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8/12/2019 Spinal Manipulative Therapy Reduces Central Pain Sensitization
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28/2/2014 Spinal manipulative therapy reduces central pain sensitization -- ScienceDaily
http://www.sciencedaily.com/releases/2014/02/140225122220.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2… 1/1
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American Pain Society. "Spinal manipulative therapy reduces central pain sensitization." ScienceDaily.ScienceDaily, 25 February 2014. <www.sciencedaily.com/releases/2014/02/140225122220.htm>.
Spinal manipulative therapy reduces central pain sensitization
February 25, 2014
American Pain Society
The lessening of pain sensitivity achieved with spinal manipulation therapy (SMT) occurs as a result of the treatmentand not as much from a placebo effect caused by the expectation of receiving SMT, according to a study publishedin The Journal of Pain.
Spinal manipulative therapy has been shown to reduce the severity of low back pain in some patients. Improvedunderstanding of its pain-relieving mechanisms could enhance clinical effectiveness.
Chronic low back pain is associated with altered pain processing, suggesting a mechanism related to centralsensitization of pain. Central sensitization is considered a factor in the progression of acute pain to chronic pain andin the maintenance of chronic pain.
Researchers from the University of Florida investigated whether lessening of pain sensitivity attributed to SMT isspecific to the procedure itself or occurs as a placebo effect from treatment expectation. Studies have shown thatplacebo is associated with robust analgesia produced by anticipation of pain relief.
Subjects for the study had low back pain and were recruited from the University of Florida campus. Participantsunderwent baseline pressure and thermal pain testing and were randomly assigned to SMT, placebo SMT, enhancedplacebo SMT (same as placebo SMT except subjects were informed they would get SMT or a placebo intervention)or no intervention. The 110 study subjects had repeat mechanical and thermal pain sensitivity testing to measureimmediate, within session, change in pain sensitivity.
Results showed that significantly more participants receiving the enhanced placebo SMT indicated good to excellentoutcomes than those receiving standard placebo SMT or no treatment. A significant difference was not found
between subjects receiving SMT and the enhanced placebo.The authors concluded their findings reveal a mechanism of SMT unrelated to the expectation of receiving SMT, butfrom modulation of dorsal horn excitability and lessening of central sensitization. This suggests potential for SMT tobe a clinically beneficial intervention.
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The above story is based on materials provided by American Pain Society. Note: Materials may be edited for content and length.
Journal Reference:
1. Joel E. Bialosky, Steven Z. George, Maggie E. Horn, Donald D. Price, Roland Staud, Michael E. Robinson.Spinal Manipulative Therapy–Specific Changes in Pain Sensitivity in Individuals With Low Back Pain(NCT01168999). The Journal of Pain, 2014; 15 (2): 136 DOI: 10.1016/j.jpain.2013.10.005
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