• State that enzymes are globular proteins with a specific tertiary structure.

• State that enzymes catalyse metabolic reactions in living organisms.

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Week 18

Primary structure to tertiary structure in enzymes

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Week 18

Commercial application of enzymes

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Week 18

• State that enzyme action may be extracellular or intracellular.

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Week 18

Mould produces extracellular enzymes to digest bread

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Week 18

Lysosome and phagocytosis

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Week 18

• Describe the mechanism of enzyme action with reference to specificity, active site, lock-and-key and induced-fit hypotheses.

• Explain what is meant by enzyme–substrate complex and enzyme–product complex.

• Describe how enzymes lower the activation energy of a reaction.

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Week 18

• State that enzymes are globular proteins with a specific tertiary structure.

• State that enzymes catalyse metabolic reactions in living organisms.

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Week 18

Activation energy (maltose to glucose)

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Week 18

How the enzyme maltase lowers the activation energy needed to convert

maltose to glucose

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Week 18

The lock-and-key hypothesis

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Week 18

The induced-fit hypothesis

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Week 18

• Enzymes and metabolism – an overview

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Week 18

A metabolic pathway

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Week 18

Phenylketonuria sequence and effects

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Week 18

Co-factors and co-enzymes

• Some enzymes will only work if there is another non-protien substance bound to them. These non-protein substances are called Co-factors– Use your text book to give an example

• Some co-factors are organic molecules these are called co-enzymes. They participate in the reaction and are changed by it. They often act as carriers, moving chemical groups between different enzymes. They’re continually recycled during this process.– Use your text book to give an example