Study Control

BRAIN INFLAMMATION

WB INFLAMMATION

1- Preparation of [18F]FDG2- PET study

1- Preparation of [11C]PK111952- PET study

N

NCH3

11

O

Cl

O

OH

HH

H

OH

OH

H F18

H

OH

PHARMACODYNAMIC STUDIES

2

Workpackage 1

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Characterization ofmetal oxide NPs in Biologically relevant conditions and catalytic activity

R_Zn Ox+Meth blue+UV

0

0,5

1

1,5

2

2,5

3

3,5

4

4,5

5

200 300 400 500 600 700 800

long onda

Ab

s

T0

T 15min

T 30min

UV spectra of methylene blue in presence of ZnO nanoparticles ( 1 mg/ml) after being irradiated with UV light for different times

DLS of TiOx nanoparticles in water, NaCl, PBSand cell media

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Synthesis of radiolabelled NPs for Positron Emission tomography

R- detector

Pharmacokinetics studies