Stem cells, Ageing, Leukemia and Lymphoma (SALL) · Stem cells, Ageing, Leukemia and Lymphoma (SALL) Page 1 of 32 ... Stem cells, Ageing, Leukemia and Lymphoma ... Gerrits A, Li Y,

Stem cells, Ageing, Leukemia and Lymphoma (SALL)

Page 1 of 32

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Geest CR, Zwartkruis FJ, Vellenga E, Coffer PJ, Buitenhuis M. Mammalian target of rapamycin activity is required for expansion of CD34(+) hematopoietic progenitor cells. Haematologica-the Hematology Journal 2009;94(7):901-10.

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Houwerzijl EJ, Pol HWD, Blom NR, van der Want JJL, de Wolf JT, Vellenga E. Erythroid precursors from patients with low-risk myelodysplasia demonstrate ultrastructural features of enhanced autophagy of mitochondria. Leukemia 2009;23(5):886-91.

Jalving M, Schepers H. Induced pluripotent stem cells: Will they be safe? Current Opinion in Molecular Therapeutics 2009;11(4):383-93.


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Kranc KR, Schepers H, Rodrigues NP, Bamforth S, Villadsen E, Ferry H, et al. Cited2 Is an Essential Regulator of Adult Hematopoietic Stem Cells. Cell Stem Cell 2009;5(6):659-65.

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Lowenberg B, Ossenkoppele GJ, van Putten W, Schouten HC, Graux C, Ferrant A, et al. High-Dose Daunorubicin in Older Patients with Acute Myeloid Leukemia. New England Journal of Medicine 2009;361(13):1235-48.

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Rizo A, Olthof S, Han L, Vellenga E, de Haan G, Schuringa JJ. Repression of BMI1 in normal and leukemic human CD34(+) cells impairs self-renewal and induces apoptosis. Blood 2009;114(8):1498-505.

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Roorda BD, ter Elst A, Diks SH, Meeuwsen-de Boer TGJ, Kamps WA, De Bont ESJM. PTK787/ZK 222584 inhibits tumor growth promoting mesenchymal stem cells Kinase activity profiling as powerful tool in functional studies. Cancer Biology & Therapy 2009;8(13):1239-48.

Roorda BD, ter Elst A, Kamps WA, De Bont ESJM. Bone marrow-derived cells and tumor growth: Contribution of bone marrow-derived cells to tumor micro-environments with special focus on mesenchymal stem cells. Critical Reviews in Oncology Hematology 2009;69(3):187-98.

Schaar CG, le Cessie S, Snijder S, Franck PFH, Wijermans PW, Ong C, et al. Long-term follow-up of a population based cohort with monoclonal proteinaemia. British Journal of Haematology 2009;144(2):176-84.

Schraders M, Oeschger S, Kluin PM, Hebeda K, Schuuring E, Groenen PJTA, et al. Hypermutation in mantle cell lymphoma does not indicate a clinical or biological subentity. Modern Pathology 2009;22(3):416-25.

Schwamborn JC, Berezikov E, Knoblich JA. The TRIM-NHL Protein TRIM32 Activates MicroRNAs and Prevents Self-Renewal in Mouse Neural Progenitors. Cell 2009;136(5):913-25.

Sie M, Wagemakers M, Molema G, Mooij JJA, De Bont ESJM, den Dunnen WFA. The angiopoietin 1/angiopoietin 2 balance as a prognostic marker in primary glioblastoma multiforme. Journal of Neurosurgery 2009;110(1):147-55.

Sikkema AH, Diks SH, den Dunnen WFA, ter Elst A, Scherpen FJG, Hoving EW, et al. Kinome Profiling in Pediatric Brain Tumors as a New Approach for Target Discovery. Cancer Research 2009;69(14):5987-95.

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Takada S, Berezikov E, Choi YL, Yamashita Y, Mano H. Potential role of miR-29b in modulation of Dnmt3a and Dnmt3b expression in primordial germ cells of female mouse embryos. Rna-A Publication of the Rna Society 2009;15(8):1507-14.

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Tromp YH, Daenen SMGJ, Sluiter WJ, Vellenga E. The predictive value of interleukin-8 (IL-8) in hospitalised patients with fever and chemotherapy-induced neutropenia. European Journal of Cancer 2009;45(4):596-600.

van 't Veer MB, de Jong D, MacKenzie M, Kluin-Nelemans HC, van Oers MHJ, Zijlstra J, et al. High-dose Ara-C and beam with autograft rescue in R-CHOP responsive mantle cell lymphoma patients. British Journal of Haematology 2009;144(4):524-30.

van der Kaalj MAE, Heutte N, van Echten-Arends J, Raemaekers JMM, Carde P, Noordijk EM, et al. Sperm quality before treatment in patients with early stage Hodgkin's lymphoma enrolled in EORTC-GELA Lymphoma Group trials. Haematologica-the Hematology Journal 2009;94(12):1691-7.

van der Weide K, de Jonge-Peeters SDPW, Kuipers F, Devries EGE, Vellenga E. Combining Simvastatin with the Farnesyltransferase Inhibitor Tipifarnib Results in an Enhanced Cytotoxic Effect in a Subset of Primary CD34(+) Acute Myeloid Leukemia Samples. Clinical Cancer Research 2009;15(9):3076-83.

van Gaal JC, Bastiaannet E, Schaapveld M, Otter R, Kluin-Nelemans JC, De Bont ESJM, et al. Cancer in adolescents and young adults in north Netherlands (1989-2003): increased incidence, stable survival and high incidence of second primary tumours. Annals of Oncology 2009;20(2):365-73.

van Gameren II, van Rijswijk MH, Bijzet J, Vellenga E, Hazenberg BP. Histological regression of amyloid in AL amyloidosis is exclusively seen after normalization of serum free light chain. Haematologica-the Hematology Journal 2009;94(8):1094-100.

van Rij RP, Berezikov E. Small RNAs and the control of transposons and viruses in Drosophila. Trends in Microbiology 2009;17(4):163-71.

van Vilet MJ, Tissing WJE, Rings EHHM, Koetse HA, Stellaard F, Kamps WA, et al. Citrulline as a Marker for Chemotherapy Induced Mucosal Barrier Injury in Pediatric Patients. Pediatric Blood & Cancer 2009;53(7):1188-94.

van Vliet MJ, Tissing WJE, Dun CAJ, Meessen NEL, Kamps WA, De Bont ESJM, et al. Chemotherapy Treatment in Pediatric Patients with Acute Myeloid Leukemia Receiving Antimicrobial Prophylaxis Leads to a Relative Increase of Colonization with Potentially Pathogenic Bacteria in the Gut. Clinical Infectious Diseases 2009;49(2):262-70.

van Vliet MJ, Tissing WJE, De Bont ESJM, Meessen NEL, Kamps WA, Harmsen HJM. Denaturing Gradient Gel Electrophoresis of PCR-Amplified gki Genes: a New Technique for Tracking Streptococci. Journal of Clinical Microbiology 2009;47(7):2181-6.

van Wolfswinkel JC, Claycomb JM, Batista PJ, Mello CC, Berezikov E, Ketting RF. CDE-1 Affects Chromosome Segregation through Uridylation of CSR-1-Bound siRNAs. Cell 2009;139(1):135-48.


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Wang M, Atayar C, Rosati S, Bosga-Bouwer A, Kluin P, Visser L. JNK is constitutively active in mantle cell lymphoma: cell cycle deregulation and polyploidy by JNK inhibitor SP600125. Journal of Pathology 2009;218(1):95-103.

Agool A, Slart RHJA, Dierckx RAJO, Kluin PM, Visser L, Jager PL, et al. Somatostatin receptor scintigraphy might be useful for detecting skeleton abnormalities in patients with multiple myeloma and plasmacytoma. European Journal of Nuclear Medicine and Molecular Imaging 2010;37(1):124-30.

Bachas C, Schuurhuis GJ, Hollink IHIM, Kwidama ZJ, Goemans BF, Zwaan CM, et al. High-frequency type I/II mutational shifts between diagnosis and relapse are associated with outcome in pediatric AML: implications for personalized medicine. Blood 2010;116(15):2752-8.

Balgobind BV, Zwaan CM, Reinhardt D, rentsen-Peters TJCM, Hollink IHIM, de Haas V, et al. High BRE expression in pediatric MLL-rearranged AML is associated with favorable outcome. Leukemia 2010;24(12):2048-55.

Balgobind BV, Lugthart S, Hollink IH, rentsen-Peters STJC, van Wering ER, de Graaf SSN, et al. EVI1 overexpression in distinct subtypes of pediatric acute myeloid leukemia. Leukemia 2010;24(5):942-9.

Berezikov E, Liu N, Flynt AS, Hodges E, Rooks M, Hannon GJ, et al. Evolutionary flux of canonical micrornAs and mirtrons in Drosophila. Nature Genetics 2010;42(1):6-9.

Blacquiere MJ, Timens W, van den Berg A, Geerlings M, Postma DS, Hylkema MN. Maternal smoking during pregnancy decreases Wnt signalling in neonatal mice. Thorax 2010;65(6):553-4.

Broyl A, Hose D, Lokhorst H, de Knegt Y, Peeters J, Jauch A, et al. Gene expression profiling for molecular classification of multiple myeloma in newly diagnosed patients. Blood 2010;116(14):2543-53.

Cervera J, Montesinos P, Hernandez-Rivas JM, Calasanz MJ, Aventin A, Ferro MT, et al. Additional chromosome abnormalities in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and chemotherapy. Haematologica-the Hematology Journal 2010;95(3):424-31.

Correa RL, Steiner FA, Berezikov E, Ketting RF. MicroRNA-Directed siRNA Biogenesis in Caenorhabditis elegans. Plos Genetics 2010;6(4).

de Jonge HJM, Valk PJM, Veeger NJGM, ter Elst A, den Boer ML, Cloos J, et al. High VEGFC expression is associated with unique gene expression profiles and predicts adverse prognosis in pediatric and adult acute myeloid leukemia. Blood 2010;116(10):1747-54.

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Enciso-Mora V, Broderick P, Ma Y, Jarrett RF, Hjalgrim H, Hemminki K, et al. A genome-wide association study of Hodgkin's lymphoma identifies new susceptibility loci at 2p16.1 (REL), 8q24.21 and 10p14 (GATA3). Nature Genetics 2010;42(12):1126-+.

Foijer F. CINister thoughts. Biochemical Society Transactions 2010;38:1715-21.

Gerrits A, Dykstra B, Kalmykowa OJ, Klauke K, Verovskaya E, Broekhuis MJC, et al. Cellular barcoding tool for clonal analysis in the hematopoietic system. Blood 2010;115(13):2610-8.

Han L, Schuringa JJ, Mulder A, Vellenga E. Dasatinib impairs long-term expansion of leukemic progenitors in a subset of acute myeloid leukemia cases. Annals of Hematology 2010;89(9):861-71.

Huang X, van den Berg A, Gao ZF, Visser L, Nolte I, Vos H, et al. Expression of HLA Class I and HLA Class II by Tumor Cells in Chinese Classical Hodgkin Lymphoma Patients. Plos One 2010;5(5).

Huls G, Mulder AB, Rosati S, van de Loosdrecht AA, Vellenga E, de Wolf JTM. Efficacy of single-agent lenalidomide in patients with JAK2 (V617F) mutated refractory anemia with ring sideroblasts and thrombocytosis. Blood 2010;116(2):180-2.

Kamminga LM, Luteijn MJ, den Broeder MJ, Redl S, Kaaij LJT, Roovers EF, et al. Hen1 is required for oocyte development and piRNA stability in zebrafish. Embo Journal 2010;29(21):3688-700.

Kneppers E, Lokhorst HM, Eeltink CM, Huls G, Kersten MJ, Koedam J, et al. Analysis of Efficacy and Prognostic Factors of Lenalidomide Treatment as Part of a Dutch Compassionate Use Program. Clinical Lymphoma Myeloma & Leukemia 2010;10(2):138-43.

Knol HM, Bogchelman DH, Kluin-Nelemans HC, Van der Zee AGJ, van der Meer J, Meijer K. Routine evaluation and treatment of unexplained menorrhagia: do we consider haemostatic disorders? European Journal of Obstetrics & Gynecology and Reproductive Biology 2010;152(2):191-4.

Kooistra SM, van den Boom V, Thummer RP, Johannes F, Wardenaar R, Tesson BM, et al. Undifferentiated Embryonic Cell Transcription Factor 1 Regulates ESC Chromatin Organization and Gene Expression. Stem Cells 2010;28(10):1703-14.

Koster R, di Pietro A, Timmer-Bosscha H, Gibcus JH, van den Berg A, Suurmeijer AJ, et al. Cytoplasmic p21 expression levels determine cisplatin resistance in human testicular cancer. Journal of Clinical Investigation 2010;120(10):3594-605.

Kruyt FAE, Schuringa JJ. Apoptosis and cancer stem cells: Implications for apoptosis targeted therapy. Biochemical Pharmacology 2010;80(4):423-30.

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dexamethasone, and high-dose melphalan, followed by thalidomide maintenance in patients with multiple myeloma. Blood 2010;115(6):1113-20.

Lowenberg B, Beck J, Graux C, van Putten W, Schouten HC, Verdonck LF, et al. Gemtuzumab ozogamicin as postremission treatment in AML at 60 years of age or more: results of a multicenter phase 3 study. Blood 2010;115(13):2586-91.

Lugthart S, Groschel S, Beverloo HB, Kayser S, Valk PJM, van Zelderen-Bhola SL, et al. Clinical, Molecular, and Prognostic Significance of WHO Type inv(3)(q21q26.2)/t(3;3)(q21;q26.2) and Various Other 3q Abnormalities in Acute Myeloid Leukemia. Journal of Clinical Oncology 2010;28(24):3890-8.

Mahmoodi BK, Brouwer JLP, ten Kate MK, Lijfering WM, Veeger NJGM, Mulder AB, et al. A prospective cohort study on the absolute risks of venous thromboembolism and predictive value of screening asymptomatic relatives of patients with hereditary deficiencies of protein S, protein C or antithrombin. Journal of Thrombosis and Haemostasis 2010;8(6):1193-200.

Mulder GM, Nijboer WN, Seelen MA, Sandovici M, Bos EM, Melenhorst WBWH, et al. Heparin binding epidermal growth factor in renal ischaemia/reperfusion injury. Journal of Pathology 2010;221(2):183-92.

Mulder R, van Schouwenburg IM, Mahmoodi BK, Veeger NJGM, Mulder AB, Middeldorp S, et al. Associations between high factor VIII and low free protein S levels with traditional arterial thrombotic risk factors and their risk on arterial thrombosis: Results from a retrospective family cohort study. Thrombosis Research 2010;126(4):E249-E254.

Mulder R, ten Kate MK, Kluin-Nelemans HC, Mulder AB. Low cut-off values increase diagnostic performance of protein S assays. Thrombosis and Haemostasis 2010;104(3):618-25.

paricio-Vergara M, Shiri-Sverdlov R, de Haan G, Hofker MH. Bone marrow transplantation in mice as a tool for studying the role of hematopoietic cells in metabolic and cardiovascular diseases. Atherosclerosis 2010;213(2):335-44.

Pott C, Hoster E, fau-Larue MH, Beldjord K, Bottcher S, Asnafi V, et al. Molecular remission is an independent predictor of clinical outcome in patients with mantle cell lymphoma after combined immunochemotherapy: a European MCL intergroup study. Blood 2010;115(16):3215-23.

Rizo A, Horton SJ, Olthof S, Dontje B, Ausema A, van Os R, et al. BMI1 collaborates with BCR-ABL in leukemic transformation of human CD34(+) cells. Blood 2010;116(22):4621-30.

Robertus JL, Kluiver J, Weggemans C, Harms G, Reijmers RM, Swart Y, et al. MiRNA profiling in B non-Hodgkin lymphoma: a MYC-related miRNA profile characterizes Burkitt lymphoma. British Journal of Haematology 2010;149(6):896-9.


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Roeloffzen WH, Kluin-Nelemans HC, Bosman L, de Wolf JTM. Effects of red blood cells on hemostasis. Transfusion 2010;50(7):1536-44.

Roeloffzen WWH, Kluin-Nelemans HC, Veeger NJGM, Bosman L, de Wolf JTM. Transfused stored platelets have the same haemostatic function as circulating native platelets. Vox Sanguinis 2010;99(2):123-30.

Roeloffzen WWH, Kluin-Nelemans HC, Mulder AB, de Wolf JTM. Thrombocytopenia affects plasmatic coagulation as measured by thrombelastography. Blood Coagulation & Fibrinolysis 2010;21(5):389-97.

Roeloffzen WWH, Kluin-Nelemans HC, Mulder AB, Veeger NJGM, Bosman L, de Wolf JTM. In Normal Controls, Both Age and Gender Affect Coagulability as Measured by Thrombelastography. Anesthesia and Analgesia 2010;110(4):987-94.

Roorda BD, ter Elst A, Meeuwsen-de Boer TGJ, Kamps WA, De Bont ESJM. Mesenchymal Stem Cells Contribute to Tumor Cell Proliferation by Direct Cell-Cell Contact Interactions. Cancer Investigation 2010;28(5):526-34.

Roorda BD, ter Elst A, Scherpen FJG, Meemusen-de Boer TGJ, Kamps WA, De Bont ESJM. VEGF-A promotes lymphoma tumour growth by activation of STAT proteins and inhibition of p27(KIP1) via paracrine mechanisms. European Journal of Cancer 2010;46(5):974-82.

Roy S, Ernst J, Kharchenko PV, Kheradpour P, Negre N, Eaton ML, et al. Identification of Functional Elements and Regulatory Circuits by Drosophila modENCODE. Science 2010;330(6012):1787-97.

Schaapveld M, Visser O, Siesling S, Schaar CG, Zweegman S, Vellenga E. Improved survival among younger but not among older patients with Multiple Myeloma in the Netherlands, a population-based study since 1989. European Journal of Cancer 2010;46(1):160-9.

Schuringa JJ. Tracing C/EBP alpha(+) cells and their progeny. Blood 2010;116(20):4038-9.

Schuringa JJ, Vellenga E. Role of the polycomb group gene BMI1 in normal and leukemic hematopoietic stem and progenitor cells. Current Opinion in Hematology 2010;17(4):294-9.

Schuurmans M, Bromberg JEC, Doorduijn J, Poortmans P, Taphoorn MJB, Seute T, et al. Primary central nervous system lymphoma in the elderly: a multicentre retrospective analysis. British Journal of Haematology 2010;151(2):179-84.

Seigers R, Timmermans J, van der Horn HJ, de Vries EFJ, Dierckx RA, Visser L, et al. Methotrexate reduces hippocampal blood vessel density and activates microglia in rats but does not elevate central cytokine release. Behavioural Brain Research 2010;207(2):265-72.


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Sie M, De Bont ESJM, Scherpen FJG, Hoving EW, den Dunnen WFA. Tumour vasculature and angiogenic profile of paediatric pilocytic astrocytoma; is it much different from glioblastoma? Neuropathology and Applied Neurobiology 2010;36(7):636-47.

Slagman MCJ, Sinkeler SJ, Hemmelder MH, Waanders F, Vogt L, Kluin-Nelemans HC, et al. Erythropoietin is reduced by combination of diuretic therapy and RAAS blockade in proteinuric renal patients with preserved renal function. Nephrology Dialysis Transplantation 2010;25(10):3256-60.

Slagman MCJ, Sinkeler SJ, Hemmelder MH, Waanders F, Vogt L, Kluin-Nelemans HC, et al. RAAS blockade in combination with diuretic therapy increases urine excretion, which in turn increases drinking and thus reduces erythropoietin and proteinuria - Reply. Nephrology Dialysis Transplantation 2010;25(7):2384.

Slezak-Prochazka I, Durmus S, Kroesen BJ, van den Berg A. MicroRNAs, macrocontrol: Regulation of miRNA processing. Rna-A Publication of the Rna Society 2010;16(6):1087-95.

Tallman MS, Kim HT, Montesinos P, Appelbaum FR, de la Serna J, Bennett JM, et al. Does microgranular variant morphology of acute promyelocytic leukemia independently predict a less favorable outcome compared with classical M3 APL? A joint study of the North American Intergroup and the PETHEMA Group. Blood 2010;116(25):5650-9.

Tichelaar YIGV, Knol HM, Mulder AB, Kluin-Nelemans JC, Lijfering WM. Association between deep vein thrombosis and transient inflammatory signs and symptoms: a case-control study. Journal of Thrombosis and Haemostasis 2010;8(8):1874-6.

Valent P, Arock M, Akin C, Sperr WR, Reiter A, Sotlar K, et al. The classification of systemic mastocytosis should include mast cell leukemia (MCL) and systemic mastocytosis with a clonal hematologic non-mast cell lineage disease (SM-AHNMD). Blood 2010;116(5):850-1.

van der Kaaij MAE, van Echten-Arends J, Simons AHM, Kluin-Nelemans HC. Fertility preservation after chemotherapy for Hodgkin lymphoma. Hematological Oncology 2010;28(4):168-79.

van Gameren II, Hazenberg BPC, Bijzet J, Haagsma EB, Vellenga E, Posthumus MD, et al. Amyloid Load in Fat Tissue Reflects Disease Severity and Predicts Survival in Amyloidosis. Arthritis Care & Research 2010;62(3):296-301.

van Harn T, Foijer F, van Vugt M, Banerjee R, Yang FT, Oostra A, et al. Loss of Rb proteins causes genomic instability in the absence of mitogenic signaling. Genes & Development 2010;24(13):1377-88.

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Stem cells, Ageing, Leukemia and Lymphoma (SALL) · Stem cells, Ageing, Leukemia and Lymphoma (SALL) Page 1 of 32 ... Stem cells, Ageing, Leukemia and Lymphoma ... Gerrits A, Li Y,