Stickler Disease: Eye

Michael Shapiro, MD

Retina Consultants, LTD

Chicago

In Memory of

Gunnar Stickler

1925-2010

Stickler Syndrome

Michael Shapiro, MD

Associate Professor of Ophthalmology

Retina Surgeon

UIC Eye Center

The Eye

• Focuses an image of the world on the retina.

• Retina translates into nerve impulses and send to the brain.

Basic Anatomy

Camera Analogy

Eye Disease

• Early Myopia • Vitreous anomaly • Retinal Detachment• Retinal Degeneration

– Radial Perivascular– Posterior chorioretinal atrophy

• Early onset Cataract • Glaucoma

Stickler GB, Hughes W, Houchin P. Clinical features of hereditary progressive arthro-ophthalmopathy (Sticklersyndrome): a survey. Genet Med. 2001 May-Jun;3(3):192-6.

Prevalence of Eye Disease by Age

Stickler GB, Hughes W, Houchin P. Clinical features of hereditary progressive arthro-ophthalmopathy (Sticklersyndrome): a survey. Genet Med. 2001 May-Jun;3(3):192-6.

Prevalence of Retina Detachment by AgeRetina Detachment

0

10

20

30

40

50

60

70

0 9 19 29 39 49 59 79

Age (yrs)

Pre

va

len

ce

(%

)

Treatments for Retinal Detachment

Stickler GB, Hughes W, Houchin P. Clinical features of hereditary progressive arthro-ophthalmopathy (Sticklersyndrome): a survey. Genet Med. 2001 May-Jun;3(3):192-6.