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Stent-assisted Mechanical Recanalization for Treatment of Acute Intracerebral Artery Occlusion. C. Roth ‡ , P. Papanagiotou ‡ , S. Wal ter @ , S.Behnke @ , C. Becker @ , W. Reith ‡. Department of Diagnostic and Inte rventio nal Neuroradiology ‡ Department of Ne urolog y @ - PowerPoint PPT Presentation
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Stent-assisted Mechanical Recanalization for Treatment of
Acute Intracerebral Artery Occlusion
C. Roth‡, P. Papanagiotou‡, S. Walter@, S.Behnke@, C. Becker@, W. Reith‡
Department of Diagnostic and Interventional Neuroradiology‡
Department of Neurology@
Saarland University Hospital, Homburg, Germany
Recanalizationrate mRS 0-2 ICH
69.5% 36% 9.8%
72.4% 37.9%
5%45% (mRS 0-1)100%
7%
81.6% 25% 11.2%
Stenting in acute stroke
Prompt flow-restorationHigh recanalization rateFast recanalization
Aggressive anticoagulationThrombus is only pressed against the wallIn-Stent stenosis possible
Advantages Disadvantages
22 patientsOctober 2009- May 2010
Nov 2010
Patients
13/22 patients iv lysis10/22 patients ia lysisSolitaire AB/FR
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angiographical outcomeTICI 2b or 3 in 20/22 patients 90.9%
Number of device runs 1.74(1-4)Vasospasm 3/22 (13.6%)
Stent-assisted Mechanical Recanalization for Treatment of Acute Intracerebral Artery OcclusionRoth C, Papanagiotou P, Reith W et al.Stroke, in press
clinical outcome
symptomatic ICH: 2/22 (9%)
Stent-assisted Mechanical Recanalization for Treatment of Acute Intracerebral Artery OcclusionRoth C, Papanagiotou P, Reith W et al.Stroke, in press
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12:5812:58M1 occlusion
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13:0613:06Placement of the Solitaire device
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13:0613:06Prompt flow restoration
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13:0813:08Thrombus in stent mesh
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Thrombus from aspiration syringe
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13:1013:10Angiographical outcome
Aspirated thrombus & thrombus in device mesh
20/2290.9%
Stent-assisted Mechanical Recanalization for Treatment of Acute Intracerebral Artery OcclusionRoth C, Papanagiotou P, Reith W et al.Stroke, in press
recanalization mRS 0-2 ICH
69.5% 36% 9.8%
72.4% 37.9% 7%
81.6% 25% 11.2%
5%45% (mRS 0-1)100%
90.9% 50% 9%Nov 2010
Mechanical REcanalization with FLOW
Restoration in Acute Ischemic Stroke ReFlow Study
•Monocentric Prospective Trial •40 Patients•Primary endpoint: favourable clinical
outcome at 30 and 90 days (mRS 0 to2)•Solitaire FR Recanalization DeviceSaarland University Hospital, Homburg, Germany