Page ?Page ?Name: __________________________ Date:
_____________1.Which of the following statements about metabolism
is correct?A)anabolism is all metabolic reactions in which small
biochemical molecules are joined together to form larger
onesB)catabolic reaction sequences usually consume
energyC)anabolism is the sum total of all chemical reactions that
take place within a cellD)the reactions involved in the oxidation
of glucose are anabolic2.Which of the following statements about
mitochondria is correct?A)the inner membrane of mitochondria is
predominantly composed of lipidsB)the space between the inner and
outer mitochondrial membrane is called the matrixC)the folds of the
outer membrane are called cristaeD)mitochondria contain an outer
membrane and a multifolded inner membrane3.Which of the following
diagrams gives the correct identities and arrangement of the
structural subunits in coenzyme A?A)AB)BC)CD)D4.The missing
structural subunit in the following diagram for flavin adenine
dinucleotide isA)phosphate.B)ribose.C)ribitol.D)deoxyribose.5.The
correct notation for the reduced form of nicotinamide adenine
dinucleotide isA)NAD+.B)NAD.C)NADH.D)NADH2.6.Which of the following
is a correct skeletal equation for a hydrolysis reaction involving
adenosine phosphates?A)ATP ADP + 2PiB)ADP AMP + 2PiC)ATP AMP +
PPiD)ATP ADP + PPi7.The active portion of coenzyme A is
theA)sulfhydryl group of 2-aminoethanethiol.B)B vitamin pantothenic
acid.C)phosphate group on carbon 3' of ribose.D)amino group of
2-aminoethanethiol.8.The fuel for the citric acid cycle isA)acetyl
CoA.B)citric acid.C)citrate ion.D)oxaloacetate ion.9.Which of the
following is a correct general description of the reaction that
occurs in the first step of the citric acid cycle?A)C2 + C4 C6B)C3
+ C3 C6C)C2 + C2 + C2 C6D)C4 + C4 C6 + C210.In which two steps of
the citric acid cycle are molecules of carbon dioxide
produced?A)steps 2 and 5B)steps 3 and 5C)steps 3 and 4D)steps 4 and
611.How many NADH and FADH2 molecules are produced, respectively,
during one turn of the citric acid cycle?A)2, 2B)3, 1C)1, 3D)2,
312.Which of the following citric acid intermediates is not a C4
species?A)malateB)oxaloacetateC)isocitrateD)succinyl CoA13.In which
of the following listings of citric acid cycle intermediates are
the compounds listed in order in which they are encountered in a
turn of the cycle?A)citrate, malate,
succinateB)alpha-ketoglutarate, succinate, malateC)succinyl CoA,
malate, isocitrateD)oxaloacetate, fumarate, isocitrate14.At which
step in the electron transport chain does O2 participate?A)first
stepB)second stepC)next to last stepD)last step15.The number of
membrane-bound protein complexes associated with the electron
transport chain isA)one.B)two.C)three.D)four.16.Which of the
following electron carriers is not part of a membrane-bound protein
complex in the electron transport chain?A)FeSPB)CoQC)cyt c1D)cyt
a317.Which of the following sets of electron carriers is associated
with the electron transport chain reactions that occur at protein
complex I?A)CoQ, FeSP, cyt b, cyt cB)NADH, FMN, FeSP, CoQC)cyt c,
cyt a, cyt a3D)FADH2, FeSP, CoQ18.ATP synthesis via oxidative
phosphorylation depends on the passage of which of the following
species through membrane-bound ATP
synthase?A)NADHB)FADH2C)H+D)NAD+19.How many moles of ATP result
from the entry of 5 moles of FADH2 into the electron transport
chain?A)5B)7.5C)10D)12.520.How many ATP molecules result from the
"processing" of 10 acetyl CoA molecule through the common metabolic
pathway?A)20B)80C)100D)24021.In a mitochondrion theA)inner membrane
separates the matrix from the intermembrane space.B)the inner
membrane is more permeable than the outer membrane.C)ATP-synthase
complexes are found on the folds of the outer membrane.D)more than
one correct responseE)no correct response22.Which of the following
substances does not contain a B vitamin as a structural
subunit?A)flavin adenine dinucleotideB)nicotinamide adenine
dinucleotideC)coenzyme AD)more than one correct responseE)no
correct response23.Which of the following substances has two
unsubstituted ribose molecules as structural
subunits?A)FADH2B)NAD+C)CoAD)more than one correct responseE)no
correct response24.Which of the following substances contains two
or more high energy phosphate bonds?A)ATPB)ADPC)AMPD)more than one
correct responseE)no correct response25.Which of the following is a
correct letter designation for the reduced form of a
coenzyme?A)NAD+B)FADH2C)NADH2D)more than one correct responseE)no
correct response26.Which of the following are products of the
citric acid cycle?A)acetyl CoA and NAD+B)acetyl CoA and CO2C)CO2
and H2OD)more than one correct responseE)no correct
response27.Which of the following citric acid cycle intermediates
is decarboxylated during the operation of the
cycle?A)oxaloacetateB)isocitrateC)succinateD)more than one correct
responseE)no correct response28.Which of the following citric acid
cycle intermediates is a C4
species?A)fumarateB)citrateC)malateD)more than one correct
responseE)no correct response29.In which of the following citric
acid cycle reactions does the coenzyme FAD participate?A)citrate
isocitrateB)succinate fumarateC)malate oxaloacetateD)more than one
correct responseE)no correct response30.Which of the following
statements concerning citric acid cycle reactions is correct?A)Two
secondary alcohol oxidations occur.B)Water adds to a carbon-carbon
double bond once.C)Two phosphorylation reactions occur.D)more than
one correct responseE)no correct response31.Which of the following
carry electrons from the citric acid cycle to the electron carriers
of the electron transport chain?A)CoAB)NAD+C)FADH2D)more than one
correct responseE)no correct response32.Which of the following
carriers transports electrons from protein complex I to protein
complex III during operation of the electron transport chain?A)cyt
a3B)cyt c1C)FMND)more than one correct responseE)no correct
response33.Which of the following substances is both a reactant and
a product in the operation of the electron transport
chain?A)O2B)FADH2C)CoQD)more than one correct responseE)no correct
response34.At which protein complex site in the electron transport
chain does proton pumping occur?A)protein complex IB)protein
complex IIC)protein complex IIID)more than one correct responseE)no
correct response35.Oxidative phosphorylation is the process in
which ATP is synthesizedA)from ATP synthase.B)from ADP.C)using
energy from the dissipation of a proton gradient.D)more than one
correct responseE)no correct responseUse the following to answer
questions 36-45:In each of the following multiple-choice questions
characterize EACH of the three given statements as being TRUE or
FALSE and then indicate the collective true-false status of the
statements using the choices a) All three statements are true.b)
Two of the three statements are true.c) Only one of the statements
is true.d) None of the statements is true.36.Statements: (1) In the
last step of the ETC, molecular oxygen is converted to water.(2)
The B vitamin portion of the structure of coenzyme A, which
involves riboflavin, is the reactive site in the molecule.(3) All
of the reactions of the CAC take place in the mitochondrial
matrix.A)All three statements are true.B)Two of the three
statements are true.C)Only one of the statements is true.D)None of
the statements is true.37.Statements: (1) FADH2 is the oxidized
form of the coenzyme flavin adenine dinucleotide.(2) All of the
electron carriers of the ETC contain iron, and one of them also
contains copper.(3) One turn of the CAC generates two CO2
molecules, two NADH molecules and two FAD2 molecules.A)All three
statements are true.B)Two of the three statements are true.C)Only
one of the statements is true.D)None of the statements is
true.38.Statements: (1) Both ribosomes and mitochondria are
examples of organelles.(2) Cytochromes are heme-containing proteins
that can undergo reversible oxidation and reduction.(3) The
electrons that pass through the various steps of the ETC lose some
energy with each transfer along the chain.A)All three statements
are true.B)Two of the three statements are true.C)Only one of the
statements is true.D)None of the statements is true.39.Statements:
(1) In the first step of the CAC, a C2 molecule and a C4 molecule
combine to produce a C6 molecule.(2) ATP, ADP, and AMP differ from
each other in the number of adenine subunits present.(3) The
process by which ATP is produced during the operation of the ETC is
called oxidative phosphorylation.A)All three statements are
true.B)Two of the three statements are true.C)Only one of the
statements is true.D)None of the statements is true.40.Statements:
(1) High-energy phosphate compounds contain one or more strained
bonds which release above-average amounts of energy when broken.(2)
In the ETC, NADH is oxidized to NAD+.(3) The fuel for the CAC is
acetyl CoA.A)All three statements are true.B)Two of the three
statements are true.C)Only one of the statements is true.D)None of
the statements is true.41.Statements: (1) The CO2 molecules
produced in the citric acid cycle are the CO2 molecules we exhale
in the process of respiration.(2) The oxidized form of nicotinamide
adenine dinucleotide is NAD+ and the reduced form in NADH2.(3)
During ETC operation, a buildup of protons occurs on the matrix
side of the inner mitochondrial membrane.A)All three statements are
true.B)Two of the three statements are true.C)Only one of the
statements is true.D)None of the statements is true.42.Statements:
(1) Two ribose subunits are present in the coenzyme flavin adenine
dinucleotide.(2) In the common metabolic pathway, 10 molecules of
ATP are produced per acetyl CoA catabolized.(3) The purpose of step
2 in the CAC is to convert a secondary alcohol to a tertiary
alcohol.A)All three statements are true.B)Two of the three
statements are true.C)Only one of the statements is true.D)None of
the statements is true.43.Statements: (1) Some, but not all,
protein complex sites associated with the ETC serve as proton
pumps.(2) The rate at which the CAC operates is controlled by the
body's need for ATP.(3) Anabolic reactions usually require energy
input in order to proceed.A)All three statements are true.B)Two of
the three statements are true.C)Only one of the statements is
true.D)None of the statements is true.44.Statements: (1)
Mitochondria contain a multifolded outer membrane and an inner
membrane(2) Two of the electron carriers of the ETC transport
change are mobile, moving between protein complex sites.(3) The
NADH and FAD2 formed during the CAC carry electrons and H+ ions to
the ETC.A)All three statements are true.B)Two of the three
statements are true.C)Only one of the statements is true.D)None of
the statements is true.45.Statements: (1) Inhibition of the ETC is
the mechanism by which cyanide exerts its deadly effect.(2) Brown
fat cells contain the uncoupling agent thermogenin, a protein that
creates a proton channel through the outer mitochondrial
membrane.(3) One of the body's mechanisms for adaptation to cold is
the production of brown fat tissue.A)All three statements are
true.B)Two of the three statements are true.C)Only one of the
statements is true.D)None of the statements is true.Use the
following to answer questions 46-50:For each of the molecular
structural characteristics, select the correct molecule from the
response list. Responses may be used more than once or need not be
used at all.a)ATPb)CoAc)FADd)NAD+46.Contains a pantothenic acid
subunit47.Contains a phosphorylated ribose subunit48.Does not
contain a B vitamin as part of its structure49.Reactive site in the
molecule is a SH group50.Contains a ribitol subunitUse the
following to answer questions 51-55:For each of the citric acid
cycle reactions, select the type of molecules involved (in terms of
number of carbon atoms present) using the response list. Responses
may be used more than once or need not be used at all.a)C6 C6b)C6
C5c)C5 C4d)C4 C451.Citrate isocitrate52.Succinate
fumarate53.Isocitrate -ketoglutarate54.Malate
oxaloacetate55.Fumarate malateUse the following to answer questions
56-60:Characterize each of the citric acid cycle reactions as to
type of reaction using the response list. Responses may be used
more than once or need not be used at all.a)oxidation of a 2
alcoholb)oxidation with FAD as the oxidizing agentc)hydration
reactiond)hydrolysis reaction56.Isocitrate
-ketoglutarate57.Succinate fumarate58.Succinyl CoA
succinate59.Malate oxaloacetate60.Fumarate malateUse the following
to answer questions 61-65:For each of the ETC electron carrier
characterizations, select the electron carrier's name using the
response list. Responses may be used more than once or need not be
used at all.a)CoQb)cyt a3c)FMNd)FeSP61.Interacts with molecular
O262.Interacts with NADH63.Interacts with FADH264.Contains Fe and
Cu65.Contains Fe but not CuUse the following to answer questions
66-70:For each of the ETC electron carriers, select the number of
ETC protein complexes with which it is associated using the
response list. Responses may be used more than once or need not be
used at all.a)one protein complexb)two protein complexesc)three
protein complexesd)four protein
complexes66.FADH267.NADH68.CoQ69.cyt c70.cyt bAnswer
Key1.A2.D3.C4.C5.C6.C7.A8.A9.A10.C11.B12.C13.B14.D15.C16.B17.B18.C19.B20.C21.A22.E23.B24.A25.B26.E27.B28.D29.B30.D31.C32.E33.C34.D35.D36.C37.D38.A39.B40.A41.C42.C43.A44.B45.B46.b47.b48.a49.b50.c51.a52.d53.b54.d55.d56.a57.b58.d59.a60.c61.b62.c63.d64.b65.d66.a67.a68.c69.b70.a
