscle Cells o Looks at function and excitation-contraction coupling of the heart, skeletal muscle and smooth

muscle x Module 2: Epithelial Cells

o Covers the structure and function of epithelial cells, including ion movement and protein secretion in specialised types of epithelial cells

x Module 3: Neurons o A detailed look at synaptic transmission, focussing on how different factors (excitatory and inhibitory

potentials) lead to neuromodulation x Module 4: Neuromotor function

o This module covers the relationship between the neuromotor system and the final outcome- movement of the body. Also covered is localisation of function (movement) in the brain

x Module 5: Endocrinology o This module introduces the endocrine system, its components and their functions. Some pathologies

may also be discussed. x Module 6: Immunology

o The module starts by describing the various components of the immune system, looking at innate and adaptive immunity, and concludes by discussing diseases of the immune system


x In modules like the muscle cells and neurons modules, the content picks up from where it was left in first year biology subjects like BIOL1040.

x As lecturers expect students to be able to draw out certain diagrams as answers for short answer questions in the EOS exam, they will clearly explain key points from those diagrams in lectures- some lecturers will even draw out the diagrams (this is especially relevant in the neuromotor module) during the lecture. This means that you will know exactly what to draw in the exam, and will also find it easier to understand the concept underlying that diagram.


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x It important to understand the basic concepts covered in most of the BIOL1040 modules before progressing to other subjects that will delve into detail on topics like metabolism, the respiratory system and synaptic transmission

Disadvantages: x Marking of practicals is significantly harsher than in the first year biology subjects you have taken. This

doesn’t mean good practical marks are impossible; just use the writing skills lectures and support documents on the Blackboard as a guide, and be particularly meticulous in attention to detail, whether this is if a better explanation is needed or if some detail is not required.

x The neuromotor module may be difficult to understand, especially as a summary of the module or aims for that module are not given at the commencement of the module

Tips: x It is possible that you will be studying BIOM2012 in the same semester you take BIOM2011. As BIOM2011 is

a prerequisite of the former, it is a good idea to keep up to date with this subject – understanding certain topics in BIOM2011 will definitely make BIOM2012 easier to understand.

x Practical are worth 40% of this subject, so it is worth discussing the tutors expectations for the reports well in advance. Some tutors will even look at sections of your draft if you are prepared early.

Assessment: x Practical Assessment (40%)

o There will be two practical modules; the lowest scoring practical is worth 15%, and highest scoring practical is worth 25% of final grade

o Each practical module consists of an experimental proposal completed as a group (worth 20% of module mark) and an experimental report completed individually (worth 80% of the module mark)

x EOS (60%) o 40 multiple choice questions o 6 short answer questions o 120 mins o Hurdle – must pass EOS exam to pass subject


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BIOM2012 Systems Physiology

Course Information Offered: Semester 2 Course Coordinators: Dr Stephen Anderson Prerequisites: BIOM2011, BIOL2200 Recommended prerequisite: BIOC2000

Course Description This course explores a variety of physiological systems in depth and builds on knowledge gained in BIOL1040 and BIOM2011. It takes a systemic approach to understanding human physiology and bodily functions. BIOM2012 is composed of 6 topics; Integration and control, homeostatic control of whole organ function, cardiovascular function, respiration, endocrine regulation of metabolism and neurophysiology. These are organised in a manner which focuses on response to change, homeostasis and altered function in various pathological conditions.

x Module 1: Homeostatic control of whole organ function o Looks at various organs in the human body from a normal physiological perspective and their

respective functions x Module 2: Endocrine: Glucose homeostasis

o Using concepts of homeostasis learned previously this module delves into energy homeostasis and management

x Module 3: Cardiovascular Function o Introduces concepts such as blood pressure and heart rate maintenance and how the

cardiovascular system copes with an ever changing workload. x Module 4: Respiration

o Similarly to the cardiovascular module, this module focuses on the respiratory system and its control

x Module 5: Endocrine: regulation of metabolism o This module is related to the glucose homeostasis module and draws on similar concepts however

with more of a whole systems point of view x Module 6: Neurophysiology

o This module looks at neuronal involvement in homeostasis, balance etc. It involves a fair bit of understanding and learning of pathways and processes.


x This course is the excellent to gain perspective on bodily function and to get a very detailed understanding of systemic function in the human body.

x It is not an introductory course and most definitely builds on previous knowledge; it is a great way to tie in cell and molecular physiological concepts learned in previous courses.

x It would be a great way to cement the basics of human physiology and function prior to entering medicine.


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Disadvantages: x It is expected that the vast majority students who undertake this course already have a basic understanding

of cell and molecular physiology by completing BIOM2011 and BIOL2200. If undertaken in your second semester in first year, you will not meet the prerequisites which may make some of the concept difficult to understand, although this is easily overcome with a bit of study.

x Although premedical students can complete the subject without undertaking the prerequisites it is highly recommended that at the least BIOL1040 is undertaken prior to commencing, and that BIOM2011 is undertaken simultaneously with BIOM2012.

Tips: x Always keep on top of the lectures and concepts do not let yourself get lost; it is easy to lose yourself in the

course material and get confused. If this happens, try getting a big picture view and moving in to the specifics.

x During your lab sessions, make sure you talk to your tutor and ask for constant feedback on your work; they will be only too happy to help you out. Try to get a broad understanding of all the concepts and how everything fits in the big picture.

x Finally, do not try to cram at the last minute; this is not one of those subjects.

Assessment x Laboratory report (20%)

o 1500 word report on the experiments conducted in the practicals x Presentation Slides (10%)

o Slides used in your presentation of the hypothesis & aims, design, methods and expected outcomes of your groups experiment. This is the pre-experiment proposal.

x Draft Hypothesis (5%) o Part of the proposal presentation

x Oral presentation (5%) o Part of the proposal presentation

x End of semester exam (60%) � 10 minutes perusal � 120 minutes working time � Multiple choice and Short answer questions


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BIOL2200: Cell Structure & Function

Course Information Offered: Semester 1 Course Coordinators: Dr Stuart Kellie Prerequisites: BIOL1020 Recommended prerequisite: BIOL1040

Course Description This course is intended to be a comprehensive introduction to Cell Biology. You discuss the vast diversity of cells and how their structures subserve their functions. Specifically, you will cover cell division, the composition and function of membranes and organelles, the cytoskeleton and trafficking of cargo around the cell, and the way that signals are carried both within and beyond cells. The pracs will focus on microscopy, bench techniques, and computer techniques. In the first practical session you assess specimen slides using a computer tool and in the second you genetically engineer yeast. The unit is split into six modules.

x The Cell Cycle o Covers different factors involved in controlling the cell cycle, such as phosphorylation and

ubiquitination. A clinical perspective is provided at the end of the module, with topics like cancer and the properties of cancer cells

x Biochemistry o A short module that contains a lot of revision. In the past two years the module has not been

completed. x Organelles

o Overs the properties of all the major organelles in the cell, such as the ER, golgi, nucleus and mitochondria

x The Cytoskeleton o Covers microtubules, microfilaments, intermediate filaments, and cellular adhesion. Is very useful

knowledge for the prac report. x Signal Transduction.

o A summary of several signalling mechanisms, including topics like GPCR Pathways, receptor tyrosine kinase pathways , cytokine receptors pathways and nuclear receptors

x Cell Transport o This could easily be a confusing module however it is very engaging and interesting. The exam for

this component has not been difficult in the past. However be sure to know the details of clathrin-mediated endocytosis and the differential outcomes of signaling cascades.


x This course is one of the best you will do in a biological science major – it may not seem like it at the time but in hindsight it is. It steps you through things slowly, and the lab reports are relatively simple.


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x Module 1 and 5 are very interesting, and throughout the whole course the lecturers link everything back to human health very well.

Disadvantages: x You may find that some modules are more tedious than others, such as Module 2, making study for that

module more difficult to get into. x There is a large range of topics covered within this subject, and as your approach the end of the course, the

modules will only make sense if you properly understand earlier modules. This can be overwhelming if not approached with regular study.

Tips: x The EOS exam is quite easy overall, but there is a disproportional amount of questions from module 2 (so

make sure you study it, as most people in my cohort avoided it due to it being the most tedious module). x The literature review is easy if you pick a simple article – word of advice: the shortest article is the hardest.

Assessment x Lab 1 Group Poster Presentation (10%)

o Scientific figure and presentation to a group, based on data obtained during practical classes (cardiac myocytes)

o Completed in groups of 2 students x Lab 2 Individual Report (10%)

o Practical report based on yeast cell analysis in practicals o Practicals are carried out in groups of 2 but the reports are individual work

x Literature Summary (20%) o One page summary and analysis of a journal article of the students’ choice.

x End of semester exam (40%) � 10 minutes perusal � 90 minutes working time � Multiple choice and Short answer questions


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BIOM2402 Principles of Pharmacology

Course Information Offered: Semester 2 Course Coordinators: Dr Mary-Louise Manchadi & Dr Simon Phipps Prerequisites: BIOL2200 + CHEM1020 Recommended Prerequisites: BIOC2000

Course Description This course introduces students to fundamental concepts in drug action and drug disposition. The binding of drugs to receptors, receptor activation and inhibition, effect of drugs on cell signalling, drug absorption and metabolism, genetic determinants of drug action and drug toxicity are topics covered within the modules of this course. Students are also introduced to experimental approaches to study drug effects.

x Introduction to Pharmacology (Dr Matthew Cheesman) o Looks at quantitative drug effects, and drug receptors at the beginning of the semester, before a few

lectures on isolated topics like mechanisms of childbirth drugs, oestrogens and progesterones towards the end of semester

x Drug Disposition (Dr Neville Butcher) o Focuses on drug disposition, and the different methods of drug administration.

x Pharmacogenetics (Dr Neville Butcher) o Explains how genetic variations between individuals can alter the effects of drugs in individuals

x Mediators of the Autonomic Nervous System (Dr Karin Borges) o Covers pharmacology topics briefly in the autonomic nervous system, the GI system and the

endocrine system x Circulatory System (Dr Tamara Paravicini)

o Focus on the drugs working on the cardiorespiratory system and their means of action x Asthma (Dr Simon Phipps)

o Brief module on drugs used to treat respiratory difficulty (asthma) x Mediators of the Central Nervous System (Dr Mary-Louise Manchadi)

o Looks at pharmacology involved in the central nervous system, including the actions of specific classes of drugs like dopamine, opioids and local anaesthetics

x Epilepsy (Dr Karin Borges) x Endocrine Pharmacology (Dr Karin Borges) x Pharmacology of Childbirth and Female Reproduction (Dr Matthew Cheesman)


x Many of the drug names are familiar, and learning their mechanisms within the body is interesting – it is easy to stay engaged with lectures throughout the semester

x While the basic mechanisms behind the actions of some drugs and systems is required, the concepts in this subject are not overly challenging to understand


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x The practicals are relevant to what is learnt in lectures (particularly the first few lectures under Dr Matthew Cheesman) and aid in understanding those concepts (agonists, partial agonists, antagonists, receptor classification etc)

x Skills learnt in the practical sessions, such as setting up and using an organ bath will be useful in future endeavours in the laboratory, especially for other pharmacology subjects in following semesters.

Disadvantages: x Note that due to the way the biomedical major of BSc has been adapted for BSc/MBBS students, it is likely

that if BIOM2402 is taken in the first year, BIOL2200 (a prerequisite) and BIOC2000 (a recommended prerequisite) will not have been taken yet. This is not a great disadvantage as all concepts in BIOM2402 are explained from the basics; however, you may have to put in extra work in some areas that are not explained in depth as they are assumed knowledge.

x Despite not falling in the prerequisites list, an understanding of concepts from BIOM2011 and BIOM2012 will help immensely as the mechanisms by which drugs affect systems in the body is often covered in the corresponding modules of these subjects.

x There is a large amount of memorising of drug classifications involved – this cannot be avoided x The multiple choice questions on the mid semester and EOS exam can be challenging, as many of them

require you to know the specific function or mechanism of one particular drug. x There are a large range of topics covered within this subject, with little association between modules, and

sometimes even between adjacent lectures in a module. This can be overwhelming if not approached with regular study.

Tips: x From the beginning of semester, try to keep track of prominent drug names that your lecturers seem to

emphasise or continually talk about. x It will be difficult at the end of semester to trawl through all of your lecture notes to make that list of drug

names that need to be memorised for the final exam – try to keep a list as you go through the subject

Assessment: x Laboratory Report (25%)

o After a series of Computer Assisted Learning (CAL) and wet lab sessions, a lab report on the organ bath experiments carried out must be submitted

x Midsemester Exam (20%) o Only multiple choice questions- based on the first two ‘modules’- lectures by Dr Cheeseman and Dr

Butcher x Virtual Lab Practical Class (5%)

o Participating in this online ‘practical class’ involving similar methods to the regular practical sessions is worth 5% of the final mark for this subject

x EOS (50%) o 40 multiple choice questions (1.5 marks each) o 5 short answer questions (12 marks each) o 120 mins + 10 mins perusal


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MICR2000: Microbiology and Immunology

Course Information Offered: Semester 2 Course Coordinators: Associate Professor Roy Hall Prerequisites: BIOL1020 Recommended Prerequisites: BIOC2000

Course Description This course explores the diversity of microorganisms, their cellular biology, growth & nutrition, metabolism, & basic genetics. The role of microorganism in disease, as well as their ecology & applications in biotechnology is also examined. Students will gain an insight into the immune response to infection by studying the innate, humoral & cellular immune systems & their functions in health & disease. The practical component of the course will include laboratory experiments to demonstrate principles learned in the lectures, where students will gain practical skills in safely handling microbial cultures for isolation & identification. The course provides the fundamental knowledge & skills needed to proceed further in microbiology, but also for all courses or disciplines involving molecular biology & biotechnology.

x Module 1: Introduction to Microorganisms o Introduces microbial cell structures and how these correlate with function

x Module 2: Environmental Microbiology o Looks through different environments in which microorganisms are found and the mechanisms they

use to survive in such environments x Module 3: Bacteriology

o Goes into more detail about bacterial structures and genes and how these relate to function, as well as their uses in biotechnology

x Module 4: Eukaryotic Microbes o Focusses on fungi in particular, including an introduction to fungi, use of fungi in biotechnology and

industry, as well as fungal pathogens and diseases. x Module 5: Virology

o Looks at the structures present within viruses, mechanisms involved in viral replication, viral diseases and current research in biotechnology of viruses.

x Module 6: Immunology and Host-Pathogen Interactions o An introduction to immunology, focusing on the cellular and chemical mediators of both innate and

acquired immunity, as well as a brief look at the key immunological issues in medicine.


x Overall, MICR2000 is not a difficult course in that it does not require an understanding of complex concepts x The two practical reports are relatively easy to do well in x The EOS is relatively easy


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x Taking this course in conjunction with BIOM2011 provides a direct overlap of content (with very minor differences in specific details that are required) in their respective final modules, reducing your workload for both courses

x A knowledge of microbiology and immunology is required in some areas of the medical course x Processes more relevant to laboratory based biomedical and biological science topics learnt in practical

sessions are in more detail than in previous courses, as well as the appropriate context for these processes, and are particularly useful to have if undertaking any form of research (e.g. pipetting, vortexing, centrifugation, assays/immunoassays)

Disadvantages: x The mid-semester quizzes are both disproportionately hard compared to the EOS and require a lot of rote

learning that is difficult to cram; this is a stumbling block for many x The rote nature of the course can make study very tedious; more so than in other courses

Tips: x Essentially, MICR2000 will feel like BIOL1020 on steroids if taken immediately after it. It is very easy to let

revising content for this course pile up into overwhelming amounts before the mid-semester quizzes, as the content can be quite dry because of the amount of rote learning involved. Especially prior to the mid-semester quizzes, it is very important to be up-to-date with lecture content, and not become discouraged or disillusioned doing so. Many did not do as well as they could have in MICR2000 because of this, given the relative ease of the other assessment tasks.

x Attention to detail is important for the practical reports

Assessment: x Practical pre-tests (2.5%)

o Each practical sessions will typically contain multiple experiments which are often undertaken across a number of weeks, e.g. for one week, experiments 4, 5A and 7C are completed; the following week, experiments 5B, 6 and 7D are completed

o For each prac, 5 questions are asked about details relating to experiments to be undertaken for the day’s session. These typically involve knowing specific details in the recognition of different outcomes in each experiment, or of the importance of particular steps in the method

x Upkeep of practical notebook (2.5%) o Involves generating a low detail practical write-up – i.e. aim, method, results, discussion etc o The amount of detail required for this can vary from tutor to tutor

x Mid Semester Quiz 1 (15%) o Tests modules 1 and 2 and relevant completed practicals

� 10 multiple choice questions (1 mark each) � 5 short answer questions (total 4 marks) � 30 minutes

x Mid Semester Quiz 2 (15%) o Tests modules 3 and 4 and relevant completed practicals

� 10 multiple choice questions (1 mark each) � 5 short answer questions (total 4 marks) � 30 minutes

x Practical Report 1 (10%)


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o Takes one experiment that has been followed through to completion that allows for quantitative analysis from the practicals, and generating a full write-up of approximately 800 words; no referencing required

x Practical Report 2 (10%) o As above

x EOS (45%) o All modules covered, with a greater emphasis on modules 5 and 6

� 30 multiple choice questions (2 marks each) � 10 short answer questions (2 marks each) – can be broken into sub-questions � 5 short answer questions (4 marks each) – can be broken into sub-questions � 120 minutes

Documents

STUDY GUIDE - UQPMS – UQ Premedical · PDF fileBIOL1040 Cells to Organisms