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Stent-assisted Mechanical Recanalization for Treatment of Acute Intracerebral Artery Occlusion C. Roth , P. Papanagiotou , S. Walter @ , S.Behnke @ , C. Becker @ , W. Reith Department of Diagnostic and Interventional Neuroradiology Department of Neurology @ Saarland University Hospital, Homburg, Germany

Stent-assisted Mechanical Recanalization for Treatment of Acute Intracerebral Artery Occlusion

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Stent-assisted Mechanical Recanalization for Treatment of Acute Intracerebral Artery Occlusion. C. Roth ‡ , P. Papanagiotou ‡ , S. Wal ter @ , S.Behnke @ , C. Becker @ , W. Reith ‡. Department of Diagnostic and Inte rventio nal Neuroradiology ‡ Department of Ne urolog y @ - PowerPoint PPT Presentation

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Page 1: Stent-assisted Mechanical Recanalization for Treatment of Acute Intracerebral Artery Occlusion

Stent-assisted Mechanical Recanalization for Treatment of

Acute Intracerebral Artery Occlusion

C. Roth‡, P. Papanagiotou‡, S. Walter@, S.Behnke@, C. Becker@, W. Reith‡

Department of Diagnostic and Interventional Neuroradiology‡

Department of Neurology@

Saarland University Hospital, Homburg, Germany

Page 2: Stent-assisted Mechanical Recanalization for Treatment of Acute Intracerebral Artery Occlusion

Recanalizationrate mRS 0-2 ICH

69.5% 36% 9.8%

72.4% 37.9%

5%45% (mRS 0-1)100%

7%

81.6% 25% 11.2%

Page 3: Stent-assisted Mechanical Recanalization for Treatment of Acute Intracerebral Artery Occlusion

Stenting in acute stroke

Prompt flow-restorationHigh recanalization rateFast recanalization

Aggressive anticoagulationThrombus is only pressed against the wallIn-Stent stenosis possible

Advantages Disadvantages

Page 4: Stent-assisted Mechanical Recanalization for Treatment of Acute Intracerebral Artery Occlusion
Page 5: Stent-assisted Mechanical Recanalization for Treatment of Acute Intracerebral Artery Occlusion
Page 6: Stent-assisted Mechanical Recanalization for Treatment of Acute Intracerebral Artery Occlusion

22 patientsOctober 2009- May 2010

Nov 2010

Page 7: Stent-assisted Mechanical Recanalization for Treatment of Acute Intracerebral Artery Occlusion

Patients

13/22 patients iv lysis10/22 patients ia lysisSolitaire AB/FR

Page 8: Stent-assisted Mechanical Recanalization for Treatment of Acute Intracerebral Artery Occlusion

Zur Anzeige wird der QuickTime™ Dekompressor „“

benötigt.

Page 9: Stent-assisted Mechanical Recanalization for Treatment of Acute Intracerebral Artery Occlusion

angiographical outcomeTICI 2b or 3 in 20/22 patients 90.9%

Number of device runs 1.74(1-4)Vasospasm 3/22 (13.6%)

Stent-assisted Mechanical Recanalization for Treatment of Acute Intracerebral Artery OcclusionRoth C, Papanagiotou P, Reith W et al.Stroke, in press

Page 10: Stent-assisted Mechanical Recanalization for Treatment of Acute Intracerebral Artery Occlusion

clinical outcome

symptomatic ICH: 2/22 (9%)

Stent-assisted Mechanical Recanalization for Treatment of Acute Intracerebral Artery OcclusionRoth C, Papanagiotou P, Reith W et al.Stroke, in press

Page 11: Stent-assisted Mechanical Recanalization for Treatment of Acute Intracerebral Artery Occlusion

Zur Anzeige wird der QuickTime™ Dekompressor „H.264“

benötigt.

12:5812:58M1 occlusion

Page 12: Stent-assisted Mechanical Recanalization for Treatment of Acute Intracerebral Artery Occlusion

Zur Anzeige wird der QuickTime™ Dekompressor „H.264“

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13:0613:06Placement of the Solitaire device

Page 13: Stent-assisted Mechanical Recanalization for Treatment of Acute Intracerebral Artery Occlusion

Zur Anzeige wird der QuickTime™ Dekompressor „H.264“

benötigt.

13:0613:06Prompt flow restoration

Page 14: Stent-assisted Mechanical Recanalization for Treatment of Acute Intracerebral Artery Occlusion

Zur Anzeige wird der QuickTime™ Dekompressor „H.264“

benötigt.

13:0813:08Thrombus in stent mesh

Page 15: Stent-assisted Mechanical Recanalization for Treatment of Acute Intracerebral Artery Occlusion

Zur Anzeige wird der QuickTime™ Dekompressor „H.264“

benötigt.

Thrombus from aspiration syringe

Page 16: Stent-assisted Mechanical Recanalization for Treatment of Acute Intracerebral Artery Occlusion

Zur Anzeige wird der QuickTime™ Dekompressor „H.264“

benötigt.

13:1013:10Angiographical outcome

Page 17: Stent-assisted Mechanical Recanalization for Treatment of Acute Intracerebral Artery Occlusion

Aspirated thrombus & thrombus in device mesh

20/2290.9%

Stent-assisted Mechanical Recanalization for Treatment of Acute Intracerebral Artery OcclusionRoth C, Papanagiotou P, Reith W et al.Stroke, in press

Page 18: Stent-assisted Mechanical Recanalization for Treatment of Acute Intracerebral Artery Occlusion

recanalization mRS 0-2 ICH

69.5% 36% 9.8%

72.4% 37.9% 7%

81.6% 25% 11.2%

5%45% (mRS 0-1)100%

90.9% 50% 9%Nov 2010

Page 19: Stent-assisted Mechanical Recanalization for Treatment of Acute Intracerebral Artery Occlusion

Mechanical REcanalization with FLOW

Restoration in Acute Ischemic Stroke ReFlow Study

•Monocentric Prospective Trial •40 Patients•Primary endpoint: favourable clinical

outcome at 30 and 90 days (mRS 0 to2)•Solitaire FR Recanalization DeviceSaarland University Hospital, Homburg, Germany

[email protected]

Page 20: Stent-assisted Mechanical Recanalization for Treatment of Acute Intracerebral Artery Occlusion